Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [use of data on shigella contamination and immunity indices for studying the activity of the epidemic process in dysentery]. | the comparative study of the monthly distribution of characteristics indicating the levels of contamination with sh. sonnei and sh. flexneri separately, as well as the seasonal dynamics of the corresponding antibodies, in the years with high and low morbidity levels has been made with the use the indirect hemagglutination test. the possibility of using these characteristics for the evaluation of the activity of the epidemic process in dysentery caused by sh. sonnei is shown. | 1980 | 6449816 |
| artificial carbohydrate antigens: synthesis of rhamnose trisaccharide and disaccharide haptens common to shigella flexneri o-antigens. | 1980 | 6987247 | |
| artificial carbohydrate antigens: the synthesis of a tetrasaccharide hapten, a shigella flexneri o-antigen repeating unit. | the 8-methoxycarbonyloctyl glycoside of the tetrasaccharide hapten, o-alpha-l-rhamnopyranosyl-(1 leads to 2)-o-alpha-l-rhamnopyranosyl-(1 leads to 3)-o-alpha-l-rhamnopyranosyl-(1 leads to 3)-2-acetamido-2-deoxy-beta-d-glucopyranoside and the trisaccharide glycoside 8-methoxycarbonyloctyl o-alpha-l-rhamnopyranosyl-(1 leads to 3)-o-alpha-l-rhamnopyranosyl-(1 leads to 3)-2-acetamido-2-deoxy-beta-d-glucopyranoside were synthesized by sequential koenigs-knorr reactions from monosaccharide units. the ... | 1980 | 6988076 |
| corneal ulceration due to shigella flexneri. | shigella keratitis with ulceration is a rare occurrence with only four previous reports in the literature. corneal ulceration appears to be characteristically superficial with a predilection for the inferior cornea. in the case reported here, resolution of ulceration occurred with the use of gentamicin and chloramphenicol, following a poor response to sulfacetamide. experimental evidence strongly suggests that the course of infection is usually self-limited but that corneal scarring is a common ... | 1980 | 6988565 |
| [state of immunogenesis in different methods of treating acute dysentery]. | 1980 | 6988643 | |
| [sensitivity to antibacterial preparations of the causative agents of intestinal infections in transcarpathia. ii. shigella and enteropathogenic escherichia]. | 1980 | 6988685 | |
| effect of shigella flexneri endotoxin on ureagenesis and liver ultrastructure in rabbits. | 1980 | 6991279 | |
| clinicopathological conference: eleven month old child with bloody diarrhea. | 1980 | 6994225 | |
| [therapeutic effectiveness of nevigramon in the complex treatment of acute dysentery]. | 1980 | 6994350 | |
| cross-reactivity of major outer membrane proteins of enterobacteriaceae, studied by crossed immunoelectrophoresis. | outer membrane fractions were prepared from 11 bacteria in the family enterobacteriaceae: escherichia coli serotypes o1k-, o4k2, o26k60, o75k-, and o111k58, shigella flexneri, salmonella typhimurium, klebsiella pneumonia, serratia marcescens, proteus vulgaris, proteus mirabilis, and providencia stuartii. all strains studied were found to contain one non-peptidoglycan-bound, heat-modifiable outer membrane protein, and one or two peptidoglycan-associated major outer membrane proteins in the 27,000 ... | 1980 | 6995435 |
| resistogram typing of shigella flexneri. | fifty strains of shigella flexneri from sporadic cases of bacillary dysentery were tested for their resistance to 7 antibacterial compounds. sixteen combinations or results were obtained and these were used to form resistograms for the bacteria. the results agreed well with those of serotyping. | 1980 | 6996117 |
| [multiplication dynamics in a pulmonary model of sh. sonnei and sh. flexneri differing in virulence]. | the most essential differences in the time course proliferation of virulent and a virulent sh. sonnei and sh. flexneri strains in the pulmonary model were found to become, manifest 3--6--9 hours postinoculation. in contrast to the avirulent sh. flexneri strains smooth type, with its intensive elimination, the avirulent sh. sonnei strains in phase i were preserved on their primary infective level during these hours, and their subsequent elimination was slower. the differences thus revealed seem t ... | 1980 | 6996394 |
| reiter's syndrome in a five-year-old girl. | 1980 | 6996691 | |
| a new nitrogen base 5-hydroxycytosine in phage n-17 dna. | 1980 | 6997086 | |
| [formation of iron-binding metabolites by bacteria of the enterobacteriaceae family]. | the capacity of enterobacteriaceae strains cultivated in a synthetic medium for the biosynthesis of catechols and hydroxamates has been studied. among the strains under study all strains of the genera salmonella (8 strains), escherichia (102 strains), citrobacter (5 strains), enterobacter (2 strains), serratia (1 strain) synthesize catechols. in the genus shigella (128 strains) all sh. flexneri serovars (79 strains) do not synthesize catechols, other representatives of this genus synthesize iron ... | 1980 | 6998212 |
