Publications

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adrenocorticotropin stimulation of cyclic adenosine 3', 5'-monophosphate formation in isolated rat adrenal cells. the role of membrane sialic acid. 19744371307
fusion of chicken erythrocytes by phospholipase c (clostridium perfringens). the requirement for hemolytic and hydrolytic factors for fusion. 19744371392
fusion of intact human erythrocytes and erythrocyte ghosts.sendai virus is able to induce the fusion of human erythrocytes. bivalent cations or atp are not essential for polyerythrocyte formation. high fusion indices were obtained when sendai virus was added to cells incubated in the presence of both edta and iodoacetic acid. human erythrocyte ghosts prepared by gradual hemolysis still retain the potential to undergo virus-induced fusion. fusion of human red blood cells without the addition of viruses was obtained by incubation of erythrocytes at ph 10. ...19744371393
cyclopenta(f)isoquinoline derivatives designed to bind specifically to native deoxyribonucleic acid. 3. interaction of 6-carbamylmethyl-8-methyl-7h-cyclopenta(f)isoquinolin-3(2h)-one with deoxyribonucleic acids and polydeoxyribonucleotides. 19744371416
netropsin. a specific probe for a-t regions of duplex deoxyribonucleic acid. 19744371420
the role of platelet membrane phospholipids in the platelet release reaction.the structure and function of the platelet surface was probed by phospholipase c (clostridium perfringens) which hydrolyzes membrane phospholipids, particularly phosphatidylcholine. platelet phospholipids were susceptible to phospholipase c, and extent of hydrolysis was dependent on concentration of phospholipase c and ca(++). phospholipase c (0.15 u/ml) with ca(++) (0.55 mm) hydrolyzed 15.6% phospholipids during 5 min. phospholipase c released platelet serotonin (5ht), adp, and platelet factor ...19744371563
the role of clostridium perfringens in the growth response of chicks to dietary penicillin. 19744371566
bilirubin udp-glucosyl-and udp-glucuronosyltransferase of rat liver. a comparative study of the effects of membrane perturbants in vitro and of chrysene administration in vivo. 19744371579
a method for the detection of starch hydrolysis by bacteria. 19744371640
clostridium perfringens in the environment.clostridium perfringens was isolated from samples collected in puget sound in the state of washington and areas considered as possible sources of these organisms to puget sound. the distribution of c. perfringens in the total clostridium population was determined for fish gut contents and sediments collected in highly polluted and less polluted areas, sewage samples, freshwater sediments, and soils. the greatest numbers of c. perfringens were obtained from marine sediments collected near the sew ...19744371684
autoxidation as a cause of antibacterial activity in unsaturated fatty acids. 19744371778
the effect of phospholipase on the binding of asialoglycoproteins by rat liver plasma membranes. 19744371836
biosynthetic pathways and turnover of individual biliary phosphatidylcholines during metabolism of (1,1-2h2)ethanol in the rat. 19744371838
biosynthesis of molecular species of phosphatidylcholines in bile, liver and plasma of rats given (1,1-2h2)ethanol. 19744371839
isozymes of human alpha-l-fucosidase detectable by starch gel electrophoresis. 19744371999
necrotic enteritis in broiler chickens. ii. pathology and proposed pathogenesis.the intestines from 124 dead, sick and normal broiler chickens from 24 cases of necrotic enteritis were subjected to histological examination. tissue sections from the duodenum, jejunum, ileum and ceca from each broiler were examined histologically for lesions of necrotic enteritis and the presence of coccidia. lesions of necrotic enteritis were present in one or more areas of the intestine in all but six of 94 dead or sick birds and they were most common and severe in the jejunum. coccidia were ...19744373152
sporulation and enterotoxin production by clostridium perfringens type a under conditions of controlled ph and temperature. 19744373153
[aerotolerant mutant of c. perfringens a (author's transl)]. 19744373176
[phospholipases of bacterial origin (author's transl)]. 19744373177
[studies on the problem of growth of seperated microorganisms on glass-fiber fine-dust and glass-fiber high-capacity-floating-particle filters]. 19744373308
