Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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pernicious syndromes in plasmodium infections. | records of 560 male patients with plasmodium vivax and p. falciparum infection, who were admitted to a military hospital in the northeastern sector of india during the period from june, 1978, to june, 1980, have been analysed to establish the prevalence of pernicious syndromes. one hundred and seventy-eight patients (31.8%) had p. vivax malaria, 309 (55.1%) had p. falciparum malaria, and the remaining 73 (13.1%) were found to have mixed infection (p. vivax and p. falciparum). pernicious syndrome ... | 1982 | 6761563 |
inhibition by cyclosporin a of rodent malaria in vivo and human malaria in vitro. | the development and course of normally lethal parasitemias in mice inoculated intraperitoneally with erythrocytic stages of plasmodium yoelii or plasmodium berghei were markedly affected by treatment with the antilymphoid drug cyclosporin a (cs-a). when the first of four daily subcutaneous 25-mg/kg doses of cs-a was given at the time of parasite inoculation, patent infections failed to develop. if begun up to 5 days earlier, this same treatment regimen prolonged the prepatent period, attenuated ... | 1982 | 6752020 |
imported malaria in adults in auckland. | malaria is an increasing hazard of tropical travel. sixty-five cases were notified to the health department in 1980 and there is clear evidence of under notification. we reviewed the notes of 19 adults admitted to the infectious disease unit, auckland hospital, between 1 january 1979 and 31 march 1982. the typical patient admitted is a young caucasian new zealander presenting three months after returning from papua new guinea where he took prophylaxis: he is febrile, infected with p. vivax, has ... | 1982 | 6761610 |
[malaria--also a problem in our country]. | 1982 | 6761681 | |
comparison of in vitro pyrimethamine assays and in vivo response to sulphadoxine-pyrimethamine in plasmodium falciparum from papua new guinea. | the in vitro pyrimethamine sensitivity of 20 plasmodium falciparum isolates from papua new guinea children was determined. the children were treated with sulphadoxine-pyrimethamine and six were found to have clinically resistant malaria. the p. falciparum isolated from these subjects were more resistant to pyrimethamine in vitro than 13 of the isolates from sensitive cases. these results suggest that pyrimethamine sensitivity alone may be a good indicator of in vitro response to sulphadoxine-pyr ... | 1982 | 6761908 |
cultivation of fertile plasmodium falciparum gametocytes in semi-automated systems. 1. static cultures. | a semi-automated cultivation apparatus for the in vitro culture of plasmodium falciparum gametocytes is described. this apparatus has been designed to produce large numbers of fertile sexual stages for use in the development of a gamete vaccine or for the infection of suitable mosquitoes. these mosquitoes in turn may be used for the development of a possible sporozoite vaccine. loss of red cells during medium change has been eliminated and the addition of warmed fresh medium simplified compared ... | 1982 | 6761910 |
[current status of the physiopathology of pernicious malaria attacks]. | the understanding of the pathophysiology of cerebral malaria has much benefited from the modern techniques of in vitro cultivation of plasmodium falciparum and from a better knowledge of the biology of the parasite. the demonstration of the existence of "knob-like protrusions" explains some of the processes giving way to changes in the deep capillaries of viscera and particularly of brain. in a synthetic view one can say that this localized vasculopathy is the main factor of the pathologic chang ... | 1982 | 6755141 |
[a preliminary survey of sensitivity of plasmodium falciparum to chloroquine by in vitro microtechnic in china]. | 1982 | 6762283 | |
[drug resistance of plasmodium falciparum. analysis of factors in its appearance and spread]. | after recalling the biochemical and genetic mechanisms of p. falciparum chemo-resistance, the authors report on an analytic study of the factors ruling the apparition and diffusion of resistant strains. the phenomenon is of chromosomic origin. the repetitive and high doses of drugs exert a pressure on the strains which is the main factor for revealing the selecting resistant mutants. other facilitating factors may operate such as a lack of immunity of the considered population, a possible partic ... | 1982 | 6755142 |
