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this might hurt a little. instead of going to court, healthcare workers should head to a flu-shot clinic. 200919972656
the severity of pandemic h1n1 influenza in the united states, from april to july 2009: a bayesian analysis.accurate measures of the severity of pandemic (h1n1) 2009 influenza (ph1n1) are needed to assess the likely impact of an anticipated resurgence in the autumn in the northern hemisphere. severity has been difficult to measure because jurisdictions with large numbers of deaths and other severe outcomes have had too many cases to assess the total number with confidence. also, detection of severe cases may be more likely, resulting in overestimation of the severity of an average case. we sought to e ...200919997612
[743 new york emergency room rotation under the threat of swine flu]. 200920027972
declining mortality in american crow (corvus brachyrhynchos) following natural west nile virus infection.the american crow (corvus brachyrhynchos) is known to suffer 100% mortality from infection with the new york 1999 strain of west nile virus (wnv). following the initial detection of wnv in north america in 1999, we measured prevalence of wnv-reactive antibodies ("seroprevalence") in free-ranging american and fish crows (corvus ossifragus) of central new jersey after each transmission season through 2005. in 2002, seroprevalence in american crow juveniles increased to 14% from the 5% of the previ ...200919848089
outbreak of 2009 pandemic influenza a (h1n1) at a new york city school.in april 2009, an outbreak of novel swine-origin influenza a (2009 h1n1 influenza) occurred at a high school in queens, new york. we describe the outbreak and characterize the clinical and epidemiologic aspects of this novel virus.200920042754
reconstructing influenza incidence by deconvolution of daily mortality time series.we propose a mathematically straightforward method to infer the incidence curve of an epidemic from a recorded daily death curve and time-to-death distribution; the method is based on the richardson-lucy deconvolution scheme from optics. we apply the method to reconstruct the incidence curves for the 1918 influenza epidemic in philadelphia and new york state. the incidence curves are then used to estimate epidemiological quantities, such as daily reproductive numbers and infectivity ratios. we f ...200920080801
prevalence of hemoglobin a1c greater than 6.5% and 7.0% among hospitalized patients without known diagnosis of diabetes at an urban inner city hospital.context: bronx, new york, an urban county with a large low-income, immigrant and minority population, has a prevalence of diabetes that is among the highest in the united states. objective: the aim of the study was to evaluate the utility of hemoglobin a1c (hba1c) in identifying patients at risk for diabetes on an in-patient medical service of a hospital serving a high prevalence community. design and setting: we conducted a prospective cohort study at an urban public hospital. patients: the stu ...201020080838
an analytical approach to clinical forensic evaluations of asylum seekers: the healthright international human rights clinic.healthright international, formerly doctors of the world-usa, has for the past 15years trained clinicians to perform forensic medical evaluations of torture survivors. as the burden of proof in asylum cases in the united states has increased, so has the scrutinizing of the evidence presented. we present a series of cases in which the scars themselves bear testimony to the applicant's case, bolstering the importance of photography in these cases.201020083050
burden of influenza-related hospitalizations among children with sickle cell disease.children with sickle cell disease (scd) are considered to be at high risk for complications from influenza infection despite minimal published data that characterize the burden of influenza in this population. our objectives were to (1) estimate the rate of influenza-related hospitalizations (irhs) among children with scd, (2) compare this rate with rates of children with cystic fibrosis (cf) and children with neither scd nor cf, and (3) explore mechanisms that underlie these potentially prevent ...201020100764
rapid influenza a testing for novel h1n1: point-of-care performance.the 2009 outbreak of novel influenza a h1n1 reached a pandemic status on june 11, 2009. early detection is a key factor for management and infection-control practices. recent studies have suggested a difference in performance of rapid influenza kits for influenza a h1n1. our goal was to evaluate the performance of the quickvue influenza a+b test (quidel corp., san diego, ca) in an emergency department setting and determine the most current epidemiologic trends in our community.201020107286
outbreaks of 2009 pandemic influenza a (h1n1) among long-term-care facility residents - three states, 2009.hospitalization and death from seasonal influenza are more common among older adults and in long-term--care facilities (ltcfs). early data from the 2009 pandemic influenza a (h1n1) outbreak indicated that attack rates among persons aged >or=65 years were lower than in other age groups, and anti-influenza a antibodies that cross-react with 2009 h1n1 could be detected in up to one third of healthy adults aged >60 years. based on these early data and anticipation of limited initial supplies of 2009 ...201020110935
possible underlying mechanisms for successful emergence of the mycobacterium tuberculosis beijing genotype strains.the wide geographic distribution of one clade of mycobacterium tuberculosis, the beijing genotype family, and its genetic homogeneity, suggests that strains belonging to this grouping might have a selective advantage over other m tuberculosis strains. this hypothesis was addressed by reviewing molecular-epidemiological, experimental, and clinical studies. beijing strains represent about 50% of strains in east asia and at least 13% of strains worldwide. their emergence might be linked to escape f ...201020113979
