Publications

[demonstration of a herpesvirus in amazon parrots (amazona aestiva and a. ochrocephala)].		1980	6255709
lymphocyte-derived chemotactic factor synthesis in initial genital herpesvirus infection: correlation with lymphocyte transformation.	lymphocyte transformation and production of lymphocyte-derived chemotactic factor in response to herpes simplex virus antigen were studied in 15 patients with initial genital herpes and 10 controls. the patients underwent frequent genital examinations, viral cultures, and weekly immunological studies for a period of 11 weeks. the production of lymphocyte-derived chemotactic factor was maximal in week 1 of the disease and declined to control levels by week 6. in contrast, lymphocyte transformatio ...	1980	6254875
quantification of plasminogen activator activity associated with herpesvirus-transformed cells.	herpesvirus-transformed cell lines were examined for plasminogen activator (pa) activity using a quantitative assay. previous results of cold fibrin overlay assays indicated that herpesvirus-transformed hamster cell lines produce fibrinolytic activity. quantification of this activity involved the use of an 125i-fibrin lysis assay in which medium previously incubated with transformed or normal cells was tested for its ability to lyse 125i-fibrin polymers. this assay indicated an enhanced producti ...	1980	6255081
inactivated vaccine for parrot herpesvirus infections (pacheco's disease).	four tests of an inactivated emulsified vaccine against a herpesvirus infection (pacheco's disease) in bodgerigars demonstrated that an effective vaccine could be produced with concentrated virus. virus was propagated in chicken kidney cells, and cells and fluid were harvested 3 to 5 days after inoculation and sonicated. the virus was concentrated 100 x by centrifugation to produce a multiple emulsion vaccine that was protective against im challenge exposure with live virus. the serologic respon ...	1980	6255831
feline respiratory tract disease in louisiana.	an investigation of feline respiratory tract disease (frd) was made involving 65 affected cats (group 1) and 65 control cats (group 2) matched for age, sex, and residence. feline calicivirus strains (fcv), feline herpesvirus-1 (fhv-1), or both, were isolated from 59% of group 1 cats and from 7% of group 2 cats. isolation of these viruses showed a significantly greater (p < 0.05) relative risk for group 1 cats. virus isolations were three times more frequent from males than from females older tha ...	1980	6255833
serologic responses of pregnant thoroughbred mares to vaccination with an inactivated equine herpesvirus 1 vaccine.	the immunogenic potency and safety of a chemically inactivated equine herpesvirus 1 vaccine with added adjuvant was evaluated by testing serum-neutralizing and complement-fixation antibody responses of pregnant thoroughbred mares. the vaccinated population comprised 321 pregnant mares on 7 farms; 3 in normandy, france; 1 in kildare, ireland; and 3 in central kentucky. the pattern of antibody response to vaccination was found qualitatively and quantitatively similar to that of pregnant mares prev ...	1980	6259970
[herpesvirus and human cancer].		1980	6255964
virus-viral co-cancerogenesis and the other viral interactions.	the article presents the data obtained by the authors in studies of virus-viral co-cancerogenesis, the interaction between some non-oncogenic viruses and well-known oncogenic viruses, the results of co-cancerogenic effect marek's disease herpesvirus with the avian leukemia virus and the possibility of phenotype mixing between oncornaviruses belonging to different species in nature.	1980	6257199
herpesvirus hepatitis in rat kangaroos.		1980	6257221
response of pregnant mares to equine herpesvirus 1 (ehv1).	twenty-one pregnant mares were inoculated with ehv1. nineteen became infected as evidenced by clinical signs and/or viremia but only one mare aborted a virus-infected fetus. the viremias were leukocyte-associated and appeared to be non-productive, latent infections of these cells. infectivity, detectable by cocultivation, persisted in the circulating leukocytes for as long as 9 days without resulting in abortion. the data suggest that it is extremely difficult to evaluate the efficacy of vaccine ...	1980	6257449
morphological observations of the replication of herpesvirus tamarinus in rl-33 cells.	the replication in rl-33 cells (rabbit lung cell line) of herpesvirus tamarinus isolated from cotton-topped marmosets (saguinus oedipus) was investigated by electron microscopy. in the early stages of infection, ring-shaped and granular structures, and fibrillar materials were recognized in the nucleus. immature particles were often found in such nuclei. the envelope of the virus was formed by budding through intracytoplasmic membranes, the inner nuclear membrane or the membrane of intracytoplas ...	1980	6254473
bovine dermatotropic herpesvirus infections.		1980	6258043
serological comparison of bovid herpesvirus 2 and herpes simplex virus by reciprocal neutralization kinetic studies.		1980	6258858
attempts to reactivate bovid herpesvirus-2 in experimentally infected calves.	a study was carried out to determine whether bovid herpesvirus-2 (bhv-2) is able to induce a recurrent infection in experimentally infected calves. twelve calves infected with the virus were treated with dexamethasone (dms) beginning 69 days after the infection, ie, several weeks after the animals had recovered from the disease and were negative for bhv-2. the stress induced by dms treatment failed to reactivate the clinical condition or to induce shedding of bhv-2. however, treatment with dms r ...	1980	6259974
