Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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chlamydophila psittaci in fulmars, the faroe islands. | chlamydophila psittaci was detected in 10% of 431 fulmars examined from the faroe islands. analysis of ompa showed a sequence almost identical to that of the type strain. the origin of c. psittaci outbreaks in fulmars is discussed. despite a high level of exposure, the risk for transmission of c. psittaci to humans is low. | 2006 | 16494766 |
'blind' antibiotic treatment targeting chlamydia is not effective in patients with malt lymphoma of the ocular adnexa. | recent results have implicated chlamydia, especially chlamydia psittaci, in the development of ocular adnexal lymphoma in the large majority of patients. we present our experience with ex-juvantibus antibiotic treatment in patients diagnosed with malt lymphoma of the ocular adnexa. | 2006 | 16500916 |
infectious agents in mucosa-associated lymphoid tissue-type lymphomas: pathogenic role and therapeutic perspectives. | mucosa-associated lymphoid tissue (malt) lymphoma probably constitutes the best in vivo model showing how complex interplay between b lymphocytes and the surrounding microenvironment may lead to a neoplastic disorder. after the seminal discovery of the pathogenic association between helicobacter pylori and gastric malt lymphomas, evidence suggests the possible involvement of other infectious agents in the development of malt lymphomas arising at different body sites. although several other bacte ... | 2006 | 16507206 |
marginal zone lymphoma. | marginal zone lymphomas (mzls) comprise 3 distinct entities: extranodal mzl of mucosa-associated lymphoid tissue (malt), splenic mzl, and nodal mzl. gastric malt lymphoma is the most common extranodal mzl and often develops as a result of chronic helicobacter pylori gastritis. such cases frequently respond to antibiotics directed against h. pylori. antigen-driven lymphomatous disease can also be seen in the association of borrelia burgdorferi with malt lymphoma of the skin, chlamydia psittaci wi ... | 2006 | 16507274 |
re: evidence for an association between chlamydia psittaci and ocular adnexal lymphomas. | 2006 | 16507837 | |
chlamydia psittaci in ocular adnexal lymphoma: japanese experience. | we searched for the chlamydia psittaci dna the touchdown enzyme time release pcr (tetr-pcr) in 23 specimens from 21 patients with ocular adnexal lymphoproliferative disorders, including 12 patients with malt lymphoma to identify c. psittaci infection. southern hybridization of the pcr product using the c. psittaci-specific probe failed to detect c. psittaci, although three samples appeared to be positive by ethidium bromide staining. this indicates that technical approach for detecting c. psitta ... | 2006 | 16524626 |
development of a real-time pcr for the detection of chlamydia psittaci. | 2006 | 16533998 | |
chlamydiae modulate gamma interferon, interleukin-1 beta, and tumor necrosis factor alpha receptor expression in hela cells. | chlamydia psittaci was found to modulate receptor expression for the cytokine receptors that are involved in the synergistic induction of indoleamine dioxygenase in epithelial cells. increases in receptor expression were seen even with inactivated chlamydia, suggesting that chlamydial antigens and not products of infection are important for up-regulating cytokine receptor expression. | 2006 | 16552084 |
[comparative studies on detection of chlamydophila psittaci and chlamydophila abortus in meat turkey flocks using cell culture, elisa, and pcr]. | the prevalence of chlamydia in 10 meat turkey flocks was investigated. as samples served of each moment of collection and sex of the animals 10 cloacal swabs which were taken at the age of 1, 4, 8 and 12 (females) or 16 weeks (males) and at the time of slaughter at the age of 16 or 20 weeks. spleen samples were taken at the time of slaughter, additionally. these were pooled making 1 pool out of 5 individual samples. the cloacal and spleen pools were examined by nested pcr (npcr), capture-elisa a ... | 2006 | 16555483 |
prevalence of chlamydiae in boars and semen used for artificial insemination. | although there are indications for venereal transmission of chlamydiae in pigs, direct diagnostic evidence on the presence of these bacteria in boars and boar semen in particular is still incomplete. we investigated boars from two studs (a, b) in semen (a: n = 174; b: n = 100) and faeces (a: n = 174; b: n = 24) for chlamydiae using ompa-pcr and partial ompa gene sequencing. additionally, blood serum was examined for chlamydial antibodies using an indirect elisa (a: n = 171; b: n = 62). chlamydia ... | 2006 | 16280160 |
a monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates chlamydophila psittaci from chlamydophila pecorum, chlamydophila pneumoniae, and chlamydia trachomatis. | lipopolysaccharide (lps) of chlamydophila psittaci but not of chlamydophila pneumoniae or chlamydia trachomatis contains a tetrasaccharide of 3-deoxy-alpha-d-manno-oct-2-ulopyranosonic acid (kdo) of the sequence kdo(2-->8)[kdo(2-->4)] kdo(2-->4)kdo. after immunization with the synthetic neoglycoconjugate antigen kdo(2-->8)[kdo(2-->4)]kdo(2-->4) kdo-bsa, we obtained the mouse monoclonal antibody (mab) s69-4 which was able to differentiate c. psittaci from chlamydophila pecorum, c. pneumoniae, and ... | 2006 | 16282606 |
pathogenic interactions between chlamydophila psittaci and avian pneumovirus infections in turkeys. | both chlamydophila psittaci and avian pneumovirus (apv) are highly prevalent in belgian turkeys and might contribute to the respiratory disease complex observed in turkeys. initial outbreaks of chlamydiosis occur mostly at the age of 4-8 weeks, often accompanied by an apv infection in apv non-vaccinated farms. regardless apv vaccination, breakthroughs of apv infection from 8 weeks on do occur, a period when also a second c. psittaci infection appears. therefore, this study examined the pathogeni ... | 2006 | 16326044 |
association between helicobacter pylori infection and malt-type lymphoma of the ocular adnexa: clinical and therapeutic implications. | the prevalence and the clinical impact of gastric helicobacter pylori (hp) infection, as well as its possible correlation with chlamydia psittaci (cps) infection and the lymphoma regression rate produced by hp eradicating antibiotic therapy were investigated in patients with malt-type lymphoma of the ocular adnexa (oal). | 2006 | 16385613 |
