Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| an etiologic approach to management of duodenal and gastric ulcers. | with rare exception, peptic ulcers can now be classified as either helicobacter pylori-related, induced by nonsteroidal anti-inflammatory drugs (nsaids), or related to zollinger-ellison syndrome. helicobacter pylori-related ulcers can be treated by eradication of h pylori or by traditional therapies, including antisecretory drugs or sucralfate. successful eradication of h pylori requires compliance with a multidrug regimen. therefore, candidates should demonstrate substantial motivation. in gene ... | 1994 | 8289053 |
| [helicobacter pylori positivity]. | 1994 | 8295777 | |
| one week's anti-helicobacter pylori treatment for duodenal ulcer. | this open study tested whether eradication of helicobacter pylori (h pylori) heals duodenal ulcers as well as decreasing recurrence. h pylori was detected in patients with endoscopic duodenal ulcers by histology, clo-test, culture, and 13c-urea breath test (13c-ubt). tripotassium dicitrato bismuthate (120 mg) and amoxycillin (500 mg) each four times daily, were given for seven days, with 400 mg metronidazole five times a day on days 5-7. the 13c-ubt was repeated immediately after treatment and e ... | 1994 | 8307442 |
| evidence for the essential role of helicobacter pylori in gastric ulcer disease. | helicobacter pylori (h pylori) eradication heals chronic active type b gastritis and dramatically changes the natural history of duodenal ulcer disease. there are few data concerning the role of anti-h pylori treatment in gastric ulcer disease. a total of 83 patients presenting with h pylori positive active gastric ulcer disease were treated with omeprazole and antibiotics (amoxicillin, ciprofloxacin, roxithromycin) in seven different clinical protocols, each of which included the attempt to era ... | 1994 | 8307443 |
| helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo. | to determine if reactive oxygen metabolites have a pathogenic role in helicobacter pylori (h pylori) related gastroduodenal disease, this study measured their production in antral mucosal biopsy specimens. two related chemiluminescence techniques were used comparing h pylori positive (n = 105) and negative patients (n = 64) with a similar spectrum of macroscopic disease. after chemiluminescence assays, biopsy specimens were graded histologically. increased luminol dependent chemiluminescence (de ... | 1994 | 8307467 |
| helicobacter pylori in dyspeptic children and adults: endoscopic, bacteriologic and histologic correlations. | using different bacteriological (urease test, gram staining and culture) and histological (steiner staining and modified giemsa staining) techniques, we searched for the presence of helicobacter pylori in the gastric antrum of 200 dyspeptic brazilian patients (106 females and 94 males aged 19 days to 81 years). the presence of bacteria was then correlated with the endoscopic and histological findings. h. pylori was present in 59.5% of the population studied. in brazil, colonization occurs early, ... | 1994 | 8524059 |
| one-year follow-up of duodenal ulcers after 1-wk triple therapy for helicobacter pylori. | to study the ulcer recurrence rate of helicobacter pylori-positive duodenal ulcers at 1 yr after eradication of the bacteria by triple therapy. | 1994 | 8304303 |
| helicobacter pylori infection and development of gastric or duodenal ulcer in arthritic patients receiving chronic nsaid therapy. the misoprostol study group. | helicobacter pylori infection and nonsteroidal anti-inflammatory drug use are both common causes of peptic ulcer. it remains unclear whether h. pylori/nsaid interactions occur, and if they do, with what result(s). | 1994 | 8304304 |
| establishment of a small animal model for human helicobacter pylori infection using germ-free mouse. | to understand why oral inoculation of helicobacter pylori resulted in continuous colonization of the stomach in germ-free athymic mice, but only temporary colonization in mice that were not germ-free. | 1994 | 8304305 |
| sulglycotide effect on the proteolytic and lipolytic activities of helicobacter pylori toward gastric mucus. | infection with helicobacter pylori is now recognized as a major factor in the etiology of gastric disease, and among the detrimental effects this bacterium exerts on the mucosal integrity is the elaboration of extracellular protease and lipase enzymes capable of mucus protein and lipids degradation. we present here evidence that the activities of these enzymes are inhibited by an gastroprotective agent, sulglycotide. | 1994 | 8304309 |
| sex ratio of helicobacter pylori infection in childhood. | 1994 | 8304332 | |
| helicobacter pylori gastritis in dyspeptic children. a long-term follow-up after treatment with colloidal bismuth subcitrate and tinidazole. | the connection between dyspeptic symptoms and helicobacter pylori infection was studied prospectively in 21 children treated for verified h. pylori infection with bismuth subcitrate and tinidazole. gastroscopy with biopsy was performed before and a mean of 4 months after discontinuation of the treatment. a second post-treatment check with determination of h. pylori antibodies and serum pepsinogen 1 level was made a mean of 1.5 years after cessation of treatment. the therapy given cleared the bac ... | 1994 | 8209177 |