lymphocyte responses to virus and mitogen in ponies during experimental infection with equine herpesvirus 1.	six pony foals, experimentally infected with equine herpesvirus 1 (ehv-1), were studied for their lymphocyte responses to ehv-1 and phytohemagglutinin (pha) stimulations. lymphocyte blastic transformation in the presence of ehv-1 appeared as early as 2 days after the foals were inoculated, reached a peak in 7 to 10 days, and subsequently decreased. in contrast, the lymphocyte blastic transformation in the presence of pha increased sharply, reaching a peak in 2 to 3 days, and then decreased to it ...	1980	6259978
[experimentally induced herpesvirus sa 8 -- encephalitis in kenya baboons (papio cynocephalus) (author's transl)].		1980	6259804
herpesvirus saimiri-induced malignant lymphoma in inbred strain iii/j rabbits (oryctolagus cuniculus).	four young strain iii/j rabbits of both sexes were inoculated with a single dose of prototype partially purified herpesvirus saimiri (hvs) via iv and im routes. all inoculated animals had enlarged lymph nodes, and significant levels of antibodies to hvs early, late, and membrane antigens were detectable during the infection. the animals died or were killed and hvs was isolated from the peripheral blood mononuclear cells and the various lymph nodes but not from the kidney. microscopic examination ...	1980	6260812
[histological and ultrastructural changes in calves infected with bovine herpesvirus 2].	we studied the hide, neck knots, as well as the liver of calves infected intradermally with strain kos-haskovo of bovid herpes virus 2. on the spot of the injection we found necrotic changes in the superficial strata of the epidermis, hydropic distrophy of st. spinosum and also eosinophil intranuclear inclusions in separate epithelial cells. intranuclear acidophil inclusions were proved also in the macrophages of the lymph knots, whereas in the liver we found a reactive lithic micronecroses. the ...	1980	6261440
regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes.	herpes simplex virus 1 (hsv-1) specifies in the infected cell a set of polypeptides (alpha) whose mrnas are made in the absence of protein synthesis. the individual mrnas specifying alpha polypeptides 0, 4, 22, and 27 were purified by hybridization to strand-separated or total hsv-1 dna fragments cloned in pbr322 plasmids, translated in vitro to verify their specificity, then mapped by hybridization to separated strands and digests of cloned dna fragments. to map the transcription initiation sit ...	1980	6261240
interaction of herpesvirus with spleen cell subpopulations comparison of a neurotropic and a lymphotropic virus.	we studied the interaction of a neurotropic herpesvirus, herpes simplex virus type 1 (hsv-1) or type 2 (hsv-2), and a lymphotropic herpesvirus, guinea pig herpes-like virus (hlv), with guinea pig spleen cells. both hsv-1 and hsv-2 and hlv can attach to and penetrate into b- or t-enriched cells. less than 1.4% of the total b- or t-enriched cell populations were susceptible to infection by hlv and to some degree to hsv-1 or hsv-2 as determined by infectious center assays. after specific antiserum ...	1980	6262239
comparative studies of herpesvirus papio (baboon herpesvirus) dna and epstein-barr virus dna.	an epstein-barr virus (ebv)-like herpesvirus has been isolated from a baboon cell line (594s/f9) by induction with the tumour promoter 12-o-tetradecanoyl-phorbol-13-acetate (tpa). the herpesvirus papio (hvp) dna was mixed with b95 ebv dna and was characterized by sedimentation in neutral glycerol gradient as 55s dna, with a buoyant density of approx. 1.718 g/ml after equilibrium centrifugation in caesium chloride. dna-dna reassociation kinetics between b95 ebv and hvp dna showed that hvp dna sha ...	1980	6262436
a simple method for typing clinical isolates of herpesvirus simplex: replication in the presence of 2h-1,3-oxazine-2,6 (3h)-dione (oxauracil).	a rapid simple method for the typing of wild hsv isolates based on selective inhibition of hsv-2 replication by the pyrimidine analogue oxauracil (2h-1,3-oxazine-2,6(3h)-dione) has been developed. chi-square analysis of the results of typing of 30 wild strains by serum neutralization tests, immunofluorescence, and oxauracil-inhibition indicates no significant differences in assignment of types to the isolates. the oxauracil-inhibition test obviates confusion of typing resulting from use of immun ...	1980	6262455
comparison of the effect of trisodium phosphonoformate on the mean plaque size of pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus.		1980	6268670
proteins of herpesvirus saimiri: identification of two virus polypeptides released into the culture medium of productively infected cells.	two virus-induced polypeptides are preferentially released into the culture medium of owl monkey kidney cells productively infected with herpesvirus saimiri (hvs). these polypeptides have apparent mol. wt. of 160 x 10(3) and 28 x 10(3) and are the major virus-induced polypeptides in a membrane fraction from infected cells. both these excreted polypeptides co-migrate with virus structural proteins and are selectively released from enveloped virus particles by treatment with nonidet-p40.	1980	6262446
herpesvirus saimiri: protective effect of attenuated strain against lymphoma induction.	an attenuated strain of herpesvirus saimiri (a-hvs) induced a persistent, latent infection in common marmosets. virus was recovered from circulating lymphocytes of infected animals and antibody response to virus-specified antigens was demonstrated over 3-12 months pi. a-hvs-infected common marmosets and animals without previous a-hvs exposure were challenged with oncogenic hvs (125-825 pfu); marmosets without a-hvs infection developed malignant lymphoproliferative disease and died 3 weeks pi whe ...	1980	6265382
bovine herpesvirus type 1 in the sperm of a bull from a herd with fertility problems.	a herd of 125 holstein cows manifested fertility problems for two years. the number of services per pregnancy was 2.97, conception rate was 33% after the first service, and the average number of open days was 127. abortions occurred in four cows over the last 12 months. the herd was not vaccinated against any disease. natural service by a bull and artificial insemination were used for breeding the cows. bovine herpesvirus type 1 was demonstrated in sperm heads from the bull by direct and indirec ...	1980	6266630
