Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| alteration of plasma concentrations of opg before and after levothyroxine replacement therapy in hypothyroid patients. | osteoprotegerin (opg) is a newly identified inhibitor of bone resorption. recent studies indicate that opg also acts as an important regulatory molecule in the vasculature. hypothyroidism is associated with increased morbidity from cardiovascular disease. more recently, one study showed that plasma opg increases significantly, and decreases markedly with levothyroxine (l-t4) replacement therapy in patients with overt hypothyroidism (oht). the purpose of this study was to investigate the alterati ... | 2005 | 16483173 |
| intense 18-fluorodeoxyglucose uptake by the thymus on pet scan does not necessarily herald recurrence of thyroid carcinoma. | this is the first report of intense fluorodeoxyglucose positron emission tomography (fdg-pet) uptake secondary to thymic hyperplasia during follow-up for thyroid carcinoma. a 36-yr-old woman underwent thyroidectomy for a papillary carcinoma measuring 4 cm in diameter. after two doses of radioiodine, thyroglobulin (tg) remained detectable following recombinant human tsh (rhtsh) stimulation. a whole body scan (wbs) was negative. on computed tomography (ct) scan, a slightly lobulated thymus was vis ... | 2005 | 16483183 |
| left ventricular dysfunction in patients with subclinical hypothyroidism and its reversibility after hormone therapy. | to ascertain the presence of lv dysfunction in patients of subclinical hypothyroidism and its reversibility after hormone therapy. methods and meterial: thirty two patients with subclinical hypothyroidism (sh) were included in the study, along with thirty two age and sex matched individuals serving as controls. the patients with sh had normal serum t3 and t4 with an elevated tsh value. all patients and the controls were subjected to detailed echocardiographic examination for assessment of lv sys ... | 2005 | 16515232 |
| absolute and relative entropies from computer simulation with applications to ligand binding. | a comparison between two related methods, schlitter's formula and quasiharmonic analysis, for calculating absolute entropies from the covariance matrix of atomic fluctuations using molecular dynamics (md) simulations is presented. calculations for a set of organic compounds in the gas phase are compared to the corresponding statistical thermodynamics results for translational and rotational entropies and to experimental data for vibrational entropies. encouraging agreement is obtained for transl ... | 2005 | 16851719 |
| pka calculations in solution and proteins with qm/mm free energy perturbation simulations: a quantitative test of qm/mm protocols. | the accuracy of biological simulations depends, in large part, on the treatment of electrostatics. due to the availability of accurate experimental values, calculation of pka provides stringent evaluation of computational methods. the generalized solvent boundary potential (gsbp) and ewald summation electrostatic treatments were recently implemented for combined quantum mechanical and molecular mechanics (qm/mm) simulations by our group. these approaches were tested by calculating pka shifts due ... | 2005 | 16853267 |
| periodic dft calculations of the stability of al/si substitutions and extraframework zn2+ cations in mordenite and reaction pathway for the dissociation of h2 and ch4. | the local stability of al atoms replacing si in the zeolite framework is compared for all inequivalent tetrahedral (t) sites in mordenite. for al/si substitutions in two t sites the stable location of the compensating extraframework zn(2+) cation forming a lewis acid site is determined. in the most stable zn-mor structures zn(2+) is located in a small ring (5mr, 6mr) containing two al/si substitutions. in less stable structures the al atoms are placed at larger distances from each other and zn(2 ... | 2005 | 16853635 |
| [pituitary resistance to thyroid hormone--a case report]. | pituitary resistance to thyroid hormone is a very rare cause of hyperthyroidism. it is characterized by normal, or elevated tsh concentration with high concentration of t3 and t4. here, we present a case of a 24-year-old woman who suffered from mild thyrotoxicosis and diffuse goiter for several years. she had elevated ft3 and ft4 with slightly elevated tsh concentration. pituitary adenoma was excluded as magnetic resonance imaging showed normal pituitary gland, alpha subunit was within normal ra ... | 2005 | 16817146 |
| retrospective analysis of the treatment results for patients with squamous cell carcinoma of tonsil. | there has been no definitive randomized study to identify the optimal therapeutic regimen for treating squamous cell carcinoma of tonsil. the purpose of this study was to retrospectively evaluate the treatment outcome according to various combinations of surgery, radiation therapy and chemotherapy. | 2005 | 19956486 |
| [comparison of recovery time of bolus and continuous infusion mivacurium.]. | mivacurium is a short-acting neuromuscular blocker (nmb), with total duration not exceeding 24 minutes. early publications have reported no significant differences in recovery time, regardless of the route administration. however, clinical experience points out to longer recovery times when the drug is administered in continuous infusion. this study aimed at comparing recovery time of bolus administration and continuous infusion of mivacurium in a group of young adult patients. | 2005 | 19471808 |
| coherence characteristics of gamma-band eeg during rest and cognitive task in mci and ad. | the aim of this study is to investigate whether eeg coherence during different functional states facilitates the detection of ad-related eeg changes; and which brain regions these changes were. the eegs in both rest and performing the cognitive task states of 3 groups was recorded for coherence measure. the 3 groups are the mild cognitive impairment (mci) group, alzheimer's disease(ad) and the healthy control group. in rest state, coherence value of eeg for ad group was lower than that in other ... | 2005 | 17282809 |