[curative treatment of malaria plasmodium falciparum, p. vivax and p. ovale malaria with mefloquine]. | mefloquine (wr 142-490, ro 21.5998), and antimalarial 4-quinoleine-methanol, active on multiresistant strains of p. falciparum is a resourceful product because of its pharmacocinetics and the possibility it opens of a single day curative therapy. its mean half-live is 15 days, with important individual variations from 8 to 23 days as well as racial one within north-american, asiatic or african patients. a 1,25 to 1,50 g dose divided in 2 or 3 intakes during 16 hours has proved to be effective in ... | 1982 | 6755143 |
[chloroquine resistant falciparum malaria in east africa illustrated by a case of cerebral malaria]. | 1982 | 6762686 | |
[chloroquine resistant falciparum malaria in east africa]. | 1982 | 6762687 | |
a clinico--haematological profile of malaria. | 1982 | 6763036 | |
a preliminary survey of malaria in occidental, mindoro, philippines. | a survey of malaria in northwest mindoro, occidental, mindoro, philippines is reported. three species of human plasmodia were identified from 600 blood films examined. the overall prevalence of malaria was 7% (2.8% p. falciparum, 4.3% p. vivax, 0.7% p. malariae). the prevalence of malaria was highest (24%) among children 0 to 15 years of age and only 4 cases (12%) were found among persons over the age of 15. males and females were equally infected. study sites with the highest slide-positivity r ... | 1982 | 6755740 |
[autoimmune hemolytic anemia in plasmodium falciparum malaria in a cameroonese child]. | 1982 | 6763193 | |
red cell acetylcholinesterase activity in plasmodium falciparum malaria. | red cell ache activity was determined in 19 patients with p. falciparum malaria, 13 patients during convalescence as well as in 6 normal subjects. there was no significant difference between the mean values of ache in red cells of these 3 groups. after separation these blood samples into 2 portions by centrifugation in 5% ficoll solution, the parasitized red cells in the lower portion which are mostly ring forms contained the same amount of ache activity as those of the normal subjects and the n ... | 1982 | 6755742 |
evaluation of the antimalarial activity of the phenanthrenemethanol halofantrine (wr 171,669). | halofantrine (wr 171,669) was administered to 27 nonimmune subjects infected with the multi-drug resistant vietnam smith strain of plasmodium falciparum. it was also administered to three other subjects, one infected with the cambodian buchanan strain of p. falciparum, and two with blood-induced infection with the chesson strain of p. vivax. it cured infections with all three parasites. against the highly chloroquine-resistant smith strain, it was curative in single day treatment regimens. the d ... | 1982 | 6756175 |
studies on the role of red blood cell glycoproteins as receptors for invasion by plasmodium falciparum merozoites. | the mechanism of invasion of human red blood cells by plasmodium falciparum merozoites has been studied by several indirect methods. red blood cells of the s+s+u+ and s-s-u- blood group phenotypes were trypsin treated and their susceptibility to invasion measured. trypsin-treated s+s+u+ cells lack the portion of glycophorin a which bears the mn blood group determinants but possess glycophorin b, whereas trypsin-treated s-s-u- cells lack both the glycophorin a mn determinants and the glycophorin ... | 1982 | 6757749 |
malaria epidemiology and detectability. | conventional malaria surveys based on the microscopic examination of blood do not always detect chronic, low-grade infections caused by immunity. a model incorporating differences in detectability within the host population shows how the false negative tests caused by poor detectability confound measures of prevalence and the rates of infection and recovery. the model can also use multiple surveys on one group of individuals to estimate roughly the true prevalence. the form of data required is t ... | 1982 | 6758220 |
spring transmission of malaria in alwar region (rajasthan). | 1982 | 6759566 | |
