Publications

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fluorosis, osteopetrosis, and ectopic calcification. 20072223455
the antiphospholipid antibody dilemma. 20072168305
quantitation of hormone replacement induced withdrawal bleeds. 20071847822
response by dr. alden n. haffner upon receipt of the koch memorial medal 1990. 20071852404
personal power: your key to success. 20072216083
mammography quality assurance. 20071950889
[bone marrow necrosis. apropos of 2 cases]. 20072933830
pet in generalized anxiety disorder.positron emission tomography (pet) measurements of cerebral glucose use were made in 18 patients with generalized anxiety disorder (gad) during a passive viewing task off medication, and an active vigilance viewing task before and after medication or placebo treatment. in the passive viewing task, patients with gad were compared with 15 normal controls. a significant difference in pattern of absolute brain metabolism was found. patients showed lower absolute metabolic rates in basal ganglia and ...20071888800
[amalgam discussion. question of amalgam toxicity and allergy]. 20072171028
lightness, embeddedness, and contrast. 20075054071
scalp cooling by cold air for the prevention of chemotherapy-induced alopecia.a new system is described for cooling the scalp with cold air in order to prevent chemotherapy-induced alopecia. compressed air was cooled by means of a vortex tube built into a hair-drier cap. this system reduced the blood flow in the scalp to 35%, the surface temperature to 14.2 degrees c and the intradermal temperature at hair follicle level to 29.2 degrees c. the low temperature could be kept constant for at least one hour of cooling. by means of comparison, with cryogel packs the lowest epi ...20072074916
glucagon and clonidine testing in the diagnosis of pheochromocytoma.we assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor. in the glucagon stimulation test, blood was sampled 2 minutes after intravenous injection of 0.28 mumol (1 mg) glucagon, and in the clonidine suppression test, blood was sampled 3 hours after administration of oral clonidine, 1.30 mumol (0.3 mg)/70 kg body wt. baseline levels of catechols in antecu ...20072045133
acute intoxication as a cause of wild bird mortality in the netherlands from 1975-1989. 20071805755
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
somatostatin receptor incidence and distribution in breast cancer using receptor autoradiography: relationship to egf receptors.somatostatin receptors (ss-r) were measured with in vitro receptor autoradiography using the ss analog 125i-[tyr3]-sms 201-995 as radioligand in 342 breast-tumor samples. in a group of 158 "small" tumor samples (mean section surface: 14 mm2 +/- 0.4; mean +/- sem), 34 tumors (21%) were ss-r positive. in a group of 72 "large" tumor samples (mean size: 180 mm2 +/- 8; mean +/- sem), 33 tumors (46%) were ss-r positive. in this second group, more than half of the tumors had a non-homogeneous distribut ...20072168344
alcohol as a key area. 20071932941
[initial attitudes to orthodontic treatment--the results of a practical and clinical questionnaire study (i)].312 patients from one clinic and nine offices, between eight and 15 years of age treated with bionators, their parents and a control group were questioned on various aspects of their treatment. findings regarding opinions about dentofacial appearance, initial motives and expectations are presented. aesthetic motives proved preponderant by seeking treatment though the children's ability to verbally differentiate aesthetic concepts was poor. above all, they expected visible treatment progress, abs ...20072227739
[initial attitudes to orthodontic treatment--the results of a practical and clinical questionnaire study (i)].312 patients from one clinic and nine offices, between eight and 15 years of age treated with bionators, their parents and a control group were questioned on various aspects of their treatment. findings regarding opinions about dentofacial appearance, initial motives and expectations are presented. aesthetic motives proved preponderant by seeking treatment though the children's ability to verbally differentiate aesthetic concepts was poor. above all, they expected visible treatment progress, abs ...20072227739
