Publications

plasma adh increase and thirst suppression elicited by preoptic heating in the dog.		1974	4809877
letter: hepatorenal syndrome and prolactin.		1974	4810128
cholera toxin: interaction of subunits with ganglioside gm1.	vibrio cholerae exotoxin is an aggregate of two different noninterconvertible subunits (molecular weights about 15,000 and about 25,000). only the smaller subunit reacts with ganglioside g(m1), a possible biological receptor. the larger subunit, found only in active toxin molecules, can be eluted with 8 molar urea from insoluble complexes of toxin, ganglioside, and cerebroside.	1974	4810267
effect of 2-br-alpha-ergocryptine on pituitary synthesis and release of prolactin and growth hormone in rats.		1974	4810405
an analysis of d-amphetamine produced facilitation of avoidance acquisition in rats and performance changes subsequent to drug termination.		1974	4810494
gas chromatographic analysis of methomyl residues in soil, sediment, water, and tobacco utilizing the flame photometric detector.		1974	4811638
the enzymatic desulfation of sulfated sugar nucleotides by a novel sulfatase in hen oviduct.		1974	4811905
[current problems of el tor cholera].		1974	4815452
metabolic differences in bacillus stearothermophilus grown at 55 degrees c and 37 degrees c.		1974	4815911
letter: addendum to response of man to infection with vibrio cholerae.		1974	4817466
active specific immunotherapy of minimal residual tumor: excision plus neuraminidase-treated tumor cells.		1974	4818273
[cholera ante portas].		1974	4818887
sensitization and centre-surround antagonism in necturus retina.	1. the impulse discharge of ganglion cells and the proximal negative response were recorded with extracellular micro-electrodes in necturus retina and spatial influences of background illumination studied.2. when a steady background of constant illuminance was extended in diameter from 0.25 to 1 mm, the response to a small concentrically placed test flash was enhanced (sensitization).3. this sensitization was tonic, showed marked spatial summation, was also found by surrounding a central backgro ...	1974	4822576
adult-litter relations in rats reared in single and dual-chambered cages.		1974	4822843
antibody responses in rabbits to injections of whole cell, flagella, and flagellin preparations of cholera and noncholera vibrios.	sera prepared by the injection of living cells, killed cells, flagella, or flagellins of vibrios into rabbits were examined for antibodies which cross-reacted with cholera and noncholera vibrio strains. antisera to vibrio cholerae strains agglutinated heterologous v. cholerae strains. they did not agglutinate strains of noncholera vibrios. sera to noncholera strains agglutinated homologous strains only. there was no evidence that a common antigen was present in the organisms tested. the proposal ...	1974	4823423
evaluation of thiosulfate-citrate-bile salts-sucrose agar, a selective medium for the isolation of vibrio cholerae and other pathogenic vibrios.		1974	4823581
delta9-tetrahydrocannabinol: subcortical spike bursts and motor manifestations in a fischer rat treated orally for 109 days.		1974	4823985
current status of cholera in maharashtra.		1974	4824271
psychotomimetics as anticholinergic agents. i. 1-cyclohexylpiperidine derivatives: anticholinesterase activity and antagonistic activity to acetylcholine.		1974	4824775
vascular leakage through intraendothelial channels induced by cholera toxin in the skin of guinea pigs.	guinea pigs were injected intravenously with evans blue solution (1/2), 1, 5 and 22 hours after intradermal injection of vibrio cholerae 569b toxin. then they were fixed by perfusion with diluted karnovsky's aldehyde mixture 1(1/2), 5, 10, 15 and 90 minutes later. in some cases, horseradish peroxidase was mixed in the dye solution, and chopped tissue slices were incubated histochemically. dermal blood vessels from these samples were examined under the electron microscope. the fine structure of t ...	1974	4825613
an intraerythrocytic parasite of the moroccan tortoise.		1974	4826117
carnitine synthesis in rat tissue slices.		1974	4826875
radiolabeled toxin for studying binding of cholera toxin and toxoids to intestinal mucosal receptor sites.		1974	4827729
glucose inhibition of the transport and phosphoenolpyruvate-dependent phosphorylation of galactose and fructose in vibrio cholerae.	vibrio cholerae followed a two-step pattern of growth in a medium containing glucose and either galactose or fructose. glucose was utilized first. glucose inhibited the uptake and phosphenolpyruvate-dependent phosphorylation of galactose and fructose.	1974	4828312