ocular adnexal lymphoma: a clinicopathologic study of a large cohort of patients with no evidence for an association with chlamydia psittaci. | non-hodgkin lymphomas are among the most common primary tumors occurring in the ocular adnexa. herein, we present a 14-year single-institution experience in 62 patients with primary ocular adnexal lymphomas (oals). association with chlamydia psittaci infection is examined in 57 tumor specimens. extranodal marginal zone lymphoma (emzl) was the most frequent histologic subtype (89%). the majority of patients with emzl (84%) presented with stage e-extranodal (ie), however only 16% had an advanced s ... | 2006 | 16166588 |
cpg motifs as adjuvant in dna vaccination against chlamydophila psittaci in turkeys. | plasmid dna (pcdna1::momp) expressing the major outer membrane protein (momp) of an avian chlamydophila psittaci serovar d strain and recombinant momp (rmomp) with or without the immunomodulating cpg oligonucleotides (cpg on) were tested for their ability to elicit an immune response and to induce protection in turkeys against homologous challenge. two cpg on were chosen for in vivo application based on their in vitro capacity to stimulate the production of nitric oxide (no) in chicken macrophag ... | 2006 | 16183176 |
is there an association between ocular adnexal lymphoma and infection with chlamydia psittaci? the university of rochester experience. | various subsets of extranodal marginal zone lymphomas of mucosa-associated lymphoid tissues (malt lymphomas) have been associated with infectious organisms. most notable of these is the association of gastric malt lymphomas with helicobacter pylori infection. in a recent publication ferreri et al. [ferreri aj, guidoboni m, ponzoni m, de conciliis c, dell'oro s, fleischhauer k, et al. evidence for an association between chlamydia psittaci and ocular adnexal lymphomas. j natl cancer inst 2004;96:5 ... | 2006 | 16246419 |
associations between chlamydophila infections, schizophrenia and risk of hla-a10. | several microbes have been suspected as pathogenetic factors in schizophrenia. we have previously observed increased frequencies of chlamydial infections and of human lymphocyte antigen (hla)-a10 in independent studies of schizophrenia. our aim here was to analyze frequencies of three types of chlamydiaceae in schizophrenic patients (n=72), random controls (n=225) and hospital-patient controls (n=36), together with hla-a genotypes. patients were diagnosed with schizophrenia according to diagnost ... | 2007 | 17102800 |
a pmp genes-based pcr as a valuable tool for the diagnosis of avian chlamydiosis. | in a previous study we described the use of a new set of pcr primers (cpsia/cpsib) specific of the conserved pmp-family genes of chlamydophila abortus as an efficient tool for the detection of these bacteria in ruminants including also preliminary results on avian strains. in this work, the use of this set of primers was extended to representative strains of the six major avian serovars (serovars a-f) and to field isolates of c. psittaci. for all the studied representative strains, using purifie ... | 2007 | 17169505 |
co-infection with two chlamydophila species in a case of fulminant myocarditis. | the aim of this study is to describe a case of fulminant myocarditis caused by co-infection with chlamydophila pneumoniae and chlamydophila psittaci in order to facilitate diagnosis and clinical management of patients suffering from this rare but life-threatening condition. | 2007 | 17204998 |
lack of microbial dna in tissue specimens of patients with abdominal aortic aneurysms and positive chlamydiales serology. | in a case-control study that included a total of 98 patients and 83 controls, the possible link between various pathogens and abdominal aortic aneurysms was investigated. for 68 patients with abdominal aortic aneurysm and age-matched controls, no differences were detected in the levels of immunoglobulin (ig)a and igg chlamydiaceae and chlamydophila pneumoniae antibodies. patients with iga titers positive for chlamydophila pneumoniae showed progressive disease (defined as an annual increase of th ... | 2007 | 17216421 |
absence of chlamydial infection in japanese patients with ocular adnexal lymphoma of mucosa-associated lymphoid tissue. | ocular adnexal extranodal marginal zone b-cell lymphomas of mucosa-associated lymphoid tissue (ocular adnexal malt lymphoma) are predominately low-grade, small b-cell types and may be caused by several putative inflammatory agents. twenty-three ocular adnexal malt lymphoma cases, the monoclonality of which was confirmed by examination of immunoglobulin heavy chain gene rearrangement and/or cell surface antigens, were analyzed for evidence of several causative factors. a serologic evaluation of o ... | 2007 | 17483059 |
[detection of some zoonotic agents in the domestic pigeon (columba livia) in the city of chillán, chile]. | there is an increase in the population of doves (columba livia) as well as their contact with healthy and immunocompromised hosts. | 2007 | 17554438 |
malt lymphoma : recent advances in aetiology and molecular genetics. | mucosa-associated lymphoid tissue (malt) lymphoma is a common low grade b-cell lymphoma arising from a background of chronic inflammatory disease at a number of mucosal sites. those originating in the stomach are causatively linked to helicobacter pylori infection and eradication of the bacterium with antibiotics leads to long-term complete regression of the lymphoma in aproximately 70% of cases. now, there is further evidence of linking campylobacter jejuni, borrelia burgdorferi and chlamydia p ... | 2007 | 18040143 |
a dutch case of atypical pneumonia after culling of h5n1 positive ducks in bavaria was found infected with chlamydophila psittaci. | 2007 | 18053568 | |
serological profiling with chlamycheck, a commercial multiplex recombinant antigen western blot assay of chlamydial infections. | a new chlamydial test system, the chlamycheck assay, which uses 4 purified recombinant antigens of chlamydia trachomatis and chlamydophila pneumoniae and one antigen of chlamydophila psittaci, has been developed and commercialized. we investigated the reactivities of the recombinant antigens with sera from a group of 30 patients with acute chlamydia trachomatis infection, 88 patients consulting for sexually transmitted infections, and 46 patients with serological evidence of chlamydophila pneumo ... | 2007 | 18059568 |
chlamydophila psittaci transmission from pet birds to humans. | we studied zoonotic transmission of chlamydophila psittaci in 39 breeding facilities for psittaciformes (cockatoos, parrots, parakeets, lories) that frequently used antimicrobial drugs. genotypes a or e/b were detected in 14.9% of humans at these facilities. information on antimicrobial drug use in psittaciformes and a c. psittaci vaccine are urgently required. | 2007 | 18214194 |
local cluster of psittacosis after bird show in the netherlands, november 2007. | 2007 | 18082112 | |