[diagnosis and surgical treatment of traumatic damage to the sinus of valsalva following penetrating wounds of the heart].the authors had three patients with traumatic damage of the sinus of valsalva, caused by penetrating injury of the thorax inflicted with a knife. the patients were brought to the clinic in a grave condition with decompensation of systemic and pulmonary circulation. the anomaly called for emergency surgical correction under conditions of extracorporeal circulation. the diagnosis was based on the complaints, medical history, clinical picture, the results of functional methods of examination includ ...20072223226
[diagnosis and surgical treatment of traumatic damage to the sinus of valsalva following penetrating wounds of the heart].the authors had three patients with traumatic damage of the sinus of valsalva, caused by penetrating injury of the thorax inflicted with a knife. the patients were brought to the clinic in a grave condition with decompensation of systemic and pulmonary circulation. the anomaly called for emergency surgical correction under conditions of extracorporeal circulation. the diagnosis was based on the complaints, medical history, clinical picture, the results of functional methods of examination includ ...20072223226
[a congenital esophagotracheal fistula in an adult]. 20072223222
[a congenital esophagotracheal fistula in an adult]. 20072223222
[the diagnostic value of mr tomography following gadolinium-dtpa compared to computed tomography in bladder tumors].in a prospective study, 58 patients with carcinomas of the bladder were examined by ct and mri; in 48, gadolinium-dtpa was administered intravenously. mri provided exact staging in 89%, compared with 80% with ct. there was 13% over-staging with ct and 11% with mri. mri, unlike ct did not result in any under-staging. in 36 patients a quotient could be calculated from the signal intensity of the tumour and surrounding soft tissues both before and after the intravenous contrast medium and the incre ...20072168077
local control of operable breast cancer after radiotherapy alone.221 patients with operable breast carcinoma stage tis, t1, t2, t3, n0n1 were treated with radiotherapy alone without tumorectomy. the mean follow-up time was 15.5 years (range 5-22). the annual risk for local recurrence was 3% during the first 5 years and 1% during the following 10 years, resulting in an actuarial local control rate of 75.4% after 15 years. the risk for local recurrence was assessed in multivariate analysis and was significantly related to the size of the tumour measured on mamm ...20072168190
[a juvenile form of osteochondrosis]. 20072074966
dietary habits, sexual maturation, and plasma hormones in pubertal girls: a longitudinal study.the relationships between dietary components and physical or hormonal sexual maturation in 63 pubertal girls were examined. the effects of vegetable protein and dietary fiber on breast development (b = -2.0, p less than 0.05; b = -2.6, p less than 0.05, respectively) became more pronounced in a multivariate analysis, after elimination of the linear effects of body height and energy intake. from the multivariate analysis with combinations of vegetable protein, polysaccharides, and fiber in the eq ...20071951150
radiographic examination of the lumbar spine in a community hospital: an audit of current practice.to assess general practitioners' decisions to request lumbar spine radiographs according to the guidelines of the royal college of radiologists.20071932970
occult rupture of spleen. 20071800517
another look at viq-piq scores and unilateral brain damage.the relationship of wais, viq, piq and aphasia screening scores to unilateral brain damage was investigated using 18 subjects with left hemisphere damage (lhd) and 19 subjects with right hemisphere damage (rhd). expected viq-piq difference scores were demonstrated only for the rhd subjects. aphasia was significantly associated with piq in the lhd group. ancovar using aphasia screening as a covariate produced significant lhd versus rhd differences on piq. these data question the utility of viq-pi ...20083699998
rolipram in major depressive disorder: results of a double-blind comparative study with imipramine.rolipram improves signal transmission in central noradrenergic neurones at a pre- and postsynaptic level, and is thus a novel approach in antidepressant therapy. in order to prove efficacy, tolerance, and safety, several controlled studies are underway. results of a randomized double-blind comparative trial versus imipramine involving 64 in-patients with major depressive disorder (dsm iii) in six independent centers will be presented and discussed. the chosen biometric model provided evidence th ...20082668980
