Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| identification of a cell-associated morbillivirus from cattle affected with malignant catarrhal fever: antigenic differentiation and cytologic characterization. | 1979 | 230764 | |
| enhancement of fluorescent antibody staining of viral antigens in formalin-fixed tissues by trypsin digestion. | the staining of viral antigens present in formalin-fixed, paraffin-embedded tissues by fluorescent antibodies is markedly enhanced by trypsin digestion. when the trypsin digestion method was used to detect viral antigens present in hamster brain following experimental infection with measles virus, the results were comparable to those obtained with acetone-fixed, freshly frozen tissues that had been sectioned with a cryostat. measles antigens were readily identified in brain cells from a patient ... | 1979 | 231070 |
| [demonstration by immunofluorescence and immunoperoxidase of an antigen of the measles type in the osteoclasts of paget's disease of bone]. | the intra nuclear and intra cytoplasmic inclusions described in osteoclasts in paget's bone disease are morphologically similar to those observed in subacute sclerosing panencephalitis. immunological techniques using different specific immune sera demonstrate the presence of an antigenic structure of viral origin in osteoclasts in paget's bone disease. a measles or a measles like virus is most likely to be involved and may play a role in the etiology of the disease. | 1979 | 233348 |
| [measles]. | 1979 | 256636 | |
| [effectiveness of measles inoculations in the hungarian people's republic]. | 1979 | 262709 | |
| [serological study of postvaccinal measles immunity in the absence of a booster effect and in measles foci]. | 1979 | 262711 | |
| [development of an associated measles and mumps preparation]. | 1979 | 262712 | |
| [experience with the large-scale manufacture of a live associated mumps-measles vaccine]. | 1979 | 262713 | |
| measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the m protein in patients with subacute sclerosing panencephalitis. | studies on the immunoprecipitation of the proteins of several different measles and subacute sclerosing panencephalitis (sspe) virus strains from lysates of infected cells have revealed a relative lack of antibodies to the nonglycosylated viral membrane protein (m) in the sera of patients with sspe, in contrast to a high level of antibodies to other viral proteins. no evidence was found for the existence of a large number of antigenically unique m proteins. in contrast to sspe sera, other hyperi ... | 1979 | 287042 |
| giant-cell pneumonia and lung tumorlets in a leukemic four-year-old child. | the authors report a case of a 4-year-old child whose death resulted from acute lymphoblastic leukemia (all) and giant-cell pneumonia. typical lung tumorlets were occasionally observed. on electron microscopy study it was possible to demonstrate a large number of neurosecretory granules in the tumorlet's cells, identical to those present in kulchitsky's cells. these studies suggest the occurrence of an abnormal immunitary process. | 1979 | 291224 |
| antigenic relationships between measles and canine distemper viruses: comparison of immune response in animals and humans to individual virus-specific polypeptides. | precipitation with hyperimmune rabbit sera, sera from patients convalescing from measles, and sera from patients with subacute sclerosing panencephalitis, followed by electrophoresis, enabled antigenic relationships between the individual polypeptides of measles and canine distemper viruses to be examined. virus isolates from patients with acute measles or subacute sclerosing panencephalitis showed no antigenic differences. with rabbit hyperimmune sera, antigenic crossreactivity was present betw ... | 1979 | 293747 |
| [measles--giant cell pneumonia]. | 1979 | 423752 | |
| influence of moderate malnutrition on morbidity and antibody response following vaccination with live, attenuated measles virus vaccine. | 1979 | 427297 | |
| a comparison of polypeptides in measles and sspe virus strains. | the polypeptide patterns of twelve subacute sclerosing panencephalitis (sspe) and measles viruses have been compared by slab gel electrophoresis. the polypeptide patterns of nine strains of sspe and measles virus were identical. differences in the np protein and the ha protein of the oddo strain, the p protein of the large plaque variant of the lec strain of sspe and in the m protein of the hu 2 measles strain could not be correlated with biological characteristics such as plaque morphology, ori ... | 1979 | 430032 |
| postvaccine era measles epidemiology. | measles incidence in the united states was calculated from estimates of the united states immunization survey for the years 1965 to 1975. these data were examined according to birth cohorts and cross-sectionally by age to determine the effect of live measles virus vaccine on measles epidemiology. the results showed a high rate of infection for children aged 1 year, followed by a decrease in the infection rates for preschool children, with rates increasing agin at ages 5 and 6 years. it was hypot ... | 1979 | 430684 |
| igg synthesis within the brain in multiple sclerosis and subacute sclerosing panencephalitis. | intracerebral igg synthesis was measured in patients with multiple sclerosis (ms), subacute sclerosing panencephalitis (sspe) and in two control groups--patients with other neurological disorders and patients with non-neurological diseases. significantly increased synthesis was found at all times in sspe (p less than 0.001). significantly elevated values were also found in ms (p less than 0.001), but in this group increased values were found mainly during relapse. these findings emphasize the im ... | 1979 | 436336 |
