Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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characterization and mode of action of a bacteriocin produced by a bacteroides fragilis strain. | a bacteroides fragilis strain produces a low-molecular-weight (13,500 to 18,700), proteinaceous bacteriocin during the stationary growth phase. the extracellular bacteriocin is not inducible by ultraviolet light or mitomycin c and is stable between ph 7.5 and 8.2. the majority of the bacteriocin is thermolabile, but a small proportion (3%) of the bacteriocin is stable after autoclaving at 121 degrees c for 15 min. killing of sensitive bacteroides cells follows single-hit kinetics, and the intera ... | 1979 | 93876 |
effects of exogenous gonadotropic and steroid hormones on the social behaviour and gonadal maturation of male domestic ducklings anas platyrhynchos l. | male domestic ducklings were injected during their first month of life with mammalian gonadotrophins (ovine lh or fsh, hmg) or gonadal steroids (testosterone or oestradiol). lh and testosterone stimulated sexual behaviour while oestradiol inhibited the increase of aggression observed in control birds during the experiment. the mammalian gonadotrophins did not increase plasma testosterone but nevertheless they all stimulated the testis growth. several hypotheses which could explain this finding ( ... | 1979 | 93890 |
the lac-test, a rapid method for the detection of agents inducing sos-dna repair in esch erichia coli [proceedings]. | 1979 | 93911 | |
semicarbazide-sensitive amine oxidase in rat aorta: a plasma-membrane enzyme [proceedings]. | 1979 | 93954 | |
a developmental model for studying choline acetyltransferase transport in chick motoneurons. | the proximodistal axonal transport of choline acetyltransferase (chac) has been studied in the chick sciatic nerve in the absence of any experimental manipulation. the phenomenon utilized by us is a physiological transient fall in the activity of chac. this fall occurs in most areas of the chick central nervous system after hatching, and moves toward the periphery along the nerves. having ruled out the presence of transient inhibitors, the movement of the fall towards skeletal muscles has been c ... | 1979 | 94010 |
diet composition and insulin effect on amylase to lipase ratio in pancreas of diabetic rats. | in man and in rat, the diabetic state is associated with diseases of exocrine pancreatic function. in this work, streptozotocin diabetes was shown to lead to a 95% decrease in the amylase to lipase ratio in rats. diabetes was reversed by either pancreas transplantation or insulin treatment. transplantation of neonatal pancreases was successful in reversing the diabetic-induced alterations of exocrine pancreatic function. to assess whether insulin acts directly on the exocrine pancreas, or throug ... | 1979 | 94021 |
conversion of androstenedione to estrone in human fibroblasts cultured from prostate, genital and nongenital skin. | 1979 | 94031 | |
antigenicity of casein enzymatic hydrolysate. | an enzymatic hydrolysate of bovine casein were studied for molecular size and antigenic properties. as determined by sephadex g-25 gel filtration, polypeptide fractions having molecular weights greater than 1,000 were not detected in the soluble fraction of the casein hydrolysate. antigenicity of the fraction was not detected by heterologous passive cutaneous anaphylaxis in guinea pig-rabbit antiserum system mediated by immunoglobulin g types of antibody (guinea pig passive cutaneous anaphylaxis ... | 1979 | 94065 |
correlation between morbidity and the level of serum antibodies and virus-neutralizing inhibitors in different influenza a/hong-kong epidemics. | 1979 | 94079 | |
structure of the rna portion of the rna-linked dna pieces in bacteriophage t4-infected escherichia coli cells. | 1979 | 94107 | |
[existence of r-protein antigens in group f streptococcal cells.--investigation with cells of group f streptococcal reference stain o'mahoney (colindale)]. | 1979 | 94109 | |
antifetal and tumor-specific reactivity in human osteosarcoma. | 1979 | 94187 | |
induction of delayed-type sensitivity to leishmania parasite in a case of leishmaniasis cutanea diffusa with bcg and cord-factor (trehalose-6-6' dimycolate). | the delayed hypersensitivity against the leishmania parasite was restored to a patient who had suffered from diffuse cutaneous leishmaniasis (dcl) for 26 years, by the application of an ointment containing heat-killed and lyophilized bcg and cord-factor (trehalose-6-6'-dimycolate) after stripping the affected and adjacent areas with scotch-tape. | 1979 | 94221 |
