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abscess-forming lymphadenopathy and osteomyelitis in children with bartonella henselae infection.bartonella henselae is the agent of cat-scratch disease (csd), a chronic lymphadenopathy among children and adolescents. a systemic infection is very rare and most of these cases are found in patients with immunodeficiency. here, cases involving four children of 6-12 years of age are reported. three of the children had an abscess-forming lymphadenopathy and surrounding myositis in the clavicular region of the upper arm. the diagnosis was made serologically and, in one case, using eubacterial uni ...200818349375
molecular characterization of bartonella vinsonii subsp. berkhoffii genotype iii.the molecular characterization of a bartonella vinsonii subsp. berkhoffii genotype iii strain (ncsu strain 06-co1) isolated from the blood of a military working dog diagnosed with endocarditis is reported in this study. several genes were amplified and sequenced for comparative sequence similarity with other strains.200818367567
[a high prevalence of antibodies against bartonella and babesia microti has been found in villages and urban populations in cordoba, colombia].establishing seroprevalence against bartonella and babesia microti in arural population exposed and/or non-exposed to domestic animals in cordoba,colombia.200818368229
prolonged bartonella henselae bacteremia caused by reinfection in cats.we analyzed the genetic relatedness of blood culture isolates of bartonella henselae from 2 cats of patients with cat-scratch disease at admission and after 12 months. isolates from each cat at different times were clonally unrelated, which suggested reinfection by a second strain.200818258096
[ocular bartonellosis: report of three clinical cases].the characteristic clinical presentation of cat scratch disease is subacute regional lymphadenopathy; nevertheless, 5-25% of bartonella henselae infections may present an atypical or systemic form, with potential eye involvement. we describe three clinical cases of ocular bartonellosis in two adolescents and one young adult, who had close contact with cats; all of them presented persistent fever ranging from 15 to 21 days, and two of them developed a sudden unilateral loss of visual acuity assoc ...200818273527
detection of two bartonella tamiae-like sequences in amblyomma americanum (acari: ixodidae) using 16s-23s intergenic spacer region-specific primers.four hundred and sixty-six questing amblyomma americanum (l.) (acari: ixodidae) from carolina county, va, and 98 questing a. americanum from chatham county, nc, were screened by polymerase chain reaction (pcr) for the bartonella 16s-23s intergenic spacer region. two amplicons, approximately 270-280 bp, were detected in two ticks from virginia. based upon pcr and sequencing, an adult male and adult female tick harbored dna sequences closely related to bartonella tamiae (dq395180). bartonella dna ...200818283962
infectious diseases of dogs and cats on isabela island, galapagos.vaccination and importation of dogs and cats are prohibited in the galapagos, resulting in a uniquely isolated population. the purpose of this study was to determine the prevalence of infectious diseases of dogs and cats that impact their health, could spill over to native wildlife, or sentinel diseases of concern to humans.200818289290
bartonella dna in the blood and lymph nodes of golden retrievers with lymphoma and in healthy controls.although lymphoma is the most common neoplastic process reported in dogs, its precise etiology is unknown. golden retrievers are more likely to develop lymphoma, suggesting a breed predisposition; however, other factors, including environment, immunity, and infection, are likely contributors to oncogenesis.200818289294
lymphadenopathy in a novel mouse model of bartonella-induced cat scratch disease results from lymphocyte immigration and proliferation and is regulated by interferon-alpha/beta.in immunocompetent humans, cat scratch disease (csd) is elicited by the gram-negative bacterium bartonella henselae and is characterized by a benign regional lymphadenopathy, the pathogenesis of which is poorly understood. here, we describe a novel mouse model of bartonella-induced csd-like disease that allowed us to investigate the mechanisms leading to lymphadenopathy in vivo. in wild-type mice, a subcutaneous inoculation of either viable or inactivated b. henselae led to a strong swelling of ...200818292236
serological evidence of bartonella henselae infection in healthy people in catalonia, spain.cat scratch disease (csd), bacillary angiomatosis, hepatic peliosis and some cases of bacteraemia, endocarditis, and osteomyelitis are directly caused by some species of the genus bartonella. the purpose of this study was to determine the prevalence of igg antibodies against bartonella henselae in healthy people and to identify the epidemiological factors involved. serum samples from 218 patients were examined by indirect immunofluorescence assay (ifa). significance levels for univariate statist ...200818294428
feline bartonellosis and cat scratch disease.bartonella species are important emerging zoonotic pathogens. transmission of these organisms in nature may be much more complex than is currently appreciated. cats can be infected with five bartonella species, including, bartonella henselae, bartonella clarridgeae, bartonella bovis, bartonella koehlerae and bartonella quintana. in addition to cats, numerous domestic and wild animals, including bovine, canine, human, and rodent species can serve as chronically infected reservoir hosts for variou ...200818295347
