Publications

cyanogen condensations as a route to 3-amino-2-imino-1,3-benzothiazin-4-ones with cns depressant potential.	seven new 3-amino-2-imino-1,3-benzothiazin-4-ones, prepared from the condensation of cyanogen and 2-mercaptobenzhydrazides, were evaluated in a neuropharmacological mouse profile. cns depression was observed in several members of the class.	1975	1151723
relationship of brain morphine levels to analgesic activity in acutely treated mice and rats and in pellet implanted mice.	the relationship of brain morphine concentration, determined fluorometrically, to tail-flick activity was investigated after acute and chronic morphine treatment of mice and acute treatment of rats. brain morphine levels were quantitatively related to the analgesic effect on acute administration, with levels of 100 and 140 ng/g of tissue corresponding to the ed50 in mice and rats, respectively. over a 90-minute time course after acute s.c. injection, the analgesic effect of morphine in the tail- ...	1975	1151736
comparative antihypertensive effects and tissue distribution of beta adrenergic blocking drugs.	the precise mechanism of the antihypertensive action of beta adrenergic blocking drugs is not known. both peripheral and central sites of action have been proposed. the comparative antihypertensive actions and tissue distribution of propranolol, pindolol and sotalol were investigated in both normotensive sprague-dawley and spontaneously hypertensive rats. from recordings of concurrent changes in blood pressure and heart rate it was observed that oral or subcutaneous administrations of both propr ...	1975	1151751
effects of nerve growth factors from mouse salivary glands and snake venom on the sympathetic ganglia of neonatal and developing mice.	1. quantitative histological analysis has been made of the effects of nerve growth factor (ngf) from mouse submaxillary gland and from the venom of vipera russelli on superior cervical ganglia of neonatal mice. 2. the hypertrophic and hyperplastic effects reported by other workers have been confirmed. 3. the hypertrophic effect arises from an increase in the rate at which the sympathetic neurones attain their mature size. the size at maturity is never exceeded. 4. the hyperplastic effect arises ...	1975	1151776
the effect of calcium ions on the binomial statistic parameters which control acetylcholine release at synapses in striated muscle.	a study has been made of the effects of changing [ca]o and [mg]o on the binomial statistic parameters p and n which control the average quantal content (m) of the synaptic potential due to acetylcholine release. 2. when [ca]o was varied in the range 0-1 to 1-0 mm, p increased as the first power of [ca]o whereas n increased as the third power of [ca]o. 3. increasing [mg]o depressed both p and n, however variations of [ca]o in the presence of high [mg]o did not significantly change the power relat ...	1975	1151780
convergence in a thermal afferent pathway in the rat.	1. in anaesthetized rats, unit activity was recorded in the afferent somatosensory pathway leading from the scrotum. recording sites were in the dorsal horn near the entry zone of the scrotal nerve, in the ventrobasal complex of the thalamus and in the somatosensory (si) cortex. during recording, the temperatures of the left and right sides of the scrotum were varied independently. 2. almost all (64/67) the units in dorsal horn, thalamus and cortex responding specifically to scrotal temperature ...	1975	1151788
proceedings: effects of histamine, 2-methylhistamine and 4-methylhistamine on blood pressure and vascular resistance in the cat.		1975	1151865
human monocyte metabolism: male vs. female.		1975	1151943
femoral percutaneous catheterization in infants and small children for cerebral angiography.	an improved technique of selective cerebral angiography for infants and small chicken is described. the needle is inserted approximately 45 degrees to the skin in order to avoid subintimal placement of the tip. after good backflow is established, the guidewire is advanced to a position in the descending aorta. a no. 3 polyethylene catheter and 21-gauge scalp vein needle were most successful.	1975	1153751
further evidence for cross-linking as a protective factor in experimental cholera: properties of antibody fragments.	enzymic fragments of igg antibody were tested for their protective abilities in the infant mouse cholera model. f(ab')2 retained the full protective activity of the parent igg molecule despite losses in complement fixation and opsonic functions. fab' and fab fragments also contained significant protective activity but at a level of only 10% of the intact igg or f(ab')2. self-recombinant univalent f(ab')2 also contained about 10% of the protective activity of the divalent f(ab')2 parent molecule. ...	1975	1159322