[clostridium perfringens sepsis]. 19744373315
a new medium for the detection and enumeration of clostridium perfringens in foods. 19744373426
activation of hexose transport by concanavalin a in isolated brown fat cells. effects of cell surface modification with neuraminidase and trypsin on lectin and insulin action. 19744373470
improved culture techniques and sporulation medium for enterotoxin production by clostridium perfringens type a. 19744373517
characteristics of enterotoxigenic clostridium perfringens type a isolated from cattle and chickens. 19744373518
[necrotizing ethmoiditis caused by anaerobic bacteria. apropos of a case]. 19744373521
formation of phospholipase c and theta-haemolysin in pre-reduced media in batch anc continuous culture of clostridium perfringens type a. 19744373522
the use of subzero temperatures in biochemistry: slow reactions. 19744373636
[therapy of gas gangrene. comparison of results of the standard and hyperbaric oxygen therapy (author's transl)]. 19744373643
clostridium perfringens (cl. welchii) in the human gastro-intestinal tract. 19744373836
serum albumin alterations during experimental sepsis. 19744373849
[experimental investigations in guinea pigs on the therapy of gas gangrene with ozone. a preliminary report (author's transl)]. 19744373940
[physiological role of polynucleotide phosphorylase]. 19744373979
recovery of heated clostridium perfringens type a spores on selective media.the enumeration of clostridium perfringens spores on sulfite-polymyxin-sulfadiazine agar (sps), tryptone-sulfite-neomycin agar (tsn), shahidi-ferguson-perfringens agar (sfp), tryptone-sulfite-cycloserine agar (tsc), and tsn lacking antibiotics (base) was studied. the spores were heated at 105 to 120 c by the capillary-tube method. the media were about equally efficient for the enumeration of heat-activated spores. efficiency of the media for the recovery of spores surviving heat treatments at ul ...19744374120
cold shock lethality and injury in clostridium perfringens.several observations have been made in regard to cold shock lethality of clostridium perfringens: (i) loss of viability was not consequence of exposure of the cells to air; (ii) stationary-phase cells were much more resistant to cold shock at 4 c than exponential-phase cells; (iii) at 4 c 96% of an initial population of exponential-phase cells was killed upon cold shock and 95% of the remaining population was killed within 90 min of continued exposure at 4 c; (iv) the minimal temperature differe ...19744374121
response of ligated intestinal loops in chickens to the enterotoxin of clostridium perfringens.approximately 45-cm length of jejunoileum of 7-week-old chickens was found to be responsive and suitable for testing the enterotoxin of clostridium perfringens by the ligated intestinal loop technique. injections of 20 to 30 mug of enterotoxin per loop caused positive response of fluid accumulation. chickens were found to be more convenient and economical for this purpose than other laboratory and domestic animals.19744374124
clostridium perfringens in hospital patients. 19744374433
fecal clostridium perfringens and rheumatoid arthritis. 19744374477
[clostridium perfringens. (3). its distribution in food and serotypes]. 19744374478
[the effect of the agents of anaerobic gas infection on human granulocytes]. 19744374643
[gas gangrene. etiologic clinical and current therapeutic aspects]. 19744374685
extracellular deoxyribonuclease production by anaerobic bacteria.the production of extracellular deoxyribonuclease was examined with anaerobic organisms isolated from clinical specimens. nuclease activity was extraordinarily common. all strains of fusobacterium, including eight species, as well as bacteroides fragilis and b. melaninogenicus, displayed enzyme activity. whereas the gram-positive bacteria were generally less productive, all strains of clostridium perfringens, peptostreptococcus intermedius, and p. anaerobius specifically produced deoxyribonuclea ...19744364608
