Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| effect of a chronic nail-biting habit on the oral carriage of enterobacteriaceae. | nail biting is a common oral habit in children and young adults. however, its effect on the oral carriage of enterobacteriaceae is unclear. the purpose of the study was to evaluate the differences in prevalence of enterobacteriaceae in saliva samples from subjects with and without a nail-biting habit. | 2007 | 17241163 |
| predictors of in-hospital mortality for bloodstream infections caused by enterobacter species or citrobacter freundii. | to identify predictors of in-hospital mortality among patients with bacteremia caused by enterobacter cloacae, enterobacter aerogenes, or citrobacter freundii. | 2007 | 17253909 |
| emerging bacterial pathogens: escherichia coli, enterobacter aerogenes and proteus mirabilis clinical isolates harbouring the same transferable plasmid coding for metallo-beta-lactamase vim-1 in greece. | 2007 | 17255145 | |
| synthesis of pseudopeptides based l-tryptophan as a potential antimicrobial agent. | four compounds named l-btrppa, l-trp-o-pa, l-trp-m-pa and l-trp-p-pa, pseudopeptides constructed from pyridine and tryptophan units, were synthesized and tested against the gram-positive, gram-negative strains of bacteria and human pathogenic fungi. l-trp-o-pa proved to be a broad-spectrum antimicrobial agent, showing a significant inhibition of the growth of gram-positive bacteria (staphylococcus aureus, methicillin-resistant s. aureus, bacillus subtilis, micrococcus luteus), and pathogenic fun ... | 2007 | 17257839 |
| management of risk of microbial cross-contamination from uncooked frozen hamburgers by alcohol-based hand sanitizer. | this research was undertaken to determine the effectiveness of an alcohol-based hand sanitizer on hands contaminated with a nonpathogen surrogate for escherichia coli o157:h7, where the source of the contamination was frozen hamburger patties. a nonpathogenic nalidixic acid-resistant food-grade strain of enterobacter aerogenes was used to inoculate frozen hamburger patties composed of 76% lean beef and 24% fat. thirty-two individuals participated to produce the data used in this study. each part ... | 2007 | 17265868 |
| the endemic situation of enterobacter aerogenes and enterobacter cloacae: you will only discover what you are looking for. | 2007 | 17275960 | |
| incidence of class a extended-spectrum beta-lactamases in champagne-ardenne (france): a 1 year prospective study. | to assess the frequency and diversity of extended spectrum beta-lactamases (esbls) in the champagne-ardenne region france, and to identify genetic elements associated with the bla(ctx-m) genes. | 2007 | 17804424 |
| evolutionary conservation of p-selectin glycoprotein ligand-1 primary structure and function. | p-selectin glycoprotein ligand-1 (psgl-1) plays a critical role in recruiting leukocytes in inflammatory lesions by mediating leukocyte rolling on selectins. core-2 o-glycosylation of a n-terminal threonine and sulfation of at least one tyrosine residue of psgl-1 are required for l- and p-selectin binding. little information is available on the intra- and inter-species evolution of psgl-1 primary structure. in addition, the evolutionary conservation of selectin binding site on psgl-1 has not bee ... | 2007 | 17868453 |
| the use of ultrasonic imaging to evaluate the effect of protozoan grazing and movement on the topography of bacterial biofilms. | this study evaluated the effect of protozoan movement and grazing on the topography of a dual-bacterial biofilm using both conventional light microscopy and a new ultrasonic technique. | 2007 | 17897377 |
| medicinal smoke reduces airborne bacteria. | this study represents a comprehensive analysis and scientific validation of our ancient knowledge about the effect of ethnopharmacological aspects of natural products' smoke for therapy and health care on airborne bacterial composition and dynamics, using the biolog microplate panels and microlog database. we have observed that 1h treatment of medicinal smoke emanated by burning wood and a mixture of odoriferous and medicinal herbs (havan sámagri=material used in oblation to fire all over india) ... | 2007 | 17913417 |
| high diversity of extended-spectrum beta-lactamases among clinical isolates of enterobacteriaceae from portugal. | to investigate the occurrence and the diversity of ambler class a esbls among enterobacteriaceae from different portuguese clinical settings over a 2 year period (2002-04). | 2007 | 17913717 |
| nitrosative stress treatment of e. coli targets distinct set of thiol-containing proteins. | reactive nitrogen species (rns) function as powerful antimicrobials in host defence, but so far little is known about their bacterial targets. in this study, we set out to identify escherichia coli proteins with rns-sensitive cysteines. we found that only a very select set of proteins contain cysteines that undergo reversible thiol modifications upon nitric oxide (no) treatment in vivo. of the 10 proteins that we identified, six (atpa, acef, fabb, gapa, ilvc, tufa) have been shown to harbour fun ... | 2007 | 17919278 |
| carbapenemases: molecular diversity and clinical consequences. | carbapenemases are beta-lactamases that hydrolyze most beta-lactams including carbapenems. carbapenemases are classified in four molecular classes; those belonging to class a are the chromosomally-encoded and clavulanic acid-inhibited imi, nmc-a and sme, identified in enterobacter cloacae and serratia marcescens; the plasmid-encoded kpc enzymes identified in enterobacteriaceae (and rarely in pseudomonas aeruginosa); and the ges-type enzymes identified in enterobacteriaceae and p. aeruginosa. the ... | 2007 | 17927473 |
| preliminary investigations on inducing salt tolerance in maize through inoculation with rhizobacteria containing acc deaminase activity. | twenty rhizobacterial strains containing 1-aminocyclopropane-1-carboxylate deaminase were isolated from the rhizosphere of salt-affected maize fields. they were screened for their growth-promoting activities under axenic conditions at 1, 4, 8, and 12 ds x m-1 salinity levels. based upon the data of the axenic study, the 6 most effective strains were selected to conduct pot trials in the wire house. besides one original salinity level (1.6 ds x m-1), 3 other salinity levels (4, 8, and 12 ds x m-1 ... | 2007 | 18026206 |
| mathematical modeling and assessment of microbial migration during the sprouting of alfalfa in trays in a nonuniformly contaminated seed batch using enterobacter aerogenes as a surrogate for salmonella stanley. | raw seed sprouts have been implicated in several food poisoning outbreaks in the past 10 years. the u.s. food and drug administration recommends that sprout growers use interventions (such as testing of spent irrigation water) to control the presence of pathogens in the finished product. during the sprouting process, initially low concentrations of pathogen may increase, and contamination may spread within a batch of sprouting seeds. a model of pathogen growth as a function of time and distance ... | 2007 | 18044441 |
