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diseases associated with bovine viral diarrhea virus subtypes 1a and 2b in beef and dairy cattle in uruguay.bovine viral diarrhea virus (bvdv, pestivirus) causes significant economic losses to the livestock industry worldwide. although serological surveys show that bvdv exposure is widespread in cattle in uruguay, bvdv-associated diseases are greatly underreported. the aim of this work is to describe the epidemiological, clinical, pathological, and virological findings from spontaneous outbreaks of bvdv-associated diseases in cattle in uruguay. diagnostic investigations were performed during 6 spontan ...202031650465
the effect of bovine viral diarrhea virus introduction on milk production of dutch dairy herds.dairy cows are negatively affected by the introduction of bovine viral diarrhea virus (bvdv), and consequently, produce less milk. existing literature on potential milk production losses is based on relatively outdated data and hardly evaluates milk production loss in relation to a new bvdv infection in a surveillance system. this study determined the annual and quarterly loss in milk production of bvdv introduction in 3,126 dairy herds participating in the dutch bvdv-free program between 2007 a ...202033309379
a serological investigation of bovine enterovirus-1, bovine herpesvirus-1, bovine viral diarrhea virus, and parainfluenza-3 infections in camelsin western turkey.camels (camelus dromedarius) are bred in western turkey, particularly in the province of aydin, for touristic, social and cultural purposes. bovine enterovirus‑1 (bev‑1), bovine herpesvirus type‑1 (bhv‑1), bovine viral diarrhea virus (bvdv), and parainfluenza‑3 (pi‑3) virus infections are significant causes of health and/or economic concerns in several animal species. these agents have not been investigated in the camel population in turkey. the objective of this study was to serologically inves ...202033635614
guinea pig cytomegalovirus protective t cell antigen gp83 is a functional pp65 homolog for innate immune evasion and pentamer dependent virus tropism.the guinea pig is the only small animal model for congenital cmv but requires species-specific guinea pig cytomegalovirus (gpcmv). tegument protein gp83 is the presumed homolog of hcmv pp65 but gene duplication in the ul82-ul84 homolog locus in various animal cmv made it unclear if gp83 was a functional homolog. a gp83 null deletion mutant gpcmv (gp83dpc+) generated in the backdrop of glycoprotein pentamer complex (pc) positive virus, required for non-fibroblast infection, had normal growth kine ...202133658350
serological evidence of bovine viral diarrhea virus and peste des petits ruminants virus infection in alpacas (vicugna pacos) in shanxi province, northern china.bovine viral diarrhea virus (bvdv) and peste des petits ruminants virus (pprv) are two important pathogens associated with a variety of disease syndromes that result in substantial financial losses in animal husbandry. this study was performed to assess the seroprevalence of antibodies to bvdv and pprv among alpacas raised in shanxi province of northern china. serum samples were obtained from 246 alpacas in taiyuan (n=182), xinzhou (n=31), and jinzhong cities (n=33) of shanxi province, and serol ...202133939008
viral infections shared between water buffaloes and small ruminants in switzerland.importation of exotic animals that may harbor infectious agents poses risks for native species with potentially severe impacts on animal health and animal production. although the asian water buffalo (bubalus bubalis) population in europe is steadily increasing, its susceptibility to viral infections and its role for interspecies transmission is largely unknown. to identify viral infections that are shared between exotic water buffaloes and native small ruminants, we collected blood samples from ...202134166139
screening of eurasian tundra reindeer for viral sequences by next-generation sequencing.reindeer husbandry is essential for the livelihood and culture of indigenous people in the arctic. parts of the herding areas are also used as pastures for farm animals, facilitating potential transmission of viruses between species. following the covid-19 pandemic, viruses circulating in the wild are receiving increased attention, since they might pose a potential threat to human health. climate change will influence the prevalence of infectious diseases of both humans and animals. the aim of t ...202134207171
detection of pestivirus a (bovine viral diarrhea virus 1) in free-living wild boars in brazil.bovine viral diarrhea virus (bvdv) is a major pathogen in cattle herds. considering the epidemiological importance of pestiviruses and the process of wild boar invasion in brazil, this study aimed to investigate the presence of bvdv in free-living boars. forty-nine free-living wild boars were collected by exotic wildlife controller agents in 2017 and 2018. the presence of bvdv antibodies was evaluated in 42 serum samples using the virus neutralization test, and the detection of bvdv rna was perf ...202133638128
