Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| mode of subacute sclerosing panencephalitis (sspe) virus infection in tissue culture cells. ii. cell-free viruses in cell cultures infected with kitaken-1 and biken strains of sspe virus. | cell-free infectious viruses were successfully recovered by the aid of freezing and thawing from cultures infected with the kitaken-1 and biken strains of subacute sclerosing panencephalitis (sspe) virus. our results including those in a previous report which dealt with the niigata-1 strain of sspe virus show that cell-free viruses can be detected from all of the sspe virus-carrying cultures established in japan. it was also found that cell-free infectious viruses can be recovered efficiently by ... | 1980 | 7219204 |
| [serological assay of measles and rubella immunity in a sample of infantile population in palermo (author's transl)]. | the antibodies to measles and rubella viruses were titrated in a sample of infantile population in palermo in 1978. measles antibodies were investigated in 900 children aged 0-15 years by the hi test; rubella antibodies in 120 girls aged 12-14 years by the hemolysis-in-gel test. a "saturation" level of immunity against measles virus as can be found in the adult population appeared to be attained at the age of 12-13 years. at this age however, about 28% of the girls were still not immunized again ... | 1980 | 7247483 |
| measles-specific antibodies in sera and cerebrospinal fluids of patients with multiple sclerosis. | immunoprecipitation methods were used to analyze sera and cerebrospinal fluids from patients with multiple sclerosis for measles virus-specific antibodies. the sera contained antibodies against all virus antigens except the matrix polypeptide. of the nine cerebrospinal fluids investigated, two contained undetectable levels of measles-specific antibodies, four contained antibodies against the nucleocapsid and another internal antigen, and three contained antibodies against the surface antigens as ... | 1980 | 6991427 |
| multiple sclerosis in the orkney and shetland islands. iv: viral antibody titres and viral infections. | a controlled serologic survey of antibody titres to 17 viruses was undertaken in multiple sclerosis patients in the orkney and shetland islands. no consistent pattern of elevated antibody titre levels or the presence of antibody was noted in patients compared with two control groups. because of the isolation of these islands, the mean age at acquisition of common childhood infections, including measles, was considerably older than that of inhabitants of europe and the united states of america. t ... | 1980 | 7241024 |
| measles retinopathy. a hamster model of acute and chronic lesions. | measles and subacute sclerosing panencephalitis strains of virus inoculated intracerebrally in suckling and weanling hamsters spread immediately to the eye via the blood. virus replicates in the brain and eye in parallel, and in higher titers than it does in other organs. acute retinal lesions consist of focal syncytia, inclusion-bearing cells, and necrosis. immunofluorescence studies show measles-specific antigen in the affected cells. ultrastructurally, measles nucleocapsids and virions are se ... | 1980 | 6993787 |
| [subacute sclerosing panencephalitis: correlation between immunologic and histopathologic aspect]. | 1980 | 7231160 | |
| [in-vitro block of granulocyte chemotaxis with attenuated measles virus]. | live attenuated measles virus preparations, which are in use today in the prophylaxis against measles, were added in vitro to neutrophils from healthy children with negative history both for measles infection and vaccination. after incubation at 37 degree c for 30 min, and washing in hank's solution, chemotaxis was assayed in sykes-moore chambers. bacterial endotoxin and sera from healthy donors were used to stimulate motility. a significant decrease in chemotaxis was shown by virus-incubated ne ... | 1980 | 7271342 |
| [preliminary data on some virological and immunological aspects of subacute sclerosing panencephalitis]. | 1980 | 7294911 | |
| preparation and characterization of high-specific activity radiolabeled 50 s measles virus rna. | a method is described to radiolabel measles virus rna for hybridization studies. tritiated nucleosides were added to the media of measles virus infected vero cells and negative-strand (genome) rna with a specific activity of 6 x 10(5) c.p.m./microgram was purified from viral nucleocapsids. 50 s rna was the sole rna present in nucleocapsids and self-annealed to 50% due to the presence of 25% 50 s plus-strands (anti-genomes). | 1980 | 7276125 |
| [microplaque formation by carboxymethyl cellulose overlay of morbilliviruses and its application to neutralization test (author's transl(]. | 1980 | 7331239 | |
| the polypeptides of canine distemper virus: synthesis in infected cells and relatedness to the polypeptides of other morbilliviruses. | 1980 | 7352374 | |
| immune responses to measles and smallpox vaccinations in malnourished children. | children with different levels of nutritional status were studied to determine their immune response to, and complications from, immunization with live measles vaccine and lyophilized smallpox vaccine. two hundred forty-one children between the ages of 5 months and 9 years were examined to assess their nutritional status at the time of immunization. sero-conversion was defined as a hemagglutination-inhibition titer to measles virus, of greater than or equal to 1:20 6 to 8 weeks after vaccination ... | 1980 | 7355846 |
| nosocomial management of resistant gram-negative bacilli. | 1980 | 7365287 | |