| helicobacter pylori infection in north-eastern peninsular malaysia. evidence for an unusually low prevalence. | the prevalence of helicobacter pylori infection was determined in peptic ulcer patients, in non-ulcer dyspepsia (nud) patients, and in the general adult population. the h. pylori infection rate ascertained by microbiologic examination of multiple gastric antral biopsy specimens was 50% (17 of 34) in duodenal ulcer (du), 5% (1 of 22) in gastric ulcer, and 9% (15 of 159) in nud patients. a seroepidemiologic survey showed a prevalence of only 4.2% among 496 blood donors and 4.8% among 921 subjects ... | 1994 | 8209178 |
| gastric mucosal injury: microcirculation and helicobacter pylori. | the integrity of gastric mucosa is well-balanced by an array of defensive mechanisms which protect the mucosa against external aggressive factors. when excessive stimulation of autonomic nervous system (irritation) is induced, microcirculatory disturbances easily lead to the gastric mucosal damage due to the formation of vasoactive mediators and oxygen radicals. in this review, our discussion has been focused on the co-ordinating function of the autonomic nervous system as well as the microcircu ... | 1994 | 8189675 |
| ulcers and gastritis. | 1994 | 8205994 | |
| helicobacter pylori infection in infants born from positive mothers. | 1994 | 8273790 | |
| use of high efficacy, lower dose triple therapy to reduce side effects of eradicating helicobacter pylori. | to evaluate two triple-therapy (tt) regimens of colloidal bismuth subcitrate (cbs), metronidazole, and tetracycline hcl in eradicating helicobacter pylori, with particular attention to the frequency of resulting adverse effects of the two therapies. | 1994 | 8273794 |
| medium-term results of oral and intravenous omeprazole/amoxicillin helicobacter pylori eradication therapy. | the aim of the present study was to examine the effect of the application route of the antibiotic amoxicillin in helicobacter pylori eradication, using omeprazole/amoxicillin. | 1994 | 8273795 |
| helicobacter pylori infection as a cause of gastritis, duodenal ulcer, gastric cancer and nonulcer dyspepsia: a systematic overview. | to evaluate current evidence for a causal relation between helicobacter pylori infection and gastritis, duodenal ulcer, gastric cancer and nonulcer dyspepsia. | 1994 | 8287340 |
| indications for treatment of helicobacter pylori infection: a systematic overview. | to determine (a) the advantages and disadvantages of treatment options for the eradication of helicobacter pylori and (b) whether eradication of h. pylori is indicated in patients with duodenal ulcer, nonucler dyspepsia and gastric cancer. | 1994 | 8287341 |
| lymphocytic gastritis: a positive relationship with celiac disease. | lymphocytic gastritis is characterized by lymphocytic infiltration of the surface and pit epithelium. its cause has not been established, but an association with helicobacter pylori infection or celiac disease has been suggested. we evaluated the histologic features of both gastric and duodenal biopsy specimens from 245 consecutive children and adolescents, and found chronic gastritis in 60 children and celiac disease in 25. chronic gastritis was associated with h. pylori infection in 36 childre ... | 1994 | 8283376 |
| effects of cations on helicobacter pylori urease activity, release, and stability. | the urease of helicobacter pylori is an important antigen and appears critical for colonization and virulence. several studies have indicated a superficial localization for the h. pylori urease, and the purpose of this study was to determine the effects of cations on the release and stability of urease activity from h. pylori cells. incubation of partially purified h. pylori urease in water containing 1, 5, or 10 mm ca2+, mg2+, k+, na+, edta, or egta [ethylene glycol-bis(beta-aminoethyl ether)-n ... | 1994 | 8262643 |
| high prevalence of neutralizing activity to helicobacter pylori cytotoxin in serum of gastric-carcinoma patients. | helicobacter pylori infection is causally related to chronic type-b gastritis, and may also be associated with an increased risk of gastric carcinoma. vacuolating cytotoxin, which is an 87-kda protein secreted by h. pylori, induces eukaryotic cell vacuolation in vitro. to determine whether there is an association between h. pylori vacuolating cytotoxin and gastric carcinoma, we investigated several characteristics of h. pylori infection, i.e., isolation of h. pylori from gastric biopsies, antibo ... | 1994 | 8262677 |
| gastric lymphoma in an 11-year-old boy: a case report. | a child with prolonged abdominal symptoms was shown to have a concomitant gastric non-hodgkin lymphoma and gastritis caused by helicobacter pylori infection. after a course of antibiotics and 6 months of chemotherapy, the patient is disease free. the relationship of the microbial infection and tumor development is discussed. the case supports a hypothesis that local h. pylori infection may be a predisposing factor for gastric lymphoma. | 1994 | 8232084 |