cross-reactions between haemophilus influenzae and nineteen other bacterial species. | forty-one different antigens were demonstrated in an antigen preparation obtained by sonication of a haemophilus influenzae (h. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. antigens were characterized by absorption experiments with whole heat-killed bacteria, temperature resistance and protein and polysaccharide staining. cross-reactions between h. influenzae type b and 19 other bacterial species were studied by various quantitative immunoel ... | 1979 | 94235 |
crossed immunoelectrophoretic analyses of antigens from trypanosoma lewisi and trypanosoma musculi. | 1979 | 94319 | |
chlamydia psittaci: growth characteristics and enumeration of serotypes 1 and 2 in cultured cells. | the growth characteristics of chlamydia psittaci serotypes 1 and 2 (ovine and bovine origin) were studed in mouse l cells. formation of inclusions and yield of infectious progeny for serotype 1 were maximal when host cells were treated with cycloheximide and the ph in the cell culture medium was 7.2-7.4. the number of cells that contained inclusions and the infectivity yield for serotype 2 were maximal when the ph was 6.6-7.0. treatments with diethylaminoethyl dextran and cycloheximide increased ... | 1979 | 94339 |
comparative studies on ls antigens induced by vaccinia and cowpox viruses. | the constituents of ls antigen from cells infected with vaccinia virus and with cowpox virus were compared by immunoprecipitation and sds-polyacrylamide gel electrophoresis (sds-page). antiserum to the ls antigen from cells infected with vaccinia virus reacted with at least five polypeptides in cells infected with either virus. four of these polypeptides were similar sizes in cells infected with the two viruses. however, one major polypeptide with a mol. wt. of about 100 000 (100 k) detected in ... | 1979 | 94351 |
time courses of carbachol-induced responses in guinea pig atria under the influence of ouabain, calcium, and rate of stimulation. | the response of isolated left atria of guinea pigs to carbachol was measured in the presence and during washout of the drug. the time courses of the negative inotropic effect and of the rate of shortening in action potential duration were compared. the initial rapid decline in force of contraction was followed by a slowly developing partial recovery (fading). after removal of the drug, a transient phase of hypercontractility was observed before the control level was reached again. in contrast to ... | 1979 | 94392 |
effects of subminimal inhibitory concentrations of ampicillin, chloramphenicol, and nitrofurantoin on the attachment of escherichia coli to human uroepithelial cells in vitro. | an in vitro system with epithelial cells of the human urinary tract and escherichia coli isolated from the urine of pateints with acute pyelonephritis was used for tests of the effect of antibacterial agents on bacterial adhesion. e. coli treated with subminimal inhibitory amounts of ampicillin attached less than untreated control bacteria. subminimal inhibitory amounts of chloramphenicol and nitrofurantoin had no effect on adhesion of the 15 strains of e. coli tested. the combination of bacteri ... | 1979 | 94452 |
the rate of movement of [3h]-water and [14c]-dextran into the gingival sulcus of the rabbit. | 1979 | 94543 | |
acute and chronic beta-receptor blockage with propranolol and the cardiovascular responses to intravenous sodium nitroprusside in the conscious rabbit. | sodium nitroprusside infused intravenously into conscious rabbits lowered blood pressure and raised heart rate and plasma noradrenaline. acute beta blockade with propranolol, 2 mg/kg/hr i.v. for 2 hr, increased resting plasma noradrenaline and did not change the hypotensive effects of nitroprusside or the rise in plasma noradrenaline but attenuated the increase in heart rate. chronic treatment with propranolol, 2 mg/kg twice daily for 3 weeks, did not modify the cardiovascular or reflex effects ... | 1979 | 94618 |
hla types in corneal diseases. | evaluation of the results of hla typing of 187 patients grouped into herpetic keratitis (37), non-herpetic keratitis (43), keratoconus (42), endothelial dystrophy (23), stromal dystrophy (13), lues (5), and injuries (24), failed to show convincing deviations in any of the groups from a normal control series (2900 persons). yet, as for the herpes group, a rise in b5 must strongly be suspected. the data are presented and possible implications are discussed. | 1979 | 94740 |
glucose and phosphorus utilization by two dermatophytes. | trichophyton mentagrophytes and aspergillus fumigatus dissimilated glucose through emp pathway. oxygen and inorganic phosphorus were found to control the rate and extent of glucose metabolism. | 1979 | 94752 |
determinants of 5-phosphoribosyl-1-pyrophosphate (prpp) synthesis in human fibroblasts. | 1979 | 94761 | |
[comparative study of 5 alpha-reductase activity in the prostate and the human scalp]. | 1979 | 94780 | |
