Publications

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resistance to lyophilization of salmonella typhi, escherichia coli and shigella flexneri strains. 1979400513
shigellae and reiter's syndrome. 1979400766
phenylalanyl-trna synthetase induced conformational change of escherichia coli trna phe. 1979383142
salmonella phage glycanases: substrate specificity of the phage p22 endo-rhamnosidase.interaction between phage p22 and phenol-water extracted lipopolysaccharides from sensitive salmonella bacteria belonging to serogroups a, b and di results in hydrolysis of the alpha-l-rhamnosyl linkages within the tetrasaccharide repeating unit of the o-antigenic polysaccharide chain. these o-antigens have identical structures except for the nature of the 3,6-dideoxy-hexosyl group linked to o-3 of the d-mannosyl residue. removal of the dideoxysugar, or periodate oxidation followed by borohydrid ...1979383902
[humoral factor study of natural immunity in sonne and flexner dysenteries]. 1979386651
[seasonal problems of bacterial dysentery in the dagestan assr].during the period of 1959-1973 bacterial dysentery showed high morbidity rate in daghestan in all seasons, this tendency existing both in urban and rural areas. the peculiarity of the monthly distribution of dysentery cases, observed all over the repulic, was the shift of the morbidity peak from august to september-october, and in some years even to november; this could be clearly observed from the analysis of the material as a whole and from the analysis of dysentery morbidity rates in rural an ...1979386661
[transduction analysis of the genetic control of synthesis of the r-nucleus of the lipopolysaccharide of o-antigen]. 1979386667
[role of histamine in the development of inflammation of the large intestine mucosa in acute dysentery]. 1979370753
the enzymes of the galactose cluster in saccharomyces cerevisiae. purification and characterization of galactose-1-phosphate uridylyltransferase. 1979387754
synthesis and properties of fluorescent nucleotide substrates for dna-dependent rna polymerases.a new class of fluorescent nucleotide analogs which contain the fluorophore 1-aminonaphthalene-5-sulfonate attached via a gamma-phosphoamidate bond has been synthesized. both the purine and pyrimidine analogs have fluorescence emission maxima at 460 nm. cleavage of the alpha-beta-phosphoryl bond produces change in both the absorption and fluorescence emission spectra. the fluorescence of the pyrimidine analogs is quenched; cleavage of the alpha-beta-phosphoryl bond of the utp analog produces abo ...1979387781
api and minitek systems in identification of clinical isolates of anaerobic gram-negative bacilli and clostridium species.a comparison of the api and minitek methods of biochemical testing was made on a variety of anaerobic bacteria. although api and minitek results were not compared to more standardized or conventional procedures of identification, multiple repeat testing of the two systems was done on routine clinical isolates and known organisms to determine (i) whether the reactions were reliably consistent, (ii) the ease of reading the two systems with respect to the frequency of questionable results, and (iii ...1979387809
characterization of plasmids from antibiotic-resistant shigella isolates by agarose gell electrophoresis.gel electrophoresis of dna from 95 clinical isolates of shigella sonnei and shigella flexneri resistant to antibiotics revealed a heterogeneous plasmid population. most of the plasmids were smaller than 6 megadaltons (mdal). six s. sonnei isolates with the most common antibiotic resistance pattern were characterized. they had two plasmids in common: one was a self-transmissible fi+ plasmid of 46 mdal encoding resistance to streptomycin and sulphafurazole. in addition, several cryptic plasmids ra ...1979387914
[clinical and pathogenetic comparisons with allergization in flexner and sonne dysentery]. 1979388063
[comparative characteristics of the clinical course of flexner and sonne dysenteries during the warm and cold periods of the year]. 1979388064
[comparative effectiveness of the treatment of acute dysentery]. 1979388065
shigella dysenteriae, sh flexneri, and sh boydii infections in england and wales: the importance of foreign travel. 1979389342
macrophage functions in high and low cancer incidence strains of mice. a comparative study. 1979389688
[structure of drug resistant bacilli (author's transl)]. 1979390191