antibody cross-linking as a factor in immunity to cholera in infant mice.	several antibody preparations were tested for their ability to reduce adsorption of vibrio cholerae to isolated intestinal epithelial cells, and this ability was related to agglutination and protective activity in infant mice. the results demonstrate that (1) the reduction in adsorption of v. cholerae to epithelial cells correlates with the degree of agglutination for given antibody preparation; (2) intact tantibodies protect infant mice from cholera only at concentrations that agglutinate the b ...	1975	1159323
proceedings: observations on the cholera enterotoxin (choleragen).		1975	1160198
[effect of infant foods enrichment with iron salts on hemoglobin and hematocrit values and serum iron levels in young infants].		1975	1160233
dietary fats and properties of endoplasmic reticulum: i. dietary lipid induced changes in composition of microsomal membranes in liver and gastroduodenal mucosa of rat.	rats were fed for four weeks with different lipid diets to determine the effects on the endoplasmic reticulum membranes of the liver and on the postmitochondrial supernatant fraction of the gastroduodenal mucosa. the diets contained cholesterol, cacao butter, olive oil, and these in combination. the results showed that dietary lipids were able to modify the composition of the hepatic endoplasmic reticulum and, to a lesser extent, that of postmitochondrial fraction of gastroduodenal mucosa. cacao ...	1975	1160521
interrelationship between configurational state and metabolism in mitochondria.		1975	1163126
socio-economic and environmental factors and human health example of cholera el tor in manila.	the environmental health factors relevant to the occurrence of cholera in an urban milieu (manila) have been studied. cholera has been found to be a disease significantly more prevalent in the areas with lowest environmental condition. association have been found between the disease incidence and several socioeconomic variables: population density, water and sewer connections each per 1000 population and squatter/slum dweller density. the correlation between cholera incidence and population dens ...	1975	1163167
antibacterial mechanisms in the intestine. elimination of v. cholerae from the gastrointestinal tract of adult mice.		1975	1164261
antibacterial mechanisms in the intestine. elimination of v. cholerae from the intestines of infant mice and the role of antibody.		1975	1164262
binding of cholera toxin by various tissues.	under certain conditions, it is possible to confirm the observation by peterson (1974) that the cholera toxin-binding capacities of tissues from brain and colon mucosa, and from liver and small intestine mucosa, are comparable. binding of toxin by all tissues except brain is very variable, but is roughtly proportional to their content of the toxin-binding ganglioside galactosyl-n-acetylgalactosaminyl (sialosyl) lactosyl ceramide. it appears that some toxin-binding sites of the mucosa of the smal ...	1975	1165119
comparative morphology of genital cones of genus ancylostoma dubini, 1843.	male worms of ancylostoma braziliense, a. ceylanicum, a. kusimaense, a. malayanum, a. duodenale, a. caninum, a. tubaeforme, agriostomum vryburgi and cyclodontostomum purvisi have the external appendages beside the anogenital aperture. these anogenital structures are morphologically similar and are assumed to be homologous among the species with three pairs of teeth or more. in hookworms with two pairs of teeth, the anogenital structures are complex. anogenital features can be used as a taxonomic ...	1975	1166351
specific effect of neuraminidase on blastogenic response of sensitized lymphocytes.	the blastogenic response of sensitized lymphocytes from guinea-pigs to 'de novo' antigens (klh, hch and ppd) was ehhanced by bcn treatment in twenty-one of twenty-three instances. in contrast, no effect of vcn on nonsensitized guinea-pig lymphocyte response to these antigens, or to mumps antigen, was noted in any of thirty-four instances, these findings indicate that the enhancement effect of vcn is specific for sensitized lymphocytes. heating vcn at 100 degrees for 10 minutes completely abolish ...	1975	1168168
in vitro depression of cellular immunity by friend virus leukemic spleen cells.		1975	1168547
preparation of high-quality iodine-125-labelled pituitary luteinizing hormone for radioimmunoassay.	high quality pituitary luteinizing hormone labelled with 125-i was obtained after separating out the more heavily iodinated fractions, through starch gel electrophoresis, using the cathodal component (fraction 1) which was further purified on sephadex g-100, giving an almost pure 125-i-labelled luteinizing hormone preparation, presenting excellent immunoreactivity and low levels of damage on incubation in plasma. the quality control of the steps of the technique was done with plasma-coated talc ...	1975	1168555
