Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
rapid detection of blaimp-6 by amplification refractory mutation system.klebsiella pneumoniae resistant to almost all ß-lactams except imipenem designated as ismrk (imipenem-susceptible meropenem-resistant klebsiella) is emerging in japan. all ismrk carries bla(imp-6) which differs from bla(imp-1) by only a single nucleotide at position 640. we devised a rapid detection system of bla(imp-6) by using arms pcr.201222108497
ndm-1-producing klebsiella pneumoniae in mauritius. 201222006002
A case of carbapenemase-producing Klebsiella pneumoniae in Australia. 201222157689
characterization of a dha-1-producing klebsiella pneumoniae strain involved in an outbreak and role of the ampr regulator in virulence.a clonal strain of klebsiella pneumoniae producing the plasmid-encoded cephalosporinase dha-1 was isolated from four patients admitted to the teaching hospital of clermont-ferrand, france, in 2006. it was responsible for severe infections in three of the patients; the fourth was colonized only in the gastrointestinal tract. the strain had at least two plasmids encoding resistance to antibiotics (quinolones, aminoglycosides, chloramphenicol, sulfonamides, and trimethoprim), as shown by disk diffu ...201221986829
Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak.Objectives To characterize the complete sequence, horizontal spread and stability of the CTX-M-15-encoding multiresistance plasmid of a Klebsiella pneumoniae strain involved in a large nosocomial outbreak. Methods The 220 kbp plasmid pUUH239.2 was completely sequenced using 454 technology. The conjugational host range, conjugation frequencies, plasmid stability and fitness cost of plasmid carriage were studied in vitro. Conjugational spread during the outbreak was assessed retrospectively by mu ...201221990049
in vitro antimicrobial studies of silver carbene complexes: activity of free and nanoparticle carbene formulations against clinical isolates of pathogenic bacteria.silver carbenes may represent novel, broad-spectrum antimicrobial agents that have low toxicity while providing varying chemistry for targeted applications. here, the bactericidal activity of four silver carbene complexes (sccs) with different formulations, including nanoparticles (nps) and micelles, was tested against a panel of clinical strains of bacteria and fungi that are the causative agents of many skin and soft tissue, respiratory, wound, blood, and nosocomial infections.201221972270
the characteristics of vim-1-producing klebsiella pneumoniae from south africa.abstract a study was designed to characterize a carbapenem-resistant klebsiella pneumoniae (kpsa01) isolated from a patient in gauteng, south africa without recent travel outside south africa. molecular characterization was done using isoelectric focusing, polymerase chain reaction and sequencing for bla(vim), bla(imp), bla(ndm), bla(ctx-ms), bla(oxas), bla(tems), and bla(shv), plasmid-mediated quinolone resistance determinants, multilocus sequencing typing, plasmid replicon typing, and addict ...201221954935
Antimicrobial activities of three species of family mimosaceae.The antimicrobial activities of crude methanolic extract of leaves of Acacia nilotica L., Albizia lebbeck L. and Mimosa himalayana Gamble belonging to family mimosaceae were investigated in this research work. Antibacterial activity was studied by agar well diffusion method against one gram-positive Bacillus subtilis and three gram-negative Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumonia. Crude extract of all plants showed best activity against gram-negative bacterial strains w ...201222186331
Emergence in Japan of an imipenem-susceptible, meropenem-resistant Klebsiella pneumoniae carrying bla(IMP-6).We identified 5 Klebsiella pneumoniae isolates showing high resistance to ß-lactams except imipenem and designated them ISMRK (imipenem-susceptible but meropenem-resistant Klebsiella). They carried the bla(IMP-6) and bla(CTX-M-2) on a self-transmissible plasmid. ISMRK may be falsely categorized as susceptible to carbapenems if imipenem is used to screen carbapenem resistance.201222078906