| gene manipulation of fluorescent protein through site-selective hydrolysis by ce(iv)/edta. | previously we reported that gap-site, formed in substrate dna by using two oligonucleotide additives, was selectively hydrolyzed by ce(iv)/edta. herein this site-selective scission was used for gene manipulation, and green fluorescent protein (gfp) was converted to blue fluorescent protein (bfp). the sense strand of gfp was cleaved at predetermined site by using this system, and its upstream fragment was connected with the downstream of bfp gene by t4 dna ligase. in this manipulation, three amin ... | 2005 | 17150743 |
| host glucose metabolism mediates t4 and il-7 action on schistosoma mansoni development. | interleukin (il-)7 and thyroxin (t4) favor schistosoma mansoni development. their effect is similar, rather than identical; moreover, cotreatment acts synergistically on parasites. this questioned a common mediator to their action, which we hypothesized was host glucose metabolism. infection with s. mansoni resulted in an early peak in glycemia immediately followed by a peak of insulinemia (d7-21). in il-7 + t4 cotreated infected animals, the peak of insulin was abrogated. we further assessed th ... | 2005 | 17089737 |
| [clinical manifestations and endoscopic characteristics of kaposi's sarcoma in patients with acquired immunodeficiency syndrome]. | kaposi sarcoma may be the initial manifestation of immunodeficiency acquired syndrome (aids )in 30% of patients. the digestive tract is the thirth most affected site after the skin and lymph nodes. | 2005 | 17058981 |
| breast cancer in males: a pgimer experience. | male breast cancer is a rare disease representing 1% of all breast cancers and less than 1% of all cancers in men. because of its rarity, carcinoma breast has not been studied extensively and this prompted us to carry out this retrospective study. the aim of the study was to observe the clinical and pathological features, evaluate the prognostic factors and to co-relate the outcome in patients of male breast cancer. | 2005 | 17998622 |
| effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women. | abstract : purpose : this study investigated the effects of coleus forskohlii (cf) on body composition, and determined the safety and efficacy of supplementation. methods : in a double blind and randomized manner, 23 females supplemented their diet with forsleantrade mark (250 mg of 10% cf extract, (n = 7) or a placebo [p] (n = 12) two times per day for 12-wks. body composition (dexa), body weight, and psychometric instruments were obtained at 0, 4, 8 & 12 weeks of supplementation. fasting blood ... | 2005 | 18500958 |
| cloning of small rna molecules. | small rnas that are derived from dsrna precursors act as guide rnas during sequence-specific epigenetic regulation of eukaryotic gene expression. these small regulatory rnas are between 20 and 30 nucleotides in length, and fall into one or more of the following categories: small interfering rnas (sirnas), micrornas (mirnas), and heterochromatic sirnas (hsirnas). procedures to record the profile of small rnas expressed in cultured cells or tissues are described. the small rnas are directionally c ... | 2005 | 18265364 |
| [comparison between clinical and surgical-pathological tnm staging in patients with lung cancer.] | background: the accuracy of clinical tnm staging correlates with appropriate treatment in patients with lung cancer. the aim of this study is to evaluate the agreement between clinical and surgical-pathological staging in patients with lung cancer and analyze its cause in detail. methods: one hundred and fifty patients with lung cancer treated surgically from 2000 were enrolled randomly. clinical and surgical-pathological staging of them were made respectively according to the international syst ... | 2005 | 21187022 |
| speed and efficiency in walking and wheeling with novel stimulation and bracing systems after spinal cord injury: a case study. | to compare various novel and conventional systems for locomotion, a 25-year-old man was studied with motor complete spinal cord injury at the t4/5 level. he used various devices in the community, and changes in speed, physiological cost index (pci), and oxygen consumption were measured periodically. speed was fastest with a conventional manual wheelchair (nearly 120 m/min in a 4-min test). speed was about 30% less, but the pci was lowest (highest efficiency) using functional electrical stimulati ... | 2005 | 22151555 |
| [a method using long primers for cloning the upstream sequence of delta-6 fatty acid desaturases gene of thamnidium elegans by nested inverse pcr]. | thamnidium elegans is a kind of phycomycete that produces essential unsaturated fatty acids, particularly y-linolenic acid. in this process, delta6-fatty acid desaturase (d6d) plays a key role due to its enzymatic properties that catalyze the delta6 site dehydrogenation of precursor linoleic acid (18:2delta(9, 12) n-6) and a-linolenic acid (18:3delta(9, 12, 15) n-3). this reaction is the first and rate-limiting step of highly unsaturated fatty acids (hufa) synthesis pathways. after we have isola ... | 2006 | 16894891 |
| computed tomographic morphometry of thoracic pedicles: safety margin of transpedicular screw fixation in malaysian malay population. | a cross-sectional study of thoracic pedicle morphometry (t1-t12) of 180 malaysian malay patients obtained from computed tomographic scan. | 2006 | 16845341 |
| the extremes of spinal motion: a kinematic study of a contortionist in an open-configuration magnetic resonance scanner: case report. | observational case study on a female contortionist. | 2006 | 16845345 |
