Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| effect of continuous compressions and 30:2 cardiopulmonary resuscitation on global ventilation/perfusion values during resuscitation in a porcine model. | rescue ventilations during bystander resuscitation, although previously considered essential, interrupt the continuity of chest compressions and might have deleterious effects in basic life support. this study was undertaken to analyze the global ventilation/perfusion values of continuous compressions and 30:2 cardiopulmonary resuscitation to determine the effectiveness for each approach in a porcine model of prolonged bystander cardiopulmonary resuscitation for ventricular fibrillation. | 2010 | 20683258 |
| chondroitin sulfate demarcates astrocytic territories in the mammalian cerebral cortex. | adjacent astrocytes in the grey matter of the mammalian cerebral cortex are organized in a tile-like manner and separated from one another, forming discrete domains named "non-overlapping territories". we have previously reported that an anti-chondroitin sulfate (cs) antibody, cs-56, marks a subpopulation of cortical astrocytes which we named the dandelion clock-like structure (dacs) based on its morphological characteristics. in the present study, we found that another anti-cs antibody (anti-cs ... | 2010 | 20678547 |
| in vitro permeation of a pegylated naltrexone prodrug across microneedle-treated skin. | microneedles (mn) are a useful tool for increasing skin permeability to xenobiotics. previous research showed marked improvement in the percutaneous flux of naltrexone (ntx) hydrochloride by the use of mn skin pretreatment alone; however, for better therapeutic effect, further enhancement is desired. the goal of this in vitro study was to combine microneedle skin pretreatment with the use of a highly water-soluble pegylated naltrexone prodrug (polyethyleneglycol-ntx, peg-ntx) to investigate its ... | 2010 | 20678989 |
| comparative pathology of select agent influenza a virus infections. | influenza a virus infections may spread rapidly in human populations and cause variable mortality. two of these influenza viruses have been designated as select agents: 1918 h1n1 virus and highly pathogenic avian influenza (hpai) virus. knowledge of the pathology of these virus infections in humans, other naturally infected species, and experimental animals is important to understand the pathogenesis of influenza, to design appropriate models for evaluation of medical countermeasures, and to mak ... | 2010 | 20682805 |
| analysis of 11 tetrameric strs in wild boars for forensic purposes. | str profiling of animal species has a wide range of applications, including forensic identification, wildlife preservation, veterinary public health protection and food safety. we tested the efficacy of a multiplex pcr-based assay including 11 porcine-specific tetrameric strs in a population sample of wild boars (n=142) originating from piedmont (north west italy). multiple deviations from hardy-weinberg expectations were observed, mostly due to a reduction in observed heterozygosity indicative ... | 2010 | 20685189 |
| the rethink project--minipigs as models for the toxicity testing of new medicines and chemicals: an impact assessment. | the objective of the rethink project was to evaluate the potential impact of toxicity testing in the minipig as an alternative approach in regulatory toxicity testing that can contribute to the replacement, refinement and reduction of animal testing (3rs). minipigs are strains of domestic pigs that are markedly smaller than farmyard varieties, and thus better adapted to laboratory housing. the pig closely resembles man in many features of its anatomy, physiology, biochemistry and lifestyle. in p ... | 2010 | 20685395 |
| ochrobactrum pecoris sp. nov., isolated from farm animals. | two gram-negative, rod-shaped, non-spore-forming strains, 08rb2639(t) and 08rb2781-1 isolated from sheep (ovis aries) and boar (sus scrofa domestica), respectively, were studied for their taxonomic position. by 16s rrna gene sequencing, these strains revealed identical sequences and were shown to belong to the alphaproteobacteria with 97.8 % sequence similarity to ochrobactrum rhizosphaerae pr17(t), ochrobactrum pituitosum ccug 50899(t) , ochrobactrum tritici scii24(t) and ochrobactrum haematoph ... | 2010 | 20952542 |
| experimental study of pancreaticojejunostomy completed using anastomotic chains. | the most difficult, time-consuming, and complication-prone step in pancreaticoduodenectomy is the pancreaticojejunostomy step. the largest disadvantage of this kind of anastomosis is the high incidence of postoperative anastomotic leakage. once pancreatic leakage occurs, the patient death rate can be very high. the aim of this study was to design a pancreaticojejunostomy procedure using anastomotic chains, which results in the cut end of the jejunum being attached to the pancreatic stump without ... | 2010 | 20687743 |
| prevalence of actinobacillus pleuropneumoniae infection in hunted wild boars (sus scrofa) in germany. | actinobacillus pleuropneumoniae is an important pathogen of the porcine respiratory tract. subclinically and chronically infected pigs may enter a permanent carrier state, harboring a. pleuropneumoniae in lungs or tonsils. despite the enormous role of a. pleuropneumoniae in domestic swine production, no published data about prevalence and distribution of a. pleuropneumoniae infections in wild boars (sus scrofa) are available. antibodies against a. pleuropneumoniae have been detected in serum of ... | 2010 | 20688648 |
| a three-dimensional digital segmented and deformable brain atlas of the domestic pig. | we used high-magnetic field (4.7 t) magnetic resonance imaging (mri) to build the first high-resolution (100 microm x 150 microm x 100 microm) three-dimensional (3d) digital atlas in stereotaxic coordinates of the brain of a female domestic pig (sus scrofa domesticus). this atlas was constructed from one hemisphere which underwent a symmetrical transformation through the midsagittal plane. concomitant construction of a 3d histological atlas based on the same scheme facilitated control of deep br ... | 2010 | 20692291 |
| examination of protective effect of ischemic postconditioning after small bowel autotransplantation. | ischemia/reperfusion (i/r) injury is a serious condition that results from some surgical procedures, including intestinal transplantation. ischemic postconditioning is defined as brief periods of reperfusion alternating with reocclusion applied during the early minutes after reperfusion. the objective of this study was to investigate the effect of ischemic postconditioning before small bowel autotransplantation. total orthotopic intestinal autotransplantation was performed in 30 white domestic p ... | 2010 | 20692464 |
| a biochemical comparison of the in vivo effects of bulbine frutescens and bulbine natalensis on cutaneous wound healing. | in south africa the local population relies extensively on indigenous plants in the formulation of traditional medicines to treat skin ailments. the scientific merits of many of these plants used to treat wounds and burns are yet to be validated. bulbine natalensis and bulbine frutescens of the asphodelaceae family are indigenous to only southern africa and are widely used as a skin remedy. this study aimed to explore the scientific value of these plants through investigating the in vivo biochem ... | 2010 | 20937372 |