the purification of gametocytes of plasmodium falciparum and p. yoelii nigeriensis by colloidal silica (percoll) gradient centrifugation. | percoll gradient centrifugation has been applied to plasmodium falciparum- and p. yoelii-infected blood to allow rapid concentration of gametocytes. in the case of cultured p. falciparum, stage iv and v gametocytes were separated from immature stage ii and iii forms and concentrated from initial gametocytaemias of 1 to 3% to an average of greater than 80% and a maximum of 100% purity in a fraction which collected at the 1.064/1.083 g/ml interface; the rounded gametocytes of p. yoelii-infected mo ... | 1982 | 6763789 |
haematological alterations in acute malaria. | in a study of 30 patients with either plasmodium or falciparum infection, 29 (97%) showed the presence of atypical lymphocytes in the peripheral blood film, 24 (80%) had thrombocytopenia and 17 (57%) had a mild to moderate anaemia. bleeding was encountered in 2 patients without confirmatory evidence of disseminated intravascular coagulation. | 1982 | 6753122 |
plasmodium falciparum: stage-specific lactate production in synchronized cultures. | 1982 | 6759150 | |
plasmodium falciparum: modifications of the in vitro culture conditions improving parasitic yields. | we attempted to optimize some of the variables involved in the in vitro culturing of plasmodium falciparum. irrespective of the isolates used, suspension cultures in glucose-enriched rpmi-1640 medium buffered with tes yielded about twice the amount of parasites than could be obtained from static, thin-layer cultures with hepes-buffered rpmi-1640 without additional glucose. in suspension cultures, methylcellulose (1 mg/ml) was added to protect the erythrocytes. in addition the erythrocytes were f ... | 1982 | 6757399 |
evaluation of cultured p. falciparum antigen in malaria indirect immunofluorescence test. | 1982 | 6764217 | |
clinical profile of malaria in eastern parts of india. | 1982 | 6764225 | |
[disseminated intravascular coagulation aa a complication of falciparum malaria]. | 1982 | 6764266 | |
[malaria in the municipality of humaitá, state of amazonas. xiii - use of clindamycin in the treatment of patients with plasmodium falciparum infection]. | 1982 | 6764284 | |
malaria at humaita county, amazonas state, brazil. xvi - gametocytes and lymphocytes studied in patients with plasmodium falciparum. | 1982 | 6764285 | |
[treatment of malaria (p. falciparum) with clindamycin. ii - dosage schedule for 5 days]. | 1982 | 6764286 | |
[resistance of plasmodium falciparum in the brazilian amazonas to the combination of sulfadoxine and pyrimethamine]. | 1982 | 6764287 | |
[in vivo resistance of plasmodium falciparum to the combination of sulfamethoxazole and trimethoprim in the brazilian amazonas]. | 1982 | 6764288 | |
malaria at humaita county, amazonas state, brazil. some aspects. | 1982 | 6764289 | |
[in vivo resistance of plasmodium falciparum to the combination of sulfadoxine and pyrimethamine, at riii level, in amazonas, brazil]. | 1982 | 6764290 | |
[acute kidney failure in plasmodium falciparum malaria]. | 1982 | 6764291 | |
study on clindamycin in the treatment of falciparum malaria. | 1982 | 6764292 | |
treatment of falciparum malaria with clindamycin. | 1982 | 6764293 | |
[the introduction of plasmodium falciparum into mediterranean europe: past and present]. | 1982 | 6764300 | |
[preliminary in vitro study of drug sensitivity of plasmodium falciparum in madagascar]. | 1982 | 6764607 | |
[preliminary study of the prevalence of malaria infestation in the province of tamatave]. | 1982 | 6764610 | |
[comparison of the results of indirect immunofluorescence reactions performed in the diagnosis of malaria using blood samples collected on filter paper and in capillary tubes]. | 1982 | 6764954 | |
a large-scale in vitro production system for plasmodium falciparum. | 1982 | 6757400 | |
epidemiology of plasmodium malariae infection in gambela, ethiopia. | malaria incidence and prevalence surveys were performed from december, 1967 to february, 1969 among the indigenous nilotic inhabitants of gambela, a small administrative centre in the western lowlands of ethiopia. entomological data suggested that malaria transmission was seasonal and this was consistent with monthly p. falciparum parasite rates. monthly p. malariae parasite rates, however, were consistent with an hypothesis of homogeneity. the age-specific incidence of quartan malaria among 26 ... | 1982 | 6765340 |