detection of bartonella bovis in a cattle herd in italy. 200818192660
bacterial communities of bartonella-positive fleas: diversity and community assembly patterns.we investigated the bacterial communities of nine bartonella-positive fleas (n = 6 oropsylla hirsuta fleas and n = 3 oropsylla montana fleas), using universal primers, clone libraries, and dna sequencing. dna sequences were used to classify bacteria detected in a phylogenetic context, to explore community assembly patterns within individual fleas, and to survey diversity patterns in dominant lineages.200818203862
ciclosporin-induced fibrovascular polyps vs. bacillary angiomatosis. 200818205872
hepatosplenic cat-scratch fever. 200818222165
genetic diversity and phylogenetic relationships of bacteria belonging to the ochrobactrum-brucella group by reca and 16s rrna gene-based comparative sequence analysis.the genetic diversity and phylogenetic interrelationships among 106 ochrobactrum strains (o. anthropi: 72, o. intermedium: 22, o. tritici: 5, o. oryzae: 2, o. grignonense: 2, o. gallinifaecis: 1, o. lupini: 2), the type strains of the eight brucella species and other closely related taxa were studied by reca and rrs gene (16s rrna) comparative sequence analysis. both markers correctly delineated the various ochrobactrum species; however, resolution at the subspecies level was considerably higher ...200818222618
characterization of bartonella strains isolated from black-tailed prairie dogs (cynomys ludovicianus).thirty bartonella strains were isolated from the blood of black-tailed prairie dogs (cynomys ludovicianus) from boulder county, colorado, usa. the bacteria appeared as small, fastidious, aerobic, gram-negative rods. the partial sequences of the citrate synthase gene (glta) demonstrated five unique genetic variants. phylogenetic analysis based on sequences of glta, 16s rrna, rpob, ftsz, and ribc showed that the black-tailed prairie dog-related bartonella variants comprise a distinct monophyletic ...200818237261
attention: attention-deficit/ hyperactivity disorder. 200818240846
temporal and spatial patterns of bartonella infection in black-tailed prairie dogs (cynomys ludovicianus).we describe the temporal dynamics and spatial distribution of bartonella in black-tailed prairie dogs (cynomys ludovicianus) based on a longitudinal study conducted in 20 black-tailed prairie dog (btpd) colonies in boulder county, co from 2003 to 2005. bartonella infection was widely distributed in all colonies with an overall prevalence of 23.1%, but varied by colony from 4.8% to 42.5% and by year from 9.1 to 39.0%, with a marked increase in bartonella activity in 2005. levels of bacteremia var ...200818176820
[stellar neuroretinitis and bartonella henselae infection. a case report without exposure to cats]. 200818187281
isolation and characterization of bartonella bacilliformis from an expatriate ecuadorian.carrion's disease is typically biphasic with acute febrile illness characterized by bacteremia and severe hemolytic anemia (oroya fever), followed by benign, chronic cutaneous lesions (verruga peruana). the causative agent, bartonella bacilliformis, is endemic in specific regions of peru and ecuador. we describe atypical infection in an expatriate patient who presented with acute splenomegaly and anemia 3 years after visiting ecuador. initial serology and pcr of the patient's blood and serum wer ...200818094131
molecular method for bartonella species identification in clinical and environmental samples.a new, efficient molecular method for detection of bartonella, based on the 16s-23s rrna intergenic spacer and 16s rrna amplification by multiplex pcr combined with reverse line blotting, was designed. this assay could simultaneously detect 20 different known species and other bartonella species not described previously.200818094134
diversifying selection and concerted evolution of a type iv secretion system in bartonella.we have studied the evolution of a type iv secretion system (t4ss), in bartonella, which is thought to have changed function from conjugation to erythrocyte adherence following a recent horizontal gene transfer event. the system, called trw, is unique among t4sss in that genes encoding both exo- and intracellular components are located within the same duplicated fragment. this provides an opportunity to study the influence of selection on proteins involved in host-pathogen interactions. we seque ...200818065487
pcr for bacterial 16s ribosomal dna in multiple sclerosis cerebrospinal fluid.the cause of multiple sclerosis (ms) is currently unknown. the hypothesis of this study is that ms is caused by a chronic bacterial infection of the central nervous system (cns) and the ensuing immune response. we developed a sensitive two-stage polymerase chain reaction method using nested or semi-nested primers specific for the bacterial 16s ribosomal dna to test for the presence of bacterial dna in cerebrospinal fluid. we designed seven sets of primers to amplify dna from spirochetes , campyl ...200817986505
a sacb mutagenesis strategy reveals that the bartonella quintana variably expressed outer membrane proteins are required for bloodstream infection of the host.bartonella bacteria adhere to erythrocytes and persistently infect the mammalian bloodstream. we previously identified four highly conserved bartonella quintana adhesin genes that undergo phase variation during prolonged bloodstream infection. the variably expressed outer membrane proteins (vomp) encoded by these genes are members of the trimeric autotransporter adhesin family. each b. quintana vomp appears to contribute a different adhesion phenotype, likely mediated by the major variable regio ...200818070893
