Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| the isolation and characterization of stenotrophomonas maltophilia t4-like bacteriophage dlp6. | increasing isolation of the extremely antibiotic resistant bacterium stenotrophomonas maltophilia has caused alarm worldwide due to the limited treatment options available. a potential treatment option for fighting this bacterium is 'phage therapy', the clinical application of bacteriophages to selectively kill bacteria. bacteriophage dlp6 (vb_smom-dlp6) was isolated from a soil sample using clinical isolate s. maltophilia strain d1571 as host. host range analysis of phage dlp6 against 27 clinic ... | 2017 | 28291834 |
| association between glucose intolerance and bacterial colonisation in an adult population with cystic fibrosis, emergence of stenotrophomonas maltophilia. | diabetes is common in cystic fibrosis (cf). glucose can be detected in the airway when the blood glucose is elevated, which favours bacterial growth. we investigated the relationship between dysglycemia and lung pathogens in cf. | 2017 | 28284526 |
| stenotrophomonas maltophilia: an emerging pathogen in paediatric population. | stenotrophomonas maltophilia (formerly pseudomonas maltophilia/xanthomonas maltophilia), a gram- negative, non-fermenting bacillus, is being increasingly recognized as a threatening nosocomial pathogen, associated with significant mortality. | 2017 | 28273966 |
| stenotrophomonas maltophilia isolated from prostatic fluid as an infertility factor in a male dog. | the aim of this case was to describe very rare infection of canine prostate gland with stenotrophomonas maltophilia which had influence on male fertility. the bacterium was cultured from third fraction of the ejaculate collected by manual manipulation. the sperm concentration and motility parameters were evaluated by hamilton-thorne sperm analyser, version ivos 12.3, sperm morphology by diff-quick staining and live/dead spermatozoa by eosin/nigrosin staining. after 3 weeks of treatment with targ ... | 2017 | 28261845 |
| evaluation of trimethoprim-sulfamethoxazole based combination therapy against stenotrophomonas maltophilia: in vitro effects and clinical efficacy in cancer patients. | the aim of this study was to evaluate the in vitro effects and clinical efficacies of trimethoprim-sulfamethoxazole (sxt) combined with other antimicrobial agents against stenotrophomonas maltophilia. | 2017 | 28257816 |
| comparison of biochemical properties of the original and newly identified oleate hydratases from stenotrophomonas maltophilia. | oleate hydratases (ohyas) catalyze the conversion of unsaturated fatty acids to 10-hydroxy fatty acids, which are used as precursors of important industrial compounds, including lactones, and ω-hydroxycarboxylic and α,ω-dicarboxylic acids. the genes encoding ohya and a putative fatty acid hydratase in stenotrophomonas maltophilia were identified by genomic analysis. the putative fatty acid hydratase was purified and identified as an oleate hydratase (ohya2) based on its substrate specificity. th ... | 2017 | 28235876 |
| vitamin k3 induces the expression of the stenotrophomonas maltophilia smevwx multidrug efflux pump. | stenotrophomonas maltophilia is an opportunistic pathogen, with increasing prevalence, able to cause infections in immunocompromised patients or in those with a previous pathology. the treatment of the infections caused by this bacterium is often complicated due to the several intrinsic antibiotic resistance mechanisms that it presents. multidrug efflux pumps are among the best studied mechanisms of s. maltophilia antibiotic resistance. some of these efflux pumps have a basal expression level bu ... | 2017 | 28223380 |
| metagenome-assembled draft genome sequence of a novel microbial stenotrophomonas maltophilia strain isolated from caenorhabditisremanei tissue. | stenotrophomonas maltophilia is a gram-negative aerobic bacterium and emerging nosocomial pathogen. here, we present a draft genome sequence for an s. maltophilia strain assembled from a metagenomic dna extract isolated from a laboratory stock of the nematode worm caenorhabditis remanei. | 2017 | 28209833 |
| overexpression of smedef efflux pump decreases aminoglycoside resistance in stenotrophomonas maltophilia. | the smedef pump of stenotrophomonas maltophilia is negatively regulated by smet. strains kjδt (smet deletion mutant) and kjt-d(m) (mutant with defective smet-binding site) showed increased resistance to chloramphenicol/nalidixic acid/macrolides and susceptibility to aminoglycoside. overexpression of the smedef pump, in either kjδt or kjt-d(m), downregulated smeyz expression, which is responsible for the reduced aminoglycoside resistance. furthermore, the smerysy two-component regulatory system w ... | 2017 | 28193669 |