| comparative efficacy of two doses of nebulized colistimethate in the eradication of pseudomonas aeruginosa in children with cystic fibrosis. | cystic fibrosis (cf) affects the respiratory and digestive systems. it evolves toward deterioration of pulmonary function through colonization with pseudomonas aeruginosa. there is no consensus with respect to its eradication. nebulized colistimethate is used for eradication treatment, but the optimal dose and duration is yet to be determined. | 2007 | 18060092 |
| bioproduction of d-psicose from allitol with enterobacter aerogenes ik7: a new frontier in rare ketose production. | d-psicose, a new alternative sweetener, was produced from allitol by microbial oxidation of the newly isolated strain enterobacter aerogenes ik7. cells grown in tryptic soy broth medium (tsb) supplemented with d-mannitol at 37 degrees c were found to have the best oxidation potential. the cells, owing to broad substrate specificity, oxidized various polyols (tetritol, pentitol, and hexitol) to corresponding rare ketoses. by a resting cell reaction, 10% of allitol was completely transformed to th ... | 2007 | 18071247 |
| the enterobacter aerogenes outer membrane efflux proteins tolc and eefc have different channel properties. | the outer membrane proteins tolc and eefc from enterobacter aerogenes are involved in multidrug resistance as part of two resistance-nodulation-division efflux systems. to gain more understanding in the molecular mechanism underlying drug efflux, we have undertaken an electrophysiological characterization of the channel properties of these two proteins. tolc and eefc were purified in their native trimeric form and then reconstituted in proteoliposomes for patch-clamp experiments and in planar li ... | 2007 | 17658457 |
| prevalence and diversity of qnr alleles in ampc-producing enterobacter cloacae, enterobacter aerogenes, citrobacter freundii and serratia marcescens: a multicentre study from korea. | to investigate the prevalence of qnr determinants, their influence on quinolone susceptibility and their association with other plasmid-mediated genes in ampc-producing enterobacteriaceae without any selection criteria. | 2007 | 17660263 |
| thermodynamics of ni2+, cu2+, and zn2+ binding to the urease metallochaperone uree. | the two ni2+ ions in the urease active site are delivered by the metallochaperone uree, whose metal binding properties are central to the assembly of this metallocenter. isothermal titration calorimetry (itc) has been used to quantify the stoichiometry, affinity, and thermodynamics of ni2+, cu2+, and zn2+ binding to the well-studied c-terminal truncated h144*uree from klebsiella aerogenes, ni2+ binding to the wild-type k. aerogenes uree protein, and ni2+ and zn2+ binding to the wild-type uree pr ... | 2007 | 17711301 |
| antimicrobial resistance among gram-negative bacilli causing infections in intensive care unit patients in the united states between 1993 and 2004. | during the 12-year period from 1993 to 2004, antimicrobial susceptibility profiles of 74,394 gram-negative bacillus isolates recovered from intensive care unit (icu) patients in united states hospitals were determined by participating hospitals and collected in a central location. mics for 12 different agents were determined using a standardized broth microdilution method. the 11 organisms most frequently isolated were pseudomonas aeruginosa (22.2%), escherichia coli (18.8%), klebsiella pneumoni ... | 2007 | 17715376 |
| diversity of microflora in the gut and casts of tropical composting earthworms reared on different substrates. | the diversity of fungi, bacteria, yeast, actinomycetes and protozoa were analysed in the gut and casts of eudrilus eugeniae, lampito mauritii, eisenia fetida and perionyx excavatus, both qualitatively and quantitatively as influenced by different feed substrates like clay loam soil, cowdung and pressmud. while actinomycetes (streptomyces albus, s. somaliensis, nocardia asteroides, n. caviae and saccharomonosporia) were not digested by any of these species of worms, protozoa (amoeba proteus, a. t ... | 2007 | 17717992 |
| growth of acanthamoeba castellanii and hartmannella vermiformis on live, heat-killed and dtaf-stained bacterial prey. | the growth responses of two species of amoeba were evaluated in the presence of live, heat-killed and heat-killed/5-(4,6-dichlorotriazin-2-yl) aminofluorescein (dtaf)-stained cells of escherichia coli, pseudomonas aeruginosa, klebsiella aerogenes, klebsiella ozaenae and staphylococcus aureus. the specific growth rates of both species were significantly higher with live bacterial prey, the only exception being hartmannella vermiformis feeding on s. aureus, for which growth rates were equivalent o ... | 2007 | 17596189 |
| characterization of a phosphodiesterase capable of hydrolyzing ea 2192, the most toxic degradation product of the nerve agent vx. | glycerophosphodiesterase (gpdq) from enterobacter aerogenes is a nonspecific diesterase that enables escherichia coli to utilize alkyl phosphodiesters, such as diethyl phosphate, as the sole phosphorus source. the catalytic properties of gpdq were determined, and the best substrate found was bis(p-nitrophenyl) phosphate with a kcat/km value of 6.7 x 10(3) m-1 s-1. in addition, the e. aerogenes diesterase was tested as a catalyst for the hydrolysis of a series of phosphonate monoesters which are ... | 2007 | 17630782 |
| cloning, nucleotide sequencing, and analysis of the acrab-tolc efflux pump of enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. | enterobacter cloacae is an emerging clinical pathogen that may be responsible for nosocomial infections. management of these infections is often difficult, owing to the high frequency of strains that are resistant to disinfectants and antimicrobial agents in the clinical setting. multidrug efflux pumps, especially those belonging to the resistance-nodulation-division family, play a major role as a mechanism of antimicrobial resistance in gram-negative pathogens. in the present study, we cloned a ... | 2007 | 17638702 |
| [resistance to the latest beta-lactams: mechanisms of acquisition and spread of resistance in enterobacteriaceae]. | resistance to antibiotics may drastically diminish the efficacy of therapy in some clinical circumstances. the emergence of enterobacteriaceae (klebsiella pneumoniae, aerobacter aerogenes, escherichia coli) resistant to the more recent beta-lactam agents (cefepime, cefpirome, azthreonam and carbapenems) generally results from misuse of antibiotics, leading to the selection of preexisting resistant mutants. resistance is usually due to beta-lactamase expression, through: -- mutations involving th ... | 2007 | 17645106 |