bartonella tamiae sp. nov., a newly recognized pathogen isolated from three human patients from thailand.three strains of a novel bartonella species (bartonella tamiae) were isolated from human patients from thailand. sequence analysis of six chromosomal regions (16s rrna, glta, groel, ftsz, rpob, and the intergenic spacer region) and phenotypical analysis supported the similarity of the three strains and placed them within the genus bartonella separately from previously described species.200818077632
vector-borne infections in cats: molecular study in barcelona area (spain).previous serological surveys have reported the presence of different organisms in cats from spain but little reports exist about the exact identity of these organisms. the purpose of the study reported here was to assess the presence of dna of several vector-borne infections in a population of cats from barcelona area. one hundred blood samples obtained from cats admitted to the uab-vth were entered into the study and classified as healthy (n=48) or unhealthy (n=52). edta-blood samples were assa ...200818079064
discovery and analysis of bartonella henselae antigens for use in clinical serologic assays.the antibody response to bartonella henselae has been studied in a number of mammals; however, the human response needs to be further studied. after natural infection, humans have antibody reactivity to a large number of b. henselae proteins. we used a proteomic approach to identify antigenic proteins of b. henselae to determine their capacity to elicit a human antibody response. comparing patient sera by western blot analysis demonstrated significant amounts of reactivity to b. henselae. the im ...200817889484
a view on bartonella quintana endocarditis--confirming the molecular diagnosis by specific fluorescence in situ hybridization.culture-negative endocarditis is a frequent problem in cardiology, especially if caused by fastidious organisms. among these, the diagnostic tools for the detection of bartonella quintana are still unsatisfactory. in a culture-negative case of suspected endocarditis undergoing aortic valve replacement, polymerase chain reaction amplification and sequencing of the 16s rrna gene indicated b. quintana infection. to develop a new diagnostic tool, independent from culture and amplification techniques ...200817889492
evaluation of the association of bartonella species, feline herpesvirus 1, feline calicivirus, feline leukemia virus and feline immunodeficiency virus with chronic feline gingivostomatitis.gingivostomatitis (gs) is a significant condition in cats because of oral discomfort and associated periodontal disease. several infectious agents have been associated with the presence of gs, but a causal relationship is unclear. the cats in this study were housed together, had a history of flea exposure, and were vaccinated with a modified live fvrcp product. there were nine cats with active gs and 36 unaffected cats at the time of sample collection. serum was tested for feline leukemia virus ...200817766156
prevalence of ehrlichia canis, anaplasma platys, babesia canis vogeli, hepatozoon canis, bartonella vinsonii berkhoffii, and rickettsia spp. in dogs from grenada.to identify the tick-borne pathogens in dogs from grenada, we conducted a serologic survey for ehrlichia canis in 2004 (104 dogs) and a comprehensive serologic and molecular survey for a variety of tick-borne pathogens in 2006 (73 dogs). in 2004 and 2006, 44 and 32 dogs (42.3% and 43.8%) were seropositive for e. canis, respectively. in 2006, several tick-borne pathogens were identified by serology and pcr. dna of e. canis, anaplasma platys, babesia canis vogeli, hepatozoon canis, and bartonella ...200818160223
bacillary angiomatosis in a patient with chronic lymphocytic leukemia.bacillary angiomatosis is a cutaneous or visceral infection with bartonella henselae or bartonella quintana. cases usually occur in hiv infected individuals. we present a 60-year-old man with chronic lymphocytic leukemia and neutropenic fever caused by bacillary angiomatosis. the nine ba cases in oncology patients are reviewed.200818165862
bartonella henselae lymphadenitis progressing to hepatosplenic disease with slow clinical response despite early diagnosis and treatment. 200817343673
prolonged follow up of seven patients affected by hepatosplenic granulomata due to cat-scratch disease.this study is a retrospective analysis of seven patients with hypoechogenic lesions in the liver and/or spleen due to bartonella henselae, who were followed from 1998 through to 2005 by the department of pediatrics, turin university. in addition to showing constitutional symptoms, four children had skin lesions suggestive of injuries inflicted by cats, and one child had a history of exposure to cats. the origin of the infection remained undefined in the other two patients. humoral tests enabled ...200817541640
high bartonella spp. seroprevalence in a swedish homeless population but no evidence of trench fever.blood samples and epidemiological data were collected from 50 homeless patients in central stockholm, sweden. sera were analysed for antibodies to b. henselae, b. quintana, b. elizabethae and b. grahamii. whole blood was cultured and used as substrate for a newly developed quantitative real time polymerase chain reaction (qpcr) specifically targeting bartonella spp. dna. 61 matched blood donor sera were used as controls. homeless patients were significantly more often seropositive to bartonella ...200817852922
