Publications

haemodynamic changes after spinal cord transection are anaesthetic agent dependent.	1 to evaluate the effect of high spinal cord transection (sct), between t4 and t5, on the mean arterial pressure (map) and heart rate in animals anaesthetized with different anaesthetic agents: ether (n = 12), 20% urethane, 1.2 g kg(-1) (n = 12), 2% tri-bromide-ethanol, 200 mg kg(-1) (n = 12); chloral hydrate and urethane, 75 and 525 mg kg(-1) respectively (n = 12). 2 in the animals anaesthetized with ether or urethane, sct caused an immediate major drop in map, with hypotension and bradycardia ...	2007	18076477
sentinel lymph node biopsy in squamous cell carcinoma of the head and neck: where we stand now, and where we are going.	this review was performed to evaluate the existing literature on sentinel lymph node biopsy (slnb) for early-stage oral and oropharyngeal head and neck squamous cell carcinoma (hnscc) in clinically negative (n0) necks.	2007	18076844
real-time observation of bacteriophage t4 gp41 helicase reveals an unwinding mechanism.	helicases are enzymes that couple atp hydrolysis to the unwinding of double-stranded (ds) nucleic acids. the bacteriophage t4 helicase (gp41) is a hexameric helicase that promotes dna replication within a highly coordinated protein complex termed the replisome. despite recent progress, the gp41 unwinding mechanism and regulatory interactions within the replisome remain unclear. here we use a single tethered dna hairpin as a real-time reporter of gp41-mediated dsdna unwinding and single-stranded ...	2007	18077411
[a case of thoracic esophageal cancer with invasion of the main bronchus in which long-term survival with high quality of life was achieved through chemoradiotherapy, esophageal bypass and then additional chemotherapy].	we administered chemoradiotherapy consisting of 5-fluorouracil and cisplatin combined with radiation (59.8 gy) to a patient with locally advanced esophageal cancer (t4 (left main bronchus) n2m0, stage iva). the cancer disappeared completely after the chemoradiotherapy. however, because an esophagobronchial fistula occurred, an esophageal bypass was performed according to the method of postlethwait. thereafter, multiple lung metastases appeared, which we treated with paclitaxel 120-210 mg/body du ...	2007	18079631
repair of an infrarenal abdominal aortic aneurysm is associated with persistent left ventricular diastolic dysfunction.	left ventricular (lv) diastolic function has received much attention recently. however, few studies have evaluated lv diastolic function in the perioperative period. the aim of this study was to elucidate perioperative changes in diastolic function using tissue doppler imaging (tdi) in patients undergoing repair of an infrarenal abdominal aortic aneurysm (aaa).	2007	18084132
effects of concanavalin a on intestinal brush border enzyme activity in broiler chickens.	1. the effects of concanavalin a (con a) on enzymes from the intestinal brush border were studied using membrane vesicles (bbmv) prepared from 3- and 6-week-old broiler chickens. 2. maltase, sucrase, phytase, alkaline phosphatase and leucine aminopeptidase activities were assayed in bbmv in the absence (t0) or presence (t1) of con a, or in the presence of casein (t2). disaccharidase specific activities were assayed in the presence of con a that had been pre-incubated with the enzyme (t3) or with ...	2007	18085452
impaired immune responses in tuberculosis patients are related to weight loss that coexists with an immunoendocrine imbalance.	the study's objective was to examine whether factors related to the host status may bear some relation with the profile of the immune response displayed by tuberculosis (tb) patients. the in vitro immune response (antigen-driven lymphoproliferation and cytokine production) and the presence of alcoholism or disease-related factors, like heart and respiratory rates, and weight loss (body mass index, bmi) were investigated in 31 males with active, untreated tb. compared to 16 age-matched healthy ma ...	2007	18073514
the continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?	advances in genomics have led to mounting expectations in regard to their impact on health care and disease prevention. in light of this fact, a comprehensive research agenda is needed to move human genome discoveries into health practice in a way that maximizes health benefits and minimizes harm to individuals and populations. we present a framework for the continuum of multidisciplinary translation research that builds on previous characterization efforts in genomics and other areas in health ...	2007	18073579
transoral laser microsurgery for advanced laryngeal cancer.	to report the oncologic and functional outcomes of transoral laser microsurgery (tlm) in the treatment of advanced laryngeal cancer.	2007	18086960
validation of the proposed international association for the study of lung cancer non-small cell lung cancer staging system revisions for advanced bronchioloalveolar carcinoma using data from the california cancer registry.	recently, the international association for the study of lung cancer (iaslc) has proposed significant modifications to the existing tnm and stage grouping classifications affecting the t4 and m descriptors. we set out to validate this staging system for bronchioloalveolar carcinoma (bac) cases using data from the california cancer registry (ccr).	2007	18090578
a retrospective study of definitive chemoradiotherapy for elderly patients with esophageal cancer.	the efficacy and safety of definitive chemoradiotherapy (crt) for elderly patients with esophageal cancer have not been fully elucidated yet. we conducted a retrospective comparison of the outcomes of crt between elderly and nonelderly patients with stage ii-iii (non-t4) esophageal cancer.	2007	18091055
radiotherapy for squamous cell carcinoma of the nasal vestibule.	to evaluate the efficacy of radiotherapy (rt) alone or combined with surgery for the treatment of the nasal vestibule squamous cell carcinomas.	2007	18091056
measuring tissue perfusion during pressure relief maneuvers: insights into preventing pressure ulcers.	to study the effect on tissue perfusion of relieving interface pressure using standard wheelchair pushups compared with a mechanical automated dynamic pressure relief system.	2007	18092567