| [dissemination of bdellovibrio acteriovorus in animals and their interaction with the agents of acute intestinal infections]. | cows, horses, pigs and ducks have been found to contain bdellovibrio bacteriovorus in their intestine and to constantly excrete them with feces into the environment. these microorganisms have not been detected in the feces of man, white mice, frogs and fish. bdellovibrio, if introduced together with shigella or after them, prevent the development of keratoconjunctivitis in some of the rabbits. no manifestations of the lytic activity of bdellovibrio in relation to salmonella and vibrio cholerae h ... | 1980 | 6998228 |
| [live vaccines for the prevention of intestinal infections]. | shigella live vaccine was applied orally, four or five times, to 12000 children, aged between one and seven years. morbidity in the immunised group was 3.5 times as high (9.3 times after boostering) as that in the non-immunised control group. immunity could be provided for four months, and it was strictly specific of types. results so far obtained from animal experiments, such as pulmonary and kerato-conjunctival tests on mice, are likely to support the idea of developing a combination vaccine f ... | 1980 | 6998403 |
| [local immune response in rabbits following enteral immunization with live attenuated bacterial enterobacteriaceae vaccines]. | streptomycin-dependent and inactivated shigella flexneri 2a and shigella sonnei strains were intra-intestinally applied to rabbits for immunisation. rosette and plaque tests and well as indirect haemagglutination gave short-time secretion of low titres of specific copro-antibody, following monovaccines and bivaccines. high titres of secretory antibody were induced, depending on doses, by re-immunisation. no antigen competition was established. the localised immune response caused by shigella liv ... | 1980 | 6998404 |
| detection of r plasmids with a restrictive effect on phage-bacteria shigella flexneri and shigella sonnei systems. | 1980 | 6998412 | |
| randomized trial of high- and low-dose ampicillin therapy for treatment of severe dysentery due to shigella dysenteriae type 1. | to establish optimal therapy for severe dysentery due to shigella dysenteriae type 1 and shigella flexneri, we compared in a prospective randomized trial two oral ampicillin doses (50 and 150 mg/kg per day) in 57 children and 39 adults in dacca, bangladesh. clinical failure did not occur in either group, indicating that conventional doses need not be increased even in severe disease. among children 3 years of age or under, bacteriological relapses tended to be more frequent in the low-dose group ... | 1980 | 6999981 |
| possible role of colonic content in the mucosal association of pathogenic shigella. | association of shigella flexneri to cecal membrances was studied by incubating the pathogen with cecal slices of germfree mice. the slices were first incubated with stool supernatants from germfree, shigella-monocontaminated, and conventional animals. quantitation of shigellae in homogenates of treated slices revealed an increase of organisms only in those slices exposed to contaminated stool supernatants. | 1980 | 7000704 |
| antibody-dependent cell-mediated antibacterial activity: k lymphocytes, monocytes, and granulocytes are effective against shigella. | normal human peripheral blood lymphocytes, monocytes, and granulocytes decreased the viability of shigella flexneri in vitro in cooperation with heat-inactivated rabbit hyperimmune anti-shigella antisera. purified k and t lymphocyte populations used before the removal of fc receptor-bearing cells were effective in this antibody-dependent complement-free system. in contrast, b lymphocytes and t lymphocytes from which fc receptor-bearing cells were removed exhibited no activity. in the absence of ... | 1980 | 7000906 |
| isolation and characterization of minicell-producing mutants of shigella spp. | minicells are small, anucleate cells resulting from aberrant cell divisions at the polar ends of bacilli. we have isolated minicell-producing mutant strains of shigella flexneri 2a (mc-i) and shigella dysenteriae 1 (mc-v) after mutagenesis with n-methyl-n'-nitro-n-nitrosoguanidine. microscopically, broth cultures of mc-i and mc-v were found to contain free minicells, normal cells, and filamentous cells with polar, attached minicells. both strains retained their ability to provoke keratoconjuncti ... | 1980 | 7002790 |
| protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of shigella spp. | active immunization of guinea pigs and rabbits with outer membrane proteins (omp) isolated from shigella flexneri 3a and shigella sonnei phase i protected the animals against keratoconjunctivitis shigellosa induced with the homologous or heterologous strain. protection was also achieved in rabbits after passive immunization with anti-omp immune serum. active immunization with lipopolysaccharide of s. flexneri 3a did not protect rabbits against keratoconjunctivitis shigellosa. | 1980 | 7002794 |
| contrasting epidemiology of shigellae dysenteriae and shigellae flexneri, dacca. | 1980 | 7003832 | |
| [etiological structure of dysentery in the verkhnebureya district, khabarovsk territory, in 1974-1976]. | 1980 | 7004000 | |
| [enteric dysentery vaccines and their effectiveness in a rabbit intestinal loop model. i. the residual virulence of attenuated vaccinal strains of shigella administered into the intestinal loops]. | virulent sh. flexneri strain 2a, sh. sonnei strain, attenuated sh. flexneri vaccine strain 2a 516m, and sh. sonnei vaccine strain 6s (isolated by yu. a. belaya), as well as streptomycin-dependent sh. flexneri strain 2a 1605/3 (isolated by v. v. sergeev) were introduced into the ligated loops of the rabbit ileum. the use of light and immunofluorescent microscopy, the measurement of the volume of the fluid in the intestinal loops and the quantitative inoculation of their contents resulted in revea ... | 1980 | 7004003 |
| [shigella flexneri mutation giving rise to the appearance of fosfomycin-resistant avirulent forms with disordered carbohydrate utilization]. | the present work analyzes pt44 mutation in sh. flexneri resulting in the appearance of the following phenotypical properties: resistance to phosphomycin, avirulence, pleiotropic disturbances in carbohydrate utilization. the data provided by the biochemical and genetic analysis have indicated that pts44 mutation occupies the region between purc and ptsi loci on the chromosome of sh. flexneri. merodiploids containing the mutant allele pts44 and the plasmid including purc-ptsi-ptsh genes from e. co ... | 1980 | 7004011 |
| [certain features of the boivin antigens of streptomycin-dependent sh. flexneri 2a strains differing in immunogenicity]. | 1980 | 7004013 | |
| [characteristics of attenuated immunogenic mutants of shigella flexneri selected from phosphomycin-resistant clones]. | sh. flexneri mutants no. 2a, resistant to phosphomycin (25 microgram/ml), differ in their fermentability in respect to glucose, mannitol, mannose and fructose. the mutants fall into 7 groups by this characteristic. all the resistant mutants, irrespective of the type of hydrocarbon fermentation, have lost their ability of causing keratoconjunctivitis. the decreased virulence of the phosphomycin-resistant mutants is linked with the loss of their penetration properties, although their adhesiveness ... | 1980 | 7004017 |
| [chromosomal transformation of escherichia coli by shigella flexneri dna]. | 1980 | 7004023 | |
| effects of endotoxin from different bacteria on ovum transport in rabbits. | 1980 | 7004496 | |
| yersinia pseudotuberculosis infection in a group of macaca fascicularis. | diarrheal disease associated with abortions and stillbirths occurred in a group of 42 macaca fascicularis. the group was composed of wild-caught adults and their colony-born offspring housed in a half-acre cage. thirteen adult females and 1 infant male were affected. all 14 monkeys had diarrhea and all 9 pregnant females either aborted or had a stillbirth. yersinia pseudotuberculosis was isolated from 7 animals. in addition, y enterocolitica was isolated from 1 monkey and shigella flexneri type ... | 1980 | 7005202 |
| faecal excretion of entero-pathogens in a pakistani family returning to the u.k. after a visit to rawalpindi. | the family consisted of two parents and five children. while the father remained in cardiff, the mother and all the children visited rawalpindi, pakistan, for 6 weeks to stay with relatives. travel was by flight from heathrow airport to pakistan and by a short road journey to rawalpindi. mrs m. - the mother - as a guest, did no cooking on the holiday. the house which they were living in had a piped water supply, thought to be treated. there was no flush toilet but a commode was available and was ... | 1980 | 7005329 |
| [serum creatine phosphokinase, got, and gpt activity in different types of infectious diseases in monkeys]. | an increase in creatine phosphokinase (cpk) activity as well as a decrease in activities of aspartate aminotransferase (aat) and alanine aminotransferase (alt) were observed in monkey blood serum under conditions of experimental infection of the animals with dysentery. contrary to the non-immunized animals, the activity of cpk was increased but the activities of aat and alt were unaltered in blood serum of the immunized monkeys. estimation of the enzymatic activity might be used for diagnosis of ... | 1980 | 7006207 |