[bactericidal effect of vinegar on vibrio cholerae and some other intestinal pathogens. conclusion].		1974	4828910
proceedings: uterine venous prostaglandin f and oestrogen levels during ovine parturition: acute effects of cervical stimulation.		1974	4829181
the cardiovascular pharmacology of methyldopa using graphic segmental circulatory analysis.		1974	4829222
[synthesis and decomposition of l-asparagine in vibrios].		1974	4830044
[immunologic efficacy of cholerogen-anatoxin in tests on experimental animals].		1974	4830045
variations in hematologic responses to increased lead absorption in young children.	in the study of human populations, much emphasis is placed on the concentration of lead in whole peripheral blood. there is a considerable body of evidence which indicates that this measurement reflects recent and current assimilation of lead. while broad ranges in blood lead concentration have been associated with differing risks of toxicity for groups, it is not a precise index of adverse effect per se, even at elevated levels. within the red blood cell itself there is not a close association ...	1974	4831151
the serum factor stimulating colony formation in vitro by murine plasmacytoma cells: response to antigens and mineral oil.		1974	4832309
claim that two human linkage groups carry different loci for gpt and ldh withdrawn.		1974	4833247
taurine concentrations in congestive heart failure.	the concentration of taurine in the left ventricular muscle of hearts of patients who died of chronic congestive heart failure was twice that of patients who died of other causes and had no cardiac pathology. there was no corresponding difference in taurine concentrations in aortic tissue between the two groups. stress-induced hypertension in rats also led to an increase in taurine concentration in the heart, whereas that in skeletal muscle and brain showed no significant alteration when compare ...	1974	4833255
a field study of the correlation of static lime paper sampler with forage and cattle urine.		1974	4833331
neurosecretory cells in the frontal ganglion of the tobacco hornworm, manduca sexta.		1974	4833353
improved survival rates in dogs after extracorporeal circulation by improved control of heparin levels.		1974	4834066
improved survival rates in dogs after extracorporeal circulation by improved control of heparin levels.		1974	4834066
horizons in tumor immunology. a seminar.		1974	4834133
a new technique for in situ hepatic isolation and perfusion in the rabbit.		1974	4834211
inhibition of leukocyte migration by tumor-associated antigens in soluble extracts of human breast carcinoma.		1974	4835097
a contribution to biology of grawitz's kidney tumor: heterotransplanatation.		1974	4835486
[cholera in italy].		1974	4835943
potential anticancer agents. 10. synthesis of n-(4((2,4-diamino-7-pteridyl)methyl)-n10-methylamino)benzoyl)glutamic acid.		1974	4836410
effect of sodium chloride on growth of heterotrophic marine bacteria.		1974	4837198
human placental alkaline phosphatase, an inhibitor of hemagglutination by pr8-influenza a virus.		1974	4837607
[content of trypsin inhibitor in cow's colostrum].		1974	4838527
undialyzable growth factors for lactobacillus bifidus var. pennsylvanicus. protective effect of sialic acid bound to glycoproteins and oligosaccharides against bacterial degradation.		1974	4838871
[investigations concerning incidence of cholera--imported cases among returning tourists].		1974	4839940
[direct radioimmunoassay of serum thyroxine (author's transl)].		1974	4840175
experimental cancer immunotherapy using a neuraminidase-treated non-viable frozen tumor vaccine.		1974	4840798
the role of sialic acid in the determination of survival of rabbit erythrocytes in the circulation.		1974	4842011
isolation and biological properties of three classes of rabbit antibody to vibrio cholerae.		1974	4842331
tissue-binding properties of the cholera toxin.	[(125)i]choleragen was employed to study further the tissue-binding properties of highly purified choleragen. it was observed that [(125)i]choleragen was bound when combined with mucosal homogenates from all regions of the gastrointestinal tract of adult guinea pigs. gastric, duodenal, jejunal, and ileal mucosa appeared equally effective in toxin-binding capacity. preparations of large intestinal mucosa could bind an exceptionally larger amount of toxin. the binding property of small intestinal ...	1974	4842703
solubilized receptor for vitamin b12-intrinsic factor complex from human intestine.		1974	4845649