clinical studies on the treatment of malaria with qinghaosu and its derivatives. china cooperative research group on qinghaosu and its derivatives as antimalarials. | 1982 | 6765847 | |
clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives. | 1982 | 6765849 | |
epidemiology: malaria 1980. | 1982 | 6802318 | |
plasmodium falciparum malaria in nigerians who live in britain. | 1982 | 6802368 | |
plasmodium falciparum malaria in nigerians who live in britain. | 1982 | 6804003 | |
fatal falciparum malaria and the availability of parenteral antimalarial drugs in hospitals. | 1982 | 6805600 | |
delayed diagnosis of malaria. | 1982 | 6805629 | |
fatal falciparum malaria and the availability of parenteral antimalarial drugs in hospitals. | 1982 | 6805705 | |
review of data on susceptibility of mosquitoes in the ussr to imported strains of malaria parasites. | studies on the susceptibility of mosquitos in the ussr to imported species and strains of human malaria parasites have revealed that anopheles atroparvus, a. messeae, and a. sacharovi are highly susceptible to strains of plasmodium vivax from africa, asia, and south america. there was no significant variation in the level of adaptation to the various vector species.in experiments on infection of a. atroparvus and a. messeae with imported strains of p. falciparum from africa and southern asia, al ... | 1982 | 6761003 |
incipient resistance of plasmodium falciparum to chloroquine among a semi-immune population of the united republic of tanzania. 2. the impact of chloroquine used as a chemosuppressant on the immune status of the population. | decreased sensitivity and incipient resistance of plasmodium falciparum strains to chloroquine have been reported from mto-wa-mbu, in the north-east of the united republic of tanzania. in this locality the population had been exposed to chloroquine pressure for about two decades, in the form of medicated salt and through easy availability of the drug itself. in an attempt to find out whether such chemosuppression had influenced the immune response of the population, two seroepidemiological surve ... | 1982 | 6761004 |
quinine by intravenous infusion for falciparum malaria. | 1982 | 6809115 | |
chemoprophylaxis of malaria in africa: the spent "magic bullet". | 1982 | 6809183 | |
[hydroxypiperaquine phosphate in the treatment of falciparum malaria (author's transl)]. | 1982 | 6809276 | |
antimalarial activity of selected aromatic chelators. iii. 8-hydroxyquinolines (oxines) substituted in positions 5 and 7, and oxines annelated in position 5,6 by an aromatic ring. | 1982 | 6811856 | |
the treatment and control of parasitic diseases. | in many parts of world, transmission of malaria due to plasmodium falciparum can no longer be controlled by insecticides. furthermore, this species has developed an amazing capacity for resistance to polyvalent drugs. the advent of new drugs and the possibility of developing a vaccine offer some hope for control of falciparum malaria. the fact that the spread of many parasitic diseases is promoted by contaminated water supplies resulting from inadequate waste disposal raises important questions ... | 1982 | 6812199 |
dexamethasone deleterious in cerebral malaria. | 1982 | 6812711 | |
chemoprophylaxis of malaria in africa. | 1982 | 6812805 | |
chemoprophylaxis of malaria in africa. | 1982 | 6814658 | |
dexamethasone deleterious in cerebral malaria. | 1982 | 6814688 | |
[sero-immunologic diagnosis of malaria. methods and applications]. | 1982 | 6815403 | |
[qinghaosu and its derivatives]. | 1982 | 6815404 | |
malaria control and national health goals. report of the seventh asian malaria conference. | 1982 | 6815902 | |
plasmodium falciparum cultivation in vitro with fresh rabbit serum. | 1982 | 6817990 | |
prevention of malaria in travelers 1982. | 1982 | 6818450 | |
an evaluation of five regimens for the outpatient therapy of falciparum malaria in thailand 1980-81. | five regimens for the radical treatment of falciparum malaria were compared in five geographically separate areas of thailand. the cure rate for sulfadoxine-pyrimethamine was found to be low in the area of the kampuchean border and in the northeastern and western parts of the country. this distribution may be related to the spread of resistant parasites through the migration of labourers. a 7-day course of quinine was found to be uniformly effective, with an overall cure rate of 90% in these pri ... | 1982 | 6761005 |