solving problems: down the yellow brick road. 20082600651
percutaneous fine needle aspiration biopsy using a modified coaxial technique.a modified coaxial technique for the biopsy of small or deeply situated lesions using computed tomographic (ct) guidance is described. a 22-gauge needle was passed coaxially through an outer 18-gauge introducing needle and aspiration biopsy was performed. this modified coaxial technique allows for multiple biopsies to be obtained safely, expeditiously, and repeatedly.20082496928
[ocular herpes zoster with contralateral hemiplegia].a total of 375 patients with neurologic syndromes of herpes zoster were studied. ten of them presented, along with the involvement of the first branch of the trigeminal nerve and other cranial nerves, contralateral pyramidal symptomatology. apart from the typical syndrome of herpes zoster ophthalmicus with contralateral hemiplegia the authors distinguished clinical variants in which contralateral pyramidal symptomatology was associated with acute meningoencephalitis.20083259770
effect of psoralens and ultraviolet radiation on murine dendritic epidermal cells.monofunctional psoralens produce less phototoxicity than bifunctional psoralens after ultraviolet a (uva) irradiation. we investigated the effect of repetitive treatments with angelicin (isopsoralen), a monofunctional psoralen, plus uva radiation (ipuva) on the number and morphology of dendritic epidermal cells (dec). this effect was compared with that of 8-methoxypsoralen plus uva radiation (puva), uva alone, and uvb radiation. c3h/hen mice were treated topically with the drugs three times/wk f ...20082565931
ovarian suppression induced with buserelin or danazol in the management of endometriosis: a randomized, comparative study.the effectiveness of buserelin (hoechst-roussel pharmaceuticals, inc., somerville, nj) (0.2 mg subcutaneously [sc] or 1.2 mg intranasally [in] per day) and danazol (800 mg per day) in inducing ovarian suppression for the management of endometriosis was compared in a prospective randomized study. during 6 months of treatment, peripheral follicle-stimulating hormone (fsh), luteinizing hormone (lh), and estradiol concentrations were suppressed to a similar degree in both groups. symptomatic improve ...20082493400
use of indium-111 as a red cell label.to select the most promising 111in chelate for use as a second red cell (rbc) label for comparison of the survival of autologous and allogeneic cells, 49 normal rbc samples were studied in vitro after being labeled with 111in-8-hydroxyquinolinol (111in-oxine) prepared by three different methods, 111in-tropolone, and 111in-acetylacetone. labeling efficiencies reached 99 percent and did not decline when the amount of 111in used was increased from 1.75 to 50 muci per ml of rbcs. storage of labeled ...20082493173
aging and compartmentalization of the mucosal immune system. 20082447761
protocol for rapid chemical rna sequencing. 20082443900
fractionated ifosfamide therapy produces a time-dependent increase in ifosfamide metabolism.1. fifteen patients received 1.5 g m-2 of ifosfamide intravenously over 0.5 h every day for 5 days. twenty-one courses of treatment were studied. plasma was assayed for ifosfamide by gas liquid chromatography and plasma alkylating activity was measured using the nitrobenzylpyridine (nbp) reaction. 2. a pharmacokinetic analysis revealed a significant decrease in the median (range) elimination half-life of ifosfamide from 7.2 (2.8-14.2) h on day 1 to 4.6 (2.3-7.7) h on day 5 (p less than 0.001, wi ...20082271371
[alpha-amylase polymorphism. 1. a comparative study of alpha-amylase hp and gm].individual phenotypes, phenotypical and genetic frequencies of the alpha-amylase enzyme have been established by means of populational genetic researches. the most common phenotype is amyla amyl2a (85.15%) followed by amyla amyl2a 2b (6.27%), amylaib amyl2a (5.37%), amyl ia amyl2a 2b (2.15%), amyla amyl2b (0.53%), amylc amyl2b (0.35%), amylc amyl2a 2b (0.18%). the difference between the observed and theoretically expected phenotypes of amy, hp and m gm(1) is insignificant. the examined contingen ...20082627896