effects of infectious bursal disease on marek's disease vaccination: suppression of antiviral immune response.	studies were made to determine whether infectious bursal disease virus (ibdv) infection would affect the response of chickens to turkey herpesvirus (hvt) vaccination in the development and level of hvt viremia and virus-neutralizing (vn) antibodies to hvt. the hvt viremia in the vaccinated chickens was not affected by ibdv, whether ibdv was inoculated simultaneously with hvt vaccination at one day of age or whether it was inoculated 3 weeks postvaccination with hvt. however, vn antibody response ...	1980	6268042
interaction of herpesvirus ateles with marmoset lymphocytes. ii. identification of target cell population and stimulation of dna synthesis after infection in vitro.		1980	6263823
cell-mediated immunity in marek's disease: cytotoxic responses in resistant and susceptible chickens and relation to disease.	two experiments were conducted to study the cell-mediated cytotoxicity of peripheral blood leukocytes (pbl) from chickens inoculated with marek's disease virus (mdv) against a marek's disease-derived lymphoblastoid cell line (msb-1) and to associate the cytotoxicity with incidence of disease. in experiment i, moderately susceptible random-bred, specific-pathogen-free chickens were inoculated with mdv (group 1), vaccinated with a herpesvirus of turkeys (hvt) and inoculated with mdv (group 2), vac ...	1980	6445171
inhibitors of dna synthesis produced by herpesvirus-transformed cell lines.	inhibitory factors were detected in the supernatant fluids of two herpesvirus-transformed lymphoid cell lines, one a b cell line established from a cotton-topped marmoset with ebv-induced lymphoma (1605l) and the other a hvs-transformed marmoset t cell line (c-1 ax). the factors produced by both cell lines inhibited the uptake of 125i-iododeoxyuridine (125i-iudr) by lymphocytes stimulated by both phytohemagglutinin and pokeweed mitogen. both factors also suppressed the uptake of 125i-iudr by cel ...	1980	6445386
in vitro inhibition of herpesvirus sylvilagus by phosphonoacetic acid and phosphonoformate.	phosphonoacetic acid and phosphonoformate were examined as inhibitors of herpesvirus sylvilagus replication in cultured cells. both drugs produced significant inhibition at a minimum concentration of 25 micrograms per milliliter.	1980	6449917
[intensified adsorption of viruses to cell cultures: improved virus isolation? (author's transl)].	two procedures to improve virus cultivation from clinical material were evaluated: an intensified adsorption with 0.2 ml inoculum and 20 h rocking in a bellco rocker and a low-speed centrifugation of the material onto the cultured cells. prototype strains from 5 virus families (adenoviruses, herpes simplex virus, vaccinia virus, enteroviruses, parainfluenza 2) as well as original specimens from patients (adenovirus, herpesvirus, enterovirus) were studied by endpoint titration in comparison with ...	1980	6775453
antibodies to malignant catarrhal fever virus antigens in the sera of normal and naturally infected cattle in kenya.	six different serological tests were used to examine kenyan cattle sera for antibodies to the herpesvirus of malignant catarrhal fever. significantly higher levels of indirect immunofluorescent antibody to early and late virus antigens and of complement fixing antibody were found in the sera of 13 naturally infected cattle than in 482 sera collected from four different groups of normal cattle. virus neutralising and immunoprecipitating antibodies were also found in some infected cattle sera but ...	1980	6781021
interaction of herpesvirus ateles and hepesvirus saimiri with primate lymphocytes. i. selective adsorption of virus by lymphoid cells.	a semiquantitative infectious bioassay, described by sairenji and hinuma for the measurement of epstein-barr virus (ebv) receptors, was adapted to study the adsorption of the lymphotropic new world herpesvirus ateles (hva) to established lymphoid lines and lymphocytes of human versus marmoset origin. all marmoset t-cell lines [hva- or hvs (herpesvirus saimiri)-carrying] had a high adsorbing capacity. ebv-carrying marmoset or human b-cell lines, one ebv-negative human b-lymphoma line, and one hum ...	1980	6766914
poikilotherm vertebrate cell lines and viruses: a current listing for fishes.	a survey of the literature and of work being done in vertebrate cell culture shows that there are currently in existence and available to investigators some 61 cell lines representing 17 families and 36 species of fish. the literature of fish virology shows that at least 17 fish viruses have been isolated and that at least 15 others have been visualized by electron microscopy. a minimum of four major virus groups--rhabdovirus, orthomyxovirus, iridovirus and herpesvirus--are known from fish. orig ...	1980	6767657
derivatives of 3'- and 5'-deoxyadenosine: their inhibitory activity against dna viruses.	3'-deoxyadenosine, 3'-amino-3'-deoxyadenosine (3'3'), nine derivatives therefrom, two derivatives of 5'-amino-5'-deoxyadenosine and three derivates of 3', 5'-dideoxyadenosine were tested in cell culture for antiviral activity against three dna viruses: adenovirus 5, herpesvirus hominis 1, and vaccinia virus. cytotoxicity was also assessed. (3'3') derivatives affected the multiplication of all three viruses similarly. those which were effective were also cytotoxic at the same or slightly higher c ...	1980	6967001