efficient extraction and translation of plasmodium falciparum messenger rna. | a convenient method was employed for the efficient extraction of total rna from plasmodium falciparum. by depleting the total rna of trna, it was shown that p. falciparum or p. lophurae trnas markedly stimulate the translation of p. falciparum mrna in the rabbit reticulocyte cell-free system. analysis of the cell-free products revealed the presence of proteins well over 200 000 molecular weight, with the majority of polypeptides having high molecular weights. thus, this system can now be used to ... | 1982 | 6761590 |
evaluation of a crude soluble antigen from in-vitro culture of plasmodium falciparum for elisa. | the present study was to evaluate the soluble antigen prepared from the in-vitro cultured p. falciparum (fcr3) as an alternative source of antigen to those obtained from in-vivo models for enzyme linked immunosorbent assay (elisa) in serology of malaria. results obtained on known positive and negative reference sera revealed good correlation between the elisa and the indirect fluorescent antibody (ifa) technique (rs = 0.797; p less than 0.001). however such close correlation was not observed on ... | 1982 | 6761915 |
[clinical observations on pyronaridine phosphate by intravenous drip for the treatment of malaria]. | 1982 | 6762285 | |
a super mimic. a 71-year-old former native of new guinea presents with fever, diffuse rales in the chest and monocytosis. | 1982 | 6758740 | |
plasmodium falciparum: isolation and purification of spontaneously released merozoites by nylon membrane sieves. | 1982 | 6759149 | |
[resistance of plasmodium falciparum to fansidar, quinine and tetracycline]. | 1982 | 6762641 | |
plasmodium falciparum: automated assay of erythrocyte invasion using flow cytofluorometry. | 1982 | 6807707 | |
effects of ca++ depletion on the asexual cell cycle of plasmodium falciparum. | ca++ was shown to be indispensable for the normal growth of cultures of plasmodium falciparum. inclusion of ethyleneglycolbis (beta-amino-ethylether) n,n'-tetra-acetic acid (egta) caused blocking of the asexual cell cycle of the parasite in two sites, the first blockage occurring between 20 and 26 hours after invasion of the erythrocyte. it proved to be irreversible by additions of mg++ or ca++, and to lead to morphologically abnormal parasites arrested in the mature trophozoite stage of the cyc ... | 1982 | 6808848 |
highlands malaria: malaria in enga province of papua new guinea. | malaria is endemic in valleys below 1600m in enga province of the highlands of papua new guinea. however because malaria is unstable in character and levels of transmission fluctuate, endemicity cannot be precisely categorized. falciparum malaria epidemics are lethal here and malaria is an important disease among the people dwelling below 1600m. possibly because of this most of the population live above 1600m where malaria transmission is less likely. in some areas however malaria may be transmi ... | 1982 | 6764076 |
chloroquine and quinine resistant plasmodium falciparum on the island of mindoro, philippines, 1982. | a field study was conducted on the island of mindoro, republic of the philippines in which over 800 persons were screened for malaria and approximately 8% were found positive. the in vitro microtechnique was used to test for sensitivity to chloroquine, amodiaquine, mefloquine and quinine in 20 slide-confirmed p. falciparum cases. sixteen of these cases were also followed for in vivo chloroquine sensitivity. four cases showed in vitro resistance to chloroquine; 2 also showed resistance to quinine ... | 1982 | 6763355 |
serum quinine concentrations following the initial dose in children with falciparum malaria. | serum quinine concentrations were determined in 51 children with uncomplicated falciparum malaria and 22 controls. quinine 10 mg salt/kg was given one-hour, two-hour, four-hour intravenously in group a (14 patients, 5 controls), group b (12 patients, 6 controls), group c (10 patients, 6 controls) and given orally in group d (15 patients, 5 controls). in malaria patients, the highest serum quinine levels were observed at the end of intravenous infusion and by the 4th hour after oral medication. m ... | 1982 | 6763356 |