effect of culture medium and carbon dioxide concentration on growth of anaerobic bacteria commonly encountered in clinical specimens.representative strains of anaerobic bacteria from human infections were used to evaluate broth media, gas mixtures, and inocula for use in developing a procedure for performing minimal inhibitory concentration antimicrobic susceptibility tests. nine commercially available media, including two that were chemically defined, were tested. tests were performed in atmospheres with carbon dioxide concentrations between 2.5 and 10% and also in the gaspak system (bbl) that had a disposable hydrogen-carbo ...19744364610
identification of iduronic acid as a constituent of the "type-specific" polysaccharide of clostridium perfringens hobbs 10. 19744364631
isolation and relationship of human hexosaminidases. 19744364658
the mode of action of metronidazole in trichomonas vaginalis and other micro-organisms. 19744364702
recent dna fiber diffraction studies and their implications for dna recognition. 19744364787
a method for the preparation of desialylated human chorionic gonadotropin and its sub-units. 19744364844
properties of antisera to ganglioside gm1 and asialo gm1. 19744364954
increase in gross (g) antigen sites on the surface of akr virus-induced rat lymphoma cells after treatment with trypsin. 19744364955
[the effect of molecular oxygen on anaerobic bacteria of the genus clostridium]. 19744363859
plasma membrane ectoglycosyltransferase activity of l1210 murine leukemic cells. 19744363882
use of a concanavalin a polymer to isolate right side-out vesicles of purified plasma membranes from eukariotic cells. 19744363943
[the mechanism of anaerobic gastrointestinal infection in man]. 19744363982
[gas gangrene treated with hyperbaric oxygen]. 19744363989
[editorial: gas gangrene]. 19744363990
sialic acid residues exposed on mammalian cell surface: the effect of adsorption of denatured virus particles. 19744364005
protein-bound carbohydrate content of normal and tumorous human lung tissue. 19744364129
studies of the metabolism of asialotransferrins: potentiation of the catabolism of human asialotransferrin in the rabbit. 19744364133
rat brain microsomal gangliosides. accessibility to a neuraminidase preparation and the possible existence of different pools in relation to their biosynthesis.1. treatment of rat brain microsomal membranes with a neuraminidase preparation from clostridium perfringens resulted in an almost complete conversion of polysialogangliosides into monosialogangliosides. 2. neuraminidase treatment of the membranes did not increase the incorporation of n-[(3)h]acetylneuraminic acid from cmp-n-[(3)h]acetylneuraminic acid into the gangliosidic fraction, indicating that a monosialoganglioside is an acceptor of n-acetylneuraminic acid in these membranes only if, in a ...19744362745
mesophilic clostridia in puget sound. 19744362754
biliary infections and the chouce of antibiotics. 19744369806
blastocystis hominis: axenic cultivation. 19744369819
clostridial myonecrosis of the abdominal wall. management after extensive resection. 19744369868
clostridium perfringens type c in hemorrhagic enterotoxemia of neonatal calves in alberta. 19744369869
acute emphysematous cholecystitis.acute emphysematous cholecystitis is an uncommon condition caused by gas-forming organisms and characterized by the presence of gas in the wall and lumen of the gallbladder. its incidence is higher among male diabetics. aec in an elderly north american diabetic man with indian ancestry is reported with a brief review of the world literature. the diagnosis was made preoperatively with the aid of plain radiographic films of the abdomen. a gangrenous distended gallbladder was removed at operation. ...19744429938
microbiological agar diffusion assay for metronidazole concentrations in serum.an agar diffusion method using paper disks on plates seeded with clostridium perfringens and incubated anaerobically to assay serum levels of metronidazole is described. the lowest serum metronidazole concentration that could be measured was 0.7 mug/ml, and the average error was 4% for 5 mug/ml. this assay could measure metronidazole in the presence of gentamicin or in the presence of penicillin, with the use of penicillinase incorporated into the assay plates, or in presence of penicillin, meth ...19744462462
[phospholipase c-induced release reaction in platelets (author's transl)]. 19744375036
relation of enterotoxigenic clostridium perfringens type a to food poisoning. i. effect of heat activation on the germination, sporulation and enterotoxigenesis of c. perfringens. 19744375169