identification of host range mutants of myxoma virus with altered oncolytic potential in human glioma cells.	the authors have recently demonstrated that wild-type myxoma virus (mv) tagged with gfp (vmyxgfp) can generate a tumor-specific infection that productively infects and clears human tumor-derived xenografts when injected intratumorally into human gliomas transplanted into immunodeficient mice (lun et al, 2005). to expand the understanding of mv tropism in cancer cells from a specific tissue lineage, the authors have screened a series of human glioma cells (u87, u118, u251, u343, u373) for myxoma ...	2007	18097886
[treatment of rectal cancer by laparoscopie].	initiated later than for colon cancer, the evaluation of the use of laparoscopy in rectal cancer is still ongoing. data on its feasibility and clinical tolerance are available. evaluation has been based on better vision of total mesorectal excision down to the pelvic floor with laparoscopy. laparoscopy may be recommended as standard practice except in the case of t4 tumours, recurrences and after certain former colorectal procedures. the conversion rate decreases with the acquisition of experien ...	2007	18156113
[bone mineral density of children and adolescents with congenital hypothyroidism].	a cross sectional study was made on 60 patients (9.9 +/- 1.8 yr-old) with congenital hypothyroidism (ch) (group a): 40 girls (23 prepubertal) and 20 boys (18 prepubertal). control group (group b) was constituted of 28 healthy children (10.4 +/- 2.1 yr-old): 18 girls (8 prepubertal) and 10 boys (9 prepubertal). aims: to evaluate bone mineral density (bmd) and content (bmc) and to correlate them with chronological and bone age (ba), sex, sexual maturation, l-t4 dose, tsh, tt4, ft4, and ch etiology ...	2007	18157383
primary malignant melanoma of the female urethra.	a case of primary urethral malignant melanoma of a 69-year-old japanese woman is presented. a hemorrhagic tumor measuring 1 cm in diameter was diagnosed by the stamp method. clinically, the primary lesion was a t4 tumor infiltrating to the bladder neck, vagina, and vulva. computed tomography did not detect any inguinal lymph node swelling or metastases to other sites. we selected radical extirpation, including cystectomy, ureterostomy, and bilateral inguinal and pelvic lymph node dissection. alt ...	2007	18158055
role of fdg-pet in the assessment of survival prognosis in melanoma.	positron-emission tomography (pet) employing fluorodeoxyglucose (fdg) has proven to be a highly sensitive and specific diagnostic method in the staging and restaging of various neoplasms, including melanoma, complementing morphologic imaging. fdg uptake has been correlated with proliferation rate, and thus, the degree of malignancy of a given tumor (i.e., grading). consecutively, a relationship of survival prognosis and the extent of tumor burden as well as degree of fdg accumulation--determined ...	2007	18158764
current status of adjuvant therapy for colon cancer.	due to its frequency and persistently high mortality, colorectal cancer represents a major public health problem. the use of adjuvant chemotherapy has improved prognosis in stage iii disease, but much work remains to be done in optimizing adjuvant treatment, including refinement of ability to predict disease course and response to chemotherapy. the folfox4 regimen is now considered standard treatment for stage iii disease. combinations of irinotecan and 5-fluorouracil (5-fu) have not proven to b ...	2007	19262714
potential benefits of integration of therapies with chemoradiation in rectal cancer.	improved pelvic control with reduced toxicity and enhanced sphincter preservation has been demonstrated with neoadjuvant chemoradiation compared with postoperative adjuvant chemoradiation in patients with stage ii and iii rectal cancer. however, analyses from many trials of adjuvant chemoradiation indicate that patients with t3 node-positive and t4 tumors are at high risk of pelvic recurrence even with use of chemoradiation. this limitation could be addressed with treatment intensification strat ...	2007	19360153
advances in cd4 cell enumeration in resource-poor countries.	to review recent progress in the development and evaluation of rapid cd4 cell assays needed to treat hiv-infected individuals in resource-poor countries.	2007	19372892
[toxic nodular goiter].	to date no study in our country was specifically dedicated on toxic nodular goiter. they were just mentioned in generally studies about hyperthyroidism.	2007	19102108
the confine-and-release method: obtaining correct binding free energies in the presence of protein conformational change.	free energy calculations are increasingly being used to estimate absolute and relative binding free energies of ligands to proteins. however, computed free energies often appear to depend on the initial protein conformation, indicating incomplete sampling. this is especially true when proteins can change conformation on ligand binding, as free energies associated with these conformational changes are either ignored or assumed to be included by virtue of the sampling performed in the calculation. ...	2007	18843379
an investigation on the germination of seeds of kwao kreu kao (pueraria candollei grah. ex benth) as affected by both water soakings and hot air oven treatments.	this experiment was carried out at the faculty of technology, mahasarakham university, mahasarakham 4400, thailand to investigate effects of different water-soaking durations and hot air oven treatments on the germination of seeds of kwao kreu kao (pueraria candollei grah. ex benth) plants. the experiment was laid in a randomised complete block design with four replications. the results showed that after tested for electrical conductivity (ec) values for cracking of seeds, all seeds being used w ...	2007	19086573