| periodontal disease as reservoir for multi-resistant and hydrolytic enterobacterial species. | this investigation aimed to isolate enteric rods from subgingival sites of patients presenting chronic periodontitis lesions, and to assess antimicrobial resistance and expression of hydrolytic enzymes. | 2007 | 17451514 |
| inhibition of hydrogen uptake in escherichia coli by expressing the hydrogenase from the cyanobacterium synechocystis sp. pcc 6803. | molecular hydrogen is an environmentally-clean fuel and the reversible (bi-directional) hydrogenase of the cyanobacterium synechocystis sp. pcc 6803 as well as the native escherichia coli hydrogenase 3 hold great promise for hydrogen generation. these enzymes perform the simple reaction 2h+ + 2e- <--> h2 (g). | 2007 | 17521447 |
| substrate specificity of the oqxab multidrug resistance pump in escherichia coli and selected enteric bacteria. | a plasmid-encoded multidrug efflux pump, oqxab, identified in escherichia coli of porcine origin, was tested for substrate specificity against selected antibiotics, detergents and disinfectants. the ability of horizontal transfer to food-borne pathogens of the enterobacteriaceae family was also investigated. | 2007 | 17526501 |
| pyocyanin alters redox homeostasis and carbon flux through central metabolic pathways in pseudomonas aeruginosa pa14. | the opportunistic pathogen pseudomonas aeruginosa produces colorful, redox-active antibiotics called phenazines. excretion of pyocyanin, the best-studied natural phenazine, is responsible for the bluish tint of sputum and pus associated with p. aeruginosa infections in humans. although the toxicity of pyocyanin for other bacteria, as well as its role in eukaryotic infection, has been studied extensively, the physiological relevance of pyocyanin metabolism for the producing organism is not well u ... | 2007 | 17526704 |
| effect of some nitrosative agents on the growth of vgb-bearing enterobacter aerogenes strains. | the effect of transnitrosation intermediate between s-nitroso-n-acetylcysteine (nacysno) and cysteine on the growth of vgb-bearing enterobacter aerogenes was investigated using three parameters: the ratio of the specific growth rates, the inhibition zone, and alpha-amylase synthesis for the culture exposed to stressors to that of the same stressor-free cultures. the effect of nacysno/cysteine on the growth of enterobacter strains was distinctive as compared with the cysno, nacysno, and their com ... | 2007 | 17534561 |
| the first agmatine/cadaverine aminopropyl transferase: biochemical and structural characterization of an enzyme involved in polyamine biosynthesis in the hyperthermophilic archaeon pyrococcus furiosus. | we report here the characterization of the first agmatine/cadaverine aminopropyl transferase (acapt), the enzyme responsible for polyamine biosynthesis from an archaeon. the gene pf0127 encoding acapt in the hyperthermophile pyrococcus furiosus was cloned and expressed in escherichia coli, and the recombinant protein was purified to homogeneity. p. furiosus acapt is a homodimer of 65 kda. the broad substrate specificity of the enzyme toward the amine acceptors is unique, as agmatine, 1,3-diamino ... | 2007 | 17545282 |
| peptide nucleic acid fluorescence in situ hybridization for rapid detection of klebsiella pneumoniae from positive blood cultures. | this study evaluated a novel peptide nucleic acid (pna) probe targeting a region of the 23s rrna gene of klebsiella pneumoniae by fluorescence in situ hybridization (fish). analytical performance was determined using 39 reference strains and other well-characterized strains of klebsiella spp. and enterobacter aerogenes. the probe was found to be specific for the k. pneumoniae complex (k. pneumoniae including klebsiella ozaenae and klebsiella variicola). the diagnostic accuracy was evaluated with ... | 2007 | 17577055 |
| antibacterial activity of bioconverted eicosapentaenoic (epa) and docosahexaenoic acid (dha) against foodborne pathogenic bacteria. | the antimicrobial activity of bioconversion extracts of epa and dha against a range of foodborne pathogenic bacteria was investigated. the bioconverted epa and dha exhibited antibacterial activities against four gram-positive bacteria, bacillus subtilis, listeria monocytogenes, staphylococcus aureus (atcc 6538) and s. aureus (kctc 1916) and seven gram-negative bacteria, enterobacter aerogenes, escherichia coli, e. coli o157:h7, e. coli o157:h7 (human), pseudomonas aeruginosa, salmonella enteriti ... | 2007 | 16860896 |
| [antimicrobial effect of 4-(adamantyl-1)-1-(1-aminobutyl)benzol]. | antimicrobial activity in vitro of adamantine derivative in respect of aerobic and anaerobic microorganisms has been studied. in these conditions gram-positive bacteria and some representatives of gram-negative microorganisms (shigella flexneri, s. newvcastle, enterobacter aerogenes etc.) had maximal sensitivity (mic 0.6-5.0 and 0.1-5.0 mg/ml, respectively). pseudomonas aeruginosa were resistant to this substance (mic >1 mg/ml). | 2007 | 18217353 |
| decontamination effects of low-temperature plasma generated by corona discharge. part ii: new insights. | the second part of our paper presents the results of experiments with the decontamination of surfaces by low-temperature plasma generated by corona discharge in air at atmospheric pressure. a simple device is described and the effects of the corona discharge on model microorganisms, viz. the yeast candida albicans, gram-negative bacteria escherichia coli, enterobacter aerogenes, neisseria sicca, stenotrophomonas maltophilia, gram-positive bacteria deinococcus radiodurans, enterococcus faecium, s ... | 2007 | 18225640 |
| single daily high-dose tigecycline therapy of a multidrug-resistant (mdr) klebsiella pneumoniae and enterobacter aerogenes nosocomial urinary tract infection. | 2007 | 18230562 | |
| [bacteriological study on adult chronic sinusitis operated after endoscopic sinus surgery]. | to explore the bacteria isolated from middle nasal meatus, maxillary sinus, ethmoid sinus and postoperative cavity of patients with chronic rhinosinusitis and their characteristics of antibiotic resistance. | 2007 | 18335747 |
| plasmid mediated antibiotic resistance in marine bacteria. | this research work was conducted in uppanar estuary to ascertain the role of plasmids in the antibiotic resistance of bacteria. water and sediment samples were collected for a period of three months. when tested against 20 antibiotics 22 mar strains were isolated from the samples, which were found resistant to 5-13 antibiotics. they belong to 7 genera and 10 species. gram-negative bacteria namely neisseria mucosa, n. sicca, branhamella catarrhalis, klebsiella ozaenae, citrobacterintermedius, pse ... | 2007 | 18380085 |