reinvestigations of the relationship between sporulation, heat resistance and some biochemical properties in strains of clostridium perfringens. 19744375194
sedimentation of bacteria with polyethylene glycol. 19744375273
bacteriological control in the processing of poultry. 19744375341
genetic control of serum esterases in day-old pigs. 19744375416
brain oedema: an experimental model. 19744375484
[dna-ribonuclease associations. ii. conformational study]. 19744375492
ionic germination of spores of clostridium perfringens type a. 19744375727
[coliform bacteria and escherichia coli in marketed fruits and vegetables]. 19744375784
in vitro effect of metronidazole and tinidazole on anaerobic bacteria. 19744375789
[pathomorphologic changes in animals with experimental gas infection immunized with cl. perfringens and oedematiens toxoids]. 19744375917
[morphological and histochemical changes caused by clostridial toxins in chick embryo fibroblast cultures]. 19744375920
[effectiveness of cephalosporins in experimental anaerobic gas infection]. 19744375943
comparative effect and fate of non-entrapped and liposome-entrapped neuraminidase injected into rats.non-entrapped and liposome-entrapped clostridium perfringens neuraminidase (0.5-0.6 unit) was injected into rats and its fate as well as its effect on plasma and erythrocyte n-acetylneuraminic acid was investigated. the following observations were made. (1) although removal of both non-entrapped and liposome-entrapped neuraminidase from the circulation was completed within 5h after injection, their recovery in tissues was distinctly different; 7-10% of the injected non-entrapped enzyme was found ...19744375965
pyridoxal phosphate-sensitized photoinactivation of glutamate decarboxylase from clostridium perfringens.1. l-glutamate decarboxylase (ec 4.1.1.15) from clostridium perfringens was inactivated by exposure to visible light at ph6.2. 2. inactivation does not occur at ph4.6 or in the absence of bound pyridoxal phosphate. 3. on prolonged photo-oxidation six histidine residues per molecule of enzyme were destroyed. 4. the loss of six cysteine residues per molecule occurred both in irradiated samples and in controls oxygenated in the dark. 5. this dark-oxidation of cysteine residues is apparently require ...19744375980
the effect of specific glycosidase treatment on the responsiveness of lymphocytes. i. response of human lymphocytes to concanavalin-a. 19744376056
the mechanism of action of soluble lymphocytic mediators. ii. modification of macrophage migration and migration inhibitory factor action by drugs, enzymes and cationic environment. 19744376058
effect of heat activation on biomorphics, hemolysis and lecithinase activity of clostridium perfringens type a. 19744376076
recent changes in bacterial resistance to antibiotics. 19744376234
[hepatic and subphrenic abscess and septicemia caused by w. perfringens without hemolysis or anuria]. 19744376271
[specific prophylaxis of anaerobic enterotoxemia in calves]. 19744376294
[recent developments in the diagnosis of bacterial food intoxications (author's transl)]. 19744376320
the significance of tissue gas and clostridial organisms in the differential diagnosis of gas gangrene. 19744376414
conformation and reactivity of dna. vi. circular dichroism studies of salt-induced conformational changes of dnas of different base composition. 19744376422
[effect of experimental anaerobic intoxication on the heart bioelectrical currents (according to eeg data]. 19744376740
proteases as mitogens. the effect of trypsin and pronase on mouse and human lymphocytes. 19744372074
studies of the insulin-like actions of polyamines on lipid and glucose metabolism in adipose tissue cells. 19744372216
susceptibility tests of anaerobic bacteria: statistical and clinical considerations. 19744372272
effect of a lactobacillus product administration on the anaerobic intestinal flora of aged adults. 19744372432
gas gangrene-on the basis of 19 observations. advantages of combining surgery with hyperbaric oxygen therapy. 19744372493
fluorescent antibody inhibition for determination of serum antibodies against the enterotoxin of clostridium perfringens type a. 19744372662
emphysematous cholecystitis--an important clinical variant of acute cholecystitis. 19744372674
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