mobilizable narrow host range plasmids as natural suicide vectors enabling horizontal gene transfer among distantly related bacterial species.klebsiella pneumoniae 287-w carries three small narrow host range (nhr) plasmids (pigms31, pigms32, and pigrk), which could be maintained in several closely related species of gammaproteobacteria, but not in alphaproteobacteria. the plasmids contain different mobilization systems (mob), whose activity in escherichia coli was demonstrated in the presence of the helper transfer system originating from plasmid rk2. the mobs of pigms31 and pigms32 are highly conserved in many bacterial plasmids (mem ...201222092700
characterization of phragmites cummunis rhizosphere bacterial communities and metabolic products during the two stage sequential treatment of post methanated distillery effluent by bacteria and wetland plants.this study deals with the characterization of rhizosphere bacterial communities and metabolic products produced during the two stage sequential treatment of post methanated distillery effluent by bacteria and constructed wetland plants. results showed that bacterial treatment followed by wetland plants (phragmites cummunis) resulted 94.5% and 96.0% reduction in bod and cod values, respectively. the pcr-rflp analysis showed the presence of stenotrophomonas, enterobacter, pantoea, acinetobacter an ...201222047662
A cautionary case of microbial solidarity: concurrent isolation of VIM-1-producing Klebsiella pneumoniae, Escherichia coli and Enterobacter cloacae from an infected wound. 201221969331
Composition and antibacterial activity of essential oil from Scutellaria grossa Wall ex Benth.The chemical composition of the steam volatile oil of the whole aerial part of Scutellaria grossa Wall ex Benth. (Lamiaceae), obtained by steam distillation, has been analysed by capillary GC and GC-MS. The oil was found to be rich in oxygenated monoterpenes (88.6%). A total of 50 constituents were identified, representing 94.4% of the total oil composition. Linalool (37.0%) and 1-octen-3-ol (32.0%) were found to be the principal constituents. The antibacterial activity of the oil was determined ...201222060314
Plasmid-mediated resistance in enterobacteriaceae: changing landscape and implications for therapy.Antimicrobial resistance is increasing worldwide, and pathogenic microorganisms that are resistant to all available antimicrobial agents are increasingly reported. Emerging plasmid-encoded extended-spectrum ß-lactamases (ESBLs) and carbapenemases are increasingly reported worldwide. Carbapenemase production encoded by genes located on mobile genetic elements is typically accompanied by genes encoding resistance to other drug classes, often but not necessarily located on the same mobile element. ...201222191792
Thermal treatment of the bacteriophage lysate of Klebsiella pneumoniae B5055 as a step for the purification of capsular depolymerase enzyme.The lytic bacteriophage which produces the hydrolase enzyme capable of depolymerizing exopolysaccharide of Klebsiella pneumoniae and of other bacteria was isolated earlier. In this study, a simple method of depolymerase purification from the phage lysate by dissociating the enzyme from the phage particle was developed. The bacteriophage showed a relatively smaller plaque size surrounded by a wide halo indicating a depolymerase action on the capsular polysaccharide of K. pneumoniae B5055. The dep ...201222036659
production of 3-hydroxypropionic acid through propionaldehyde dehydrogenase pdup mediated biosynthetic pathway in klebsiella pneumoniae.the pdup gene encodes a propionaldehyde dehydrogenase (pdup) was investigated for the role in 3-hydroxypropionic acid (3-hp) glycerol metabolism in klebsiella pneumoniae. the enzyme assay showed that cell extracts from a pdup mutant strain lacked measurable dehydrogenase activity. additionally, the mutant strain accumulated the cytotoxic intermediate metabolite 3-hydroxypropionaldehyde (3-hpa), causing both cell death and a lower final 3-hp titer. ectopic expression of pdup restored normal cell ...201222018749
emergence of an autochthonous and community-acquired ndm-1-producing klebsiella pneumoniae in europe. 201221960718