| application of pcr ribotyping and tdna-pcr for klebsiella pneumoniae identification. | pcr analysis of 16s-23s internal transcribed spacer (pcr ribotyping) and trna intergenic spacer (tdna-pcr) were evaluated for their effectiveness in identification of clinical strains of klebsiella pneumoniae and differentiation with related species. for this purpose both methods were applied to forty-three clinical isolates biochemically identified as k. pneumoniae subsp. pneumoniae isolated from patients clinical specimens attended at five hospitals in three brazilian cities. references strain ... | 2007 | 17992365 |
| [detection of ampc beta-lactamases in gram-negative bacteria isolated from urine]. | ampc beta-lactamases, enzymes produced by a range of gram-negative bacteria and able to hydrolyse penicillins, monobactams, cephalosporins and cephamycins, are not inhibited by beta-lactamase inhibitors. they are spread via plasmids and pose a huge epidemiological and diagnostic problem. the production of ampc b-lactamases was tested in various gram-negative bacteria. of strains isolated from urine of patients diagnosed with urinary tract infection, we selected those that were resistant to third ... | 2008 | 19069027 |
| update on antimicrobial susceptibility rates among gram-negative and gram-positive organisms in the united states: results from the tigecycline evaluation and surveillance trial (test) 2005 to 2007. | the tigecycline evaluation and surveillance trial (ttest) is a global surveillance study initiated in 2004.its goal is to assess the in vitro activity of the glycylcycline, tigecycline, and comparator antimicrobials. objective: the aim of this study was to measure the in vitro activity of a panel of antimicrobial agents against gram-negative and gram-positive organisms collected in the united states in 2005, 2006, and 2007. | 2008 | 19108792 |
| direct production of l-tagatose from l-psicose by enterobacter aerogenes 230s. | l-tagatose was produced directly from l-psicose by subjecting the same biomass suspension to microbial reduction followed by oxidation using a newly isolated bacteria enterobacter aerogenes 230s. after various optimizations, it was observed that cells grown on xylitol have the best conversion potential. moreover, e. aerogenes 230s converted l-psicose to l-tagatose at a faster rate in the presence of polyols such as glycerol, d-sorbitol, ribitol, l-arabitol, d-mannitol and xylitol. at 5% substrat ... | 2008 | 19111643 |
| bacterial indicators of pollution of the douala lagoon, cameroon: public health implications. | indiscriminate disposal of untreated wastes which are often heavily laden with sewage microorganisms some of which are pathogenic to humans into aquatic environments near cities could serve as potential dangers to human health. | 2008 | 19357756 |
| evaluation of phytochemical and antibacterial potential of helicteres isora l. fruits against enteric bacterial pathogens. | antibacterial activities of aqueous, acetone, ethanol and methanol extracts of fruits of helicteres isora (mororphali) were studied. the fruit aqueous extracts of h. isora showed prominent antibacterial activities against e. coli, staphylococcus epidermidis, salmonella typhimurium and proteus vulgaris; moderate activity against enterobacter aerogenes, staphylococcus aureus, salmonella typhi and least activity against pseudomonas aeruginosa. the aqueous extract showed maximal, the ethanol and met ... | 2008 | 20161950 |
| antibacterial activity of some medicinal plant extracts. | antibacterial activity of hot aqueous and methanolic extracts prepared from six plants (terminallia chebula, terminallia bellerica, phyllanthus emblica, punica granatum, lawsonia alba and mikania micrantha) used in traditional folk medicines of india were screened against five pathogenic bacteria (staphylococcus aureus mtcc 2940, bacillus subtilis mtcc 441, escherichia coli mtcc 739, proteus vulgaris mtcc 426 and enterobacter aerogenes mtcc 111). the highest antibacterial potentiality was exhibi ... | 2008 | 18404337 |
| a versatile plasmid biosensor useful to identify quorum sensing luxr-family orphans in bacterial strains. | eight luxi-family gene promoters (luxi, cvii, ahli, rhli, cepi, phzi, trai and ppui) were cloned in tandem, upstream a promoterless lacz gene in a promoter probe vector yielding pmultiahlprom. this unique construct is useful in determining whether a bacterial strain not producing n-acyl homoserine lactone signal molecules (ahls) possesses orphan luxr type proteins able to respond to ahls and activate transcription from quorum sensing target genes. using pmultiahlprom, it was demonstrated that en ... | 2008 | 18420295 |
| construction of two lux-tagged hg2+-specific biosensors and their luminescence performance. | two hg2+-specific biosensors were constructed using bacterial luciferase as reporter gene and plasmid-free pseudomonas putida x4 and enterobacter aerogenes ntg-01 as host strains. the performance of x4 biosensor was compared with that of ntg-01 biosensor in the same assay conditions. the maximum bioluminescence for x4 (pmerrluxcdabe-kan) biosensor was found during the midexponential phase and that for ntg-01 (pmerrluxcdabe-kan) was at the late exponential phase. the shortest induction time of tw ... | 2008 | 18437376 |
| effect of linear alkylbenzene sulfonates on the growth of aerobic heterotrophic cultivable bacteria isolated from an agricultural soil. | an enrichment culture technique was used to isolate soil bacteria capable of growing in the presence of two different concentrations of linear alkylbenzene sulfonates (las) (10 and 500 microg ml(-1)). nine bacterial strains, representatives of the major colony types of aerobic heterotrophic cultivable bacteria in the enriched samples, were isolated and subsequently identified by pcr-amplification and partial sequencing of the 16s rrna gene. amongst the isolates, strains las05 (pseudomonas syring ... | 2008 | 18443905 |
| antimicrobial activity and synergism of some substituted flavonoids. | natural and synthetic substituted chalcones, flavones and flavanones were tested for antibacterial activity. in order to determine synergism, new combinations of substituted flavonoids against staphylococcus aureus, escherichia coli and enterobacter aerogenes were assayed. the results allow us to establish relationships between antimicrobial effect of the compounds and membrane structures of these microorganisms. when flavonoid combinations were employed a stronger effect was found against e. co ... | 2008 | 18481214 |
| fluoroquinolone resistance during 2000-2005: an observational study. | moxifloxacin is a respiratory fluoroquinolone with a community acquired pneumonia indication. unlike other fluoroquinolones used in our healthcare system, moxifloxacin's urinary excretion is low and thus we hypothesized that increased use of moxifloxacin is associated with an increase in fluoroquinolone resistance amongst gram negative uropathogens. | 2008 | 18501015 |