the effect of soluble glycophorin a on invasion of human red cells by the malarial parasite plasmodium falciparum. | 1982 | 6763358 | |
about the concept of malaria as a disease. | 1982 | 6765339 | |
[malaria in pregnant women. presentation of 2 cases and review of the literature]. | 1982 | 6763616 | |
cerebral malaria in children: a retrospective study of admissions to madang hospital, 1980. | a review was undertaken of sixty-eight children admitted with cerebral malaria to madang hospital, madang, papua new guinea (png) in 1980. children with cerebral malaria were significantly older than those with uncomplicated malaria, and older than children admitted with other conditions causing fits or coma. the nutritional status of children with cerebral malaria did not differ from that of children admitted with other diagnoses. the cerebrospinal fluid was normal in 80% of children with cereb ... | 1982 | 6764075 |
diminished red blood cell deformability in uncomplicated human malaria. a preliminary report. | six patients with active p. falciparum malaria (two resistant to chloroquine therapy), one with treated and apparently cured p. falciparum malaria, one with active p. vivax malaria and two controls from the same geographic area of amazonian brazil were studied. all malaria patients had impaired red cell deformability. this was not correlated with drug resistance or number of parasitized cells. the hypothesis is presented that the presence of parasites in red blood cells and related metabolic eff ... | 1982 | 6763070 |
marker enzymes of plasmodium falciparum and human erythrocytes as indicators of parasite purity. | plasmodium falciparum trophozoites, isolated by mechanical rupture of infected human erythrocytes, were analyzed for purity by determination of the specific activities of a number of marker enzymes selected for high activity, stability, and convenience of assay procedures. the specific activities of the soluble enzymes lactate dehydrogenase and malate dehydrogenase were much higher in the parasite than in the erythrocyte. the soluble enzyme glutamate dehydrogenase (nadp+) was specific for the pa ... | 1982 | 6757398 |
placental pathologic changes in malaria. a histologic and ultrastructural study. | placenta malarial changes (pmcs) related to maternal plasmodium infection were present in 33% (247 cases) of a series of 741 placentas collected from an unselected population living in an area of high malarial endemicity (haut-ogooué, gabon, africa). plasmodia were found on material thick blood films taken at the time of delivery in 42% of the women with and 24% of women without associated pmcs. plasmodium falciparum was the most frequent infecting organism. pmcs were more frequent and, in gener ... | 1982 | 6758604 |
plasmodium falciparum: rapid assay for in vitro inhibition due to human serum from residents of malarious areas. | 1982 | 6759151 | |
[plasmodium falciparum malaria transmitted through human contact in a group of drug addicts]. | the authors describe a case of malaria from p. falciparum occurred in a group of young drug-addicts. noteworthy is the fact that such a way of transmission did never occur before in italy. current concepts in treatment of malaria are briefly reviewed. | 1982 | 6757799 |
susceptibility of anopheles gambiae to plasmodium yoelii nigeriensis and plasmodium falciparum. | 1982 | 6763502 | |
transfusion malaria: treatment with exchange transfusion after delayed diagnosis. | a 65-year-old woman was rehospitalized for increasing mental confusion 16 days after open heart surgery for mitral stenosis. a diagnosis of transfusion-acquired falciparum malaria was made from a routine peripheral blood smear 24 hours after admission. because progressive encephalopathy developed while she was receiving antimalarial drugs, a therapeutic exchange transfusion was performed. clinical improvement occurred promptly during the exchange, and the patient went on to complete recovery fro ... | 1982 | 7032444 |