neurotropic bovine astrovirus-associated encephalitis: an underdiagnosed disease in south america?we describe a case of neurotropic bovine astrovirus-associated encephalitis in a jersey dairy cow from the department of san josé, uruguay. this represents the second case of this condition reported in the southern hemisphere. the cow was the only one affected in a herd of 70 cows, showing neurological signs with a 2-day clinical course, before dying spontaneously. histopathological examination revealed lymphocytic, histiocytic, and plasmacytic meningoencephalitis with neuronal necrosis, without ...202134148730
bohv-1-vectored bvdv-2 subunit vaccine induces bvdv cross-reactive cellular immune responses and protects against bvdv-2 challenge.the bovine respiratory disease complex (brdc) remains a major problem for both beef and dairy cattle industries worldwide. brdc frequently involves an initial viral respiratory infection resulting in immunosuppression, which creates a favorable condition for fatal secondary bacterial infection. current polyvalent modified live vaccines against bovine herpesvirus type 1(bohv-1) and bovine viral diarrhea virus (bvdv) have limitations concerning their safety and efficacy. to address these shortcomi ...202133451136
effects of multivalent brd vaccine treatment and temperament on performance and feeding behavior responses to a bvdv1b challenge in beef steers.this study examined the effects of multivalent respiratory vaccine treatment (vt) and animal temperament classification on feeding behavior traits, feed intake and animal performance in response to a bovine viral diarrhea virus (bvdv) challenge. nellore-angus crossbred steers (n = 360; initial body weight (bw) 330 ± 48 kg) were assigned to one of three vaccine treatments: non-vaccinated (non), modified live (mlv) and killed (kv) regarding respiratory viral pathogens, and inoculated intranasally ...202134359261
the participation of a malignant catarrhal fever virus and mycoplasma bovis in the development of single and mixed infections in beef and dairy cattle with bovine respiratory disease.the bovine respiratory disease (brd) complex is a multietiological and multifactorial disease associated with a wide range of viral and bacterial pathogens. this study evaluated the contribution of specific infectious disease agents in the development of brd in cattle from brazil and determined if a virus within the malignant catarrhal fever virus (mcfv) group and mycoplasma bovis, acting individually or in conjunction, can be associated with the development of brd. formalin-fixed paraffin-embed ...202134368279
seroprevalence of bovine viral diarrhea virus in local borana cattle breed and camels (camelus dromedarius) in ethiopia.bovine viral diarrhea, caused by bovine viral diarrhea virus (bvdv), has been considered a disease of cattle but is now emerging in camels. in ethiopia it has been detected in exotic and cross-bred dairy cattle but no information is available on its occurrence in indigenous cattle breeds and camels. this study was, therefore, conducted to estimate the prevalence of bvdv infection in indigenous borana cattle and camels (camelus dromedarius) in moyale and miesso pastoral districts.202134136370
bovine viral diarrhea virus subgenotype 1a in a mummified fetus from a brazilian dairy cattle herd.we describe the molecular analysis of a wild-type field strain of bovine viral diarrhea virus (bvdv) identified in a mummified fetus from a small brazilian dairy cattle herd. nucleic acids extracted from samples of the lung, liver, heart, spleen, and kidney were tested by pcr assays for bovine alphaherpesvirus 1, neospora caninum, leptospira spp., histophilus somni, and brucella abortus, a nested pcr assay for mycoplasma bovigenitalium and ureaplasma diversum, and a rt-pcr assay for bvdv. amplic ...202134078202
prevalence of bovine viral diarrhea virus antibodies and risk factors in dairy cattle in gondar city, northwest ethiopia.bovine viral diarrhea (bvd) is a disease that affects cattle and other ruminants worldwide and causes considerable economic losses. a cross-sectional study was carried out between december 2017 and july 2018 with the aim to estimate the prevalence of bovine viral diarrhea virus (bvdv) antibodies and to identify potential risk factors associated with the occurrence of the disease in dairy cattle in peri-urban areas of gondar city, northwest ethiopia. a total of 339 serum samples obtained from ran ...202133933916
molecular detection and genotyping of bovine viral diarrhea virus in western china.bovine viral diarrhea virus (bvdv) is an important global viral pathogen of cattle and other ruminants. to survey the infection rate and genetic diversity of bvdv in western china, a total of 1234 serum samples from 17 herds of dairy cattle, beef cattle and yak in 4 provinces were collected in 2019.202133531007
quantitative risk assessment of introduction of bvdv and bohv-1 through indirect contacts based on implemented biosecurity measures in dairy farms of spain.a stochastic quantitative risk assessment model was developed to estimate the annual probability of introduction of bovine viral diarrhea virus (bvdv) and bovine herpesvirus 1 (bohv-1) on 127 dairy farms through indirect contacts. vehicles transporting calves, cattle to slaughterhouse, dead animals, and mixture of feed, as well as visits by veterinarians and hoof trimmers, farm workers and contacts with neighbors were considered in the model. data from biosecurity questionnaires of each farm, sc ...202133453562
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