concentrations of selected organochlorines and chlorobenzenes in the serum of former love canal residents, niagara falls, new york.love canal, in niagara falls, ny is among the earliest and most significant hazardous waste sites in the usa, but no study has ever measured chemical body burdens in nearby residents to document that human exposure occurred. this study measured concentrations of selected organochlorines and chlorinated benzenes in archived serum samples collected from former love canal residents.201020117765
examining the temporal relationship between criminal justice involvement and sexual risk behaviors among drug-involved men.although criminal justice involvement has repeatedly been associated with human immunodeficiency virus (hiv)/sexually transmitted infection prevalence and sexual risk behaviors, few studies have examined whether arrest or incarceration uniquely contributes to sexually risky behavior. we examined the temporal relationship between criminal justice involvement and subsequent sexual hiv risk among men in methadone maintenance treatment in new york city. a random sample of 356 men was interviewed at ...201020143270
african ancestry allelic variation at the myh9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in hispanic americans.recent studies identified myh9 as a major susceptibility gene for common forms of non-diabetic end-stage kidney disease (eskd). a set of african ancestry dna sequence variants comprising the e-1 haplotype, was significantly associated with eskd. in order to determine whether african ancestry variants are also associated with disease susceptibility in admixed populations with differing genomic backgrounds, we genotyped a total of 1425 african and hispanic american subjects comprising dialysis pat ...201020144966
public hospital-based laboratory experience during an outbreak of pandemic influenza a (h1n1) virus infections.the experience of a public hospital virology laboratory during a springtime 2009 outbreak of a novel influenza a (h1n1) virus in new york state is described. influenza virus was isolated from 145 of 613 respiratory swab specimens. symptoms of fever (temperature, 102.7 +/- 0.32 degrees f), cough, upper respiratory infection, myalgia, and headache were reported. atypical symptoms of nausea/vomiting and diarrhea were also observed. illness occurred mainly in patients <or=21 years of age (85/145 pat ...201020147645
interest and beliefs about brca genetic counseling among at-risk latinas in new york city.latinas are less likely to use genetic services (counseling and testing) for hereditary breast and/or ovarian cancer risk compared to other ethnic groups. meanwhile, little is known about barriers to genetic counseling among latinas at increased risk of inherited breast cancer.201020151317
nosocomial swine influenza (h1n1) pneumonia: lessons learned from an illustrative case.in the spring of 2009, our institution found itself at the epicentre of the "herald wave" of the swine influenza (h1n1) pandemic in new york. we were inundated with hundreds of patients exhibiting influenza-like illnesses (ilis), presenting for rapid influenza a testing. during this pandemic, an infant with newly diagnosed acute lymphatic leukaemia (all) was admitted for induction chemotherapy. after being in hospital for a week, she developed high fever and shortness of breath, although her che ...201020153551
association between residential proximity to perc dry cleaning establishments and kidney cancer in new york city.perchloroethylene (perc) is commonly used as a dry cleaning solvent and is believed to be a human carcinogen, with occupational exposure resulting in elevated rates of kidney cancer. living near a dry cleaning facility using perc has been demonstrated to increase the risk of perc exposure throughout the building where the dry cleaning is conducted, and in nearby buildings. we designed this study to test the hypothesis that living in an area where there are many perc dry cleaners increases perc e ...201020169137
joint modeling of intercourse behavior and human fecundability using structural equation models.human fecundability is defined as the probability of conception during a menstrual cycle among couples at risk for pregnancy. it is highly relevant for understanding human reproduction and represents a series of highly interrelated and timed processes. the statistical literature has recognized the need to incorporate both biological and behavioral factors (barrett and marshall, 1969; dunson and stanford, 2005) when modeling conception probabilities, given that intercourse during the fertile wind ...201020173100
pulsed-field gel electrophoresis diversity of human and bovine clinical salmonella isolates.pulsed-field gel electrophoresis (pfge) characterization of 335 temporally and spatially matched clinical, bovine, and human salmonella enterica subsp. enterica isolates revealed 167 xbai pfge patterns. these isolates were previously classified into 51 serotypes and 73 sequence types, as determined by multilocus sequence typing. discriminatory power of pfge (simpson's index, d = 0.991) was considerably higher than that of multilocus sequence typing (d = 0.920) or serotyping (d = 0.913). although ...201020180633
dry weather induces outbreaks of human west nile virus infections.since its first occurrence in the new york city area during 1999, west nile virus (wnv) has spread rapidly across north america and has become a major public health concern in north america. by 2002, wnv was reported in 40 states and the district of columbia with 4,156 human and 14,539 equine cases of infection. mississippi had the highest human incidence rate of wnv during the 2002 epidemic in the united states. epidemics of wnv can impose enormous impacts on local economies. therefore, it is a ...201020181272