| survival of shigellae in soil. | the survival of four shigella strains in soil (sh. sonnei, sh. boydii, sh. flexneri and sh. dysenteriae) was studied under various conditions. their survival period was tested in two different types of sterile soil at 18-20 degrees c and in one type of soil at 4 and 37 degrees c. this latter type of soil, after enrichment with casaminoacids or (nh4)2hpo4 was also used for testing again the survival of the strains at 18-20 degrees c. though the initial number of the inoculated microorganisms was ... | 1980 | 7006270 |
| endotoxin-induced uveitis in the rat. | experimental studies of ocular inflammation induced by endotoxin have been performed almost exclusively in rabbits. although the rat has been considered refractory to both the systemic and local effects of endotoxin, the present study has shown that intravitreal injection of endotoxin evoked a characteristic acute inflammatory response which was reproducible and dose-dependent. in addition, a consensual ocular response in the control eye occurred which was less severe but also dose-dependent. pr ... | 1980 | 7006439 |
| resistance to trimethoprim and other antibiotics in shigellae isolated in the province of ontario. | antimicrobial susceptibility determinations for three commonly used and seven seldom used antibacterial drugs against 482 strains of shigellae isolated in ontario during 1977 and 1978 were carried out. resistance to the first-line treatment drugs, ampicillin and tetracycline, occurred in 20.5 and 39.2% of strains, respectively. the emergence of trimethoprim-sulfamethoxazole resistance was noted for the first time in 3.2% of the strains in 1978. all strains retained their susceptibility to gentam ... | 1980 | 7006767 |
| structural studies on shigella flexneri serotype 6 core region. | the core structure of shigella flexneri serotype 6 has been investigated. the methods used in these studies involved methylation analysis, periodate oxidation, smith degradation and enzymic modifications of core oligosaccharides isolated from two smooth strains and four rough mutants. as a result the complete core region was established (formula: see text) where dgalp = d-galactopyranose, dglcp = d-glucopyranose, l alpha dhepp = l-glycero-d-mannoheptapyranose, docla = 3-deoxy-d-manno-octulosonic ... | 1980 | 7007048 |
| [effect of antibacterial therapy on regeneration of large-intestinal mucosa in dysentery]. | 1980 | 7008234 | |
| monocyte function in rheumatoid arthritis. | monocytes derived from peripheral blood of patients with rheumatoid arthritis (ra) had a marked defect in their bactericidal activity against staphylococcus albus and listeria monocytogenes; whereas the phagocytic capacity of monocytes from ra patients for both staph. albus and shigella flexneri was similar to that of monocytes from healthy subjects. there were no significant differences between the patient and control groups with regard to antibody dependent cellular cytotoxicity (adcc) of mono ... | 1980 | 6769149 |
| [isolation of metal-resistant shigella flexneri and its application to experimental animal infection. 1. isolation of cd and zn resistant strain and its characters (author's transl)]. | 1980 | 6770010 | |
| [isolation of metal resistant shigella flexneri and its application to experimental animal infection. 2. comparison of biochemical and serological characters among the original, the cd, zn resistant and the tc resistant strain (author's transl)]. | 1980 | 6772717 | |
| [features of the infectious process caused by shigellae of different species]. | 1980 | 6778021 | |
| [shigella: microbiological aspects and incidence in our environment]. | 1980 | 6755638 | |
| fatal shigella dysentery complicated by toxic megacolon and bone marrow aplasia in a patient with chronic granulocytic leukemia in remission. | a patient with philadelphia positive chronic granulocytic leukemia in clinical remission is described, who developed shigella dysentery complicated by fatal toxic megacolon, pancytopenia and bone marrow aplasia. the difficulties of differential diagnosis between active ulcerative colitis and shigella dysentery and problems relating to the management of these two disorders are discussed. leukocyte function in chronic granulocytic leukemia and its role in infection in these patients is also briefl ... | 1980 | 7009362 |
| shigella septicaemia following renal transplantation. | two patients are described who developed septicaemia with shigella flexneri following renal transplantation. pre-operative screening had not identified either patient as a chronic carrier of shigella sp. the acute management and problems posed by unrecognized carriers amongst patients undergoing transplantation in areas of the world where shigella is endemic, are discussed. | 1980 | 7022421 |