a research on the action of testosterone propionate and of ciproterone acetate on the mouse-killing behaviour of the adult rat. | data demonstrate exactly that testosterone favour above all the killing behaviour of castrate males at birth in comparison with control males while ciproterone acetate turns out to be more effective in diminishing the killing behaviour of males having integral testicle and of androgenized females at birth in comparison with castrated males. the results point out that the killing behaviour of rats is affected by the presence of testosterone in the first days of life, and in the grown-up animal. | 1979 | 94826 |
chromatography of non-human albumins on cibacron blue-agarose. application to the separation of albumin from rat alpha-fetoprotein. | 1979 | 94917 | |
hepatic microsomal metabolism of epinephrine and adrenochrome by superoxide-dependent and -independent pathways. | 1979 | 31892 | |
staining of legionella pneumophila. | 1979 | 85128 | |
pharmacokinetics of the new beta-adrenoceptor blocker sl 75212 in man after repeated oral administration [proceedings]. | 1979 | 41560 | |
pseudomonas arthritis following puncture wounds of the foot. | 1979 | 34012 | |
[morphological and histoenzymatic changes in the white rat testis after long-term administration of low doses of lindan and trichlorfon (author's transl)]. | 1979 | 95555 | |
characterization of an rna-directed dna-polymerase from a cell line derived from a radiation-induced lymphoma in mice. | an rna-directed dna polymerase was purified from a cell line derived from a radiation-induced lymphoma in nih swiss mice which produced non-infectious type c virus particles. the enzyme was isolated from a high speed particulate fraction which bands at a density of 1.16--1.19 g/ml in a sucrose gradient, and purified by successive chromatography on deae-cellulose, phosphocellulose and hydroxyapatite. the purified dna polymerase has a molecular weight of 68 000, a ph optimum of 7.5, a kcl optimum ... | 1979 | 90522 |
complement profiles in monkeys subjected to aggregate (immune complex) anaphylaxis, and following injection of soluble and particulate polysaccharides. | complement profiles were established in four groups of macaca irus monkeys: (i) aggregate (immune complex) anaphylaxis was induced following immunization, with ovalbumin. upon challenge, systemic arterial pressure decreased from 115 to 50 mm hg (mean values) in 10 min. the complement profiles revealed decreases in: c1q to less than 10% of initial value within 5 min; c4 proportional to hypotension; c3 slowly to 60% at 24 h; c5, c6, c7, c8 and factor b to about 80% of initial value in 5--30 min. c ... | 1979 | 90656 |
prolonged survival of corneal allografts in rabbits treated with cyclosporin a. | 1979 | 90771 | |
maternal blocking factors in human pregnancy are found in plasma not serum. | pregnancy plasma and sera were evaluated for differential blocking effects in mixed lymphocyte culture reactions. autologous pregnancy plasma, but not serum was found to contain a specific allogeneic inhibitor for paternal lymphocytes. | 1979 | 90919 |
[vital staining of retina and uvea with trypan blue--particularly in comparison with neutral red staining (author's transl)]. | 1979 | 91316 | |
connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris). | injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ... | 1979 | 91442 |
antigen specific t cell-mediated suppression. vi. properties of in vitro generated l-glutamic acid60-l-alanine30-l-tyrosine10 (gat)-specific t-suppressor factor(s) (gat-tsf) in responder mouse strains. | 1979 | 91643 | |
histochemical studies of mucosubstances and keratins of thymic corpuscles. | keratin and prekeratin have been visualized histochemically by testing the reactivity of disulfide groups in the thymic corpuscles of the sheep. rhesus monkey, rabbit and dog, and the reactivity of sulfhydryl groups in the sheep, rhesus monkey, rabbit and rat. ten to 50% of the thymic corpuscles showed keratinization by this method. acidic mucosubstances were visualized histochemically in the rhesus monkey, sheep and rat but not in the rabbit. staining for vic-glycol groups was prominent in all ... | 1979 | 94996 |
purification of mouse interferon by sequential chromatography. | two schemes for the purification of mouse interferon are described, based on the concerted application of various physicochemical and affinity/adsorption column chromatographic techniques. mouse interferon was purified to a final specific activity of 1.0--8.0 x 10(8) units/mg when first precipitated with ammonium sulphate and further processed by hydrophobic chromatography and adsorption chromatography on affi-gel 202 and controlled pore glass. it was purified to a final specific activity of 2.5 ... | 1979 | 95020 |