use of endoscopic laser in gastroenterology.in this presentation we report the current use of endoscopic laser in gastroenterology in japan with the results of a nation-wide survey and our own experience with more than 100 cases. nd:yag laser (photocoagulative therapy) and argon dye laser with hematoporphyrin derivative (photodynamic therapy) were most commonly used in digestive endoscopy, and were investigated as new modalities of cancer therapy and detection. by november 1985, 1588 of gastrointestinal (gi) cancers had been treated in ja ...20082446562
colony-stimulating factor and drug-induced agranulocytosis. 20082655524
colony-stimulating factor and drug-induced agranulocytosis. 20082655524
tcnu in adenocarcinoma of the lung: a phase ii study with divided doses.tcnu, a new water soluble nitrosourea, has in preclinical studies shown higher activity when given as divided doses compared with one day single treatment. accordingly, 38 consecutive patients with non-resectable adenocarcinoma of the lung received tcnu 40 mg/m2 p.o. daily for three days every 4 weeks. the response rate among 37 evaluable patients was 14%, median response duration was 17 weeks (range 5-57+ weeks) and median survival 22 weeks (range 3-96+ weeks). hematologic toxicity was pronounc ...20082265139
design, methods, and rationale in the hypertension prevention trial. hypertension prevention trial research group.the hypertension prevention trial (hpt) was a randomized, controlled, multicenter (four clinics, four resource centers) trial designed to test the feasibility of achieving and sustaining dietary changes in the intake of calories, sodium, and potassium and to assess the effect of those changes on blood pressure in a normotensive population. the trial involved 841 men and women (plus a test cohort of 78) who, at the first baseline (bl) examination, were in the age range of 25-49 years and had dias ...20082680271
binding modes of mammalian hepatic gal/galnac receptors.mammalian gal/galnac receptors show dramatic preference for three-branched oligosaccharide structures over two- or one-branched counterparts. the spatial arrangement of the gal residues is extremely important for optimal binding. the three terminal gal residues in the best triantennary ligand are about 15-30 a apart, and therefore the sugar-combining sites on the receptor may also have the same geometry. the results obtained with synthetic ligands containing gal or galnac are in agreement with t ...20082551610
non-germ cell testicular tumours in nigerians.non-germ cell testicular tumours are reported to be more common in peoples of negroid and asian descent than in caucasians. this group of tumours comprised seven of sixteen testicular tumours seen in a ten-year period at the university of benin teaching hospital, benin city, nigeria. however, unlike experiences elsewhere in africa and the west indies where paratesticular tumours accounted for a majority of these tumours, malignant lymphomas constituted over 70% of non-germinal testicular tumours ...20082635452
non-germ cell testicular tumours in nigerians.non-germ cell testicular tumours are reported to be more common in peoples of negroid and asian descent than in caucasians. this group of tumours comprised seven of sixteen testicular tumours seen in a ten-year period at the university of benin teaching hospital, benin city, nigeria. however, unlike experiences elsewhere in africa and the west indies where paratesticular tumours accounted for a majority of these tumours, malignant lymphomas constituted over 70% of non-germinal testicular tumours ...20082635452
[the gynecology clinic in the era of electronic data processing]. 20082583592
[neoplasms of the meckel diverticulum. apropos of 2 new cases].we present two new cases of cancer in a meckel's diverticulum, representing 3.3% of the complicated meckel's diverticula encountered in our department. the first case was a carcinoid tumor encountered in a pathology study of an inflamed meckel's diverticulum, and the second case was a leiomyosarcoma on a meckel's diverticulum that presented as diverticular perforation. we emphasize the advanced age of the two patients and review the cases reported in spain and in the western literature.20082346684
panic attacks, buspirone, and serotonin function. 20082570299
[therapy monitoring of regional chemotherapy by magnetic resonance spectroscopy]. 20082474953
diversity of glucose entry routes in the enterobacteriaceae. 20082561261