| next-generation sequencing of the trichinella murrelli mitochondrial genome allows comprehensive comparison of its divergence from the principal agent of human trichinellosis, trichinella spiralis. | the mitochondrial genome's non-recombinant mode of inheritance and relatively rapid rate of evolution has promoted its use as a marker for studying the biogeographic history and evolutionary interrelationships among many metazoan species. a modest portion of the mitochondrial genome has been defined for 12 species and genotypes of parasites in the genus trichinella, but its adequacy in representing the mitochondrial genome as a whole remains unclear, as the complete coding sequence has been char ... | 2010 | 20946970 |
| coronary bare metal stent implantation in homozygous ldl receptor deficient swine induces a neointimal formation pattern similar to humans. | to date, most of all new developments in stent technologies are tested in normal animals. although invaluable in the evaluation of device safety, the juvenile domestic swine (ds) do not follow the biological healing response occurring in humans following coronary stent implantation. by using a novel swine breed afflicted with familial hypercholesterolemia (fhs), we aimed to analyse the vascular response occurring following bare metal stent (bms) implantation by comparing in vivo endovascular ima ... | 2010 | 20950808 |
| magnetically controllable gastrointestinal steering of video capsules. | wireless capsule endoscopy (wce) allows for comfortable video explorations of the gastrointestinal (gi) tract, with special indication for the small bowel. in the other segments of the gi tract also accessible to probe gastroscopy and colonscopy, wce still exhibits poorer diagnostic efficacy. its main drawback is the impossibility of controlling the capsule movement, which is randomly driven by peristalsis and gravity. to solve this problem, magnetic maneuvering has recently become a thrust rese ... | 2010 | 20952324 |
| an elisa based on a truncated soluble orf2 protein for the detection of pcv2 antibodies in domestic pigs. | postweaning multisystemic wasting syndrome (pmws) is an important swine disease that is closely associated with porcine circovirus type 2 (pcv2). the capsid protein (cap protein) is a major structural protein that has at least three immunoreactive regions, and it can be a suitable candidate antigen for detecting the specific antibodies of a pcv2 infection. in the present study, an indirect enzyme-linked immunosorbent assay (tcelisa) based on a truncated soluble cap protein produced in escherichi ... | 2010 | 20960293 |
| left ventricular pacing lead insertion via the coronary sinus cardioplegia cannula: a novel method for temporary biventricular pacing during reoperative cardiac surgery. | objective: temporary biventricular pacing to treat low output states after cardiac surgery is an active area of investigation. reoperative cases are not studied due to adhesions, which preclude left ventricular mobilization to place epicardial pacing wires. in such patients, inserting a temporary left ventricular lead via the coronary sinus cardioplegia cannula may allow for biventricular pacing. we developed a novel technique for intraoperative left ventricular lead placement. methods: eight do ... | 2010 | 20965517 |
| prevalence and genotypes of toxoplasma gondii in feline faeces (oocysts) and meat from sheep, cattle and pigs in switzerland. | the protozoan parasite toxoplasma gondii infects almost all warm blooded animal species including humans, and is one of the most prevalent zoonotic parasites worldwide. post-natal infection in humans is acquired through oral uptake of sporulated t. gondii oocysts or by ingestion of parasite tissue cysts upon consumption of raw or undercooked meat. this study was undertaken to determine the prevalence of oocyst-shedding by cats and to assess the level of infection with t. gondii in meat-producing ... | 2010 | 21183278 |
| african swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and adult warthogs, respectively, at a single geographical site. | the role of the ancestral sylvatic cycle of the african swine fever virus (asfv) is not well understood in the endemic areas of eastern africa. we therefore analysed the asf infection status on samples collected from 51 free-ranging warthogs (phacocherus africanus) and 1576 ornithodorus porcinus ticks from 26 independent warthog burrows at a single ranch in kenya. abattoir samples from 83 domestic pigs without clinical symptoms, originating from specific locations with no recent reported asf out ... | 2010 | 20965989 |
| [changes in myocardial connexin 43 during ventricular fibrillation]. | to observe changes in connexin 43 (cx43) after ventricular fibrillation (vf) and the effects of rotigaptide (zp123) on cx43. | 2010 | 20977841 |
| a 6-bp deletion in the tyrp1 gene causes the brown colouration phenotype in chinese indigenous pigs. | brown coat colour has been described in chinese-tibetan, kele, and dahe pigs. here, we report the identification of a causal mutation underlying the brown colouration. we performed a genome-wide association study (gwas) on tibetan and kele pigs, and found that brown colours in chinese breeds are controlled by a single locus on pig chromosome 1. by using a haplotype-sharing analysis, we refined the critical region to a 1.5-mb interval that encompasses only one pigmentation gene: tyrosinase-relate ... | 2010 | 20978532 |
| virulence genes and plasmid profiles in rhodococcus equi isolates from domestic pigs and wild boars (sus scrofa) in brazil. | the virulence genes and plasmid profiles of 23 rhodococcus equi isolates from 258 lymph nodes from domestic pigs (129 nodes with lesions and 129 without lesions) and 120 lymph nodes from slaughtered wild boars (60 nodes with lesions and 60 without) were characterized. r. equi was obtained from 19 lymph nodes of domestic pigs, 17 with, and two without lesions, and from four lymph nodes with lesions, from wild boars. the 23 isolates were tested for the presence of vapa and vapb genes, responsible ... | 2010 | 20980033 |
| novel robotic da vinci instruments for laparoendoscopic single-site surgery. | to describe novel robotic laparoendoscopic single-site surgery (r-less) instruments, and present the initial laboratory experience in urology. | 2010 | 20980046 |
| comparative study of the osseointegration of dental implants after different bone augmentation techniques: vascularized femur flap, non-vascularized femur graft and mandibular bone graft. | objectives: the purpose of this study was to evaluate the osseointegration of the dental implants placed into the mandible augmented with different techniques in pigs. material and methods: four adult domestic pigs were used. horizontal augmentation of the mandible was performed in animals by using vascularized femur flap (vff), non-vascularized femur graft (nvfg) and monocortical mandibular block graft (mg). after 5 months of healing 10 dental implants were placed into each augmented site. the ... | 2010 | 21044163 |