[a contribution to the nomenclature and classification of chlamydiae]. | the results of molecular-genetic study of typical specimens of the genus chlamydophila of the family chlamydiaceae from the fse fctrsa collection of microorganisms are considered for the purpose of their taxonomy based on comparative analysis by the omp1-, omp2-, 16s rrna-, and 23s rrna-genes and by the presence of extrachromosomal plasmid with corresponding fragments of the genomes officially registered species of chlamydiae. according to the omp1-rflp-alui-profile, the rostinovo-70, 250, pp-87 ... | 2007 | 18154077 |
[molecular genetic characterization of avian chlamydophila psittaci isolates]. | restriction enzyme analysis of the omp1 gene was used to characterize 51 avian chlamydophila psittaci isolates. the analysis confirmed the predominance of genotype a in parrot c. psittaci isolates and revealed new omp1 genotypes in corvid c. psittaci isolates. the corvid isolates proved to lack an extrachromosomal plasmid. the omp1 and rrna igs sequences were determined for the new isolates. phylogenetic analysis showed that isolate 1v, obtained from a crow, is intermediate in several characters ... | 2007 | 18186183 |
extranodal marginal zone b-cell lymphomas of the ocular adnexa: multiparameter analysis of 34 cases including interphase molecular cytogenetics and pcr for chlamydia psittaci. | extranodal marginal zone b-cell lymphomas of malt type (malt lymphomas) show site-dependent variations in their morphologic, phenotypic, and/or cytogenetic findings. this report describes a comprehensive analysis of 34 ocular adnexa malt lymphomas, including interphase fluorescence in situ hybridization for malt lymphoma-associated cytogenetic abnormalities and polymerase chain reaction for chlamydia psittaci, which has recently been suggested to be associated with ocular adnexa lymphomas. a typ ... | 2007 | 17460465 |
chlamydiae and atherosclerosis: can psittacine cases support the link? | atherosclerosis is a common disease in pet birds, particularly in psittacines. little is known about the role of risk factors predisposing birds to this disease. in our study, we tried to detect chlamydiae in formalin-fixed and paraffin-embedded atherosclerotic tissue from 103 pet birds to clarify their role in atherosclerosis. methods used were polymerase chain reaction (pcr), sequencing, and immunohistochemistry. histopathologic examination served to classify the extent of atherosclerotic lesi ... | 2007 | 17461260 |
evaluation of two commercial assays for the detection of chlamydophila abortus antibodies. | two commercial enzyme-linked immunosorbent assays (elisa), the chekit-chlamydia which uses inactivated chlamydophila psittaci antigen, and the chlamydophila abortus elisa produced by the institut pourquier which uses a recombinant fragment of the 80-90 kda protein, were evaluated with the objective to determine whether the new elisas would perform as improved alternatives to the complement fixation test (cft) for the serological diagnosis of ovine enzootic abortion (oea). the results were compar ... | 2007 | 17382493 |
immune-mediated hemolytic anemia in an eclectus parrot. | a 2-year-old female solomon island eclectus parrot (eclectus roratus) was evaluated by a veterinarian because of a 4-day history of progressive lethargy, weakness, poor appetite, and inactivity. the bird was referred to a veterinary teaching hospital for further examination. | 2007 | 17397343 |
[two familial cases of psittacosis]. | we report here 2 cases of psittacosis in a family. in the first case, a 51-year-old woman was admitted with fever, dry cough, and a chest radiograph showed increased opacity in the right upper lung field. on a diagnosis of atypical pneumonia, minocycline was given and her clinical symptoms and abnormal laboratory data were improved. the second case was her husband, a 58-year-old man who presented with fever 4 days after his wife's admission. his chest radiograph revealed increased opacity in the ... | 2007 | 17419438 |
lack of an association between chlamydia psittaci and ocular adnexal lymphoma. | the objective of this study was to assess whether there is pcr evidence for c. psittaci dna in ocular adnexal lymphoma specimens collected in an academic institution in the u.s. this was a retrospective, single-center study of patients from 1994 - 2004. we used 28 ocular adnexal lymphoma biopsy specimens from adult patients, 16 control lymphoma specimens from patients with systemic lymphomas not involving the ocular adnexa, and five control benign adnexal tissue samples. the presence of c. psitt ... | 2007 | 17454602 |
chlamydia psittaci, helicobacter pylori and ocular adnexal lymphoma-is there an association? the german experience. | 2007 | 17257672 | |
multiple sites of exposure in an outbreak of ornithosis in workers at a poultry abattoir and farm. | cases of ornithosis amongst workers on a rural duck abattoir and farm were notified from late 2003 to health authorities in victoria, australia. in may 2004 we conducted a serological survey to identify the extent of exposure to chlamydophila psittaci amongst workers and a case control study to identify high-risk work areas for ornithosis-related pneumonia. some workers in all occupational groups showed serological evidence of exposure, while those with pneumonia were more likely to have worked ... | 2007 | 17274860 |
low prevalence of chlamydia psittaci in ocular adnexal lymphomas from cuban patients. | most ocular adnexal lymphomas (oal) are extranodal marginal zone b-cell lymphomas (emzl) of mucosa-associated lymphoid tissue (malt)-type. chronic antigen stimulation has been suggested to have a pathogenetic role in emzl and chlamydia psittaci chronic infection has been recently associated with the development of oal in a series of patients from italy. to assess this association, an evaluation of the presence of c. psittaci was made in a different oal population. dna samples were obtained from ... | 2007 | 17325853 |
chlamydia psittaci infection and clinicopathologic analysis of ocular adnexal lymphomas in korea. | ocular adnexal lymphoma (oal) is a mostly extranodal marginal zone lymphoma (emzl). recent findings have suggested an association between chlamydia psittaci (cp) infection and oal. we sought to confirm this issue and to analyze the clinicopathologic characteristics of oal in korea. between 1993 and 2004, 33 oal cases were identified at the asan medical center, seoul, korea. dna was extracted from paraffin-embedded tissues, and touchdown enzyme time release polymerase chain reaction was performed ... | 2007 | 17570512 |
marginal-zone lymphoma. | the term marginal-zone lymphoma (mzl) encompasses three closely related lymphoma subtypes, namely the "low-grade b-cell lymphoma of malt type" currently named malt lymphoma, the "nodal marginal-zone b-cell lymphoma" and a provisional entity in the real classification named "primary splenic mzl with or without villous lymphocytes". these entities display different characteristics, with evident clinical and biological variations according to the organ where the lymphoma arises. marginal-zone b-cel ... | 2007 | 17583528 |