Nosocomial Outbreak of VIM-1-Producing Klebsiella pneumoniae Isolates of Multilocus Sequence Type 15: Molecular Basis, Clinical Risk Factors, and Outcome.We study the epidemiology, molecular basis, clinical risk factors, and outcome involved in the clonal dissemination of VIM-1-producing Klebsiella pneumoniae isolates in the hospital setting. All patients infected/colonized by carbapenem-nonsusceptible K. pneumoniae (CNSKP) in 2009 were included. Molecular epidemiology was studied by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Antibiotic resistance genes were analyzed by PCR and sequencing. Plasmids were studied ...201222005997
a randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation.community-acquired pneumonia (cap) is a serious infection requiring hospitalisation in 20% of cases. the novel cephalosporin ceftobiprole has microbiological activity against the major bacterial pathogens causing cap, including streptococcus pneumoniae, haemophilus influenzae and klebsiella pneumoniae, as well as against staphylococcus aureus, including meticillin-resistant s. aureus (mrsa). this was a multicentre, double-blind study in which 706 patients with cap severe enough to require hospit ...201222230331
antimicrobial susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in south african hospitals (smart study 2004-2009): impact of the new carbapenem breakpoints.abstract background: the study for monitoring antimicrobial resistance trends (smart) follows trends in resistance among aerobic and facultative anaerobic gram-negative bacilli (gnb) isolated from complicated intra-abdominal infections (ciais) in patients around the world. methods: during 2004-2009, three centralized clinical microbiology laboratories serving 59 private hospitals in three large south african cities collected 1,218 gnb from complicated intra-abdominal infections (ciais) and t ...201222220506
etiology of acute, non-malaria, febrile illnesses in jayapura, northeastern papua, indonesia.abstract. we conducted a prospective, inpatient fever study in malaria-endemic papua, indonesia to determine non-malaria fever etiologies. investigations included malaria blood films, blood culture, paired serologic samples analysis for dengue, japanese encephalitis, leptospirosis, scrub typhus, murine typhus, and spotted fever group rickettsia. during 1997-2000, 226 patients (127 males and 99 females) 1-80 years of age (median age = 25 years) were enrolled. positive blood cultures (n = 34, 15%) ...201222232450
the role of nutrients in the biodegradation of 2,4,6-trinitrotoluene in liquid and soil.the widely used explosive 2,4,6-trinitrotoluene (tnt) has residues that are potentially explosive, toxic, and mutagenic. tnt and other explosives can be degraded by microorganisms; however, biostimulation is needed for process efficiency. to investigate the effectiveness of using biostimulation to degrade tnt, we added varying concentrations of a nutrient amendment consisting of inorganic salts, plant extracts, and molasses to soil and liquid media. for the inoculum we used a consortium of bacte ...201222245864
chemical compositions of the essential oils of aerial parts of chamaemelum mixtum (l.) alloni.the chemical compositions of the aerial parts essential oils of chamaemelum mixtum (l.) alloni from corsica and sardinia were investigated employing gas chromatography and gas chromatography/mass spectrometry. the structure of (z)-heptadeca-9,16-dien-7-one, a natural compound not previously described, was elucidated by gas chromatography/mass spectrometry (electron impact and chemical ionization) and one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy. the variation in ch ...201222225420
antimicrobial activity of ulopterol isolated from toddalia asiatica (l.) lam.: a traditional medicinal plant.aim of the study: the leaves of toddalia asiatica (l.) lam. (rutaceae) are widely used in folk medicine in india to treat various ailments. in our earlier communication we have reported the antimicrobial study on the various extracts of the leaves and the isolation and identification of flindersine, a quinolone alkaloid as the major active principle. in the present study, we report the antibacterial and antifungal activities of ulopterol, a coumarin isolated as another major active antimicrobial ...201222265751