| possible role of helicobacter pylori infection in early gastric cancer development. | gastric cancer is the most frequently diagnosed malignancy in japan. the possible relationship between helicobacter pylori infection and gastric cancer in japan was evaluated. | 1994 | 8194007 |
| natural gastric infection with helicobacter pylori in monkeys: a model for spiral bacteria infection in humans. | there is no generally accepted model for helicobacter pylori infection in humans. the aim of this study was to examine the natural history and effect of treatment in rhesus monkeys and sequentially define the immune response to h. pylori in relation to treatment. | 1994 | 8194685 |
| bisulfite or sulfite inhibits growth of helicobacter pylori. | bisulfite or sulfite was found to be inhibitory to helicobacter pylori growth. a modified version of brucella broth (bb), bisulfite-less bb (blbb), supported rapid, robust, and consistent growth of h. pylori. we suggest that blbb simply be called "pylori broth" for distinction from brucella broth. | 1994 | 8195395 |
| [immunohistochemical study of helicobacter pylori and mononuclear cells in the gastric mucosa of patients with gastritis or peptic ulcer]. | the distribution and localization of helicobacter pylori (hp) and mononuclear cells (mnc) in the gastric mucosa were investigated immunohistochemically in 120 patients with gastritis or peptic ulcer. hp was detected in the gastric mucosa of 58% of 40 gastritis patients, 82% of 56 gastric ulcer (gu) patients, and 88% of 24 duodenal ulcer (du) patients. in the hp-positive mucosa, cells positive for igg or iga were increased significantly when compared to the hp-negative mucosa. neutrophils and eos ... | 1994 | 8196206 |
| [omeprazole modified antibiotic therapy of helicobacter pylori infection: can clarithromycin be replaced by roxithromycin?]. | thirty-five consecutive patients (median age: 50 years, 17 men and 18 women) suffering from helicobacter pylori associated peptic ulcer disease (duodenal ulcer: n = 15, gastric ulcer: n = 13) or severe functional dyspepsia (n = 7) were enrolled in a two-center clinical trial and treated with omeprazole 20 mg bid preprandially and roxithromycin 300 mg bid postprandially over two weeks. after cessation of the study medication, ulcer patients received a full dose h2-blocker treatment up to the fina ... | 1994 | 8196468 |
| blood type and the risk of gastric disease. | 1994 | 8197448 | |
| enhanced mucosal interleukin-6 and -8 in helicobacter pylori-positive dyspeptic patients. | to determine the concentrations of interleukin-1 beta, interleukin-6, and interleukin-8 in tissue homogenates of mucosal biopsy specimens from helicobacter pylori-positive and -negative patients. | 1994 | 8198099 |
| decrease in ornithine decarboxylase activity after eradication of helicobacter pylori. | our aim was to determine whether gastric mucosal odc activity is altered after successful eradication of hp. recent reports have suggested that helicobacter pylori (hp) infection of the stomach is associated with the development of gastric cancer. gastrointestinal cancers usually do not arise de novo; a series of mucosal changes leading to neoplastic transformation and degrees of dysplasia are believed to precede the development of cancer. these conditions are associated with increased cellular ... | 1994 | 8198100 |
| omeprazole/amoxicillin versus ranitidine/triple therapy for duodenal ulcer: when is the "same" the same? | 1994 | 8198114 | |
| cytoprotection with misoprostol: use in the treatment and prevention of ulcers. | prostaglandins protect the gastric mucosa by decreasing gastric acid secretion, increasing mucus and bicarbonate production and maintaining mucosal blood flow. non-steroidal anti-inflammatory drugs (nsaids) cause gastroduodenal damage and this is due, at least in part, to inhibition of mucosal prostaglandin production. misoprostol is a synthetic analogue of prostaglandin e1 which has been used in the healing of ulcers and prevention of peptic ulcers in patients taking nsaids. misoprostol is of e ... | 1994 | 8200123 |
| the relationship between helicobacter pylori-associated gastritis or ulcer disease and gastric emptying. | forty-five patients with helicobacter pylori (hp)-associated gastritis or ulcer disease were included in this study. radionuclide-labelled solid meals were used to calculate gastric emptying times (gets) and carbon-14 urea breath tests (14c ubts) were used to measure the hp colonies quantitatively. the patients were assessed according to the following two criteria: (a) the hp colony number (i.e. high or low) and (b) the recorded duration of the get (i.e. long or short). there was no statisticall ... | 1994 | 8200387 |