evaluating the optometric literature: the educated clinician.the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature.20082703662
evaluating the optometric literature: the educated clinician.the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature.20082703662
american academy of pediatrics: prep statement. 20082587145
[a case of posttraumatic cerebral air embolism].we report a case of cerebral air embolism that occurred after chest trauma. the diagnosis was confirmed by ct and skull roentgenogram which demonstrated air bubbles in intracranial arteries. it is well recognized that cerebral air embolism is caused by various diagnostic and therapeutic procedures, and trauma. but it may often be overlooked because it is diagnosed clinically and there are no characteristic symptoms nor signs. although various ways of treatment have been reported, prevention and ...20082586716
[prostheses on osteointegrated implants: restoration of a missing tooth (4)].this article is the last of a series of four. this article describes in detail the fabrication of a crown connected to a brånemark implant.20082394869
[regional blood lactate level in arterial occlusive diseases].fifty-seven patients with obliterating diseases of the lower limb arteries were examined. the concentration of lactate in the venous blood and the venous-arterial difference in the blood lactate level in the affected limb were found to be increased. a relationship between the marked character of these shifts and the severity of the ischemic syndrome was noted. the authors discuss the possibility of using the values of the lactate content in the regional blood as criteria for evaluating the effic ...20082292851
pathogenesis of minimal change nephropathy. 20082362129
suppression. 20082533505
nasal mucosal temperature and the effect of acute infective rhinitis.nasal mucosal temperature was measured in 71 healthy subjects with an electronic thermometer. no correlation was found between the nasal mucosal temperature and age or sex. an increased mucosal temperature was found in patients with acute rhinitis, an effect which is supposed to assist in the defence system against microorganisms. when measuring nasal mucosal temperature over a 7-h period at the same time as nasal airway resistance, there was no correlation between these factors, indicating that ...20082612033
application of automated on-line microbore high-performance liquid chromatography/capillary gas chromatography to diesel exhaust particulates. 20082446529
efficacy of neuromuscular stimulation of the quadriceps femoris during continuous passive motion following total knee arthroplasty.the effect of neuromuscular stimulation of the quadriceps femoris combined with continuous passive motion (cpm) on the active extension range of motion and force of patients with total knee arthroplasty was investigated. the experimental group received three one-hour periods of electric stimulation per day in the extension cycle of the continuous passive motion. the control group received continuous passive motion without quadriceps electric stimulation. both groups engaged in physical therapy c ...20083259866
[macular disorders and carotid digital angiography]. 20082590966
assessment of clinical application of test-dose concept for theophylline in patients with respiratory failure.the possibility of clinical application of test-dose concept for theophylline was assessed in 11 patients with serious underlying disease who required theophylline. based on the pharmacokinetic parameters calculated from the single intravenous aminophylline administration, they received a continuous infusion of aminophylline in order to maintain about 10 micrograms/ml plasma which is considered to be the lowest therapeutic level. plasma levels during a constant rate infusion were assayed at 6:00 ...20082630628
assessment of clinical application of test-dose concept for theophylline in patients with respiratory failure.the possibility of clinical application of test-dose concept for theophylline was assessed in 11 patients with serious underlying disease who required theophylline. based on the pharmacokinetic parameters calculated from the single intravenous aminophylline administration, they received a continuous infusion of aminophylline in order to maintain about 10 micrograms/ml plasma which is considered to be the lowest therapeutic level. plasma levels during a constant rate infusion were assayed at 6:00 ...20082630628
