Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| impairment of circulating endothelial progenitors in down syndrome. | pathological angiogenesis represents a critical issue in the progression of many diseases. down syndrome is postulated to be a systemic anti-angiogenesis disease model, possibly due to increased expression of anti-angiogenic regulators on chromosome 21. the aim of our study was to elucidate some features of circulating endothelial progenitor cells in the context of this syndrome. | 2010 | 20836844 |
| [treatment of human infections caused by bartonella spp.]. | infections by bartonella spp. include a wide spectrum of emerging and re-emerging infectious diseases. there is not a universal therapy for this infection, therefore treatment should be chosen individually. the aim of this review is to update the therapeutics aspects of this kind of infections. | 2010 | 20844840 |
| a first japanese case of bartonella henselae-induced endocarditis diagnosed by prolonged culture of a specimen from the excised valve. | bartonella henselae, the causative agent of cat scratch disease, is increasingly recognized as a cause of culture-negative endocarditis. this report describes the first japanese case, which was diagnosed after a prolonged culture of the excised aortic valve. high igg and igm titers to b. henselae pointed to a subacute course of the disease. | 2010 | 20846591 |
| prevalence of select infectious agents in inflammatory aural and nasopharyngeal polyps from client-owned cats. | benign, inflammatory polyps may affect the nasopharynx and auditory canal of cats. it has been proposed that inflammation induced by infectious disease agents could trigger polyp formation. the objective of this pilot study was to determine the prevalence of feline herpesvirus-1 (fhv-1), feline calicivirus (fcv), mycoplasma species, bartonella species and chlamydophila felis nucleic acids in polyp tissues collected from 30 clinically affected cats. samples collected from the tympanic bulla from ... | 2010 | 20850367 |
| evidence of transfer by conjugation of type iv secretion system genes between bartonella species and rhizobium radiobacter in amoeba. | bartonella species cospeciate with mammals and live within erythrocytes. even in these specific niches, it has been recently suggested by bioinformatic analysis of full genome sequences that lateral gene transfer (lgt) may occur but this has never been demonstrated biologically. here we describe the sequence of the b. rattaustraliani (aust/nh4(t)) circular plasmid (pnh4) that encodes the tra cluster of the type iv secretion system (t4ss) and we eventually provide evidence that bartonella species ... | 2010 | 20856925 |
| combined mlst and aflp typing of bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution. | bartonella species are gram-negative, fastidious bacteria. bartonella henselae is found in cats and transmitted to humans via cat scratches or bites causing cat-scratch disease, characterized by clinical symptoms with varying severity. the prevalence of bartonellosis among humans in germany appears to be high, and severe clinical cases have been described. however, epidemiological data of b. henselae in cats are rare. in this study we determined the detection rates of bartonella ssp. in cats by ... | 2010 | 20863631 |
| rats as indicators of the presence and dispersal of six zoonotic microbial agents in cyprus, an island ecosystem: a seroepidemiological study. | a total of 622 rats (402 rattus norvegicus and 220 r. rattus frugivorus) were collected in 51 different areas in cyprus during 2000-2003 and used as indicators of the presence and dispersal of six zoonotic microbial agents. igg antibodies against rickettsia typhi (241/496, 48.6%), r. conorii (209/500, 41.8%), toxoplasma sp. (138/494, 27.9%), coxiella burnetti (63/494, 12.8%), bartonella henselae (52/494, 10.5%) and leishmania infantum (36/494, 7.3%) were detected by indirect immunofluorescence t ... | 2010 | 20870259 |
| multi-locus sequence analysis reveals host specific association between bartonella washoensis and squirrels. | to clarify phylogenetic relationships and genetic diversity among bartonella washoensis strains obtained from squirrels, multi-locus sequence analysis (mlsa) with the 16s rrna, ftsz, glta, groel, ribc, and rpob genes was applied for 20 strains of b. washoensis isolated from five genera of squirrels (tamias, tamiasciurus, glaucomys, sciurus, and spermophilus) within the family sciuridae. sequence similarities in the concatenated sequences of b. washoensis strains from squirrels of different gener ... | 2010 | 20884133 |
| pathogens and symbionts in ticks: a survey on tick species distribution and presence of tick-transmitted micro-organisms in sardinia, italy. | a total of 1485 adult ticks were collected from mammalian hosts in south-eastern sardinia, italy, during the years 2007-2008. ticks were identified and tested by pcr analysis for presence of rickettsia species of the spotted fever group, ehrlichia canis, anaplasma phagocytophilum, coxiella burnetii, bartonella species and leishmania species. among all tick species examined (rhipicephalus sanguineus, rhipicephalus turanicus, rhipicephalus bursa, rhipicephalus pusillus, hyalomma marginatum margina ... | 2010 | 20884769 |
| bartonella species in small mammals and their ectoparasites in taiwan. | bartonella spp. prevalence in small mammals and their ectoparasites was investigated in taiwan. blood samples were obtained from 66 rats, 20 shrews, 276 mites (laelaps spp.), 74 fleas (xenopsylla cheopis), 81 lice (polyplax spp.), and 47 ticks (41 dermacentor spp. and 6 ixodes spp.). bartonellae were isolated or detected in 27 (31.4%) animals. bartonella dna was detected in 48 (64.9%) fleas and 11 (64.7%) pooled lice samples, but not in mite and tick samples. bartonella phoceensis, b. queensland ... | 2010 | 20889892 |
| cat scratch disease and arthropod vectors: more to it than a scratch? | cat scratch disease is a common infection, particularly in children, and clinicians need to be aware of its potential transmission to humans by arthropod vectors such as fleas and ticks in addition to animal bites and scratches. the absence of a vertebrate bite or scratch does not preclude infection with bartonella henselae. | 2010 | 20823366 |