| cadmium(ii) complexes of the glycerophosphodiester-degrading enzyme gpdq and a biomimetic n,o ligand. | the glycerophosphodiester-degrading enzyme gpdq from enterobacter aerogenes is a promising bioremediator owing to its ability to degrade some organophosphate pesticides and diester products originating from the hydrolysis of nerve agents such as vx. here, the cadmium derivative of gpdq was prepared by reconstituting the apoenzyme. catalytic measurements with (cd(2+))(2)-gpdq and the phosphodiester substrate bis(4-nitrophenyl)phosphate yield k(cat) = 15 s(-1). the pk(a) of 9.4, determined from th ... | 2008 | 18535849 |
| evaluation of reuterin production in urogenital probiotic lactobacillus reuteri rc-14. | classified as a distinct species in 1980, lactobacillus reuteri strains have been used in probiotic formulations for intestinal and urogenital applications. in the former, the primary mechanism of action of l. reuteri sd2112 (atcc 55730) has been purported to be its ability to produce the antibiotic 3-hydroxypropionaldehyde (3-hpa), also known as reuterin. in the vagina, it has been postulated that probiotic lactobacillus reuteri rc-14 does not require reuterin production but mediates a restorat ... | 2008 | 18539802 |
| influence of extended-spectrum beta-lactams on gram-negative bacterial resistance. | the influence of extended- spectrum beta-lactams on gram-negative bacterial resistance was studied. | 2008 | 18541686 |
| successive emergence of extended-spectrum beta-lactamase-producing and carbapenemase-producing enterobacter aerogenes isolates in a university hospital. | sixty-two clinical isolates of enterobacter aerogenes resistant to expanded-spectrum cephalosporins were collected between july 2003 and may 2005. among these isolates, 23 (37.1%) were imipenem (ipm) susceptible, and 39 (62.9%) were ipm insusceptible, of which 89.7% (35/39) were resistant and 10.3% (4/39) were intermediate. isolate genotypes were compared by pulsed-field gel electrophoresis. of 62 isolates, 48 belonged to epidemic pulsotype a (77.4%). this pulsotype included 37.5% and 58.4% of b ... | 2008 | 18234876 |
| molecular and descriptive epidemiologyof multidrug-resistant enterobacteriaceae in hospitalized infants. | to investigate the epidemiology of multidrug-resistant enterobacteriaceae (mdre) in hospitalized infants. | 2008 | 18251685 |
| clinical experience of serious infections caused by enterobacteriaceae producing vim-1 metallo-beta-lactamase in a greek university hospital. | the dissemination of acquired metallo-beta-lactamases (mbls) in members of the family enterobacteriaceae is regarded as an emerging clinical threat. the clinical characteristics and outcomes of 17 cases of infection due to mbl-producing isolates were analyzed. | 2008 | 18269335 |
| viper metalloproteinase (agkistrodon halys pallas) with antimicrobial activity against multi-drug resistant human pathogens. | metalloproteinases are abundant enzymes in crotalidae and viperidae snake venoms. snake venom metalloproteinases (svmps) comprise a family of zinc-dependent enzymes, which display many different biological activities. a 23.1 kda protein was isolated from agkistrodon halys (pallas, chinese viper) snake venom. the toxin is a single chain polypeptide with a molecular weight of 23146.61 and an n-terminal sequence (miqvllvticlavfpyqgssiiles) relatively similar to that of other metalloprotein-like pro ... | 2008 | 18297685 |
| occurrence of esbl & amp-c beta-lactamases & susceptibility to newer antimicrobial agents in complicated uti. | production of extended spectrum beta-lactamases (esbls) and ampc beta-lactamases are the most common mechanisms of antimicrobial resistance in gram negative bacilli. a prospective study was undertaken to know the occurrence of esbl and ampc producing strains and their antibiotic susceptibilities to newer agents to guide empirical therapy for complicated urinary tract infections. | 2008 | 18316858 |
| hypoxia-independent activation of hif-1 by enterobacteriaceae and their siderophores. | hypoxia inducible factor-1 (hif-1) is the key transcriptional regulator during adaptation to hypoxia. recent studies provide evidence for hif-1 activation during bacterial infections. however, molecular details of how bacteria activate hif-1 remain unclear. here, we pursued the role of bacterial siderophores in hif-1 activation during infection with enterobacteriaceae. | 2008 | 18325389 |
| induction of nucleoside phosphorylase in enterobacter aerogenes and enzymatic synthesis of adenine arabinoside. | nucleoside phosphorylases (npases) were found to be induced in enterobacter aerogenes dgo-04, and cytidine and cytidine 5'-monophosphate (cmp) were the best inducers. five mmol/l to fifteen mmol/l cytidine or cmp could distinctly increase the activities of purine nucleoside phosphorylase (pnpase), uridine phosphorylase (upase) and thymidine phosphorylase (tpase) when they were added into medium from 0 to 8 h. in the process of enzymatic synthesis of adenine arabinoside from adenine and uracil ar ... | 2008 | 18600781 |
| nationwide study of the prevalence, characteristics, and molecular epidemiology of extended-spectrum-beta-lactamase-producing enterobacteriaceae in france. | among 10,872 isolates of enterobacteriaceae from a nationwide study of 88 french hospitals in 2005, 169 (1.7%) expressed an extended-spectrum beta-lactamase. the most prevalent species were escherichia coli (48.5%), enterobacter aerogenes (23.7%), and klebsiella pneumoniae (14.8%). molecular analysis underlined the polyclonal spread of ctx-m-expressing e. coli, primarily isolates of the ctx-m-1 subgroup. | 2008 | 18025119 |
| combined physico-chemical treatments based on enterocin as-48 for inactivation of gram-negative bacteria in soybean sprouts. | enterocin as-48 was tested for decontamination of soybean sprouts against gram-negative bacteria. although treatment with bacteriocin alone had no effect on salmonella enterica, a synergistic antimicrobial effect was detected at ph 9.0 and in combination with moderate heat treatment. greatest inactivation was achieved for sprouts heated for 5 min at 65 degrees c in an alkaline (ph 9.0) enterocin as-48 solution of 25 microg/ml. bactericidal activity against s. enterica increased greatly when ente ... | 2008 | 18577412 |
| efficacy of contact lens systems against recent clinical and tap water acanthamoeba isolates. | a recent increase in acanthamoeba keratitis (ak) cases has been associated with complete moistureplus, although many cases used other solutions. complete moistureplus contains taurine and hydroxypropyl methylcellulose, unlike other multipurpose solutions (mpss). the purpose of this study is to (1) determine contact lens solution efficacy against recent clinical and tap water acanthamoeba isolates and (2) determine whether taurine inclusion increases acanthamoeba survival against contact lens sol ... | 2008 | 18580265 |