| healing of protein losing hypertrophic gastropathy by eradication of helicobacter pylori--is helicobacter pylori a pathogenic factor in ménétrier's disease? | hypertrophic gastropathy--that is, ménétrier's disease--was found, in a retrospective analysis, to be associated with helicobacter pylori in more than 90% of patients. it is proposed that hypertrophic gastropathy represents a special form of h pylori gastritis in these patients. a case is described of a 28 year old woman with ménétrier's disease associated with proved protein loss from the stomach. treatment with cimetidine for more than three years had little benefit when colonisation by h pylo ... | 1994 | 8200570 |
| helicobacter pylori infection. | 1994 | 8200579 | |
| [biotechnology vaccines--development of new disease prevention. research progress of biocine in siena--hiv, herpes, helicobacter]. | 1994 | 8200601 | |
| ranitidine and recurrent hemorrhage from duodenal ulcer. | 1994 | 8202110 | |
| are tryptase and cathepsin d related to helicobacter pylori infection and mucosal gastrin in peptic ulcer? | the pathogenesis of peptic ulcer is a complex phenomenon and several factors are thought to be involved in this process. among others, helicobacter pylori infection, hypergastrinaemia and some proteases seem to play an essential role in inducing peptic ulceration. we investigated whether tryptase (a serine endoprotease released by mast cells) and cathepsin d (a lysosomal hydrolase which seems able to derange the extracellular matrix) play a part in peptic ulcer disease and whether they are linke ... | 1994 | 8202635 |
| helicobacter pylori colonization in children with gastritis and peptic ulcer. i. the colonization rate and effects of colonization on mucin content and mucosal inflammation in the antrum. | the incidence of helicobacter pylori infection and effects of h. pylori colonization on mucin content and mucosal inflammation of the antral mucosa were studied quantitatively in 55 japanese children with suspected gastritis and peptic ulcers (aged 6-16 years, mean 12.3 years). h. pylori was detected, using warthin-starry stain, in nine of the 22 cases (41%) with antral histological gastritis, but in none of the 33 histologically normal cases. five out of seven duodenal ulcer cases showed histol ... | 1994 | 8203261 |
| helicobacter pylori colonization in children with gastritis and peptic ulcer. ii. ultrastructural change of the gastric mucosa. | to evaluate the role of helicobacter pylori in the pathogenesis of gastritis and peptic ulcer in children, ultrastructural changes of the gastric mucosa with h. pylori colonization were studied in two pediatric patients with duodenal ulcers. the study demonstrated that h. pylori: (i) colonized the mucous layer covering normal gastric epithelium; (ii) lay atop short, irregular microvilli and at the intercellular junctions of damaged cells; and (iii) adhered firmly by specific junction zone (firm ... | 1994 | 8203262 |
| resistance to the nitroheterocyclic drugs. | the nitroheterocyclic drugs have been available since the early 1960's for the treatment of anaerobic protozoa. the application of these drugs has widened since then and they are presently used to treat anaerobic pathogenic bacteria and protozoa. the activity of the nitroheterocyclic drugs depends on the all-important nitro group attached to the imidazole or furan ring. although the nitro radicals, generated by reduction of the parent drugs, are similar for both families of nitroheterocyclics, t ... | 1994 | 8203303 |
| [the psychological characteristics of dyspepsia. a controlled study with gastroscopic follow-up]. | it's known that some psychologic factors could be implicated in dyspepsia. therefore, the psychologic aspects of 38 dyspeptic patients (17 males, 21 females, aged 18-65 years), who underwent digestive endoscopy, were evaluated by means of rorschach and mmpi test. patients with previous peptic ulcer history, with chronic ethanol or nsaid intake, operated on digestive tract and patients with behavioural problems were excluded. the results of psychological tests enhanced two main groups: anxiety pa ... | 1994 | 8204702 |
| [azithromycin-omeprazole. treatment for the eradication of helicobacter pylori]. | to evaluate the benefit of 4-week regimen including azithromycin+omeprazole (vs omeprazole alone) for eradication of helicobacter pylori. | 1994 | 8204705 |
| current diagnosis and treatment of helicobacter pylori. | 1994 | 8191764 | |
| helicobacter pylori, the pathologist's point of view. | 1994 | 8191856 | |
| in vitro studies on stability and development of metronidazole resistance in helicobacter pylori. | seventy isolates of helicobacter pylori from antral biopsy samples were tested for their susceptibilities to metronidazole by agar dilution. seven (10%) of these clinical isolates appeared to be resistant to metronidazole. sixty-three strains were susceptible. in 42 (67%) of the 63 susceptible isolates, resistant isolates were obtained by serial passage on plates containing subinhibitory concentrations of metronidazole. in 10 of these 42 strains, the acquired resistance appeared to be unstable. ... | 1994 | 8192465 |
| medium- or high-dose omeprazole plus amoxicillin eradicates helicobacter pylori in gastric ulcer disease. | to compare the efficacy of two omeprazole/amoxicillin regimens concerning helicobacter pylori eradication, ulcer healing, pain relief, and safety in patients with gastric ulcer disease. | 1994 | 8172146 |