comparison of antigenic properties among various strains of treponema hyodysenteriae. | agglutinin-absorption and precipitin-absorption studies demonstrated that three strains of treponema hyodysenteriae isolated from cases of swine dysentery were antigenically different from each other and also from a spirochete isolated from a clinically normal dog. each of the strains of t. hyodysenteriae also possessed two common antigens. | 1979 | 95077 |
relationship between glucan-induced agglutination and glucan-binding ability of actinomyces viscosus cells. | 1979 | 95122 | |
[structural and immunochemical studies of carp (cyprinus carpio l.) immunoglobulin. v. tryptic fragments of carp (cyprinus carpio l.) immunoglobulin m]. | carp igm, isolated from normal serum is more sensitive to trypsinization compared to a human myeloma protein igmgo. under the same conditions (treatment with trypsin at 56 degrees c for 30 min) carp igm was degraded to small, mostly dialysable peptides to a larger extent than igmgo. in both cases the fragmentation resulted in immunoelectrophoretically pure fab mu and fc mu fragments. the fab mu fragments of human igm (yield: 20% of used igm material) had a molecular weight of 54,000, the fc mu f ... | 1979 | 95144 |
antigenic similarity between squamous cell carcinoma of horn (horn cancer) and normal bovine foetal tissues. | normal bovine foetal (liver and skin) and horn cancer tissue antigens were examined using double diffusion agar gel precipitation and immuno-electrophoretic tests to detect any cross reactivity among them. rabbit horn cancer antisera absorbed with normal bovine liver, skin and horn core epithelium antigens, when tested with foetal skin and liver (4 to 6 months of gestation), revealed the presence of 2 foetal antigens in horn cancer. immuno-chemically 2 of the horn cancer antigens were found to b ... | 1979 | 95358 |
[antitumor activity and preclinical pharmacologic evaluation of pingyangmycin (author's transl)]. | 1979 | 95444 | |
[effects of ddt and aldrin on swine cell line ib-rs-2]. | swine cells ib-rs-2 were exposed to 0,1-100 microgram/ml medium of ddt and aldrin for 48 hours. the data obtained showed that both compounds decreased cell growth. this effect depends on the concentration and on the time of cell exposition to the insecticides. these compounds also decreased the levels of cellular protein, rna and dna. the degrees of changes with aldrin were less than with ddt. | 1979 | 95479 |
autonomic block, cardiovascular depression and histamine release produced by polymyxin b in the cat. | the present study quantifies the autonomic block, the cardiovascular depression and the histamine releasing effects of polymyxin b in nine anaesthetized cats. the dose requirements for 50 per cent depression of the mean arterial blood pressure, the bradycardiac response to vagal stimulation, and the contraction of the nictitating membrane elicited by pre-ganglionic and post-ganglionic stimulation of the cervical sympathetic trunk have a narrow range of scatter, being of the order of 6--12 mg.kg- ... | 1979 | 89005 |
reaction of cells from early chick embryos with antiserum against mouse sperm cells. | 1979 | 89009 | |
nonspecific suppressor cell activity and specific cellular unresponsiveness in rat schistosomiasis. | 1979 | 89037 | |
immunological unresponsiveness in mice. ii. cellular basis of immunological unresponsiveness induced in foetal and neonatal mice by transfer of human gamma-globulin by the maternal route. | the cellular basis of the mechanism of immunological tolerance to human gamma-globulin (h gamma g) induced in foetal and neonatal mice by materno-foetal or materno-neonatal transfer after a single injection of tolerogen (deaggregated h gamma g) into the mothers was investigated using a cell transfer system and assays of passive haemagglutinating antibodies and plaque-forming cells to h gamma g. the results demonstrated that b cells are mainly involved in the tolerance induced on the fourteenth d ... | 1979 | 89080 |
preliminary studies on nasal decongestant activity from the seed of the shea butter tree, butyrospermum parkii. | 1 the seed of butyrospermum parkii yields shea butter which according to local traditional healers relieves inflammation of the nostrils. 2 since there is as yet no absolutely satisfactory nasal decongestant in clinical use, it was decided to investigate the effects of shea butter in nasal congestion. the substance was prepared in the laboratory. 3 the human subjects used were those suffering from rhinitis with moderate to severe nasal congestion. they were divided into the test group which rece ... | 1979 | 89854 |
the cellular basis of transplantation tolerance in the rat. | 1979 | 90010 | |