| dictyostelium transcriptional responses to pseudomonas aeruginosa: common and specific effects from pao1 and pa14 strains. | pseudomonas aeruginosa is one of the most relevant human opportunistic bacterial pathogens. two strains (pao1 and pa14) have been mainly used as models for studying virulence of p. aeruginosa. the strain pa14 is more virulent than pao1 in a wide range of hosts including insects, nematodes and plants. whereas some of the differences might be attributable to concerted action of determinants encoded in pathogenicity islands present in the genome of pa14, a global analysis of the differential host r ... | 2008 | 18590548 |
| in vivo development of carbapenem resistance in clinical isolates of enterobacter aerogenes producing multiple beta-lactamases. | four clinical strains of extended-spectrum beta-lactamase- and ampc-producing enterobacter aerogenes were isolated successively from a liver transplantation patient. isolates c(1) and c(2) were isolated prior to carbapenem therapy, whilst isolates c(3) and c(4) were recovered after 40 days of carbapenem therapy. the homology of these strains was analysed by pulsed-field gel electrophoresis (pfge). beta-lactamases were analysed by isoelectric focusing, polymerase chain reaction (pcr) and sequenci ... | 2008 | 18556176 |
| maintenance metabolism and carbon fluxes in bacillus species. | abstract: | 2008 | 18564406 |
| the culture site of the gallbladder affects recovery of bacteria in symptomatic cholelithiasis. | traditional methods for bile culturing may miss a large number of underlying bacterial infections that could lead to acute or chronic cholecystitis. | 2008 | 18568139 |
| antibacterial and preliminary phytochemical and physico-chemical analysis of eucalyptus citriodora hk leaf. | the present communication deals with some studies on the antibacterial, physico-chemical and phytochemical parameters of different extracts of eucalyptus citriodora leaf. the antibacterial study was performed using the agar ditch method on some clinically important bacteria, namely pseudomonas pseudoalcaligenes, proteus vulgaris, citrobacter freundii, staphylococcus subflava, bacillus megaterium, and enterobacter aerogenes. physico-chemical parameters namely water, methanol, 1,4-dioxane, dmf, ac ... | 2008 | 18569717 |
| synthesis and in-vitro antibacterial activity of 5-substituted 1-methyl-4-nitro-1h-imidazoles. | a series of 5-substituted 1-methyl-4-nitro-1h-imidazole derivatives were synthesized and evaluated for in-vitro antibacterial activity against a panel of microorganisms including staphylococcus aureus, staphylococcus epidermidis, bacillus subtilis, escherichia coli, klebsiella pneumonia, enterobacter aerogenes, and helicobacter pylori using conventional agar dilution method. among the test compounds, 1-methyl-4-nitro-5-(phenylsulfonyl)-1h-imidazole was the most potent against gram-positive bacte ... | 2008 | 18618489 |
| bacteriocin-producing lactobacillus strains isolated from poto poto, a congolese fermented maize product, and genetic fingerprinting of their plantaricin operons. | thirty one bacteriocin-producing lactobacillus isolates were identified among 135 lactobacilli isolated from the congolese fermented maize product poto poto, during the preparation and from the finished product. using species-specific pcr and 16s rrna gene sequencing, 28 and 3 isolates were identified as l. plantarum and l. fermentum, respectively. cluster analysis of rapd-pcr fingerprints revealed two main groups (g1 and g2) plus the l. fermentum isolate c4-13. group g1 contained 23 isolates wi ... | 2008 | 18620772 |
| a tripartite efflux pump involved in gastrointestinal colonization by klebsiella pneumoniae confers a tolerance response to inorganic acid. | the colonization of the gastrointestinal tract of patients by the opportunistic gram-negative bacillus klebsiella pneumoniae generally occurs prior to the development of nosocomial infections. mutant strain c-81 was isolated owing to its reduced capacity to colonize the digestive tract in a murine model following transposon mutagenesis (n. maroncle, d. balestrino, c. rich, and c. forestier, infect. immun. 70:4729-4734, 2002). nucleotide sequence analysis showed that the transposon had inserted i ... | 2008 | 18644883 |
| malonate-bound structure of the glycerophosphodiesterase from enterobacter aerogenes (gpdq) and characterization of the native fe2+ metal-ion preference. | the structure of a malonate-bound form of the glycerophosphodiesterase from enterobacter aerogenes, gpdq, has been refined at a resolution of 2.2 a to a final r factor of 17.1%. the structure was originally solved to 2.9 a resolution using sad phases from zn2+ metal ions introduced into the active site of the apoenzyme [jackson et al. (2007), j. mol. biol. 367, 1047-1062]. however, the 2.9 a resolution was insufficient to discern significant details of the architecture of the binuclear metal cen ... | 2008 | 18678932 |
| nxl104 combinations versus enterobacteriaceae with ctx-m extended-spectrum beta-lactamases and carbapenemases. | the beta-lactamase landscape is changing radically, with ctx-m types now the most prevalent extended-spectrum beta-lactamases (esbls) worldwide, except maybe in the usa. in addition, there are growing numbers of enterobacteriaceae with kpc and metallo-carbapenemases. we examined whether combinations of oxyimino-cephalosporins with nxl104, a novel non-beta-lactam beta-lactamase inhibitor, overcame these resistances. | 2008 | 18689875 |
| kinetic flux profiling for quantitation of cellular metabolic fluxes. | this protocol enables quantitation of metabolic fluxes in cultured cells. measurements are based on the kinetics of cellular incorporation of stable isotope from nutrient into downstream metabolites. at multiple time points, after cells are rapidly switched from unlabeled to isotope-labeled nutrient, metabolism is quenched, metabolites are extracted and the extract is analyzed by chromatography-mass spectrometry. resulting plots of unlabeled compound versus time follow variants of exponential de ... | 2008 | 18714301 |
| ethanolamine activates a sensor histidine kinase regulating its utilization in enterococcus faecalis. | enterococcus faecalis is a gram-positive commensal bacterium of the human intestinal tract. its opportunistic pathogenicity has been enhanced by the acquisition of multiple antibiotic resistances, making the treatment of enterococcal infections an increasingly difficult problem. the extraordinary capacity of this organism to colonize and survive in a wide variety of ecological niches is attributable, at least in part, to signal transduction pathways mediated by two-component systems (tcs). here, ... | 2008 | 18776017 |