| cloning, characterization and diagnostic performance of the salivary lipocalin protein tsgp1 from ornithodoros moubata. | the argasid tick ornithodoros moubata is distributed throughout south and east africa and madagascar, where it colonizes wild and domestic habitats and feeds on warthogs, domestic swine, and humans. this argasid transmits the spirochete borrelia duttonii, causing east african tick-borne relapsing fever in humans, and the african swine fever virus, which causes a highly lethal haemorrhagic disease in pigs. tick surveillance and the elimination of o. moubata from synanthropic environments (human d ... | 2010 | 21216104 |
| nucleotide variability of the porcine serpina6 gene and the origin of a putative causal mutation associated with meat quality. | the serpin peptidase inhibitor, clade a, member 6 gene (serpina6), also known as corticosteroid-binding globulin or cbg, is involved in obesity and stress sensitivity. previous studies have reported putative causal mutations within that gene in the porcine species. to characterize a hypothetical selective footprint, we have resequenced approximately 6 kb of coding and non-coding fragments in 20 pigs comprising domestic breeds and wild boars from asia and europe. nucleotide variability was found ... | 2010 | 21054451 |
| hybrid transureteral natural orifice translumenal endoscopic nephrectomy: a feasibility study in the porcine model. | natural orifice approaches for nephrectomy have included access via the stomach, vagina, bladder, and rectum. the use of the ureter as a natural orifice for natural orifice translumenal endoscopic surgery (notes) nephrectomy has not been previously reported. the purpose of this study is to test the feasibility of transureteral laparoscopic notes nephrectomy. | 2010 | 21058889 |
| noninvasive mr characterization of structural and functional components of reperfused infarct. | left ventricular (lv) remodeling is a highly complex phenomenon that starts soon after infarction and progresses to extensive regional and global architectural changes over time. | 2010 | 21062130 |
| genetic variations and sequences analysis of mtatp6 and mtatp8 genes among different chinese pig breeds. | to investigate the genetic variations of mtatp6 and mtatp8 genes among different chinese pig breeds, two fragments of 425 and 743 bp containing the whole coding region of mtatp8 and mtatp6 genes were amplified with 805 individuals from 23 chinese local pig breeds, three types of chinese wild boars and three european pig breeds. sequence comparison identified a total number of 17 substitutions including six variable sites in mtatp8 and eleven substitutions in mtatp6 gene. the restriction enzyme f ... | 2010 | 21077971 |
| prevalence of porcine circoviruses in transylvanian wild boars, detected by real-time pcr--short communication. | porcine circoviruses (pcv) are widespread in domestic pigs worldwide and there is growing information about the presence of pcv in other suid species. based on serological studies with sera of wild boars, it was established that pcv1 was present in these animals and antibodies specific to pcv2 were also detected in wild boars living in captivity or in sylvatic areas, both with or without clinical signs of pmws. studies including pcv2 genome or antigen detection confirmed the previous findings. t ... | 2010 | 21087917 |
| mechanical chest compressions with trapezoidal waveform improve haemodynamics during cardiac arrest. | during manual chest compressions for cardiac arrest the waveforms of chest compressions are generally sinusoidal, whereas mechanical chest compression devices can have different waveforms, including trapezoidal. we studied the haemodynamic differences of such waveforms in a porcine model of cardiac arrest. | 2010 | 21093141 |
| gene expression of serotonin and dopamine receptors and monoamine oxidase-a in the brain of dominant and subordinate pubertal domestic pigs (sus scrofa) fed a β-adrenoreceptor agonist. | aggression is a major source of social stress with negative effects on health and well-being, yet limited information is known about the molecular mechanisms mediating aggressive behavior in swine. ractopamine (rac) is a β-adrenoreceptor agonist that enhances growth but increases aggressive behaviors in female pigs. thus, the effects of rac, sex, and social rank on the mrna abundance of genes encoding serotonin and dopamine receptors, and monoamine oxidase (mao)-a in brains of sub-adult pigs wer ... | 2010 | 21094150 |
| an on-farm survey of spatial and temporal stratifications of 17β-estradiol concentrations. | 17β-estradiol (e2) is a natural estrogenic hormone found in animal manure and urine, which may cause endocrine disruption in sensitive organisms. 17β-estradiol has been widely detected in the environment, and animal agriculture may be an important source. the objectives of this study were to investigate the potential sources and/or spatial and temporal characteristics contributing to detections of e2 at the farm-scale. soil cores, segmented into 0.15m increments, were taken down to the water tab ... | 2010 | 21094971 |
| vertebral column, rib and sternal muscles of sulawesi babirusa (babyrousa celebensis). | the muscular anatomy of the vertebrae, ribs and sternebrae of the sulawesi babirusa (babyrousa celebensis) is described. there are many similarities to the anatomy of the domestic pig (sus scrofa). however, unlike other pigs, the m. spinalis et semispinalis cervicis et thoracis has an origin from the twelfth thoracic mamillary process. similarly, the babyrousa does not have the lumbar part of the m. obliquus internus abdominis which is found in other pigs. the m. sacrocaudalis dorsalis medialis ... | 2010 | 21108656 |
| first detection of african swine fever virus in ornithodoros porcinus in madagascar and new insights into tick distribution and taxonomy. | abstract: | 2010 | 21118485 |
| reassortant between human-like h3n2 and avian h5 subtype influenza a viruses in pigs: a potential public health risk. | human-like h3n2 influenza viruses have repeatedly been transmitted to domestic pigs in different regions of the world, but it is still uncertain whether any of these variants could become established in pig populations. the fact that different subtypes of influenza viruses have been detected in pigs makes them an ideal candidate for the genesis of a possible reassortant virus with both human and avian origins. however, the determination of whether pigs can act as a "mixing vessel" for a possible ... | 2010 | 20830295 |
| establishment of a porcine model for lobar lung auto-transplantation. | the aim of this study was to develop a porcine model of left single lung auto-transplantation. | 2010 | 20832588 |
| camp-activated ca2+ signaling is required for cftr-mediated serous cell fluid secretion in porcine and human airways. | cystic fibrosis (cf), which is caused by mutations in cftr, affects many tissues, including the lung. submucosal gland serous acinar cells are primary sites of fluid secretion and cftr expression in the lung. absence of cftr in these cells may contribute to cf lung pathogenesis by disrupting fluid secretion. here, we have isolated primary serous acinar cells from wild-type and cftr-/- pigs and humans without cf to investigate the cellular mechanisms and regulation of fluid secretion by optical i ... | 2010 | 20739756 |