| gastroesophageal junction adenocarcinoma: what are the factors influencing long-term survival? | the incidence of gastroesophageal junction adenocarcinoma is increasing. about 30% of the tumors cannot be completely resected, and 40% of the patients relapse after complete resection. there is much controversy over the role of neoadjuvant therapy, the approach route, lymphadenectomy, and the extent of esophageal resection. the aim of our study was to report our experience in the treatment of gastroesophageal junction adenocarcinoma. from january 1987 until february 2005, 157 patients (125 men, ... | 2006 | 16845860 |
| hypothyroidism in the pregnant woman. | around 1-2% of pregnant women receive levothyroxine treatment for overt hypothyroidism. this condition, which commonly has an autoimmune cause, is defined as a low plasma free thyroxine (t4) concentration and a raised plasma thyroid-stimulating hormone (tsh) concentration. around another 2.5% of pregnant women have subclinical ('compensated') hypothyroidism, which is defined as a raised plasma tsh concentration with a normal free t4 concentration. here we review the evidence on whether such prob ... | 2006 | 16846139 |
| [therapeutic modalities of nasopharyngeal adenoid cystic carcinoma]. | to grasp clinical characteristics, therapeutic methods and prognosis of the patients with nasopharyngeal adenoid cystic carcinoma, and explore the optimal therapeutic modalities. | 2006 | 16848289 |
| acting via a cell surface receptor, thyroid hormone is a growth factor for glioma cells. | recent evidence suggests that the thyroid hormone l-thyroxine (t4) stimulates growth of cancer cells via a plasma membrane receptor on integrin alphavbeta3. the contribution of this recently described receptor for thyroid hormone and receptor-based stimulation of cellular mitogen-activated protein kinase [mapk; extracellular signal-regulated kinase 1/2 (erk1/2)] activity, to enhancement of cell proliferation by thyroid hormone was quantitated functionally and by immunologic means in three glioma ... | 2006 | 16849576 |
| ernst ferdinand sauerbruch and his ambiguous role in the period of national socialism. | the role of german physicians under national socialism is highly controversial. we show that ferdinand sauerbruch, one of twentieth century's most outstanding surgeons and chair of surgery at berlin's charité from 1927 to 1949, openly supported national socialism in his public statements and in his position as head of the medical section of the reich research council. he was appointed state councilor and received the knight's cross of the war merit cross by the national socialists. but sauerbruc ... | 2006 | 16858197 |
| adjuvant therapy for ampullary carcinomas: the mayo clinic experience. | to determine the effects of adjuvant radiotherapy and chemotherapy for carcinoma of the ampulla of vater. | 2006 | 16863684 |
| 18f-fdg-pet for evaluation of the response to concurrent chemoradiation therapy with intensity-modulated radiation technique for stage t4 nasopharyngeal carcinoma. | this article evaluates [18f] fluorodeoxyglucose positron emission tomography (18f-fdg-pet) findings as a predictor for local responders (r) vs. nonresponders (nr) in nasopharyngeal carcinoma (npc) patients with stage t4 lesions, before and at 3 months after completion of concurrent chemotherapy and radiation therapy (ccrt). | 2006 | 16863922 |
| multivariate analyses of locoregional recurrences and skin complications after postmastectomy radiotherapy using electrons or photons. | we retrospectively analyzed factors of locoregional (lr) recurrence and skin complications in patients after postmastectomy radiotherapy (pmrt). | 2006 | 16863925 |
| laparoscopic resection for rectal cancer: a prospective analysis of thirty-month follow-up outcomes in 312 patients. | this study aimed to prospectively evaluate operative safety and mid-term oncologic outcomes of laparoscopic rectal cancer resection performed by a single surgeon. | 2006 | 16865622 |
| [transdermal carbimazole for the treatment of feline hyperthyroidism]. | orally administered antithyroid drugs are frequently used to treat hyperthyroidism in cats; however, the non-cooperative behaviour of some cats may make it difficult to administer tablets. the aim of this study was to develop a carbimazole ointment for application to the inner pinna of the ear and to test its effectiveness in 13 cats with hyperthyroidism. laboratory investigations were performed before, and 4, 8, and 12 weeks after start of the treatment. laboratory data for 9 cats were availabl ... | 2006 | 16866160 |
| adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase ii study. | the safety and efficacy of gemcitabine and concurrent radiation to the upper abdomen followed by weekly gemcitabine in patients with resected pancreatic cancer was determined. patients with resected adenocarcinoma of the pancreas were treated with intravenous gemcitabine administered twice-weekly (40 mg m(-2)) for 5 weeks concurrent with upper abdominal radiation (50.4 gy in 5(1/2) weeks). at the completion of the chemoradiation, patients without disease progression were given gemcitabine (1000 ... | 2006 | 16868545 |
| hypopituitarism following severe traumatic brain injury. | although hypopituitarism is a known complication of traumatic head injury, it may be under-recognized due to its subtle clinical manifestations. to address this issue, we determine the prevalence of neuroendocrine abnormalities in patients rehabilitating from severe traumatic brain injury (glasgow coma scale < or = 8). 76 patients (mean age 39 +/- 14 yr; range 18-65; 53 males and 23 females; bmi 25.8 +/- 4.2 kg/m2; mean +/- sd) with a severe traumatic brain injury, an average of 22 +/- 10 months ... | 2006 | 16868891 |
| [mechanical cervical esophagogastric anastomosis after esophagectomy for cancer]. | fibrous stenosis of the esophagogastric cervical anastomosis remains a significant complication occurring in up to one third of cases. trying to reduce the incidence of this complication, we describe our technique of cervical esophago-gastric anastomosis using endoscopic linear stapler which seems to reduce the incidence of fibrous stricture formation after resection of esophageal cancer. | 2006 | 16871138 |