prevalence of antibiotic resistance in fecal flora of patients undergoing transrectal ultrasound-guided prostate biopsy in thailand.objective: the objective of this study was to determine the prevalence of antibiotic resistance in fecal flora of patients undergoing transrectal ultrasound-guided needle biopsy of the prostate (trusb) and the factors associated with such antibiotic resistance. methods: a prospective study of patients undergoing trusb was conducted. rectal swabs were performed and sent for cultures and antibiotic susceptibility testing before trusb. clinical characteristics were determined. results: 287 gram-neg ...201222269856
klebsiella pneumoniae st258 producing kpc-3 identified in italy carries novel plasmids and ompk36/ompk35 porin variants.a carbapenemase resistant klebsiella pneumoniae strain, clone st258 producing kpc-3 was fully characterized. the entire plasmid content was investigated, identifying plasmids of the incfii(k) (two of them similar to pkpqil and pkpn3, respectively), incx and cole types, encoding for a formidable set of resistance genes against toxic compounds, metals and antimicrobial drugs and a novel iron(iii) uptake system.201222252815
nosocomial clustering of ndm-1-producing klebsiella pneumoniae sequence type 340 in four patients at a korean tertiary care hospital.in november 2010, ndm-1-producing klebsiella pneumoniae (ndmkp) was identified from four patients stayed for 21 to 205 days in a tertiary care hospital with no travelling history abroad, which was first time in korea. all were st340 and had nearly identical xbai-pfge patterns. the bla(ndm-1)-carrying plasmids were inc/rep n group with a variable size of 50-200 kb. these findings suggest that ndmkp had already been introduced into korea before this clustering found.201222259206
klebsiella pneumoniae related community-acquired acute lower respiratory infections in cambodia: clinical characteristics and treatment.abstract: background: in many asian countries, klebsiella pneumoniae (kp) is the second pathogen responsible for community-acquired pneumonia. yet, very little is known about kp etiology in alri in cambodia, a country that has one of the weakest medical infrastructures in the region. we present here the first clinico-radiological description of kp community-acquired alri in hospitalized cambodian patients. methods: through alri surveillance in two provincial hospitals, kp was isolated from sput ...201222233322
phenotypic screening of carbapenemases and associated beta-lactamases in carbapenem-resistant enterobacteriaceae.dissemination of carbapenem resistance among enterobacteriaceae poses a considerable threat to public health. carbapenemase gene detection by molecular methods is the gold standard but is only available in few laboratories. the aim of this study was to test phenotypic methods for the detection of metallo-β-lactamase (mbl)- or klebsiella pneumoniae carbapenemase (kpc)-producing enterobacteriaceae and associated mechanisms of beta-lactam resistance against a panel of 30 genotypically characterized ...201222259214
bronchoscopic findings in children with chronic wet cough.objectives:protracted bacterial bronchitis is defined as the presence of more than 4 weeks of chronic wet cough that resolves with appropriate antibiotic therapy, in the absence of alternative diagnoses. the diagnosis of protracted bacterial bronchitis is not readily accepted within the pediatric community, however, and data on the incidence of bacterial bronchitis in children are deficient. the objective of this study was to determine the frequency of bacterial bronchitis in children with chron ...201222232311
coastal seawater bacteria harbor a large reservoir of plasmid-mediated quinolone resistance determinants in jiaozhou bay, china.diversity and prevalence of plasmid-mediated quinolone resistance determinants were investigated in environmental bacteria isolated from surface seawater of jiaozhou bay, china. five qnr gene alleles were identified in 34 isolates by pcr amplification, including qnra3 gene in a shewanella algae isolate, qnrb9 gene in a citrobacter freundii isolate, qnrd gene in 22 proteus vulgaris isolates, qnrs1 gene in 1 enterobacter sp. and 4 klebsiella spp. isolates, and qnrs2 gene in 1 pseudomonas sp. and 4 ...201222252223