response of rice advance line pb-95 to potassium application in saline-sodic soil.	a field experiment was conducted to evaluate the response of rice crop to potassium fertilization in saline-sodic soil during 2005. soil samples were collected before transplanting of rice crop and analysed for physical and chemical properties of the soil. in this experiment five rates of k2o (0, 25, 50, 75 and 100 kg ha(-1)) were applied in the presence of basal doses of n and p2o5 i.e., 110 and 90 kg ha(-1), respectively. whole of p, k and 1/2 of n were applied at the time of rice transplantin ...	2007	19090203
effect of marble industry effluent on seed germination, post germinative growth and productivity of zea mays l.	a green house study was conducted at the university of malakand, nwfp, pakistan to evaluate the effect of marble industry effluent on soil ph, germination, post germinative growth and productivity of maize. the experiment was conducted in triplicate form for each treatment and tape water was used as control (t0). effluents were diluted with tap water at concentration of 20% (t1), 40% (t2), 60% (t3), 80% (t4) and also used 100% (t5) concentration in 4 kg soil pot(-1) and plants were grown for 90 ...	2007	19090297
effect of chemical paclobutrazol on growth, yield and quality of okra (abelmoschus esculentus l.) har lium cultivar in northeast thailand.	this investigation was carried out at mahasarakham university experimental farm, mahasarakham university, northeast thailand in the late rainy season of the 2003 to 2004 with the use of roi-et soil series (oxic paleustults). the experiment aims to search for more information on the effect of different rates of chemical paclobutrazol (pbz) application on growth, yield and quality of edible okra pods. a randomised complete block design (rcdb) with four replications was used for the experiment. the ...	2007	19069514
body mass index and thyroid function in adolescent girls.	the present research was conduted to examine the relationship between thyroid function and body mass index. a cross-sectional study was carried out in lar province and its' vicinity in south of iran. by stepwise random sampling from all public girls' high schools, 227 high school participants (aged 12-21) were selected. serum samples were collected and assayed for triiodothyronine (t3), thyroxine (t4), thyroid stimulating hormone (tsh), reverse triiodothyronine (rt3), free thyroxine (ft4), free ...	2007	19069886
serum proteins and some biochemical parameters in broiler chickens fed with raw and treated bitter vetch (vicia ervilia) seeds.	this study carried out to evaluate the effect of bitter vetch seeds on serum proteins and biochemical parameters in broiler chickens. a total of 1320 one-day-old broiler chicks of a commercial breed were placed in 64 pens. treatments were included raw and four different processed bitter vetch seeds in three levels (150, 300 and 450 g kg(-1)) and a corn-soybean based diet as control. each treatment group consisted of four replicates. processing methods were included soaked in water for 12 h, auto ...	2007	19069902
effects of green manures on growth, yield and quality of green okra (abelmoschus esculentus l.) har lium cultivar.	this green manure experiment with the use of okra crop as indicator plant was carried out at mahasarakham university experimental farm, mahasarakham province, northeast thailand during may to september 2005 to investigate four types of green manure legume crops on growth, yield and quality of edible fresh pods of okra crop when grown on roi-et soil series (oxic paleustults). the four types of green manure plants include jack bean, cowpea, green gram, and giant sensitive plant. the experiment con ...	2007	19070046
initial results of retrospective study: preoperative transurethral excision plus chemotherapy and radiation therapy and trial of bladder preservation.	for patients with invasive bladder cancer the usual recommended treatment is radical cystectomy, although transurethral resection of the tumor, systemic chemotherapy, and radiotherapy are each effective in some patients. this retrospective study evaluated the experience of the clinical oncology department, tanta university hospital with combined modality treatment and selective bladder preservation in patients with muscle-invading bladder cancer with assessment of its safety, tolerance, and effi ...	2007	19034344
[triiodothyroacetic acid in euthyroid goiter. new data on its mechanisms of action. comparison with l-thyroxin].	euthyroid goiter is usually treated with ths-inhibiting doses of l-thyroxin (l-t4), which can have troublesome adverse effects. it has been suggested that triiodothyroacetic acid (triac), a tsh suppressor, might have fewer peripheral effects and better tolerability than t4. we therefore compared the risk-benefit ratios of the two drugs. thirty-six women with euthyroid goiter (no thyroid cancer) were randomized to receive either triac (19.6 ug/kg) (n=19) or l-t4 (1.7 ug/kg) (n=17) for 11 months. ...	2007	18666468
altered serum levels of thyroxine, triiodothyroinine and thyroid stimulating hormone in patients with depression.	to assess serum level of thyroxine (t4), triiodothyronine(t3) and thyroid stimulating hormone(tsh) in patient with depression.	2007	18604049
evaluation of the bard bta-test in the diagnosis of upper urinary tract tumours.	the bta-test is an agglutination assay that qualitatively detects the presence of complexes of basement membrane within the urine of patients with bladder cancer. however, the significance of bta test in other urotelial tumours has not been extensively studied. therefore, in the present research, we examined the validity of bta-test in patients suffering from ureteral or renal pelvis cancer, and compare results with urincitology. 35 patients were included in this study (13 with ureteral and 22 w ...	2007	18595223
chemotherapy by m-vac protocol in progressive bladder carcinoma treatment.	treatment of invasive bladder carcinoma is complex therapy procedure which means surgical and non-surgical treatment appliance. in spite of radical surgical treatment conduction, the gold standard in invasive bladder tumor therapy, about 30-40% patients spread metastasis in further disease course. the system chemotherapy in invasive bladder tumors treatments is marked with accent. its fundamental aim is to correct results of surgical treatment. this therapy option very often means the only modal ...	2007	18595238