meta-analyses of the association between chlamydia psittaci and ocular adnexal lymphoma and the response of ocular adnexal lymphoma to antibiotics. | there are conflicting reports regarding the association between chlamydia psittaci (cps) and ocular adnexal lymphoma (oal) and the efficacy of antibiotics for oal. in the current study, the authors attempted to clarify the association between cps and oal and the efficacy of antibiotics for oal. | 2007 | 17594698 |
reovirus infections associated with high mortality in psittaciformes in the netherlands. | in the netherlands between january 2002 and december 2004, numerous psittaciformes died showing severe splenomegaly and hepatomegaly with multifocal acute necrosis. at the start of the outbreaks mostly parakeets were affected, but later larger parrots were also involved. seventy-eight birds showed the same features and six were examined completely, including a virological examination. tests for polyomavirus, pacheco's disease (herpesvirus) and circovirus psittacine beak and feather disease (pbfd ... | 2007 | 17620175 |
effect of ovotransferrin and lactoferrins on chlamydophila psittaci adhesion and invasion in hd11 chicken macrophages. | the effect of ovotransferrin (ovotf), human lactoferrin (hlf) and bovine lactoferrin (blf) on the obligate intracellular pathogen chlamydophila (cp.) psittaci was evaluated using a model of buffalo green monkey kidney (bgm) cells and hd11 chicken macrophages as artificial hosts. firstly, the effect of transferrins on the infectivity of the bacteria was evaluated. pre-incubation of cp. psittaci with 0.5 to 5 mg/ml ovotf prior to infecting bgm cells significantly lowered the infection rate (p < 0. ... | 2007 | 17621441 |
investigation on the agonistic and antagonistic biological activities of synthetic chlamydia lipid a and its use in in vitro enzymatic assays. | the synthetic 1,4'-bisphosphorylated penta-acyl and tetra-acyl lipid a structures representing the major molecular species of natural chlamydial lipid a were tested for their endotoxic activities as measured by interleukin-8 release from human embryonic kidney (hek) 293 cells expressing toll-like receptor (tlr) 2 or tlr4. both compounds were unable to activate hek293 cells transiently transfected with tlr2. the penta-acyl lipid a was a weak activator of hek293 cells expressing tlr4/md-2/cd14 whe ... | 2007 | 17621554 |
q fever community-acquired pneumonia in a patient with crohn's disease on immunosuppressive therapy. | community-acquired pneumonia (cap) may be caused by typical or atypical pathogens. the three most common zoonotic atypical pathogens are chlamydophila psittaci (psittacosis), francisella tularensis (tularemia), and coxiella burnetii (q fever). atypical caps are suggested by a distinctive pattern of extrapulmonary organ involvement. zoonotic cap may be differentiated from nonzoonotic cap (chlamydia pneumoniae, mycoplasma pneumoniae, legionnaire's disease) by a recent zoonotic vector contact histo ... | 2007 | 17628200 |
construction and immunogenicity of recombinant adenovirus expressing the major outer membrane protein (momp) of chlamydophila psittaci in chicks. | avian chlamydiosis is caused by chlamydophila psittaci. the major outer membrane protein (momp) encoded by the outer membrane protein 1 (omp1) gene is an excellent candidate for genetic engineering of a vaccine against avian chlamydiosis. in this study, the momp gene was amplified by pcr and cloned into the transfer vector pshuttle-cmv. the recombinant plasmid was obtained by recombination between the plasmid pshuttle-cmv-momp and skeleton vector padeasy-1 in escherichia coli strain bj5183. the ... | 2007 | 17640776 |
the p47 gtpases iigp2 and irgb10 regulate innate immunity and inflammation to murine chlamydia psittaci infection. | c57bl/6j mice were 10(5)-fold more resistant to chlamydia psittaci infection than dba/2j mice by ld(100) determinations. linkage analysis using bxd recombinant inbred strains revealed a single effector locus at a 1.5-mbp region on chromosome 11 encoding a cluster of three p47 gtpases (irgb10, igtp, and iigp2). western blots of infected tissue showed that irgb10 was elevated in resistant mice and one of the two possible iigp2 protein isoforms was preferentially expressed in susceptible mice. the ... | 2007 | 17641048 |
chlamydophila psittaci genotype e/b transmission from african grey parrots to humans. | thirty-six birds from a parrot relief and breeding centre, as well as the manager, were examined for the presence of chlamydophila psittaci. in the relief unit, 5 of 20 african grey parrots showed depression, ruffled feathers, loss of weight and mild dyspnoea. the birds received no antibiotic treatment. birds of the breeding unit, 14 blue and gold macaws and 2 green-winged macaws, were healthy. they received doxycycline at the start of each breeding season. the manager complained of shortness of ... | 2007 | 17644718 |
serologic investigation of the prevalence of chlamydophila psittaci in occupationally-exposed subjects in eastern sicily. | the aim of the study was to investigate the occurrence of serum antibodies to c. psittaci in workers at 8 stock farms located in a rural area of eastern sicily. serum samples from 188 workers and 160 controls were tested for immunoglobulin iga, igg and igm direct against c. psittaci by microimmunofluorescent test (mif). seropositive subjects were defined as those with igg titres of 1:16-1:256, and seronegative subjects as those whose titre was <1:16. to rule out the presence of cross reactive an ... | 2007 | 17655184 |
detection of chlamydophila psittaci antibodies from captive birds at the ninoy aquino parks and wildlife nature center, quezon city, philippines. | the present study was undertaken to detect the presence of chlamydophila psittaci antibodies in captive birds at the wildlife rescue center, ninoy aquino parks and wildlife nature center, quezon city, philippines. blood was collected from 36 birds of different species and the presence of antibodies against c. psittaci was detected using an elisa-based test kit. 25% of the samples demonstrated antibodies against c. psittaci. the results of this study confirmed the presence of c. psittaci antibodi ... | 2007 | 17655198 |
[sporadic forms of ornithosis (psittacosis) in a clinician's practice]. | for a long time ornithosis has been considered an occupational disease, while the significance of sporadic (home) forms of the illness has been underestimated due to difficult clinical diagnostics which results from polymorphic clinical manifestations and the absence of appropriate epidemiological data in home cases of the disease. sporadic ornithosis (psittacosis) is a pathology which is spread widely enough and whose diagnosis is very difficult. one of the most typical manifestations is pulmon ... | 2007 | 17665610 |