in vitro potential of equine defa1 and ecath1 as alternative antimicrobial drugs in rhodococcosis treatment.rhodococcus equi, the causal agent of rhodococcosis, is a severe pathogen of foals but also of immunodeficient humans causing bronchopneumonia. the pathogen is often found together with klebsiella pneumoniae or streptococcus zooepidemicus in foals. of great concern is the fact that some r. equi strains are already resistant to commonly used antibiotics. in the present study, we evaluated the in vitro potential of two equine antimicrobial peptides (amps), ecath1 and defa1, as new drugs against r. ...201222232283
study of plasmid-mediated extended-spectrum β-lactamase-producing strains of enterobacteriaceae, isolated from diabetic foot infections in a north indian tertiary-care hospital.abstract aim: this study evaluated the incidence and factors responsible for plasmid-mediated extended-spectrum β-lactamase (esbl) infection among patients with diabetic foot ulcer (dfu). subjects and methods: a prospective study was conducted on 162 dfu inpatients treated in a multidisciplinary-based diabetes and endocrinology center at jawaharlal nehru medical college of aligarh muslim university, aligarh, india, during the period of december 2008-march 2011. detailed history and patient's ...201222225456
characterization of a single-stranded dna-binding protein from klebsiella pneumoniae: mutation at either arg73 or ser76 causes a less cooperative complex on dna.single-stranded dna-binding protein (ssb) plays an important role in dna metabolism, such as in processes like dna replication, repair and recombination, and is essential for cell survival. here, we characterized the ssdna-binding properties of klebsiella pneumoniae ssb (kpssb) by using fluorescence-quenching measurements, electrophoretic mobility shift analysis (emsa) and site-directed mutagenesis. analysis of purified kpssb by gel-filtration chromatography showed a stable tetramer in solution. ...201222244199
french results of the aresc study: clinical aspects and epidemiology of antimicrobial resistance in female patients with cystitis. implications for empiric therapy.objective: uncomplicated cystitis is one of the most frequent community infections. we report the french results of the international aresc study on the clinical aspects, epidemiology, and antimicrobial susceptibility of uropathogens. patient and methods: female patients between 18 and 65 years of age, with symptoms of uncomplicated cystitis, were investigated clinically with urinalysis and urine culture. uropathogens were identified and their susceptibility was tested with nine antimicrobials. ...201222264668
characterization of carbapenem-nonsusceptible klebsiella pneumoniae bloodstream isolates at a taiwanese hospital: clinical impacts of lowered breakpoints for carbapenems.this study was conducted in order to characterize carbapenem-nonsusceptible klebsiella pneumoniae isolates and to evaluate the impacts of recently lowered interpretative breakpoints for carbapenems for enterobacteriaceae. among 152 k. pneumoniae bloodstream isolates suspected as ampc or extended-spectrum β-lactamase (esbl) producers, 58 (38.2%) isolates were currently interpreted as nonsusceptible to ertapenem, imipenem, or meropenem, and 42 (72.4%) of them were categorized as carbapenem-suscept ...201222249422
significance of perioperative infection in survival of patients with ovarian cancer.perioperative infectious diseases comprise some of the most common causes of surgical mortality in women with ovarian cancer. this study was aimed to evaluate the significance of perioperative infections in survival of patients with ovarian cancer.201222228425
different potency of bacterial antigens, both tlr2 and tlr4 ligands, in stimulating mature mast cells to cysteinyl leukotriene synthesis.the aim of study was to compare the potency of different bacterial antigens to induce rat mature mast cell to cysteinyl leukotriene (cyslt) generation. we examined toll-like receptor (tlr)2 agonists, i.e. lipoteichoic acid (lta) staphylococcus faecalis, streptococcus pyogenes, bacillus subtilis and staphylococcus aureus, lipoarabinomannan (lam) mycobacterium smegmatis, peptydoglican (pgn) staphylococcus aureus, as well as tlr4 agonists, i.e. lipopolysaccharide (lps) klebsiella pneumoniae, pseudo ...201222233438