combined staining of protein-bound sulphydryl groups and dna in polyacrylamide model systems.	a model system of polyacrylamide films containing protein and dna has been used to examine the feasibility of combining the dihydroxydinaphthyldisulphide (ddd)-diazonium salt procedure for localizing protein-bound sulphydryl groups with the feulgen technique for dna to make possible the direct measurement of both these parameters simultaneously. optimun conditions for the sulphydryl group reaction require reduction of the protein-containing films in 10% aqueous ammonium sulphide for 3 hr at 50 d ...	1975	1168630
transport and storage of serotonin by thrombin-treated platelets.	repeated thrombin treatment of washed platelets prepared from rabbits can decrease the serotonin content of the platelets by about 80%. when these platelets are deaggregated they reaccumulate serotonin but their storage capacity for serotonin is reduced by about 60%. if thrombin-pretreated platelets are allowed to equilibrate with a high concentration of serotonin (123 mu m), they release a smaller percentage of their total serotonin upon further thrombin treatment, in comparison with the percen ...	1975	1168649
motility of the oviduct and uterus of the cow during the oestrous cycle.	recordings of electrical activity of the oviduct and uterus were obtained during three oestrous cycles in cows fitted with an extra-cellular multi-electrode assembly. the stages of the cycle were identified by the appearance of the cervico-vaginal secretions and changes in the peripheral plasma level of progesterone were determined by radioimmunoassay. a gradual transition from local non-propagating electrical activity to propagating electrical activity with increase in the duration of contracti ...	1975	1168710
hl-a w27 in psoriatic arthropathy.	forty subjects with psoriatic arthritis (pa) underwent hl-a tissue typing. hl-a w27 was significantly increased in psoriatic spondylitis (35%), whereas statistical significance was not reached in patients with peripheral arthritis alone, although w27 was present in a frequency greater than in controls. psoriatic spondylitis (often asymptomatic) occurred in 57% (23 of 40) of our pa patients. of interest, psoriatic spondylitis was more often w27 negative than w27 positive; nevertheless, w27-positi ...	1975	1169069
on the role of sialic acid in the rheological properties of mucus.	the importance of sialic acid in the rheological properties of mucus has been investigated. both bovine cervical mucus, which is a gel, and the structural glycoprotein derived from it were studied before and after treatment with neuraminidase which selectively cleaves terminal sialic acid residues. the storage modulus, viscosity and circular dichroism spectrum were all essentially changed after removal of the sialic acid. these results would indicate that removal of sialic acid does not affect t ...	1975	1169073
[the effect of neuraminidase on the corpus luteum of the pregnant mouse. an ultrastructural study].		1975	1170110
cell contact-dependent ganglioside changes in mouse 3t3 gibroblasts and a suppressed sialidase activity on cell contact.	certain enzyme activities for synthesis and degradation of gangliosides and the chemical quantity and incorporation of radioactivity from [14c] galactose into gangliosides have been studied in 3t3 cells and their transformed counterparts at various cell population densities. the chemical quantity of and the incorporation of radioactivity into gd1a ganglioside increased at the early stage of cell contact ("contact response" of ganglisoide), whereas response was not detectable in transformed 3t3 c ...	1975	1170879
relation of the neuraminidase-revealed antigens of human lymphocytes and erythrocytes.		1975	1171544
interaction of furazolidone with dna.	dn forms a complex with furazolidone producing thereby a quenching and a bathochromic shift of the drug absorption pattern. the binding isotherm was a non-linear one indicating involvement of more than one binding process in the formation of the furazolidone - dna complex. the furazolidone - dna complex inhibited digestion of dna by dnaase and stabilized dna against thermal strand separation by a significant degree.	1975	1174533
metabolic actions of vasopressin, glucagon and adrenalin in the intact rat.	metabolic effects of vasopressin, glucagan and adrenalin were compared, in intact rats, especially in regard to time courses of effects. hyperglycaemia was transient in response to vasopressin, prolonged following adrenalin, and, suprisingly, was not discernible after glucagon, except in response to a very large dose. vasopressin decreased and adrenalin increased, the plasma free fatty acid concentration; both hormones decreased the triacylglycerol level. muscle glycogen concentrations, measured ...	1975	1182200
cholera toxin effects on cell growth accompanied by selective alterations in metabolite uptake and modification of cell surface proteins.	exposure of chinese hamster ovary cells to cholera toxin at or below mug levels causes a marked morphological changes and increased adhesion and orientation of the cells. such changes are paralleled by alterations in surface proteins as indicated by the cholera toxin-mediated modifications detectable by lactoperoxidase-catalyzed radioiodination of outer proteins. mild tryptic treatment of cells prelabeled with [3h]glucosamine revealed a different kinetics of release of external glycoproteins in ...	1975	1182696