| isolation and partial characterization of two forms of cytoplasmic nucleocapsids from measles virus-infected cells. | two species of measles virus nucleocapsids with distinct buoyant densities were isolated from infected av3 cell homogenates by isopycnic cscl gradient centrifugation. the more buoyant or 'light' form of the nucleocapsid had a density of 1.26 to 1.28 g/ml, whereas the less buoyant or 'heavy' nucleocapsid species had a density of 1.30 g/ml. analysis of the two nucleocapsid species by sds--polyacrylamide gel electrophoresis showed that both forms possessed two phosphorylated polypeptides with mol. ... | 1980 | 7365470 |
| further studies on subacute encephalitis and hydrocephalus in hamsters caused by measles virus from persistently infected cell cultures. | newborn hamsters were inoculated intracerebrally (ic) with disrupted measles carrier lu 106 cells. no acute neurological disease developed, but limited, persistent neural infection was identified by immune fluorescence and by virus isolation. by ten days after inoculation, virus could be recovered only by cocultivation of explant cultures of central nervous system (cns) tissue and vero cells. virus was still demonstrable in cns by both techniques 50 days after inoculation, the latest sample coll ... | 1980 | 7373285 |
| differences in early ultrastructural aspects of the replication of measles and subacute sclerosing panencephalitis viruses in a cell culture from a human astrocytoma. | monolayer cultures from a human astrocytoma were infected with small amounts of mantooth subacute sclerosing panencephalitis (sspe) and edmonston measles viruses. the infected cells were studied with an electron microscope 48 hours and 96 hours post-inoculation (pi). by 48 hours pi, both viruses produced syncytia and cytoplasmic inclusions of granular nucleocapsids 20 to 25 nm in diameter which did not differ in appearance. with the edmonston measles virus granular nucleocapsids assembled into b ... | 1980 | 7373346 |
| [the state of measles immunity and the success quota of measles vaccination in basle nursery and elementary school pupils]. | measles antibody determinations in kindergarten and primary school children in basle-city showed that today just under 10% of 10-year-olds and roughly 25% of 5-year-olds have no immunity to measles. in the 10-year-old primary school children the effects of measles immunization are not yet markedly apparent, whereas almost half the kindergarten children already owe their measles immunity to immunization. no measles antibodies could be detected in 13,7% of the subjects who, according to their offi ... | 1980 | 7375902 |
| subacute sclerosing panencephalitis and defective interfering measles virus particles. | 1980 | 7376464 | |
| antibodies against the measles matrix polypeptide after clinical infection and vaccination. | sera from patients exposed to measles virus were investigated for the presence of antibodies against each of the viral antigens. all sera with measurable neutralizing titers contained antibodies against the two surface proteins (the glycoprotein and fusion protein), the nucleocapsid protein, and one of the internal proteins (p2). however, only sera from individuals with clinical symptoms of measles infection (natural measles and atypical measles) contained antibodies against the measles virus ma ... | 1980 | 7380553 |
| [serological studies of the immunological condition versus rebulla virus in maternal and neonatal serum samples]. | in 116 serum pairs sampled from the mother and the newborn at delivery, the antibody level against rubeola virus has been assessed haemagglutination inhibition test. thirty one per cent of the mothers resulted not protected, as the antibody titer was below 1/16. a situation akin to that described in the same percentage of not protected women was 29,45%. in 19% of the newborns the antibody level against the virus proved higher than the mother's one by at least two dilution factors. research work ... | 1980 | 7387787 |
| atypical measles in adolescent siblings 16 years after killed measles virus vaccine. | the history of killed and live measles vaccine administration and exposure to natural disease is detailed in four adolescent siblings over a 16-year period. in two of these siblings, atypical measles developed 16 years after killed measles virus vaccine was administered, despite intercurrent doses of live measles virus vaccine. | 1980 | 7392190 |
| [status of immunization against measles in the pediatric population of the province of ferrara]. | 1980 | 7393191 | |
| natural and immune cytolysis of canine distemper virus-infected target cells. | natural and immune cytolysis of canine distemper virus (cdv)-infected target cells in vitro is described. lymphocytes expressing natural cytotoxicity were found in specific-pathogen-free beagle dogs and in beagle-coonhound crosses before vaccination with cdv and indefinitely after vaccination, when the ephemeral immune lymphocyte-mediated cytotoxicity (ilmc) had declined. in contrast to the natural lymphocyte-mediated cytotoxicity, the ilmc was genetically restricted, could not be blocked by cdv ... | 1980 | 7399692 |
| hla-b8, immunoglobulins, and antibody responses in alcohol-related liver disease. | ninety-two british, caucasian, alcoholic patients with liver disese were grouped on the basis of hepatic histology into fatty change, hepatitis with or without cirrhosis, and cirrhosis alone. men with alcoholic hepatitis with or without cirrhosis showed an increased incidence of the histocompatibility antigen hla-b8 (p less than 0.02). increased measles antibody titres were found in patients without cirrhosis with or without hepatitis and were associated with the b8 phenotype in both sexes. rube ... | 1980 | 7400347 |