piperacillin-tazobactam as an initial empirical therapy of bacteremia caused by extended-spectrum β-lactamase-producing escherichia coli and klebsiella pneumoniae. 201222274414
development of an optimized random amplified polymorphic dna protocol for fingerprinting of klebsiella pneumoniae.aims:  to develop an optimized random amplified polymorphic dna (rapd) protocol for fingerprinting clinical isolates of klebsiella pneumoniae. methods and results:  employing factorial design of experiments, repeatable amplification patterns were obtained for 54 nosocomial isolates using 1 μmol 1(-1) primer, 4 mmol 1(-1) mgcl(2) , 0·4 mmol 1(-1) dntps, 2·5 u taq dna polymerase and 90 ng dna template in a total volume of 25 μl. the optimum thermocycling program was: initial denaturation at 94° ...201222220979
mitochondrial dna 8993t>g mutation in a child with ornithine transcarbamylase deficiency and leigh syndrome: an unexpected association.mc, female, is the third child of a nonconsanguineous portuguese couple, born after an uneventful pregnancy and delivery. a positive family history of ornithine transcarbamylase deficiency, associated with the ivs8+1 g>a mutation in the ornithine transcarbamylase gene, prompted prenatal diagnosis with identification of the same mutation in the proband. during an episode of klebsiella pneumoniae sepsis at 1.5 months of age, lactic acidosis and moderate hyperammonemia were noticed. after a short a ...201222241703
role of primary bacterial contamination of a pulmonary homograft for ross operation: report of a case and review of the literature.in a 43-year-old female, ross operation was performed with annular reinforcement of the autograft and a cryo-fixed homograft that proved to be contaminated with enterobacter cloacae and klebsiella pneumoniae at the time of operation. clinical course was unremarkable, perhaps due to effective antibiotic prophylaxis and treatment. in the literature, little is known about intraoperative bacterial contamination and early endocarditis. the authors report what they believe is the second reported case. ...201222215504
faecal carriage of extended-spectrum β-lactamase-producing enterobacteriaceae among humans in java, indonesia, in 2001-2002.objective  to characterise commensal escherichia coli and other enterobacteriaceae with reduced susceptibility to cefotaxime that were collected in a large survey carried out among 3995 patients and healthy persons in two urban regions on java, indonesia, in 2001-2002. methods  the putative extended-spectrum β-lactamase (esbl)-producing enterobacteriaceae were analysed using double-disk synergy tests, isoelectric focusing, pcr assays, dna sequencing, and pulsed-field gel electrophoresis (pfge). ...201222248076
prevalence of plasmid mediated bla(tem-1) and bla(ctx-m-15) type extended spectrum beta-lactamases in patients with sepsis.to characterize the bacterial pathogens in patients having gram negative septicaemia. further, to evaluate the antimicrobial resistance and underlying molecular mechanisms in these strains.201222221749
seroepidemiology of klebsiella pneumoniae colonizing the intestinal tract of healthy chinese and overseas chinese adults in asian countries.abstract: background: capsular serotypes k1 and k2 of klebsiella pneumoniae are thought to the major virulence determinants responsible for liver abscess. the intestine is one of the major reservoirs of k. pneumoniae, and epidemiological studies have suggested that the majority of k. pneumoniae infections are preceded by colonization of the gastrointestinal tract. the possibility of fecal-oral transmission in liver abscess has been raised on the basis of molecular typing of isolates. data on th ...201222260182
characterization of a novel klebsiella pneumoniae sequence type 476 carrying both bla (kpc-2) and bla (imp-4).carbapenemase-producing klebsiella pneumoniae has recently spread rapidly throughout china. in this study, we characterized a carbapenem-resistant k. pneumoniae isolate that produced both kpc-2 and imp-4 type carbapenemases. a clinical isolate of k. pneumoniae, resistant to both meropenem and imipenem, was recovered from a urine sample. antibiotic susceptibility was determined using the broth microdilution method and etest (biomérieux, france). pulsed-field gel electrophoresis and multilocus seq ...201222271301