human plasma angiotensinogen: a review of purification procedures.the current status of the purification and characterization of human angiotensinogen is reviewed. one problem encountered in the past has been the copurification of a protein with similar porperties. this protein has tentatively been designated alanine-protein. an efficient separation of angiotensinogen and alanine-protein was obtained on a zinc chelate column. alanine-protein has been purified and its amino acid and carbohydrate composition determined. the cooh-terminal amino acid and the nh2-t ...1979390363
[cyclical nature and the prediction of the dynamics of the epidemic process in different types of dysentery]. 1979390937
patterns of shigella species and serotypes in east africa. 1979391541
[intestinal flora and bile acids metabolism -- influence of bile acids on rejection of shigella flexneri 2a from the intestine (author's transl)]. 1979392126
[effect of intercurrent pathology on the immune response of the child's body in dysentery]. 1979392428
[characteristics of the outbreak and control of an epidemic of bacillary dysentery of hydric origin].in december 1978, an unexpected outbreak of acute gastroenteritis occurred in a shoe factory. the clinical, epidemiological and laboratory investigations established the hydric origin of the dysentery due to shigella flexneri 3 a, caused by the illicit communication of the drinking water and industrial water mains. the antiepidemic measures promptly taken arrested the outbreak in three days ; there were no secondary, contact cases.1979394270
[studies concerning dysenteric infections in a closed children's community before and after antidysenteric vaccination. i. epidemiological considerations on acute intestinal infections].in the closed children's community studied between 1 jan. 1976 and 13 june 1977, a high proportion (54%) of the total number of acute intestinal infections was of dysenteric etiology, i.e. 46,9% in the 0--1 year age-group and 21,1% in the 1--3 years age-group, the dominant shigella subtype being represented by shigella flexneri 2a (25.1%). as only 37.2% of the total number of dysentery cases were manifested by enterocolitis and a high proportion (33.3%) ran a chronic course, the disease was not ...1979394271
lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (ippv) for 60 min. tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. the quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. immature animals with low lung-thorax complianc ...1979394314
[shigellosis in tananarive (madagascar). ii : bacteriologic and therapeutic features (author's transl)].in acute dysenteries or diarrhoeas shigellae are the bacterial organisms which are the most frequently isolated from coprocultures. the most frequent sub-group is sub-group b (s. flexniri). in vitro, shigellae are sensible to all antibiotics but often resistant to sulfamids. treatment is not difficult.1979395407
structural studies on the hexose region of the enterobacteriaceae type r3 core polysaccharide.the structure of the hexose region of the enterobacteriaceae type r3 core polysaccharide, which is the common core in shigella flexneri and some escherichia coli lipopolysaccharides (lps), has been investigated. the principal method used in these studies involved methylation analysis of the original and modified materials. the polysaccharide was modified by n-deacetylation-deamination and by smith degradation. as a result of these studies, the following structure is proposed: alpha-d-glcp-(1 lea ...1979371805
the effect of endotoxin-induced intraocular inflammation on the rat lens epithelium.intraocular inflammation induced by an intravitreal injection of shigella endotoxin into the rat eye produces early changes in the number of dividing cells of the lens epithelium and affects the organization of the meridional rows. a depression in mitotic activity in the germinative zone is observed during the first 24 hr after injection. at 48 hr, despite the continued mitotic inhibition in the germinative zone, an increase in cell division occurs in the central zone. by 72 hr, the germinative ...1979372124
[shigellosis]. 1979372830
[chimpanzee as a pet: cause of a shigella infection]. 1979372831
[properties of the r plasmids of sh. flexneri strains isolated in bulgaria].the study of 3,237 sh. flexneri strains isolated in bulgaria revealed that 50.72% of them were resistant to antibiotics. 95.88% of the antibiotic-resistant strains were found to have r factor of incompatibility groups f, i or n. the plasmids of incompatibility group f had the property fin+, and the plasmids of groups i and n had the property fin-. r plasmids were divided into 4 groups by their ability for phage restriction.1979373338