| immune regulation of experimental myasthenia. | experimental autoimmune myasthenia gravis (eamg) is an appropriate model for studying the molecular origin, immunological mechanism and regulation of myasthenia gravis. several approaches are being utilised for the regulation of the immune response to achr and for immunosuppression of eamg: corticosteriods and azathioprine can suppress eamg concomitantly with suppression of immune responses to achr. high dose cyclophosphamide treatment in mice facilitates the onset of eamg and results in a selec ... | 1980 | 7400824 |
| subacute sclerosing panencephalitis. | 1980 | 7403192 | |
| persistent measles virus infection in a calf kidney cell line. note iv. electron microscopic observations in the k-2 cell line. | an electron microscopic study was performed in the k-2 calf kidney cell line persistently infected with measles virus. aggregates of granular filamentous structures 20-30 nm in diameter were detected in the paranuclear zone of the cytoplasm. rare, isolated smooth filaments 15-17 nm in diameter were also observed. no such structures were seen in the nucleus. the budding process was very active. many pleomorphic particles ranging in diameter from 100 to 600 nm were observed at the cell surface and ... | 1980 | 7405011 |
| a simplified plaque assay system for measles virus. | 1980 | 7410445 | |
| involvement of the central nervous system in acute, uncomplicated measles virus infection. | a prospective study on acute, uncomplicated measles infection was carried out in 59 patients hospitalized for an ordinary measles infection. a clinical and serological diagnosis of an acute measles infection was made in all cases. serial serum and cerebrospinal fluid (csf) specimens were taken two to five times from each patient and tested for pleocytosis, albumin, and measles-specific antibodies. pleocytosis was found in 18 patients (30%), usually shortly after the onset of rash. nine patients ... | 1980 | 7430331 |
| [congenital german measles encephalitis (author's transl)]. | german measles is an infections exanthematous disease, long regarded as completely harmless. the clinical symptoms are banal and often go unnoticed. in complete contrast is the severe malformation of the embryo after infection early on in pregnancy, first discovered by gregg in 1941. the virus infects the embryo via the placenta and either causes death or impairs the differentiation of embryonic tissues, causing malformation. what is understood today under the congenital german measles syndrome ... | 1980 | 7432807 |
| measles vaccination in zaïre--when and how? | of 121 children vaccinated for measles in zaïre, antibody studies revealed that 69% sero-converted. these included 53% of children vaccinated by two shots of a dermojet (0.2 ml i.d.) and 80% of children vaccinated by 0.5 ml subcutaneously. whilst a dermojet gives less good results, a decision on its use needs to be made in each individual situation, particularly taking into account the quantity of vaccine available for the number of children presenting for vaccination. at six months of age 59% o ... | 1980 | 7434432 |
| [epidemiologic characteristics of measles during a period of mass active immunization]. | 1980 | 7435011 | |
| modulation of the adherence of human lymphocytes to measles-infected cells by corticosteroids. | 1980 | 7438218 | |
| scanning and transmission electron microscopy study of antibody-dependent lymphocyte-mediated cytotoxicity on measles virus-infected cells. | the structural events related to antibody-dependent lymphocyte-mediated cytotoxicity (adlc) have been studied on measles virus-infected cells using human peripheral blood lymphocytes (pbl) and anti-measles virus serum. the first event in adlc was a recognition process occurring with 15 min after contact between the infected cells and lymphocytes. plasma membrane and microvilli of adsorbed pbl were specifically attached to virus-induced ridges over nucleocapsids and to viral buds. after 30 min, a ... | 1980 | 7439976 |
| chronic measles encephalitis in mice. | the intracerebral inoculation of hamster neurotropic measles virus produces a fatal acute encephalopathy in the majority of weanling balb/c mice. the few survivors remain healthy indefinitely. in contrast, weanling sjl/j mice are relatively resistant to acute encephalopathy, and about one-third of the survivors predictably develop a chronic encephalitis many weeks after inoculation. this later illness is characterized clinically by wasting, lethargy, seizures, or focal paralysis, usually culmina ... | 1980 | 7441020 |
| clq binding circulating immune complexes in multiple sclerosis patients and their first-degree relatives: a distinctive immunological feature between sporadic and familial cases. | circulating clq binding immune complexes were detected in 43% of sera from sporadic multiple sclerosis patients, in 52% of sera from the patients' first degree relatives and in 12% of normal sera studied, but not in 9 cases of familial multiple sclerosis nor in 24 of their 26 relatives. in sporadic cases, the presence of circulating immune complexes was not associated with any specific clinical form (progressive or remittent) nor with hypocomplementaemia. circulating immune complexes were found ... | 1980 | 7441712 |