[experience with dilatation of tight esophageal stenoses using a balloon catheter].the dilatation of oesophageal stenoses with balloon catheters was made in 38 patients with 44 stenoses of different origin. the most frequent stenosis was localized in oesophagogastric or oesophagocolic anastomosis after oesophagectomy, postcorrosive stenoses an those after reflux oesophagitis. the stenoses were mostly of filiform type, the diameter being 1-3 mm (79%) less frequently 4-7 mm (21%). it became possible to dilate 37 stenoses up to 10 to 20 mm, four stenoses to 22 mm. in only three c ...20082632022
[experience with dilatation of tight esophageal stenoses using a balloon catheter].the dilatation of oesophageal stenoses with balloon catheters was made in 38 patients with 44 stenoses of different origin. the most frequent stenosis was localized in oesophagogastric or oesophagocolic anastomosis after oesophagectomy, postcorrosive stenoses an those after reflux oesophagitis. the stenoses were mostly of filiform type, the diameter being 1-3 mm (79%) less frequently 4-7 mm (21%). it became possible to dilate 37 stenoses up to 10 to 20 mm, four stenoses to 22 mm. in only three c ...20082632022
[the experience of severe complication in the surgical treatment of chronic subdural hematoma: the usefulness of the burr hole and continuous closed system drainage].seventy-four cases of chronic subdural hematoma were treated by burr hole with irrigation (31 cases), and burr hole and closed system drainage with slow decompression (43 cases). the postoperative changes of the clinical symptoms and ct findings in both groups were compared. markwalder's clinical grading was used for evaluating the clinical symptoms. preoperative grade distribution was as follows, 16 cases in grade 1, 12 cases in grade 2, 3 cases in grade 3 and no case in grade 4 in the irrigati ...20082586712
phrenic involvement in charcot-marie-tooth disease. a pathologic documentation.a 69-year-old woman diagnosed as having charcot-marie-tooth disease (cmt) for 30 years' duration died of respiratory failure secondary to diaphragmatic weakness. at autopsy, identical neuropathic changes were found in phrenic and other affected somatic peripheral nerves. we conclude that the phrenic nerve may be involved by the neuropathy of at least some forms of cmt.20082553346
[results of synovectomy of the elbow joint in chronic polyarthritis]. 20082576709
[short- and medium-term treatment of ventricular hyperkinetic arrhythmia with flecainide].our study group included 12 patients (4 males, 8 females), mean age 60 yr, with symptomatic or threatening tachyarrhythmias (lown classes iv a, b, v); 2 patients were suffering from mitral valve prolapse syndrome, 2 from ischemic heart disease; 4 from cardiac insufficiency caused by hypertensive or ischemic heart disease; 4 had no evident clinical signs of cardiopathy. patients suffering from: cardiac insufficiency (f.c. iii e iv nyha); ii and iii degree bav; atrial flutter and fibrillation; lon ...20082527112
the biology of the scid mutation. 20082519515
endodermal sinus tumor and embryonal carcinoma of the ovary in children.the clinicopathological features of 26 pure endodermal sinus tumors (est) and for embryonal carcinomas of the ovary occurring in children under age 15 years in britain over the period 1962-1978 are described. endodermal sinus tumor has shown a significant increase (p less than 0.001) over the 17-year period considered. compared to controls, est and embryonal carcinoma have not shown an association with the use of hormones or tranquilizers during pregnancy, with radiological investigations, or wi ...20082580758
improved synthesis and iodination of a cleavable photoactivated probe.j. b. denny and g. blobel (1984, proc, natl. acad. sci. usa 81, 5286-5290) have described the synthesis of a water-soluble novel heterobifunctional 125i-labeled photocrosslinking reagent, n-[4-(p-azido-m-[125i]iodophenylazo)benzoyl]-3-aminopropionyl-n'- oxysulfosuccinimide, which contains a cleavable internal azo bond. we report several modifications of their synthesis which greatly increase the yield of a synthetic intermediate, n-[4-(p-aminophenylazo)benzoyl]-3-aminopropionic acid (compound vi ...20082446528