[comparative evaluation of different globulin preparations and of the means for blood sensitization in obtaining antibody erythrocytic diagnostica].in comparing the hemosensitizing activity of various immunoglobulin preparations with different methods of erythrocyte loading the greatest activity and specificity was revealed in igg isolated by means of deae-sephadex a-50. the method of erythrocyte sensitization with the use of alizarin blue indicator was more advantageous in respect to sensitivity and specificity of sh. sonnei and newcastle indication over boyden's, jandl and simmons', bing's methods.1979373342
[antibiotic resistance of shigella in different regions of the ussr].shigella were most sensitive to polymyxin ceporin, ampicillin, neomycin and furazolidone and resistant to chloramphenicol, tetracycline and streptomycin. shigella resistant simultaneously to two or three drugs mainly to tetracycline + chloramphenicol, tetracycline + streptomycin and tetracycline + chloramphenicol + streptomycin were most frequent. the frequency of the shigella strains carrying r-plasmids increased from 28 per cent in 1969--1970 to 72.6 per cent in 1977. the shigella strains isol ...1979373617
formation of a stable complex between human proelastase 2 and human alpha 1-protease inhibitor. 1979313930
relationship between blood flow velocity in the choroid and intraocular pressure in rabbits.by using thermistors for calorimetry to monitor blood flow velocity in the choroid of the anaesthetized rabbit, it was found that an elevation of intraocular pressure reduced the choroidal blood flow. the relationship between the ratio of perfusion pressure to intraocular tension (x) and the reciprocal value of the percentage of blood flow velocity (l/y) showed a curve convex towards the pressure axis. on a log-lin scale the graph was linear. a significant linear correlation with a coefficient o ...1979419976
skeletal changes in the condylar cartilage of the neonate mouse mandible.histological and histochemical qualitative and quantitative determinations are provided concerning the skeletal changes taking place in the growth center of the mandibular condyle in the neonatal icr mouse. this study followed the changes in both the major matrical components (collagen, acidic glycosaminoglycans and glycolipids) as well as in the various cartilage cells throughout the maturational period of the neonatal condyle. it was found that the transformation of neonatal condylar cartilage ...1979420892
projection from the vestibular nuclei to the inferior olive in the cat: an autoradiographic and horseradish peroxidase study.injections of horseradish peroxidase (hrp) in the inferior olive of 13 cats resulted in the labeling of neurons in the medial (mvn) and descending vestibular nuclei (dvn) as well as in subgroups g, p.h., s.v., x and z. the contribution of groups p.h. and z. could not be definitively established. injections of triated leucine in the vestibular nuclei and adjacent reticular formation in 4 cats indicated that the previously identified vestibular nuclei and subgroups project bilaterally to the dorso ...1979421137
the canine eye: the vessels of aqueous drainage.lumenal castings of canine vessels of aqueous drainage, prepared by microvascular injection of room-temperature vulcanizing silicone or batson's methacrylate corrosion compound no. 17, were viewed with a stereo dissecting microscope and by scanning electron microscopy. the pathways for aqueous drainage in the dog appear to extend radially from the interstices of the filtering meshwork, through the deep intrascleral venous plexus, to the midscleral venous circle of hovius, which also serves choro ...1979422328
high pressure liquid chromatographic determination of nitrofurazone in milk.a rapid high pressure liquid chromatographic (hplc) screening method for the quantitative determination of nitrofurazone in milk has been developed. the drug is extracted with ethyl acetate from a 2.0 ml milk serum sample, the organic layer is evaporated to dryness, and the residue is dissolved in the mobile phase and injected into the liquid chromatogarph. a reverse phase mubondapak c18 column is used with monitoring at 365 nm. the detection limit is 5 ppb and recoveries are 57--67%. mass spect ...1979422501
comparison of the membrane composition of spiroplasma citri and the corn stunt spiroplasma.components of membranes isolated from spiroplasma citri and corn stunt spiroplasma grown at 28 degrees c were analyzed. on a protein basis, lipid phosphorus was lower and cholesterol was higher in s. citri. only minor differences between the two species were found in fatty acid composition, reduced nicotinamide adenine dinucleotide diaphorase, and adenosine triphosphatase.1979422510