| [current problems in the epidemiology and prevention of measles in the ukrainian ssr. reasons for the unfavorable epidemic situation with respect to measles which developed during the years of planned immunization]. | in the first years of specific mass immunization (1969--1971) the epidemic situation in the ukrainian ssr was more favorable than during the following period (1976--1977). with time after immunization the protection of the vaccinees decreased. the main reason of the measles virus circulation, of regular epidemics and the aggravation of the epidemic situation in 1976 and 1977 was the presence of 10% of seronegative children, which amounts to more than a million children unprotected against measle ... | 1980 | 7445862 |
| humoral immunity to canine distemper after immunization of dogs with inactivated and live measles virus. | pairs of dogs were immunized with 2 injections of a) measles virus material containing hemagglutinin but no hemolysin [tween 80 and ether (te) treated] b) material containing both hemagglutinin and hemolysin (freeze-dried and heated at 95 degrees c for 30 minutes), and c) live measles virus. two unimmunized dogs were used as controls. all 8 dogs were challenged with virulent canine distemper virus (cdv). the two unimmunized dogs contracted a lethal infection, whereas immunized animals only showe ... | 1980 | 7447704 |
| evidence for stimulation of glycerophospholipid synthesis in cultured human cells infected with measles virus. | change of lipid metabolism in fl cells derived from human amniotic membrane during fusion from within induced by measles virus was studied. the following results were obtained. (1) incorporation of [32p]orthophosphate and [methyl]-14c]choline into the lipid fraction of infected cells was higher than that of control cells. in this case, no detectable alteration of labeled phospholipid composition was observed. (2) radioactivity of the lipids in subcellular fractions of infected-cells labeled with ... | 1980 | 7419511 |
| an epizootic of measles in captive silvered leaf-monkeys (presbytis cristatus) in malaysia. | an epizootic of measles occurred in a group of 31 silvered leaf-monkeys (presbytis cristatus) that had been in captivity for 4-12 months. twenty-four of the monkeys exhibited a maculopapular rash that persisted for 6-9 days. a serous to mucopurulent nasal discharge and conjunctivitis were seen in some animals. eight monkeys died during the epizootic; however, their deaths could not be directly attributed to measles. serum samples from the surviving monkeys collected 1-2 months prior to, and 5 we ... | 1980 | 7421117 |
| measles virus infection of mouse neuroblastoma (c 1300) cells. | 1980 | 7422677 | |
| cellular cytotoxicity to measles virus during natural measles infection. | 1980 | 7460389 | |
| [determination of measles virus antibodies in the blood serum by enzyme-linked immunosorbent assay (elisa)]. | 1980 | 7464351 | |
| nontransmissibility of measles virus from vaccinated dogs to seronegative monkeys. | the nontransmissibility of the edmonston strain of measles virus was demonstrated by failure to transmit the virus by aerosol from vaccinated pups to susceptible cercopithecus monkeys. monkeys in direct contact for 3 weeks remained clinically normal and serologically negative for measles virus antibody. | 1980 | 7464777 |
| lymphocyte blast transformation responses in measles infection. | lymphocyte blast transformation responses were studied in eight patients with natural measles infection. a specific response to purified measles virus antigen and a weaker response to crude measles virus antigen were found after infection. the response to purified measles antigen appeared 1-3 weeks after the beginning of the rash, when the great number of proliferating mononuclear cells found in the peripheral blood during the rash was declining. in the first weeks after onset of the rash also l ... | 1980 | 7466326 |
| [analysis of the incidence of measles in karl-marx-stadt county with special reference to infants]. | 1980 | 7467502 | |
| [age-dependence of measles immunization failures]. | 1980 | 7467503 | |
| measles and canine distemper virus antibodies in patients with multiple sclerosis determined by radioimmunoassay. | 1980 | 7211163 | |
| no measles virus genetic information detected in multiple sclerosis--derived brains. | measles virus nucleotide sequences were searched for in diseased and normal-appearing white matter from brains of four multiple sclerosis victims. at the level of sensitivity established, 2.5 to 7.8 measles virus genome-equivalents of rna, or 4.9 genome-equivalents of putative dna per diploid cell quantity of dna, could have been detected. at these levels, no measles virus genetic information was found in any of the four brains. | 1980 | 7212651 |
| severe hypersensitivity or intolerance reactions to measles vaccine in six children. clinical and immunological studies. | six reported cases of anaphylactic reactions due to measles vaccinations of children were investigated. the reactions appeared to be immediate hypersensitivity reactions most probably due to allergy. trace amounts of calf serum proteins were demonstrated in the measles vaccine by means of crossed immunoelectrophoresis whereas egg antigens could not be detected by this method. the reason for the untoward reactions was not identified. atopic traits were not reported in any of the patients but were ... | 1980 | 7468944 |
| [the distribution of complement fixing antibodies against measles virus in a sample of population in emilia-romagna (author's transl)]. | 1980 | 7469536 | |