methylation of foreign dna sequences in eukaryotic cells.	the herpesvirus thymidine kinase gene has been used to introduce foreign dna sequences into mouse l cells by dna-mediated gene transfer. these inserted genes were then assayed for methylation at the specific sequence c-c-g-g by using the restriction enzyme isoschizomers hpa ii and msp i. despite the fact that 70% of the cellular c-c-g-g sites are methylated, herpesvirus sequences, plasmid dna, and growth hormone gene dna were found to remain unmethylated in 90% of the clones that contain these g ...	1980	6935661
chemically defined serum-free media for the cultivation of primary cells and their susceptibility to viruses.	chemically defined media sfre-199-1 for the growth and sfre-199-2 for the maintenance of primary baboon kidney (bak) cell cultures were formulated by supplementing medium m199 with insulin, sodium pyruvate, zinc sulfate, and increasing arginine-hcl, cysteine, cystine, l-glutamine, l-glutamatic acid, glycine, histidine, tyrosine, and glucose to maximally active nontoxic concentrations. for prolonged maintenance of the cells, physiological ph control, and blocking of excessive lactic acid accumula ...	1980	6997185
[brain steam encephalitis caused by herpesvirus hominis died of acute respiratory failure--report of a case with autopsy (author's transl)].		1980	7006648
hodgkin's disease with specific bullous lesions.	a variety of bullous eruptions have been reported in patients with hodgkin's disease, among them erythema multiforme, herpesvirus infections, bullous impetigo, prurigo-like papules with vesicles, drug eruptions, bullous pemphigoid, dermatitis herpetiformis, and acquired epidermolysis bullosa. we now describe a patient whose bullous eruption was thought initially to be bullous pemphigoid. however, histopathologic examination of a bulla showed a lymphomatous infiltrate beneath an intraepidermal an ...	1980	7008639
independence of chicken major histocompatibility antigens and tumor-associated antigen on the surface of herpesvirus-induced lymphoma cells.	capping of chicken major histocompatibility (mhc) antigens on normal thymus, spleen, and peripheral blood leukocytes was demonstrated, although mhc antigens appeared to be present on only 15 to 18% of normal thymus cells. mhc antigen capping also occurred on cells from a marek's disease herpesvirus-induced transplantable lymphoma (mdct-nym1). capping of a marek's disease tumor-associated surface antigen (matsa) could be induced on mdct-nym1 lymphoma cells as well as on cells of two marek's disea ...	1980	7000703
blocking of immunofluorescence in the titration of membrane and intracellular reactive antibodies associated with herpesvirus of turkeys.	blocking of the direct immunofluorescence (if) reaction allowed titration of anti-membrane antigen (ma) or anti-intracellular antigen (ia) antibodies induced by herpesvirus of turkeys (hvt). the titers (blocking index) obtained by the blocking if test were well correlated with those determined by the if test. the results suggest that the blocking if test was a simpler and better method for titration of a large number of serum samples from chickens infected with hvt.	1980	7002147
the protection of rabbits against the herpesvirus of malignant catarrhal fever by inactivated vaccines.	cell-free virulent malignant catarrhal fever virus inactivated by either formalin or acetylethylenimine (aei) and administered with freund's complete adjuvant protected rabbits against two consecutive parenteral challenges with cell-free virus. however 'protected' rabbits succumbed within 20 days to later inoculation of infected rabbit lymph node suspensions. both inactivated vaccines evoked high titres of neutralising and immunofluorescent antibody, but more of the rabbits given the aei prepara ...	1980	6997950
diethylstilbestrol-exposed monozygotic twins discordant for cervicovaginal clear cell adenocarcinoma.	monozygotic, 17-year-old, female twins exposed to diethylstilbestrol (des) in utero and discordant for cervicovaginal clear cell adenocarcinoma are reported. benign teratologic changes were present in both. the twin with cancer was treated by extensive operation and postoperative irradiation. no tumor has appeared in either twin in the 4 years subsequent to therapy. discordance for cervicovaginal clear cell adenocarcinoma in this situation suggests that factors other than embryonic exposure to d ...	1980	7189642
humoral and cell-mediated immune response of foals vaccinated with attenuated equine herpesvirus type 1 (ehv-1).		1980	7223181
viruses and cancer risk in man.	the present state of tumor virus research in man is analysed in order to evaluate the cancer risk by viruses in man. for most of the viruses isolated from human tumorous or normal tissues and similar to oncogenic viruses of animals the participation as causative agent in the multifactorial process of cancer induction, promotion and realization in man is not yet established. this holds true for dna viruses (paillomaviruses, sv 40-related viruses, herpesvirus 2, hepatitis b virus) as well as for t ...	1980	7224804
scanning electron microscopy of the tracheal epithelium of calves inoculated with bovine herpesvirus 1.	tracheal epithelium was examined by light, scanning electron and transmission electron microscopy at four, five and seven days after calves were infected intranasally with bovine herpesvirus. similar areas were examined from uninoculated calves. tracheal epithelial lesions were found in all inoculated calves and their degree of severity did not vary with the interval between inoculation and examination. extensive loss of cilia leaving areas of tracheal epithelium covered by microvilli was the ma ...	1980	7255893
fatal massive hepatic necrosis from varicella-zoster hepatitis.	an unusual case of varicella-zoster hepatitis is reported which resulted in fatal massive hepatic necrosis in a 64-year old white female. the patient had had chickenpox 30 years prior to death but no cutaneous zoster at any time. the liver showed typical eosinophilic intranuclear inclusions and herpesvirus virions were demonstrated by electron microscopy. indirect immunofluorescent serologic studies confirmed remote and recent infection by varicella-zoster virus. the potential significance of an ...	1980	7234819