| inhibitory activity and chemical characterization of daucus carota subsp. maximus essential oils. | the essential oils (eos) of green seeds from daucus carota subsp. maximus growing wild in pantelleria island (sicily, italy) were characterised. eos were extracted by steam distillation, examined for their inhibitory properties against food-borne gram positive and gram negative bacteria and analysed for the chemical composition by gas chromatography (gc) and mass spectrometry (ms). undiluted eos showed a large inhibition spectrum against gram positive strains and also vs acinetobacter spp. and s ... | 2017 | 28171692 |
| jacquet erosive diaper dermatitis with stenotrophomonas maltophilia colonization. | 2017 | 28166618 | |
| global and local selection acting on the pathogen stenotrophomonas maltophilia in the human lung. | bacterial populations diversify during infection into distinct subpopulations that coexist within the human body. yet, it is unknown to what extent subpopulations adapt to location-specific selective pressures as they migrate and evolve across space. here we identify bacterial genes under local and global selection by testing for spatial co-occurrence of adaptive mutations. we sequence 552 genomes of the pathogen stenotrophomonas maltophilia across 23 sites of the lungs from a patient with cysti ... | 2017 | 28102223 |
| clinical characteristics of stenotrophomonas maltophilia bacteremia: a regional report and a review of a japanese case series. | objective stenotrophomonas maltophilia is an emerging nosocomial pathogen that causes fatal infections in critically ill or immunocompromised patients. s. maltophilia bacteremia (smb) is a rare condition, and its clinical characteristics in japanese settings are not well known. methods the medical charts of patients with smb were retrospectively reviewed at two medical facilities (okayama university hospital and tsuyama chuo hospital) for seven years. the data were analyzed along with those prev ... | 2017 | 28090041 |
| the impact of carbapenem resistance on clinical deterioration and mortality in patients with liver disease. | infections with multidrug-resistant gram-negative bacteria are significantly impairing the prognosis of patients with liver disease. in particular, carbapenem resistance further narrows therapeutic options. this study investigates the impact of carbapenem-resistant gram-negative bacteria on the outcome of patients with liver disease and cirrhosis. | 2017 | 28374901 |
| emergence of carbapenem resistant non-fermenting gram-negative bacilli isolated in an icu of a tertiary care hospital. | the emergence and spread of multi-drug resistant (mdr) non-fermenting gram-negative bacilli (nfgnb) in intensive care units (icu) and their genetic potential to transmit diverse antibiotic resistance regardless of their ability to ferment glucose poses a major threat in hospitals. the complex interplay of clonal spread, persistence, transmission of resistance elements and cell-cell interaction leads to the difficulty in controlling infections caused by these multi drug-resistant strains. among n ... | 2017 | 28273965 |
| the expanding role of type ii secretion in bacterial pathogenesis and beyond. | type ii secretion (t2s) is one means by which gram-negative pathogens secrete proteins into the extracellular milieu and/or host organisms. based upon recent genome sequencing, it is clear that t2s is largely restricted to the proteobacteria, occurring in many, but not all genera in the α-, β-, γ-, and δ- classes. prominent human and/or animal pathogens that express a t2s system(s) include acinetobacter baumannii, burkholderia pseudomallei, chlamydia trachomatis, escherichia coli, klebsiella pne ... | 2017 | 28264910 |
| non-fermentative gram-negative rods bacteremia in children with cancer: a 14-year single-center experience. | data on non-fermentative gram-negative rods (nfgnr) bacteremia in children with malignancies are limited. the aim of this study was to present clinical picture, antimicrobial susceptibility pattern, risk factors for resistance and outcome in nfgnr bacteremia in children with cancer. | 2017 | 28205160 |
| biocidal efficacy of multipurpose solutions against gram-negative organisms associated with corneal infiltrative events. | because corneal infiltrative events (cies) may result from bacterial components on contact lenses, which can come from contaminated lens cases, we evaluated the biocidal efficacy of five multipurpose solutions against gram-negative commonly isolated and cie-associated organisms. | 2017 | 28194876 |