[alterations of cell cycle regulating proteins: rb, p21 and p16 in laryngeal cancer].	in cell cycle, most of the regulatory actions occur at the so-called restriction point (r) in the late g1 phase. tumor suppressor genes; rb, p53 and p21 are among the most important of the agents suppressing transition through r point. changes in the expression of rb (retinoblastoma) gene correlate with the presence of rb protein and they are believed to be an early event in carcinogenesis. this issue seems to be not plainly defined in laryngeal cancer. p21 with p16, cyclin d1 and rb genes that ...	2007	18546941
thyroidectomy for graves' hyperthyroidism. retrospective study of patients' appreciation.	to retrospectively investigate the patients' views of surgical treatment of graves' hyperthyroidism.	2007	18338549
synthesis of hiv-1 psi-site rna sequences with site specific incorporation of the fluorescent base analog 2-aminopurine.	fluorescent nucleotide base analogs can serve as sensitive probes of the local structure and chemical environment of the base within a nucleic acid sequence. a significant strength of these base analogs is their similarity in molecular constitution and chemical properties to natural bases. while chemical synthesis has afforded the ability to generate oligonucleotides in good yield with sequence-specific incorporation of fluorescent base analogs, this method is limited in practice to the synthesi ...	2007	18431441
[prokaryotic expression of trichinella spiralis gene ts21 and identification of the recombinant protein].	to express the antigen gene ts21 of trichinella spiralis, purify the recombinant protein and test its antigenicity.	2007	18441887
clinical effects of leukofiltration and surface modification on post-cardiopulmonary bypass atrial fibrillation in different risk cohorts.	a manifestation of inflammatory injury to the heart, atrial fibrillation (af), ranks among the most frequent and potentially life-threatening post-operative complications.	2007	18181517
serum tsh and total t4 in the united states population and their association with participant characteristics: national health and nutrition examination survey (nhanes 1999-2002).	describe thyrotropin (tsh) and thyroxine (t4) levels in the u.s. population and their association with selected participant characteristics.	2007	18177256
effect of different hormonal therapies on thyroid function in surgical menopause: short-term results.	to determine the effects of different hormone replacement therapy (hrt) regimens on thyroid function in surgical menopause.	2007	18210897
[a case of resection of esophageal cancer infiltrating the left main bronchus following preoperative chemo-radiotherapy and resection of metachronous lung metastasis].	we herein report a case of t4 esophageal carcinoma, which was resected after chemo-radiation therapy. in addition, the metachronous lung metastasis was also resected. a 59-year-old female with esophageal carcinoma, which invaded the left main bronchus, underwent chemo-radiation therapy (the combination of systemic chemotherapy of 5-fu/cddp and external radiation therapy) from january 2004. after the therapy, although the imaging showed a downstaging of esophageal carcinoma, a severe esophageal s ...	2007	18219866
[a clinical study of esophagectomy after chemo-radiation therapy for advanced esophageal carcinoma].	the aim of this study was to evaluate the efficacy of preoperative neoadjuvant therapy (nat) including chemo-radiation or radiation in patients with t3/t4 advanced esophageal squamous cell carcinoma. we reviewed 115 patients with t3/t4 tumors from january 1994 through august 2006. forty-seven patients received nat, and the remaining 68 patients had surgery alone. of these 47 patients, 14 patients underwent esophagectomy following nat, and 33 patients underwent consecutive chemoradiation. patient ...	2007	18219872
[three cases of unresectable advanced gastric cancer treated with s-1 based chemotherapy after surgical bypass].	case 1: the patient underwent gastrojejunostomy [t4 (pancreas), n2, p0, cy0] in april 2004, and then 23 courses of chemotherapy with s-1 + doc (40 mg/m2/day 1:3 w). then, the regimen was switched to cpt-11 because of a decreased efficacy of the treatment, and cpt-11 was continued for 10 courses. (the patient was alive for 36 months). case 2: the patient was treated with s-1 [t4 (pancreas), n3, p0, cy0] after surgical bypass in november 2004. after two courses of chemotherapy with s-1, 9 courses ...	2007	18219928
can impairments of thyroid function test affect prognosis in patients with respiratory failure?	thyroid function test (tft) impairments can be detected in extrathyroidal dysfunction, primarily in chronic obstructive pulmonary disease (copd) with acute respiratory failure (rf). the aims of this study were to: (i) evaluate tft impairments in patients with rf, (ii) compare tft results to a control group without rf and (iii) assess the effects of thyroid dysfunction on clinical outcome and prognosis of rf. the tft parameters were assessed in 65 patients (65.0 +/- 10.0 years, 49 males) with rf ...	2007	18224499
[surgical treatment in non-small cell lung cancer invading to the chest wall (t3) and vertebra (t4)].	the involvement of the chest wall (t3) or the vertebra (t4) in non-small cell lung cancer (nsclc) is seen at a ratio between 3-8% in patient's undergone surgery. the most important factors affecting the survival in both t3 and t4 tumors are the absence of lymph node invasion and a complete resection application. amount of 162 cases were subjected to operation due to nsclc between january 2004-july 2006. examined retrospectively, these cases were determined to be chest wall invasion in 12 (7.4%) ...	2007	18224507
measurement of the acute inflammatory response to walking exercise in copd: effects of pulmonary rehabilitation.	this pilot study concerns the evaluation of the acute cytokine response to exercise and changes in this throughout a 7 week pulmonary rehabilitation programme.	2007	18229573