metastatic sarcoma. combined surgical and immunotherapeutic approach. neuraminidase treated tumor cells as tumor vaccine.		1974	4845897
the fatty acids present in the lipopolysaccharide of vibrio cholerae 569b (inaba).		1974	4847560
aberrant regulation of the agouti pigment pattern in the viable yellow mouse.		1974	4847754
[current status of cholera].		1974	4848414
on the specificity of neuraminidase. synthesis of benzyl 5-acetamido-3,5-dideoxy-beta-l-arabino-heptulosidaric acid, an a-ketosidic dicarboxylic derivative of n-acetyl-d-neuraminic acid resistant to vibrio cholerae neuraminidase.		1974	4853464
water transport across isolated term human amnion.		1974	4855409
changes in neutral lipid constituents during differentiation of the cellular slime mold, dictyostelium discoideum.		1974	4855616
proceedings: oestrogen biosynthesis in the ovine conceptus.		1974	4856461
growth of baby hamster kidney cells in media containing neuraminidase.		1974	4857158
discoidin, a developmentally regulated carbohydrate-binding protein from dictyostelium discoideum. purification and characterization.		1974	4858710
enhancement of hemagglutination inhibition titers in tissue-culture newcastle disease (tcnd) vaccinated chicken.		1974	4858747
granule release of enterochromaffin (ec) cells by cholera enterotoxin in the rabbit.		1974	4859341
membrane fusion and molecular segregation in phospholipid vesicles.		1974	4859411
membrane fusion and molecular segregation in phospholipid vesicles.		1974	4859411
neonatal hypoglycemia after beta-sympathomimetic tocolytic therapy.	the effect of oral beta-sympathomimetic tocolytic therapy on neonatal serum glucose concentrations in the first several hours after delivery was examined in 12 babies. hypoglycemia was noted in eight babies, and was sustained over at least a 30-minute period in five. the group with sustained hypoglycemia had a higher cord serum insulin concentration, a lower serum glucose nadir, and a more rapid initial rate of serum glucose disappearance than those babies with normoglycemia or transient hypogly ...	1974	423035
uterine malformation and fetal deformation.	beyond the enhanced miscarriage and prematurity associated with the structurally abnormal uterus, we have found 14 examples of fetal deformation secondary to uterine malformation with its consequent uterine constraint. in several instances the constellation of deformations had been misinterpreted as a multiple malformation disorder. one patient died of pulmonary hypoplasia, but all the survivors showed restoration toward normal form postnatally. recognition of the basic problem allows for surgic ...	1974	423019
the fine art of handling a hospitalized child.		1974	245737
span of apprehension in schizophrenic patients as a function of distractor masking and laterality.	twenty schizophrenic patients, 10 depressed control patients, and 20 normal control subjects were compared in a forced-choice, target-detection method for assessing the span of apprehension. the detection task required the subject to report which of 2 target letters was presented among 7 other (distractor) letters. performance accuracy was examined as a function of target location and whether the distractor letters were masked after their presentation. the backward masking of the distractors imp ...	1974	1537973
in vivo erythropoietin requirements of regenerating erythroid progenitors (bfu-e, cfu-e) in bone marrow of mice.	erythroid progenitors (b-8, b-4, cfu-e) in the femoral marrow of polycythemic mice were measured by in vitro culture assays after a single administration of bcnu or myleran. bcnu reduced pluripotent stem cells to 40% and erythroid progenitors to less than 5% of normal. b-8, the earliest erythroid progenitors, regenerated without erythropoietin (epo) completely within 5 days. at 14 days after bcnu, intermediate progenitors (b-4) attained 60% of their normal numbers and cfu-e attained approximatel ...	1974	444655
development of a local network for liver transplantation in the kinki region of japan: two-year experience of the recipient selection committee. recipient selection committee members of the kinki network for liver transplantation.		1974	1412975
fanconi's anaemia in adults: study of three families.		1974	414973
[ischemic heart disease].		1974	246815
hla antigen expression and malignant mesothelioma.	the expression of hla antigens by a tumor may determine its progression and metastatic potential by influencing the immune response to that tumor. the upregulation of hla antigen expression on some cell types by interferons (ifns) may contribute to their antitumor activity. malignant mesothelioma (mm) is a tumor that has a poor prognosis and is unaffected by conventional therapy, although immunotherapy has not been adequately assessed. in this study, we have examined the constitutive and ifn-ind ...	1974	1910807