| a study on repair of porcine articular cartilage defects with tissue-engineered cartilage constructed in vivo by composite scaffold materials. | the study was performed to find out a promising injectable composite scaffold for cartilage tissue engineering. by using a composite of allogenous cartilage microparticle acellular tissue matrix (cmactm) and fibrin glue (fg) as injectable scaffold materials, tissue-engineered cartilage was constructed in vivo, and the effects of which on the repair of porcine articular cartilage defects were observed. cmactm was obtained from domestic pigs. the chondrocytes were prepared from experimental mini-t ... | 2010 | 20798625 |
| confirmation of needle cricothyroidotomy using an esophageal detector device in a porcine model. | the difficult intubation is one of the most trying situations encountered in airway management. transtracheal jet ventilation via needle cricothyroidotomy can provide temporary oxygenation in this critical situation in a minimally invasive fashion. the esophageal detector device (edd) has been previously shown to be effective in determining the tracheal placement of endotracheal tubes. in this experiment, three commonly available edds are utilized to accurately identify 15 of 15 intratracheal pl ... | 2010 | 20882932 |
| a novel device for rapid cleaning of poorly prepared colons. | adequate colon preparation is essential for the quality and accuracy of colonoscopy and has a significant influence on related costs. the aim of this study was to assess the efficacy and safety of a novel attachable colon-cleaning device used during colonoscopies in porcine colon. | 2010 | 20886401 |
| the effect of nesting material on the nest-building and maternal behavior of domestic sows and piglet production. | nest building is an important part of maternal behavior in domestic pigs. the aim of the study was to assess the effect of nesting material sawdust vs. straw on sow behavior 24 h before and after birth of the first piglet (bfp) and piglet production. sows, housed in farrowing crates, were randomly divided into 2 treatments: sawdust (n = 12) and straw (n = 13). sawdust and straw were provided during the pre- and parturient period; after parturition, straw was given to both experimental groups. th ... | 2010 | 20889685 |
| meiotic studies in infertile domestic pig-babirusa hybrids. | mating of a babirusa (babyrousa babyrussa) boar and a domestic sow (sus scrofa) resulted in the birth of 5 live domestic pig-babirusa hybrid piglets. chromosome analysis of one of the surviving males confirmed that they were domestic pig-babirusa hybrids by revealing the presence of a complete haploid set of 19 porcine chromosomes as well as a complete haploid set of 19 babirusa chromosomes in the karyotype. none of the surviving piglets, two males and one female, had shown signs of sexual matur ... | 2010 | 20924163 |
| identification of a novel astrovirus in a domestic pig in hungary. | the family astroviridae consists of two genera, avastrovirus and mamastrovirus, whose members are associated with gastroenteritis in avian and mammalian hosts, respectively. we serendipitously identified a novel porcine astrovirus in a fecal specimen from a domestic pig (sus scrofa domestica) in hungary. sequencing of a fragment indicated that it was an orf1b/orf2/3'utr sequence, and it has been submitted to the database as porcine astrovirus type 2 (pastv-2/hungary/2007) with accession number g ... | 2010 | 20931250 |
| feasibility and safety of endoscopic transesophageal access and closure using a maryland dissector and a self-expanding metal stent. | background: secure access and reliable closure is paramount in the setting of transesophageal mediastinal endoscopic surgery. the purpose of this study was to develop a secure transesophageal access technique and to evaluate the feasibility, safety, and efficacy of a novel covered, self-expanding, retractable stent for closure of 15-mm esophageal defects. methods: fifteen-millimeter esophagotomies were created in 18 domestic pigs using needle knife puncture and balloon dilatation or a blunt diss ... | 2010 | 21136086 |
| characterization of plasma triiodophenol binding proteins in vertebrates and tissue distribution of triiodophenol in rana catesbeiana tadpoles. | we investigated the interaction of 2,4,6-triiodophenol (tip), a potent thyroid hormone disrupting chemical, with serum proteins from rainbow trout (onchorhynchus mykiss), bullfrog (rana catesbeiana), chicken (gallus gallus), pig (sus scrofa domesticus), and rat (rattus norvegicus) using a [(125)i]tip binding assay, gel filtration chromatography, and native polyacrylamide gel electrophoresis. [(125)i]tip bound non-specifically to proteins in trout serum, specifically but weakly to proteins in bul ... | 2010 | 21147258 |
| comparison of purified olive oil and silver sulfadiazine in the treatment of partial thickness porcine burns. | introduction: burns are widespread in the developed world, and expensive burn dressings are not universally available. most burn patients suffer from a partial thickness burn that can be treated conservatively. nevertheless, the ideal dressing for the burn wound has not been identified. we performed an animal experiment to compare the healing of partial thickness burns treated with silver sulfadiazine (ssd) and olive oil. methods: a randomized controlled animal experiment was conducted on 3 anes ... | 2010 | 21159471 |
| prins detection of 18s rdna in pig, red fox and chinese raccoon dog, and centromere dna in horse. | the fluorescence in situ hybridization (fish) technique is widely used in animal cytogenetics. contrary to fish procedure, primed in situ dna synthesis (prins) does not require the dna probe preparation (design, synthesis, gel purification of pcr products and labeling). the prins method with primers used as 'dna probes' is both pcr-sensitive and allows for chromosomal localization of dna sequences. here, we show the application of prins reaction with one unlabeled oligonucleotide pair to identif ... | 2010 | 21166802 |
| experimental infection of common warthogs (phacochoerus africanus) and bushpigs (potamochoerus larvatus) with classical swine fever virus ii: a comparative histopathological study. | wild african suidae, the common warthog (phacochoerus africanus) and bushpig (potamochoerus larvatus), were experimentally infected with classical swine fever (csf) virus following the diagnosis of csf subtype 2.1 in domestic pigs in south africa in 2005. no data regarding the susceptibility or potential lesions of these african wild suids are available. seven subadult warthogs and six bushpigs were captured and infected intranasally with the south african isolate. two in-contact control animals ... | 2010 | 21176120 |