subpial hemangiopericytoma with marked extramedullary growth: case report.	hemangiopericytomas, vascular tumors arising in soft tissue, are relatively rare in the central nervous system; they comprise less than 1% of all hemangiopericytomas. central nervous system hemangiopericytomas occur primarily in the epidural space of the brain and spinal cord. there are no previous reports of subpial, extramedullary growing central nervous system hemangiopericytomas.	2007	18162866
the effects of simvastatin and levothyroxine on intima-media thickness of the carotid artery in female normolipemic patients with subclinical hypothyroidism: a prospective, randomized-controlled study.	patients with subclinical hypothyroidism (sht) have an increased risk of developing atherosclerosis, probably related to dyslipidemia. we compared the effects of levothyroxine (l-t4) versus simvastatin treatment on carotid intima-media thickness (imt) and lipid profiles in patients with sht.	2007	18163011
a novel fusion gene, trim5-cyclophilin a in the pig-tailed macaque determines its susceptibility to hiv-1 infection.	in old world monkeys, the tripartite motif 5alpha (trim5alpha) protein confers resistance to hiv-1 infection following virus entry into host cells. however, the pig-tailed macaque (macaca nemestrina) is an exception and is susceptible to hiv-1 infection. this study dissects the molecular mechanism of the pig-tailed macaque's susceptibility to hiv-1 infection.	2007	18172386
endovascular exclusion of mycotic aortic aneurysm.	the presence of prohibitive risk may preclude usual surgical management. such was the case for a critically ill, 60-year-old woman who presented with concomitant, life-threatening conditions. the patient presented with acute central cord syndrome and lower-extremity paraplegia after completing a 6-week course of intravenous antibiotics for methicillin-sensitive staphylococcus aureus bacteremia and osteomyelitis of the thoracic spine. radiologic examination revealed bony destruction of thoracic v ...	2007	18172531
lymph node metastases of adenocarcinoma of the esophagus and esophagogastric junction.	esophageal adenocarcinoma is becoming an increasingly important problem. it has been the most rapidly increasing malignancy in western countries in the last decades, and its prognosis is poor. the aim of this study was to evaluate the relationship between tumor invasion depth and lymph node metastasis for adenocarcinoma of the esophagus and esophagogastric junction, and to analyze the impact of lymph node metastases on survival of the patients.	2007	18167216
pediatric thyroid testing issues.	thyroid problems are common in children. while serum thyroid function tests lead to an accurate diagnosis in most patients, unique patient situations can produce misleading results. total t4 measurements can incorrectly suggest hypothyroidism in congenital thyroid binding globulin (tbg) deficiency and hyperthyroidism in tbg excess, as seen in high estrogen states. free t4 (ft4) measurement techniques involve either physical separation of unbound thyroxine from serum binding proteins or estimatio ...	2007	18167471
the use of konjac glucomannan to lower serum thyroid hormones in hyperthyroidism.	patients with hyperthyroidism occasionally need rapid restoration to the euthyroid state. in view of the increased enterohepatic circulation of thyroxine (t4) and triiodothyronine (t3) in thyrotoxicosis, and metabolic effects of konjac glucomannan in gastrointestinal system, we aimed to determine the activity of glucomannan in treatment of hyperthyroidism.	2007	18187431
thyroid dysfunction in patients with down syndrome.	the close relationship between thyroid disorder and down syndrome (ds) had been widely reported in the literature. the aim of this study was to assess the prevalence rate and the pattern of thyroid dysfunction in ds in taiwan.	2007	18265539
iodine status among pregnant women in kuwait.	up to now, little has been known about iodine intake and the prevalence of iodine deficiency (id), if any, in kuwait. urinary iodine excretion (uie) and changes in thyroid function during pregnancy were thus evaluated.	2007	18250611
effects of ghrelin administration on endocrine and metabolic parameters in obese women with polycystic ovary syndrome.	the novel peptide ghrelin displays multiple endocrine and non-endocrine actions. its strong gh-releasing activity in humans has long been recognized. however, in obesity, ghrelin administration induces a blunted gh secretion, enhances glucose and reduces insulin levels. the effects of ghrelin administration have not been investigated in polycystic ovary syndrome (pcos), which can be associated with obesity, hyperinsulinism, and gh hyposecretion. leptin is a mediator for energy balance opposed to ...	2007	18250617
a case of thyrotropin-producing pituitary adenoma, accompanied by an increase in anti-thyrotropin receptor antibody after tumor resection.	we describe a rare, but interesting, case of tsh-producing adenoma (tshoma), accompanied by increases in both anti-tsh receptor antibody (trab) and thyroid-stimulating antibody (tsab) after tumor resection. a 21-yr-old woman was referred to our department for further evaluation of pituitary tumor. in a nearby hospital, she had been diagnosed as having pituitary tumor. her serum free t4, free t3, and tsh levels were all elevated concomitantly. on the basis of a diagnosis of pituitary adenoma with ...	2007	18250618
[determining the thyroid hormones t3 and t4 in the urine: an unreliable test for hypothyroidism].	a 24-year-old woman complained of tiredness, sensitivity to cold, and feelings of depression. a diagnosis of hypothyroidism based on decreased 24 h urinary t3 and t4 excretion was made, and she was treated with levothyroxin. no blood tests were done. she was referred with the question if she had other endocrine disorders. her periods were regular, and on physical examination no abnormalities except slight acne were found. similarly, hypothyroidism was diagnosed by decreased thyroid hormone excre ...	2007	18237046