computerized reconstruction of the core of herpesvirus of turkey.		1980	7241008
herpes infections in the immunosuppressed host.	very recent studies indicate that a primitive immune system plays an important role in resisting herpesvirus infections in the mouse. this system appears to be reflected by the nk cell assay and preliminary data suggest that this test reflects resistance in man to herpesvirus infections. we propose that ths system may be responsible for resistance to reactivated herpesvirus infections and its suppression might result in clinically apparent disease. studies in our laboratory are currently aimed a ...	1980	7243213
improvement in plaquing methods for the enumeration of anatid herpesvirus (duck plague virus).	the holland strain of anatid herpesvirus (ahv) was 2-to 10-fold more efficiently plaqued under liquid medium or semisolid medium containing methylcellulose than in media containing agar, agarose, or nobel agar. virus adsorption was complete in 45 min, with the maximum virus titers obtained under liquid medium at 48 h postinfection. the ahv dose-response curve was linear. pekin duck embryo cultures were more efficient than ccl-141 in plaque response and gave the maximum virus yield per cell. viru ...	1980	7251330
combined effects of acycloguanosine and humoral antibodies in experimental encephalitis due to herpesvirus hominis.		1980	7441012
isolation of bovine herpesvirus-1 from trigeminal ganglia of clinically normal cattle.	trigeminal ganglia collected from 56 adult dairy cattle at slaughter were maintained in explant culture. bovine herpesvirus-1 was isolated from six ganglia after periods of 7 to 24 days' maintenance in vitro. antibody against bovine herpesvirus-1, indicating exposure to that virus, was found in 45.4% of the sample population from which ganglia were collected.	1980	7447114
deoxythymidine kinase metabolism in equine herpesvirus type 3 infected horse embryo dermal fibroblasts.		1980	7361458
relation between the neutralization of herpesvirus of turkeys and the antibody to late-appearing membrane antigen induced by the virus.	the relation between the neutralization of herpesvirus of turkeys hvt) and the antibodies to early appearing membrane antigen (ema), late appearing membrane antigen (lma) and intracellular antigen (ia) induced by the virus was examined by blocking of direct immunofluorescence using 38 sera from chickens infected with hvt. our results provide evidence that anti-lma is significant in the neutralization of the infectivity (p less than 0.001) since the neutralizing capacity of the serum was related ...	1980	7365465
locomotor effects of catecholaminergic drugs on herpes-infected mice.	changes in spontaneous, amphetamine (amp) and apomorphine (apo) induced locomotor activity were used to assess the effects of central nervous system (cns) infection with herpes type 1 virus. a dual herpesvirus inoculation procedure was used in which the animals received an immunizing footpad inoculation followed at 2 weeks by an identical intracerebral challenge. four weeks later the animals were tested with intraperitoneal injections of saline or d-l-amphatmine (0.5 and 2.0 mg/kg). when footpad ...	1980	7367463
biochemical characterization of equine herpesvirus type 3-induced deoxythymidine kinase purified from lytically infected horse embryo dermal fibroblasts.	infection of horse kyed cells with equine herpesvirus type 3 (ehv-3) resulted in a sevenfold increase in cytosol deoxythymidine kinase (dtk) activity. the ehv-3 dtk was purified from kyed cytosol dtk by affinity chromatography on deoxythymidine-sepharose and characterized with respect to its electrophoretic mobility, molecular weight, substrate specificity, phosphate donor specificity, and immunological specificity. the purified ehv-3 dtk migrated in polyacrylamide gels with an rf of 0.30 and se ...	1980	7373717
ultrastructure and infectivity of tissues from normal and immunodepressed chickens inoculated with turkey herpesvirus.		1980	7391278
the demonstration of cell-free malignant catarrhal fever herpesvirus in wildebeest nasal secretions.	malignant catarrhal fever (mcf) herpesvirus was isolated from the nasal secretions of 4/11 young wildebeest calves. in two cases virus was demonstrated in filtered secretions. the presence of cell-free mcf virus would suggest that the virus can be transferred from wildebeest to wildebeest and into cattle in nasal secretions.	1980	7451957
selection for virulence and organ-specific metastasis of herpesvirus-transformed lymphoma cells.	the marek's disease virus-transformed, non-producer, lymphoma cell line, mdcc-rpi, was selected by sequential transplantation to produce a highly malignant variant, mdcc-ali. this is evidenced gy an 18-fold decrease in ld50. the new cell line has an increased ability to form metastatic lesions in a distribution which mimics the natural disease. further selections for organ-specific metastasis were undertaken with the isolation of two cell lines, mdcc-al2, selected for liver metastasis, and mdcc- ...	1980	7390658
maternal death secondary to disseminated herpesvirus hominis.		1980	7395942
the detection of the herpesvirus of bovine malignant catarrhal fever in rabbit lymphocytes in vivo and in vitro.	the herpesvirus of bovine malignant catarrhal fever (mcfv, alcelaphine herpes-virus i) causes an acute, fatal lymphoproliferative disorder in rabbits. in dying rabbits, virus antigen and infectivity were associated with medium sized lymphocytes and not with theproliferative lymphoblastoid cells. virus antigen was found diffusely in the cytoplasm and as diffuse or particulate areas in the nucleus of infected cells. fresh suspensions of the lymphoid tissues from rabbits killed 1 to 3 days after th ...	1980	7400778