| [neuroretinitis in cat scratch disease]. | purpose: to present two cases of neuroretinitis in cat scratch disease we present two girls treated in department of ophthalmology of poznai university of medical sciences because of unilateral, painless decrease of vision. both patients presented following cat exposure fever and lymph nodes swelling. ophthalmoscopic findings was neuroretinitis (optic disc edema with the macular star). bartonella henselae antibody titers (igg) were elevated. csd is usually self-limited infection in immunocompete ... | 2010 | 20825068 |
| skin diseases associated with bartonella infection: facts and controversies. | the genus bartonella is composed of a series of species and subspecies. ten of them are responsible for human infections. the best-identified diseases are cat scratch disease (b henselae and possibly b clarridgeiae), trench fever (b quintana), bacillary angiomatosis (b quintana and b henselae), and the spectrum of verruga peruana, carrion disease, and oroya fever (b bacilliformis). controversies exist about the implication of a few other microorganisms being involved in these diseases. several o ... | 2010 | 20797506 |
| bartonella genotypes in fleas (insecta: siphonaptera) collected from rodents in the negev desert, israel. | fleas collected from rodents in the negev desert in southern israel were molecularly screened for bartonella species. a total of 1,148 fleas, collected from 122 rodents belonging to six species, were pooled in 245 pools based on flea species, sex, and rodent host species. two bartonella gene fragments, corresponding to rna polymerase b (rpob) and citrate synthase (glta), were targeted, and 94 and 74 flea pools were found positive by pcr, respectively. the bartonella 16s-23s internal transcribed ... | 2010 | 20802081 |
| [traveler's fever associated with cervical adenomegaly and antibodies for bartonella sp in a brazilian patient returning from south africa]. | a large number of travelers visit the african continent annually for studying, tourism or business reasons. the authors report a case of cervical adenomegaly, hepatomegaly and splenomegaly associated with a two-week history of fever and seropositivity for bartonella sp in a 22-year-old female patient who returned from south africa after field work with primates in a wild area. | 2010 | 20802956 |
| bartonella species, feline herpesvirus-1, and toxoplasma gondii pcr assay results from blood and aqueous humor samples from 104 cats with naturally occurring endogenous uveitis. | toxoplasma gondii, bartonella henselae and feline herpesvirus-1 (fhv-1) have been implicated as causative agents in feline uveitis. the usefulness of serum and aqueous humor (ah) antibody testing for these agents is limited as antibodies can be detected in both healthy cats and cats with uveitis. very few studies using polymerase chain reaction (pcr) assays to amplify organism dna from samples from cats with uveitis have been performed. in this study, assays to detect t gondii antibodies, feline ... | 2010 | 20817587 |
| improved detection of bartonella dna in mammalian hosts and arthropod vectors by real-time pcr using the nadh dehydrogenase gamma subunit (nuog). | we used a whole-genome scanning technique to identify the nadh dehydrogenase gamma subunit (nuog) primer set that is sensitive and specific enough to detect a diverse number of bartonella species in a wide range of environmental samples yet maintains minimal cross-reactivity to mammalian host and arthropod vector organisms. | 2010 | 20926707 |
| microbiology. interacting parasites. | 2010 | 20929765 | |
| species interactions in a parasite community drive infection risk in a wildlife population. | most hosts, including humans, are simultaneously or sequentially infected with several parasites. a key question is whether patterns of coinfection arise because infection by one parasite species affects susceptibility to others or because of inherent differences between hosts. we used time-series data from individual hosts in natural populations to analyze patterns of infection risk for a microparasite community, detecting large positive and negative effects of other infections. patterns remain ... | 2010 | 20929776 |
| feline bartonellosis. | bartonella infection is common among domestic cats, but the role of bartonella species as feline pathogens requires further study. most bartonella species that infect cats are zoonotic. cats are the mammalian reservoir and vector for bartonella henselae, an important zoonotic agent. cat fleas transmit bartonella among cats, and cats with fleas are an important source of human b henselae infections. new information about bartonella as feline pathogens has recently been published, and this article ... | 2010 | 20933137 |
| variability of bartonella genotypes among small mammals in spain. | in order to study which bartonella genotypes are circulating among small mammals in spain, we analyzed the spleens of 395 animals from three different areas-247 animals from the basque country (northern spain), 121 animals from catalonia (northeastern spain), and 27 animals from madrid (central spain)-by a triplex pcr combined with a reverse line blot previously described by our group. the prevalence of bartonella was 26.8% (106/395), and in 4.8% (19/395) of the animals more than one bartonella ... | 2010 | 20935117 |
| [cat-scratch disease]. | 2010 | 20942049 | |
| refractory bartonella quintana bacillary angiomatosis following chemotherapy for chronic lymphocytic leukaemia. | bacillary angiomatosis is a well-recognized infection with cutaneous and systemic manifestations caused by bartonella henselae or bartonella quintana and occurs in immunocompromised patients. we report a case of b. quintana bacillary angiomatosis following fludarabine-based chemotherapy for chronic lymphocytic leukaemia that was refractory to standard treatment and was complicated by lymphadenopathy and osteomyelitis. | 2010 | 20947664 |
| isolation of bartonella capreoli from elk. | the aim of the present study was to investigate the presence of bartonella infections in elk populations. we report the isolation of four bartonella strains from 55 elk blood samples. sequencing analysis demonstrated that all four strains belong to bartonella capreoli, a bacterium that was originally described in the wild roe deer of europe. our finding first time demonstrated that b. capreoli has a wide geographic range, and that elk may be another host for this bacterium. further investigation ... | 2010 | 20961711 |