| neutralizing antibodies to canine distemper and measles virus in multiple sclerosis. | serum neutralizing antibody to canine distemper virus (cdv) was measured in 142 patients with multiple sclerosis (ms), an equal number of age and sex-matched normal controls, and 75 patients with other neurological disorders. an elevated antibody titer was found in the ms population compared to controls. measles-neutralizing antibody was also found to be elevated in 128 patients with ms. the mean ratio of measles to cdv antibody was similar in the control and ms groups, but a wide range of measl ... | 1979 | 438844 |
| pneumonia of atypical measles. | infection with rubeola virus after previous immunization with killed measles virus vaccine produced abnormal chest radiographs in 9 patients. variable pneumonic consolidation occurred in all cases and was mainly lobar or segmental in distribution. four patients had hilar adenopathy, 3 pleural effusion, and in 1 instance a pulmonary nodule remained 9 months after clearing of the acute pneumonia. atypical measles pneumonia is a presumed hypersensitivity response in incompletely immunized patients. | 1979 | 441371 |
| contributions to the diagnosis of subacute sclerosing panencephalitis in children. | 1979 | 441662 | |
| temperature-dependent expression of measles virus structural proteins in persistently infected cells. | 1979 | 442534 | |
| epidemic measles in young adults. clinical, epidemiologic, and serologic studies. | an outbreak of measles at the university of california at los angeles provided the opportunity to study clinical, epidemiologic, and serologic characteristics of the disease in young adults in the present vaccine era. of the 34 cases studied, 18 occurred in persons who thought they were immune. fifteen of 19 seronegative students vaccinated during the epidemic responded with a secondary (igg) antibody response. antibody prevalence studies indicated that 91% of the student population had measles ... | 1979 | 443682 |
| atypical measles in adolescents and young adults. | seven patients, aged 12 to 19 years, had atypical measles. prodromal symptoms of fever, malaise, myalgia, headache, nausea, and vomiting were commonly followed by coryza, sore throat, conjunctivitis, photophobia, nonproductive cough, and pleuritic pain. the characteristic rash was erythematous, maculopapular, and progressed frequently to vesicular, petechial, or purpuric lesions. it initially involved palms and soles with subsequent spread to proximal extremities and the trunk, sparing the face. ... | 1979 | 443683 |
| measles and rubella virus antibodies in patients with multiple sclerosis. a longitudinal study of serum and csf specimens by radioimmunoassay. | a longitudinal study on rubella, measles, and respiratory syncytial virus antibodies in serial serum and csf specimens from 20 multiple sclerosis (ms) patients was performed, using solid-phase radioimmunoassay. albumin and immunoglobulin g (igg) levels were also measured to check the integrity of the blood-brain barrier and the intrathecal igg production. all the patients had local igg production in their cna. a local antibody production against one or more of the viruses studied was evident in ... | 1979 | 444095 |
| subacute sclerosing panencephalitis during pregnancy. a surviving normal infant. | a normal infant was born to a 15-year-old girl who developed subacute sclerosing panencephalitis in the fifth month of pregnancy. the serum measles antibody titers of the infant gradually declined during the first year of life. the child, now age 3, has no neurological abnormalities. | 1979 | 444101 |
| potentiation of experimental allergic encephalomyelitis in hamsters with persistent encephalitis due to measles virus. | to clarify mechanisms underlying acute disseminated encephalomyelitis (ade) in patients with infection due to measles or other viruses, a new animal model was devised. adult hamsters that had clinically recovered from acute encephalitis induced by prior intracerebral injection of the hbs strain of measles virus were challenged with neuroantigen plus adjuvant. such hamsters, which had a high likelihood of carrying persistent hbs measles virus in the central nervous system (cns), exhibited a signi ... | 1979 | 448185 |
| additional evidence against measles vaccine administration to infants less than 12 months of age: altered immune response following active/passive immunization. | quantitative serologic responses following the inoculation of infants less than one year of age with live, further-attenuated measles virus vaccine were compared to those of infants and children inoculated after one year of age. active/passive immunization resulted in reduced antibody formation in some infants especially those less than 9 months of age. thirty-seven infants identified as "vaccine failures" following their initial inoculation at less than one year of age were revaccinated after o ... | 1979 | 448525 |
| characterization of measles virus-specific proteins synthesized in vivo and in vitro from acutely and persistently infected cells. | measles virus protein synthesis has been analyzed in acutely and persistently infected cells. to assess the role of measles in subacute sclerosing panencephalitis (sspe), measles viral proteins synthesized in vivo or in vitro were tested for reactivity with serum from a guinea pig(s) immunized with measles virus and sera from patients with sspe. guinea pig antimeasles virus serum immunoprecipitates the viral polypeptides of 78,000 molecular weight (glycosylated [g]), 70,000 molecular weight (pho ... | 1979 | 448796 |