| [adjuvant treatment of colorectal cancer]. | colorectal cancer is a real national healthy problem because of high frequency and high rate of mortality. folfox4 is the new standard treatment since publication of mosaic' results. irinotecan associated with 5 fluorouracil (5fu) and leucovorin (lv) failed to demonstrate superiority over lv modulated 5fu. oral fluoropyrimidines (capecitabine or uft + lv) are an effective alternative to intravenous 5fu and lv. in stage ii colon cancer, treatment strategies are more debated. some data suggest tha ... | 2006 | 16873077 |
| spinal anesthesia using a continuous spinal catheter for cesarean section in a parturient with prior surgical correction of scoliosis. | this case report demonstrates the successful anesthetic management of cesarean section for a 29-year-old primiparous parturient with a past history of a scoliosis operation at 13 years of age. an isola hook and screw-rod system had been implanted as posterior spinal instrumentation at the level of t3-l3. we titrated hyperbaric bupivacaine 7 mg combined with fentanyl 15 microg through a continuous spinal catheter, placed with a catheter-over-needle technique in order to avoid unintentional wide s ... | 2006 | 16897244 |
| a bioequivalence study of levothyroxine tablets versus an oral levothyroxine solution in healthy volunteers. | probably for genetic reasons a substantial part of the greek population requires levothyroxine treatment. since commercially available levothyroxine was first marketed, the manufacture and storage of the drug in tablet form has been complicated and difficult; and as cases of therapeutic failure have frequently been reported following treatment with this medicinal agent, quality control is an essential factor. due to the unreliability of levothyroxine-based commercial products, in the present stu ... | 2006 | 16898074 |
| characterization of the aldehyde reactive probe reaction with ap-sites in dna: influence of ap-lyase on adduct stability. | alkoxyamines react with the open-chain aldehyde form of ap-sites in dna to produce open-chain aldehyde oximes. here we characterize the effect of ap-site cleavage by yeast ap-endonuclease 1 (apn1) or t4 pyrimidine dimer dna glycosylase/ap-lyase (t4 pdg) on the efficiency and stability of the alkoxyamine aldehyde reactive probe (arp) condensation reaction with ap-sites. the results indicate that (1) reaction of arp with the open-chain aldehyde equilibrium form of the ap-site was less efficient th ... | 2006 | 16898421 |
| [clinical analysis of bladder cancer]. | we report our clinical experiences of treatment for bladder cancer. | 2006 | 16898593 |
| [cranial nerve palsies due to skull base metastases in patients with prostate cancer: a report of two cases]. | two patients with prostate cancer showed cranial nerve palsies due to skull base metastases. case 1: a 64-year-old man had prostate cancer (t4 n0 m1, gleason score 7, prostate-specific antigen [psa] level 372 ng/ml) with multiple bone metastases. seventy-seven months after initiation of therapy, he had an articulation disorder and palsy of the left side of the tongue, with 12th cranial nerve palsy. case 2: a 75-year-old man had a prostate cancer (t3b n0 m1, gleason score 7, psa level 177 ng/ml) ... | 2006 | 16898599 |
| radiotherapy of t4 squamous cell carcinoma of the skin of nasal pyramid. | 2006 | 16898916 | |
| effects of seasonal and physiological variations on the serum chemistry, vitamins and thyroid hormone concentrations in sheep. | the aim of this study was to investigate the possible effects of the reproductive status and seasonal variations on the serum chemistry and vitamin status and their relationships with the thyroid hormones in sakiz-awassi crossbreed sheep. the sheep (n = 34) were divided into two groups. the first group (n = 22) was mated; the second group (n = 12) was not mated. their serum samples were collected four times a year at the each season and under reproductive status. the periods are 1, early pregnan ... | 2006 | 16901267 |
| pulmonary resections for t4 non-small cell lung cancer with support of cardiopulmonary bypass. | 2006 | 16901710 | |
| [stomal recurrence after total laryngectomy]. | stomal recurrence after total laryngectomy is a very serious complication, in general with dismal prognosis. there are only a few possibilities of treatment, so stress should be put on prevention. | 2006 | 16903329 |
| potential role of thyroid hormones and prolactin in the programming of photorefractoriness in turkey hens. | the domestic turkey hen is a seasonal breeder, requiring a period of short days to establish photosensitivity and a long day length to initiate egg production. the reproductive season is then limited by the onset of photorefractoriness (pr), which causes a decline, and then termination, of egg laying. in passerine birds, pr is programmed early in the reproductive season by the presence of thyroid hormones and a long photoperiod. high circulating prolactin (prl) is thought to hasten the onset of ... | 2006 | 16903478 |
| the value of serum albumin in pretreatment assessment and monitoring of therapy in hiv/aids patients. | we sought to examine the utility of serum albumin measurement in staging aids and monitoring patients' response to therapy. | 2006 | 16903978 |
| adenoid cystic carcinoma of the head and neck treated by surgery with or without postoperative radiation therapy: prognostic features of recurrence. | this study sought to review a single-institution experience with the management of adenoid cystic carcinoma of the head and neck. | 2006 | 16904520 |
| survival benefit associated with adjuvant androgen deprivation therapy combined with radiotherapy for high- and low-risk patients with nonmetastatic prostate cancer. | the use of adjuvant androgen deprivation therapy (adt) combined with radiotherapy has become common in low-risk patients, although clinical trials have focused primarily on high-risk patients. this study examines the effectiveness of adjuvant adt combined with radiotherapy for a wide range of patients treated in the 1990s. | 2006 | 16904843 |