lymphoproliferative disease of the orbit. | malignant lymphoma of the ocular adnexa has been reported on for many years, but many steps forward have been recently made. this paper highlights the staging strategies and treatment options based on a review of the most updated and relevant bibliography. | 2007 | 17700233 |
chlamydophila psittaci dna detection in the faeces of cage birds. | in this study, we investigated the shedding of chlamydophila psittaci in faecal samples from cage birds using pcr testing. a total of 47 faeces samples were collected from four different aviaries. main symptoms determined after clinical investigation and owner histories of the birds showed that the birds had respiratory system problems changing from mild to severe. they also showed conjunctivitis, diarrhoea or no symptoms at all. dna extractions from faeces were performed with the qiaamp dna sto ... | 2007 | 17803512 |
a woman and her canary: a tale of chlamydiae and lymphomas. | 2007 | 17848672 | |
microbiological aspects of bacterial lower respiratory tract illness in children: atypical pathogens. | 'atypical' lower respiratory tract pathogens often cause a distinct identifiable syndrome in adults, but in children the clinical presentation of atypical, typical and viral pneumonia is less well differentiated. specific microbiological investigations are usually required, but an understanding of their strengths and weaknesses is necessary to make interpretation possible. this review examines clinical presentation, microbiology and current evidence surrounding diagnostic techniques for mycoplas ... | 2007 | 17868919 |
chlamydiae and mycoplasma infections in pulmonary malt lymphoma. | chlamydia pneumoniae, chlamydia trachomatis and chlamydia psittaci were detected at low frequencies (<20%) among 69 pulmonary mucosa-associated lymphoid tissue (malt) lymphomas, 30 other lymphoproliferative disorders (lpd) and 44 non-lpd. the incidence of individual chlamydiae was generally higher in malt lymphoma than non-lpd, although not reaching statistical significance. mycoplasma pneumoniae dna was not detected. | 2007 | 17876330 |
frequency of development and associated physiological cost of azithromycin resistance in chlamydia psittaci 6bc and c. trachomatis l2. | azithromycin is a major drug used in the treatment and prophylaxis of chlamydial infections. spontaneous azithromycin-resistant mutants of chlamydia psittaci 6bc were isolated in vitro in the plaque assay at a frequency of about 10(-8). isogenic clonal variants with a(2058)c, a(2059)g, or a(2059)c mutations in the unique 23s rrna gene (escherichia coli numbering system) displayed mics for multiple macrolides (i.e., azithromycin, erythromycin, josamycin, and spiramycin) at least 100 times higher ... | 2007 | 17908942 |
infectious disease associations in advanced stage, indolent lymphoma (follicular and nonfollicular): developing a lymphoma prevention strategy. | eradication of helicobacter pylori in gastric mucosa-associated lymphoid tumor can result in lymphoma remission. we prospectively identified/treated infections in nonbulky, advanced stage indolent lymphoma (follicular; nonfollicular lymphoma) eligible for observation. materials and methods: stool h. pylori, hepatitis c and borrelia serologies, borrelia and chlamydia fixed tissue pcr, chlamydia peripheral blood mononuclear cell pcr and hydrogen breath test for small bowel bacterial overgrowth (sb ... | 2008 | 17965114 |
ocular adnexal malt lymphoma: an intriguing model for antigen-driven lymphomagenesis and microbial-targeted therapy. | non-hodgkin's lymphomas constitute one half of malignancies arising in the orbit and the ocular adnexae. mucosa-associated lymphoid tissue (malt)-type lymphoma is the most common histological category in this anatomic region. the incidence of ocular adnexal lymphoma of mucosa-associated lymphoid tissue-type (oaml) is increasing and recent studies offered new relevant insights in molecular, pathogenetic and therapeutic issues on these neoplasms. a pathogenetic model of antigen-driven lymphoprolif ... | 2008 | 17986622 |
evaluation of a chlamydophila psittaci infection diagnostic platform for zoonotic risk assessment. | reports on zoonotic transmission of chlamydophila psittaci originating from poultry are incidentally published. during recent studies in european turkeys we isolated c. psittaci genotypes a, b, d, e, f, and e/b, all considered potentially dangerous for humans. this encouraged us to analyze the zoonotic risk on a belgian turkey farm, from production onset until slaughter, using a chlamydophila psittaci diagnostic platform. twenty individually marked hens, as well as the farmer and two scientists, ... | 2008 | 18003799 |
ten years of viral and non-bacterial serology in adults with cystic fibrosis. | viral infections are associated with pulmonary exacerbations in children with cystic fibrosis (cf), but few studies have addressed the frequency in adults. this paper investigates the frequency and impact of viral infections in adults with cf receiving intravenous antibiotics. pre- and post-treatment spirometry, inflammatory markers and antibody titres against influenza a, influenza b, adenovirus, respiratory syncytial virus, mycoplasma pneumoniae, chlamydia psittaci, and coxiella burnetti were ... | 2008 | 17352838 |
emerging role of chlamydia and chlamydia-like organisms in adverse pregnancy outcomes. | this review considers the roles of chlamydia spp. and newly identified chlamydia-like organisms in miscarriage, stillbirths and preterm labour in both animals and humans. | 2008 | 18192789 |
treatment of mucosa-associated lymphoid tissue-type ocular adnexal lymphoma. | new data have recently been reported in ocular adnexal lymphomas (oals), particularly of mucosa-associated lymphoid tissue (malt)-type, regarding their biological characteristics and therapeutic management. a possible association between oal and chlamydia psittaci infection has suggested new mechanisms of lymphomagenesis and opened the way for specific targeted treatment. similarly, the place of rituximab monoclonal antibody therapy and more conventional chemotherapy, as well as a 'wait-and-see' ... | 2008 | 18594208 |
evaluation of the prophylactic use of ovotransferrin against chlamydiosis in spf turkeys. | chlamydophila (c.) psittaci infections are highly prevalent in turkeys and the economical and public health importance of these infections has been recognized since 1950. as there are no vaccines, antibiotic treatment (tetracylines, enrofloxacine) is often needed to allow marketing of poultry. in this study, we explored the use of ovotransferrin (ovotf), a natural anti-microbial protein, in preventing an experimental c. psittaci infection in specific pathogen free (spf) turkeys. turkeys were tre ... | 2008 | 18603383 |