| combined action of the type iv secretion effector proteins bepc and bepf promotes invasome formation of bartonella henselae on endothelial and epithelial cells. | bartonella henselae (bhe) can invade human endothelial cells (ecs) by two distinguishable entry routes: either individually by endocytosis or as large bacterial aggregates by invasome-mediated internalization. only the latter process is dependent on a functional virb/vird4 type iv secretion system (t4ss) and the thereby translocated bep effector proteins. here, we introduce hela cells as a new cell system suitable to study invasome formation. we describe a novel route to trigger invasome formati ... | 2010 | 20964799 |
| bartonella henselae and the potential for arthropod vector-borne transmission. | abstract introduction: bartonella henselae, the causative agent of the illness referred to as cat scratch disease, is a common infection, particularly in children, and clinicians need to be aware of its potential transmission to humans by arthropod vectors such as fleas and ticks in addition to animal bites and scratches. the absence of a vertebrate bite or scratch does not preclude infection with b. henselae. materials and methods: literature regarding arthropod transmission of b. henselae was ... | 2010 | 20973657 |
| cardiac troponin-i concentrations in dogs with bradyarrhythmias before and after artificial pacing. | to quantify cardiac troponin-i (ctni) concentration in dogs with symptomatic bradyarrhythmias before and after artificial pacing and to correlate ctni concentration with diagnosis, echocardiographic parameters, serology, and outcome. | 2010 | 21030328 |
| occlusive vasculitis and optic disk neovascularization associated with neuroretinitis. | to report a case of neuroretinitis associated with ischemic nasal branch retinal vein occlusion, periphlebitis, and neovascularization of the optic disk. | 2010 | 21034304 |
| a comparative study of the interaction of bartonella henselae strains with human endothelial cells. | bartonella henselae can cause a wide range of clinical outcomes and may lead to severe disease, especially in patients with acquired immunodeficiency syndrome. it is well-known that b. henselae-induced cell proliferation is mediated by anti-apoptotic activity; however, the detailed mechanism is still unclear. in this study, the cellular responses of endothelial cells after infection with four b. henselae strains were compared and protein candidates that may be involved in the interaction between ... | 2010 | 21035278 |
| prevalence and genetic diversity of bartonella species detected in different tissues of small mammals in nepal. | bartonellae were detected in a total of 152 (23.7%) of 642 tissues from 108 (48.4%) of 223 small mammals trapped in several urban areas of nepal. based on rpob and glta sequence analyses, genotypes belonging to seven known bartonella species and five genotypes not belonging to previously known species were identified in these animals. | 2010 | 21037303 |
| relevance of feline calicivirus, feline immunodeficiency virus, feline leukemia virus, feline herpesvirus and bartonella henselae in cats with chronic gingivostomatitis. | despite its common occurrence, the aetiology of chronic gingivostomatitis in cats remains uncertain. aetiology is likely multifactorial, and several infectious agents may be associated with chronic gingivostomatitis. the purpose of this study was to investigate the prevalence of feline calicivirus (fcv), feline immunodeficiency virus (fiv), feline leukemia virus (felv), feline herpesvirus (fhv), and bartonella henselae (b. henselae) in cats with chronic gingivostomatitis and in an age-matched co ... | 2010 | 21038808 |
| the bartonella henselae virb/bep system interferes with vascular endothelial growth factor (vegf) signalling in human vascular endothelial cells. | the vasculotropic pathogen bartonella henselae (bh) intimately interacts with human endothelial cells (ecs) and subverts multiple cellular functions. here we report that bh specifically interferes with vascular endothelial growth factor (vegf) signalling in ecs. bh infection abrogated vegf-induced proliferation and wound closure of ec monolayers as well as the capillary-like sprouting of ec spheroids. on the molecular level, bh infection did not alter vegf receptor 2 (vegfr2) expression or cell ... | 2010 | 21044238 |
| [fever of unknown origin and detection of bartonella henselae igg seropositivity: a case report.] | bartonella henselae, is a gram-negative bacterium which causes cat scratch disease (csd) in man. there are sporadic case reports of csd in turkey. cats play an important reservoir role for b.henselae transmission to man. in this report, a cat owner with fever of unknown origin was presented. bartonella spp. was isolated from the blood culture of cat which had chronic progressive gingivostomatitis. b.henselae was identified by amplification of a region of citrate synthase (glta) gene by using pol ... | 2010 | 21064000 |
| prevalence of bartonella species dna and antibodies in cats (felis catus) submitted to a spay/neuter program in rio de janeiro, brazil. | the prevalence of bartonella species dna and antibodies for bartonella henselae were studied in 40 clinically healthy cats (felis catus, linnaeus 1758) submitted to a spay/neuter program in rio de janeiro, brazil. additionally, the prevalence of bartonella species dna was investigated in the fleas found parasitizing the subject cats. for this purpose, blood samples were obtained from all cats, and dna extraction was performed on the blood, and blood clotted samples, as well as on pools of fleas ... | 2010 | 21071251 |
| bacillary angiomatosis with atypical clinical presentation in an immunocompetent patient. | bacillary angiomatosis is a recently described infectious disease that usually affects immunosupressed hosts with a previous history of contact with cats. we report a rare case of bacillary angiomatosis in an immunocompetent 59-year-old woman with no history of previous exposure to cats, and atypical clinical features (fever and subcutaneous nodules with ulceration on the left ankle). histopathology of the lesion showed extensive ulceration and reactive tumor-like vascular proliferation of the b ... | 2010 | 21079313 |