| [mapping of mutations in genes of flexner shigellae controlling the synthesis of certain ribosomal proteins and study of the effect of these mutations on bacterial virulence]. | the study, carried out to localize the mutations which determine resistance to spectinomycin and neamin, has revealed that in sh. flexneri the genes of the str -- s area and located in the order similar to the order of their location in e. coli k12: spc a -- nea a -- str a -- nea b. mutation in spc a gene was shown to have no influence on the capacity of the shigellae for causing keratoconjunctivitis, whereas nea a mutation resulted in the complete loss of virulence; in str a and nea b mutations ... | 1980 | 7013375 |
| a study on experimental keratoconjunctivitis shigellosa. | 1980 | 7035740 | |
| bacteriological and epidemiological approaches to the prophylaxis of enteric infection. vi. in vitro studies on the mechanism of acquired resistance to shigella flexneri infection (1). | 1980 | 7035741 | |
| [shigella interaction with immune enterocytes]. | the immunity induced in rabbits by oral immunization with boivin shigella polyantigen results in activation of enterocytes: hypertrophy and dilatation of the golgi apparatus and endoplasmic reticulum, increase in the number of sizes of primary and secondary lysosomes. resistance of the immune enterocytes to shigella is manifested in a decreased number of bacteria able to penetrate the cytoplasm, the absence of lysis of heterophagosome membrane surrounding the organisms, and the lack of fusion of ... | 1980 | 7011272 |
| shigellosis in the marshall islands: epidemiologic aspects of an outbreak. | an outbreak of diarrheal illness caused by shigella flexneri 1b and associated with 11 deaths occurred in the marshall islands during june and july 1977. a house-to-house survey on majuro indicated an attack rate of 6.2%. neither the survey nor a case-control study uncovered a common source of exposure on majuro, and it is believed that transmission was mainly person-to-person. socioeconomic factors, type of water supply, distance to municipal water supply, and type of sanitary facility could no ... | 1980 | 7386724 |
| [antibiotic resistance of shigella strains isolated in cádiz (author's transl)]. | the incidence of shigellosis at the residencia sanitaria fernando zamacola (cáciz, spain) and the antibiotic sensitivity of 94 strains of shigella sonnei and 40 strains of shigella flexneri, isolated during the year 1979, has been studied taking into account the present status of strain resistance to the major antibiotics. three epidemic bouts of shigellosis were detected: one in february by shigella sonnei (16 cases), and two others in august-september and november due to shigella flexneri (43 ... | 1980 | 7464328 |
| salmonella typhi r-plasmids in hungary. | the antibiotic sensitivity of 4095 salmonella typhi strains isolated in hungary from january, 1974 to june 1979, was tested. twelve strains derived from one patient and seven chronic carriers were resistant to antibiotics due to r-plasmids. one of the s. typhi strains carried two r-plasmids and the change in the phage type of this strain was caused by one of the plasmids. r-plasmid of the same restrictive property was found in an escherichia coli strain isolated from the faeces of the correspond ... | 1980 | 7468321 |
| high frequency of hla-b27 and reiter's syndrome in navajo indians. | eighteen cases of reiter's syndrome were found in a population of approximately 6,000 navajo indians. the phenotype frequency of hla-b27 in this population was found to be 36%. the area in which these people live is endemic for shigellosis, shigella flexneri being the most common species isolated. presumably the high frequency of hla-b27 and shigella infections account for the high incidence and prevalence of reiter's syndrome in this population. | 1980 | 7205829 |
| liposomes as vehicles for vaccines. | lipid a from shigella flexneri lps, or acylated derivatives of muramyl dipeptide (mdp), were incorporated into the lipid bilayer of liposomes to enhance the adjuvanticity of the liposomes in rabbits. liposomes containing lipid a induced antibodies against lipid a, phosphocholine, phosphatidylcholine, and sphingomyelin. lipid a was resolved into eight fractions, some of which did, and others of which did not, induce antibodies against liposomes. anti-liposome antibodies also were induced (in the ... | 1980 | 7208512 |