| [studies on establishment and maintenance of persistent infection with measles virus in nc-37 cell. 1. production of dna-synthesis-suppressing factor (dsf) in nc-37 cell infected with measles virus]. | wild strains of measles virus, such as edmonston, toyoshima and freshly isolated km strain which had not a capacity to establish a persistent infection in nc-37 cell inhibited 80-90 percent of host cellular dna synthesis, while attenuated or subacute sclerosing panencephalitis (sspe) viruses, such as schwarz, halle and mantooth which had a capacity to establish persistent infection inhibited about 50 percent of host cellular dna synthesis 6 or 7 days after infection of virus. however, inhibition ... | 1980 | 7239420 |
| characterization of measles virus recovered from persistently infected vero cells. | vero cells were persistently infected with measles virus in medium with antimeasles serum. when antiserum was not added to the medium, the persistently infected cells (vmas cells) proliferated in a cyclical manner alternating between extensive cell destruction and renewed cell growth. when these cells were grown at 33 c and 40 c, they released temperature-sensitive and temperature-dependent viruses. however, these viruses, upon further propagation, reverted to the wild type suggesting that such ... | 1980 | 7265556 |
| complementation analysis of measles virus mutants isolated from persistently infected lymphoblastoid cell lines. | human lymphoblastoid cell lines persistently infected with measles virus release a heterogeneous population of virions. at least 80% of the infectious particles were temperature sensitive for plaque formation at 39 degrees c. plaque-purified temperature-sensitive mutants from four persistently infected human lymphoblastoid cell lines were shown to be heterogeneous with respect to efficiency of plating at 31 and 39 degrees c, as well as to antigen and rna production at 39 degrees c. the heterogen ... | 1980 | 7365873 |
| the glycoprotein of measles virus. external radioactive labelling of its carbohydrate and partial characterization of the glycopeptide. | measles virus was propagated in vero cells and purified from the culture supernatants by two successive tartrate-density-gradient centrifugations. surface carbohydrates were labelled both in vitro and in vivo with 3h after treatment with galactose oxidase/nab3h4 or with [3h]glucosamine. the major labelled glycoprotein in measles virions had a mol.wt. of 79 000. after labelling with periodate/nab3h4, which would result in specific labelling of sialic acid residues, the 79 000-mol.wt. glycoprotein ... | 1980 | 7378046 |
| alterations in expression of measles virus polypeptides by antibody: molecular events in antibody-induced antigenic modulation. | six hours after measles virus antibodies bind to the surface of hela cells acutely infected with measles virus, the expression of an external polypeptide f1, as well as internal polypeptides p and m are altered. the loss of f1 molecules during antibody-induced antigenic modulation explains the lack of cell-cell fusion and giant cell formation of infected cells cultured in the presence of antibody. the decrease in f1, p, and m viral polypeptides is specific, since the effect is only seen with ant ... | 1980 | 7381212 |
| structural phosphoproteins associated with measles virus nucleocapsids from persistently infected cells. | measles virus nucleocapsids were labelled with 3h-amino acids and 32p-orthlls (av+). when analysed by sds-page, the two major capsid-associated polypeptides (p, mol. wt. 69,000, and np, mol. wt. 60,000) were shown to be phosphorylated. subsequent characterization of the phosphorylated polypeptides by acid hydrolysis and high voltage paper electrophoresis showed that serine and threonine were the major phosphorylated amino acid species. the similarities between the peptide phosphorylation pattern ... | 1980 | 7400779 |
| virus infection of endothelial cells increases granulocyte adherence. | adherence of human granulocytes was measured on endothelial monolayers of human and bovine origin, grown in 35-mm diam petri dishes and in cluster wells. adherence to human endothelium in petri dishes using 1.0 ml of whole blood averaged 17.9+/-3.7%, and to bovine endothelium was 20.3+/-3.7%. cluster wells required only 1/5 the endothelial cells needed for petri dishes, and 0.25 ml of whole blood yielded average adherence of 26.2+/-3.4 to human cells and 28.0+/-3.7 to bovine in the wells. the im ... | 1980 | 7410550 |
| intracerebral synthesis of antibodies to measles and distemper viruses in patients with subacute sclerosing panencephalitis and multiple sclerosis. | serum and cerebrospinal fluid (csf) measles and distemper antibody levels were quantified in a series of twenty patients (four subacute sclerosing panencephalitis (sspe); ten multiple sclerosis (ms); six non-ms neurological cases) using independent competitive inhibition radioimmunoassays. these results were used in a tourtellotte calculation to measure the intracerebral igg synthesis to each virus. the results confirmed that in sspe there is a greatly enhanced intracerebral measles antibody syn ... | 1980 | 7389198 |
| [nature of measles virus antibodies in systemic lupus erythematosus]. | 1980 | 7423262 | |
| proliferation of multiple sclerosis cerebrospinal fluid lymphocytes after stimulation with measles virus antigens. | a method for measuring the proliferative response of cerebrospinal fluid (csf) lymphocytes upon stimulation and mitogens and viral antigens has been developed. the number of lymphoid cells in dna synthesis after in vitro stimulation is counted and the results expressed as a percentage of the total number of surviving lymphocytes. preliminary results on four ms patients indicated that their csf lymphocytes responded considerably more strongly to purified measles virus antigen than did correspondi ... | 1980 | 7468152 |