| the occurrence of spotted fever rickettsioses and other tick-borne infections in forest workers in poland. | abstract the presence of antibodies to rickettsia conorii, r. helvetica, r. felis, r. slovaca, r. sibirica, and r. massiliae in sera of 129 forest workers from northeastern and southern poland was assayed by indirect immunofluorescence. previous environmental studies revealed presence of spotted fever group (sfg) rickettsiae in ticks collected from these areas. additionally, the workers were examinated for the presence of antibodies specific to other tick-borne bacteria: anaplasma phagocytophilu ... | 2010 | 21083370 |
| evolution of clinical, haematological and biochemical findings in young dogs naturally infected by vector-borne pathogens. | longitudinal studies evaluating the evolution of clinical, haematological, biochemical findings in young dogs exposed for the first time to multiple vector-borne pathogens have not been reported. with the objective of assessing the evolution of clinical, haematological and biochemical findings, these parameters were serially monitored in naturally infected dogs throughout a 1-year follow-up period. young dogs, infected by vector-borne pathogens based on cytology or polymerase chain reaction, wer ... | 2010 | 21106311 |
| prevalence of bartonella henselae and bartonella clarridgeiae in cats in the south of brazil: a molecular study. | bartonella spp are the causative agent of cat scratch disease in humans. cats are the natural reservoir of these bacteria and may infect humans through scratches, bites or fleas. blood samples from 47 cats aged up to 12 months were collected for this study. all animals were lodged in municipal animal shelters in the vale do sinos region, rio grande do sul, brazil. bartonella spp were detected by genus-specific polymerase chain reaction (pcr) and when the pcr was positive, the species were determ ... | 2010 | 21120356 |
| bartonella spp. in bats, kenya. | we report the presence and diversity of bartonella spp. in bats of 13 insectivorous and frugivorous species collected from various locations across kenya. bartonella isolates were obtained from 23 eidolon helvum, 22 rousettus aegyptiacus, 4 coleura afra, 7 triaenops persicus, 1 hipposideros commersoni, and 49 miniopterus spp. bats. sequence analysis of the citrate synthase gene from the obtained isolates showed a wide assortment of bartonella strains. phylogenetically, isolates clustered in spec ... | 2010 | 21122216 |
| bartonella henselae in skin biopsy specimens of patients with cat-scratch disease. | during the past 2 years, we identified live bartonella henselae in the primary inoculation sites of 3 patients after a cat scratch. although our data are preliminary, we report that a cutaneous swab of the skin lesion from a patient in the early stage of cat-scratch disease can be useful for diagnosis of the infection. | 2010 | 21122232 |
| multispacer typing of bartonella henselae isolates from humans and cats, japan. | to determine genotypic distribution of and relationship between human and cat strains of bartonella henselae,we characterized 56 specimens using multispacer typing (mst). of 13 mst genotypes identified, 12 were grouped into cluster 1. in japan, human infections can be caused by b. henselae strains in cluster 1. | 2010 | 21122238 |
| molecular detection of bartonella alsatica in rabbit fleas, france. | 2010 | 21122251 | |
| bartonella infection: treatment and drug resistance. | bartonella species, which belong to the α-2 subgroup of proteobacteria, are fastidious gram-negative bacteria that are highly adapted to their mammalian host reservoirs. bartonella species are responsible for different clinical conditions affecting humans, including carrion's disease, cat scratch disease, trench fever, bacillary angiomatosis, endocarditis and peliosis hepatis. while some of these diseases can resolve spontaneously without treatment, in other cases, the disease is fatal without a ... | 2010 | 21133691 |
| bartonella infection in shelter cats and dogs and their ectoparasites. | abstract mainly through vector transmission, domestic cats and dogs are infected by several bartonella spp. and represent a large reservoir for human infections. this study investigated the relationship of prevalences of bartonella infection in shelter dogs and cats and various ectoparasite species infesting them (fleas, ticks, and lice). moreover, relationships between bartonella infection and animal gender and age and presence of ectoparasites were analyzed. blood samples were collected from 1 ... | 2010 | 21142966 |
| questing ticks in suburban forest are infected by at least six tick-borne pathogens. | abstract the role of ixodes ricinus ticks in the transmission of pathogens of public health importance such as borrelia burgdorferi s.l. is widely recognized and is suspected in several emerging vector-borne pathogens in europe. here, we assess prevalence rates of several endemic and emerging zoonotic pathogens in tick populations in an area of high human population density in france, to contribute to a risk assessment for potential transmission to humans. pathogen prevalence rates were evaluate ... | 2010 | 21158500 |
| [sero-epidemiologic investigation on tick-borne diseases of humans and domestic animals in zhejiang province.] | objective: to investigate the seroprevalence of tick-borne diseases in humans and domestic animals from rural areas of zhejiang province. methods: anji county, jindong district and tiantai county were selected for samples collection according to their geographic locations and historical prevalence of tick-borne diseases. blood samples of humans and domestic animals were collected in the three sites. an indirect immuno-fluorescent antibody test was used to determine the presence of igg antibodies ... | 2010 | 21162818 |
| comparison of two sampling methods for microbiological evaluation of periodontal disease in cats. | periodontal disease in cats is highly prevalent, and its aetiology is associated to bacteria located in the subgingival microbiota, being porphyromonas sp. the most prevalent genus. the conventional technique to sample the subgingival microbiota is the use of cotton swabs over the mucosa and teeth; however the use of subgingival paper points could improve the bacterial recovery. | 2010 | 21168288 |