| nosocomial infections with imp-19-producing pseudomonas aeruginosa linked to contaminated sinks, france. | we isolated imp-19-producing pseudomonas aeruginosa from 7 patients with nosocomial infections linked to contaminated sinks in france. we showed that blaimp-19 was located on various class 1 integrons among 8 species of gram-negative bacilli detected in sinks: p. aeruginosa, achromobacter xylosoxidans, a. aegrifaciens, p. putida, stenotrophomonas maltophilia, p. mendocina, comamonas testosteroni, and sphingomonas sp. | 2017 | 28098548 |
| in vitro activity of ceftolozane-tazobactam against multidrug-resistant nonfermenting gram-negative bacilli isolated from patients with cystic fibrosis. | ceftolozane-tazobactam was tested against 58 multidrug-resistant nonfermenting gram-negative bacilli (35 pseudomonas aeruginosa, 11 achromobacter xylosoxydans, and 12 stenotrophomonas maltophilia isolates) isolated from cystic fibrosis patients and was compared to ceftolozane alone, ceftazidime, meropenem, and piperacillin-tazobactam. ceftolozane-tazobactam was the most active agent against p. aeruginosa but was inactive against a. xylosoxydans and s. maltophilia in time-kill experiments, ceftol ... | 2017 | 28096165 |
| performance of vitek 2 for antimicrobial susceptibility testing of acinetobacter baumannii, pseudomonas aeruginosa, and stenotrophomonas maltophilia with vitek 2 (2009 fda) and clsi m100s 26th edition breakpoints. | the performances of vitek 2 ast-gn69 and ast-xn06 cards were compared to clinical and laboratory standards institute (clsi) reference broth microdilution (bmd) for 99 isolates of pseudomonas aeruginosa, 26 acinetobacter baumannii isolates, and 11 stenotrophomonas maltophilia isolates. in total, 15 antimicrobials were evaluated, with 11 for p. aeruginosa, 14 for a. baumannii, and 2 for s. maltophilia categorical agreement (ca) was assessed using both vitek 2 breakpoints and 2016 clsi m100s 26th e ... | 2017 | 27881616 |
| determinants of antibacterial spectrum and resistance potential of the elongation factor g inhibitor argyrin b in key gram-negative pathogens. | argyrins are natural products with antibacterial activity against gram-negative pathogens, such as pseudomonas aeruginosa, burkholderia multivorans, and stenotrophomonas maltophilia we previously showed that argyrin b targets elongation factor g (fusa). here, we show that argyrin b activity against p. aeruginosa pao1 (mic = 8 μg/ml) was not affected by deletion of the mexab-oprm, mexxy-oprm, mexcd-oprj, or mexef-oprn efflux pump. however, argyrin b induced expression of mexxy, causing slight but ... | 2017 | 28096160 |
| synthetic peptides derived from bovine lactoferricin exhibit antimicrobial activity against e. coli atcc 11775, s. maltophilia atcc 13636 and s. enteritidis atcc 13076. | linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin b-containing non-natural amino acids and the rwqwr motif were synthesized, purified, and characterized using rp-hplc, maldi-tof mass spectrometry, and circular dichroism. the antibacterial activity of peptides against escherichia coli atcc 11775, stenotrophomonas maltophilia atcc 13636, and salmonella enteritidis atcc 13076 was evaluated. the minimum inhibitory concentration (mic) and minimum bactericidal concentration ( ... | 2017 | 28287494 |
| in vitro antibacterial activity of mgdg-palmitoyl from oscillatoria acuminata ntapc05 against extended-spectrum β-lactamase producers. | extended-spectrum β-lactamase (esbl)-producing bacteria pose a big challenge in clinical practices, warranting a new therapeutic strategy. in this study, methanol extract of the marine cyanobacterium oscillatoria acuminata ntapc05 was fractionated under bioassay guidance and the fractions were tested against three well-characterized esbl-producing bacteria escherichia coli u655, stenotrophomonas maltophilia b929 and enterobacter asburiae b938. out of the four hplc fractions, fraction 2 showed ba ... | 2017 | 28377637 |
| potency and selectivity indices of acetone leaf extracts of nine selected south african trees against six opportunistic enterobacteriaceae isolates from commercial chicken eggs. | the rise in antimicrobial resistance in a plethora of nosocomial and opportunistic bacterial pathogens often isolated from commercial eggs, poses a serious public health concern. the existence of these contaminants may also serve as a drawback in the current efforts of improving the well-being of immunocompromised patients. the aim of this study was to determine the efficacy of plant extracts that had good activity on escherichia coli in previous word on pathogens isolated from eggs for possible ... | 2017 | 28148263 |