| antiviral antibody reacting on the plasma membrane alters measles virus expression inside the cell. | 1979 | 450095 | |
| viral pathogenesis and virulence. | 1979 | 450136 | |
| alterations of the thymus and peripheral lymphoid tissues in fatal measles. a review of 14 autopsy cases. | as a result of re-examining 14 autopsy cases of fatal measles, neither aplastic nor hypoplastic thymuses were found even in a case with giant cell pneumonia, but there were degenerative and/or necrotic changes with giant cells mostly in the thymus and less in the peripheral lymphoid organs such as spleen, lymph nodes, peyer's patches and tonsils. this damage of the lymphoid system was associated with the occurrence of complications, particularly of giant cell pneumonia and encephalitis. the lymp ... | 1979 | 452905 |
| serological survey of measles virus infection in children in pondicherry area. | 1979 | 457205 | |
| variable infection of vero cells and homologous interference after co-cultivation with hela cells with persistent defective infection by edmonston measles virus. | the hela subline k11a-hg-1 (line of hela cells persistently infected with edomonston measles virus but containing little or no transmissible infectious virus) was co-cultivated with vero cells. focal syncytia were formed containing measles antigen and accumulations of nucleocapsid-like structures with no detectable production of transmissible infectious virus or positive hemadsorption. the infection aborted between 2 and 3 weeks after preparation of co-cultures. upon subculture of co-cultures, o ... | 1979 | 457258 |
| immunoglobulin g from subacute sclerosing panencephalitis brain as an immunological reagent. | proteins were extracted at ph 2.5 from carefully washed brain homogenates of patients with subacute sclerosing panencephalitis. immunoglobulin g was isolated from the extracts by gel filtration and immunoadsorbent chromatography and was 125i radioiodinated. the labeled immunoglobulin g was reacted with purified measles virus antigens by crossed immunoelectrophoresis and utilized to identify antigens in measles-infected cell cultures and hamster brain tissue subjected to treatment corresponding t ... | 1979 | 457270 |
| classification of peste des petits ruminants virus as the fourth member of the genus morbillivirus. | peste des petits ruminants (ppr) is a virus disease of sheep and goats in west africa. when first described, the virus was considered a variant of rinderpest virus. the biological and physicochemical characteristics of the virus indicate that it is closely related to measles, rinderpest and canine distemper viruses. these three viruses form the genus morbillivirus of the paramyxoviridae. ppr virus is sufficiently distinct from these 3 viruses to justify considering it as the fourth member of the ... | 1979 | 457363 |
| a study of the measles virus-induced proteins incorporated into the cell membrane. | the polypeptide composition of a measles virus isolate from a case of subacute sclerosing panencephalitis, the halle strain, and the distribution of these polypeptides in the cell membrane have been investigated. in purified virus preparations, four major polypeptides were identified with molecular weights corresponding to 80k, 62k, 42k and 37k daltons. a minor band was found at 69k and several others with molecular weights +/- 100k. by specifically labeling the proteins exposed at the surface o ... | 1979 | 457364 |
| multiple sclerosis: etiology and epidemiology. | multiple sclerosis (ms) is a demyelinating, auto-immune disease which affect the central nervous system. the research seems to implicate a small or incomplete slow-growing virus as the causative agent. the measles virus has been suspected because of high titers of measles antibodies in ms patients' serum and cerebrospinal fluid. an immunological deficiency in ms patients may be linked to genetic factors such as hl-a tissue types and histocompatibility antigens. genetics and socioeconomic conditi ... | 1979 | 458098 |
| immune response in subacute sclerosing panencephalitis: reduced antibody response to the matrix protein of measles virus. | immune precipitation was used to study the humoral immune response of patients with subacute sclerosing panencephalitis (sspe). patients with sspe have a progressive infection of the cns by measles or a measles variant despite high serum antibody levels to measles virus as measured by standard serologic techniques. however, when the antibody response to individual measles virus proteins was measured, we found a striking reduction in the ability of sera from patients with sspe to precipitate the ... | 1979 | 458157 |
| temperature sensitivity of subacute sclerosing panencephalitis virus and its ability to establish persistent infection. | 1979 | 461471 | |
| measles virus specific precipitins in sera from patients with chronic active hepatitis. | measles virus specific antibodies in sera from 29 patients with chronic active hepatitis have been examined using standard serological tests and immunoelectrophoretic techniques. significantly raised cf antibody titres against measles virus antigen were demonstrated in 50% of the sera. the major immunoprecipitate obtained by immunoelectrophoresis was shown to contain aggregates of measles virus nucleocapsids. antibodies against the haemagglutinin antigen of the virus envelope were also raised an ... | 1979 | 462137 |