| quantitation of measles-specific igg. its presence in csf and brain extracts of patients with multiple sclerosis. | twenty of 41 patients with multiple sclerosis (ms) and five of 30 patients with other neurological diseases had measles antibody titers in their csf when examined in hemagglutination inhibition and neutralization tests. quantitation of measles-specific igg in csf of patients with ms with significant measles antibody titers showed that less than 5% of the total igg was measles virus specific. in contrast, using the identical quantitation procedures, 30% to 60% of the total igg in csf of patients ... | 1980 | 7425885 |
| role of virus strain in conventional and enhanced measles plaque neutralization test. | a low-passage edmonston strain of measles virus gave on the average four-fold higher antibody titers than two high-passage strains of edmonston virus when used in a virus plaque neutralization test. heterologous anti-human immunoglobulin did not affect antibody titers obtained with the low-passage virus but enhanced antibody titers obtained with the high-passage viruses on the average eight-fold. these differences in virus sensitivity to neutralization and neutralization potentiation by anti-imm ... | 1981 | 7334066 |
| atypical measles syndrome: unusual hepatic, pulmonary, and immunologic aspects. | the atypical measles syndrome is a relatively new disease that was first recognized 15 years ago. initially, it occurred in children who were exposed to wild measles virus several years after they were immunized with killed measles vaccine. it was characterized by a two- to three-day prodrome of high fever, cough, headache, and myalgia followed by a rash that resembled rocky mountain spotted fever, scarlet fever, or varicella and associated with roentgenographic evidence of pneumonia with or wit ... | 1981 | 7468641 |
| selective killing of subacute sclerosing panencephalitis virus-infected cells by liposomes containing fragment a of diphtheria toxin. | 1981 | 7215444 | |
| [revaccination of children inoculated against measles]. | 1981 | 7335425 | |
| the measles virus-specific protein synthesis of persistently and lytically infected cells studied in vivo and in vitro. | the virus-specific protein synthesis of the hamster brain cells persistently infected with a wild-type measles virus (m-mb/mvb) was investigated in vivo and in vitro and compared to the protein synthesis of the vero-cells lytically infected with the wild-type measles virus and the sspe-measles virus strain lec. the virus-specific protein synthesis in the m-hb/mvb-cells in vivo was weak. only two virus-specific polypeptides, corresponding to polypeptide g and nucleocapsid polypeptide np, were det ... | 1981 | 7336924 |
| a radioimmunoassay search for measles and distemper antigens in subacute sclerosing panencephalitis and multiple sclerosis brain tissues. | solid-phase direct sandwich radioimmunoassays have been developed which will detect measles antigen in as little as 20 microgram of sspe brain, measles antigen in 5 x 10(4) pfu/ml of measles virus, and canine distemper antigen in 5 x 10(5) pfu/ml of this virus. using these assays, a search was carried out for measles and distemper antigens in cns autopsy tissue from 3 multiple sclerosis (ms) patients. even in 1000-fol higher concentrations of ms brain (20 mg), antigens of neither virus were dete ... | 1981 | 7276988 |
| a population screening test for antibody to measles virus. | in areas where sporadic cases of measles continue to occur in spite of vaccination programs, the availability of a simple screening test for determination of seropositivity to measles virus is desirable. a sensitive radioimmunoassay (ria) screening test (st) for the detection of igg antibody to measles virus, based on a solid phase ria, is described. the assays were performed on polyvinyl microtiter plates for which the riast requires only 5 microliters of serum per subject. antigen consisted of ... | 1981 | 7319792 |
| structural changes in the cell nucleus during measles virus infection in cerebellar explants. | 1981 | 7321086 | |
| host cell factors involved in the production of slowly sedimenting nucleocapsids in measles virus-infected cells. | a decrease in the sedimentation rates of the measles virus nucleocapsid, and the rna contained within, were observed during acute measles virus infection when the growth conditions of vero cells were altered. the change in sedimentation rates of virus nucleocapsids in these experiments was apparently due to the physiological state of the cell and was independent of the history of the measles virus used for infection since: (i) the same virus stock was used to infect cells from which nucleocapsid ... | 1981 | 7218422 |
| measles virus polypeptides in infected cells studied by immune precipitation and one-dimensional peptide mapping. | measles virus does not turn off host cell polypeptide synthesis, making it difficult to precisely identify the polypeptides specified by the virus during the infectious cycle. by using the technique of immune precipitation with measles-specific antisera, the host cell background has been eliminated, and new observations have been made concerning measles virus polypeptides h, p, np, f, and m. the h polypeptide is first synthesized as a monomer which is processed by further glycosylation and by th ... | 1981 | 7241653 |
| [measles virus antibodies and cerebrospinal fluid and serum proteins in selected chronic diseases of the central nervous system in children]. | 1981 | 7254961 | |
| measles virus and chronic neurological diseases. | 1981 | 7212662 | |