pancreatic acinar cell carcinomas with prominent ductal differentiation: mixed acinar ductal carcinoma and mixed acinar endocrine ductal carcinoma.pancreatic acinar cell carcinomas (accs) are clinically and pathologically distinct from pancreatic ductal adenocarcinomas (pdas). whereas endocrine differentiation has been well shown in accs, significant ductal components are rare. this paper reviews the clinicopathologic features of a series of accs with prominent ductal differentiation.201020182344
household transmission of 2009 influenza a (h1n1) virus after a school-based outbreak in new york city, april-may 2009.in april 2009, an outbreak due to infection with the 2009 pandemic influenza a (h1n1) virus (ph1n1) was investigated in a new york city high school. we surveyed household contacts of ill students to characterize the extent of transmission within households, identify contact groups at highest risk for illness, and assess the potential for preventing household transmission. influenza-like illness (ili) was reported by 79 of 702 household contacts (11.3% attack rate). multivariate analysis showed t ...201020187740
lessons from queens. 201020187742
salmonella enterica serotype cerro among dairy cattle in new york: an emerging pathogen?the focus of this study was salmonella enterica serotype cerro, a potentially emerging pathogen of cattle. our objectives were to document the within-herd prevalence of salmonella cerro among a sample of new york dairy herds, to describe the antimicrobial resistance patterns and pulsed-field gel electrophoresis types of the isolates, and to elucidate the status of this serotype as a bovine pathogen. data were collected prospectively from dairy herds throughout new york that had at least 150 lact ...201020187753
double jeopardy: the impact of neoliberalism on care workers in the united states and south africa.many researchers have explored how neoliberal restructuring of the workplace has reduced the standard of living and increased workplace stress among private sector employees. however, few have focused on how neoliberal restructuring of public policy has had similar effects on the public sector workforce. using original case study research, the authors examine how two iconic pieces of neoliberal policy--the 1996 welfare reform bill in the united states and the gear macroeconomic policy in south a ...201020198806
terrestrial rabies and human postexposure prophylaxis, new york, usa.during 1993-2002, cats accounted for 2.7% of rabid terrestrial animals in new york but for one third of human exposure incidents and treatments. nonbite exposures and animals of undetermined rabies status accounted for 54% and 56%, respectively, of persons receiving rabies treatments.201020202438
thomas g. pickering - a great mentor.professor thomas g. pickering passed away on 14 may 2009. i studied at the hypertension center, the new york presbyterian hospital/cornell university medical college, ny, usa from 1 september 1998 to 30 november 2000. professor pickering was a great mentor who showed how important the following issues were: (i) how important it is to stick to 'clinical viewpoint' and generate clinical ideas through 'words'. he introduced the beautiful medical words 'white-coat hypertension' and 'masked hypertens ...201020216062
absence of genomic brca1 and brca2 rearrangements in ashkenazi breast and ovarian cancer families.a substantial proportion of ashkenazi jewish (aj) breast and ovarian cancer families carry one of three founder mutations in brca1 (185delag, 5382insc) and brca2 (6174delt). non-founder mutations are identified in another 2-4% of such families. the extent to which major genomic rearrangements in brca contribute to breast and ovarian cancer in the ashkenazim is not well understood. we identified aj individuals with breast and/or ovarian cancer undergoing hereditary breast/ovarian cancer risk asse ...201020221693
unseasonal transmission of h3n2 influenza a virus during the swine-origin h1n1 pandemic.the initial wave of swine-origin influenza a virus (pandemic h1n1/09) in the united states during the spring and summer of 2009 also resulted in an increased vigilance and sampling of seasonal influenza viruses (h1n1 and h3n2), even though they are normally characterized by very low incidence outside of the winter months. to explore the nature of virus evolution during this influenza "off-season," we conducted a phylogenetic analysis of h1n1 and h3n2 sequences sampled during april to june 2009 i ...201020237080
impact of non-pharmaceutical interventions on uris and influenza in crowded, urban households.we compared the impact of three household interventions-education, education with alcohol-based hand sanitizer, and education with hand sanitizer and face masks-on incidence and secondary transmission of upper respiratory infections (uris) and influenza, knowledge of transmission of uris, and vaccination rates.201020297744
severity of 2009 pandemic influenza a (h1n1) virus infection in pregnant women.to examine 2009 h1n1 influenza illness severity and the effect of antiviral treatment on the severity of illness among pregnant women.201020308830
2009 pandemic influenza a (h1n1) in pregnant women requiring intensive care - new york city, 2009.pregnant women are at increased risk for severe illness and complications from infection with seasonal influenza and 2009 pandemic influenza a (h1n1). to characterize the severity of 2009 h1n1 infection in pregnant women, the new york city department of health and mental hygiene (dohmh) conducted active and passive surveillance for cases of 2009 h1n1 infection in pregnant women requiring intensive care. this report summarizes the results of that surveillance, which found that, during 2009, 16 pr ...201020339343
assessing criminal justice involvement as an indicator of human immunodeficiency virus risk among women in methadone treatment.this study examines the relationship between criminal justice involvement and high-risk sexual partnerships among a random sample of 416 women in methadone treatment in new york city. logistic regression models were used to estimate the associations between recent criminal justice involvement (arrest or incarceration in the past 6 months) and recent high-risk partnerships (multiple sex partners, sex trading, or sex with a risky partner in the past 6 months) when adjusting for sociodemographic fa ...201020356702