| late-onset malignant astrocytoma in a case of multiple sclerosis. clinical, neuropathological, virological, and tissue culture studies. | an unusual case of concurrent ms and anaplastic astrocytoma is presented. ms was diagnosed in a female patient at the age of 22 years. a left side thalamotomy was performed for relief of severe intention tremor at age 28 and at age 32 she received immunosuppressive therapy for 1 year. at the age of 36 after a severe exacerbation of her symptoms a left side fronto-temporal tumor was diagnosed and a subtotal neurosurgical extirpation was performed. histopathologically, the tumor was an anaplastic ... | 1979 | 463500 |
| enhancement and suppression by actinomycin d of a vero cell nontransmissible measles infection. | the effect of low doses of actinomycin d on vero cell nontransmissible measles infection produced after cocultivation with a hela subline with persistent defective infection by edmonston measles virus was examined by pretreatment of vero cells with the drug and treatment at 1, 4, and 7 days after vero cell infection. pretreatment enhanced focal formation of viral immunofluorescent vero cell syncytia but did not induce synthesis of detectable amounts od cocultures suppressed syncytial formation, ... | 1979 | 468384 |
| [etiological factors and disturbances of local immunity as the origin of recurrent respiratory infections. role of viruses]. | 1979 | 471764 | |
| demonstration of anti-rubella antibody-secreting cells in rheumatoid arthritis patients. | in the present study we describe a plaque-forming cell assay using erythrocytes coated with viral antigen, which detected anti-viral antibody-secreting cells against various viral antigens. these anti-viral antibody-secreting cell were studied in normal individuals with known viral infections and in rheumatoid arthritis patients. rubella anti-viral antibody-secreting cells were present after induction in the peripheral blood of eight out of ten patients. no plaques were seen before induction. sy ... | 1979 | 472665 |
| lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibody. | the dependence of antibody-and-complement-mediated lysis of virus-infected cells on the alternative pathway was examined utilizing the isolated cytolytic alternative pathway--a system consisting of the six purified proteins of the alternative pathway of activation (c3, factors b and d, beta 1h, c3b inactivator and properdin), and the five proteins of the membrane attack pathway (c5--9) of complement. hela cells acutely infected with measles virus were lysed by anti-viral igg and the isolated cyt ... | 1979 | 479760 |
| role of virus variants and cells in maintenance of persistent infection by measles virus. | hamster embryo fibroblasts persistently infected with a derivative of the schwarz vaccine strain of measles virus spontaneously released virus particles with an average buoyant density considerably lower than that of the parental virus. the released virus contained all of the measles virus structural proteins and interfered with replication of standard virus. all of the virus structural proteins were associated with a membrane-free cytoplasmic extract from the persistently infected cells. membra ... | 1979 | 480462 |
| the binding of protein a of immunoglobulin g and of fab and fc fragments. | results are presented to show that protein a (pa) may fix to the fab region of igg outside the antigen binding site. thus, pa-reactive fab fragments were isolated both from specific anti-egg albumin and specific anti-measles virus antibodies. a probable significance of this fab reactivity in the precipitation reaction between igg and pa is discussed. reactive igg from human, guinea pig, rabbit, and porcine normal sera all showed similar avidity towards pa. slight differences between igg subclass ... | 1979 | 484238 |
| lymphocyte-mediated cytotoxicity to measles virus in patients with multiple sclerosis. | 1979 | 487666 | |
| measles virus-specific igm antibodies and igm-class rheumatoid factor in serum and cerebrospinal fluid of subacute sclerosing panencephalitis patients. | 1979 | 487667 | |
| alternative complement pathway-mediated lysis of measles virus infected cells: induction by igg antibody bound to individual viral glycoproteins and comparative efficacy of f(ab')2 and fab' fragments. | 1979 | 489977 | |
| isolation and characterisation of a defective measles virus from a subacute sclerosing panencephalitis patient. | a cytopathic measles virus was isolated from a brain biopsy of a subacute sclerosing panencephalitis (sspe) patient. the agent could be transferred to vero cells by cocultivation, but the infectivity always remained cell-associated -ie, a defective virus infection. the cell-associated nature of the virus was retained through 25 passages in vero cells. intracerebral inoculation of hamsters (2-6 days old) with the cocultured vero cells gave rise to 100% mortality in 5-7 days. the virus retained it ... | 1979 | 490144 |
| hla antigens and the response to influenza a virus. | an attempt was made to confirm a previously reported association between hla type b16 and resistance to infection with live attenuated influenza a virus vaccine. no differences were found either in the ability of influenza virus to attach to fractionated white blood cells from hlb b16 subjects compared to cells from subjects of other hla types, nor in the incidence of antibodies to three consecutive epidemic strains of influenza in sera from b16 subjects and control subjects. the association bet ... | 1979 | 494590 |