the organized distribution of acrosomal proteinase within the acrosomes of rabbit spermatozoa.	acrosomal proteinase was found to be present in a highly organized distribution in the acrosomes of rabbit spermatozoa, using cytochemistry. this distribution consists of at least six linear loops of evenly spaced proteinase granules, which run diagonally across the flat side of the sperm head in a criss-crossing pattern. two additional loops may be present, one encircling the tip of the spermatozoon in the region of the acrosome reaction, and the other at the posterior end of the acrosome. the ...	1975	1183631
viability of vibrio cholerae biotype el tor and of cholera phage on vegetables.	different vegetables were contaminated with sewage water containing large amounts of el tor vibrios, and the viability of these vibrios was studied under defined conditions of storage. during the dry season (summer) in jerusalem, the el tor vibrios survived for up to 24 hr on parsley, 24 to 30 hr on tomatoes and carrots, 24 to 48 hr on cucumbers, peppers and okra and two to three days on lettuce, when the vegetables were stored at room temperature. the survival time was longer during the rainy s ...	1975	1184361
metabolism of [5-t]fructose by isolated liver cells.	glucose formed from [5-t]fructose in rat hepatocytes contains about 10 to 30% tritium. this does not appear to be due to fructose metabolism via hexokinase since neither the initial presence of glucose, nor wide variations in the original fructose concentration, have much effect on the relative labeling of glucose versus water from [5-t]fructose. comparison of the t:14c ratios in glucose produced from [u-14c, 5-t]fructose and d-[u-14c, 2-t]glyceraldehyde indicate that there is tritium retention ...	1975	1184583
effects of cholera toxin on adenylate cyclase. studies with guanylylimidodiphosphate.	similarities exist between the properties of adenylate cyclase after stimulation by cholera toxin and after stimulation by guanylylimidodiphosphate (gpp-(nh)p). thus a strong stimulation is achieved by both agents, the stimulation is essentially irreversible, the action of certain hormones is enhanced and the enzyme can be solublized with lubrol px in the activated state. because of these similarities the interaction of cholera toxin and gpp(nh)p on adenylate cyclase was examined. it was found t ...	1975	1184756
microbiological examination of ship sewage for the presence of vibrio cholerae.		1975	1191809
pharmacodynamic action of antygen vi.		1975	1191811
selective inhibition of cholera toxin- and catecholamine-stimulated lipolysis by blocking agents.	vibrio cholerae enterotoxin stimulates lipolysis in rat epididymal fat cell suspensions. like hormones this toxin increases adenylate cyclase activity, raising levels of cyclic adenosine 3',5'-monophosphate (camp), which activates a cellular lipase. using specific blocking agents, we studied the responses to the adrenergic lipolytic hormones epinephrine, norepinephrine, and isoproterenol, and to cholera toxin. all stimulators were used at 100 x threshold dose. propranolol (34 mum), a beta blocki ...	1975	1193734
laryngeal structure following microcauterization.	the paper supports and reaffirms the objectives of contemporary laryngology in the treatment of cancer of this organ. these objectives are, first and foremost, the eradication of the tumor, and second, the preservation of function. a relatively recent contribution to the "state of the art" has been the development of the field of microlaryngology. the introduction of the surgical microscope has provided the laryngologist with better means to judge the type, localization and extent of neoplastic ...	1975	1195967
comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques.		1975	1196002
synchronization of the fission yeast schizosaccharomyces pombe using heat shocks.		1975	1196141
pharmacological investigations on elaeocarpus ganitrus.		1975	1197422
immunotherapy with neuraminidase-treated tumor cells after radiotherapy.		1975	1197655
[influence of qualitatively different diets on the reproductive capacity and function of the adrenal cortex in rats with experimental toxic hepatitis].	the effect of a diet rich in protein and the group b vitamins on the function of the ovaries and adrenal cortex, as well as on the reproductive capacity of animals with experimental affection of the liver produced by administration of carbon tetrachloride was studied on 115 mongrel albino female-rats. a high-standard semisynthetic diet devised at the institute of nutrition of the ams of the ussr and three isocaloric experimental diets calorifically enriched by 20, 50 and 100 per cent and contain ...	1975	1199012
[changes in the lungs of white mice under the action of cholera exotoxin].		1975	1199577