[painful soft-tissue swelling of the upper arm].cat-scratch disease is an infection by bartonella henselea and resolves spontaneously. we present a case of untypical bartonella infection which was misinterpreted by mri as a soft-tissue sarcoma of the upper arm. the histological findings of an incision biopsy were unspecific, without signs of malignancy. the tumor was excised completely and the final histology, however, showed no evidence of malignant changes. the bartonella henselae infection could be confirmed by polymerase chain reaction. t ...200817443304
prevalence of serum antibodies against bartonella species in the serum of cats with or without uveitis.bartonella henselae has been implicated as a causative agent of chronic uveitis in people and in some cats. the objective of this study was to determine whether bartonella species seroprevalence or titer magnitude varies among cats with uveitis, cats without ocular diseases recorded and healthy cats, while controlling for age and risk of flea exposure based on state of residence. there was no difference in seroprevalence rates or titer magnitude between cats with uveitis and cats with non-ocular ...200817719256
bartonella: emerging pathogen or emerging awareness?the number of known bartonella species is rapidly growing. some of them are responsible for distinct infectious diseases and show different prevalence and antibiotic susceptibility profiles. not only have some vectors of bartonella not been fully characterized, but also intermediate hosts are actually much more numerous and diverse than previously thought. among these, dogs differ from cats because they tend to suffer an overt disease similar to humans, thus providing the base for a useful anima ...200918621561
color doppler pseudolymphomatous manifestations of the cat scratch disease.cat scratch disease (csd) is an infectious illness, caused by the bartonella henselae bacterium. besides the common infective symptoms, swelling in the axillary and cervical region is very common and is usually evaluated by color doppler us (cdus) (among other diagnostic methods). the aim of this work is to present ultrasound findings of the cat scratch disease. during 2002 and 2003, we followed four patients (three male and one female) by cdus, with different manifestations of the disease. the ...200920380135
serous labyrinthitis as a manifestation of cat scratch disease: a case report.abstract : introduction : cat scratch disease is an infectious disease transmitted by young cats, in which the principal causative factor is bartonella henselae. the typical course of cat scratch disease is usually benign and self-limited and requires only supportive therapy. however, cases lasting up to 2 years have been reported, and more serious complications may occur. many manifestations of the disease have been reported by different medical disciplines. case presentation : a case of cat sc ...200920519021
molecular mechanism of gentamicin resistance in bartonella henselae. 200920584166
localised retinal vasculitis in cat scratch disease.we report an atypical presentation of ocular cat scratch disease (csd) in an 8-year-old caucasian male who presented with localised retinal arterial vasculitis and associated retinal oedema. his history of headaches, frequent contact with a kitten and a high bartonella henslelae titre confirmed the diagnosis of csd. over an 18-month follow-up period, his best corrected visual acuity in the affected eye improved from 20/30-2 to 20/25+3 without treatment; however, the affected retinal artery remai ...200921686569
bartonella endocarditis complicating congenital heart disease.the present report describes a case of bartonella henselae endocarditis affecting an adolescent with congenital heart disease. a teenager from eastern europe was referred to for surgical treatment of aortic endocarditis. she admitted close contact with cats. blood culture was negative. diagnosis of b henselae was established on direct pcr amplification and 16srrna gene sequencing of the aortic valve tissue and confirmed after 4 weeks by valve culture isolate. the patient underwent extended root ...200921686936
pcr detection of bartonella bovis and bartonella henselae in the blood of beef cattle.although an organism primarily associated with non-clinical bacteremia in domestic cattle and wild ruminants, bartonella bovis was recently defined as a cause of bovine endocarditis. the purpose of this study was to develop a b. bovis species-specific pcr assay that could be used to confirm the molecular prevalence of bartonella spp. infection. blood samples from 142 cattle were tested by conventional pcr targeting the bartonella 16s-23s intergenic spacer (its) region. overall, bartonella dna wa ...200919019574
cervical lymphadenopathy in childhood epidemiology and management.cervical lymphadenopathy (cl) is common in childhood. the aim of this study is to evaluate the etiology, follow-up, and treatment of persistent cl. the authors studied retrospectively 50 children with cl, hospitalized at the department of pediatrics and pediatrics surgery. patients underwent ultrasonography. thirty-six percent presented abnormal ultrasonographic image and underwent excisional biopsy. biopsies revealed 4 thyroglossal cysts, 3 branchial cysts, 1 hemangioma, 2 sebaceous cysts, 1 de ...200919657996
pestilence, persistence and pathogenicity: infection strategies of bartonella.it has been nearly two decades since the discovery of bartonella as an agent of bacillary angiomatosis in aids patients and persistent bacteremia and 'nonculturable' endocarditis in homeless people. since that time, the number of bartonella species identified has increased from one to 24, and 10 of these bacteria are associated with human disease. although bartonella is the only genus that infects human erythrocytes and triggers pathological angiogenesis in the vascular bed, the group remains un ...200919659429