unexplained increased incidence of legionnaires disease during the "herald wave" of the h1n1 influenza pandemic. 201020367323
which health care workers were most affected during the spring 2009 h1n1 pandemic?to identify health care workers most at risk for h1n1 infection before vaccination and compare health outcomes after vaccination.201020389195
pandemic influenza: antiviral preparedness and health care workers.the primary objective of this study was to determine the preparedness for pandemic influenza of hospitals, in terms of amount of antiviral drugs on hand and employee vaccination rates, in the finger lakes region (flr) of western new york.201020389196
albany prize honors genome decoders. 201020407050
deaths from seasonal influenza among pregnant women in the united states, 1998-2005.to estimate pregnancy-related mortality caused by seasonal influenza in the united states for comparison with the current 2009 influenza a h1n1 pandemic.201020410763
changing sociodemographic and clinical characteristics of tuberculosis among hiv-infected patients, new york city, 1992-2005.although highly active antiretroviral therapy (haart) has decreased human immunodeficiency virus (hiv)-related morbidity, tuberculosis remains an important disease among hiv-infected individuals.201020415570
fatalities associated with the 2009 h1n1 influenza a virus in new york city.background. when the 2009 h1n1 influenza a virus emerged in the united states, epidemiologic and clinical information about severe and fatal cases was limited. we report the first 47 fatal cases of 2009 h1n1 influenza in new york city. methods. the new york city department of health and mental hygiene conducted enhanced surveillance for hospitalizations and deaths associated with 2009 h1n1 influenza a virus. we collected basic demographic and clinical information for all patients who died and co ...201020420514
attitudes and perceptions of the hpv vaccine in caribbean and african-american adolescent girls and their parents.to describe attitudes and perceptions toward acceptability of human papilloma virus (hpv) vaccination among inner city caribbean (ca) and african american (aa) adolescents and their parents, and discuss correlates that may be associated with these factors.201020452260
mental distress and service utilization among help-seeking, community-dwelling older adults.this study aimed to characterize healthcare and human services utilization among mentally distressed and non-distressed clients receiving in-home care management assessment by aging services provider network (aspn) agencies in the u.s.a.201020478101
a comparison of statistical techniques for combining modeled and observed concentrations to create high-resolution ozone air quality surfaces.air quality surfaces representing pollutant concentrations across space and time are needed for many applications, including tracking trends and relating air quality to human and ecosystem health. the spatial and temporal characteristics of these surfaces may reveal new information about the associations between emissions, pollution levels, and human exposure and health outcomes that may not have been discernable before. this paper presents four techniques, ranging from simple to complex, to sta ...201020480858
identification of environmental covariates of west nile virus vector mosquito population abundance.the rapid spread of west nile virus (wnv) in north america is a major public health concern. culex pipiens-restuans is the principle mosquito vector of wnv in the northeastern united states while aedes vexans is an important bridge vector of the virus in this region. vector mosquito abundance is directly dependent on physical environmental factors that provide mosquito habitats. the objective of this research is to determine landscape elements that explain the population abundance and distributi ...201020482343
urinary neutrophil gelatinase-associated lipocalin is a promising biomarker for late onset culture-positive sepsis in very low birth weight infants.need for the early identification of sepsis in very low birth weight (vlbw) infants has led to the search for reliable biomarkers. this study aims to determine whether urinary neutrophil gelatinase-associated lipocalin (ungal) rises in culture-positive sepsis and, if so, is elevated at the time sepsis is suspected. this is a prospective study of 91 vlbw infants whose urine was collected daily for ungal analysis. in 65 episodes of suspected sepsis, four groups were identified: a) culture-positive ...201020496473
acquiring human immunodeficiency virus during pregnancy and mother-to-child transmission in new york: 2002-2006.to assess perinatal human immunodeficiency virus (hiv) exposure and factors associated with mother-to-child hiv transmission.201020502297
novel influenza a(h1n1) in a pediatric health care facility in new york city during the first wave of the 2009 pandemic.to describe the burden of care experienced by our pediatric health care facility in new york, new york, from may 3, 2009, to july 31, 2009, during the novel influenza a(h1n1) pandemic that began in spring 2009.201020048238
sarcoidosis in world trade center rescue workers presenting with rheumatologic manifestations.the health consequences of the world trade center collapse are unknown, but likely to be significant and may take years to fully appreciate. sarcoidosis is a multisystem inflammatory disorder of unknown etiology characterized pathologically by noncaseating granulomas. inciting events, such as infectious agents or possible environmental exposures, have been postulated as the source of antigen exposure initiating an inflammatory cascade. we describe 2 cases of sarcoidosis in rescue workers with si ...201020051752