incidence and pathological features of spontaneous tumors in athymic nude mice.systematic observation of 1141 nude mice (swiss background [corrected] strain) that received human tumor transplants revealed 24 spontaneous tumors, 18 of lymphoreticular origin and 6 pulmonary adenomas. spontaneous tumors were seen at an average age of 9.1 months, and 22 of the tumors were seen only in that fraction of our group (324 mice) surviving for 5 months or more (22 of 324 x 100 = 6.8%). transplantation of these tumors to other nude mice was successful in three of five cases. mice trans ...1979427772
multi-element analysis of the rat hippocampus by proton induced x-ray emission spectroscopy (phosphorus, sulphur, chlorine, potassium, calcium, iron, zinc, copper, lead, bromine, and rubidium).a technique for multi-element analysis of brain tissue by proton induced x-ray emission spectroscopy (pixe) is described and data from analysis of fixed and unfixed samples from rat hippocampus, neocortex, amygdala, and spinal cord is presented and commented on. the atoms present in the tissue are bombarded with protons which causes the ejection of electrons from the inner shells. when the "holes" are refilled with electrons from outer shells, x-ray quanta characteristic for each element are emi ...1979429203
contribution of adrenal medulla, spleen and lymph, to the plasma levels of dopamine beta-hydroxylase and catecholamines induced by hemorrhagic hypotension in dogs. 1979438992
the problem of interaction of shigella with epithelial cells.a review and analysis of data on the investigation of factors concerning the initial events of interaction of shigella with epithelial cells: attachment of penetration are presented. in the experiments with 3h-labeled bacteria it was shown that although common pili confer adhesive properties to bacteria but the penetration of shigella into the cell is not increased. it was stated that lps of shigella o antigen plays an important role not only in interaction with cellular and humoral factors of t ...1979442880
carcinogenic hydrocarbons increase the acceptance of transfer ribonucleic acid for methionine. 1979444273
thermodynamics and kinetics of the interaction of copper (ii) ions with native dna. 1979444636
dissociations between the effects of lsd on behavior and raphe unit activity in freely moving cats.the hypothesis that the action of hallucinogenic drugs is mediated by a depression of the activity of brain serotonergic (raphe) neurons was tested by examining the behavioral effects of d-lysergic acid diethylamide (lsd) while studying the activity of raphe neurons in freely moving cats. although the results provide general support for the hypothesis, there were several important dissociations. (i) low doses of lsd produced only small decreases in raphe unit activity but significant behavoiral ...1979451617
studies on conformational changes in f-actin of glycerinated muscle fibers during relaxation by means of polarized ultraviolet fluorescence microscopy.by means of polarized ultraviolet fluorescence microscopy the conformational changes of f-actin occuring in glycerinated muscle fibers of rabbit and barnacle (balanus rostratus hock.) under the influence of adenosine triphosphate in the presence of ethylene glycol bis(beta-amino-ethyl ether)-n,n'-tetraacetic acid were discovered. these changes seem to be located near the surface of the globules thus hampering the penetration of univalent iones and neutral molecules into the f-actin macromolecule ...1979470613
[biomass accumulation by polyploid forms of candida guilliermondii yeasts].under the action of a mitotic poison (acenaphthene), the haploid culture of candida guilliermondii assimilating n-alkanes yielded a polyploid form whose cells were four times larger, on the average, than in the haploid culture. when the pure culture was grown under stationary conditions in media with glucose, the economical coefficient, i. e. the ratio between the assimilated glucose and the accumulated biomass, was by 16, 47 and 157% higher in the polyploid culture than in the haploid one after ...1979470627
[exopolysaccharide and proteolytic enzyme synthesis by m-, s- and r-forms of mycobacterium lacticolum].the composition of exocellular polysaccharides was studied in the m, s and r variants of mycobacterium lacticolum 104. the exoglycans of the m and s variants were found to be rather similar but differ considerably from the exoglycan of the r form. the polysaccharides of the m and s cells contained glucose, mannose, galactose, and pyruvic acid; the exoglycan of the r cells contained also the fourth sugar arabinose, but lacked pyruvic acid. the specific rotation of the polysaccharides from the m, ...1979470628