[cat scratch disease--a diagnostic problem, case report].cat scratch disease as a possible cause of neck limphadenopathy.200919681487
real-time pcr strategy and detection of bacterial agents of lymphadenitis.the aim of this study was to compare 16 s rrna gene amplification and sequencing with a systematic real-time pcr assay screening strategy that includes all common known pathogens recovered from lymph node biopsy specimens. lymph node biopsy samples sent to our laboratory from january 2007 to december 2008 were tested in the study. lymph nodes were screened for the presence of any bacteria by pcr amplification and sequencing targeting the 16 s rrna gene and also by a specific real-time pcr strate ...200919685089
genomics of host-restricted pathogens of the genus bartonella.the alpha-proteobacterial genus bartonella comprises numerous arthropod-borne pathogens that share a common host-restricted life-style, which is characterized by long-lasting intraerythrocytic infections in their specific mammalian reservoirs and transmission by blood-sucking arthropods. infection of an incidental host (e.g. humans by a zoonotic species) may cause disease in the absence of intra-erythrocytic infection. the genome sequences of four bartonella species are known, i.e. those of the ...200919696500
recurrent osteomyelitis in a cat due to infection with bartonella vinsonii subsp. berkhoffii genotype ii. 200919709358
bartonellosis as cause of death after red blood cell unit transfusion.the authors present the case of a young man with aplastic anemia who went into shock and died after several red blood cell unit transfusions. immunohematological studies did not show any abnormality and blood cultures from patients and blood bags were negative. the ultrastructural findings, allied with current scientific knowledge, permitted the diagnosis of bartonella sp. infection. in face of this diagnosis, two possibilities should be considered: the first one is that the patient was already ...200919728230
[neuroretinitis. clinical cases].evaluate the etiology and the most frequent funduscopic alterations of the neuroretinitis.200919728239
guidelines for the prevention and treatment of opportunistic infections among hiv-exposed and hiv-infected children: recommendations from cdc, the national institutes of health, the hiv medicine association of the infectious diseases society of america, the pediatric infectious diseases society, and the american academy of pediatrics.this report updates and combines into one document earlier versions of guidelines for preventing and treating opportunistic infections (ois) among hiv-exposed and hiv-infected children, last published in 2002 and 2004, respectively. these guidelines are intended for use by clinicians and other health-care workers providing medical care for hiv-exposed and hiv-infected children in the united states. the guidelines discuss opportunistic pathogens that occur in the united states and one that might ...200919730409
culture negative endocarditis caused by bartonella henselae in a child with congenital heart disease.a 9-year-old white male with congenital aortic and subaortic stenosis palliated by the ross-konno procedure presented with culture-negative endocarditis. serologic studies and polymerase chain reaction testing of resected homograft valvular tissue provided evidence of bartonella henselae as the etiology. b. henselae can cause endocarditis in children, particularly those with underlying valvular disease. serologic testing for b. henselae should be considered in children with culture-negative endo ...200919738506
comparative in vivo adulticidal activity of a topical dinotefuran versus an imidacloprid-based formulation against cat fleas (ctenocephalides felis) on cats.fleas cause significant discomfort to pet cats and distress to their owners and are also vectors of disease severe infestations can cause anemia or flea allergy dermatitis and can lead to infections with dipylidium caninum and bartonella henselae. rapid flea kill is an important feature of flea preventives. the efficacy of dinotefuran (vectra for cats and kittens, summit vetpharm) was compared with that of imidacloprid (advantage, bayer animal health) against ctenocephalides felis when applied t ...200919742443
rapid detection of bartonella henselae heat shock protein dna by nested polymerase chain reaction from swollen lymph nodes of a patient with cat-scratch disease. 200919785710
detection of bartonella henselae--dna in macronodular hepatic lesions of an immunocompetent woman. 200919793123
prevalence of coxiella burnetii and bartonella species as cases of infective endocarditis in marseilles (1994-2007). 200919793124
comparison of the performances of mlva vs. the main other typing techniques for bartonella henselae. 200919793125
molecular detection of bartonella quintana in human body lice from mexico city. 200919793127
pcr survey of vectorborne pathogens in dogs living in and around barcelona, an area endemic for leishmaniasis.blood samples from 153 dogs living in and around barcelona were assayed for leishmania infantum and ehrlichia, anaplasma, rickettsia, bartonella, hepatozoon, babesia and theileria species by pcr amplification of dna, and the amplicons obtained were sequenced. the prevalence of the infectious agents was l infantum (29.4 per cent), ehrlichia and anaplasma species (4.0 per cent), hepatozoon canis (3.3 per cent), babesia canis vogeli (2.0 per cent), babesia gibsoni (2.0 per cent), babesia canis cani ...200919168881