| membrane permeability and regulation of drug "influx and efflux" in enterobacterial pathogens. | in enterobacteriaceae, membrane permeability is a key in the level of susceptibility to antibiotics. modification of the bacterial envelope by decreasing the porin production or increasing the expression of efflux pump systems has been reported. these phenomena are frequently associated with other resistance mechanisms such as alteration of antibiotics or modification of the drug targets, in various clinical isolates showing a multi drug resistant phenotype (mdr). in escherichia coli, enterobact ... | 2008 | 18781921 |
| identification and evolution of drug efflux pump in clinical enterobacter aerogenes strains isolated in 1995 and 2003. | the high mortality impact of infectious diseases will increase due to accelerated evolution of antibiotic resistance in important human pathogens. development of antibiotic resistance is a evolutionary process inducing the erosion of the effectiveness of our arsenal of antibiotics. resistance is not necessarily limited to a single class of antibacterial agents but may affect many unrelated compounds; this is termed 'multidrug resistance' (mdr). the major mechanism of mdr is the active expulsion ... | 2008 | 18787654 |
| wound healing, anti-microbial and antioxidant potential of dendrophthoe falcata (l.f) ettingsh. | dendrophthoe falcata (l.f) ettingsh (loranthaceae) of the order santalales, is used ethnomedicinally for treating ulcers, asthma, impotence, paralysis, skin diseases, and wounds. in this context, validations of the ethnotherapeutic claims of the plant in wound healing activity was studied, besides anti-microbial activity and antioxidant activity were performed to understand the mechanism of wound healing potency. the ethanolic extract of aerial parts of dendrophthoe falcata ethanolic extract (df ... | 2008 | 18790035 |
| dualistic acidic and neutral glucose fermentation balance in small intestine: simulation in vitro. | intestinal microbes live in diminished or deprived oxygen conditions. facultative anaerobic bacteria of the family enterobacteriaceae ferment glucose in the gut using two main pathways: mixed acid and neutral fermentations. the aim of the present study was to clarify the roles of these fermentations in an in vitro model. acid-producing escherichia coli atcc 25922 and neutral end-products producing klebsiella mobilis atcc 13048 were cultured in a portable microbe enrichment unit (pmeu) which perm ... | 2008 | 18804970 |
| efficacy of plant essential oils against foodborne pathogens and spoilage bacteria associated with ready-to-eat vegetables: antimicrobial and sensory screening. | the objectives of this study were to evaluate the antimicrobial activity of plant essential oils (eos) against foodborne pathogens and key spoilage bacteria pertinent to ready-to-eat vegetables and to screen the selected eos for sensory acceptability. the eos basil, caraway, fennel, lemon balm, marjoram, nutmeg, oregano, parsley, rosemary, sage, and thyme were evaluated. the bacteria evaluated were listeria spp., staphylococcus aureus, lactobacillus spp., bacillus cereus, salmonella, enterobacte ... | 2008 | 18810868 |
| digestion of rice straw and oil palm fronds by microflora from rumen and termite bacteria, in vitro. | the digestion and volatile fatty acid (vfa) production from rice straw and oil palm fronds by cellulolytic bacteria isolated from the termite coptotermes curvignathus were investigated. the bacteria were acinetobacter strain raminalimon, enterobacter aerogenes strain razmin c, enterobacter cloacae strain razmin b, bacillus cereus strain razmin a and chryseobacterium kwangyangense strain cb. acinetobacter strain raminalimon is an aerobic bacterium, while the other species are facultative anaerobe ... | 2008 | 18817130 |
| the structure of urease activation complexes examined by flexibility analysis, mutagenesis, and small-angle x-ray scattering. | conformational changes of klebsiella aerogenes urease apoprotein (ureabc)(3) induced upon binding of the ured and uref accessory proteins were examined by a combination of flexibility analysis, mutagenesis, and small-angle x-ray scattering (saxs). proflex analysis of urease provided evidence that the major domain of ureb can move in a hinge-like motion to account for prior chemical cross-linking results. rigidification of the ureb hinge region, accomplished through a g11p mutation, reduced the e ... | 2008 | 18823937 |
| substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from enterobacter aerogenes. | the glycerophosphodiesterase (gpdq) from enterobacter aerogenes is a promiscuous binuclear metallohydrolase that catalyzes the hydrolysis of mono-, di-, and triester substrates, including some organophosphate pesticides and products of the degradation of nerve agents. gpdq has attracted recent attention as a promising enzymatic bioremediator. here, we have investigated the catalytic mechanism of this versatile enzyme using a range of techniques. an improved crystal structure (1.9 a resolution) i ... | 2008 | 18831553 |
| risk of misidentification of enterobacter aerogenes inducible cephalosporinases. | 2008 | 18835042 | |
| experimental and qsar of acetophenones as antibacterial agents. | antibacterial activity of 20 acetophenone derivatives was evaluated against two gram-positive and three gram-negative organisms, namely, bacillus subtilis ncim 2718, staphylococcus aureus ncim5021, salmonella typhi ncim2501, enterobacter aerogenes ncim5139, and proteus vulgaris ncim2813 by two-fold dilution method. the most active amongst this group of compounds were 4-methyl, 2-hydroxy, 3-bromo, 4-ethoxy, 3-nitro and 4-nitro acetophenones. quantitative structure-activity relationships were deve ... | 2008 | 18844677 |
| [recent evolution and characterization of extended-spectrum beta-lactamase producing enterobacteria in the chu of nice (2005-2007)]. | esbl producing enterobacteria (e-esbl+) are always a public health concern, mainly due to increase of ctx-m beta-lactamase. so, 542 new strains were isolated in the chu de nice during the 2005-2007 period. the aim of this work was to characterize the esbl and to type isolates suspected to be implicated in outbreaks. | 2008 | 18848404 |
| optimization of key process variables for enhanced hydrogen production by enterobacter aerogenes using statistical methods. | the individual and mutual effects of glucose concentration, temperature and ph on the hydrogen production by enterobacter aerogenes were investigated in a batch system. a box-behnken design and response surface methodology (rsm) were employed to determine the optimum condition for enhanced hydrogen production. the hydrogen production rate was investigated by simultaneously changing the three independent variables, which all had significant influences on the hydrogen production rate. the maximum ... | 2008 | 17582761 |
| the distribution of acetohydroxyacid synthase in soil bacteria. | most bacteria possess the enzyme acetohydroxyacid synthase, which is used to produce branched-chain amino acids. enteric bacteria contain several isozymes suited to different conditions, but the distribution of acetohydroxyacid synthase in soil bacteria is largely unknown. growth experiments confirmed that escherichia coli, salmonella enterica serotype typhimurium, and enterobacter aerogenes contain isozymes of acetohydroxyacid synthase, allowing the bacteria to grow in the presence of valine (w ... | 2008 | 17624809 |