patients hospitalized with 2009 pandemic influenza a (h1n1) - new york city, may 2009.the first cases of 2009 pandemic influenza a (h1n1) in new york city occurred in april 2009, raising many questions about how best to contain the epidemic. to rapidly assess the severity of influenza illness and identify persons at highest risk for severe infection, the new york city (nyc) department of health and mental hygiene (dohmh) reviewed the medical charts of the first 99 patients with laboratory confirmed h1n1 admitted to any nyc hospital. the purpose of the review was to characterize t ...201020057350
detecting acute human immunodeficiency virus infection using 3 different screening immunoassays and nucleic acid amplification testing for human immunodeficiency virus rna, 2006-2008.the yield of nucleic acid amplification testing (naat) after routine screening for human immunodeficiency virus (hiv) antibody to detect acute hiv infection (ahi) may vary with different hiv-antibody assays.201020065201
validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and cbmn assays in a mouse model.automation of radiation biodosimetry is one of the top priority tasks considered by the office of science and technology policy and the homeland security council in preparation for the nation's readiness for a possible radionuclear terrorist attack. the center for biophysical assessment and risk management following irradiation, a consortium of researchers and institutions centered at the university of rochester, has been investigating automated scoring of radiation-induced micronucleus formatio ...201020065686
association of a functional polymorphism in the cholesteryl ester transfer protein (cetp) gene with memory decline and incidence of dementia.polymorphisms in the cholesteryl ester transfer protein (cetp) gene have been associated with exceptional longevity and lower cardiovascular risk, but associations with memory decline and dementia risk are unclear.201020068209
from bench to clinic: accessing promising investigational medications for patients with hiv infection in an urban family health center.patients who experience failure of treatment for human immunodeficiency virus and who have no other treatment options can sometimes obtain promising investigational medications through expanded access programs. however, psychosocial and socioeconomic factors, common among underserved populations, create barriers to enrollment at referral centers. to increase access for unstable patients, an urban family health center developed the capacity to provide investigational medications directly to patie ...201020823350
web-based self-triage of influenza-like illness during the 2009 h1n1 influenza pandemic.the sudden emergence of 2009 h1n1 influenza in the spring of that year sparked a surge in visits to emergency departments in new york city and other communities. a larger, second wave of cases was anticipated the following autumn. to reduce a potential surge of health system utilization without denying needed care, we enlisted the input of experts from medicine, public health, nursing, information technology, and other disciplines to design, test, and deploy clinical algorithms to help minimally ...201020605260
functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility.the genetic mechanisms underlying asthma remain unclear. increased permeability of the microvasculature is a feature of asthma, and the sphingosine-1-phosphate receptor (s1pr1) is an essential participant regulating lung vascular integrity and responses to lung inflammation.201020624651
national institute of mental health multisite eban hiv/std prevention intervention for african american hiv serodiscordant couples: a cluster randomized trial.human immunodeficiency virus (hiv) has disproportionately affected african americans. couple-level interventions may be a promising intervention strategy.201020625011
impact of timing of birth and resident duty-hour restrictions on outcomes for small preterm infants.the goal was to examine the impact of birth at night, on the weekend, and during july or august (the first months of the academic year) and the impact of resident duty-hour restrictions on mortality and morbidity rates for very low birth weight infants.201020643715
toward a methodology for substate projections of registered nurse supply and demand in new york.even as concerns about nursing shortages continue nationwide and for individual states in the united states, there is little information on the impact of nursing shortages at substate levels, such as counties or groups of small counties. national and state level assessments can mask wide geographic variation in the distribution of registered nurses (rns). the center for health workforce studies at the school of public health, university at albany, developed a practical approach to projecting rn ...201020653217
complete nucleotide sequence of the incn plasmid pkox105 encoding vim-1, qnrs1 and shv-12 proteins in enterobacteriaceae from bolzano, italy compared with incn plasmids encoding kpc enzymes in the usa.we determined the complete nucleotide sequence of pkox105, a 54 641 bp plasmid from a klebsiella oxytoca strain that was isolated from a resident of a long-term-care facility in bolzano, italy.201020656680
case fatality rates based on population estimates of influenza-like illness due to novel h1n1 influenza: new york city, may-june 2009.the public health response to pandemic influenza is contingent on the pandemic strain's severity. in late april 2009, a potentially pandemic novel h1n1 influenza strain (nh1n1) was recognized. new york city (nyc) experienced an intensive initial outbreak that peaked in late may, providing the need and opportunity to rapidly quantify the severity of nh1n1.201020657738
conversations with harvey. interview by lori ashcraft and william a anthony. 201020666195