delayed exposure to infections and childhood lymphomas: a case-control study.delayed exposure to common infections during childhood, have been implied to cause strong immunological response to a single infectious agent that eventually triggers leukemogenesis. the aim of the present study was to investigate whether decreased exposure to infections, as reflected in a more seronegative spectrum to several common infectious agents, is associated with increased risk for the development of childhood lymphomas.200919169895
isolation or molecular detection of bartonella henselae and bartonella vinsonii subsp. berkhoffii from dogs with idiopathic cavitary effusions. 200919175739
back pain in a child caused by cat scratch disease. 200919209087
[biological and molecular characteristics of a cat-borne bartonella clarridgeiae].to characterize a bartonella strain m9hn-shq from a blood culture of cat from henan province,china.200919621628
bartonella rochalimae and other bartonella spp. in fleas, chile. 200919624952
cat scratch disease: a diagnostic conundrum.we report the case of a patient who presented to a clinic for evaluation of inguinal lymphadenopathy. histology of the lymph nodes revealed micoabscess formation suggesting infection with lymphogranuloma venereum (lgv) or bartonella henselae--the causative agent in cat scratch disease (csd). the patient recalled no preceding animal exposure. clinical and serological findings initially suggested early lgv but convalescent serology supported csd. this serves as an important reminder that b. hensel ...200919625597
bartonella rattaustraliani sp. nov., bartonella queenslandensis sp. nov. and bartonella coopersplainsensis sp. nov., identified in australian rats.a total of 11 bartonella isolates were recovered from the blood of melomys, uromys and rattus species in australia and were characterized using phenotypic and genotypic methods. comparison of 16s rrna gene, ftsz, glta and 16s-23s rrna internal transcribed spacer region sequences from the isolates indicated that they formed three sequence similarity groups that were distinct from one another and from the currently recognized bartonella species. phylogenetic analysis based on alignment of concaten ...200919628592
diffusion-weighted magnetic resonance imaging in cervical lymphadenopathy: report of three cases of patients with bartonella henselae infection mimicking malignant disease.diffusion-weighted mr imaging is a potential technique for differentiation between benign and malignant lymph nodes. however, lympadenopathy caused by bartonella henselae infection showes low adc values in diffusion weighted mri as typically seen in malignant disease.200919636985
cat scratch disease with cervical vertebral osteomyelitis and spinal epidural abscess.cat scratch disease has variable clinical presentations and should be considered in the differential diagnosis of vertebral osteomyelitis and epidural abscess if there is a history of contact with cats. we report a 5-year-old boy with cat scratch disease who presented with painful torticollis and osteomyelitis of the cervical spine associated with an epidural abscess.200919654566
bartonella as a cause of blood culture-negative endocarditis. description of five cases.there is evidence that bartonella is an etiologic factor in human endocarditis. the objective of this article was to describe cases of endocarditis due to bartonella observed at a tertiary-care hospital during 1995-2006. overall, 140 cases of infective endocarditis were seen, of which 10 were blood culture-negative endocarditis, with five being due to bartonella. in four cases, there had been contact with cats. only two patients had pre-existing cardiac valvular disease. three had extracardiac d ...200919480767
immunogenicity of bartonella henselae p26 in cats.cat scratch disease (csd) has an estimated prevalence of approximately 200,000 persons in the usa, and approximately 22,000 new cases occur annually. cats are the natural carriers of bartonella henselae, the agent for csd. zoonotic transmission of b. henselae can result in csd in immunocompetent humans and bacillary angiomatosis in immunosuppressed humans. infection in cats often goes undetected. development of a vaccine to prevent feline infection is warranted to reduce the prevalence of infect ...200919500857
[current state of the knowledge of bartonella infections].bartonella spp. are gram-negative bacteria localized in erythrocytes of vertebrate hosts. genus bartonella contains numerous recently described species, many of them are new and emerging arthropod-borne human pathogens. in addition to humans, bartonella spp. have also been isolated from a variety of domesticated (cats, dogs) and wild animals (carnivores, ruminants, rodents), which play a key role as reservoir hosts for these pathogens. the infectious process and the pathogenesis of bartonellosis ...200919522219
bartonella quintana in body lice and head lice from homeless persons, san francisco, california, usa.bartonella quintana is a bacterium that causes trench fever in humans. past reports have shown bartonella spp. infections in homeless populations in san francisco, california, usa. the california department of public health in collaboration with san francisco project homeless connect initiated a program in 2007 to collect lice from the homeless to test for b. quintana and to educate the homeless and their caregivers on prevention and control of louse-borne disease. during 2007-2008, 33.3% of bod ...200919523290