| encephalitis after inhalation of measles virus: a pathogenetic study in hamsters. | a neuroadapted strain of measles virus (hnt) was administered by inhalation to newborn hamsters. primary replication of virus in the lung was followed by the transient appearance of virus in spleen within 7 to 9 days of inoculation. a terminal encephalitis occurred between 6 and 60 days in 31% of infected hamsters, and virus was recovered by explant culture of these brains. virus could not be cultured directly from brain or tissue homogenates. at least 7% of hamsters that had survived the infect ... | 1981 | 7212663 |
| development of antiviral levels of ribavirin in serum and urine of orally treated rats. | the levels of ribavirin or its antivirally active metabolic products were determined in the serum and urine of rats treated with single oral doses of 1,000 or 100 mg/kg of the compound, using a newly developed micromethod in which measles virus inhibition was assayed in bs-c-1 cells. at the high dosage level, maximum ribavirin serum levels of 24 microgram/ml were observed 2 h postribavirin administration. approximately 10-fold less active material was seen in the rats receiving the lower ribavir ... | 1981 | 7215001 |
| the replication of measles virus in the presence of tunicamycin. | 1981 | 7467126 | |
| cells infected with a cell-associated subacute sclerosing panencephalitis virus do not express m protein. | 1981 | 7467128 | |
| immunologic and virologic studies of measles inclusion body encephalitis in an immunosuppressed host: the relationship to subacute sclerosing panencephalitis. | an immunosuppressed child with acute lymphoblastic leukemia in clinical remission developed measles inclusion body encephalitis (mibe). although measles antigen and nonbudding measles virus nucleocapsids were detected in brain tissue, no virus was isolated. immune precipitation of measles virus proteins with the patient's serum showed no detectable antibody to virus m protein, a finding that has been reported in subacute sclerosing panencephalitis (sspe). the virologic and immune precipitation s ... | 1981 | 7202137 |
| antibodies to viral and non-viral antigens in subacute sclerosing panencephalitis and multiple sclerosis demonstrated by thin-layer polyacrylamide gel isoelectric focusing, antigen immunofixation and autoradiography. | antibody activity in igg zones separated by thin-layer polyacrylamide gel isoelectric focusing (pag ief) was determined in 3 patients with subacute sclerosing panencephalitis (sspe), 4 patients with multiple sclerosis (ms) and 4 subjects with psychosomatic disorders, using antigen immunofixation and autoradiography. viral (measles herpes simplex type 1, mumps) and non-viral (purified bovine myelin, bovine myelin basic protein, bovine oligodendrocytes, ms and normal human brain extract) were used ... | 1981 | 7205324 |
| measles and canine distemper antibody. presence in sera from patients with multiple sclerosis and matched control subjects. | antibody to measles virus and canine distemper virus (cdv) was demonstrated in sera from patients with multiple sclerosis (ms) and from carefully matched control subjects. elevated measles and cdv antibody titers were found in patients with ms when compared with the matched control subjects. the correlation between the measles and cdv antibody titers was quite high, suggesting that the antibody levels between the two viruses are very closely related. based on the results of our study and a revie ... | 1981 | 7458716 |
| lymphoid cell infection by measles virus in newborn hamsters. role for monocytes in virus spread to distant sites. | following intraperitoneal inoculation of measles (hbs) virus into newborn hamsters widespread but variable productive lymphoid tissue infection was detected by a sensitive viral isolation technique. peritoneal wash cells and spleen were the most common sites of infection. virus was frequently isolated from the bone marrow and was commonly found in multiple lymph nodes. thymic infection was only rarely demonstrated. a mononuclear cell associated viremia was demonstrated by ficollhypaque fractiona ... | 1981 | 7334082 |
| antibody response to structural proteins of measles virus in patients with natural measles and subacute sclerosing panencephalitis. | by immunoprecipitation and sds-polyacrylamide gel electrophoresis, antibody responses to the structural proteins of measles virus were examined on patients with various forms of natural measles, atypical measles, and subacute sclerosing panencephalitis (sspe). the serum of atypical measles most strongly reacted with four structural proteins, i.e., hemagglutinin (h), nucleocapsid (nc), fusion (f), and matrix (m) proteins. in natural measles, antibodies to the four structural proteins were detecte ... | 1981 | 7334708 |
| [production of antibodies against measles virus and hbs antigen by use of the mouse hybridoma technique (author's transl)]. | 1981 | 7336577 | |
| coronavirus antibodies in patients with multiple sclerosis. | 1981 | 7337041 | |
| an extremely attenuated, live measles virus vaccine (cam-ex). persistence of low titer-antibody in institutionalized children with psychomotor retardation after vaccination. | fifty children with psychomotor retardation, who had no detectable measles hemagglutination-inhibition (hi) antibody, were vaccinated with an extremely attenuated, live measles virus vaccine (cam-ex). only 10% of the children had fever after vaccination. no other symptoms were observed. forty of 44 vaccinated children showed increase in hi antibody titers of 2(3) or more, with a geometric mean titer of 2(4.2). a five-year follow-up study revealed that the initially low-titer antibodies persisted ... | 1981 | 7337678 |