| seasonal variation in the frequency of helicobacter pylori infection: a possible cause of the seasonal occurrence of peptic ulcer disease. | the seasonal variation of duodenal ulcer disease and its complications have been repeatedly demonstrated in israel by several independent studies. the aim of this study was to determine possible seasonal variations in the occurrence of h. pylori infection among dyspeptic patients in israel. | 1994 | 8172147 |
| evaluation of 14c-urinary excretion and its comparison with 14co2 in breath after 14c-urea administration in helicobacter pylori infection. | 1) to estimate levels of 14c-urinary excretion in helicobacter pylori-infected and noninfected patients after 14c-urea ingestion, 2) to compare 14c-urinary excretion and 14co2 breath results with biopsy findings, and 3) to find out correlation between 14c-urinary excretion with 14co2 breath results, if any. | 1994 | 8172148 |
| prolonged bedtime treatment with h2-receptor antagonists (ranitidine and famotidine) does not affect blood alcohol levels after ethanol ingestion in male patients with duodenal ulcer. | to verify whether a prolonged (therapeutic) treatment with ranitidine or famotidine may affect blood alcohol concentrations (bac) in patients with duodenal ulcer (du). | 1994 | 8172150 |
| epidemiology of non-hodgkin's lymphoma: recent findings regarding an emerging epidemic. | between 1973 and 1989, the incidence of non-hodgkin's lymphoma (nhl) increased by nearly 60% in the united states, one of the largest increases of any cancer. in 1993, approximately 43,000 new cases of nhl will be diagnosed and over 20,000 deaths due to nhl will occur. the annual incidence rate of nhl per 100,000 persons in the us has risen from 5.9 in 1950 to 13.7 in 1989. this increase has occurred in both males and females, blacks and whites, and in all age groups except the very young. the l ... | 1994 | 8172811 |
| [swedish patients with stomach ulcer do not receive optimal treatment]. | 1994 | 8189933 | |
| [optimal treatment of helicobacter pylori infections is not known. more clinical trials on elimination are necessary]. | 1994 | 8189935 | |
| [a new clinical strategy in peptic ulcer disease. suggestions for the elimination of helicobacter pylori]. | 1994 | 8189937 | |
| [diagnosis of helicobacter pylori infection]. | 1994 | 8189938 | |
| [indications for therapy against helicobacter pylori]. | 1994 | 8189939 | |
| [choice of therapy (helicobacter infection)]. | 1994 | 8189940 | |
| [follow-up of the therapeutic effect and strategy in non-elimination]. | 1994 | 8189941 | |
| [quality assurance in everyday routines]. | 1994 | 8189942 | |
| [duodenal ulcer disease: a defect in the secretory immune response to helicobacter pylori?]. | in a prospective study we examined 20 helicobacter pylori (hp)-positive duodenal ulcer patients (5 female, 15 male; age 26-70 [mean 43] years), 20 hp-positive patients with non-ulcer dyspepsia (10 female, 10 male; age 26-79 [mean 48] years) and 10 hp-negative patients with non-ulcer dyspepsia (5 female, 5 male; age 21-76 [mean 45] years) during upper gi-endoscopy. hp was detected by histology (h&e, giemsa), rapid urease test (clo) and serology (cobas core anti-h. pylori eia). iga anti-hp in gast ... | 1994 | 8191263 |
| [suppression of helicobacter pylori by local secretory immune response?]. | 54 patients (22 females, 32 males, age 21-79, mean 45 years) referred for upper gastrointestinal endoscopy were investigated. helicobacter pylori (hp) infection was determined using histology (h&e and giemsa stain), rapid urease test (clo) and serology (cobas core anti-h. pylori eia). density of hp colonization was determined in gastric antral (3 biopsy specimens) and body mucosa (2 biopsy specimens) and semiquantitatively graded on a scale of 0 to 3. gastric colonization was obtained by additio ... | 1994 | 8191264 |
| [alternatives of drug therapy in helicobacter pylori infections]. | the last three years of research on treatment of helicobacter pylori infection support the recommendations made by the working party, world congress of gastroenterology 1990. meta-analysis shows a noteworthy difference between the recommended regimens favouring the combination of bismuth, metronidazole and tetracycline. no regimen without bismuth has been shown to have a sustained helicobacter pylori eradication rate exceeding 90%, nor has any alternative regimen been shown convincingly to stem ... | 1994 | 8191471 |
| helicobacter pylori eradication, duodenal ulcer healing, and gastric secretory state. | 1994 | 8175003 | |
| helicobacter pylori eradication with bismuth subnitrate, oxytetracycline and metronidazole in patients with peptic ulcer disease. | a total of 152 patients with recurrent peptic ulcer disease were treated with bismuth subnitrate, oxytetracycline and metronidazole. the 51 patients in group 1 were included following a study of the effect of cognitive psychotherapy on the recurrence rate after curative treatment for duodenal ulcer (du). group 2 comprised 101 consecutive patients referred to us with recurrent peptic ulcer. their helicobacter pylori (hp) status was assessed before, and 4 weeks after, discontinuation of treatment, ... | 1994 | 8175114 |