bla (kpc) and rmtb on a single plasmid in enterobacter amnigenus and klebsiella pneumoniae isolates from the same patient.enterobacter amnigenus (ea76) and klebsiella pneumoniae (kp76) isolates with multidrug-resistant (mdr) patterns were identified from the same patient in the neurosurgery department of our hospital. an outbreak of mdr k. pneumoniae had also occurred in this department. to characterize the resistance mechanism and molecular epidemiology of these isolates, sequential experiments including antimicrobial susceptibility testing, polymerase chain reaction (pcr), plasmid analysis, pulsed field gel elect ...201222237458
chemometric modeling and two-dimensional fluorescence analysis of bioprocess with a new strain of klebsiella pneumoniae to convert residual glycerol into 1,3-propanediol.the goal of this study was to show that the metabolism of klebsiella pneumoniae under different aeration strategies could be monitored and predicted by the application of chemometric models and fluorescence spectroscopy. multi-wavelength fluorescence was applied to the on-line monitoring of process parameters for k. pneumoniae cultivations. differences observed in spectra collected under aerobiosis and anaerobiosis can be explained by the different metabolic states of the ce ...201222252443
emergence of klebsiella pneumoniae isolate co-producing ndm-1 with kpc-2 from india. 201221990048
identification of bacterial microflora in the midgut of the larvae and adult of wild caught anopheles stephensi: a step toward finding suitable paratransgenesis candidates.to describe the midgut microbial diversity and to find the candidate bacteria for the genetic manipulation for the generation of paratransgenic anopheline mosquitoes refractory to transmission of malaria, the microbiota of wild larvae and adult anopheles stephensi mosquito midgut from southern iran was studied using a conventional cell-free culture technique and analysis of a 16s ribosomal rna (rrna) gene sequence library. forty species in 12 genera including seven gram-negative myroides, chryse ...201222074685
a randomized, double-blind, placebo-controlled trial of selective digestive decontamination using oral gentamicin and oral polymyxin e for eradication of carbapenem-resistant klebsiella pneumoniae carriage.to assess the effectiveness of selective digestive decontamination (sdd) for eradicating carbapenem-resistant klebsiella pneumoniae (crkp) oropharyngeal and gastrointestinal carriage.201222173517
Exploring the DNA binding mode of transition metal based biologically active compounds.Few novel 4-aminoantipyrine derived Schiff bases and their metal complexes were synthesized and characterized. Their structural features and other properties were deduced from the elemental analysis, magnetic susceptibility and molar conductivity as well as from mass, IR, UV-vis, (1)H NMR and EPR spectral studies. The binding of the complexes with CT-DNA was analyzed by electronic absorption spectroscopy, viscosity measurement, and cyclic voltammetry. The interaction of the metal complexes with ...201222020164
[Five years following of infections with extended-spectrum beta-lactamase producing enterobacteriaceae].Actually, epidemiology of extended-spectrum ß-lactamase (ESBL) producing enterobacteriaceae is increasing worldwide, especially in urinary tract infections (UTI). The objective of the study was to investigate the epidemiology of ESBL producers in a department of urology.201222196001
In vitro activity of avibactam (NXL104) in combination with ß-lactams against Gram-negative bacteria, including OXA-48 ß-lactamase-producing Klebsiella pneumoniae.The objective of this study was to investigate the in vitro antibacterial activity of avibactam (formerly NXL104) in combination with imipenem, cefepime or ceftazidime against Gram-negative bacteria. Bacterial isolates included: Pseudomonas aeruginosa harbouring PER-1 ß-lactamase (n=14); Acinetobacter baumannii harbouring PER-1, OXA-51 and OXA-58 (n=20); carbapenem-non-susceptible Klebsiella pneumoniae (n=25) and Escherichia coli (n=1) harbouring OXA-48; carbapenem-non-susceptible E. coli (n=1) ...201222041508
Refresh
firstprev
...231232233
nextlast
Displaying items 23201 - 23254 of 23254