| effects of human perturbation on the genetic make-up of an island population: the case of the sardinian wild boar. | game species are often manipulated by human beings, whose activities can deeply affect their genetic make-up and population structure. we focused on a geographically isolated wild boar population (sardinia, italy), which is classified, together with the corsican population, as a separate subspecies (sus scrofa meridionalis). two hundred and ten wild boars collected across sardinia were analysed with a set of 10 microsatellites and compared with 296 reference genotypes from continental wild popul ... | 2010 | 21179064 |
| effects of an alpha-4 integrin inhibitor on restenosis in a new porcine model combining endothelial denudation and stent placement. | restenosis remains the main complication of balloon angioplasty and/or stent implantation. preclinical testing of new pharmacologic agents preventing restenosis largely rely on porcine models, where restenosis is assessed after endothelial abrasion of the arterial wall or stent implantation. we combined endothelial cell denudation and implantation of stents to develop a new clinically relevant porcine model of restenosis, and used this model to determine the effects of an α4 integrin inhibitor, ... | 2010 | 21179441 |
| irreversible electroporation in a swine lung model. | this study was designed to evaluate the safety and tissue effects of ire in a swine lung model. | 2010 | 21191587 |
| single-port laparoscopic cholecystectomy with the x-cone: a feasibility study in 9 pigs. | virtually any port system for single-port laparoscopic surgery is for single usage only. the aim of this study was to trial the novel and completely reusable port x-cone in order to perform a cholecystectomy by one infraumbilical incision. | 2010 | 21193478 |
| scanning electron microscopy analysis of luminal inflammation induced by different types of coronary stent in an animal model. | there is histological evidence that drug-eluting stents are associated with delayed endothelialization and a persistent inflammatory state. moreover, clusters of inflammatory cells have been observed on luminal surfaces by scanning electron microscopy. with the aim of quantifying this inflammatory response, we implanted one bare-metal stent and two drug-eluting stents containing different doses of vinblastine embedded in the same polymer into the coronary arteries of 12 domestic pigs. the densit ... | 2010 | 21195533 |
| infrared skin damage thresholds from 1940-nm continuous-wave laser exposures. | a series of experiments are conducted in vivo using yucatan mini-pigs (sus scrofa domestica) to determine thermal damage thresholds to the skin from 1940-nm continuous-wave thulium fiber laser irradiation. experiments employ exposure durations from 10 ms to 10 s and beam diameters of approximately 4.8 to 18 mm. thermal imagery data provide a time-dependent surface temperature response from the laser. a damage endpoint of minimally visible effect is employed to determine threshold for damage at 1 ... | 2010 | 21198172 |
| comparison of electrocardiographic recordings in open-chest and closed-chest swine models. | the aim of our study was to compare the electrocardiographic recordings in an experimental open-chest swine model before and after left-sided thoracotomy to detect any surgery-induced fluctuations that might interfere with subsequent experimental interventions. we obtained electrocardiograms from 8 deeply anesthetized domestic swine and compared the respective st-segment potentials obtained after vascular surgery and after left-sided thoracotomy and dissection of the left anterior descending cor ... | 2010 | 21205452 |
| genetic characterization of african swine fever viruses from a 2008 outbreak in tanzania. | outbreaks of african swine fever (asf) have been reported in the past from several countries in sub-saharan africa. the aim of this study was to genotype asf viruses (asfvs) from the 2008 outbreak in morogoro and dar es salaam regions of tanzania. tissue samples from domestic pigs that died as a result of severe haemorrhagic disease were collected and analysed with pcr and genome sequencing methods using asfv-specific primer sets. nucleotide sequence data were obtained for the b646l (p72), e183l ... | 2010 | 21214868 |
| pathomorphological changes after radiofrequency ablation in the liver. | radiofrequency ablation (rfa) has become a widespread treatment option for liver carcinoma. there is limited knowledge regarding the macroscopic and histomorphological changes of induced lesions. twelve domestic pigs underwent rfa using a starburst xl device with ablation diameter of 3 cm. one animal died within 24 h, two animals were killed after 2 weeks, and nine after 4 weeks. their livers were used for macroscopic and histological investigation. six human liver resection specimens after prev ... | 2010 | 20403040 |
| patterns of east asian pig domestication, migration, and turnover revealed by modern and ancient dna. | the establishment of agricultural economies based upon domestic animals began independently in many parts of the world and led to both increases in human population size and the migration of people carrying domestic plants and animals. the precise circumstances of the earliest phases of these events remain mysterious given their antiquity and the fact that subsequent waves of migrants have often replaced the first. through the use of more than 1,500 modern (including 151 previously uncharacteriz ... | 2010 | 20404179 |
| light microscopic, electron microscopic, and immunohistochemical comparison of bama minipig (sus scrofa domestica) and human skin. | here we sought to evaluate the possibility of using chinese bama miniature pig skin as a suitable animal model for human skin. morphologic features of the skin of bama miniature pigs resemble those of human skin, including skin layer thickness, development of a superficial vascular system, structure of the dermal-epidermal interface, and extracellular matrix. the characteristics and densities of langerhans cells, fibroblasts, vascular endothelial cells, and mast cells were similar between bama p ... | 2010 | 20412690 |
| influence of the lung mechanical ventilation with injurious parameters on 7-ketocholesterol synthesis in sus scrofa. | the aim of work was to investigate changes of 7-ketocholesterol synthesis in alveolar macrophages in the dynamic of lung mechanical ventilation with injurious parameters. the goal of in vitro part of work was to observe influence of 7-ketocholesterol on inos and mip1 beta production in bronchoalveolar lavage fluid (balf) cells. we used 17 healthy domestic pigs randomly assigned into two treatment groups: group i with mechanical ventilation with physiological parameters; group || underwent injuri ... | 2010 | 20423610 |
| temporal distribution of ten calyptrate dipteran species of medicolegal importance in rio de janeiro, brazil. | brazilian studies involving entomological succession patterns in carcasses have been used to describe the necrophagous entomofauna of a determined municipality or region with forensic objectives. following the same objectives, an ecological study with 10 calyptrate dipterans was carried out during the winter of 2007 and the summer of 2008 in the metropolitan region of the municipality of rio de janeiro. the aim of this study was to describe several aspects of the phenology of these species in th ... | 2010 | 20428680 |