| proliferation of enteropathogens in oral rehydration solutions prepared with river water from honduras and surinam. | oral rehydration of infants with diarrhoea is an effective therapy that is becoming increasingly available in developing countries. to formulate judicious recommendations for preparation and storage of such solutions, we assessed the capability of recognized bacterial enteropathogens to survive and proliferate in solutions made either with sterile distilled or river water collected in two developing countries. shigella flexneri, an enteropathogen typically transmitted by faecal/oral contact rath ... | 1981 | 7299876 |
| protein synthesis in hela or henle 407 cells infected with shigella dysenteriae 1, shigella flexneri 2a, or salmonella typhimurium w118. | the incorporation of [14c]leucine into protein was studied in two mammalian cell lines which had been infected with strains of shigella dysenteriae 1, shigella flexneri 2a, or salmonella typhimurium w118. these cell lines differed in susceptibility to the effects of exogenously applied shiga cytotoxin. all invasive shigella strains (which synthesize this toxin to a greater or lesser degree) were found to inhibit protein synthesis in both cell lines with equal efficiency. leucine accumulation con ... | 1981 | 7012026 |
| oxygen as a product of water radiolysis in high-let tracks. ii. radiobiological implications. | 1981 | 7012902 | |
| [participation of cyclic nucleotides, ca ions and gastrin in the pathogenesis of the diarrheal syndrome in acute dysentery]. | 1981 | 7038902 | |
| [etiological factors in bacillary dysentery in poland 1965-1979]. | 1981 | 7041196 | |
| [shigellosis in pediatric wards]. | 1981 | 7042492 | |
| [properties of shigellae relevant to food hygiene]. | 1981 | 7044337 | |
| towards serodiagnosis of serratia marcescens infections: examination of sera from noninfected patients and from experimentally infected rabbits for anti-h and anti-o antibodies; s. marcescens o-antigen cross-reactions with those of other enterobacteriaceae. | sera from 100 patients not infected with serratia marcescens at the time of hospital admission lacked detectable h-immobilizing antibodies against all 20 currently recognized h-antigens of this microorganism. however, various patient sera revealed elevated titers of o-agglutinins against several of the 20 o-antigens of s. marcescens, in a particular o-antigens, o1, o3, o4, o5, o7, o8, o10, o11, o16, o17, o18, o19, and o20. rabbit anti-shigella serogroup b immune serum cross-reacted with s. marce ... | 1981 | 7036590 |
| [an oral enteritis-vaccine composed of twelve heat-inactivated enterobacteriaceae 3. communication: studies on efficacy tests in mice protection tests (author's transl)]. | the polyvalent vaccine consists of twelve heat-inactivated species of enterobacteriaceae (six strains of salmonellae, two strains of shigellae, four strains of dyspepsia coli). the above vaccine is administered orally (6) to man for prophylactic purposes against local infections. the present communication describes the efficacy results of the vaccine obtained for different parameters by the mouse protection test. for this purpose, seven different infection models were used: oral infection with a ... | 1981 | 7036591 |
| seroepidemiological studies with campylobacter fetus. | 324 sera from unselected male and 581 sera from female patients as well as 268 sera from prostitutes were studied for antibodies against campylobacter fetus using the complement fixation test. antigen was campylobacter fetus subspecies intestinalis. 3.9% of the sera showed low but relevant antibody titers. statistically significant differences don't exist between the three population investigated. serological cross reactions could not be observed using salmonella typhimurium, shigella flexneri, ... | 1981 | 7036594 |
| [use of live flexner 2a 516m dysentery vaccine for the immunotherapy of acute and chronic dysentery]. | live dysentery vaccine prepared from sh. flexneri 2a 516 m, a spontaneous mutant, was used for the treatment of 153 patients with acute and chronic dysentery. a single oral administration in a dose of 25 x 10(9) live microbial cells and 2 oral administrations in doses of 25 x 10(9) and 50 x 10(9) live microbial cells did not induce the clinical aggravation of the disease, greatly reduced the time of the reparation of the intestinal mucosa and reduced the frequency and duration of excretion of th ... | 1981 | 7036601 |
| [separation of shigella toxins into fractions differing in biological activity and characteristics of the fractions inducing penetration in avirulent strains]. | the results obtained in the study of the biological activity of the lysates of 14 sh. flexneri and sh. sonnei strains differing in their virulence are presented. in the lysates of the virulent cultures 2 kinds of biological activity corresponding to the fractions of peaks i and ii could be detected: one fraction possessed hela toxicity, the other fraction possessed enterotoxic activity. the avirulent nonpenetrating mutants had no hela toxicity, but retained their capacity for producing factors s ... | 1981 | 7034411 |