isolation of single cell nuclei from human epidermis for cytophotometric dna--measurements.	diluted acetic acid was applied to dissociate human epidermis into its constituents. a simple procedure to gain isolated single cells for cytophometric determination of their nuclear dna content is described. the method is suited for single cell cytophotometric measurements and for cytofluorimetric flow systems likewise. the losses of feulgen--stainable nuclear dna during preparation were studied in dependence on the incubation time of the cells in acetic acid. the kinetics of extraction of nucl ...	1975	1200706
location and the primary structure around the disulfide bonds in cholera toxin.		1975	1201095
dermo--epidermal adhesion and its effect on epidermal structure in the mouse.	evidence is presented that dermo--epidermal adhesion is low in mouse ear. consequently the pressure caused by mitotic activity in the basal epidermal layer is readily relieved by cell extrusion distally and the number of basal cells per unit skin area remains low. the rule then is that the number of distal cells per unit skin area must be equally low, and the epidermis is therefore thin. conversely, dermo--epidermal adhesion is high in mouse sole-of-foot epidermis, and the mitotic pressure leads ...	1975	1201191
an improved method of assessing topical corticosteroid activity.	topical application of ointment bases causes varying degrees of epidermal thickening in guinea-pigs. this is reproducible and can be accurately measured. suppression of these changes was produced by addition of beta-methasone 17-valerate, fluocinolone acetonide, fluocinonide and hydrocortisone acetate. the inhibitory effect of these steroids was related to the type of corticosteriod, its concentration and the ointment base. the effect was still evident at extremely high dilutions of the steroids ...	1975	1201192
pure red cell aplasia: studies on an igg serum inhibitor neutralizing erythropoietin.	a new type of igg serum inhibitor in adult pure red cell aplasia (prca) has been investigated. this inhibitor is directed against circulating erythropoietin (ep) (prca type b), rather than the erythroid marrow (prca type a). thus, the igg inhibitor, after interaction with ep in solution, is precipitated together with ep by addition of goat anti-human gamma-globulins. pre-therapy prca serum, although apparently devoid of ep, shows considerable ep activity following acidification and boiling. the ...	1975	1201224
binding of vitamin b12--rat transcobalamin ii and free vitamin b12 to plasma membranes isolated from rat liver.	when dialysed rat serum which contains a single, low molecular weight binder for vitamin b12, rat transcobalamin ii (rat tc-ii), was labelled in vitro with 57co-vitamin b12 and then incubated at 30 degrees c (ph 7-5) with vesicles of highly purified plasma membranes separated from microsomal fractions of rat liver by density gradient centrifugation, the 57co-vitamin b12-rat tc-ii complex bound to high affinity sites on the vesicles via a specific (binding after correction for 'non-specific' bind ...	1975	1201244
ultrastructural studies of the bone marrow in sickle cell anaemia. ii. the morphology of erythropoietic cells and their response to deoxygenation in vitro.	electron microscopic studies of bone marrow aspirates obtained from patients with homozygous sickle cell anaemia (hbss) were fixed immediately without attempts to deoxygenate the samples. erythroblasts and normoblasts in these preparations were devoid of haemoglobin polymers or other indications of sickling. furthermore, the nucleated erythroid cells from sickle-cell patients presented an ultrastructural morphology indistinguishable from that of identically-processed erythroid cells in marrow sa ...	1975	1201249
comparative study of the smooth muscle contractor activity of airborne dusts and of dustiness in cotton, flax, and jute mills.	a bioassay technique using isolated guinea-pig ileum was employed to compare the smooth muscle contractor activity of various dusts from mills in which the prevalence of byssinosis was known. the activity of dust from a mill spinning a coarse grade of cotton was several times greater than that in dust from a mill processing a fine grade of cotton. there was a similar order in the difference of the prevalence of byssinosis in these mills. however, the activities of fine cotton, flax, and jute dus ...	1975	1201255
immunoglobulin synthesis and antibody content in the small intestine of the rabbit.	the concentration of immunoglobulin and specific antibody in the serum and the intestinal fluid and the rate of synthesis of immunoglobulin in the small intestine was measured in normal and immunized rabbits. iga was found to be the predominant immunoglobulin in the intestinal fluid. iga and igg were secreted at rates of 4-3 mug/cm/hr and 1-3 mug/cm/hr respectively. specific anti-vibrio cholerae antibodies in the intestine were found mainly in the iga class after oral immunization.	1975	1204251