extracellular mass/body cell mass ratio is an independent predictor of survival in peritoneal dialysis patients.malnutrition is a strong predictor of mortality in peritoneal dialysis (pd) patients. extracellular mass (ecm) contains all the metabolically inactive, whereas body cell mass (bcm) contains all the metabolically active, tissues of the body. ecm/bcm ratio is a highly sensitive index of malnutrition. the objective of this study was to explore the relationship between ecm/bcm ratio and survival in pd patients. we enrolled 62 patients from november 2000 to july 2008. on enrollment, demographic, clin ...201020671743
pandemic (h1n1) 2009 surveillance for severe illness and response, new york, new york, usa, april-july 2009.on april 23, 2009, the new york city department of health and mental hygiene (dohmh) was notified of a school outbreak of respiratory illness; 2 days later the infection was identified as pandemic (h1n1) 2009. this was the first major outbreak of the illness in the united states. to guide decisions on the public health response, the dohmh used active hospital-based surveillance and then enhanced passive reporting to collect data on demographics, risk conditions, and clinical severity. this surve ...201020678320
laboratory surge response to pandemic (h1n1) 2009 outbreak, new york city metropolitan area, usa.the north shore-long island jewish health system laboratories serve 15 hospitals and affiliated regional physician practices in the new york city metropolitan area, with virus testing performed at a central reference laboratory. the influenza a pandemic (h1n1) 2009 outbreak began in this area on april 24, 2009, and within weeks respiratory virus testing increased 7.5 times. in response, laboratory and client service workforces were increased, physical plant build-out was completed, testing parad ...201020031036
point counterpoint: mandatory flu vaccination for health care workers. 201020032660
point counterpoint: mandatory flu vaccination for health care workers. 201020032661
point counterpoint: mandatory flu vaccination for health care workers. 201020032662
h1n1 influenza: contact investigation burden because of failure to institute influenza precautions in patients with negative rapid influenza diagnostic test results. 201019968491
ground zero recollections of us public health service nurses deployed to new york city in september 2001.the events of september 11, 2001, set in motion the broadest emergency response ever conducted by the us department of health and human services. in this article, some of the nurses who deployed to new york city in the aftermath of that horrific attack on the united states offer their recollections of the events. although public health service commissioned corps (phs cc) officers participated in deployments before 9/11, this particular deployment accelerated the transformation of the phs cc, bec ...201020510700
utilization of an incident command system for a public health threat: west nile virus in nassau county, new york, 2008.the summer of 2008 in nassau county, new york, was marked by a historic season of human west nile virus illness and west nile virus activity in mosquitoes. the commissioner of health of the state of new york declared a public health threat, and a decision was made to use adulticide for mosquito control. in contrast to prior years, the nassau county department of health utilized the incident command system (ics) to coordinate a multidisciplinary and multidepartment response to this public health ...201020520369
mutational analysis of hoxa2 and six2 in a bronx population with isolated microtia.microtia is a developmental malformation of the external ear with genetic and environmental causes. the prevalence of microtia varies but several studies suggest increased incidence in hispanic and african american populations. no causal genetic mutations have been identified in these populations. mutations in the homeobox gene hoxa2 caused microtia in a single iranian family. another homeobox gene, six2, acts downstream of hoxa2 during development and provides another possible candidate for mut ...201020542577
the 1918 influenza epidemic in new york city: a review of the public health response.new york city approached the 1918 influenza epidemic by making use of its existing robust public health infrastructure. health officials worked to prevent the spread of contagion by distancing healthy new yorkers from those infected, increasing disease surveillance capacities, and mounting a large-scale health education campaign while regulating public spaces such as schools and theaters. control measures, such as those used for spitting, were implemented through a spectrum of mandatory and volu ...201020568569
"better off in school": school medical inspection as a public health strategy during the 1918-1919 influenza pandemic in the united states.during the 1918-1919 influenza pandemic in the united states, most cities responded by implementing community mitigation strategies, such as school closure. however, three cities--new york city, chicago, and new haven, connecticut--diverged from the dominant pattern by keeping their public schools open while the pandemic raged. this article situates the experiences of these three cities in the broader context of the progressive era, when officials and experts put great faith in expanding public ...201020568692
expanded hiv testing and trends in diagnoses of hiv infection - district of columbia, 2004-2008.in the district of columbia (dc), the human immunodeficiency virus (hiv) case rate is nearly 10 times the u.s. rate and higher than comparable u.s. cities, such as baltimore, philadelphia, new york city, detroit, and chicago. in june 2006, the dc department of health (dcdoh) began implementing cdc's 2006 recommendations for routine, voluntary hiv screening in health-care settings. to describe recent trends in hiv disease and testing, cdc and dcdoh analyzed dc hiv case surveillance data, hiv test ...201020577154