| hydrogen and polyhydroxybutyrate producing abilities of microbes from diverse habitats by dark fermentative process. | thirty five bacterial isolates from diverse environmental sources such as contaminated food, nitrogen rich soil, activated sludges from pesticide and oil refineries effluent treatment plants were found to belong to bacillus, bordetella, enterobacter, proteus, and pseudomonas sp. on the basis of 16s rrna gene sequence analysis. under dark fermentative conditions, maximum hydrogen (h(2)) yields (mol/mol of glucose added) were recorded to be 0.68 with enterobacter aerogenes egu16 followed by 0.63 w ... | 2008 | 18083024 |
| e240v substitution increases catalytic efficiency toward ceftazidime in a new natural tem-type extended-spectrum beta-lactamase, tem-149, from enterobacter aerogenes and serratia marcescens clinical isolates. | the aim of this study was to characterize a novel extended-spectrum beta-lactamase that belongs to the tem family, the tem-149 enzyme, and that was isolated from the urine of two hospitalized patients from different hospitals in southern italy. the peculiarity of this enzyme was the finding of a valine residue at position 240. the array of amino acid substitutions found in tem-149 was as follows: e104k, r164s, m182t, and e240v. a reversion of a threonine residue at position 182 was also performe ... | 2008 | 18160520 |
| type 3 fimbriae, encoded by the conjugative plasmid pola52, enhance biofilm formation and transfer frequencies in enterobacteriaceae strains. | the conjugative plasmid pola52, which confers resistance to olaquindox and other antimicrobial agents through a multidrug efflux pump, was investigated for its ability to promote biofilm formation in escherichia coli. screening of a transposon-mutagenized pola52 clone library revealed several biofilm-deficient mutants, which all mapped within a putative operon with high homology to the mrkabcdf operon of klebsiella pneumoniae, where these genes are responsible for type 3 fimbriae expression, att ... | 2008 | 18174137 |
| succession of dominant and antagonistic lactic acid bacteria in fermented cucumber: insights from a pcr-based approach. | the goal of the investigation was to study the succession of major groups of lactic acid bacteria (lab) and their antagonism in salt-fermented cucumber using pcr. in a direct detection method as well as a short enrichment process, pcr enabled detection of leuconostoc and lactobacillus during early hours of fermentation. subsequently, lactobacillus and pediococcus emerged as the dominant genera. nucleic acid sequence of culture-independent clones confirmed the detection of pediococcus as a domina ... | 2008 | 18206770 |
| sperm motility changes after coincubation with various uropathogenic microorganisms: an in vitro experimental study. | we investigated the relationship between semen motility and various uropathogenic microorganisms. | 2008 | 17934792 |
| comparative study of thermostability and ester synthesis ability of free and immobilized lipases on cross linked silica gel. | a novel support has been utilized for immobilization of lipase, which was prepared by amination of silica with ethanolamine followed by cross linking with glutaraldehyde. lipases from rhizopus oryzae 3562 and enterobacter aerogenes were immobilized on activated silica gel, where they retained 60 and 50% of respective original activity. the thermal stability of the immobilized lipases was significantly improved in comparison to the free forms while the ph stability remained unchanged. e. aerogene ... | 2008 | 17882456 |
| horizontol dissemination of tem- and shv-typr beta-lactamase genes-carrying resistance plasmids amongst clonical isolates of enterobacteriaceae. | the extended-spectrum β-lactamase (esbl)-producing bacteria have been isolated at increasing frequency worldwide. expression of esbl is often associated with multidrug resistance and dissemination by resistance plasmids. during a two-month period in 2000, 133 clinical isolates of enterobacterial strains were randomly collected from outpatients and inpatients at a university hospital in turkey. the esbl producing strains were determined by double-disk synergy (dds) testing. twenty esbl producing ... | 2008 | 24031280 |
| species composition of bacterial communities influences attraction of mosquitoes to experimental plant infusions. | in the container habitats of immature mosquitoes, catabolism of plant matter and other organic detritus by microbial organisms produces metabolites that mediate the oviposition behavior of aedes aegypti and aedes albopictus. public health agencies commonly use oviposition traps containing plant infusions for monitoring populations of these mosquito species, which are global vectors of dengue viruses. in laboratory experiments, gravid females exhibited significantly diminished responses to experi ... | 2009 | 19641948 |
| species composition of bacterial communities influences attraction of mosquitoes to experimental plant infusions. | in the container habitats of immature mosquitoes, catabolism of plant matter and other organic detritus by microbial organisms produces metabolites that mediate the oviposition behavior of aedes aegypti and aedes albopictus. public health agencies commonly use oviposition traps containing plant infusions for monitoring populations of these mosquito species, which are global vectors of dengue viruses. in laboratory experiments, gravid females exhibited significantly diminished responses to experi ... | 2009 | 19641948 |
| detecting the form of selection in the outer membrane protein c of enterobacter aerogenes strains and salmonella species. | the types of selective pressure operating on the outer membrane protein c (ompc) of enterobacter aerogenes strains, the causative agent for nosocomial infections, and salmonella sp., the hazardous pathogen are investigated using the maximum likelihood-based codon substitution models. although the rate of amino acid replacement to the silent substitution (omega) across the entire codon sites of ompc of e. aerogenes (omega=0.3194) and salmonella sp. (omega=0.2047) indicate that the gene is subject ... | 2009 | 17418551 |
| ampc beta-lactamases. | summary: ampc beta-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the enterobacteriaceae and a few other organisms, where they mediate resistance to cephalothin, cefazolin, cefoxitin, most penicillins, and beta-lactamase inhibitor-beta-lactam combinations. in many bacteria, ampc enzymes are inducible and can be expressed at high levels by mutation. overexpression confers resistance to broad-spectrum cephalosporins including cefotaxime, ceftazidime, an ... | 2009 | 19136439 |