dexamethasone proves deleterious in cerebral malaria. a double-blind trial in 100 comatose patients. | high-dose dexamethasone was compared with placebo in a double-blind trial involving 100 comatose patients with strictly defined cerebral malaria. the two treatment groups, whose members were six to 70 years old, proved comparable on admission. there were eight deaths in the dexamethasone group and nine in the placebo group (no significant difference; p = 0.8); at post-mortem examination the brain showed features diagnostic of cerebral malaria in all but one patient who died. dexamethasone prolon ... | 1982 | 7033788 |
preliminary studies of the response of plasmodium falciparum to chloroquine in nazareth town, central ethiopia. | 1982 | 7032907 | |
malaria at groote schuur hospital, 1976-1980. | twenty-seven patients with malaria were treated at groote schuur hospital between 1976 and 1980. only 2 patients had taken adequate prophylactic agents. although the incidence of complications was high, no deaths occurred. it is anticipated that the number of cases of malaria seen in cape town will increase and a high index of suspicion about malaria among clinicians is urged. | 1982 | 7036378 |
lysis of plasmodium falciparum by ferriprotoporphyrin ix and a chloroquine-ferriprotoporphyrin ix complex. | ferriprotoporphyrin ix (fp) and a chloroquine-fp complex lysed isolated plasmodium falciparum parasites as judged by decreases in the turbidity of parasite suspensions and by ultrastructural changes. exposure of parasite suspensions to 50 microm fp or to a complex formed from 50 microm fp and 20 microm chloroquine reduced the number of identifiable parasites and caused swelling and loss of internal detail in those that were identifiable. the amount of lysis was dose-dependent over the range of 1 ... | 1982 | 7049079 |
the direct antiglobulin test in p. falciparum malaria. | the direct antiglobulin test (dat) was performed on 134 gambian children with p. falciparum malaria. 52 children had a positive dat and in 25 this was due to the adherence of c3 to their red cells whilst 13 had sensitization with igg as well as c3. sensitization with c4 alone or associated with igg and/or c3 was only rarely found. the haemoglobin levels and reticulocyte counts were not significantly different in patients with a positive dat from those with a negative dat. the children with posit ... | 1982 | 7049218 |
[epidemiological and clinical features of malaria in two villages of the lékié division (cameroon)]. | the examination of the thick drops shows malaria parasites in 20,8% of the slides in minkama and nalassi: 95,7% of those slides are positive for p. falciparum and 4,3% for p. malariae. the parasite rate, representing the percentage of children up to 9 years of age showing parasites in their blood, is 42,2%. using the immunofluorescent test, antibodies are found in 43,7% of the blood samples in the study area. in the hospital, 51% of the patients with malaria are 0 to 4 years old children. the cl ... | 1982 | 7049427 |
[three cases of malaria induced by blood transfusion]. | 1982 | 7049428 | |
circumsporozoite proteins of human malaria parasites plasmodium falciparum and plasmodium vivax. | monoclonal antibodies were raised against sporozoites of two species of malaria parasites, plasmodium falciparum and plasmodium vivax. the antibodies reacted with polypeptides (circumsporozoite proteins) that are uniformly distributed over the entire surface of sporozoites, as shown by indirect immunofluorescence and by the circumsporozoite precipitin reaction. the epitopes recognized by the monoclonal antibodies were expressed on sporozoites from different geographical isolates of the homologou ... | 1982 | 7045272 |
erythrocyte - endothelial cell adherence in sickle cell disease, diabetes mellitus, and falciparum malaria: adverse effects reversed with piracetam. | the erythrocytes of patients with sickle hemoglobin, diabetes, and falciparum malaria adhere disproportionately to endothelial cells. such pathophysiological activity compromises the microcirculation and results in clinical disease. since piracetam (2-oxo-1 pyrrolidine acetamide) has been shown to have a number of clinically beneficial actions on the formed elements of the blood including disengagement of adherent diabetic and sickle erythrocytes there is a rational basis for the trial of pirace ... | 1982 | 7045599 |
target antigens of purified human immunoglobulins which inhibit growth of plasmodium falciparum in vitro. | 1982 | 7045680 |