age distribution of erythrocyte population in late pregnancy.the age population distribution of erythrocytes in late pregnancy was evaluated by the volume and density distribution of cells. this approach enables an evaluation of the life span of erythrocytes in the circulation without using radioactive elements. a younger cell population was found in the circulation of women in late pregnancy as compared to nonpregnant women of similar ages, which might be indicative of shortened life span of erythrocytes. this shortened life span might be explained by th ...20082265799
[a training program after coronary surgery improves blood lipid profile]. 20082263103
[focal liver lesions as incidental findings. 2: diagnostic procedures in sonographically homogeneous echo-rich, echo-poor or inhomogeneous lesions].hemangioma is one of the most common incidental findings in the ultrasonographic image. in 80% to 90% of the cases, the hemangioma presents as a homogeneous lesion in the us image. in asymptomatic patients and a lesion diameter of less than 2 cm, further clarification additional to ultrasonography is not necessary. major differential diagnoses are focal nodular hyperplasia, metastasis, hepatocellular carcinoma and liver cell adenoma. with exceptions, the biological significance of echo-poor or i ...20082242838
[technical problems of various sanitary-hygienic aspects of a medical unit on space aircraft]. 20082292877
use of high-pass filtering to detect late potentials in the signal-averaged ecg.the authors investigate the use of digital filters for analysis of the signal-averaged ecg. they consider the basic types of digital filters and examine respective advantages and disadvantages for ecg analysis. an approach to analyzing the signal-averaged ecg using separate filters for measuring qrs offset and amplitudes is proposed. a study of 19 subjects explores the use of filters to detect low-level activity anywhere in the qrs complex.20082614317
criteria that discriminate between native proteins and incorrectly folded models.various theoretical concepts, such as free energy potentials, electrostatic interaction potentials, atomic packing, solvent-exposed surface, and surface charge distribution, were tested for their ability to discriminate between native proteins and misfolded protein models. misfolded models were constructed by introducing incorrect side chains onto polypeptide backbones: side chains of the alpha-helical hemerythrin were modeled on the beta-sheeted backbone of immunoglobulin vl domain, whereas tho ...20083186690
[nuclear magnetic resonance in the diagnosis of multiple sclerosis. a critical review of the literature].nuclear magnetic resonance (nmr) has been proposed to be the best diagnostic test for multiple sclerosis (ms). we performed a critical analysis of 13 papers evaluating the use of nmr in ms. out of an ideal 17 criteria for validation and reproducibility, a top of 11 (65%) was the maximum found. foremost deficiencies were a lack of blind analysis and inadequate patient samples. thus the claim that nmr is the diagnostic tool of choice in ms remains to be proven.20082519356
[a case of asymptomatic course of kidney tumor]. 20082292876
[nosocomial infection at a regional hospital]. 20082490734
reflex sympathetic imbalance. response to epidural blockade.eleven patients (two male, nine female) were treated with epidural sympathetic blockade for reflex sympathetic imbalance, an incomplete manifestation of reflex sympathetic dystrophy. each had developed severe pain, sensitivity, and disability disproportionate to associated trauma. one patient injured an ankle, and the remaining 10 patients one or both knees (12 knees). seven patients had undergone previous surgery. all but one had a favorable response to initial blockade. this individual eventua ...20082610282
phytochrome from the green alga mesotaenium caldariorum. purification and preliminary characterization.a method to purify the phytochrome photoreceptor from the unicellular green alga mesotaenium caldariorum is presented. preparative scale formation of algal protoplasts and controlled osmotic cell lysis have permitted separation of intact organelles from the phytochrome-enriched soluble protein fraction. we have utilized the observation that red light-absorbing (pr) and far-red light-absorbing (pfr) forms of phytochrome are differentially retained on an anion exchange matrix to purify m. caldario ...20082324111