| correlation of right ventricular dysfunction parameters and pulmonary vascular obstruction score in acute pulmonary embolism in a porcine model. | this paper aims to non-invasively determine right ventricular dysfunction parameters (rvdp) in acute pulmonary embolism (ape) and to correlate these parameters with a computed tomography (ct)-based pulmonary artery obstruction score (os). in seven domestic pigs, magnetic resonance imaging (mri) was performed before (n = 7) and after (n = 5) ape was induced. analysis of relative changes in right ventricular stroke volume (rvsv%), output (rvo%), end-systolic (rvesv%), end-diastolic volume (rvedv%) ... | 2010 | 20428913 |
| endoscopic mucosal resection using a grasp-and-snare technique. | endoscopic mucosal resection (emr) is a minimally invasive method for en bloc removal of superficial gastrointestinal lesions. the aim of this study was to evaluate the feasibility of a novel grasp-and-snare emr technique. | 2010 | 20432205 |
| diffuse reflectance spectroscopy for optical soft tissue differentiation as remote feedback control for tissue-specific laser surgery. | laser surgery does not provide haptic feedback for operating layer-by-layer and thereby preserving vulnerable anatomical structures like nerve tissue or blood vessels. diffuse reflectance spectra can facilitate remote optical tissue differentiation. it is the aim of the study to use this technique on soft tissue samples, to set a technological basis for a remote optical feedback system for tissue-specific laser surgery. | 2010 | 20432281 |
| a study of alternative splicing in the pig. | abstract: | 2010 | 20444244 |
| variation of aujeszky's disease viruses in wild swine in usa. | in the united states of america, aujeszky's disease (pseudorabies) has been eradicated from all domestic swine. some re-emergence of infection occurred as vaccine use diminished. sporadic outbreaks have also occurred because of the reservoir of infection in feral swine that have spread across the southern two-thirds of the country and hawaii. in order to be able to understand the origins of re-emerging virus, sequence analysis of variable genes in pseudorabies virus (prv) has been used to differ ... | 2010 | 20444559 |
| pure "cable-tie partial nephrectomy": a porcine model. | the standard surgical procedure for polar renal tumors is nephron-sparing surgery, currently performed laparoscopically in most cases. this technically challenging surgery involves clamping of the hilar vessels and warm kidney ischemia. this study tested the feasibility of performing polar nephrectomy using a cable tie without hilar clamping or any other hemostatic procedure. | 2010 | 20445994 |
| transgastric endoluminal gastrojejunostomy: technical development from bench to animal study (with video). | gastrojejunal anastomosis is commonly performed for palliative management of malignant gastric outlet obstruction and bariatric surgery. natural orifice transluminal endoscopic surgery revolutionized the surgical approach to intra-abdominal surgery. this study explored the possibility of performing gastrojejunostomy (gj) by using a hybrid natural orifice transluminal endoscopic surgery approach. | 2010 | 20004893 |
| detection of hepatitis e virus in samples of animal origin collected in hungary. | hepatitis e virus (hev) is an enterically transmitted human pathogen. hev infections are mainly associated with acute, self-limited, icteric hepatitis with an average mortality rate of 1%. animal reservoirs are considered to play an important role in the maintenance of the virus and in the spread of hev to humans. hev-induced seroconversion was described in several species, however clinical hepatitis in animals has not been observed to date. hev strains from animals are genetically closely relat ... | 2010 | 20005644 |
| impact of contrast material volume on quantitative assessment of reperfused acute myocardial infarction using delayed-enhancement 64-slice ct: experience in a porcine model. | our purpose in this study was to compare the impact of contrast material volume in delayed-enhancement computer tomography (ct) imaging for assessing acute reperfused myocardial infarction. | 2010 | 20017004 |
| tylosin and chlorotetracycline decrease the duration of fecal shedding of e. coli o157:h7 by swine. | previously we have shown that experimentally infected swine, fed an antibiotic-free diet, can become colonized and shed escherichia coli o157:h7 for at least 2 months. however, in epidemiological studies this organism is only rarely recovered from domestic swine and the basis for this discrepancy is not clear. in this report we demonstrate that significantly fewer pigs fed diets containing subtherapeutic levels of either tylosin or chlorotetracycline shed e. coli o157:h7 for longer than 2 weeks ... | 2010 | 20018464 |
| nanofiber micro-dispersed oxidized cellulose as a carrier for topical antimicrobials: first experience. | micro-dispersed oxidized cellulose, already used for hemostasis, might be helpful for introduction of an antimicrobial drug. | 2010 | 20163259 |
| next generation biodegradable ureteral stent in a yucatan pig model. | ureteral stents are commonly used to facilitate kidney drainage but they may produce significant stent symptoms and morbidity, and require a secondary procedure for removal. previous biodegradable stents showed bio-incompatibility or inconsistent degradation, requiring extra procedures to remove undegraded stent fragments. we previously reported a first generation biodegradable stent composed of suture-like material that required placement through the lumen of a sheath and degraded by 10 weeks. ... | 2010 | 20022028 |
| a diet supplemented with l-carnitine improves the sperm quality of piétrain but not of duroc and large white boars when photoperiod and temperature increase. | it has been reported that a diet supplemented with l-carnitine can improve sperm quality in some mammalian species. against this background, the current study seeks to determine the effects of feeding l-carnitine (625 mg day(-1)) on boar semen characteristics (ejaculate volume, sperm concentration, sperm viability, acrosome and mitochondrial sheath integrity, sperm motility, sperm morphology, and osmotic resistance of spermatozoa) in three different porcine breeds (sus domesticus) (piétrain, dur ... | 2010 | 20022096 |
| human perception of vocalizations of domestic piglets and modulation by experience with domestic pigs (sus scrofa). | interspecific communication between humans and pets is possible through vocal cues. we studied how humans with differing experience with domestic pigs (sus scrofa) interpret pig vocalizations. forty-eight ethologists studying pigs, 31 pig-caretakers and 54 naive students evaluated the emotional intensity and valence (negative/positive) of recordings from two negative (castration, isolation) and two positive (reunion with the sow, postsuckling) contexts. they also identified the context in which ... | 2010 | 20175599 |