| [antigenic characteristics of a preparation obtained by a non-destructive method from shigella flexneri and shigella sonnei]. | 1981 | 7034415 | |
| [liver and kidney function after immunization with an enteral vaccine from shigella flexneri and shigella sonnei antigens (blood biochemical test data)]. | 1981 | 7034416 | |
| [physicochemical characteristics of transfer derepressed pkmr plasmids]. | a group of transfer derepressed r factors (pkmr plasmids) was identified with the methods of conjugation and transformation in 2 antibiotic resistant strains of the dysentery bacillus, i. e. shigella flexneri 3c and sh. sonnei isolated from patients with acute dysentery. the antibiotic resistance in s. flexneri was controlled by plasmid pkmr 202-2 (sm tc cm km su) with a molecular weight of 59 md and that in sh. sonnei was controlled by 2 plasmids, i. e. pkmr 203-2 (ap sm tc cm km su) and pkmr 2 ... | 1981 | 7034638 |
| role of antigen form in development of mucosal immunoglobin a response to shigella flexneri antigens. | one major stumbling block in the development of an effective means to immunize against shigellosis and other enteric diseases has been the lack of a means to assess sequential mucosal immune responses to different potential immunogens. in the present study, we compared the abilities of live invasive organisms, noninvasive organisms, and nonviable antigen preparations of shigella to elicit mucosal immune responses. whereas previous studies have found that effective immunity was produced best by v ... | 1981 | 7014458 |
| [effect of the products of the viral activities of shigellae on the physicochemical properties of blood plasma proteins in experimental animals]. | 1981 | 7015080 | |
| [severity of the clinical manifestations of sonnei an flexner dysentery]. | 1981 | 7015757 | |
| [study of enteric dysentery vaccines and their efficacy on a rabbit intestinal loop model. ii. changes in the mucosa of rabbit small intestine after oral immunization with live and chemical vaccines]. | ten days after oral immunization of 3 groups of rabbits with live vaccine prepared from the mixture of streptomycin-dependent mutants of sh. flexneri 2a and sh. sonnei, with sh. flexneri and sh. sonnei tryptic lysate, or with boivin's extract of 6 sh. flexneri and sh. sonnei serotypes, a pronounced activation of the secretory and lysosomal apparatus was observed in ileac enterocytes. deteriorating bacteria or their antigenic material was observed in ileac enterocytes. deteriorating bacteria of t ... | 1981 | 7015764 |
| pattern of shigella flexneri serotypes and drug-resistance in dacca. | 1981 | 7016755 | |
| shigella and shigellaemia. | two cases of bacteraemia with shigella flexneri 2a in children are described. they illustrate the wide variety of clinical manifestations of shigellosis, ranging from benign gastroenteritis to septicaemia associated with severe extra-intestinal manifestations. | 1981 | 7017908 |
| [obtaining shigella flexneri 2a mutants defective in utilization of certain carbon sources, their genetic and biological characteristics]. | various methods, including selection by resistance to the antibiotic mecillinam have been used to obtain sh. flexneri mutants capable of utilizing mannitol and mannose as the sources of carbon. the mutation which determines this phenotype is localized in str-spc area and cotransduced with str a gene (28-33%). the appearance of this mutation in the initial sh. flexneri strain 516 led to a decrease in the virulence of this strain for guinea-pigs. the restoration of its properties and the partial r ... | 1981 | 7018130 |
| [etiologic structure of dysentery in cheliabinsk and its relation to the morbidity level and bacteriologic confirmation]. | 1981 | 7018138 | |
| [radiologic examination in shigellosis (author's transl)]. | 1981 | 7018357 | |
| salmonella and shigella surveillance in hungary, 1972-1976. ii. shigella surveillance. | shigellae were isolated from 32 399 persons in the bacteriological laboratories of the public health stations between 1972-1976. the number of isolations ranged between 5325 and 8237 yearly. as s. dysenteriae and s. boydii serotypes occurred only in about 1.5% of all isolations, the epidemiological situation was determined by the incidence of s. flexneri and s. sonnei. except in 1973, s. sonnei constituted the majority in every year. s. sonnei predominance, observed first in the western regions ... | 1981 | 7020354 |
| [effect of a pulsatile magnetic field on shigella flexneri]. | 1981 | 7023140 | |