| helicobacter pylori: incidence and comparison of three diagnostic methods in 196 saudi patients with dyspepsia. | one hundred and ninety-six symptomatic saudi patients with dyspepsia underwent gastroscopy, and multiple biopsies were taken from the antrum of the stomach for identification of helicobacter pylori. three methods were studied for diagnosis of helicobacter pylori, including urease test, culture and histopathology. the commonest gastroscopic findings were gastritis in 82 patients (41.84%) and duodenal ulcer in 40 patients (20.41%). among the 196 patients, helicobacter pylori was identified by hist ... | 1994 | 8175115 |
| idiotype identity in a malt-type lymphoma and b cells in helicobacter pylori associated chronic gastritis. | to investigate the mechanisms triggering malt-lymphoma development, we examined the occurrence of normal b cells in lymphoid tissue and chronic gastritis with the same idiotype as an iga-positive malt lymphoma. | 1994 | 8176897 |
| helicobacter pylori and nucleolar organizer regions in the gastric antral mucosa. | the association of helicobacter pylori with an increased risk of gastric adenocarcinoma has been documented, but its mechanisms have not been elucidated. this study explored these mechanisms by addressing the relationship between h pylori and the silver-staining nucleolar organizer regions (agnors) in the gastric antrum. the number of agnors per nucleus has been correlated with proliferative rate and ploidy. the results of gastric biopsies performed before and after treatment for h pylori showed ... | 1994 | 8178774 |
| omeprazole-induced increase in the absorption of bismuth from tripotassium dicitrato bismuthate. | omeprazole is an effective drug for treating active peptic ulcer, whereas tripotassium dicitrato bismuthate can prevent ulcer relapse if helicobacter pylori is eradicated. because both drugs will be given concomitantly, drug interactions have to be considered, especially since absorption of bismuth may be dependent on intragastric ph, which will be elevated by omeprazole. | 1994 | 8181192 |
| lack of protection against gastric helicobacter infection following immunisation with jack bean urease: the rejection of a novel hypothesis. | the common mucosal immune system was stimulated by oral immunisation with jack bean urease and the adjuvant cholera toxin. a high level of local antibody and serum antibody was induced in mice following hyperimmunisation with this combination. no cross-reacting antibody was found against either helicobacter pylori or helicobacter felis. no protection was observed against oral challenge of immunised mice with living h. felis thus disproving the interesting hypothesis of pallen and clayton that pl ... | 1994 | 8181696 |
| giardiasis of the stomach. | a patient with giardiasis in an inflamed gastric antral biopsy specimen is reported. helicobacter pylori were not identified and no other cause of the gastritis was apparent. this condition may be more common than has been previously supposed and may be linked to bile reflux or hypochlorhydria. | 1994 | 8183764 |
| elimination of recurrent hyperplastic polyps by eradication of helicobacter pylori. | 1994 | 8185131 | |
| familial helicobacter pylori infection. societal factors, human genetics, and bacterial genetics. | 1994 | 8185136 | |
| helicobacter pylori infection: genetic and environmental influences. a study of twins. | to investigate the importance of genetic effects for acquiring helicobacter pylori infection. | 1994 | 8185146 |
| [helicobacter pylori, one step further]. | 1994 | 8186000 | |
| a comparison of 16s ribosomal dna sequences from five isolates of helicobacter pylori. | other workers have found that clinical isolates of helicobacter pylori exhibit very extensive dna sequence polymorphisms when they are examined by ribotyping or some other genomic sequence characterization technique. in fact, it is rare to find similar clones, much less identical ones, among isolates. we found that the levels of divergence between the 16s ribosomal dna sequences of individual organisms and the consensus sequence of the five isolates which we examined ranged from 0.2 to 0.5%. in ... | 1994 | 8186097 |
| short report: clarithromycin, an alternative to metronidazole in the triple therapy of helicobacter pylori infection. | triple therapy for helicobacter pylori using metronidazole is less effective in patients with a metronidazole resistant strain. moreover, metronidazole is responsible for many side-effects. this open study examined the efficacy and side-effects of a triple treatment regimen substituting clarithromycin for metronidazole. | 1994 | 8186339 |
| zollinger-ellison syndrome and antral g-cell hyperfunction in patients with resistant duodenal ulcer disease. | we measured basal and pentagastrin-stimulated acid secretion, as well as basal and meal-stimulated plasma gastrin concentration to determine, in 67 patients affected by resistant duodenal ulcer, whether their condition could be related to gastric acid secretion and/or gastrin-related syndromes. we then compared them to 46 duodenal ulcer control patients. the outpatients were investigated consecutively. the resistant duodenal ulcer patients differed from the controls only in their higher complica ... | 1994 | 8186351 |