| risk of infection transmission in curvilinear array echoendoscopes: results of a prospective reprocessing and culture registry. | the complex design of the elevator mechanism in duodenoscopes has been recognized as a challenge for disinfection and recently implicated as a potential source of persistent bacterial contamination. curvilinear array (cla) echoendoscopes also have an elevator mechanism; however, there are no recommendations or data regarding the risk of persistent bacterial contamination of echoendoscopes. here we hoped to determine the yield of microbial growth with routine bacterial surveillance cultures of re ... | 2017 | 27478029 |
| simplified and representative bacterial community of maize roots. | plant-associated microbes are important for the growth and health of their hosts. as a result of numerous prior studies, we know that host genotypes and abiotic factors influence the composition of plant microbiomes. however, the high complexity of these communities challenges detailed studies to define experimentally the mechanisms underlying the dynamics of community assembly and the beneficial effects of such microbiomes on plant hosts. in this work, from the distinctive microbiota assembled ... | 2017 | 28275097 |
| copper-tolerant rhizosphere bacteria-characterization and assessment of plant growth promoting factors. | remediation of heavy metal contaminated soil is a major problem or concern worldwide. heavy metal accumulation in the soil is increasing day by day by industries, mines, agriculture, fuel combustion and municipal waste discharge. such contaminated soils harbour a large number of resistant microbial populations. screening and isolation of such microbes would be utilized for natural remediation of metal contaminated soils. therefore, in the present study, highly copper-tolerant bacteria from rhizo ... | 2017 | 28251535 |
| coexistence of free-living amoebae and bacteria in selected south african hospital water distribution systems. | pathogenic free-living amoebae (fla), such as naegleria fowleri, balamuthia mandrillaris and acanthamoeba species isolated from aquatic environments have been implicated in central nervous system, eye and skin human infections. they also allow the survival, growth and transmission of bacteria such as legionella, mycobacteria and vibrio species in water systems. the purpose of this study was to investigate the co-occurrence of potentially pathogenic fla and their associated bacteria in hospital w ... | 2017 | 27730363 |
| antimicrobial activity of tigecycline and cefoperazone/sulbactam tested against 18,386 gram-negative organisms from europe and the asia-pacific region (2013-2014). | a total of 18,386 organisms, including 13,224 enterobacteriaceae, 3536 pseudomonas aeruginosa, 1254 acinetobacter spp., and 372stenotrophomonas maltophilia were collected from western europe (weu; n=10,021), eastern europe (eeu; n=4957), and the asia-pacific region (apac; n=3408 [1052 from china]) in 2013-2014 as part of the sentry antimicrobial surveillance program and tested by a reference broth microdilution method for susceptibility against tigecycline, cefoperazone/sulbactam, and comparator ... | 2017 | 28341098 |
| paediatric infectious keratitis: a case series of 107 children presenting to a tertiary referral centre. | corneal ulcers can result in severe visual impairment in children. the recent trends of paediatric microbial ulcerative keratitis in the usa are unknown. the purpose of this study is to report the risk factors, microbiological profile and treatment outcomes of paediatric microbial keratitis in south florida. | 2017 | 28298316 |
| bacterial competition and quorum-sensing signalling shape the eco-evolutionary outcomes of model in vitro phage therapy. | the rapid rise of antibiotic resistance has renewed interest in phage therapy - the use of bacteria-specific viruses (phages) to treat bacterial infections. even though phages are often pathogen-specific, little is known about the efficiency and eco-evolutionary outcomes of phage therapy in polymicrobial infections. we studied this experimentally by exposing both quorum-sensing (qs) signalling pao1 and qs-deficient lasr pseudomonas aeruginosa genotypes (differing in their ability to signal intra ... | 2017 | 28127392 |