government pressures on urological education.		1974	380108
several medical schools have begun to tackle sexual harassment issue.		1974	1423097
diffusion control in reversible enzyme reactions. applications to carbonic anhydrase.	the limit to the possible rate of reversible enzymatic reactions set by the diffusional motion has been considered. it is found that not only the diffusion of the reactants to the enzyme but also the diffusion away of the products can be rate limiting. to avoid assumptions about the detailed nature of the enzyme only diffusion in the bulk aqueous medium is treated. by such an approach one obtains an upper limit to the possible rate. in the latter half of the paper the derived general equations a ...	1974	414801
extra-abdominal manifestations of acute pancreatitis.		1974	380038
the choice of surgical procedure in congenital, infantile, and juvenile glaucoma.	trabeculotomy is successful in patients with an angle anomaly involving only the trabecular meshwork, but in those involving the trabecular meshwork with iris and/or cornea trabeculotomy combined with trabeculectomy is recommended. in cases of failed trabeculotomy or trabeculectomy, a molteno implant can be tried, although it does not work well in patients with congenital glaucoma. if all else fails, a cyclodestructive procedure is indicated and contact nd:yag laser cyclophotocoagulation is reco ...	1974	2366246
[the life and work of assistant professor václav skalák].		1974	380150
xylose test in malabsorption.		1974	423053
spinal chordomas.	a series of 54 patients with spinal chordomas were treated at memorial sloan-kettering cancer center between 1949 and 1976. thirty-six lesions were located in the sacrococcygeal region and 18 involved the vertebral column at a higher level. the male to female ratio was 35:19. vertebral chordomas generally occurred in a younger age group. our radiological findings suggest that there is marked soft-tissue extension anterior to the vertebral column at the time of initial diagnosis. eleven of 18 ver ...	1974	422982
[morphological evolution of the first lower premolar of some higher primates].	recent discoveries in africa, in asia and in europe of new fossils attributed to the ramapithecinae and/or to the australopithecinae seem to point out the monocuspid origin of man's first lower premolar the bicuspidy of the gigantopithecidae, the oreopithecidae' and the hominidae' first lower premolar, reached at different geological ages, give an example of parallel evolution.	1974	414845
polymyxin b-induced release of low-molecular-weight, heat-labile enterotoxin from escherichia coli.	polymyxin b-induced release of enterotoxin from escherichia coli strain h-10407 was demonstrated. incubation of e. coli cells derived from 6-h cultures with polymyxin caused the rapid release of enterotoxin with a molecular weight of approximately 20,000, as estimated by the gel filtration technique. the rapidity of the release of enterotoxin indicates that it probably resides in the periplasmic space of the cell. the low-molecular-weight enterotoxin possessed vascular permeability factor and di ...	1974	16558081
experimental cholera in chinchillas: the immune response in serum and intestinal secretions to vibrio cholerae and cholera toxin.	the immune response to vibrio cholerae and cholera toxin was studied in chinchillas inoculated intra-intestinally with 10(8) viable v. cholerae 596b. sera and intestinal fluids were collected from animals on days 1, 2, 3, 5, 7, 10, 14, 30, and 60 postinoculation, and antibodies were quantified by various methods. when radiovibriolytic and radiotoxin precipitin tests were used, a significant (fourfold) rise in both antibacterial and antitoxic titers was detected in intestinal fluids on the 2nd da ...	1974	16558096
growth inhibition of enteric bacteria by vibrio cholerae in nutrient media containing lactate, acetate, or citrate.	in cross-streak tests on nutrient agar containing lactate, acetate, or citrate, the growth of certain enteric bacteria was inhibited by themselves or by vibrio cholerae, or by both. this mimicked the activity of bacteriocins, but the phenomenon was attributable to the accumulation of carbonate and increased alkalinity of the media.	1974	15830491