| [the therapy of helicobacter pylori infection]. | 1994 | 8187614 | |
| molecular structures that influence the immunomodulatory properties of the lipid a and inner core region oligosaccharides of bacterial lipopolysaccharides. | the relationship between chain length as well as the position of fatty acyl groups to the ability of lipid a to abolish the expression of suppressor t-cell (ts) activity was examined. fatty acyl chain lengths of c12 to c14, as in the lipid a of escherichia coli and salmonella minnesota, appear to be optimal for this bioactivity, since lipid a preparations with fatty acyl groups of relatively short chain length (c10 to c12 for pseudomonas aeruginosa and chromobacterium violaceum) or predominantly ... | 1994 | 8188347 |
| helicobacter pylori isolated from the domestic cat: public health implications. | helicobacter pylori has been directly linked with active chronic gastritis, peptic ulceration, and gastric adenocarcinoma in humans. although a substantial portion of the human population is colonized with h. pylori, the patterns of transmission of the organism remain in doubt, and reservoir hosts have not been identified. this study documents the isolation of h. pylori from domestic cats obtained from a commercial vendor. the isolation of h. pylori from these cats was confirmed by morphologic a ... | 1994 | 8188360 |
| mutation of the cytotoxin-associated caga gene does not affect the vacuolating cytotoxin activity of helicobacter pylori. | helicobacter pylori now is recognized as an etiological agent in chronic superficial gastritis and peptic ulcer disease. although only about 60% of h. pylori isolates produce an immunodominant 128-kda antigen (caga; cytotoxin-associated gene product), virtually all h. pylori-infected patients with duodenal ulceration develop a serologic response to the 128-kda protein, which suggests an association of this gene with ulceration. the cloned caga gene from h. pylori 84-183 was disrupted by insertio ... | 1994 | 8188385 |
| helicobacter pylori-associated peptic ulcer in heterotopic gastric mucosa within ileal duplication. | a 12-year-old boy, operated on for remitting abdominal pain and hematochezia, had an ileal duplication, with helicobacter "gastritis" under a chronic peptic ulcer in the ectopic fundic gastric mucosa. we suggest the helicobacter infection might have played a role in the pathogenesis of the inflammation and the peptic ulceration in this rare location. | 1994 | 8189008 |
| peptic ulcer disease mortality. comparison of native japanese, japanese americans, and caucasian americans. | peptic ulcer disease mortality patterns of california japanese are compared with those of their home and host countries for even years from 1960 to 1988, as well as 1989. data presented are consistent with the hypothesis that helicobacter pylori is a necessary but not sufficient causal factor in peptide ulcer disease, and that other co-factors including cigarette smoking and salt intake may be important. deaths due to peptic ulcer numbered 106 among california japanese, 12,793 for california cau ... | 1994 | 8189011 |
| helicobacter pylori infection and peptic ulcer disease in cameroon, west africa. | 1994 | 8189016 | |
| a gastroscopic study of the predictive value of risk factors for non-steroidal anti-inflammatory drug-associated ulcer disease in rheumatoid arthritis patients. | peptic ulcer disease (pud) in ra patients is associated with nsaid use. this study aimed to validate the predictive value of presumed risk factors for nsaid-associated pud in a prospective gastroscopic study in ra patients. eighty-one nsaid using ra patients were prospectively divided into four presumed risk groups according to helicobacter pylori status and history of pud. as additional risk factors the following were analysed: upper gastrointestinal gi complaints; disability; daily dose of nsa ... | 1994 | 8173849 |
| interrelationships between helicobacter pylori infection, nonsteroidal antiinflammatory drugs and gastroduodenal disease. a prospective study in healthy volunteers. | helicobacter pylori and nonsteroidal antiinflammatory drugs independently cause gastroduodenal mucosal injury but the relationship between them remains unclear. we have performed a double-blind, parallel-group, placebo-controlled prospective study in 77 healthy volunteers aged 19-35 years who were randomly allocated to indomethacin (n = 15), one of three oxicams (piroxicam, chlortenoxicam, or chf 1194; n = 36), or placebo (n = 26). esophagogastroduodenoscopy was performed before and after four w ... | 1994 | 8174421 |
| dyspepsia in healthy blood donors. pattern of symptoms and association with helicobacter pylori. | whether helicobacter pylori is causally linked to dyspepsia remains controversial. the aims of this study were to assess in healthy blood donors the prevalence of dyspepsia and dyspepsia subgroups, determine if h. pylori is associated with different categories of dyspeptic symptoms, and evaluate the association between dyspepsia and nicotine, alcohol, and analgesic use. consecutive blood donors (n = 180) who had no clinical evidence of organic disease were included. abdominal symptoms were measu ... | 1994 | 8174422 |