pinocytic activity in neuraminidase treated ameba.		1975	1205516
comparison of the rate of absorption and proteolysis of [14c]choleragen and [14c]bovine serum albumin in the rat jejunum.	[14c]choleragen was used to study the rate of disappearance of choleragen enterotoxin from the jejunum of rats. [14c]bovine serum albumin (bsa) was studied in a similar manner. almost one-third of the labeled toxin had disappeared from the intestine after 6 h. its rate of disappearance was the same in germfree rats as in conventional rats. the rate of proteolysis of [14c]choleragen and [14c]bsa by intestinal mucodal lysosomal enzymes was also studied. neither was significantly degraded by neutra ...	1975	1205622
rapid and reliable preparation of macroaggregated albumin suitable for lung scintigraphy.		1975	1205665
protein reagent modification of cholera toxin: characterization of effects on antigenic, receptor-binding and toxic properties.	the effects of protein modification procedures on the biologically most important properties of cholera toxin, i.e. the toxic activity, the gm1 receptor-binding capacity and the antigenic (antibody-fixing) properties, have been studied quantitatively using microgram amounts or less of toxin protein. most of the 24 group-specific reagents used had either no inhibitory effect on the toxic or the combination of gm1-binding and antibody-fixing properties of cholera toxin, or they had a concomitant i ...	1975	1206372
growth inhibition of vibrio cholerae by d-camphor.		1975	1206376
abortifacient effects of vibrio cholerae exo-enterotoxin and endotoxin in mice.	to study antifertility properties of microbial toxins, exoenterotoxin and endotoxin from vibrio cholerae were injected intravenously into mice at different times during pregnancy. the two substances induced termination of pregnancy, but the patterns of abortifacient activity were different. exotoxin terminated pregnancy in mice when administered between days 4 and 10 of gestation, but abortifacient activity was reduced in animals more than 10 days pregnant; exogenous progesterone did not protect ...	1975	1206628
[utilization of serological methods in the retrospective diagnosis of cholera and in detecting vibrion carriers].	sensitivity and specificity of the three serological methods were studied comparatively: the vibriocidal test, the reaction of bacterial agglutination and of indirect hemagglutination, with the use of erythrocytes sensitized with the vibrio lyzate, cholera species o-antigen and cholerogen. investigations were conducted with the blood sera of cholera patients, vibrio carriers and contacts. vibriocidal test proved to be the most sensitive; its data correlated with the results of bacterial agglutin ...	1975	1210898
[role of neuraminidase from cholera vibrions in the pathogenesis of experimental cholera].	a study was made of a possible effect of neuraminidase of cholera vibrios on cholera pathogenesis. it was shown that in intraintestinal injection of cholera vibrios of the el tor biotype to nursling rabbits neuraminidase could be revealed in their intestine 5 to 8 hours after the infection. addition of neuraminidase to the weakly cholerogenic strain cholera vibrios intensified its cholerogenic action in infection of the animals. the antineuraminidase serum administered to the infected rabbits pr ...	1975	1210912
a salmonella california contamination of a turkey feed concentrate.		1975	1212606
selective chemical changes of gonadotropic hormones by means of neuraminidase from vibrio cholerae.	experiments indicate that neuraminidase from vibrio cholerae selectively cleaves sialic acid derivate from fsh, but leaves the lh sialic acid derivative. by performing a specific test for lh - the oaad test - we found that the lh activity is not influenced by the presence of neuraminidase. the fsh activity is destroyed by neuraminidase but the enzyme itself influences the ovarian weight, resulting in a weight decrease observed 48 hours after injection. before or after this "critical time" no dec ...	1975	1212991
[comparative study of the epidemiology of cholera and sensitivity to antibiotics of strains collected during the epidemiological period in 1971 and 1972 in wilaya de constantine].		1975	1213515
studies on the so-called nag vibrios.		1975	1213771
studies on bacteriology of cholera infection in varanasi.		1975	1213804
[changes in the composition of intracellular lipids and hydrocarbons in candida tropicalis in the absence of growth].	the fatty acid composition of lipids and the composition of hydrocarbons were studied in candida tropicalis cultivated on a medium with propionic acid and incubated in the conditions of starvation and on a medium containing glucose-1-6-14c but no nitrogen. intracellular fatty acids with an odd number of carbon atoms were found to be easily metabolized by yeast cells. the content and composition of intracellular hydrocarbons were very labile and underwent intensive transformation caused by change ...	1975	1214607