| antibodies to the acetylcholine receptor in myasthenic dogs. | antibodies to the achr and anti-striational antibodies have been detected in dogs suffering from myasthenia gravis. the detection of these antibodies adds to the known similarities between the human and canine disease. this animal model will facilitate investigation of agents involved in the induction of spontaneous myasthenia gravis. | 1979 | 500127 |
| cytotoxic antibody to cells infected with measles virus in serum and cerebrospinal fluid of multiple sclerosis and control patients. | sera and cerebrospinal fluids (csfs) from 66 patients selected from a larger sample of multiple sclerosis (ms) and control patients were studied for presence of complement-dependent cytotoxic (ct) antibody against baby hamster kidney cells infected with measles virus, strain lec. the ms group contained 26 patients with clinically definite disease and 7 with probable ms. seventeen of the 33 patients selected from the ms group had hemagglutination-inhibiting (hi) antibody to measles virus in their ... | 1979 | 500802 |
| effect of undiluted passage on the polypeptides of measles virus. | measles virus induces a large polypeptide (l; mol. wt. 180 k), a large glycopolypeptide (h; mol. wt. 80 k), a nucleocapsid associated polypeptide (p; mol. wt. 70 k), a nucleocapsid polypeptide (n; mol. wt. 60 k), a second glycopolypeptide (f0; mol. wt. 60 k), a matrix or membrane polypeptide (m; mol. wt. 37 k) and a small polypeptide (s; mol. wt. 15 k). the second glycopolypeptide (f0) appears to be cleaved in purified measles virus. defective interfering particles accumulate during passage of m ... | 1979 | 501334 |
| cell-free synthesis of measles virus proteins. | polyadenylated mrna extracted from cytoplasm of measles virus-infected vero cells was translated in a cell-free system. three of the polypeptides obtained corresponded to nucleocapsid protein, phosphoprotein, and membrane protein of measles virions. a fourth polypeptide, present in measles virus-infected cells, could be generated by addition of vero cytoplasmic extract and was identified as a cleavage product of the nucleocapsid protein. | 1979 | 501804 |
| [effect in vitro passages on biological properties of attenuated strains of measles virus. ii. immunogenic activity]. | 1979 | 502644 | |
| [chronic measles neuroinfection in syrian hamsters]. | measles neuroinfection was studied in 3-week syrian hamsters inoculated intracerebrally with the neurovirulent edmonston-42 strain of measles virus. the infectious virus was shown to be recoverable from the animals' brains both early after infection (up to 16 days) and at later intervals (28--63 days). at the same intervals (up to 69 days), measles antigen was demonstrated in brain impressions. all the animals under study had rna-containing inclusions in some cells, slight cellular infiltrates a ... | 1979 | 506206 |
| subacute sclerosing panencephalitis after drug-induced immunosuppression. | a girl developed subacute sclerosing panencephalitis (sspe). eight years earlier she had had measles infection contracted shortly after cytotoxic treatment and radiotherapy for a spinal neuroblastoma. the case illustrates that typical sspe, like immunosuppressive measles encephalopathy, can arise after drug-induced immunosuppression, and supports the view that these diseases probably represent opposite ends of a spectrum induced by measles virus infection in an individual with some form of immun ... | 1979 | 507919 |
| [experimental model for studies on viral encephalitis (author's transl)]. | 1979 | 507949 | |
| measles virus-specified polypeptide synthesis in two persistently infected hela cell lines. | measles virus-directed protein synthesis was examined in two hela cell lines (k11 and k11a) that are persistently infected with wild-type measles virus. four viral proteins (h, hemagglutination protein; p, nucleocapsid-associated protein; np, the major nucleocapsid protein; and m, the matrix protein) were readily detected in both cell lines by immune precipitation of [(35)s]methionine-labeled cell extracts followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. when analyzed by so ... | 1979 | 513191 |
| efficient propagation of measles virus in suspension cultures. | suspension cultures of a human prostate cell line (ma160) supported abundant growth of the edmonston strain of measles virus. the virus yields obtained with these suspension cultures (150 to 800 pfu/cell) were at least 20- to 100-fold higher than those frequently reported in the literature. monolayer cultures of ma160 cells did not support a virus replication nearly as efficiently (progeny yield, 25 pfu/cell). | 1979 | 513197 |
| follow-up surveillance for antibody in human subjects following live attenuated measles, mumps, and rubella virus vaccines. | 1979 | 515009 | |
| evidence for lack of synthesis of the m polypeptide of measles virus in brain cells in subacute sclerosing panencephalitis. | 1979 | 516455 | |
| growth of measles virus in continuous cell lines derived from the nervous tissues of human and rat. | growth of two measles virus strains, the tycsa and cam, was compared in three continuous cell lines derived from the nervous tissues, human neuroblastoma imr-32, human glioma 118mgc, and rat glioma c-6. the two human neural cells were shown to support the growth of both measles virus strains as efficiently as in the non-neural vero cells. different types of cytopathic effect (cpe) between the two virus strains were noticed in imr-32 cells; the cam strain induced strand-forming type cpe and the t ... | 1979 | 518297 |
| measles sero-immunity in rural non-vaccinated children of busoga district, uganda. | 1979 | 520246 | |