| a critique of therapeutic trials in helicobacter pylori-positive functional dyspepsia. | approximately 50% of patients with functional dyspepsia have helicobacter pylori infection; it remains controversial whether this infection causes chronic symptoms, but rigorously conducted therapeutic trials should establish whether h. pylori plays a role in functional dyspepsia. the aim here was to determine whether the trials published over the past 10 years were methodologically adequate to establish a role for this infection in functional dyspepsia. | 1994 | 8174880 |
| plasma gastrin concentrations are normal in patients with colorectal neoplasia and unaltered following tumor resection. | previous studies have found that colorectal cancer patients have hypergastrinemia, but most have been inadequately controlled. preoperative fasting and meal-stimulated gastrin levels were measured in patients with colorectal tumors (n = 42) and in carefully matched controls (n = 34). helicobacter pylori status was assessed because it causes significant hypergastrinemia. | 1994 | 8174887 |
| h. pylori and gastric cancer: limitations of retrospective studies. | 1994 | 8174905 | |
| nonopsonic activation of neutrophils and cytotoxin production by helicobacter pylori: ulcerogenic markers. | fifty-four clinical isolates of helicobacter pylori from human gastric biopsy specimens were tested for cytotoxin production, as determined by intracellular vacuolization of hela cells, and for the induction of oxidative burst in human polymorphonuclear leukocytes (pmnls), as measured by luminol-enhanced chemiluminescence (cl). nonopsonized, 20 of the h. pylori strains induced a rapid and strong cl response, in contrast to 30 other strains, which showed only weak and slow responses. another four ... | 1994 | 8171279 |
| helicobacter pylori-associated gastritis and dyspepsia. the influence on migrating motor complexes. | twenty-five patients with dyspepsia were included. in 19 patients with a median age of 48 (range, 20-72) years endoscopy and histologic examination of biopsy specimens from the antrum and corpus of the stomach showed helicobacter pylori-positive gastritis as the only pathologic finding. in six patients with a median age of 42 (range, 32-56) years h. pylori-negative gastritis was found. after an overnight fast the patients underwent an ambulatory duodenal motility study for 6-8 h. twenty-five you ... | 1994 | 8171280 |
| seroprevalence of helicobacter pylori infections in a cohort of us army recruits. | to study the prevalence and risk factors of helicobacter pylori infection in healthy young adults, sera were collected from a nationwide sample of 404 females and 534 males (mean age, 20.2; range, 17-26 years) at induction into the us army at fort jackson, south carolina, during the fall of 1990. an enzyme-linked immunosorbent assay (pylori stat, biowhittaker, inc., walkersville, md) was used to detect h. pylori-specific immunoglobulin g antibodies. demographic data were obtained from a personne ... | 1994 | 8154475 |
| assessment of helicobacter pylori infection. | 1994 | 8158584 | |
| [the characteristics of duodenogastric reflux in peptic ulcer and chronic gastritis]. | patients with gastroduodenal ulcer, chronic gastritis (cg) and healthy controls (124, 57 and 24 subjects, respectively) were examined for intensity and duration of duodenogastric reflux (dgr). these indices were assessed by concentrations of gastric juice bilirubin. it is found that dgr occurred in 29% of the examinees free of gastroduodenal diseases, does not correlate with morphological cg-induced changes and helicobacter pylori contamination degree. the reflux in cg seems to be secondary in p ... | 1994 | 8160143 |
| [the pharmacodynamic and ulcer-healing action of modern anti-ulcer agents]. | in a study of 159 duodenal ulcer patients the authors studied the effect of h2-blockers, antibacterial and sucralfate monotherapy on the frequency of the ulcer healing, helicobacter pylori (hp) infection and acid-proteolytic aggression in the body and antropyloric portion of the stomach. all the drugs were found to exhibit similar antiulcer activity. inhibition of the acid-proteolytic aggression in the gastric body was registered only under the action of h2-blockers. antibacterial preparations i ... | 1994 | 8160144 |
| isolation of helicobacter strains from wild bird and swine feces. | we report the first isolations of helicobacter strains from wild birds and swine. genus-specific oligonucleotide probes identified nine cape cod isolates from gull, tern, house sparrow, and pig feces as helicobacter spp. and not campylobacter spp. antibiotic sensitivity and urease tests distinguished three phenotypes. strains examined rapidly lost culturability under simulated natural conditions. | 1994 | 8161169 |
| campylobacter meets helicobacter in brussels. | 1994 | 8162436 |