| [cat scratch disease associated neuroretinitis: clinical report and review of the literature]. | cat scratch disease is the main clinical presentation of bartonella henselae infection. however, ocular manifestations of bartonellosis occur in about 5 to 10% of the patients, mainly presenting as neuroretinitis, choroiditis or oculoglandular syndrome of parinaud. we describe two patients with documented b. henselae infection and typical ocular compromise. both patients were treated and had a favorable visual outcome. | 2010 | 21186508 |
| comments on the manuscript by bitam et al., 'fleas and flea-borne diseases'. | 2010 | 21193340 | |
| bartonella and babesia infections in cattle and their ticks in taiwan. | bartonella and babesia infections and the association with cattle breed and age as well as tick species infesting selected cattle herds in taiwan were investigated. blood samples were collected from 518 dairy cows and 59 beef cattle on 14 farms and 415 ticks were collected from these animals or in a field. bartonella and babesia species were isolated and/or detected in the cattle blood samples and from a selected subset (n=254) of the ticks either by culture or dna extraction, pcr testing and dn ... | 2010 | 21194750 |
| cat scratch disease presenting as acute mastoiditis. | to present the first published case of cat scratch disease presenting as acute mastoiditis and review the relevant literature to discuss the otolaryngologic manifestations of this disease and its treatment. | 2010 | 21225820 |
| persistent infection or successive reinfection of deer mice with bartonella vinsonii subsp. arupensis. | bartonella infections are common in rodents. from 1994 to 2006, longitudinal studies of a rodent community, consisting mainly of deer mice (peromyscus maniculatus), were conducted in southwestern colorado to study hantaviruses. blood samples from deer mice captured one or more times during the period 2003 to 2006 (n = 737) were selected to study bartonellae in deer mice. bartonellae were found to be widely distributed in that population, with an overall prevalence of 82.4% (607/737 mice). no cor ... | 2011 | 21239553 |
| cat-scratch disease. | cat-scratch disease is a common infection that usually presents as tender lymphadenopathy. it should be included in the differential diagnosis of fever of unknown origin and any lymphadenopathy syndrome. asymptomatic, bacteremic cats with bartonella henselae in their saliva serve as vectors by biting and clawing the skin. cat fleas are responsible for horizontal transmission of the disease from cat to cat, and on occasion, arthropod vectors (fleas or ticks) may transmit the disease to humans. ca ... | 2011 | 21243990 |
| unusual retinal manifestations of cat scratch disease. | we report on 2 patients with unusual retinal manifestations of cat scratch disease (csd), caused by bartonella henselae. case 1. a 42-year-old farmer presented with a 5-day history of blurred vision in his right eye. right visual acuity was 20/25. fundus examination of the right eye revealed mild vitreous hemorrhage and diffuse retinal hemorrhages in the mid-peripheral retina. fluorescein angiography showed multiple vasculitic occlusions in the same area. a blood sample taken on the day of exami ... | 2011 | 21267628 |
| fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type iv secretion system effector bepa. | numerous bacterial pathogens subvert cellular functions of eukaryotic host cells by the injection of effector proteins via dedicated secretion systems. the type iv secretion system (t4ss) effector protein bepa from bartonella henselae is composed of an n-terminal fic domain and a c-terminal bartonella intracellular delivery domain, the latter being responsible for t4ss-mediated translocation into host cells. a proteolysis resistant fragment (residues 10-302) that includes the fic domain shows au ... | 2011 | 21213248 |
| [vasoproliferative retinal tumours]. | vasoproliferative retinal tumors are benign tumors of unknown origin often accompanied by vitreoretinal inflammation. a 21-year-old female patient presented with acute reduced unilateral visual acuity. a solid yellow vascularized lesion was present in the inferior temporal retina accompanied by localized retinal detachment and accumulation of hard exudations. the only finding was an increased bartonella henselae titer. persistence of uveitis and blurred vision led to therapy for bartonella hense ... | 2011 | 21153829 |
| cat-scratch uveitis confirmed by histological, serological, and molecular diagnoses. | to report a case of a cat-scratch uveitis caused by bartonella henselae, which was confirmed by histology, serology, and polymerase chain reaction (pcr) methodology. | 2011 | 21099401 |
| challenges in the clinical management of blood-culture negative endocarditis: case of bartonella henselae infection. | 2011 | 21396492 | |
| three cases of pr3-anca positive subacute endocarditis caused by attenuated bacteria (propionibacterium, gemella, and bartonella) complicated with kidney injury. | subacute bacterial endocarditis (sbe) associated with antiproteinase-3 antineutrophil cytoplasmic antibodies (pr3-anca) has previously been reported in 10 cases of streptococcus viridans and in 1 case of escherichia faecalis infection. most of these patients had hypocomplementemia and were positive for several autoantibodies. the infections in most of these patients showed good responses to antibiotic treatment. we report three patients with anca-positive sbe, which was induced by attenuated slo ... | 2011 | 21400245 |
| bartonella henselae endocarditis of percutaneously implanted pulmonary valve: a case report. | percutaneous pulmonary valve implantation (ppvi) has revolutionized the management of right ventricular outflow tract dysfunction after repaired congenital heart disease. the technology is considered to be safe, with a relatively low complication rate. infection is one of the described complications of ppvi, and to date five cases of culture-positive infective endocarditis of percutaneously implanted pulmonary valve have been reported worldwide. herein is reported the first ever case of culture- ... | 2011 | 21404904 |
| 18f-fluoro-2-deoxyglucose positron emission tomography-negative endocarditis lenta caused by bartonella henselae. | it has been suggested that 18f-fluorodeoxyglucose positron emission tomography (fdg-pet) might serve as a tool for the often difficult diagnosis of infective endocarditis. the case is described of a patient with a bartonella henselae endocarditis with a negative fdg-pet. this case report demonstrates that negative fdg-pet findings do not rule out the presence of endocarditis. | 2011 | 21404906 |