[abuse of anabolic steroids and its impact on thyroid function].	the use of anabolic steroids to increase physical performance and for aesthetic ends has reached alarming indices in the last three decades. besides the desired actions, several collateral effects have been described in the literature, such as the development of some types of cancer, ginecomasty, peliosis hepatis, renal insufficiency, virilization, amongst others. the most proeminent effect on human thyroid function is the reduction of thyroxine binding globulin (tbg), with consequent reductions ...	2007	18209883
[mr-endoscopic us correlation for loco-regional staging of rectal carcinoma].	to correlate findings at high-resolution mr and endoscopic us (eus) for preoperative loco-regional staging of rectal carcinoma.	2007	18235347
[non-small cell lung cancer : the limits of surgical resection].	the international staging system for lung cancer actually subdivides patients in two subcategories, according to surgical resectability. theoretically the landmark is between stages iiia and iiib. non-resectability of t4 tumors is controversial. because technical advances in surgical techniques and perioperative care, several selected patients with mediastinal involvement (left atrium, great vessels, carina, spine) can be resected with encouraging long-term outcomes. published data on surgical t ...	2007	18235416
predicting intraoperative vertebral rotation in patients with scoliosis using posterior elements as anatomical landmarks.	a retrospective study.	2007	18245992
anterior approach to the cervicothoracic junction without sternotomy: a report of 37 cases.	description of a new anterior approach to the cervicothoracic junction and retrospective study of results.	2007	18246011
[a 20-year retrospective histoclinical analysis of parotid gland tumors in the ent department am in katowice].	salivary gland neoplasms represent the diverse group of tumours encountered by the head and neck surgeons.	2007	18260221
[larynx and hypopharynx cancer morbidity in west pomerania region in the years 1990-2000].	1413 patient (1236 males and 177 females) with cancer of larynx or hypopharynx were treated in the ent department of the pomeranian medical academy in szczecin from 1990 to 2000. the patients were aged between 26 and 87 years. in the paper, based on the review of the cases history the following aspects have been determinated: incidence rate of the laryngeal cancer in the west pomerania region, cigarette smoking, size and primary site of the tumor, nodular metastases and clinical stage of the dis ...	2007	18260227
[malignant tumors of the nose and paranasal sinuses in the years 1971-2005 in the material of the otolaryngology clinic wim].	the aim of this study was retrospective analysis of evidence concerning to malignant tumors of the nasal cavity and the paranasal sinuses diagnosed in otolaryngology clinic of the military institute of the health service 1971-2005. the methods of therapy were also discussed.	2007	18260254
chordoma of a thoracic vertebra. a case report.	a 51-year-old woman presented with aspecific clinical symptoms of the thoracic spine. radiological survey showed a tumour mass at t3-t4. initial microscopic evaluation was suggestive of renal cell carcinoma metastasis. lack of a primary tumour and revision of the specimens changed the diagnosis into chordoma.	2007	18260501
serum n-terminal-pro-b-type natriuretic peptide (nt-pro-bnp) levels in hyperthyroidism and hypothyroidism.	e natriuretic peptides represent a novel diagnostic tool in the assessment of heart failure. n-terminal-pro-b-type natriuretic peptide (nt-probnp), a member of the natriuretic peptid family, is produced and released from cardiac ventricles. changes in cardiac functions are observed in thyroid dysfunctions. the aim of this study was to assess the changes in serum nt-probnp levels and to evaluate impact of thyroid hormones on serum nt-probnp in patients with hyperthyroidism and hypothyroidism. ser ...	2007	18271501
[thyroid hormone level change in patients undergoing oral and maxillofacial surgery].	to study the changes of thyroid hormone level in patients undergoing oral and maxillofacial surgery before and after operation, in order to provide some evidences for postoperative treatment and recovery.	2007	18278413
[comparison of translucency between enamel, dentin and vita veneer porcelain].	to compare the translucency between enamel, dentin and dental porcelain.	2007	18278420
[procaryotic expression, purification and identification of recombinant human prostate-specific antigen].	to produce recombinant human prostate-specific antigen (psa) by molecular cloning technology and to identify its activity.	2007	18284054
rna base damage and repair.	elaborate repair pathways counteract the deleterious effects of dna damage by mechanisms that are understood in reasonable detail. in contrast, repair of damaged rna has not been widely explored. this may be because aberrant rnas are generally assumed to be degraded rather than repaired. the reason for this view is well founded, since conserved surveillance mechanisms that degrade abnormal rnas are thoroughly documented. numerous proteins and protein-rna complexes are involved in the metabolism ...	2007	18289040
treatment results for 84 patients with base of tongue cancer.	for t2 tumors, surgery was indicated if functional preservation was possible. for t3/t4 tumors, the rate of primary disease control was not high and surgery frequently involved total laryngectomy. points that surgeons must heed when performing such surgery were delineated.	2007	18340583
carcinoid tumor of the larynx: clinical analysis of 33 cases in japan.	in regard to the treatment of carcinoid tumor of the larynx, irradiation is not effective and tumor excision with a minimum surgical margin is associated with a high risk of local recurrence. lymph node metastases to the neck are associated with worsening of the prognosis. to improve the survival rate, primary resection with a sufficient surgical margin (e.g. partial laryngectomy) and (elective) neck dissection is recommended, even for patients with early stage carcinoid tumors of the larynx.	2007	18340586
thyroid function in preterm infants 27-29 weeks of gestational age during the first four months of life: results from a prospective study comprising 80 preterm infants.	assessment of thyroid function in preterm neonates (ptn) 27-29 weeks of gestational age.	2007	18341087