an xyy man.this case report describes a young man with a 47, xyy karyotype who was convicted of arson. he suffered from a cardiac disorder which may well have been part of the xyy syndrome rather than a chance association. his abnormal karyotype was disclosed in court and used by the defence in a plea in mitigation.1979497632
cellular aspects of muscle growth: myogenic cell proliferation. 1979500507
purification and chemical characterization of antigens from sheep erythrocytes.a mixture of glycoproteins and glycolipids was solubilized from sheep erythrocytes membranes under the effect of high ionic strength (2 m nacl, 0.5 m tris). several antigenic fractions could be purified from the mixture using gel filtration on sephadex g-200 and block electrophoresis on pevikon c870; two fractions were found to raise antibodies in a primary reaction and these antibodies effectively sensitized erythrocytes to lysis by complement. the majority of other fractions elicited a weaker ...1979511033
the preoptic region of the merino sheep. 1979511043
[first results obtained in man with ethinyl estradiol sulfonate given for various indications (proceedings)]. 1979515140
[serum enzymatic activity in acute injury to the renal parenchyma].studied was the activity of the serum enzymes lap, ce, aph, sph, and guanase as well as the isoenzymes of the unspecific esterases and aph in guinea pigs treated with potassium bichromate. morphologically and histopathologically, an acute injury of the kidney parenchyma was found, being in close correlation with the size of lesions and these enzymes' activity. the activity of aph, sph, and ce rose, and that of lap and guanase did not change. these enzymes proved to form an appropriate constallat ...1979516440
[allergenic and anaphylactoid properties of carcinostatic compounds of platinum].different effects of platinum salts on the organism were studied comparatively. the toxic effect was estimated by ld50; the carcinogenic one--by the action on ehrlich ascites tumor; the anaphylactoid effect was evaluated by the degree of the arterial pressure fall, the development of bronchospasm and an increased blood histamine level in cats under intravenous injection of platinum salts. the sensitization action of platinum salts was assessed on guinea pigs. all these effects are found to be de ...1979516565
[assimilation of certain amino acids administered to animals of different ages].changes in the content of some amino acids (tryptophane, lysine, histidine and arginine) in blood plasma were studied in young and old rabbits administered lysine, arginine and urea into the stomach. a decrease in utilization rate of the test amino acids in old animals, their interdependence and the effect of urea administration on the lysine level in blood serum at a relatively stable content of tryptophane and histidine were established. a conclusion is drawn about the necessity of taking into ...1979516594
[dry adapting additive and its use in dairy products for approximating the composition of human milk].the paper concerns a procedure for a new product, dry adapting additive (daa), designed for manufacture of liquid substitutes of breast milk under industrial conditions. the chemical composition of adapted milk mixtures is compared to that of breast milk. procedures for adapted mixtures to be manufactured at city milk kitchens, food concentrate factories and under domestic conditions have been developed, with the mixtures being widely tried on clinical basis.1979516610
histologic diagnosis of diseases of malabsorption.the diagnoses which may be arrived at by examination of peroral small bowel mucosal biopsy specimens are presented. celiac sprue, unclassified sprue (refractory sprue), infectious gastroenterititis, stasis syndrome and kwashiorkor have a severe mucosal lesion. other clinical conditions are required to establish the diagnosis in these diseases. a number of diseases have specific diagnostic features. included are whipple's disease, abetalipoproteinemia, collagenous sprue, primary intestinal lympho ...1979517556
the kidney and ochratoxin a. 1979520974
competition among hexoses for hepatocellular uptake in the perfused liver of rat [proceedings]. 1979521922
[on the stiffness of human tibialis anterior muscle during voluntary contraction (author's transl)]. 1979522295
the mast cell: iii. distribution and maturation in various organs of the young rat.the changing population-density of mast cells in various organs was plotted for rats aged 1/2 to 90 days and correlated with histochemical studies on the stage of maturation of cells. mast cells are present at birth in liver and spleen and are particularly associated with foci of haemopoiesis. in bone marrow mast cells are absent at birth but become progressively more numerous with increasing age of the animal. the association of mast cells firstly with foci of extramedullary haemopoiesis and se ...1979523184