| eschar and neck lymphadenopathy caused by francisella tularensis after a tick bite: a case report. | 2011 | 21418587 | |
| high throughput, multiplexed pathogen detection authenticates plague waves in medieval venice, italy. | historical records suggest that multiple burial sites from the 14th-16th centuries in venice, italy, were used during the black death and subsequent plague epidemics. | 2011 | 21423736 |
| [louse-borne infections in humans]. | 2011 | 21450425 | |
| [sero-epidemiological investigation on rickettsia typhi, bartonella henselae and orientia tsutsugamushi in farmers from rural areas of tianjin, 2007 - 2009.] | objective: to study the sero-epidemiological status regarding rickettsia (r.) typhi, bartonella (b.) henselae and orientia (o.) tsutsugamushi in farmers from rural areas of tianjin. methods: field epidemiological surveys were performed in 8 districts (county) of tianjin city from 2007 to 2009. 886 farmers were randomly recruited and their serum samples collected to detect the specific antibodies of r. typhi, b. henselae and o. tsutsugamushi by micro-indirect immunoflorescence (ifa). results: the ... | 2011 | 21457660 |
| seasonality of cat-scratch disease, france, 1999-2009. | cat-scratch disease is seasonal in the united states and japan; but no data are available from europe. to assess the seasonality of the disease in france, we analyzed lymph node biopsy specimens collected during 1999-2009. most (87.5%) cases occurred during september-april and peaked in december. | 2011 | 21470466 |
| multilocus sequence typing of bartonella henselae in the united kingdom indicates that only a few, uncommon sequence types are associated with zoonotic disease. | bartonella henselae is one of the most common zoonotic agents acquired from companion animals (cats) in industrialized countries. nonetheless, although the prevalence of infections in cats is high, the number of human cases reported is relatively low. one hypothesis for this discrepancy is that b. henselae strains vary in their zoonotic potential. to test this hypothesis, we employed structured sampling to explore the population structure of b. henselae in the united kingdom and to determine the ... | 2011 | 21471345 |
| bartonella quintana in head louse nits. | the body louse is the principal vector of bartonella quintana, the causative organism of trench fever, but b. quintana dna has also been detected in adult head lice. because there are no characteristics that distinguish the body louse from the head louse, we decided to test head louse nits collected from a homeless man for the presence of b. quintana dna. all of the sampled nits tested positive by real-time pcr, and intergenic spacer region (its) gene sequences shared 100% similarity to the corr ... | 2011 | 21477003 |
| prevalence of rickettsia felis and the first identification of bartonella henselae fizz/cal-1 in cat fleas (siphonaptera: pulicidae) from taiwan. | cat fleas (ctenocephalides felis [bouché]) are the primary ectoparasites of dog and cat populations. in this study, we report the monthly population dynamics of rickettsia felis and bartonella spp. (two zoonotic pathogens that can cause human disease) in cat fleas collected from dogs and cats in taipei, taiwan, from december 2006 to december 2007. natural r. felis infection in individual cat fleas was assessed by polymerase chain reaction (pcr) using prf-, ompb-, and glta-specific primer pairs. ... | 2011 | 21485388 |
| infective endocarditis. | infective endocarditis (ie) is lethal if not aggressively treated with antibiotics alone or in combination with surgery. the epidemiology of this condition has substantially changed over the past four decades, especially in industrialized countries. once a disease that predominantly affected young adults with previously well-identified valve disease-mostly chronic rheumatic heart disease-ie now tends to affect older patients and new at-risk groups, including intravenous-drug users, patients with ... | 2011 | 21487430 |
| adhesion and host cell modulation: critical pathogenicity determinants of bartonella henselae. | abstract: bartonella henselae, the agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis, contains to date two groups of described pathogenicity factors: adhesins and type iv secretion systems. bartonella adhesin a (bada), the trw system and possibly filamentous hemagglutinin act as promiscous or specific adhesins, whereas the virulence locus (vir)b/vird4 type iv secretion system modulates a variety of host cell functions. bada mediates b ... | 2011 | 21489243 |
| identification of bartonella henselae in 2 cats with pyogranulomatous myocarditis and diaphragmatic myositis. | most cats infected with bartonella henselae remain outwardly healthy carriers for years; however, self-limiting fever, transient anemia, neurologic dysfunction, lymphadenopathy, reproductive disorders, aortic valvular endocarditis, and neutrophilic myocarditis have been described in experimentally or naturally infected cats. two cats in a north carolina shelter died with pyogranulomatous myocarditis and diaphragmatic myositis. bacteria were visualized in the lesions by warthin-starry silver impr ... | 2011 | 21490304 |
| in silico analysis of 16s ribosomal rna gene sequencing based methods for identification of medically important aerobic gram-negative bacteria. | the study is the first one that provides guidelines on the usefulness of full and 527-bp 16s rrna gene sequencing and microseq databases for identifying medically important aerobic gram-negative bacteria. overall, full and 527-bp 16s rrna gene sequencing can identify 26.1% and 32.6% of medically important aerobic gram-negative bacteria confidently to the species level, whereas the full-microseq and 500-microseq databases can identify 15.2% and 26.1% of medically important aerobic gram-negative b ... | 2011 | 21498652 |
| absence of zoonotic bartonella species in questing ticks: first detection of bartonella clarridgeiae and rickettsia felis in cat fleas in the netherlands. | abstract: | 2011 | 21501464 |