herpesvirus hominis oesophagitis and oesophageal stricture.	the literature on herpetic involvement of the oesophagus is reviewed and a case is described in which the presumptive clinical diagnosis of primary herpesvirus hominis stomatitis and oesophagitis and subsequently oesophageal strictures was made. the differential diagnosis of an oesophageal lesion and its treatment are discussed.	1980	7404213
isolation of lymphotropic baboon herpesvirus (hvp) from oral swabs of hamadryas baboons of the sukhumi monkey colony.	ways of lymphotropic baboon herpesvirus (hvp) secretion and its excretion into the environment were investigated. oral swabs and feces from the sukhumi main stock hamadryas baboons characterized by a high risk for malignant lymphoma and the baboon stock living in isolation in the forest were used as materials for the investigations. macaque groups of the sukhumi stock were used as controls. it could be shown that the hvp was resistent in the oral cavity of the main stock baboons and was isolated ...	1980	7409079
herpetic arthritis associated with disseminate herpes simplex in a wrestler.	a case of widespread inoculation herpes simplex of the skin is reported in a wrestler. five days after the skin lesions appeared, the right knee became markedly tender and swollen. herpesvirus hominis type i was cultured from the joint exudate as well as from the skin lesions. the determinant of the monoarticular localization of the arthritis appeared to be a prior injury to the knee, rendering it a specific site for deposition of the blood-borne virus.	1980	7426419
long term effects of marek's disease vaccination with cell-free herpesvirus of turkey and age at debeaking on performance and mortality of white leghorns.	three-hundred-sixty, day-old single comb white leghorn chicks were randomly placed in 8 treatment combinations. the combinations consisted of vaccinated or nonvaccinated chicks that were either not debeaked, or debeaked at day-old, 4 weeks old, or 8 weeks old. vaccinated birds received 6,000 plaque forming units of cell-free herpesvirus of turkey vaccine per chick at day-old. debeaking was performed by removing approximately two-thirds of the upper beak. data were analyzed at the 5% level of pro ...	1980	7433359
the pathological features of severe cases of infectious bovine rhinotracheitis.	in recent outbreaks of infectious bovine rhinotracheitis (ibr) in britain a proportion of the animals affected developed a severe clinical disease characterised, at necropsy, by widespread damage to the respiratory tract. they had necrotising rhinitis, pharyngitis, laryngotracheobronchitis with extensive pseudomembrane formation and severe pneumonia with or without interstitial emphysema. renal infarction was seen in approximatley half of the cases. the central nervous system was not affected in ...	1980	7456296
endogenous dissemination of genital herpesvirus hominis type 2 to the eye.	a 33-year-old man developed herpesvirus hominis type 2 (hvh-2) eye disease following a herpetic lesion of the penis. the sequence of ocular involvement suggested that the virus had been transmitted endogenously from the genital lesion: granulomatous iritis was followed by interstitial keratitis and then by dendritic keratitis. recurrent bacterial ulcers ultimately required a conjunctival flap. the course of this man's ocular disease as well as those of other reported cases of hvh-2 adult eye inf ...	1980	7426549
isolation and serological differentiation of a herpesvirus from bobwhite quail (colinus virginianus, l. 1758).	an infectious agent was isolated from the liver of bobwhite quails (colinus virginianus, l. 1758). the agent was sensitive to chloroform and its multiplication was inhibited by 5-iodine-2-deoxy-uridine. it passed filters with a pore diameter of 220 nm and more but not 100 nm filters. electron microscopic examination revealed numerous nucleocapsids with hollow capsomeres and few enveloped particles in the supernatant fluids of infected cultures. the nucleocapsids were calculated to have 162 capso ...	1980	7447711
immune complexes in erythema multiforme and the stevens-johnson syndrome.	early cutaneous lesions of erythema multiforme or mucosal lesions of the stevens-johnson syndrome contain delicate granular deposits of immune reactants and/or complement components lodged in the walls of vessels of the papillary dermis. such deposits are not present in normal, unaffected skin although they can be caused to occur there by injection of substances which increase vascular permeability. factors which cause accumulation of mononuclear cells in the papillary dermis have not been eluci ...	1980	7391609
presence of herpesvirus ovis dna sequences in cellular dna from sheep lungs affected with jaagsiekte (pulmonary adenomatosis).	to investigate further the possible involvement of herpesvirus ovis in the aetiology of jaagsiekte, the kinetics of reassociation of viral dna and dna isolated from tumour tissue as well as from cell cultures derived from it were studied. although dna-dna hybridization could be demonstrated in 2 cases of jaagsiekte, no correlation was found between the presence of herpesvirus ovis genome sequences and the occurrence of the disease.	1980	7413161
severe hearing loss and retinopathy in children: on the possible association with rubella virus infection.	among 145 children with severe hearing loss 35 had a characteristic retinopathy. only few of these had additional malformations. most of these children (28) were born during the months september through february. rubella antibodies were present more frequently than in matched controls. no such difference was found for cytomegalovirus and herpesvirus hominis.	1981	7280544