| neurological complications following measles vaccination. | in hamburg 18 cases of neurological complications following vaccination with live measles virus vaccine (including 2 cases of abortive encephalopathy) have been observed between 1971--1978. a causal connection was assumed in 14 cases, that means an incidence of 1 neurological complication per 2,500 vaccinees and an incidence of 1 abortive encephalopathy per 17,650 vaccinees. these results differ from studies of various countries which used the same vaccine strain (schwarz). clinical symptoms, ag ... | 1979 | 520673 |
| measles antibodies and histocompatibility types in multiple sclerosis. | measles antibody titres and hla antigens were determined in 71 white and 11 coloured multiple sclerosis (ms) patients and 71 white and 11 coloured age and sex-matched controls. measles antibody titres were determined by the hemagglutination inhibition test and hla antigens were determined serologically by a micro-lymphocytotoxicity test. measles antibody titres were significantly higher in ms than in control cases and this was true for both female and male patients. no association was observed b ... | 1979 | 521827 |
| modulation of the adherence of human lymphocytes to measles-infected cells by prostaglandin e1: a differential effect on lymphocyte subpopulations. | prostaglandins of the e series (pge) may serve as important regulators of human immune responsiveness. the present study was designed to examine the possibility that pge may effect human lymphocyte function by the modulation of surface receptors. the presence of surface binding sites on human lymphocytes for measles virus antigens was studied using a rosette adherence assay. we observed that the addition of pge1 increased the proportion of measles-infected cells (hela-kll) with adherent lymphocy ... | 1979 | 523674 |
| assay of interferon and viral antibodies in the cerebrospinal fluid in clinical neurology and psychiatry. | cerebrospinal fluids (csf) of 245 neurological and 194 psychiatric patients were tested for viral antibodies and interferon. complement dependent neutralizing antibodies to herpesvirus hominis 1 were found in the csf of patients with encephalitis (50.6%), meningitis (35.4%), lesions of peripheral nerves (36.9%), sclerosis multiplex (41.2%), schizophrenia (31.9%), senile dementia (51.4%), mental retardation (11.1%), ethylism (43.5%). neutralizing antibodies to tick-borne encephalitis virus were f ... | 1979 | 525159 |
| [psoriasis and measles (author's transl)]. | 1979 | 527060 | |
| sspe-biken: a naturally arising hemagglutination-defective mutant of measles virus. | biochemical and genetic methods have been used to investigate a defective variant of measles virus previously isolated from a patient with subacute sclerosing panencephalitis (sspe). since its isolation, this syncytiogenic strain (sspe-biken) has remained cell-associated; infected cells do not hemadsorb and do not release infectious virus. immune precipitation and polyacrylamide gel electrophoresis were used to study the synthesis of measles virion proteins in sspe-biken-infected cells. all of t ... | 1979 | 528985 |
| the usefulness of measles haemagglutination inhibition test in detecting rinderpest antibodies in cattle and sheep after inoculation of tissue culture rinderpest vaccine. | 1979 | 536029 | |
| [subacute sclerosing panencephalitis. a case with a prolonged course in an adult. isolation and characteristics of a "defective" measles virus (author's transl)]. | a 33-year-old man had a 6-year history of clinical signs suggesting multiple sclerosis : visual lesion at 27 years of age, cerebellar and visual disturbances at 31, which partly regressed, lymphocytosis and increased-gammaglobulin levels in the cerebrospinal fluid. biological and anatomical (optical and ultrastructural) examinations gave results typical of a subacute sclerosing panencephalitis. a cytopathogenic measles virus was isolated from a cerebral biopsy specimen. the agent was transmissab ... | 1979 | 538383 |
| subacute sclerosing panencephalitis in chandigarh. | 1979 | 541000 | |
| detection of igg antibody to measles virus by radioimmunoassay technique. | a highly sensitive procedure of solid-phase radioimmunoassay (ria) was developed for the detection of measles igg antibody. hela cells persistently infected with measles virus were used as a solid-phase antigen. this technique was applied to the detection of measles igg antibody in patients with subacute sclerosing panencephalitis (sspe) and multiple sclerosis. normal subjects having experienced natural measles or measles vaccination and patients with various neurological diseases of non-virus n ... | 1979 | 541873 |
| the accelerated storage test applied in the study of thermal stability of haemagglutinating measles virus antigen. | 1979 | 546374 | |
| [multiple sclerosis: immunological aspects in relation with the measles virus]. | 1979 | 550223 | |
| [the actual aspects of measles vaccinations (author's transl)]. | following a brief introduction to measles epidemiological aspects and complications, the authors expound on the essential characteristics of various types of vaccinations. they then synthesize the effects, indications, contraindications and duration of the immunization in relation to measles vaccinations. | 1979 | 554554 |
| the present prophylactic trends of rubella and measles. | starting from the epidemiological investigation on a sample of 22.560 subjects of different chronological age classes in the latium region with the research of hemoagglutinoinhibiting antibodies of the rubella virus, and of 9.800 subjects with the research of hemoagglutinoinhibiting antibodies of the measles virus, the authors observe that the diffusion of the seroprotection presents on an average 82.5% for rubella and 79.8% for measles. on the strength of the results, referred also according to ... | 1979 | 555675 |