analysis of the data in the literature on the sensitivity of cholera vibrios to tetracycline.	variation diagrams were proposed to be used for the analysis of the published data on the study of vibrio cholerae sensitivity to tetracycline. the diagrams provided systematization of dissimilar data of the experimental studies and a unique system of estimation was created. the analysis of the systematized data provided dividing of the vibrio cholerae strains tested into 4 groups differing in the levels of their sensitivity to tetracycline. the groups were independent of the vibrio cholerae bio ...	1975	5050
letter: halophilic non-cholera vibrio infections.		1975	46095
immunofluorescent studies on antibodies directed to a buried membrane structure present in lymphocytes and erythrocytes.	brief digestion of human peripheral blood lymphocytes by vibrio cholera neuraminidase (vcn) revealed hidden components of the membrane. autologous human serums contained antibodies directed to these components that were readily demonstrated by immunofluorescence. antibodies of similar specificity were found in all normal serums. the antibodies were principally of the igm variety with lesser amounts of the igg class present. they were equally active at 4 degrees c and 37 degrees c. the vcn reveal ...	1975	46880
neuraminidase sensitive antigenic determinants of plasma cell tumor membrane glycoproteins.		1975	47298
augmented uptake of neuraminidase-treated sheep red blood cells: participation of opsonic factors.	neuraminidase from vibrio cholerae (vcn) was used to treat sheep red blood cells (srbc) which were then incubated in vitro with murine peritoneal macrophages. the uptake of vcn-treated srbc by macrophages was greater than the uptake of srbc not treated with vcn. srbc opsonized with normal mouse serum (nms) were taken up to a greater extent than untreated srbc. srbc treated with vcn and opsonized with nms were phagocytosed to a greater extent than untreated srbc, vcn-treated srbc, or opsonized sr ...	1975	48553
[method of preparation of erythrocytic diagnostic agents for detection of antitoxic and antibacterial antibodies in el tor cholera].		1975	48596
the binding of cationized ferritin at the surfaces of ehrlich ascites tumor cells: the effect of ph and glutaraldehyde fixation.	the densities of cationized ferritin (cf) particles binding to the surfaces of cultured ehrlich ascites tumor cells were determined at ph 7.4, where the ferritin stain was applied either prior to or following glutaraldehyde fixation. the densities were also determined with cf adjusted to ph 1.9 and applied after fixation. for all fixed samples there was a higher density of particles bound to microvilli than to the spaces between them. treatment with neuraminidase removed more particles from mic ...	1975	49356
a comparison of "influenza c" with prototype myxoviruses: receptor-destroycing activity (neuraminidase) and structural polypeptides.		1975	49979
immunological study of anthranilate synthetase.	an immunological study of anthranilate synthetase (asase) has been initiated using quantitative precipitation, enzyme neutralization, and immunodiffusion methods. cross-reactivity of anthranilate synthetase-anthranilate-5-phosphoribosylpyrophosphate phosphoribosyltransferase (asase-prtase) from escherichia coli, klebsiella aerogenes, and salmonella typhimurium and asase from serratia marcescens and pseudomonas putida was detected with antibodies to ?e. coli trypsin-treated asase. cross-reactivit ...	1975	50316
[use of the immune tolerance induction in the production of an antilymphocyte serum (als) free of antibodies against serum proteins].	the possibility has been investigated of a direct gain of als free of undesirable antibodies against serum proteins by inducing immunologic tolerance in productive animals (pigs). preliminary experiments made with tolerogenic amounts of 10 and 50 ml of sera and with immunization by the serum alone proved applicability of this method. electrophoresis showed antibodies against 6 to 7 and 2 to 3 fractions in animals tolerated with 10 and 50 ml respectively, compared to 18 to 20 fractions in the con ...	1975	50969
vibriolytic igg immunocyte response of mice after primary and secondary immunization with cholera somatic antigens.	antibody plaque-forming cells (fc) to the somatic antigens of vibrio cholerae were enumerated in the spleen of mice after primary and secondary immunization with a heat-killed vaccine prepared from the vibrios. immunocytes releasing both high efficiency igm and low efficiency igg antibody were readily detected using a direct and facilitated plaque procedure in agar gel. whereas the peak numbers of igm-pfc after primary immunization occurred on days 12 to 14, the peak igg-pfc response developed s ...	1975	51000