h1n1 swine flu: the 2010 perspective--a new york academy of sciences meeting.the h1n1 swine flu: the 2010 perspective conference, held in new york city, included topics covering new research developments regarding the h1n1 influenza virus. this conference report highlights selected presentations on high-yield reassortant viral production, virus transmission and pathogenesis in ferret and guinea pig models, and the advantages of virus-like particle vaccines. fatal pathology findings from the 2009 h1n1 strain in new york, and preparedness for and response to the 2009 pande ...201020582868
short communication: no evidence of htlv-3 and htlv-4 infection in new york state subjects at risk for retroviral infection.the primate t-cell lymphoma viruses (ptlv) are divided into six distinct species. the biology and epidemiology of ptlv-1 and ptlv-2 are very well understood. however, that of ptlv-3, 4, 5, and 6 are not. recently, in cameroon, three and one humans were shown to be infected with htlv-3 and htlv-4, respectively. we undertook a study to ascertain whether any of these two retroviruses were present in the peripheral blood mononuclear cell dna of new york state subjects deemed at risk for ptlv infecti ...201020929392
the prevalence of cryptosporidium, and identification of the cryptosporidium horse genotype in foals in new york state.to date, little is known about the prevalence, genotypes and zoonotic potential of cryptosporidium spp. affecting horses, especially in north america. a cross-sectional study was conducted in new york, usa between february 25th and may 1st 2009. fecal samples were collected from three hundred and forty nine 1-10-week-old foals and their dams on 14 different broodmare farms. all fecal samples were screened for cryptosporidium spp. using a direct immunofluorescence assay (dfa). dna extraction and ...201020932647
reflex testing of resected stage i through iii lung adenocarcinomas for egfr and kras mutation: report on initial experience and clinical utility at a single center.the genes kras and egfr have emerged as potential targets for therapy in lung adenocarcinoma; mutations in these genes can be found in almost half of patients. in anticipation of the clinical importance of molecularly defined adenocarcinoma subgroups for the treatment of patients with resected stages i through iii lung adenocarcinoma, the memorial sloan-kettering cancer center (mskcc) departments of surgery and pathology have collaborated since 2006 to conduct reflex testing of tumor specimens f ...201020933246
breast cancer in women with human immunodeficiency virus infection: pathological, clinical, and prognostic implications.aids and breast cancer have become two important public health issues for women. of interest is the prolonged survival of patients diagnosed with hiv infection as a result of the use of highly active antiretroviral therapy (haart). with improved survival, we are likely to see more hiv-infected patients with breast cancer.201020950138
hiv and hcv health beliefs in an inner-city community.summary.  chronic infection with the hepatitis c virus (hcv) is more prevalent than human immunodeficiency virus (hiv) infection, but more public health resources are allocated to hiv than to hcv. given shared risk factors and epidemiology, we compared accuracy of health beliefs about hiv and hcv in an at-risk community. between 2002 and 2003, we surveyed a random patient sample at a primary care clinic in new york. the survey was organized as domains of common sense model of self-regulation: ca ...201020950406
biodiversity on broadway--enigmatic diversity of the societies of ants (formicidae) on the streets of new york city.each year, a larger proportion of the earth's surface is urbanized, and a larger proportion of the people on earth lives in those urban areas. the everyday nature, however, that humans encounter in cities remains poorly understood. here, we consider perhaps the most urban green habitat, street medians. we sampled ants from forty-four medians along three boulevards in new york city and examined how median properties affect the abundance and species richness of native and introduced ants found on ...201020957156
genomewide linkage and peakwide association analyses of carotid plaque in caribbean hispanics.atherosclerosis is a complex subclinical cardiovascular disorder with a substantial genetic component. this study sought to identify genetic loci influencing carotid plaque in 2 independent samples.201020966410
non-specific laboratory test indicators of severity in hospitalized adults with swine influenza (h1n1) pneumonia. 201020967480
reducing drug use, human immunodeficiency virus risk, and recidivism among young men leaving jail: evaluation of the real men re-entry program.this study assesses the impact of real men (returning educated african-american and latino men to enriched neighborhoods), an intervention designed to reduce drug use, risky sexual behavior and criminal activity among 16-18-year-old males leaving new york city jails.201020970079
herpes simplex virus type 2 associated with hiv infection among new york heterosexuals living in high-risk areas.herpes simplex virus type 2 (hsv-2) has been shown to increase the risk of sexual human immunodeficiency virus (hiv) transmission. a matched case-control design was used to examine the association between hsv-2 and hiv infection among heterosexuals in 'high-risk areas' (hras) in new york city (nyc). we identified nyc hras using hiv surveillance data on heterosexual-related adult hiv diagnoses and usa census data on household poverty. heterosexuals who were socially or geographically linked to an ...201020975092
circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults.the specificity and duration of circulating human antibody-secreting cells (ascs) after vaccination have been well described, but characteristics of ascs during acute respiratory infections have not been well studied.201020979459