high pressure liquid chromatographic analysis of in vivo metabolites of n-(substituted phenyl)-n'-(1,3,5-trimethyl pyrazole-4-yl)thioureas in rats.	the aim of this study was to investigate the in vivo metabolism of n-(substituted phenyl)-n'-(1,3,5-trimethylpyrazole-4-yl)thioureas (substrate) as model compounds in rats via hplc. the substrates, n-(4-fluoro/chlorophenyl)-n'-(1,3,5-trimethylpyrazole-4-yl)thioureas (t2 and t3), and their possible metabolites were synthesized and the structures of the compounds were elucidated both by spectral and elemental analysis. substrates were dissolved in 5% gum arabic and administered 100 mg/kg intraperi ...	2007	18348472
[outcome of surgical and adjuvant radiotherapy treatment of t3-t4 squamous cell carcinoma of the floor of the mouth: evaluation of oncological control and treatment related morbidity].	the aims of this study were to evaluate the therapeutic outcome and morbidity associated with management of squamous cell carcinoma (scc) t3-t4 of the floor of the mouth.	2007	18323327
[thoracoscopic sympathectomy for arterial ischemia of the upper extremities: a case report].	thoracoscopic surgery reduce the morbidity of sympathectomy. major indications of video-assisted sympathectomy (vat) include hyperhidrosis, raynaud's disease, causalgia, and reflex sympathetic dystrophy. because little information is available in the national and international literature vat sympathectomy in the treatment of upper extremities ischemia, we decided to present our first case. clinic case: the 38 years old patient was hospitalized for left upper-extremity ischemia (raynaud's syndrom ...	2007	18320797
a review of dna repair and possible dna-repair adjuvants and selected natural anti-oxidants.	few other organs have the environmental exposure-neoplasia relationship that has been observed between epithelial cutaneous malignancy and uvb exposure. a significant dna type of defective linking of dna nucleotides involves pyrimidine dimers. important insight into the molecular processes that affect the response of cells to uvb have been provided by the study of rare inherited diseases characterized by dna repair defects. nucleotide excision repair is the best characterized of these and its im ...	2007	18328204
[relevance of endoglin (cd105) vegf and p53 with invasion metastasis and prognosis of laryngeal carcinoma].	to evaluate the clinical significance of microvessel density (mvd) and investigate the relationship of endoglin (cd105), vegf and p53 protein and their significance of clinical pathology.	2007	18330257
[identification and phylogenetic analysis of one strain of lactobacillus delbrueckii subsp. bulgaricus separated from yoghourt].	for being further applied and studied, one strain of lactobacillus delbrueckii subsp. bulgaricus (wch9901) separated from yoghourt which had been identified by phenotype characteristic analysis was identified by 16s rdna and phylogenetic analyzed.	2007	18303633
psychoneuroendocrine effects of combined thyroxine and triiodothyronine versus tyrosine during prolonged antarctic residence.	we previously reported that cognitive function improves with thyroxine and that there is a circannual pattern to mood and human tsh during antarctic residence. to extend these findings, we examined the effects of tyrosine and a combined levothyroxine/liothyronine supplement in euthyroid men and women who spent the austral summer (n = 43) and/or winter (n = 42) in antarctica.	2007	18274206
[pelvic exenteration for t4 rectal cancer: a series of 15 ressectable cases].	pelvic exenteration is the best therapeutic choice for treatment of t4 rectal cancer. although, this operation still presents considerable mortality and high morbidity.	2007	18317645
[blood biochemical parameters of tilted primates periodically subjected to gravitational stimuli].	head-down tilting of primates (hot) is a universal method of studying the hypokinetic syndrome effects on functionality of various body systems. clinical biochemical blood assay was performed in a 25-day hdt experiment (-5 degrees) with 11 macaca rhesus. one group of animals was kept tilted all the time through, whereas the other was periodically returned into the orthostatic position for 30 to 120 minutes 4-5 times a week. dry chemistry was employed in biochemical analysis of blood serum and en ...	2007	18350838
comparison of selected diagnostic parameters in african grey parrots (psittacus erithacus) with normal plumage and those exhibiting feather damaging behavior.	feather damaging behavior is a common problem in african grey parrots (psittacus erithacus). to determine if differences in clinical test results could be detected in parrots with feather damaging behavior (fdb), we studied 51 parrots, including 24 with fdb, with a variety of diagnostic tests. a predictable stress hemogram was found after administration of thyroid-stimulating hormone in both normal birds and birds with fdb. birds with fdb had significantly lower lymphocyte counts and higher hete ...	2007	18351004
evaluation of the effects of chemical versus biological control on botrytis cinerea agent of gray mould disease of strawberry.	this study investigates on effects of four fungicide and six isolate from trichoderma and gliocladium on botrytis cinerea agent grey mold of strawberry under library and greenhouse condition. the effect of four fungicides i.e. benomyl, dichlofluanid, captan and triadimenol on b. cinerea was studied in the laboratory condition by method mixed poison to culture medium. it was shown that the fungicide including benomyl, triadimenol, dichlofluanid and captan were able to inhibit mycelial growth of b ...	2007	18396812
effects of olprinone on neuromuscular blockade caused by vecuronium.	we studied the effect of olprinone on neuromuscular blockade caused by vecuronium. thirty women undergoing nitrous oxide-oxygen-isoflurane anesthesia were randomly divided into olprinone (n=15) or control group (n=15). in the olprinone group, the patients received an intravenous initial loading dose of olprinone at a rate of 2 microg/kg/minute for 5 minutes, followed by a continuous infusion of olprinone at 0.3 microg/kg/minute. in the control group, the patients received normal saline. thirty m ...	2007	18402286