cystic neoplasms of the pancreas.eight patients with cystic neoplasms of the pancreas were seen at four northern california hospitals between the years 1978 and 1986. three of the tumors were benign and five were malignant. three females, whose average age was 61 years, had cystadenomas. three females and two males, whose average age was 48 years, had mucinous cystadenocarcinomas. clinical presentations were similar among all patients. abdominal pain was a prominent feature. anorexia, weight loss, nausea and vomiting with a pal ...20082446398
[diet in the prevention of coronary disease]. 20083815423
[diet in the prevention of coronary disease]. 20083815423
[reiter's syndrome or lyme disease?]. 20082632003
[reiter's syndrome or lyme disease?]. 20082632003
improvement in airway responsiveness and asthma severity during pregnancy. a prospective study.in the myometrium and gut, smooth muscle becomes less contractile during pregnancy, probably because of the effect of progesterone and estrogen. it is not known whether these hormones cause similar changes in airway smooth muscle, and therefore, this study examined airway responsiveness during the large hormonal changes of pregnancy and evaluated whether changes in responsiveness are associated with changes in (1) progesterone and estrogen and (2) the clinical severity of asthma. twenty nonpregn ...20082679270
autocrine regulation of 1,25-dihydroxycholecalciferol metabolism in myelomonocytic cells.in this study the effects of vitamin d metabolites on the myelomonocytic precursor cell line u937 have been compared with those of phorbol myristate acetate (pma). pma was used as a cell modulating agent in order to avoid effects of binding of the exogenous vitamin d metabolites receptors within the cell, which would interfere with subsequent measurement of these receptors in studies of the vitamin d3 metabolic pathway. both the active 1,25 dhcc form of vitamin d3 and the inactive 24,25 dhcc met ...20082553587
maize phosphoenolpyruvate carboxylase involved in c4 photosynthesis: nucleotide sequence analysis of the 5' flanking region of the gene.to clone the genomic dna fragment containing the putative promoter region of the gene for phosphoenolpyruvate carboxylase [ec 4.1.1.31] involved in c4 photosynthesis (c4-type pepc), maize genomic libraries were screened. on probing with a 384-bp fragment from the n-terminal coding region of the maize cdna for c4-type pepc, four ecori-fragments differing in the restriction map were cloned, reflecting the presence of a small gene family. southern blot analyses were carried out on the genomic dna a ...20082628434
a simple and inexpensive method for preparing erythrocyte membranes by filtration through a hollow-fiber system.an efficient, simple method for preparing biologically active erythrocyte membranes is described. the semi-automated procedure involves circulating hemolysate mixture through a hollow-fiber system, thereby filtering off intracellular components leaving a high yield of washed ghosts. the prepared ghosts exhibit cation-stimulated atpase activities comparable to those of ghosts prepared by traditional methods. electron micrographs revealed that the filtration isolation caused less shearing of the m ...20082527009
comparative study of the circadian rhythmicity in the urinary concentration of glycosaminoglycans in patients of calcium oxalate nephrolithiasis and in healthy adults.glycosaminoglycans (gags) are potent inhibitors of calcium oxalate crystallisation and/or crystal aggregation. urinary concentration of gags has been shown to vary during 24 h; therefore, circadian rhythmicity in urinary concentration of gags was investigated in 33 healthy male adults in the age group of 20-40 years and in 27 male patients of a similar age group with calcium nephrolithiasis. three-hourly urine samples were collected for 24 h beginning from 00.00 h for estimation of urinary conce ...20082800054
[cardiac tamponade as the first manifestation of cancer].we report 3 patients having cardiac tamponade as the initial presentation of cancer. at the onset of symptoms all three patients were incorrectly diagnosed. pulsus paradoxus and cardiomegaly on the chest x-ray were the main clinical features. two dimensional echocardiography was vital revealing massive pericardial effusion with diastolic right atrial and ventricular collapse. all patients had bloody pericardial fluid removed and the histopathology of the metastatic pericardial tissue showed lung ...20082519419
[intermittent intra-arterial infusion chemotherapy of intrapelvic malignancy]. 20082443898
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