| [measles and titers of measles antibodies in the cerebrospinal fluid and blood in children with chronic diseases of the central nervous system]. | 1981 | 7339556 | |
| measles virus antibodies in a laboratory colony of owl monkeys (aotus trivirgatus). | serologic testing revealed that 17/84 (20.2%) of bought-in aotus and 1/31 (3.2%) of colony-born aotus had haemagglutination-inhibition antibody. clinically-inapparent measles infections were detected in 3 monkeys by increased antibody titres. following the detection of a recent infection, antibody titre persisted at a high level for at least 240 days. although 84% of the monkeys were sero-susceptible, no further serological evidence of measles infection occurred. | 1981 | 7341843 |
| optimal age for vaccinating nigerian children against measles. i. neonatal antibody profile and subsequent susceptibility to measles. | the decline of maternally acquired haemagglutination inhibiting antibodies against measles virus in nigerian children born in lagos was studied. at birth all the 303 children whose cord blood serum was tested had measurable antibodies. the antibody titre remained detectable in all the children up to four months of age, and in over 90% at five months of age. at six months 65% of the children were without detectable antibodies. at seven and eight months the proportion of children without measurabl ... | 1981 | 7342384 |
| optimal age for vaccinating nigerian children against measles. ii. seroconversion to measles vaccine in different age groups. | ninety-eight children between five and nine months were given measles vaccine. bloodsamples were taken before and again six to eight weeks after immunization and tested for haemagglutination inhibition antibodies to measles virus. it was found that the sero-conversion rate was significantly lower (p less than 0.05) in infants under seven months than over this age. the results suggest that although some immunized at six months of age show seroconversion, the proportion is too small to justify ext ... | 1981 | 7342385 |
| [an immunocytochemical study on measles virus infection of the central nervous system]. | 1981 | 7347454 | |
| [immunologic evaluation of measles vaccine in preschool and school children]. | 1981 | 7347862 | |
| [clinico-immunological indicators in patients with measles in focal infection]. | 1981 | 7332656 | |
| antibodies against measles virus polypeptides in different disease conditions. | the occurrence of antibodies to the nucleoprotein and matrix (m) antigens of measles virus was determined in early and late measles convalescent sera and in sera from patients with multiple sclerosis, subacute sclerosing panencephalitis, chronic active hepatitis, and atypical measles. antibodies to the two components were identified separately in serially diluted samples both by radioimmune precipitation assays and by complement fixation tests employing purified nucleoprotein and m components as ... | 1981 | 7333668 |
| evolution of a human cell line persistently infected with measles virus. | a measles-virus-carrier cell line, designated av3/mv, was derived from established human amnion (av3) cells surviving primary infection with the edmonston strain of measles virus. during maintenance of infected cultures in the laboratory, the cells passed from a highly productive chronic phase (where infectious virus was continuously shed) to a less productive degenerative phase (where fewer infectious particles were produced). carrier cultures in the less-productive phase gradually deteriorated ... | 1981 | 7333792 |
| acute viral infection of the central nervous system in children: an 8-year review. | reliable information on acute viral infections of the central nervous system (cns) in canadian children has not been available. to investigation this disease in halifax the medical records of 180 patients with presumed or definite acute viral cns infection diagnosed at the izaak walton killam hospital for children over an 8-year period were reviewed. the yearly incidence was estimated at 19.5/100 000 for children up to 16 years of age, and the peak incidence was in july, august and september. th ... | 1981 | 7284937 |
| purification of measles virus glycoproteins and their integration into artificial lipid membranes. | we report a simple method for the isolation of the measles virus glycoproteins, and their subsequent incorporation into artificial lipid bilayers. the two viral glycoproteins, ha and f, were isolated in preparative amounts from disrupted purified virus by lentil lectin affinity chromatography. the proteins were reconstituted into single bilayer lipid vesicles by: (i) exchanging the non-dialysable detergent nonidet p40 (np40) for a dialysable one, octylglucoside, while the proteins were immobiliz ... | 1981 | 7288404 |
| monoclonal antibodies against measles virus. | monoclonal antibodies were produced in vitro by fusing mouse myeloma cells (sp2) with spleen cells derived from balb/c mice immunized with purified measles virus. fifteen independent hybrid cell lines, isolated from two separate fusions, were maintained in culture for up to 5 months without loss of their antibody-secreting activity. radioimmunoprecipitation and polyacrylamide gel electrophoresis showed that in five of the hybrid lines the antibodies were directed against haemagglutinin, in two a ... | 1981 | 7288410 |
| persistent measles virus infection of a clonal line of neuroblastoma: effect on neural differentiation. | 1981 | 7321772 | |
| rna and dna viral stimulation of prostaglandin e production by human synovial fibroblasts. | 1981 | 7326073 |