[receptors of human red blood cells for anti-tah and anti-ahp in the course of intravascular aging].human o-erythrocytes aged in situ do not expose free receptors for anti-t agglutinin of arachis hypogea. new receptors for concentrated anti-a agglutinin of helix pomatia are manifested but are lost again in the course of further ageing of the cells in situ. a remasking of exposed receptors for anti-tah and anti-ahp byautologous, strongly binding globulins is supposed. these globulins could constitute the decisive signal for the autologous phagocytosis of senescent red blood cells.1979525143
reticulo-rumen motility in the chronically vagotomized sheep [proceedings]. 1979529098
adrenergic responses to transmural electrical stimulation of the guinea-pig gall-bladder [proceedings]. 1979529152
lipid metabolism in rats fed a diet with high citrus pectin content. 1979532387
[lodgement of the intraventricular catheter into cerebral parenchima in infantile hydrocephalus (author's transl)].ten cases of hydrocephalus of diverse ethiology, treated with ventriculo-peritoneal shunt are presented. in following controls it was observed that extreme of the catheter was located in cerebral parenchima. these features were followed of minimal clinics alterations and electroencephalographic focal manifestations. the pathogenesis of the complication due to the findings in the computerized axial tomography (cat) and the real value in the diagnosis of this complication are analized.1979533055
identification of a new allele of es-i segregating in an inbred strain of mice.a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.1979540008
effect of sodium hydroxide upon protein binding to filter paper disks and its significance in the determination of protein in colorimetric and radioisotopic assays. 1979543545
restoration of metabolic cooperation in heterokaryons between hgprt-deficient mouse a9 fibroblasts and chick embryo erythrocytes.genetic determinants of metabolic cooperation were studied by fusing chick erythrocytes to hgprt- mammalian cells. heterokaryons were then tested for their ability to incorporate [3h]hypoxanthine and to transfer radioactive material to hgprt- recipient cells. chick erythrocytes (ce) have nuclei which are inactive but contain the hgprt gene and some cytoplasmic hgprt enzyme activity. they are unable, however, to cooperate with hgprt- cells. of the two mammalian cell lines used, the human gm29 lin ...1979545717
convergence of human age-sex distributions to an equilibrium-state age-sex distribution. 1979545730
beta-[1-phenyl-5-bis(beta-chloroethyl)-amino-benzimidazolyl-(2)]-dl-alanine (zimet 3164): an immunosuppressant without marked anti-cancer effect.zimet 3164 inhibited the growth of sarcoma 180 p, sarcoma 180 g, and walker 256 carcinosarcoma, but was unable to prolong the survival time of mice bearing ehrlich ascites carcinoma or the leukaemias l 1210 and laj i to a worthwhile extent. the primary and secondarantly suppressed in mice. the drug exerted maximum effect when given on days--2 to +2 relative to antigenic stimulus. administration exclusively prior to immunization induced only moderate immunosuppression while injection afterwards f ...1979546175
some chemical and nutritional properties of acylated fish protein. 1979546957
correlation between gross observations of tumors and neoplasms diagnosed microscopically in carcinogenesis bioassays in rats.microscopic diagnoses of spontaneous and induced neoplasms in f344 rats in two carcinogenesis bioassays were correlated with the gross observations made at the time of necropsy. the results for a negative and a positive compound with reference to carcinogenicity, indicate that of the gross descriptions indicative of tumors, 37 percent and 24 percent respectively, were not diagnosed as neoplasms microscopically. however, some of the gross lesions were diagnosed histologically as nonneoplastic les ...1979547015
[lectins as reagents for the differentiation of serum enzymes. lectins as reagents, i. (author's transl)].lectins from canavalia ensiformis, phaseolus vulgaris, and triticum vulgare react with arylamidase, alkaline phosphatase, gamma-glutamyltransferase, and cholinesterase of human sera by formation of enzymatically active, mostly insoluble complexes. arylamidase, alkaline phosphatase, and cholinesterase react more intensely in sera of healthy people than in sera of patients with liver and neoplastic diseases. arylesterase is bound to a distinct degree only by concanavalin a. the enzymes mentioned a ...1979547035