| a long-term evaluation of the mandibular schwarz appliance and the acrylic splint expander in early mixed dentition patients. | the aim of this prospective longitudinal clinical study was to evaluate the short-term and long-term changes in dental-arch dimensions in patients treated with either an acrylic splint rapid maxillary expander alone (rme-only) or a rapid maxillary expander combined with a mandibular removable schwarz plate (rme-sz) in the early mixed dentition, followed later by fixed appliances in the permanent dentition. | 2006 | 16905065 |
| staging refinements in renal cell carcinoma. | accurate pathologic staging systems provide valuable prognostic information. as our understanding of the biology of renal cell carcinoma improves, so does the staging system has undergo periodic modification. the modification of the tumor-node-metastasis staging system in 2002 has been applied to various populations, and several changes have been proposed. | 2006 | 16905974 |
| dynamical disentanglement across a point contact in a non-abelian quantum hall state. | we analyze the tunneling of non-abelian quasiparticles between the edges of a quantum hall droplet at the landau level filling fraction nu=5/2, assuming that the electrons in the first excited landau level organize themselves in the non-abelian moore-read pfaffian state. by bosonizing the edge theory, we show that an effective spin-1/2 degree of freedom emerges in the description of a point contact. we show how the crossover from the high-temperature regime of weak quasiparticle tunneling betwee ... | 2006 | 16907526 |
| impact of iron particles in groundwater on the uv inactivation of bacteriophages ms2 and t4. | to investigate the impact of iron particles in groundwater on the inactivation of two model viruses, bacteriophages ms2 and t4, by 254-nm ultraviolet (uv) light. | 2006 | 16907824 |
| prevalence of thyroid autoimmunity in sporadic idiopathic hypoparathyroidism in comparison to type 1 diabetes and premature ovarian failure. | thyroid autoimmunity is the most common coexistent endocrinopathy in type 1 diabetes (t1d), addison's disease, and premature ovarian failure (pof). although the role of autoimmunity is being investigated in patients with sporadic idiopathic hypoparathyroidism (sih), there is little information on coexistent thyroid autoimmunity. | 2006 | 16895958 |
| clofibrate increases hepatic triiodothyronine (t3)- and thyroxine (t4)-glucuronosyltransferase activities and lowers plasma t3 and t4 concentrations in pigs. | in rats, clofibrate acts as a microsomal enzyme inducer and disrupts the metabolism of thyroid hormones by increasing hepatic glucuronidation of thyroxine. whether similar effects occur in the pig has not yet been investigated. this study was performed to investigate the effect of clofibrate treatment on metabolism of thyroid hormones in pigs. to this end, an experiment with 18 pigs, which were assigned to two groups, was performed. one group received a control diet, and the other group was fed ... | 2006 | 16896063 |
| multimodal imaging of esophagus and cardia cancer before and after treatment. | prognosis and treatment of esophagus and cardia cancer (ecc) depend on the precision with which the disease is staged according to the american joint committee of cancer (ajcc) criteria. imaging modalities normally used in clinical staging are esophagography, esophagoscopy, endoscopic ultrasound (eus), computed tomography (ct) and positron emission tomography- ct fusion (ct-pet). the combination of these methods is crucial in determining not only the right diagnosis but also the stage and follow ... | 2006 | 16896560 |
| rhabdomyolysis associated with hyperthyroidism. | nontraumatic rhabdomyolysis has been associated with alcohol and drug abuse, seizures, strenuous exercise, muscle hypoperfusion, hyperthermia, electrolyte disturbances, diabetic coma, and hypothyroidism. hyperthyroidism can be associated with several neuromuscular manifestations, such as thyrotoxic myopathy and thyrotoxic periodic paralysis, both associated with weakness and normal creatine phosphokinase levels. there have been only three reported cases of rhabdomyolysis as a result of thyrotoxi ... | 2006 | 16909061 |
| primary treatment of the anterior vocal commissure squamous carcinoma. | squamous cell carcinoma may involve the anterior commissure (ac) area of the laryngeal glottis, and can be grouped morphologically into four groups; (1) tumor confined to the ac, (2) tumor involving one cord and the ac, (3) tumor involving the ac and a portion of both vocal cords, and (4) tumor involving a greater part of one cord and crossing over to involve a variable length of the other cord. some of these patients when evaluated by imaging, either ct and/or mri, may demonstrate thyroid carti ... | 2006 | 16909217 |
| piperine, an active principle from piper nigrum, modulates hormonal and apo lipoprotein profiles in hyperlipidemic rats. | to study the effect of piperine, an alkaloid, on thyroid hormones and apolipoproteins in high-fat-diet (hfd) and antithyroid drug-induced hyperlipidemic rats. | 2006 | 16910313 |
| sodium iodide i 131 treatment of dogs with nonresectable thyroid tumors: 39 cases (1990-2003). | to determine outcome for dogs with nonresectable thyroid carcinomas treated with sodium iodide i 131 and identify factors associated with outcome. | 2006 | 16910854 |
| correlation between serum osteoprotegerin and biomarkers of bone metabolism during anti-thyroid treatment in patients with graves' disease. | bone turnover is increased in favor of resorption in hyperthyroid patients. we aimed to examine whether osteoprotegerin (opg), which has an inhibitory effect on osteoclasts, is correlated with any biomarkers for bone turnover in graves' disease. twenty-one patients with graves' disease were examined in this study, before and after treatment. briefly, opg, calcium, phosphorus, pth, free t3, free t4, tsh, tsh receptor antibody and tsh-stimulating antibody were measured. elevated serum opg levels w ... | 2006 | 16912510 |