| fluorescent probe based subcellular distribution of cu(ii) ions in living electrotrophs isolated from cu(ii)-reduced biocathodes of microbial fuel cells. | based on the four indigenous electrotrophs (stenotrophomonas maltophilia jy1, citrobacter sp. jy3, pseudomonas aeruginosa jy5 and stenotrophomonas sp. jy6) isolated from well adapted cu(ii)-reduced biocathodes of microbial fuel cells (mfcs), a rhodamine based cu(ii) fluorescent probe was used to imaginably and quantitatively track subcellular cu(ii) ions in these electrotrophs. cathodic electrons led to more cu(ii) ions (14.3-30.1%) in the intracellular sites at operation time of 2-3h with cu(ii ... | 2017 | 27907871 |
| correlation between circuital current, cu(ii) reduction and cellular electron transfer in eab isolated from cu(ii)-reduced biocathodes of microbial fuel cells. | the performance of four indigenous electrochemically active bacteria (eab) (stenotrophomonas maltophilia jy1, citrobacter sp. jy3, pseudomonas aeruginosa jy5 and stenotrophomonas sp. jy6) was evaluated for cu(ii) reduction on the cathodes of microbial fuel cells (mfcs). these eab were isolated from well adapted mixed cultures on the mfc cathodes operated for cu(ii) reduction. the relationship between circuital current, cu(ii) reduction rate, and cellular electron transfer processes was investiga ... | 2017 | 27835761 |
| pulmonary exacerbation due to colistin-resistant stenotrophomonas maltophilia in a bulgarian cystic fibrosis patient. | in patients with cystic fibrosis (cf) lung damage secondary to chronic infection is the main cause of death. treatment of lung disease to reduce the impact of infection, inflammation and subsequent lung injury is therefore of major importance. as pseudomonas aeruginosa is the dominant pathogen in cf patients it has been the major target of all treatment strategies, possible antibiotic regimens and recommendations for years. more sophisticated antibiotic therapies introduced over the last decades ... | 2017 | 27552791 |
| increasing incidence of multidrug resistance among cystic fibrosis respiratory bacterial isolates. | pseudomonas aeruginosa and staphylococcus aureus are common pathogens in cystic fibrosis (cf) patients with increasing multidrug resistance (mdr). this study characterized antimicrobial susceptibility trends among organisms isolated from the respiratory tract of cf patients. microbiological culture and sensitivity results for all cf patients were collected from january 2010 through december 2014. minimum inhibitory concentrations were obtained using phoenix(®) and etest(®) methods. clinical and ... | 2017 | 27326758 |
| organoselenium polymer inhibits biofilm formation in polypropylene contact lens case material. | contact lens-acquired bacterial infections are a serious problem. of the reported cases, inadequate cleaning of the lens case was the most common cause of lens contamination. organoselenium has been shown to inhibit bacterial attachment to different polymer materials. this study evaluates the ability of an organoselenium monomer, incorporated into the polymer of a polypropylene contact lens case coupon, to block the formation of biofilms in a lens case. | 2017 | 26974534 |
| air pollution exposure is associated with mrsa acquisition in young u.s. children with cystic fibrosis. | the role of air pollution in increasing susceptibility to respiratory tract infections in the cystic fibrosis (cf) population has not been well described. we recently demonstrated that chronic pm2.5 exposure is associated with an increased risk of initial pseudomonas aeruginosa acquisition in young children with cf. the purpose of this study was to determine whether pm2.5 exposure is a risk factor for acquisition of other respiratory pathogens in young children with cf. | 2017 | 28750627 |
| seasonality of acquisition of respiratory bacterial pathogens in young children with cystic fibrosis. | seasonal variations are often observed for respiratory tract infections; however, limited information is available regarding seasonal patterns of acquisition of common cystic fibrosis (cf)-related respiratory pathogens. we previously reported differential seasonal acquisition of pseudomonas aeruginosa in young children with cf and no such variation for methicillin-susceptible staphylococcus aureus acquisition. the purpose of this study was to describe and compare the seasonal incidence of acquis ... | 2017 | 28599639 |
| [distribution and drug resistance of pathogens at hematology department of jiangsu province from 2014 to 2015: results from a multicenter, retrospective study]. | objective: to describe the distribution and drug resistance of pathogens at hematology department of jiangsu province from 2014 to 2015 to provide reference for empirical anti-infection treatment. methods: pathogens were from hematology department of 26 tertiary hospitals in jiangsu province from 2014 to 2015. antimicrobial susceptibility testing was carried out according to a unified protocol using kirby-bauer method or agar dilution method. collection of drug susceptibility results and corresp ... | 2017 | 28810329 |