rapid and cost-effective identification of bartonella species using mass spectrometry.bacteria of the genus bartonella are emerging zoonotic bacteria recognized in a variety of human diseases. due to their poor chemical reactivity, these fastidious bacteria are poorly characterized using routine phenotypic laboratory tests. identification is usually achieved using molecular techniques that are time-consuming, expensive and technically demanding. recently, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) has emerged as a new technique for ...200919528172
the differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens.during evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. however, some alpha-proteobacteria are stealthy intracellular pathogens not readily detected by this system. brucella members follow this strategy and are highly virulent, but other brucellaceae like ochrobactrum are rhizosphere inhabitants and only opportunistic pathogens. to gain insight into the emergence of the stealthy strategy, we compared these two phylogenetically close but biologically ...200919529776
bartonella endocarditis: a pathology shared by animal reservoirsand patients.bartonellae were first recognized to cause endocarditis in humans in 1993 when cases caused by bartonella quintana, b. elizabethae, and b. henselae were reported. since the first isolation of bartonella vinsonii subspecies berkhoffii from a dog with endocarditis, this organism has emerged as an important pathogen in dogs and an emerging pathogen in people. subsequently, four types of b. vinsonii subsp. berkhoffii have been described, all of which have been associated with endocarditis in dogs. a ...200919538271
insights in bartonella host specificity.the genus bartonella comprises a unique group of emerging gram-negative, intracellular bacteria that can cause a long-lasting intraerythrocytic bacteremia in their reservoir hosts. in recent years, the widespread occurrence and diversity of these bacteria has been increasingly recognized. this has resulted in a dramatic expansion of the genus bartonella to 24 currently described species or subspecies, among which at least half have been associated with human disease. bartonella infections have b ...200919538272
seroprevalence of bartonella henselae in patients with uveitis and healthy individuals in tokyo.to compare the seroprevalence of bartonella henselae, a pathogen of cat scratch disease, in patients with uveitis and in healthy individuals.200919847604
prevalence and genetic heterogeneity of bartonella strains cultured from rodents from 17 provinces in thailand.to study the distribution and diversity of bartonella in rodents from thailand, 330 rodents belonging to 13 species were tested. the majority (80.6%) of rodents examined belonged to the genus rattus. bartonellae were cultured from 41.5% of the rodents with a wide range of prevalence by host species and regions. sequencing of glta revealed diverse bartonella strains. bartonellae from rattus spp. belonged to 23 variants and clustered with bartonella coopersplainensis, bartonella elizabethae, barto ...200919861616
[investigation of bartonella henselae seroprevalence and related risk factors in blood donors admitted to pamukkale university blood center].bartonella henselae is an emerging infectious agent that mainly causes cat scratch disease, basillary angiomatosis and peliosis hepatitis. although many basillary angiomatosis cases have been reported especially from the mediterranean region of turkey, adequate data about the seroprevalence of b. henselae in turkey does not exist. the aim of this study was to investigate the seroprevalence of b. henselae in volunteer blood donors and the related risk factors. in this study, sera samples were ran ...200919795614
a serologically proven case of cat-scratch disease presenting with neuroretinitis.cat-scratch disease is a clinical syndrome that usually presents as a self-limiting illness featuring regional lymphadenopathy, fever, and small skin lesions in association with a cat scratch or bite. it is caused by the gram-negative bacillus bartonella henselae, which commonly affects children and young adults. ocular bartonellosis is the most common atypical manifestation of cat-scratch disease. it can present with a wide spectrum of ocular diseases including neuroretinitis, parinaud's oculog ...200919801700
[cat-scratch disease with bone compromise: atypical manifestation].fever, headache, myalgias and lymphadenopathy are characteristic manifestations of cat-scratch disease but other less common findings are described in 2 to 10% of cases. we report two children that presented with hepatosplenic abscesses and bone involvement. one child, had multiple areas of increased uptake in the bone scintigram with a positive serology (igg > 1/256, igm slightly positive). the second child had destruction of the l2 vertebral body that compromised the channel and right foramen ...200919802407
blood transfusion as an alternative bartonellosis transmission in a pediatric liver transplant. 200919804481
[fever and abdominal pain in a 56-year-old woman]. 200919815317
receptor recognition of and immune intracellular pathways for veillonella parvula lipopolysaccharide.veillonella parvula is an anaerobic gram-negative coccus that is part of the normal flora of the animal and human mouth and gastrointestinal and genitourinary tracts. oral v. parvula is involved in the development of early periodontal disease as well as different types of serious infections. present data on molecular mechanisms responsible for innate immune response against veillonella are very scanty. the aim of this study was to investigate the toll-like receptor (tlr) pathways responsible for ...200919828771