immunoglobulins, haemolytic complement and serum c3 in cattle infected with malignant catarrhal fever herpesvirus.	serum levels of the third component of complement (c3) were reduced only in the terminal stages in malignant catarrhal fever (mcf) virus-infected steers. haemolytic complement and immunoglobulin (igm, igg1 and igg2) levels were not altered. c3 and immunoglobulin deposits were also not demonstrated in the vascular lesions induced by mcfv. mcf virus infection of cattle is probably not a typical immune complex-mediated disease as previously suggested.	1981	7344271
the histopathologic evolution of recurrent herpes simplex labialis.	in a study of the natural history of recurrent herpes simplex labialis, we examined hematoxylin and eosin-stained sections of biopsies taken from lesions at various clinical stages. the earliest specific findings which could be recognized were changes within the epidermal cell nuclei, including peripheral clumping of chromatin, development of homogeneous "ground glass" appearance, and ballooning of nuclei. eosinophilic intranuclear inclusion bodies were unusual and occurred in late lesions. vacu ...	1981	7298921
[herpesvirus enteritis in kittens].		1981	7302552
inhibition of anatid herpesvirus replication by phosphonoacetate.	phosphonoacetate was found to be an effective inhibitor of the replication and cytopathic effects (cpe) associated with anatid herpesvirus (ahv) infections in avian cells. in low multiplicity of infection (moi) (10(-3) or less) infected pekin duck and chicken fibroblast cultures, the dosage required for a 50% plaque reduction was approximately 20 microgram/ml. the amount of the inhibitor needed for complete prevention of cpe was found to be moi dependent with up to 190 microgram/ml required at a ...	1981	7296412
induction of target antigens and conversion to susceptible phenotype of nk-cell-resistant lymphoid cell line.	two autologous herpesvirus papio producer lymphoid cell lines and one autologous non-producer line were compared for susceptibility to natural killer (nk) cell-mediated lysis. the non-producer cell line, 26cb-1, was more resistant to nk cell killing compared to one viral producer counterpart 13cb-1, but equally resistant when compared to another, 8cb-1. treatment with chemical agents that affect differentiation or activate the viral cycle, including n-butyrate, iudr, 5-azacytidine and tunicamyci ...	1981	7309297
effect of diluent volumes on the serological efficacy of intranasal bovine herpesvirus 1 strain rlb 106 ts in controlling infectious bovine rhinotracheitis.		1981	7340086
herpesviridae. definition, provisional nomenclature, and taxonomy. the herpesvirus study group, the international committee on taxonomy of viruses.		1981	7343541
herpesvirus neutralising antibody in grey kangaroos.		1981	7340790
herpesvirus in infertile bull's testicle.		1981	7257133
reduced vaccinal protection of turkey herpesvirus against field strains of marek's disease herpesvirus.	four isolates of marek's disease herpesvirus (mdv) were obtained from 21-week-old broiler breeders with lesions and mortality from marek's disease (md). they had been properly vaccinated with turkey herpesvirus (hvt). the isolates were designated ala-7, 8, 9, and 10. these 4 mdv strains were compared with the ga isolate of mdv in chickens vaccinated with graded doses of hvt. challenge with the mdv strains was also with graded doses. all 5 isolates of mdv were similar in virulence. however, prote ...	1981	7267529
herpesvirus type 2 in adenocarcinoma of the uterine cervix: a possible association.	sera from 16 jewish patients with histologically confirmed adenocarcinoma of the uterine cervix (auc) and 32 control subjects matched by age and ethnic origin were examined for herpesvirus type 1 (hsv-1) and type 2 (hsv-2) neutralizing antibodies. titers were determined by means of the quantitative plaque reduction neutralization test on vero cell monolayers, using hsv-1 strain vr3 and hsv-2 strain. significantly increased levels of antibodies against both virus strains were found in the auc pat ...	1981	7284955
herpesvirus hominis hepatitis of mother and newborn infant.		1981	7268504
failure of a subunit bovine herpesvirus 1 vaccine to protect against experimental respiratory disease in calves.	in two experiments in which 31 calves were used, a bovine herpesvirus 1 subunit vaccine previously shown to elicit a strong immunological response in adult cattle failed to do so in younger animals and failed to protect against pneumonia caused by sequential exposure to virulent bovine herpesvirus 1 and pasteurella haemolytica aerosols. one of the experimental groups had been previously inoculated with a live commercial vaccine but even this failed to elicit a strong immunological response. thes ...	1981	7272846
comparison of constant and variable virus methods of measuring virus neutralizing antibodies to bovine herpesvirus.		1981	7275995
marek's disease: a natural model for the landry-guillain-barré syndrome.	the early lesions of marek's disease in chickens are indistinguishable from those of the landry-guillain-barré syndrome in human beings. because of these similarities, and since the etiological agent (a herpesvirus) is known, marek's disease can be meaningfully exploited as a model of the landry-guillain-barré syndrome. recent work in our laboratories has shown that the agent establishes latent infections in neuronal supporting cells and that affected birds mount cellular and humoral immunologic ...	1981	7224611
multicystic encephalomalacia due to fetal viral encephalitis.	two children, aged 2 weeks and 2 months, with multicystic encephalomalacia aer described. although computerized tomography (ct) scan was used for the diagnosis, the value of the simple method of transillumination is stressed. the mother of one child had mumps with meningitis at 26 weeks' gestation. the other child had an echovirus 11 isolated from the cerebrospinal fluid and herpesvirus hominis (hvh) from the skin at 8 weeks. we speculate that the changes in the brains of these babies may be due ...	1981	7196836