| immune function, pain, and psychological stress in patients undergoing spinal surgery. | this study was an exploratory repeated measures design comparing patients undergoing two magnitudes of surgery in the lumbar spine: lumbar herniated disc repair and posterior lumbar fusion. | 2006 | 16915080 |
| serum tsh levels in smokers and non-smokers. the 5th tromsø study. | cigarette smoking has a number of effects on the thyroid gland including the development of graves' disease and thyroid multinodularity. however, the effect of smoking on thyroid function is more uncertain. | 2006 | 16915535 |
| prevention strategy for post dural puncture headache. | we report the anesthetic management of a parturient after an unintentional dural puncture while performing epidural anaesthesia for caesarean section and the strategy to prevent postdural puncture headache (pdph). we injected the cerebrospinal fluid (csf) back into the subarachnoid space and then administered intrathecal 1.5 ml 0.5% hyperbaric bupivacaine and fentanyl 20 microg to maintain csf volume via epidural needle. the epidural catheter was inserted following re-identification of the epidu ... | 2006 | 16916188 |
| structure of t4 pyrimidine dimer glycosylase in a reduced imine covalent complex with abasic site-containing dna. | the base excision repair (ber) pathway for ultraviolet light (uv)-induced cyclobutane pyrimidine dimers is initiated by dna glycosylases that also possess abasic (ap) site lyase activity. the prototypical enzyme known to catalyze these reactions is the t4 pyrimidine dimer glycosylase (t4-pdg). the fundamental chemical reactions and the critical amino acids that lead to both glycosyl and phosphodiester bond scission are known. catalysis proceeds via a protonated imine covalent intermediate betwee ... | 2006 | 16916523 |
| electroencephalographic changes after one night of sleep deprivation. | total or partial sleep deprivation (sd) causes degrading effects on different cognitive and psychomotor functions that might be related to electrophysiological changes frequently observed. in the present study, we investigated the effects of one night of sleep deprivation on waking eeg. experimental protocol consisted of recording electroencephalographic data from eleven healthy young subjects before (baseline) and after (time 2) one night of sleep deprivation. a natural log transformation was c ... | 2006 | 16917606 |
| hypothyroidism as a protective factor in acute stroke patients. | it has been reported that hypothyroidism is associated with better survival in elderly persons. we investigated possible associations of thyroid status with clinical outcome in patients with acute stroke. | 2006 | 16918958 |
| distinct endocrine effects of chronic haloperidol or risperidone administration in male rats. | antipsychotic drugs have been used effectively for the treatment of schizophrenia symptoms, but they are often associated with metabolic side effects such as weight gain and endocrine disruptions. to investigate the possible mechanisms of antipsychotic-induced metabolic effects, we studied the impact of chronic administration of a typical antipsychotic drug (haloperidol) and an atypical antipsychotic (risperidone) to male rats on food intake, body weight, adiposity, and the circulating concentra ... | 2006 | 16919686 |
| [effects of mixed cypermethrin and methylparathion on endocrine hormone levels and immune functions in rats: i. dose-response relationship]. | to study dose-response relationship effects of mixed cypermethrin and methyl parathion on reproductive hormones, thyroid hormones, and immune functions in rats. | 2006 | 16921741 |
| [significance of expressions of bone morphogenetic protein 2 and 4 in prostatic carcinoma]. | to determine the expression of bone morphogenetic protein 2 and 4 (bmp-2 and bmp-4) in prostatic carcinoma (pca) and investigate their relationship with clinical stage and gleason score of tumor. | 2006 | 16519147 |
| is pre-operative radiotherapy necessary in t-t rectal cancer with tme? | the indications for pre-operative radiotherapy in rectal cancer are still unclear with the exception of t4 tumours. the aim of this study was to assess local and overall recurrence in patients with t1-t3 rectal cancers undergoing total mesorectal excision (tme). | 2006 | 16519635 |
| analysis of prognostic factors in patients with transitional cell carcinoma of the bladder treated with radical cystectomy. | to analyze the results of the treatment of transitional cell carcinoma (tcc) of the bladder with radical cystectomy and determine which prognostic factors can be utilized as disease-free survival and cancer-specific survival independent variables. | 2006 | 16519826 |
| feasibility and accuracy of trus in the pre-treatment staging for rectal carcinoma in general practice. | transrectal ultrasonography (trus) is the diagnostic tool of choice for local staging of rectal carcinoma. the accuracy in determining of tumour infiltration depth has been reported to reach 95% (on average, 85%). the aim of the study was to analyse the diagnostic accuracy of the trus in the clinical routine. | 2006 | 16520014 |
| structure, stability, and biological activity of bacteriophage t4 gene product 9 probed with mutagenesis and monoclonal antibodies. | gene product (gp) 9 connects the long tail fibers and triggers the structural transition of t4 phage baseplate at the beginning of infection process. gp9 is a parallel homotrimer with 288 amino acid residues per chain that forms three domains. to investigate the role of the gp9 amino terminus, we have engineered a set of mutants with deletions and random substitutions in this part. the structure of the mutants was probed using monoclonal antibodies that bind to either n-terminal, middle, or c-te ... | 2006 | 16520061 |