[electron microscopical evidence of spiroplasma citri in nucleus of infected testplants (author's transl)].this is the first report for the evidence of mycoplasmas in an organelle of a plant cell. spiroplasma citri was detected by electron microscopy in the nucleus of a phloem parenchyma cell of chrysanthemum carinatum schousboe plants, inoculated experimentally by euscelis plebejus fall.1979549392
construction of haloaromatics utilising bacteria. 1979551259
aspartame: assessment of developmental psychotoxicity of a new artificial sweetener. 1979551307
postnatal behavioral changes in prenatally irradiated rats.rats were exposed on gestational day 15 to 125 r x-irradiation, a treatment known to severely alter brain morphology. at 4-6 weeks of age the behavior of these animals was studied using two methods: (1) measurement of circadian locomotor activity, (2) photographic analysis of behavioral acts. the circadian locomotor activity of irradiated rats was similar to that of controls tested individually or as groups in a residential unit. after morphine sulfate, 2 mg/kg, the increase in locomotor activit ...1979551312
studies on the inhibitory effects of zinc heptanoate on microorganisms.inhibitory effect of zinc heptanoate was observed on different cultures of bacteria and fungi. growth of all the bacteria was inhibited by the compound. greatest inhibition was seen in the case of staphylococcus albus, streptococcus pyogenes, shigella dysenteriae, shigella sonnei, shigella flexneri, salmonella typhi, s. paratyphi a, s. paratyphi b, vibrio cholerae, corynebacterium diphtheriae, and e. coli whereas least inhibition was found in the case of staphylococcus aureus. in triethanolamine ...1979553835
the relationship between genetics and environment in the pathogenesis of rheumatic diseases.major developments have taken place to further our understanding of the relationship between genetics and the environment in the pathogenesis of rheumatic disorders. the association between hla markers and human disease is becoming clearer. for instance, hla-drw4 frequently occurs in patients with rheumatoid disease, and penicillamine and gold toxicity are seen most often in patients with hla-drw2 or drw3. antisera to b alloantigens help define the genetic differences between systemic lupus eryt ...197918748470
measurement of functional capacity with visual analogue scales.the value of three visual analogue scales for measuring aspects of functional capacity was assessed in 22 patients with rheumatoid arthritis receiving long-term treatment. a scale in which patients were allowed to choose a function which was a particular problem gave the best results, with more severe initial impairment and greater change with treatment. this scale was as useful as pain in assessing the result of treatment.1979414343
[preclinical diabetes mellitus in children]. 1979414321
[roentgeno-morphologic changes in the bones of battered children].the demonstrated characteristic bone lesions should raise the suspicion of "battered child syndrome". the important role of the radiologist is stressed.19791457479
preventing the birth of a handicapped child. 1979243247
time in chemo-immunotherapy models: an absolute or a relative variable? lessons from the levamisole experience.an analysis is presented of the findings from the available studies in several cancer models, where 2.5-20 mg/kg levamisole was given in combination with different types of cytostatic drugs. it appears that in chemo-immunotherapy experiments it may be preferable to measure time variables (increase in life span, timing of chemotherapy and of immunotherapy) as a per cent of the median survival time of the untreated controls instead of using time as an absolute measure (in days). as regards the stu ...1980551097
time--a neglected aspect of psychiatric treatments.this review attempts to deal with the complex issues involved in the time to heal, with special reference to psychological processes. the questions of convalescence and relapse in organic medicine are explored and extrapolated to psychiatric processes. the concept of a latency period of change in treatment outcome is discussed with reference to both less complicated reactive states as well as highly charged neurotic processes. the problems of recognizing slow but perceptible change and separatin ...1980283799