| seroprevalence of toxoplasma gondii and concurrent bartonella spp., feline immunodeficiency virus, feline leukemia virus, and dirofilaria immitis infections in egyptian cats. | abstract toxoplasma gondii and bartonella spp. are zoonotic pathogens of cats. feline immunodeficiency virus (fiv) and feline leukemia virus (felv) are related to human immunodeficiency virus and human leukemia virus, respectively, and these viruses are immunosuppressive. in the present study, the prevalence of antibodies to t. gondii , bartonella spp., fiv, as well as felv and dirofilaria immitis antigens was determined in sera from feral cats ( felis catus ) from cairo, egypt. using a modified ... | 2011 | 21506874 |
| bone pain and fever in an adolescent and his sibling. cat scratch disease (csd). | 2011 | 21513084 | |
| bartonella spp. in feral pigs, southeastern united states. | in conjunction with efforts to assess pathogen exposure in feral pigs from the southeastern united states, we amplified bartonella henselae, b. koehlerae, and b. vinsonii subsp. berkhoffii from blood samples. feral pigs may represent a zoonotic risk for hunters or butchers and pose a potential threat to domesticated livestock. | 2011 | 21529405 |
| trimeric autotransporter adhesin-dependent adherence of bartonella henselae, bartonella quintana and yersinia enterocolitica to matrix components and endothelial cells under static and dynamic flow conditions. | trimeric autotransporter adhesins (taas) are important virulence factors of gram-negative bacteria responsible for adherence to extracellular matrix (ecm) and host cells. here, we analyzed three different taas [bartonella adhesin a (bada) of bartonella henselae, variably expressed outer membrane proteins (vomps) of bartonella quintana, yersinia adhesin a (yada) of yersinia enterocolitica] for mediating bacterial adherence to ecm and endothelial cells. using static (cell culture vials) and dynami ... | 2011 | 21536788 |
| bartonella spp. dna in cardiac tissues from dogs in colorado and wyoming. | background: several bartonella species (spp.) have been identified in dogs diagnosed with infectious endocarditis (ie) or myocarditis. objective: to interrogate cardiac tissues of dogs with suspected ie for the presence of bartonella spp. dna of dogs in the rocky mountain states. animals: nine dogs with a clinical diagnosis of endocarditis from january 1990 to june 2008 were included. methods: in this retrospective study, medical records at the veterinary teaching hospital were searched. animals ... | 2011 | 21539606 |
| brief communication: co-detection of bartonella quintana and yersinia pestis in an 11th-15th burial site in bondy, france. | historical and anthropological data suggest that skeletons excavated from an 11th to 15th century mass grave in bondy, france, may be those of victims of the great plague. using high-throughput real-time pcr investigation of the dental pulp collected from 14 teeth from five such skeletons, we detected bartonella quintana dna in three individuals and yersinia pestis dna in two individuals. dna from five other deadly pathogens was not found. suicide pcr genotyping confirmed y. pestis dna belonging ... | 2011 | 21541920 |
| adhesins of bartonella spp. | adhesion to host cells represents the first step in the infection process and one of the decisive features in the pathogenicity of bartonella spp. b. henselae and b. quintana are considered to be the most important human pathogenic species, responsible for cat scratch disease, bacillary angiomatosis, trench fever and other diseases. the ability to cause vasculoproliferative disorders and intraerythrocytic bacteraemia are unique features of the genus bartonella. consequently, the interaction with ... | 2011 | 21557057 |
| bartonella quintana endocarditis of the tricuspid and mitral valves. | bartonella quintana is a gram-negative microorganism that can lead to culture-negative infective endocarditis (ie) in immunocompromised patients. here, we present an exceptionally rare case of a 70-year-old male with bartonella quintana-associated ie primarily limited to the tricuspid valve that spread to the mitral valve after tricuspid valve replacement. this was then complicated by infective spondylodiscitis of the thoracic vertebrae, ultimately resulting in death due to cardiac arrest. | 2011 | 21557164 |
| prosthetic valve endocarditis caused by bartonella quintana in a patient during immunosuppressive therapies for collagen vascular diseases. | bartonella quintana, known to cause various clinical symptoms, is increasingly recognized as one important cause of culture-negative endocarditis. we report a case of infectious endocarditis with b. quintana on the prosthetic valve, accompanied by proteinase 3-antineutrophil cytoplasmic antibody-positive collagen vascular disease-like symptoms 1 year earlier. | 2011 | 21558050 |
| prevalence of bartonella species, haemoplasmas and toxoplasma gondii in cats in scotland. | the objective of this study was to determine the prevalence rates for select infectious agents of cats presented to the royal (dick) school of veterinary studies at the university of edinburgh, scotland. whole blood, serum, and oral mucosal and nail bed swabs were collected. while ehrlichia species, anaplasma species or rickettsia felis dna were not amplified from any cat, 44.2% of the cats had evidence of infection or exposure to either a bartonella species (15.3% were seropositive and 5.8% pol ... | 2011 | 21570883 |
| thoracic vertebral osteomyelitis with paraspinous mass and intraspinal extension: an atypical presentation of cat-scratch disease. | children with cat-scratch disease (csd) commonly present with fever and tender lymphadenopathy. the disease is mild and manifestations of infection resolve spontaneously within several weeks. however, some children with csd have unusual features that present diagnostic challenges. children with atypical csd may present with prolonged fever, hepatosplenic disease or ocular disease. we performed an mri on a child who presented with persistent back pain. the mri demonstrated a paravertebral mass wi ... | 2011 | 21594549 |
| rickettsia, ehrlichia, anaplasma, and bartonella in ticks and fleas from dogs and cats in bangkok. | abstract flea and tick specimens (5-10 fleas or ticks) on dogs and cats from various sites in bangkok were tested by polymerase chain reaction and dna sequencing to detect dna of bacteria rickettsia (glta and 17 kda genes), anaplasmataceae (16s rrna gene), and bartonella (pap31 and its genes). we confirmed that rickettsia sp. related to rickettsia felis was detected in 66 of 98 (67.4%) flea specimens from dogs, whereas 8 bartonella henselae and 2 bartonella clarridgeiae were detected in 10 of 54 ... | 2011 | 21612535 |