neutralising antibodies to malignant catarrhal fever herpesvirus in wildebeest nasal secretions.		1981	7196099
the development of delayed cutaneous hypersensitivity in rabbits infected with the herpesvirus of malignant catarrhal fever.		1981	7197205
isolation and characterization of a herpesvirus from topi (damaliscus korrigum, ogilby).		1981	7343576
visualization of minute centers of viral infection in unfixed cell cultures by an enzyme-linked antibody assay.	enzyme-linked antibody was used to treat unfixed herpesvirus-infected human fetal lung cell cultures in a mode which permitted the visualizing of local sites of infection. foci containing as few as 20 herpesvirus-infected cells produced sufficient viral mass to be easily detectable by this method. 'clouds' or 'plumes' of colored reaction product diffused into the substrate overlay, accumulated above and around each focus of infection and allowed quantitation of the number of foci in a culture. t ...	1981	7019340
bioassay system for determining ribavirin levels in human serum and urine.	a simple, sensitive, micromethod was developed to determine levels of ribavirin, or its active metabolic products, in human serum or urine. the procedure utilized the inhibition of measles virus cytopathic effect in bs-c-1 cells. based upon maximum dilutions of human serum or urine containing ribavirin which inhibited the measles virus, the bioassay detected ribavirin in concentrations as low as 0.006 microgram/ml in serum or 0.03 microgram/ml in urine. herpesvirus 1, parainfluenza virus 3 and r ...	1981	7011693
viruses and gynecologic cancers: herpesvirus protein (icp 10/ag-4), a cervical tumor antigen that fulfills the criteria for a marker of carcinogenicity.	the studies associating infections by herpes simplex virus type 2 (hsv-2) with carcinoma of the human uterine cervix are reviewed within the context of three possible interpretations. extensive seroepidemiologic evidence indicates that the virus does not grow preferentially in neoplastic tissue, nor is the association of hsv-2 with cervical carcinoma a reflection of their independent relationship to promiscuity. while a number of infectious agents, including other viruses, are associated with ce ...	1981	7023662
adult t-cell leukemia: antigen in an atl cell line and detection of antibodies to the antigen in human sera.	indirect immunofluorescence of certain human sera demonstrated an antigen(s) in the cytoplasm of 1--5% of the cells of a t-cell line, mt-1, from a patient with adult t-cell leukemia (atl), which is endemic in southwestern japan. the antigen was not detected in other human lymphoid cell lines, including six t-cell lines, seven b-cell lines, and four non-t non-b cell lines. the antigen did not show cross antigenicity with that of herpesviruses, including epstein--barr virus, herpes simplex virus, ...	1981	7031654
primary disseminated herpes simplex infection with fulminant hepatitis following renal transplantation.	a patient had disseminated herpes simplex, type 1, virus infection manifested by fulminant hepatitis and disseminated intravascular coagulation. the diagnosis was established by isolation of the virus from throat, urine, and buffy coat and confirmed at autopsy by the visualization of typical inclusions, demonstration of herpesvirus particles by electron microscopy, and specific immunoperoxidase staining. therapy with vidarabine did not alter the fatal course. on the basis of clinical features an ...	1981	7025779
three years' experience of sexually transmitted diseases in seville, spain.	at present there are no reliable statistics on the relative prevalences of sexually transmitted diseases (stds) in spain. in a report of the first three years' experience in an std diagnostic centre between 1977 and 1979 a total of 879 patients (534 men adn 345 women) were seen. they mainly consisted of university students and the mean age was 22 years in 1977 and 23 years in the following two years. all the patients were examined for syphilis and all women for gonorrhoea and trichomoniasis. inv ...	1981	6894560
cytologic evidence of the association of condylomatous lesions with dysplastic and neoplastic changes in the uterine cervix.	cytologic smears were obtained from 272 women shown, during a mass screening program, to have histologically proven severe dysplasia, carcinoma in situ or invasive squamous cell carcinoma of the uterine cervix. these smears were scrutinized with special attention to the detection of the cytologic pattern recently established as diagnostic of condyloma virus infection in the genital tract. the results disclosed positive cytologic findings in a considerable percentage of the smears studied, in con ...	1981	6937062
relationship between herpesvirus ateles-associated nuclear antigen (hatna) and the number of virus genome equivalents in hva-carrying lymphoid lines.	a dna-binding antigen (hatna) was demonstrated in 7 out of 14 cell lines carrying herpesvirus ateles (hva) by the acid-fixed nuclear-binding technique. the seven hatna-positive lines had means of 95, 96, 103, 177, 240, 343 and 326 virus genome equivalents/cell. for the seven hatna-negative lines, the figures were 4, 8, 10, 33, 39, 72 and 110. this indicates a relationship between the number of hva genome equivalents/cell and the detectability of hatna. this association was independent of the vir ...	1981	6793691
a marmoset t lymphoma which functions as a human amplifier t cell.	a long-term in vitro grown t cell line derived from a cotton-topped marmoset (saguinus oedipus) infected with herpesvirus saimiri was fond to share surface antigens with human amplifier t cells and to augment the capacity of human b cells to secrete immunoglobulin. this is the first demonstration of t/b collaboration across such a large phylogenetic barrier and might have interesting implications for understanding the nature of molecular interactions mediating cell/cell cooperation.	1981	6801144