| in vitro activity of the siderophore cephalosporin, cefiderocol, against a recent collection of clinically relevant gram-negative bacilli from north america and europe, including carbapenem-nonsusceptible isolates (sidero-wt-2014 study). | cefiderocol (formerly s-649266) is an investigational siderophore cephalosporin. iron-depleted cation-adjusted mueller-hinton broth (id-camhb) was prepared according to the clinical and laboratory standards institute (clsi) protocol and used to perform broth microdilution testing of cefiderocol against a 2014-2015 collection of clinical isolates of gram-negative bacilli from north america (n = 4,239) and europe (n = 4,966). the concentrations of cefiderocol inhibiting 90% of isolates tested (mic ... | 2017 | 28630181 |
| a genoproteomic approach to detect peptide markers of bacterial respiratory pathogens. | rapid identification of respiratory pathogens may facilitate targeted antimicrobial therapy. direct identification of bacteria in bronchoalveolar lavage (bal) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry is confounded by interfering substances. we describe a method to identify unique peptide markers of 5 gram-negative bacteria by liquid chromatography-tandem mass spectrometry (lc-ms/ms) for direct pathogen identification in bal. | 2017 | 28588123 |
| [analysis of the spectrum and resistance of pathogen causing sepsis in patients with severe acute pancreatitis]. | objective: to investigate the characteristics of spectrum and drug resistance of pathogens causing sepsis in patients with severe acute pancreatitis(sap). methods: the clinical data of 63 sap patients with sepsis admitted in department of hepatobiliary, people's liberation army general hospital from january 2014 to december 2015 were retrospectively studied. there were 47 males and 16 females, aged from 22 to 73 years, with an average age of (52±11)years. samples were collected mainly from: (1)p ... | 2017 | 28464580 |
| in vitro activity of cefepime/zidebactam (wck 5222) against gram-negative bacteria. | diazabicyclooctanes (dbos) inhibit class a, class c and some class d β-lactamases. a few also bind pbp2, conferring direct antibacterial activity and a β-lactamase-independent 'enhancer' effect, potentiating β-lactams targeting pbp3. we tested a novel dbo, zidebactam, combined with cefepime. | 2017 | 28158732 |
| using phenotype microarrays in the assessment of the antibiotic susceptibility profile of bacteria isolated from wastewater in on-site treatment facilities. | the scope of the study was to apply phenotype biolog microarray (pm) technology to test the antibiotic sensitivity of the bacterial strains isolated from on-site wastewater treatment facilities. in the first step of the study, the percentage values of resistant bacteria from total heterotrophic bacteria growing on solid media supplemented with various antibiotics were determined. in the untreated wastewater, the average shares of kanamycin-, streptomycin-, and tetracycline-resistant bacteria wer ... | 2017 | 28451946 |
| an assessment on the role of endophytic microbes in the therapeutic potential of fagonia indica. | natural products of animals, plants and microbes are potential source of important chemical compounds, with diverse applications including therapeutics. endophytic bacteria that are especially associated with medicinal plants presents a reservoir of therapeutic compounds. fagonia indica has been recently investigated by numerous researchers because of its striking therapeutic potential especially in cancer. it is also reported that endophytes play a vital role in the biosynthesis of various meta ... | 2017 | 28764775 |
| antibiotic susceptibility pattern of burkholderia cepacia complex and stenotrophomonas maltophilia: a 5-year analysis. | 2017 | 28681835 | |
| bacterial bloodstream infections in a tertiary infectious diseases hospital in northern vietnam: aetiology, drug resistance, and treatment outcome. | bloodstream infections (bsis) are associated with high morbidity and mortality worldwide. however their aetiology, antimicrobial susceptibilities and associated outcomes differ between developed and developing countries. systematic data from vietnam are scarce. here we present aetiologic data on bsi in adults admitted to a large tertiary referral hospital for infectious diseases in hanoi, vietnam. | 2017 | 28701159 |