children in cars. results of an observational study in new zealand.if children under the age of 14 years were adequately restrained while travelling in cars, many deaths and injuries could be prevented. seventeen thousand, one hundred and fifty-five children under 14 years of age were observed in cars. only 20 percent overall were appropriately restrained. a breakdown into different age groups showed that the percentage of children who were adequately restrained varied with ages: less than six months 54 percent; six months-four years 18 percent; five-seven year ...1980294525
mesothelioma on the coast of brittany, france. 1980294184
stimulation of prostaglandin e production by bacterial endotoxins in cultured human synovial fibroblasts.e coli, shigella, salmonella, and cholera endotoxins stimulated prostaglandin e (pge) production by cultured human synovial and foreskin fibroblasts. the minimal effective dose of shigella endotoxin was 2 micrograms/ml and a maximal response was observed at 10 micrograms/ml. pge stimulation was first detected 7 hours after addition of cholera endotoxin. stimulation by shigella endotoxin of both pge and hyaluronic acid production was inhibited by indomethacin and aspirin. the present results sugg ...19806157394
[change in the nonesterified fatty acid makeup of shigella flexneri no. 15172 type 3a in the process of passage on developing chick embryos].composition of nonesterified fatty acids/nefaj from shigella flexneri was similar to that from other gram-negative bacteria of the enteritic group. at the same time, nefa of the dysenteric bacteria contained comparatively high amount of branched and cyclopropane-bearing fatty acids. adaptation of shigella flexneri in the medium of developing chicken embryo led to a distinct increase in total nefa content as well as of cyclopropane-bearing and saturated fatty acids in the bacteria and to a decrea ...19806245536
genetic and physical evidence for plasmid control of shigella sonnei form i cell surface antigen.virulent shigella sonnei synthesize a surface antigen (form i) which appears to be one of several requirements needed for this host to invade epithelial cells. upon restreaking on agar media, form i cells readily and irreversibly generate form ii cells that lack the form i antigen. all form ii cells are avirulent. plasmid deoxyribonucleic acid of form i and ii cells of four different s. sonnei isolates, obtained from different areas of the world, was analyzed by agarose gel electrophoresis. a la ...19806249756
isolation of two protein-free and chemically different lipopolysaccharides from bordetella pertussis phenol-extracted endotoxin.endotoxin prepared from several bordetella pertussis strains in both immunological phases i and iv gave two lipopolysaccharide peaks (lps-i and lps-ii) when analyzed on hydroxylapatite columns in a phosphate buffer containing 0.1% sodium dodecyl sulfate; these lipopolysaccharides, present in the ratio of 2:3, are true endotoxins by both chemical and biological criteria. endotoxins isolated from escherichia coli, salmonella typhimurium, and shigella flexneri gave single lipopolysaccharide peaks w ...19806249793
neutron irradiation of bacteria in the presence and absence of secondary charged-particle equilibrium. 19806251509
[isolation and characteristics of polymyxin-resistant mutants of shigella flexneri].some characteristics of s. flexneri 2a mutants resistant to various concentrations of polymyxin m were studied. the data indicate that mutations resulting in low (50 microgram/ml) and high (300 microgram/ml) levels of the antibiotic resistance were determined by different genes. polymyxin resistance led to changed permeability of the outer membrane with respect to detergents and some antibiotics, such as aminoglycosides, penicillins, chloramphenicol and amphotericin b but did not change sensitiv ...19806252826
synthesis and utilization of siderophores by shigella flexneri.strains of shigella flexneri secrete a hydroxamate-type siderophore when grown in low-iron media. this hydroxamate appears to be identical with aerobactin, a siderophore synthesized by aerobacter aerogenes. in contrast to other enteric bacteria, s. flexneri did not produce detectable phenolate siderophores, although it could utilize an exogenously supplied phenolate.19806447691
[tendencies in the epidemic process of dysentery in ryazan].in shigellosis caused by sh. sonnei and sh. flexneri the epidemic process was found to have considerable difference in the tendencies and pace of its development. shigellosis which dominated in the etiological structure at the period following 1966 was dysentery caused by sh. sonnei; it showed the tendency towards a decrease in morbidity rate. dysentery caused by sh. flexneri was second in respect to the frequency of its occurrence after 1966 and showed the tendency towards increase. the simulta ...19806449121
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