| antibodies against latent neurotropic viruses in serum and cerebrospinal fluid samples from patients with multiple sclerosis. | 1979 | 556120 | |
| [neurological complications following measles virus vaccination. evaluation of the cases seen between 1971--1977 (author's transl)]. | within 11 days following vaccination with live virus vaccine in hamburg 18 cases of neurological complications have been observed between 1971--1977, including 2 cases of abortive encephalitis. a causal connection was assumed only when the onset of symptoms was later than on the 7th day after the vaccination. the following parameters were evaluated; clinical symptoms, laboratory data, seasonal distribution of the neurological complications and their relationship to the total number of vaccinatio ... | 1979 | 759838 |
| lymphocyte adherence in multiple sclerosis: effect of aspirin. | peripheral blood lymphocytes from multiple sclerosis (ms) patients form substantially greater numbers of rosettes with measles virus-infected human epithelial cells than do lymphocytes from healthy controls or from patients with other diseases. we have previously shown that prostaglandin e(1)-treated normal lymphocytes exhibit increased lymphocyte adherence, and thus behave like ms lymphocytes in this in vitro system. in this study we describe the effect of prostaglandin synthesis inhibition on ... | 1979 | 762244 |
| adherence of human peripheral blood lymphocytes to measles-virus infected cells: modulation by solubilized rhesus erythrocyte membranes and carbohydrates. | the adherence of human peripheral blood lymphocytes to hela cells persistently infected with measles virus (hela-k11) was studied. the following data were observed. (i) the proportion of hela-k11 cells with adherent human peripheral blood lymphocytes of rhesus monkey erythrocytes was similar over a wide range of ratios of hela-k11 cells to lymphocytes or erythrocytes. (ii) the great majority of human peripheral blood lymphocytes and erythrocytes reacted with the same hela-k11 cell (iii). the adh ... | 1979 | 572346 |
| evaluation of the eight-year period of compulsory measles vaccination in the czech socialist republic (csr). | the object of the study is the evaluation of a more than 8-year period of compulsory vaccination against measles in the csr. so far, a total of 1,850,000 children have been vaccinated. a pronounced decrease has been achieved in morbidity while mortality and lethality reached zero values as early as in 1973. changes occur in the epidemiological characteristic of measles manifested primarily by the shift of the age distribution of notified cases into older age groups, by continuous prolongation of ... | 1979 | 575149 |
| persistent measles virus infection in a calf kidney cell line. note iii. cellular alterations in the selected chronically infected k-2 cell line. | marked morphological, growth and chromosome alterations pointing to in vitro cellular transformation were made evident in a selected calf kidney cell line (k-2) chronically infected with measles virus. the transformed cell line released infectant virus and had no oncogenic potential for the hamster. | 1979 | 575453 |
| cyclic expression of antigen and infectious virus in a bhk cell line (0-853) persistently infected with an sspe strain of measles virus. | establishment and characteristics of a baby hamster kidney cell line (bhk 0-853) persistently infected with a subacute sclerosing panencephalitis (sspe) strain of measles virus (lec strain) is described. the persistent infection was easily and repeatedly established and no special conditions were required. there was a predictable fluctuation in expression of virus intracellular and membrane antigens which varied from greater than 90% to less than 1% of the cells demonstrating these antigens duri ... | 1979 | 372496 |
| [preparation and characteristics of diploid cell strains from the tissues of a bovine embryo]. | two strains of diploid cells were prepared from the lung (bel-2) and skin-muscle (smbe-3) tissues of a bovine embryo. according to the results of morphological and karyological studies, these cultures consisted of fibroblast-like cells retaining diploid chromosome number (60) in the process of long-term cultivation. these cell populations have a limited life span (75-80 passages) and 3 growth phases. the species appurtenance of bel-2 and smbe-3 cells was confirmed. the cells were not contaminate ... | 1979 | 373247 |
| subacute sclerosing panencephalitis. immunological findings in saliva and salivary glands. | antimeasles antibody was detected in the saliva of 14 patients with subacute sclerosing panencephalitis. immunofluorescent staining showed antibody in salvary gland biopsy of 7 patients. | 1979 | 378668 |
| [eye manifestations of subacute sclerosing panencephalitis]. | a report is given on 10 children with subacute sclerosing panencephalitis (sspe) whose clinical illness began with visual or mental impairment. all patients showed typical clinical and neurologic features and various ophthalmological manifestations. the latter correspond to lesions generally dealt with in a number of reports and demonstrate for the individual case that ophthalmological manifestation can precede clinical manifestation. the ophthalmologist can give an important contribution to the ... | 1979 | 530551 |