effects of zero-balanced ultrafiltration on procalcitonin and respiratory function after cardiopulmonary bypass.	the abnormal conditions to which blood is subjected during cardiopulmonary bypass (cpb) trigger an activation of the inflammatory response and cause pulmonary dysfunction. it has been suggested that high-volume, zero-balanced ultrafiltration (zbuf) facilitates clearance of inflammatory mediators and improves post-operative pulmonary function. procalcitonin, a newly discovered inflammatory mediator, has been found to be increased after cpb and has been proven to be an appropriate parameter for pr ...	2007	18416220
[survival analysis of completely resected stage iiib non-small cell lung cancer.]	background: most stage iiib (t4/n3) non-small cell lung cancer (nsclc) can not be cured via operation, but how is the outcome for those with t4 or occasionally n3 which can be completely resected? this paper retrospectively analyses the effects of the tumor characteristics and postoperative treatments on the survival of 51 patients with stage iiib nsclc completely resected in this hospital from january 1, 1997 to april 30, 2001. methods: the effects of clinical pathophysiological characteristics ...	2007	21114931
biochemistry of eukaryotic homologous recombination.	the biochemistry of eukaryotic homologous recombination caught fire with the discovery that rad51 is the eukaryotic homolog of the bacterial reca and t4 uvsx proteins; and this field is still hot. the core reaction of homologous recombination, homology search and dna strand invasion, along with the proteins catalyzing it, are conserved throughout evolution in principle. however, the increased complexity of eukaryotic genomes and the diversity of eukaryotic cell biology pose additional challenges ...	2007	21552479
effect of electrical stimulation on quality of tenderstretched chevon sides.	thirty male black bengal goats 5-8 years of age, slaughtered at the kolkata slaughter house, india, by the traditional 'halal' method, were used to assess the effect of electrical stimulation on tenderstretched sides of chevon carcasses. five groups (t1, t2, t3, t4 and t5) were treated with variable voltages of 35, 110, 330, 550, 1100 with fixed 50hz and 10pulses/s for a duration of 3min. different quality parameters, such as, fibre diameter, sarcomere length, water holding capacity (whc), ph, m ...	2007	22063666
tertiary hypothyroidism in a dog.	: a nine-year-old male entire labrador was diagnosed with pituitary dependent hyperadrenocorticism. following seven months of successful mitotane therapy, the dog presented with marked weight gain, seborrhoea and alopecia. routine clinicopathological analyses revealed marked hypercholesterolaemia. serum total and free thyroxine (t4) concentrations were below their respective reference ranges. serum thyroid stimulating hormone (ctsh) concentration was within reference range. tsh and thyrotropin r ...	2007	21851691
the force-velocity relationship of paralyzed quadriceps muscles during functional electrical stimulation cycling.	objectives. to investigate the nature of the force-velocity relationship on muscle forces and power outputs during functional electrical stimulation (fes)-evoked cycling at different pedaling cadences. materials and methods. ten patients with t4-t9 spinal cord injuries (asia a) performed fes-evoked cycling at 50 rev/min using a motorized isokinetic ergometer for 20 min, after which quadriceps crank torque and power were measured at 10, 30, and 50 rev/min. results. pedal cadence affected both ...	2007	22151814
a phase ii multicentre study of irinotecan (cpt 11) in combination with cisplatin (cddp) in metastatic or locally advanced penile carcinoma (eortc protocol 30992).	the aim of this study is to determine efficacy and feasibility of the combination regimen irinotecan and cisplatin in patients with cisplatin advanced penile cancer.	2008	18417462
tumor volume as a prognostic factor in oropharyngeal squamous cell carcinoma treated with primary radiotherapy.	tumor volume has been demonstrated to play a prognostic role in many head and neck cancers. the purpose of this study was to conduct an institutional review analyzing the correlation between tumor volume and locoregional control of oropharyngeal squamous cell cancer treated with primary radiotherapy.	2008	18418275
prognostic impact of primary tumor volume in patients with nasopharyngeal carcinoma treated by definitive radiation therapy.	tumor burden has been confirmed as one of the important indicators in disease control after treatment for various types of malignancies. this report aims to document the value of the primary tumor volume of nasopharyngeal carcinoma [gross tumor volume of the primary site (gtv-p)] in predicting the treatment outcome after high-dose definitive radiation therapy.	2008	18418278
oxidative stress regulates type 3 deiodinase and type 2 deiodinase in cultured rat astrocytes.	type 2 deiodinase (d2) and type 3 deiodinase (d3) locally achieve the determination of the concentration of t3, which binds to the thyroid hormone receptor with high affinity. d2 converts t4 into t3, and d3 degrades t4 and t3. neurons take up t3 released by astrocytes, the main cerebral site for the d2 expression. because oxidative stress is believed to be involved in several neurological disorders, we explored the effects of oxidative stress on d3 and d2 in primary culture of rat astrocytes. h2 ...	2008	18420745
cardiac output measurement in patients undergoing liver transplantation: pulmonary artery catheter versus uncalibrated arterial pressure waveform analysis.	cardiac output (co) and invasive hemodynamic measurements are useful during liver transplantation. the pulmonary artery catheter (pac) is commonly used for these patients, despite the potential complications. recently, a less invasive device (vigileo/flotrac) became available, which estimates co using arterial pressure waveform analysis without external calibration. in this study, we compared co obtained with a pac using automatic thermodilution, instantaneous co stat-mode (ico(sm)), and co obta ...	2008	18420863