| molecular and serological diagnosis of bartonella infection in 61 dogs from the united states. | background: molecular diagnosis of canine bartonellosis can be extremely challenging and often requires the use of an enrichment culture approach followed by pcr amplification of bacterial dna. hypotheses: (1) the use of enrichment culture with pcr will increase molecular detection of bacteremia and will expand the diversity of bartonella species detected. (2) serological testing for bartonella henselae and bartonella vinsonii subsp. berkhoffii does not correlate with documentation of bacteremia ... | 2011 | 21615498 |
| umbilicated erythematous papules in an immunocompromised patient. | 2011 | 21616459 | |
| bartonella species and their ectoparasites: selective host adaptation or strain selection between the vector and the mammalian host? | a wide range of blood-sucking arthropods have either been confirmed or are suspected as important vectors in bartonella transmission to mammals, including humans. overall, it appears that the diversity of bartonella species dna identified in ectoparasites is much broader than the species detected in their mammalian hosts, suggesting a mechanism of adaptation of bartonella species to their host-vector ecosystem. however, these mechanisms leading to the fitness between the vectors and their hosts ... | 2011 | 21616536 |
| arthropod-borne diseases associated with political and social disorder. | the living conditions and the crowded situations of the homeless, war refugees, or victims of a natural disaster provide ideal conditions for the spread of lice, fleas, ticks, flies and mites. the consequence of arthropod infestation in these situations is underestimated. along with louse-borne infections such as typhus, trench fever, and relapsing fever, the relationship between acinetobacter spp.-infected lice and bacteremia in the homeless is not clear. murine typhus, tungiasis, and myiasis a ... | 2011 | 20822446 |
| bartonella spp.: throwing light on uncommon human infections. | after 2 decades of bartonella research, knowledge on transmission and pathology of these bacteria is still limited. bartonella spp. have emerged to be important pathogens in human and veterinary medicine. for humans, b. henselae is considered to represent the most relevant zoonotic bartonella species and is responsible for cat scratch disease, bacillary angiomatosis, and other disorders. over the years, many bartonella species have been isolated from humans, cats, dogs, and other mammals, and in ... | 2011 | 20833105 |
| recombination within and between species of the alpha proteobacterium bartonella infecting rodents. | bartonella infections from wild mice and voles (apodemus flavicollis, mi. oeconomus, microtus arvalis and myodes glareolus) were sampled from a forest and old-field habitats of eastern poland; a complex network of bartonella isolates, referrable to b. taylorii, b. grahamii, b. birtlesii and b. doshiae, was identified by the sequencing of a glta fragment, comparable to previous studies of bartonella diversity in rodents. nested clade analysis showed that isolates could be assigned to zero- and on ... | 2011 | 20740281 |
| unknown fever and back pain caused by bartonella henselae in a veterinarian after a needle puncture: a case report and literature review. | abstract bartonella henselae, the etiologic agent of cat-scratch disease, rarely causes back pain and is considered to be transmitted through animal scratches and bites. here we report a cat-scratch disease case possibly with an unusual route of transmission. the patient was a 32-year-old man, and he was working as a veterinarian in a private veterinary clinic. he sought for clinical help because of unknown fever and persistent back pain for at least a month after an accidental needle puncture. ... | 2011 | 20569013 |
| rickettsia felis and bartonella clarridgeiae in fleas from new caledonia. | dog fleas collected in new caledonia harbored flea-borne pathogens rickettsia felis and bartonella clarridgeiae in 81% and 5%, respectively. | 2011 | 20569017 |
| neuralgic amyotrophy associated with bartonella henselae infection. | 2011 | 20710009 | |
| molecular detection of ehrlichia canis, anaplasma bovis, anaplasma platys, candidatus midichloria mitochondrii and babesia canis vogeli in ticks from israel. | : ticks are vectors of important pathogens of human and animals. therefore, their microbial carriage capacity is constantly being investigated. the aim of this study was to characterize the diversity of domestic animal pathogens in ticks collected from vegetation and the ground, from different parts of israel. non-engorged questing adult ticks were collected from 13 localities. a total of 1196 ticks in 131 pools-83 pools of rhipicephalus turanicus and 48 of rhipicephalus sanguineus (with two to ... | 2011 | 20636417 |
| [unilateral neuroretinitis revealing cat-scratch disease]. | we report a case of cat-scratch disease neuroretinitis. a 26-year-old man was referred for severe right visual loss. posterior segment examination showed a papilledema with macular edema. bartonella henselae immunoglobulin g testing was positive. four weeks of antibiotic therapy combining oral ciprofloxacin and doxycycline led to progressive resolution of the neuroretinitis and improvement in visual acuity. this report reminds that b. henselae infection can be the cause of neuroretinitis. its pr ... | 2011 | 20646795 |
| [bilateral inguinal lymphadenopathy and erythema nodosum: an uncommon presentation of cat scratch disease]. | cat scratch disease is usually revealed by a proximal lymphadenopathy related to the inoculation site. we report a 22-year-old female who presented with erythema nodosum and bilateral inguinal lymphadenopathy. serologic test and lymph node pcr detection for bartonella henselae were negative. nevertheless, the patient received doxycycline and clinical manifestations rapidly resolved. a follow-up detection of igm and igg against bartonella henselae performed 1 month later was positive. this case r ... | 2011 | 20646798 |
| identification of bartonella henselae in a horse from germany. | 2011 | 21388754 | |
| suspecting optic neuritis, diagnosing bartonella cat scratch disease. | bartonella cat scratch disease is classically a febrile illness, in conjunction with lymphadenopathy and cat exposure. | 2011 | 21220684 |