multiple chlamydiaceae species in trachoma: implications for disease pathogenesis and control. | chlamydia trachomatis is a unique obligate intracellular bacterium that remains the leading cause of sexually transmitted bacterial diseases and preventable blindness worldwide. chronic ocular infections are referred to as trachoma, and predominate in developing countries. since 2001, the world health organization has promoted control strategies including antibiotics, improved hygiene, and environmental measures with limited success. consequently, a vaccine is urgently needed. integral to vaccin ... | 2008 | 18177205 |
real-time pcr detection and quantitation of chlamydophila psittaci in human and avian specimens from a veterinary clinic cluster. | we report three cases of psittacosis in staff working in a veterinary surgery, which was related to exposure to a sick, wild psittacine bird. chlamydial genus- and chlamydial species-specific dna was detected in clinical specimens, including throat swabs, whole blood and urine. the organism load was quantified by real-time pcr (rt-pcr), which revealed 10(5)-fold more organisms in conjunctival swabs from the source bird than in the human samples. one clinic attendant was infected despite using pe ... | 2008 | 18183441 |
genotyping of chlamydophila psittaci using a new dna microarray assay based on sequence analysis of ompa genes. | the currently used genotyping system for the avian zoonotic pathogen chlamydophila (c.) psittaci has evolved from serology and is based on ompa sequence variations. it includes seven avian and two non-avian genotypes. restriction enzyme cleavage of the amplified ompa gene and, less frequently, ompa sequencing are being used for examination, but, beside methodological limitations, an increasing number of recently tested strains could not be assigned to any established genotype. | 2008 | 18419800 |
isolation and characterization of chlamydophila psittaci isolated from laying hens with cystic oviducts. | the objective of this study was to isolate and identify a hypothetical chlamydiaceae pathogen from laying hens with an oviduct cyst, and to characterize its potential causal relation with decreased egg production. our clinical survey showed that cystic oviducts were prevalent at rates of 10% and 15.1% in breeder and commercial hen flocks, respectively. chlamydial antigens were detected in 20 of 50 pharyngeal swabs (40%) and in 17 of 20 oviduct tissues (85%) using enzyme-linked immunosorbent assa ... | 2008 | 18459300 |
health evaluation of free-ranging humboldt penguins (spheniscus humboldti) in peru. | as part of ongoing ecological studies of humboldt penguins (spheniscus humboldti) at punta san juan, ica department, peru, health surveys were conducted in november 1992, 1993, and 1994. in the three surveys, 98 birds in total were handled for examination, and blood was collected for laboratory analysis from 90 of these birds. all birds seemed to be in good condition. body weights of females were significantly lower in 1994 than in the other years. fleas (parapsyllus humboldti) and ticks (ornith ... | 2008 | 18459309 |
ocular adnexal lymphoma: no evidence for bacterial dna associated with lymphoma pathogenesis. | ocular adnexal lymphomas (oals) are the most common tumors of the eye, the majority being extranodal mucosa-associated lymphoid tissue (malt) lymphomas. association with chlamydia psittaci was described in some geographic areas. oal response to antibiotic therapy was reported in cases not harboring chlamydia psittaci dna, suggesting that other bacterial infection might be implicated in the pathogenesis. we examined 49 malt oals for bacterial dna using two distinct polymerase chain reaction techn ... | 2008 | 18492114 |
chlamydophila psittaci is viable and infectious in the conjunctiva and peripheral blood of patients with ocular adnexal lymphoma: results of a single-center prospective case-control study. | ocular adnexal malt lymphoma (oaml) is linked to chlamydophila psittaci (cp) infection. viability and infectivity of cp, demonstrated by growth in culture, has not been yet investigated in these patients. we conducted a single-center prospective case-control study to assess the prevalence, viability and infectivity of cp in 20 oaml patients and 42 blood donors registered in a 6-month period. the presence of cp in conjunctival swabs and peripheral blood mononuclear cells (pbmc) of patients and do ... | 2008 | 18528860 |
local newspaper as a diagnostic aid for psittacosis: a case report. | 2008 | 18540809 | |
the role of infectious agents in the etiology of ocular adnexal neoplasia. | given the fact that infectious agents contribute to around 18% of human cancers worldwide, it would seem prudent to explore their role in neoplasms of the ocular adnexa: primary malignancies of the conjunctiva, lacrimal glands, eyelids, and orbit. by elucidating the mechanisms by which infectious agents contribute to oncogenesis, the management, treatment, and prevention of these neoplasms may one day parallel what is already in place for cancers such as cervical cancer, hepatocellular carcinoma ... | 2008 | 18572051 |
expression of chlamydophila psittaci momp heat-labile toxin b subunit fusion gene in transgenic rice. | a dna fragment encoding the momp gene of chlamydophila psittaci was fused to the heat-labile toxin b subunit gene (ltb-momp) and transferred into rice callus by agrobacterium tumefaciens-mediated transformation. the ltb-momp fusion gene was detected in genomic dna from transformed rice leaves by southern blot and rt-pcr amplification. synthesis and assembly of the ltb-momp fusion protein into pentamers was detected in transformed leaf extracts by immunoblot analysis. binding of the pentamers to ... | 2008 | 18579410 |
chlamydophila spp. infection in horses with recurrent airway obstruction: similarities to human chronic obstructive disease. | recurrent airway obstruction (rao) in horses is a naturally occurring dust-induced disease mainly characterized by bronchiolitis which shows histological and pathophysiological similarities to human chronic obstructive pulmonary disease (copd). in human copd previous investigations indicated an association with chlamydophila psittaci infection. the present study was designed (1) to clarify a possible role of this infectious agent in rao and (2) to investigate the suitability of this equine disor ... | 2008 | 18230187 |