| transmembrane communication in cells chronically infected with measles virus. | the transmembrane association of the measles virus hemagglutinin and hemolysin surface proteins with intracellular viral antigens was studied. rabbit antisera monospecific for measles virus matrix and nucleocapsid proteins and a human antiserum containing specificities for both the hemagglutinin and hemolysin proteins were used to study the co-capping of these proteins in human lu 106 cell-line, chronically infected with measles virus. capping of the surface-associated envelope components was ac ... | 1979 | 381319 |
| affinity for measles virus anti-haemolysin of a residual immunoglobulin m in sera of some patients with multiple sclerosis. | hep2 cells persistently infected with measles virus were treated with trypsin to remove haemagglutinin (ha) and examined unfixed or fixed in acetone by fluorescent antibody methods, comparing those sera specific for structural antigens of the virus. staining patterns combined with the blocking of specific immunofluorescence indicated that igg specific for measles virus haemolysin could be recognized in multiple sclerosis (ms) sera and that in some sera from which rheumatoid factor had been remov ... | 1979 | 383332 |
| detection of igg antibodies specific for measles virus by enzyme-linked immunosorbent assay (elisa). | a solid-phase, enzyme-linked immunosorbent assay (elisa) for determination of igg antibodies against measles virus is described. the assay utilized antigen-coated polystyrene microplates. the antigen consisted of a sonicated extract of measles-infected vero cells. goat and anti-human igg-peroxidase conjugate was used to detect human igg bound to viral antigen. sera taken from 63 healthy adults, 11 young children and 36 patients were evaluated for their igg titer against measles virus. comparison ... | 1979 | 387655 |
| antigen requirements, sensitivity, and specificity of enzyme immunoassays for measles and rubella viral antibodies. | enzyme immunoassay (eia) systems for measles virus and rubella virus were studied from the standpoints of requirements for suitable viral antigens and control antigens, and the sensitivity and specificity of the tests for detecting antibody elicited by past infection (determination of immunity status), and for serodiagnosis of currenet infections. crude or semipurified measles virus antigens were satisfactory for eia, but antigens derived by pelleting virus from infected cell culture fluids were ... | 1979 | 387813 |
| sspe: immunohistochemical demonstration of measles virus antigen(s) in paraffin sections. | we used the indirect immunoperoxidase method to study formalin-fixed, paraffin-embedded brain sections of four autopsied subacute sclerosing panencephalitis (sspe) patients. specific reactions with measles virus antigens was noted in all cases. positive staining was observed in neurons and glia cells and both nucleus and cytoplasm were usually stained in these positive cells. electron microscopy revealed intranuclear and intracytoplasmic nucleocapsids stained with electron-dense reaction product ... | 1979 | 388966 |
| detection of measles virus antigen(s) in peripheral lymphocytes from patients with subacute sclerosing panencephalitis. | peripheral blood lymphocytes from 5 patients with subacute sclerosing panencephalitis (sspe) were stimulated with phytohemagglutinin (pha) and analyzed for the presence of the measles virus antigen(s) by immunofluorescence (if). for detection of viral antigen fluorescein-conjugated globulins from sspe patients or from measles convalescents both with high anti-measles titer were used. peripheral blood lymphocytes from 5 children with measles were used as a positive control. measles virus antigen( ... | 1979 | 389202 |
| immunosuppressive measles encephalitis in a patient with a renal transplant. | an inclusion body encephalitis developed in a patient with a renal transplant that was shown by immunofluorescence and electron microscopic studies to be due to measles virus. measles encephalitis may be an opportunistic infection in children and adults with immunodeficiencies secondary to tumors or to the administration of immunosuppressive drugs. | 1979 | 389214 |
| the sensitivity of measles virus haemolysin to acetone and the preparation of mono-specific human anti-haemolysin by absorption. | the haemolysin of measles virus, either in the virion or in infected cells, is functionally and antigenically sensitive to acetone. absorption of human sera with acetone-treated, measles virus-infected cells removes antibodies to all measles virus structural antigens except haemolysin. the antibody titres of absorbed sera give good correlation in hli, neutralization and fluorescent antibody staining on unfixed infected cells. | 1979 | 392051 |
| [mechanisms of virus-induced and "allergic" demyelinations and their importance for the pathogenesis of multiple sclerosis. 2. the hosts reaction to virus-induced changes in the cns]. | 1979 | 396222 | |
| growth phase related loss of measles virus surface-associated antigens and cytotoxic susceptibility in persistently infected cells. | fluctuations in the expression of measles virus surface-associated antigens in persistently infected human lu 106 cells were analysed by the use of human sera which preferentially reacted with the haemolysin or haemagglutinin component. the variations observed correlated with the proportion of cells expressing surface-antigen, as examined in population analysis by indirect immunofluorescence, a radio-labelled antiglobulin technique and a cytotoxicity assay. microfluorometric analysis revealed no ... | 1979 | 396361 |
| [development of an erythrocyte diagnosticum for detecting measles antibodies]. | 1979 | 400545 |