[antimicrobic properties of facultative anaerobes isolated from oil-bearing wells].		1975	1214635
[formation of fatty acids by aspergillus ochraceus 15b growing on a hexadecane containing medium].		1975	1214637
[electron microscopic study of double infection induced by potato virus x and potato virus y in nicotiana glutinosa].		1975	1214639
[salmonellosis carrier state].		1975	1214656
[electron microscopy of cholera vibrios from the intestinal contents of infected suckling rabbits].	electron microscopic study of the cells of classic, el tor and nag-vibrios showed them to be no different by the structure type from the cells of ofter gram-negative bacteria. a characteristic peculiarity of the cholera vibrios revealed after their passage through the intestine of nursling rabbits was the presence of microcapsules and protrusions of the areas of the wall membranous apparatus.	1975	1217357
recent studies on genetic recombination in vibrio cholerae.		1975	1219899
interbiotype conversion of cholera vibrios by action of mutagens.		1975	1219900
the antibody basis of local immunity to experimental cholera infection in the rabbit ileal loop.		1975	1219901
bacteriology at the periphery of the cholera pandemic.		1975	1219904
virulence-enhancing effect of ferric ammonium citrate on vibrio cholerae.		1975	1219909
cell-wall antigens of v. cholerae and their implication in cholera immunity.		1975	1219915
[ecg characteristics during its recording from electroanomalous points of the skin].		1975	1223350
the effects of cholera enterotoxin on intestinal tissue water as measured by nuclear magnetic resonance (nmr) spectroscopy.	cholera enterotoxin has been postulated to change the configuration of the intracellular protein-water system, altering the permeability of the cell to water. using nuclear magnetic resonance (nmr) spectroscopy, this protein-water relationship can be examined. small intestinal loops in the rat were injected with 0.5 ml of either schwarz/mann cholera enterotoxin (40 mug/cc saline solution) or normal saline. full thickness segments of intestine from each loop were taken and percentage water (using ...	1975	1223921
the anomeric configuration of n-acetylneuraminic acid released by the action of vibrio cholerae neuraminidase.		1975	1227974
the in vitro activity of midecamycin against various vibrio species.	the susceptibility of various vibrio species to midecamycin was studied by the tube dilution method. a mic of 100 mug per ml of midecamycin in bhi broth was taken as an indicator of bacterial resistance. all vibrio cholerae classic biotype strains tested, were sensitive to midecamycin. in respectively, 87.4%, 60.7% and 89.5% of vibrio cholerae el tor biotype, vibrio parahaemolyticus and vibrio nag strains tested, were sensitive to midecamycin.	1975	1228226
[serological response in man to an anticholera vaccine made from killed vibrios and partially purified with aluminium hydroxide].	the immunizing capability of a new anticholera vaccine (choleric anatoxin + vibrios ogawa and inaba) was tested on a group of 113 subjects. the vaccination was carried out with two inoculations of the vaccine, administered a month apart. testings were taken before the vaccination, before the second inoculation and 10 to 14 days after the vaccination was completed. the determination of the vibriocide antibodies was made following the test-tube method described by verwey and al., and the research ...	1975	1230039
[studies on the bacteriological diagnosis of cholera and on the characteristics of isolated strains in the apulia epidemic during the summer of 1973].	descriptions are given of the characteristics of 107 strains of vibrio cholerae of the serum type ogawa isolated during the epidemic in 1973, which, although not exhibiting hemolysis in liquid culture, could be assigned because of their other characteristics to the el tor biotype and to the phagic type 1. the authors also make a number of technical annotations on the bacteriological diagnosis of cholera.	1975	1230046
[preliminary studies on anti-brucella agglutinins and on immunoglobulins in subjects affected by cholera during the 1973 epidemic in the province of bari].	the behaviour of brucella agglutinins in sera from 70 cholera patients has been investigated. agglutinins for brucella, at titers of 1/40 or higher, occurred in 45 patients (64,2%); it has also been showed an antibody rise in 41 subjects with a peak titer during the second week, just like cholera agglutinins. this fact confirms the antigenic interrelationship between vibrio cholerae and brucella group. the serum immunoglobulins, during the course of infection, have been determined. mean levels o ...	1975	1230047