high resolution typing of chlamydophila psittaci by multilocus vntr analysis (mlva). | a multilocus vntr analysis (mlva) system for detection of tandem repeats across the whole genome of chlamydophila psittaci has been developed. twenty selected genetic loci were initially tested on 9 avian reference strains including representatives of all major serotypes (a to f). thereafter, 8 loci were retained for a more complete study performed on over 150 c. psittaci isolates from different bird species and geographical origins. comparative analysis of the mlva results and those obtained fr ... | 2008 | 18242149 |
exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. | to explore the molecular basis of antigen recognition by germline antibodies, we have determined to high resolution the structures of the near-germline monoclonal antibody s25-2 in complex with seven distinct carbohydrate antigens based on the bacterial sugar 3-deoxy-alpha-d-manno-oct-2-ulosonic acid (kdo). in contrast to previous findings, the inherited germline kdo monosaccharide binding site is not restricted to this bacterial sugar but is able to accommodate an array of substitutions and che ... | 2008 | 18272175 |
identification and characterization of a type iii secretion system in chlamydophila psittaci. | chlamydiaceae are obligate intracellular gram-negative bacteria replicating in vacuoles inside eukaryotic cells. it has been proven that most of them possess a type iii secretion system (t3ss) allowing them to transfer effector molecules in the host cell. we examined the existence of a t3ss in chlamydophila psittaci by studying the expression of three essential structural proteins sctw, sctc, and sctn, and one putative effector protein inca. immunofluorescence assays showed sctw and inca to be a ... | 2008 | 18275803 |
[primary ocular adnexal malt lymphoma]. | 2008 | 18277591 | |
iron depletion limits intracellular bacterial growth in macrophages. | many intracellular pathogens infect macrophages and these pathogens require iron for growth. here we demonstrate in vitro that the intracellular growth of chlamydia psittaci, trachomatis, and legionella pneumophila is regulated by the levels of intracellular iron. macrophages that express cell surface ferroportin, the only known cellular iron exporter, limit the intracellular growth of these bacteria. hepcidin is an antimicrobial peptide secreted by the liver in response to inflammation. hepcidi ... | 2008 | 18369153 |
chlamydophila psittaci infections in humans during an outbreak of psittacosis from poultry in germany. | in 2005, an outbreak of severe respiratory disease in a mixed poultry flock that was infected with chlamydophila (c.) psittaci led to dissemination of the infection to at least 100 small poultry farms in 11 districts of central germany. at the same time, a total of 24 persons in contact with poultry from one of the flocks reported flu-like symptoms to their physician, thus suggesting zoonotic transmission. within 3 weeks, seven individuals had to be hospitalized, with three of them requiring int ... | 2008 | 18387139 |
chlamydia psittaci in malt lymphomas of ocular adnexals: the austrian experience. | the presence of chlamydia (c.) psittaci, c. pneumoniae and c. trachomatis dnas in malt lymphomas of ocular adnexals from 13 austrian patients were studied. gastrointestinal malt lymphomas and gastritis specimens served as controls. of 13 malt lymphomas of the ocular adnexals, seven were positive for c. psittaci dna. in contrast, one of 17 gastrointestinal specimens tested positive. all specimens were negative for c. trachomatis and c. pneumoniae dnas. in conclusion, c. psittaci infection was obs ... | 2008 | 18061259 |
chlamydia-psittaci-eradicating antibiotic therapy in patients with advanced-stage ocular adnexal malt lymphoma. | 2008 | 18073219 | |
low potency of chlamydophila lps to activate human mononuclear cells due to its reduced affinities for cd14 and lps-binding protein. | chlamydiaceae are small obligate intracellular parasites and classified as gram-negative bacteria. among chlamydiaceae-derived components, lps is known as an immunomodulator and possesses a unique lipid a structure with longer but fewer acyl chains. in this study, to elucidate the chlamydiaceae-induced immune responses, we evaluated the actions of chlamydophila psittaci lps as a chlamydiaceae lps on human pbmcs and compared with those of escherichia coli lps. similar to e. coli lps, c. psittaci ... | 2008 | 18056918 |
an outbreak of psittacosis in a bird park in japan. | an outbreak of psittacosis related to a bird park occurred in matsue city, shimane prefecture, japan, during winter 2001. seventeen cases of psittacosis (12 visitors, three staff, and two student interns) were confirmed. a cohort study was conducted among the park staff and students to determine the risk factors for the development of acute serologically confirmed psittacosis (scp) infection. being 'bird staff' had an increased risk of scp infection (rr 3.96, 95% ci 1.48-10.58). entering the sta ... | 2008 | 17559693 |
variable association between chlamydophila psittaci infection and ocular adnexal lymphomas: methodological biases or true geographical variations? | since the first publication in 2004, a large number of reports have raised the question of an association between ocular adnexal lymphoma and chlamydia psittaci. the results of this scientific debate, however, remain controversial. the primary objective of this paper was therefore to raise important questions concerning the interpretation of the different and heterogeneous data on the association between chlamydophila psittaci and ocular adnexal lymphoma, namely the impact of the methodology use ... | 2008 | 18690086 |
familial outbreak of psittacosis as the first chlamydia psittaci infection reported from turkey. | psittacosis, also known as parrot disease, parrot fever and ornithosis, can be transmitted to humans by inhaling dried excreta of infected birds like canaries, parakeets, parrots, pigeons and turkeys. unless it is specifically thought of and investigated, the diagnosis of psittacosis can easily be missed and without identifying the exact etiology, the disease is usually treated as atypical pneumonia. we diagnosed psittacosis in a mother and her son with friedreich ataxia, who took care of two pa ... | 2008 | 18701984 |
[rapid diagnosis of psittacosis using a recently developed real-time pcr technique]. | a 37-year-old man was admitted with cough and fever. three days after admission he was tested using a newly developed real-time pcr technique that detects the dna of chlamydophila psittaci. the result was positive; serological investigation was not positive until 14 days later. psittacosis is a potentially life-threatening infectious disease. laboratory diagnosis relies mainly on the assessment of paired sera, but this approach has obvious disadvantages in the acute setting. routine use of the r ... | 2008 | 18788681 |