| [a universal high-throughput novel method of constructing the vectors]. | in this paper, a simple universal high-throughput method of constructing the vectors was developed. it could add proper adapter when the pcr primers were designed, and the purpose fragments were cloned by pcr, and the various complementary sticky ends were created by t4 dna polymerase's 3' -exodeoxyribonuclease activity. if all these fragments were put together with dna ligase, they would recombinate in an orientation. if they had been transformated, the tansformants would be identified. let's t ... | 2006 | 16520319 |
| [changes in serum leptin levels in patients with surgically induced stress responses]. | to explore the effect of operative trauma induced stress responses on serum leptin levels. | 2006 | 16524513 |
| structure and substrate recognition of the escherichia coli dna adenine methyltransferase. | the structure of the escherichia coli dam dna-(adenine-n6)-methyltransferase in complex with cognate dna was determined at 1.89 a resolution in the presence of s-adenosyl-l-homocysteine. dna recognition and the dynamics of base-flipping were studied by site-directed mutagenesis, dna methylation kinetics and fluorescence stopped-flow experiments. our data illustrate the mechanism of coupling of dna recognition and base-flipping. contacts to the non-target strand in the second (3') half of the gat ... | 2006 | 16524590 |
| adjuvant therapy in colon cancer--what, when and how? | bolus fluorouracil and leucovorin has been accepted as the standard adjuvant therapy in stage iii colon cancer for many years. new drugs such as irinotecan, oxaliplatin and oral fluoropyrimidines have all completed phase iii randomised evaluation in colon cancer. several of these studies have been reported in the last 24 months. oxaliplatin-based chemotherapy is now emerging as the new standard of care in adjuvant treatment of stage iii colon cancer. the advent of monoclonal antibodies such as c ... | 2006 | 16524974 |
| anti-thyroid peroxidase antibody and vitiligo: a controlled study. | vitiligo is an acquired depigmenting disorder due to destruction of melanocytes. although many theories have been suggested for its pathogenesis, the role of autoimmunity is the most popular one. the association of vitiligo with autoimmune thyroid diseases and the increased prevalence of autoantibodies including thyroid autoantibodies in vitiligo favor this role. our objective was to compare the frequency of thyroid peroxidase antibody (anti-tpo) in vitiligo patients with healthy subjects in ira ... | 2006 | 16526964 |
| small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses. | small cell neuroendocrine carcinoma (snec) of the sinonasal tract is a rare disease. | 2006 | 16526967 |
| involvement of level i neck lymph nodes and submandibular gland in laryngeal and/or hypopharyngeal squamous cell carcinoma. | to investigate the prevalence of level i neck lymph node metastases or submandibular nodal metastases in laryngeal and/or hypopharyngeal squamous cell carcinoma (scc). | 2006 | 16527029 |
| [a retrospective study of malignant parotid tumors]. | the clinical features of 74 patients (39 men, 35 women; mean age, 62 years) with malignant parotid tumors were retrospectively investigated. according to the tnm classification, 4 patients were classified as t1, 9 as t2, 6 as t3, and 55 as t4. fifty cases were staged as n0, 9 as n1, 14 as n2 and 1 as n3. tumors located in both lobes of the parotid gland were the most frequent type of tumor (49%). twenty-four percent of the 74 patients exhibited facial nerve palsy before treatment. facial palsy w ... | 2006 | 16529017 |
| tumor size improves the accuracy of tnm predictions in patients with renal cancer. | current staging for renal cancer (rc) does not directly rely on tumor size. we examined the increment in accuracy related to inclusion of pathologically determined tumor size in prediction of nodal metastases (n+), distant metastases (m+), and cancer-specific survival (css). | 2006 | 16530322 |
| cryo-em structure of a bacteriophage t4 gp24 bypass mutant: the evolution of pentameric vertex proteins in icosahedral viruses. | many large viral capsids require special pentameric proteins at their fivefold vertices. nevertheless, deletion of the special vertex protein gene product 24 (gp24) in bacteriophage t4 can be compensated by mutations in the homologous major capsid protein gp23. the structure of such a mutant virus, determined by cryo-electron microscopy to 26 angstroms, shows that the gp24 pentamers are replaced by mutant major capsid protein (gp23) pentamers at the vertices, thus re-creating a viral capsid prio ... | 2006 | 16530424 |
| mechanism of a hereditary cataract phenotype. mutations in alphaa-crystallin activate substrate binding. | we present a novel hypothesis for the molecular mechanism of autosomal dominant cataract linked to two mutations in the alphaa-crystallin gene of the ocular lens. alphaa-crystallin is a molecular chaperone that plays a critical role in the suppression of protein aggregation and hence in the long term maintenance of lens optical properties. using a steady state binding assay in which the chaperone-substrate complex is directly detected, we demonstrate that the mutations result in a substantial in ... | 2006 | 16531622 |
| chronic administration of anabolic androgenic steroid alters murine thyroid function. | the administration of anabolic-androgenic steroids (aas) to improve athletic performance has increased notably during the past three decades, even among nonathletes. thyroid function is affected by aas use in humans, although the mechanisms of the effects of aas are unclear. we evaluated the effects on thyroid function of supraphysiologic doses of nandrolone decanoate (deca), which is one of the most anabolic-androgenic steroids (aas) used. | 2006 | 16531893 |
| effects of an entire season on physical fitness changes in elite male handball players. | fifteen elite male handball players were studied to examine the effects of an entire season of play on physical fitness and throwing velocity. | 2006 | 16531907 |