| cranial muscles of the sulawesi babirusa (babyrousa celebensis). | the detailed muscular anatomy of the head of the sulawesi babirusa (babyrousa celebensis) is described for the first time. the results show that the muscular anatomy of the babyrousa is very similar to the pig genus sus, despite long geological separation from it. some differences were noted: the m. parietoauricularis was more clearly separated into two parts in the babirusa than in the domestic pig; the rostral fibres of the m. levator anguli oculi reached the infraorbital sinus in the babirusa ... | 2010 | 20028377 |
| reduced l-type calcium current in ventricular myocytes from pigs with hyperdynamic septic shock. | to hypothesize that reduced l-type calcium current with consequent shortening of cardiac repolarization is present in a clinically relevant porcine model of hyperdynamic septic shock. myocardial depression is a well-recognized manifestation of sepsis and septic shock. reduction of l-type calcium current was demonstrated to contribute to the myocardial depression in endotoxemic rodents. | 2010 | 20029342 |
| porcine torque teno virus: determination of viral genomic loads by genogroup-specific multiplex rt-pcr, detection of frequent multiple infections with genogroups 1 or 2, and establishment of viral full-length sequences. | torque teno virus (ttv) is a non-enveloped virus with a circular, single-stranded dna genome. ttv is currently classified in the unassigned genus anellovirus, and distinct ttvs of tentative species-status infect a wide range of vertebrates. in domestic pigs and wild boars, porcine ttv occurs in two genogroups, ttv1 and ttv2, which are currently detected using only conventional pcr assays. to allow high-throughput testing, the present study describes development of a multiplex real-time (rt)-pcr ... | 2010 | 20031342 |
| long-term shedding of hepatitis e virus in the feces of pigs infected naturally, born to sows with and without maternal antibodies. | pigs are presumed reservoirs for hepatitis e virus (hev) transmission to humans. to examine infection kinetics, two litters of domestic pigs (a and b, each containing 10 piglets) infected naturally with hev were studied until pigs were 6 months old. maternal igg and iga antibodies were detected in litter a piglets, but not in litter b ones. all pigs shed hev in feces when they were 30-110 days old, and 17 developed viremia at 40-100 days of age. phylogenetic analysis revealed a highly close sequ ... | 2010 | 19950246 |
| survival and neurological outcomes after nasopharyngeal cooling or peripheral vein cold saline infusion initiated during cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest. | we have previously demonstrated that nasopharyngeal cooling initiated during cardiopulmonary resuscitation improves the success of resuscitation. in this study, we compared the effects of nasopharyngeal cooling with cold saline infusion initiated during cardiopulmonary resuscitation on resuscitation outcome in a porcine model of prolonged cardiac arrest. we hypothesized that nasopharyngeal cooling initiated during cardiopulmonary resuscitation would yield better resuscitation outcome when compar ... | 2010 | 20081534 |
| european wild boars and domestic pigs display different polymorphic patterns in the toll-like receptor (tlr) 1, tlr2, and tlr6 genes. | during the last decade, the toll-like receptors (tlrs) have been extensively studied, and their immense importance in innate immunity is now being unveiled. here, we report pronounced differences--probably reflecting the domestication process and differences in selective pressure--between wild boars and domestic pigs regarding single nucleotide polymorphisms (snps) in tlr genes. the open reading frames of tlr1, tlr2, and tlr6 were sequenced in 25 wild boars, representing three populations, and i ... | 2010 | 19953243 |
| high prevalence of anti-trichinella igg in domestic pigs of the son la province, vietnam. | although several outbreaks of trichinella infection among humans have occurred in northwestern vietnam, no information is available on the circulation of trichinella among domestic pigs. the objective of the present study was to estimate the seroprevalence of anti-trichinella igg in free-roaming pigs (sus scrofa) in the son la province of northwestern vietnam, where a human outbreak of trichinellosis occurred in june 2008. serum samples were collected from free-roaming pigs of four communes of t ... | 2010 | 19962244 |
| synthetic atrial natriuretic peptide improves systemic and splanchnic circulation and has a lung-protective effect during endotoxemia in pigs. | pharmacological blockade of the renin-angiotensin system is thought to maintain gut perfusion during circulatory stress and thereby avoid later failure of distant organs. in this controlled experimental study, we investigated the effects of carperitide, a synthetic atrial natriuretic peptide that inhibits the renin-angiotensin system, on the systemic and splanchnic circulation during fluid-resuscitated endotoxemia in pigs. | 2010 | 19933537 |
| incidence, diversity, and molecular epidemiology of sapoviruses in swine across europe. | porcine sapovirus is an enteric calicivirus in domestic pigs that belongs to the family caliciviridae. some porcine sapoviruses are genetically related to human caliciviruses, which has raised public health concerns over animal reservoirs and the potential cross-species transmission of sapoviruses. we report on the incidence, genetic diversity, and molecular epidemiology of sapoviruses detected in domestic pigs in a comprehensive study conducted in six european countries (denmark, finland, hunga ... | 2010 | 19940055 |
| histomorphologic and ultrastructural lesions of the pancreas in a porcine model of intra-abdominal hypertension. | intra-abdominal hypertension (iah) and abdominal compartment syndrome are increasingly observed in patients with severe acute pancreatitis (sap). the aim of this study was to investigate the effects of iah on pancreatic histology and ultrastructure in a porcine model. we examined 16 intubated and anesthetized domestic pigs with a mean body weight of 50.6 (sd, 3.8) kg. using a co2 pneumoperitoneum, the intra-abdominal pressure was increased to 30 mmhg for an investigation period of 6 or 12 h (eac ... | 2010 | 19940813 |
| a comparison of intracardiac and transesophageal echocardiography to detect left atrial appendage thrombus in a swine model. | transesophageal echocardiography (tee) is the gold standard in the evaluation for left atrial appendage (laa) thrombus in patients with atrial fibrillation (af) and is often performed prior to af ablation. we routinely use intracardiac echocardiography (ice) to assist in af ablation; however, standard right atrial views do not provide adequate visualization of the laa. as the incidence of thrombus in this population is relatively low, tee incurs additional risk, cost, and patient discomfort. nov ... | 2010 | 19943097 |
| correlation between clinico-pathological outcome and typing of haemophilus parasuis field strains. | haemophilus parasuis is the etiologic agent of glässer's disease in pigs, which is pathologically characterized by serofibrinous polyserositis and arthritis. h. parasuis include virulent and non-virulent strains and confirmation of virulence in h. parasuis is still dependent on experimental reproduction of the disease. since the variability in virulence is supported by serotyping and genotyping (particularly, multilocus sequence typing [mlst]), we examined the relationship between the classifica ... | 2010 | 19945233 |