[an outbreak of psittacosis at a bird-fanciers fair in the netherlands]. | within 2 weeks after a bird-fanciers fair in the netherlands in november 2007 11 patients presented at our hospital with fever, shivers and severe headache. dyspnea and dry cough were less common, although the chest x-ray showed a consolidation in 9 out of 11 patients. the clinical diagnosis of psittacosis was quickly confirmed using real-time pcr, although the sensitivity of this test was low (20%). in 9 patients the diagnosis was later confirmed by a rise in complement fixing antibodies in pai ... | 2008 | 18788682 |
chlamydia infection and lymphomas: association beyond ocular adnexal lymphomas highlighted by multiple detection methods. | chlamydia psittaci (cp) has been associated to ocular adnexal lymphomas (oal) with variable geographic distribution. herein, we used multiple chlamydia detection tools to identify cp elementary bodies-containing cell and to assess cp prevalence in both nodal and extranodal lymphomas. | 2008 | 18794089 |
two fatal cases of psittacosis caused by chlamydophila psittaci. | two fatal cases of psittacosis are described in two poultry-processing-plant employees presenting with pneumonia and respiratory failure. diagnosis was confirmed by serological and pcr methods. psittacosis due to chlamydophila psittaci infection usually has a good recovery rate, although diagnostic delay and mistreatment can lead to severe complications and even death. this report emphasizes the need for rapid differential diagnosis and management of suspected cases of atypical pneumonia to prev ... | 2008 | 18809562 |
diabetes mellitus in a nanday conure (nandayus nenday). | a 3-year-old male nanday conure (nandayus nenday) was presented with acute lethargy, polyuria, and polydipsia. marked persistent hyperglycemia, glycosuria, and ketonuria were also noted. the serum insulin concentration (< 3 microu/ml) was lower than reference ranges described for other psittacine birds. initial treatment included insulin, antibiotics, and supportive care. insulin therapy was adjusted based on results of serial blood glucose curves. histopathologic examination of pancreatic biops ... | 2008 | 19014099 |
preliminary studies on the etiology of keratoconjunctivitis in reindeer (rangifer tarandus tarandus) calves in alaska. | keratoconjunctivitis outbreaks occur each summer in reindeer (rangifer tarandus tarandus) herds in western alaska, usa. this condition has not been well characterized nor has a definitive primary etiologic agent been identified. we evaluated the eyes of 660 calves near nome, alaska, between 29 june and 14 july 2005. clinical signs of keratoconjunctivitis were observed in 26/660 calves (3.9%). samples were collected from the conjunctival sac of both affected (n=22) and unaffected (n=24) animals f ... | 2008 | 18957667 |
comparison of the new inodiag automated fluorescence multiplexed antigen microarray to the reference technique in the serodiagnosis of atypical bacterial pneumonia. | the aetiological diagnosis of pneumonia depends largely on culture-, antigen- or pcr-based tests. atypical agents of pneumonia include coxiella burnetii, chlamydophila pneumoniae, chlamydia psittaci, legionella pneumophila, francisella tularensis and mycoplasma pneumoniae. in these cases, serological tests are commonly used for diagnosis. all of the above species were comparatively screened for by using the inodiag multiplexed automatic immunofluorescence assay and established reference techniqu ... | 2008 | 19076843 |
chlamydophila psittaci seropositivity and serum levels of soluble intercellular adhesion molecule-1 in farmers. | chlamydophila infection is known as an occupational hazard to veterinarians, farmers, poultry workers. serum levels of the soluble intercellular adhesion molecule-1 (sic am-1), is associated with c. seropositivity. since no data about ic am-1 levels and c. psittaci infection are known, the aim of this work was to assess if chronic persistent c. psittaci infection constantly stimulates the expression of sic am-1, independent of the characteristic symptoms of ornithosis. c. psittaci seropositivity ... | 2008 | 19061263 |
ocular adnexal lymphoma and infectious agents. | 2009 | 19075420 | |
chlamydial infection: the link with ocular adnexal lymphomas. | chlamydiae are obligate intracellular bacteria that grow in eukaryotic cells and cause a wide spectrum of diseases. they can establish persistent infections, are mitogenic in vitro, promote polyclonal cell proliferation in vivo and induce resistance to apoptosis in infected cells-properties that might contribute to tumorigenesis. in fact, chlamydophila psittaci (cp) has been linked to the development and maintenance of ocular adnexal marginal zone b-cell lymphoma (oamzl). in this indolent malign ... | 2009 | 19806147 |
genomic analysis of an attenuated chlamydia abortus live vaccine strain reveals defects in central metabolism and surface proteins. | comparative genomic analysis of a wild-type strain of the ovine pathogen chlamydia abortus and its nitrosoguanidine-induced, temperature-sensitive, virulence-attenuated live vaccine derivative identified 22 single nucleotide polymorphisms unique to the mutant, including nine nonsynonymous mutations, one leading to a truncation of pmpg, which encodes a polymorphic membrane protein, and two intergenic mutations potentially affecting promoter sequences. other nonsynonymous mutations mapped to a pmp ... | 2009 | 19596773 |
susceptibility to infection and immune response in insular and continental populations of egyptian vulture: implications for conservation. | a generalized decline in populations of old world avian scavengers is occurring on a global scale. the main cause of the observed crisis in continental populations of these birds should be looked for in the interaction between two factors -- changes in livestock management, including the increased use of pharmaceutical products, and disease. insular vertebrates seem to be especially susceptible to diseases induced by the arrival of exotic pathogens, a process often favored by human activities, a ... | 2009 | 19623256 |
protection of budgerigars (melopsittacus undulatus) against chlamydophila psittaci challenge by dna vaccination. | plasmid dna (pcdna1::momp a) expressing the major outer membrane protein (momp) of chlamydophila psittaci genotype a strain 89/1051 has been tested for its ability to induce protective immunity against cp. psittaci challenge in budgerigars. eight pairs of male and female budgerigars were housed in eight separate bird cages placed in two negative pressure isolators, four cages per group. all budgerigars were immunised twice intramuscularly with 100 microasmid dna. both groups received a primary d ... | 2009 | 19640395 |