does pediatrics need its own bioethics?pediatric bioethics raises unique issues because children are constantly growing, developing, and changing. the ethical issues that arise for newborns are different from those that arise for seven-year-olds or 17-year-olds. furthermore, children do not develop cognitive capacities or moral reasoning skills at the same rate. thus, it is difficult to generalize about what is appropriate or inappropriate for children in either the clinical or the research setting. this article responds to some of t ...201021037414
hiv type 2 in new york city, 2000-2008.antibody cross-reactivity complicates differential diagnosis of human immunodeficiency virus (hiv) type 2 (hiv-2) using standard serologic screening and confirmatory tests for hiv. hiv type 1 (hiv-1) viral load testing does not detect hiv-2. although hiv-2 is, in general, less pathogenic than hiv-1, it can lead to immunosuppression and clinical aids, and there are important differences in the selection of antiretroviral therapy for hiv-2-related immunosuppression that make it imperative to diffe ...201021039219
knowledge, attitudes, and practices of us travelers to asia regarding seasonal influenza and h5n1 avian influenza prevention measures.international travel is a potential risk factor for the spread of influenza. in the united states, approximately 5%-20% of the population develops an influenza-like illness annually. the purpose of this study was to describe the knowledge, attitude, and practices of us travelers to asia regarding seasonal influenza and h5n1 avian influenza (ai) prevention measures.201021050316
a rapid, safe, and low-cost technique for the induction of mild therapeutic hypothermia in post-cardiac arrest patients.the benefits of inducing mild therapeutic hypothermia (mth) in cardiac arrest patients are well established. timing and speed of induction have been related to improved outcomes in several animal trials and one human study. we report the results of an easily implemented, rapid, safe, and low-cost protocol for the induction of mth.201021050652
somos: evaluation of an hiv prevention intervention for latino gay men.latino gay men face multiple barriers to human immunodeficiency virus (hiv) prevention, in particular a lack of intervention programs that integrate prevention messages with cultural norms and address issues of social marginalization from multiple communities (gay community and latino community), homophobia and racism. in order to address these specific issues, a multilayered hiv intervention was designed to incorporate and integrate psychosocial and community factors through multiple session gr ...201021059799
phylogeography of the spring and fall waves of the h1n1/09 pandemic influenza virus in the united states.spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in humans has been documented throughout the 20th century but never understood at a molecular level. however, the unprecedented intensity of sampling and whole-genome sequencing of the h1n1/09 pandemic virus now makes such an approach possible. to determine whether the spring and fall waves of the h1n1/09 influenza pandemic were associated with different epidemiological patterns, we undertook a larg ...201021068250
novel sqstm1 mutations in patients with paget's disease of bone in an unrelated multiethnic american population.more than 20 mutations of the sequestosome 1 (sqstm1) gene have been reported in patients of european descent affected by paget's disease of bone (pdb). in this investigation, a systematic screening for sqstm1 mutations was conducted in consecutively evaluated unrelated patients with phenotypical pdb living in the new york city area (ny, united states). seventy unrelated pdb patients with a multiethnic background, mostly of jewish, italian american, and western european ancestries, were recruite ...201021073987
gender and age patterns in hsv-2 and hiv infection among non-injecting drug users in new york city.to examine prevalence of and associations between herpes simplex virus type 2 (hsv-2) infection and hiv infection among never-injecting heroin and cocaine drug users (nidus) in new york city.201020838366
oxidant generation capacity of source-apportioned pm2.5.while many studies found associations between ambient particulate matter (pm) and morbidity or mortality outcomes, it is unclear whether these associations were dependent on the composition of pm, which varies with the source of that pm. we address this knowledge gap by conducting a time-series pm-health effects assessment that specifically investigates the role of source-apportioned fine pm (pm2.5) on the oxidant generation capacity that might be responsible for respiratory and cardiovascular h ...201020843277
signs of the 2009 influenza pandemic in the new york-presbyterian hospital electronic health records.in june of 2009, the world health organization declared the first influenza pandemic of the 21(st) century, and by july, new york city's new york-presbyterian hospital (nyph) experienced a heavy burden of cases, attributable to a novel strain of the virus (h1n1pdm).201020844592
post-traumatic stress disorder and hiv: a snapshot of co-occurrence.although the medical advances in the area of human immunodeficiency virus (hiv)/acquired immune deficiency syndrome (aids) have undoubtedly improved the length and quality of life for those who are hiv-affected and medication adherent, there are still many psychosocial obstacles to effective hiv/aids medication adherence. recent research has focused on one such obstacle. the significant link between post-traumatic stress disorder (ptsd) and hiv. this article reports on the nature of this relatio ...201020853209
2009 h1n1 swine flu: the 2010 perspective.in may 2009, as the h1n1 swine flu outbreak was in the early stages, a conference was held at the new york academy of sciences to discuss what was known about the virus and what was being done to stop the outbreak. in may 2010, a follow-up conference was again held at the new york academy of sciences, but now to discuss the h1n1 outbreak retrospectively. the report presented here summarizes the 2010 conference proceedings.201020860673
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