| detection of a novel hepatitis e-like virus in faeces of wild rats using a nested broad-spectrum rt-pcr. | hepatitis e is a rare human disease in developed countries. it is caused by hepatitis e virus (hev), which is probably transmitted zoonotically to humans from domestic pigs and wild boars. multiple reports on the detection of hev-specific antibodies in rats have suggested the presence of an hev-related agent; however, infectious virus or a viral genome has not been demonstrated so far. here, a nested broad-spectrum rt-pcr protocol was developed capable of detecting different hev types including ... | 2010 | 19889929 |
| characterisation of experimental infections of domestic pigs with genotype 2.1 and 3.3 isolates of classical swine fever virus. | the early identification of classical swine fever epizootics is hampered by difficulties in recognising early signs of infection, due to a lack of specific clinical signs. in addition many textbook descriptions of csf are based on observations of disease caused by historic, mainly genotype 1, strains. our objective was to improve our knowledge of the diverse range of signs that different csfv strains can cause by characterising the experimental infection of domestic pigs with both a recent strai ... | 2010 | 19875252 |
| interferon-gamma induction correlates with protection by dna vaccine expressing e2 glycoprotein against classical swine fever virus infection in domestic pigs. | classical swine fever (csf) is a highly contagious viral infection affecting domestic and wild pigs. for classical swine fever virus (csfv), immunization with plasmids expressing different versions of glycoprotein e2 has proven an effective way to induce protection. previously, we have also shown that immunization with dna vaccine expressing glycoprotein e2 (dna-e2) induced specific t helper cell responses in the absence of neutralizing antibodies. however, the role of t cell responses in protec ... | 2010 | 19896784 |
| multiple asian pig origins revealed through genomic analyses. | previous mitochondrial dna (mtdna) studies have suggested that european and asian pig populations were derived through multiple domestication events. we investigated whether domestic pig populations were derived from distinct ancestors within their respective regions, using eight domestic breeds (five european and three asian), and also european and asian wild boar populations. genomic analyses utilized 21 microsatellite markers (ms) selected for their distribution across the pig genome in addit ... | 2010 | 19900568 |
| early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney. | atherosclerotic renal artery stenosis (aras) is increasingly identified in patients with end-stage renal disease. renal function in aras patients deteriorates more frequently than in nonatherosclerotic renal artery stenosis (ras). this study was designed to test the hypothesis that atherosclerosis modifies the relationship between single-kidney hemodynamics and function and the severity of stenosis. the degree of unilateral ras in domestic pigs (4 normal, 26 ras, and 22 aras) was correlated with ... | 2010 | 20462971 |
| epidemiological survey of trichinellosis in wild boar (sus scrofa) and fox (vulpes vulpes) in a french insular region, corsica. | the mediterranean island of corsica was considered trichinella-free until 2004, when t. britovi larvae were discovered in domestic pigs at meat inspection. one red fox was also found infected the same year and in the same area than the infected pigs. this last finding highlighted the presence of trichinellosis in corsican wildlife. a trichinella survey was thus performed in wild boar (sus scrofa) and fox (vulpes vulpes), the two large wild species present on the island, to determine prevalence o ... | 2010 | 20471753 |
| experimental infection of pigs with border disease virus isolated from pyrenean chamois (rupicapra pyrenaica). | between 2001 and 2007, several outbreaks of disease associated with border disease virus (bdv) infection were reported in the central pyrenees (northeast spain) and were associated with a major reduction in chamois (rupicapra pyrenaica) populations. at the same time, wild boars (sus scrofa) from the same area were found to be seropositive to this pestivirus, without showing clinical signs. the present study examines the susceptibility of domestic swine and the course of the infection with a bdv ... | 2010 | 20453208 |
| detection of porcine circovirus in rodents - short communication. | porcine circoviruses (pcv) are present worldwide, infecting domestic pigs and wild boars alike. studies under laboratory conditions indicated that pcv can be taken up by mice and the virus can replicate in these animals. the possible role of rodents in maintaining and transmitting pcv2 infection in the field has not been investigated yet. the present study reports the detection of pcv2, the pathogenic form of the virus, in mice and rats. a number of rodents, such as mice, rats and voles, were co ... | 2010 | 20460225 |
| dietary consistency and the midline sutures in growing pigs. | the purpose of this study was to investigate the effects of reduced masticatory function on midline suture growth and morphology in growing pigs. | 2010 | 20477970 |
| [hepatitis e--a new zoonotic disease in germany?]. | hepatitis e virus (hev) is the most frequent pathogen of a fecal-oral transmitted hepatitis in humans in many developing countries. it is endemic in the middle east, in india, in southeast asia, central asia as well as in central and south america. it can be predominantly found in young adults. the mortality rate comes up to 2% whereas in pregnant women death rate can reach about 25%. until a few years ago, acute hepatitis e was thought to be rare in industrialized countries: most cases were fou ... | 2010 | 20496825 |
| an animal model for sinus floor elevation with great elevation heights. macroscopic, microscopic, radiological and micro-ct analysis: ex vivo. | different animal models are used for research and training concerning sinus floor elevation. however, there is little information regarding an animal model for elevation heights of approximately 10 mm. the aim of this study was to explore the anatomical aspects of the maxillary sinus of adult pigs and to investigate the suitability of this animal as a model for sinus floor elevation training and research with great elevation heights. | 2010 | 20497438 |
| cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: implications for clinical trials. | abstract : introduction : early randomized clinical trials of autologous bone marrow cardiac stem cell therapy have reported contradictory results highlighting the need for a better evaluation of protocol designs. this study was designed to quantify and compare whole body and heart cell distribution after intracoronary or peripheral intravenous injection of autologous bone marrow mononuclear cells in a porcine acute myocardial infarction model with late reperfusion. methods : myocardial infarcti ... | 2010 | 20504285 |