fatal myocarditis-associated bartonella quintana endocarditis: a case report.bartonella spp. infection is not rare and must be considered with great care in patients with suspected infective endocarditis, particularly if regular blood cultures remain sterile. management of these infections requires knowledge of the identification and treatment of these bacteria.200919830188
babesia canis and other tick-borne infections in dogs in central poland.vector-borne infections constitute increasing health problem in dogs worldwide, including sled dogs, dramatically decreasing the fitness of working dogs and even leading to death. in the period 2006-2008 eighty-two blood samples were collected from eight sled dog kennels in central poland. the prevalence of four vector-borne infections (babesia canis, bartonella sp., anaplasma/ehrlichia and borrelia burgdorferi) was estimated in 82 sled dogs using pcr and nested pcr for diagnosis and the same me ...200919837515
detection of babesia canis subspecies and other arthropod-borne diseases in dogs from tirana, albania.summary. the importance of arthropod-borne diseases increased in the recent past in particular due to frequent travel with dogs in or by importing of dogs from regions with endemic occurrence of these diseases. while the epidemiological situation is well known for the western parts of the mediterranean, only limited data is available for eastern europe and the balkans. thirty clinically healthy dogs from suburban areas of tirana, albania, were tested for babesia canis, hepatozoon spp., leishmani ...200919915816
bartonella species detected in rodents and hedgehogs from algeria. 200919929978
molecular characterisation of resistance to rifampin in bartonella quintana. 200919929979
no etiological role for bartonella henselae infection in henoch schönlein purpura. 200919935277
detection and identification of bartonella sp. in fleas from carnivorous mammals in andalusia, spain.a total of 559 fleas representing four species (pulex irritans, ctenocephalides felis, ctenocephalides canis and spilopsyllus cuniculi) collected on carnivores (five iberian lynx lynx pardinus, six european wildcat felis silvestris, 10 common genet genetta genetta, three eurasian badger meles meles, 22 red fox vulpes vulpes, 87 dogs and 23 cats) in andalusia, southern spain, were distributed in 156 pools of monospecific flea from each carnivore, and tested for bartonella infection in an assay ba ...200919941605
[genetic diversity of ixodid tick-borne pathogens in tomsk city and suburbs].we studied two urban and two suburban biotypes of tomsk city for tick-transmitted diseases prevalence in naturally collected ticks. tick-borne encephalitis virus (tbev) was found in 6.5% of tick samples, west nile virus (wnv) in 2.2%, borrelia spp. in 8%, rickettsia spp. in 2.5%, and ehrlichia spp. in 1.7% of samples. genetic markers of powassan virus, bartonella spp., and balbesia spp. were not found. analysis of the genetic diversity of revealed pathogens resulted in the following conclusions: ...200919957906
[cat scratch disease--an underestimated diagnosis].cat scratch disease is a rare and frequently underestimated cause of lymphadenopathy, which may occur also in the head and neck. the infection is most commonly caused by intracellular bacilli bartonella, transmitted by domestic animals.200919886535
bartonella rochalimae in raccoons, coyotes, and red foxes.to determine additional reservoirs for bartonella rochalimae, we examined samples from several wildlife species. we isolated b. rochalimae from 1 red fox near paris, france, and from 11 raccoons and 2 coyotes from california, usa. co-infection with b. vinsonii subsp. berkhoffii was documented in 1 of the coyotes.200919961681
cat scratch disease presenting with a retroperitoneal abscess in a patient without animal contacts.cat scratch disease (csd) is usually diagnosed in patients presenting with regional lymphadenopathy and pyrexia that follow contacts with animals. we describe here a young adult male patient who presented with marked pyrexia and a retroperitoneal abscess without relevant medical histories, illustrating that csd can be a diagnostic challenge on selected occasions.200920012734
[pandora's box: pathogens in ixodes ricinus ticks in central europe].among the various species of hard ticks, ixodes ricinus is the most frequently found tick throughout europe. as with other ixodid ticks, the developmental cycle runs through three stages. in each stage a blood meal is required in order to develop to the next stage. ixodes ricinus has been found to feed on more than 300 different vertebrate species. usually, larval ticks feed on small mammals such as mice and become infected with various microorganisms and viruses, of which some are substantial p ...200919998007
a groundhog, a novel bartonella sequence, and my father's death. 200919998749
bartonella henselae neuroretinitis in a 15-year-old girl with chronic myelogenous leukemia.a 15-year-old girl being treated with imatinib for chronic myelogenous leukemia (cml) presented with acute vision loss in her right eye accompanied by swelling of the right side of her neck. on examination, she was found to have disk and macular edema of the right eye. fine-needle aspiration and excisional biopsies of an enlarged submandibular lymph node were negative for malignancy. although initial serologies were equivocal for bartonella henselae, repeat serologies performed 1 week later upon ...200920006827
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