| euthyroid sick syndrome in trauma patients with severe inflammatory response syndrome. | to investigate the alternations of thyroid hormone in traumatic patients with severe inflammatory response syndrome (sirs). | 2006 | 16533439 |
| [staging 915 cases of nasopharyngeal carcinoma after simple radical radiotherapy (part ii)--checkout of ajcc/uicc staging system (1997)]. | on the basis of our previous research, this study was to validate the rationality of ajcc/uicc staging system (1997) of nasopharyngeal carcinoma (npc), and to provide some suggestions. | 2006 | 16536975 |
| [three-dimensional conformal radiotherapy for primary nasopharyngeal carcinoma and analysis of locoregional recurrence]. | the efficacy of routine two-dimensional radiotherapy for primary nasopharyngeal carcinoma (npc) is dissatisfied, while three-dimensional conformal radiotherapy (3-d crt) can optimize irradiation dose distribution. this study was to explore the efficacy of 3-d crt on npc, and investigate dosimetric factors of locoregional failure. | 2006 | 16536988 |
| [neck relapse-related factors of cn0 stage supraglottic cancer]. | the occult lymph node metastasis rate of supraglottic cancer is high, and the treatment of occult lymph node metastasis is important. this study was to explore the related factors, treatment, and prognosis of occult lymph node metastasis of supraglottic cancer. | 2006 | 16536994 |
| microvessel density in head and neck squamous cell carcinoma primary tumors and its correlation with clinical staging parameters. | our objective was to assess angiogenesis in head and neck squamous cell primary tumors and measure its correlation with tumor site and clinical and pathologic staging parameters. | 2006 | 16540897 |
| effects of ulinastatin treatment on the cardiopulmonary bypass-induced hemodynamic instability and pulmonary dysfunction. | to examine the association between decreased release of proinflammatory cytokines in response to urinary trypsin inhibitor pretreatment and decreased myocardial and lung injury after cardiopulmonary bypass. | 2006 | 16540949 |
| age-related differences in hormonal and nutritional impact on lean anorexia nervosa bone turnover uncoupling. | in anorexia nervosa (an) patients osteoporosis occurs within a framework of multiple hormonal abnormalities as a result of bone turnover uncoupling, with decreased bone formation and increased bone resorption. the aim of study was to evaluate the hormonal and nutritional relationships with both of these bone remodeling compartments and their eventual modifications with age. | 2006 | 16541206 |
| probing the genetic basis for thyrotropin receptor antibodies and hyperthyroidism in immunized cxb recombinant inbred mice. | immunization with adenovirus encoding the tsh receptor (tshr) or its a-subunit induces graves' hyperthyroidism in balb/c and balb/c x c57bl/6 offspring but not c57bl/6 mice. high-resolution genetic maps are available for 13 recombinant inbred cxb strains generated from balb/c x c57bl/6 progeny by repeated brother x sister matings to establish fully inbred lines. cxb strains were studied before and after a-subunit adenovirus immunization for tshr antibodies (tbi, inhibition of tsh binding), serum ... | 2006 | 16543368 |
| effects of growth-promoting agents and season on blood metabolites and body temperature in heifers. | to assess the efficacy of growth-promoting agents among seasons, triiodothyronine (t3), thyroxine (t4), plasma urea nitrogen (pun), igf-i, and tympanic temperature (tt) were measured in summer and winter studies. heifers (n = 9/pen) were allotted to 12 pens in both december and june. pens were assigned to 1 of 6 growth promotant treatments: control (no growth promotant), estrogenic implant (e), trenbolone acetate implant (tba), e + tba (et), melengestrol acetate (mga), and et + mga (etm). blood ... | 2006 | 16543582 |
| adenocarcinomas of esophagogastric junction: multi-detector row ct to evaluate early response to neoadjuvant chemotherapy. | to prospectively evaluate multi-detector row computed tomography (ct) in the assessment of early response during neoadjuvant chemotherapy for adenocarcinoma of the esophagogastric junction (aeg). | 2006 | 16543584 |
| [reference values for thyroid 24 hours 123i uptake]. | to establish references for thyroid 24 h 123i uptake value (tuv), we reviewed 475 patients who had free t4 and tsh dosages, and tuv measured 24h after the administration of 123i. the patients were separated in 3 groups: hyperthyroid, euthyroid and hypothyroid, according to thyroid hormone results. the mean and standard deviation (sd) of the tuvs were calculated for each group. we used the unpaired t test to compare the means and roc curves to evaluate the best tuv to separate the groups. the mea ... | 2006 | 16543998 |
| amiodarone-induced thyroid dysfunction in a tertiary center in south brazil. | amiodarone, used in the treatment of cardiac arrhythmias, is associated with thyroid dysfunction. no reports exist on its frequency in southern brazil, nor studies evaluating the usefulness of clinical scores to diagnose thyroid abnormalities in these patients. this study aimed at determining the prevalence of amiodarone-induced thyroid dysfunction in a representative sample from a tertiary center, to study the conditions associated to this dysfunction and to evaluate the reliability of clinical ... | 2006 | 16544014 |
| [detection of subclinical hypothyroidism in pregnant women with different gestational ages]. | to detect subclinical hypothyroidism in pregnant women. | 2006 | 16544015 |
| [introduction of laparoscopy in the treatment of rectal cancer in a coloproctology unit]. | the application of the laparoscopic approach to the treatment of rectal cancer is controversial. the aim of the present study was to evaluate whether the introduction of this technique in a coloproctology unit modified the quality of rectal cancer surgery. | 2006 | 16545282 |