| [oral intestinal vaccines and their effectiveness in the rabbit intestinal loop model. iii. effectiveness of oral immunization with live and chemical vaccines]. | the effectiveness of the oral immunization of rabbits was manifested by a decrease in the number of virulent shigella penetrating enterocytes, by the limited proliferation of bacteria in the epithelium and by the less pronounced ulcerous inflammation of the mucous membrane in the intestinal loops even after infection with large doses (10(9) bacteria). in electron microscopy this was manifested by the destruction of shigella cells in heterophagosomes formed in enterocytes. the degree of fluid acc ... | 1981 | 7023143 |
| [transformation reaction study of e. coli competence]. | 1981 | 7023154 | |
| [role of catalase in shigella flexneri and s. sonnei survivability in phagocytes]. | 1981 | 7024743 | |
| studies on virulence of shigella flexneri. protective effect of outer membrane proteins. | groups of mice were immunized intraperitoneally with proteins isolated from outer membrane of virulent strain of shigella flexneri 3a and its avirulent variant. all the animals were found to survive challenge with ld100 of virulent sh. flexneri 3a. similar protective effect against challenge with sh. flexneri 3a gave also immunization of mice with outer membrane proteins isolated from sh. flexneri of other serotypes (2a, 4a, 6, and x) and from escherichia coli, hafnia alvei and shigella sonnei. | 1981 | 7025793 |
| a chronic carrier of trimethoprim-sulphamethoxazole-resistant shigella flexneri serotype 1. | 1981 | 7026229 | |
| shigellosis in infants and children. | 1981 | 7026439 | |
| [rare case of mixed infection (tick-borne encephalitis, typhoid, dysentery and opisthorchiasis)]. | 1981 | 7026892 | |
| [relation of dysentery drug therapy to the development of antibiotic resistance in shigella]. | 1981 | 7027914 | |
| [group of derepressed pkmr plasmids found in wild strains of shigella]. | a group of derepressed (drd) r plasmids was identified in 3 clinical isolates of shigella, i. e. sh. flexneri 1b, sh. flexneri 3c and sh. sonnei resistant to ampicillin (ap), streptomycin (sm), tetracycline (tc), chloramphenicol (cm), kanamycin (km) and sulfathiazole (su). the plasmids were designated as pkmr 202-2 (sm, tc, cm, km, su), pkmr 203-3 (ap, tc, cm, su), pkmr 204--2 (sm, km, su), pkmr 204-3 (ap, sm, cm, km, su), pkmr 204-4 (ap, sm, km, su), pkmr 204-5 (km, su), pkmr 204-6 (ap, sm, tc, ... | 1981 | 7027918 |
| [radioprotective properties of shigella antigens]. | 1981 | 7029609 | |
| [outcomes of acute dysentery]. | 1981 | 7029905 | |
| [formation of l-forms of shigella flexneri and shigella sonnei in vitro]. | 1981 | 7029982 | |
| endemic enteric disease in vervet monkeys. | comprehensive bacteriological investigation indicates shigellae as the probable aetiological bacteria in one endemic enteric disease situation. one species and four serotypes have been detected. in vitro antibiotic sensitivity spectra have been determined. epidemiology, pathology and pathogenesis in relation to the experimental animal situation and experimental results are considered. a rationale for treatment and control is suggested. | 1981 | 7031245 |
| enhancement of gas production in a strain of shigella flexneri serotype 6 by r plasmids. | the introduction of four different r plasmids into an aerogenic strain of shigella flexneri serotype 6 resulted in changes in the amount of gas produced and in the range of carbohydrates from which this occurred. the possible causes of these changes and their implications for bacterial identification are discussed. | 1981 | 7031253 |
| [mechanism of adhesion of shigella to the intestinal mucosa]. | 1981 | 7032161 | |
| splenic abscess and hepatic dysfunction caused by shigella flexneri. | 1981 | 7009818 | |
| [shigella bacteremia. report of three cases]. | shigella bacteremia is very uncommon, although it is known to occur in shigella infection. three cases of shigella flexneri bacteremia are reported, two of them diagnosed at the residencia ntra. sra. de aránzazu of san sebastián, and another at the ciudad sanitaria francisco franco of barcelona. in spite of the frequency of shigella infections in spain, no cases of shigella bacteriemia had been heretofore reported from our country. one of the patients was an alcoholic woman who died in coma and ... | 1981 | 7010019 |
| reiter's syndrome following epidemic shigellosis. | to define the epidemiology of post-dysenteric reiter's syndrome (rs), 1,162 persons were questioned about compatible symptoms soon after 3 separate outbreaks of shigellosis. we diagnosed rs for 3 women of 204 persons ill during an outbreak of shigella flexneri 1b, for 3 women of 206 ill during an outbreak of s. flexneri 2a, and for none of 85 ill during an outbreak of s. sonnei. we found no rs among 667 persons without diarrhea. prospective controlled investigations in defined populations docume ... | 1981 | 6948959 |