[studies on the spread of vibrio cholerae, biotype el tor in the environment during the period following the 1973 epidemic in apulia].	in the period following the cholera epidemic, studies were made of sewage, seawater and various foodstuffs (green vegetables, mussels, etc.) in an attempt to isolate vibrio cholerae of the el tor biotype. only in the samples of sewage taken at bari and taranto was it possible to isolate vibrio cholerae biotype el tor for a period of about a month after the last case of the illness; in this period it was isolated in 5 of the 11 samples taken at bari and in 1 of the 14 taken at taranto. the positi ...	1975	1230048
genetic influence on saline consumption and salt hypertension as exhibited by the response of various rat strains and sub-strains.	female rats of 2 sprague-dawley sub-strains and of the wistar and fischer 344 strains were sensitized to the hypertensogenic effect of excess salt by removal of 1 kidney and by being given 1% nacl solution as their sole drinking fluid. one of the sprague-dawley sub-strains (spd) and the wistar (cfep) rats developed progressive saline polydipsia of equivalent degree, blood pressure rose, and about half of the members became hypertensive during treatment. rats of the other sprague-dawley strain (c ...	1975	1231046
[zoonoses in veterinary practice. 3. chlamydial, rickettsial and fungal infections].		1975	1231047
[induction of interphase chromosome condensation in cultured human lymphocytes].		1975	1231100
[a cytophotometric and karyometric study of the granular cells of the rat brain. i. granular cells of the cochlear complex and cerebellum].	two cell types can be distinguished in granular cells of the chochlear complex of the rat by the form of their processes and the structure of the nuclear chromatin. it is shown cytophotometrically that the majority of the granular cells of the cochlear complex and in the cerebellar cortex are diploid. however, some cells contain dna amount close to tetraploid. some correlation between the size of the nucleus and its dna amount was discovered both in the cerebellar cortex and in the cochlear comp ...	1975	1231101
[characteristics of various nag vibriones isolated in italy].	in this paper are reported the results of a comparative study of 4 "nag" vibrio strains isolated in italy and the vibrio biotype "e1 tor" responsible of the 1973 outbreak. the "nag" vibrios were practically identical with the "e1 tor" vibrio in biochemical properties, polypeptide composition, enteritogenic activity in rabbit ileal loops and showed various antigenic similarities in gel precipitation and indirect immunofluorescence tests. the possible pathogenic role of the "nag" vibrios is briefl ...	1975	1231657
[effect of different types of rations on various characteristics of ruminal and intermediary metabolism in sheep. 1. formation of volatile fatty acids].	studies on ruminal physiology were made with 15 growing female merino sheep to investigate the influence of different types of rations on the fermentation of volatile fatty acids. the rations were constructed of green feed, straw and concentrates (type 1) or chemically treated straw pellets + concentrates (type 2). one ration (type 3) consisted of concentrates only. with regard to the total concentration of acids ration 3 was significantly superior to the 2 other types of rations. moreover, rati ...	1975	1233967
stimulation and inhibition of dna synthesis in rat thymocytes: action of concanavalin a and wheat germ agglutinin.		1975	1234047
hbs-ag, hbc-ag and virus-like particles in liver tissue.	hepatitis b surface antigen (hbs-ag) and hepatitis b core antigen (hbc-ag) in hepatic tissue of 3 cases with various liver diseases were investigated by immunofluorescent method. virus-like particles were demonstrated by electron microscopy in the nuclei of these 3 cases. the localization of hbs-ag was restricted in cytoplasma or on the surface of hepatocyte, while hbc-ag was almost in the hepatocytic nuclei. however, there was unexplainable discrepancy between the distribution of hbs-ag and tha ...	1975	1234098
numerical analysis and computerized identification of the yeast genera candida and torulopsis.	numerical analysis of the published standard descriptions of 104 species of candida and 48 species of torulopsis suggested that the number of species should be reduced to 78 and 33 respectively. four examples are noted of closely matched species differing in ability to assimilate nitrate; these species may be combined as nitrate-variable species. although the ability to form pseudomycelium is the only important difference between the genera, only three examples were noted of candida and torulops ...	1975	1236931
cellular kinetics of the intestinal immune response to cholera toxoid in rats.	the aims of this study were (a) to find a regime of immunization with cholera toxoid in rats which would establish a high density of antitoxin containing cells (acc) in the lamina propria of the intestine and (b) to determine the origin of the acc. the best cellular response was achieved by a single i.p. dose of toxoid in fca followed by an intraintestinal boost 2 wk later. acc appeared in the thoracic duct lymph 2 days after boosting, reaching a peak of about 200,000 acc/h at 3--4 days. this wa ...	1975	1238506