immunofluorescent staining of platelet suspensions and detection of antiplatelet antibody in patients with idiopathic thrombocytopenic purpura. | direct immunofluorescent staining of 31 specimens of platelets obtained from 13 cases of idiopathic thrombocytopenic purpura (itp) revealed positive staining on the surface of platelets for both immunoglobulins (igs) and human b1c globulin in 9 specimens, for only igs in 1 specimen and for human b1c alone in 5 specimens. the pattern of the positive immunofluorescent staining was granular. indirect immunofluorescent staining of normal platelets in serum obtained from patients with itp was positiv ... | 1979 | 88810 |
differentiation between cyclic amp level and allergic histamine release in mast cells [proceedings]. | 1979 | 88891 | |
goitrogens. | 1979 | 85506 | |
comparison of the temperature-dependence of rapid axonal transport and microtubules in nerves of the rabbit and bullfrog. | 1. the average velocity of transport of dopamine-beta-hydroxylase, an enzyme confined to unmyelinated adrenergic nerves, was measured in rabbit and bullfrog sciatic nerves or branches incubated in vitro at various temperatures. in parallel experiments, the number and density of microtubules were measured in cross-sections of randomly selected unmyelinated axons from another set of nerves incubated under the same conditions. 2. average transport velocity was exponentially related to temperature o ... | 1979 | 85705 |
definition of two ld antigens in rhesus monkeys. | two rhesus (macaca mulatta) monkey lymphocyte-defined (ld) antigens have been identified using two typing cells as stiumlators in a one-way mixed leukocyte culture (mlc) assay. an analysis of the genetic behavior of these ld antigens in six rhesus monkey families revealed that both antigens were linked with rhla. one probable recombinant indicated that the ld locus lies outside the two known rhla-sd loci and the locus which controls the serum protein, properdin b(bf). these two antigens, ld1 and ... | 1979 | 87026 |
similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice. | amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ... | 1979 | 87374 |
moloney virus-induced cell surface antigens and histocompatibility antigens are located on distinct molecules. | 1979 | 87439 | |
some progress with nasopharyngeal carcinoma. | 1979 | 87621 | |
repair and late degeneration of the primate foveola after injury by argon laser. | each foveola of nine rhesus monkey eyes was subjected to a single, mild, calibrated exposure from an argon laser (1 to 1.4 mw for 10 to 20 min). observations from ophthalmoscopy, fundus photography, and fluorescein angiography were correlated with light and electron microscopic studies. the ophthalmoscopic changes consisted of initial whitening and subsequent but persistent depigmentation of the foveola. fluorescein angiography showed a pattern consistent with "window defect" of the retinal pigm ... | 1979 | 108229 |
preparation and antibacterial activity upon micrococcus luteus of derivatives of iturin a, mycosubtilin and bacillomycin l, antibiotics from bacillus subtilis. | methylated and acetylated derivatives of iturin a and mycosubtilin and methylated derivatives of bacillomycin l were prepared and their antibacterial activity on micrococcus luteus was compared with the activity of the original substance. the results obtained show the importance of polar groups for the antibiotic activity of the substances of iturin group. | 1979 | 108238 |
modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase. | nalidixic acid (nal), a drug which affects deoxyribonucleic acid gyrase activity, inhibits the expression of catabolite-sensitive genes: the three maltose operons, the lactose and galactose operons, and the tryptophanase gene. a correlation between the degree of sensitivity to nal and that to catabolite repression has been observed. the expression of the threonine and tryptophan operons, insensitive to catabolite repression, is insensitive to nal. the expression of the lacz gene under the contro ... | 1979 | 108253 |
demonstration and characterization of specific binding sites for factor viii/von willebrand factor on human platelets. | the presence of specific factor viii/von willebrand factor (fviii/vwf) binding sites on human platelets has been demonstrated by using 125i-fviii/vwf and washed human platelets. binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. binding of 125i-fviii/vwf to platelets can be competitively inhibited by unlabeled human or bovine fviii/vwf, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of ri ... | 1979 | 108291 |
effect of n-trifluoroacetyl derivatives of amino acids and amino acid analogs on microbial antitumor screen. | eighteen trifluoroacetyl derivatives of amino acids and of amino acid analogs were prepared and tested for growth-inhibitory activity using a lactobacillus casei system as a prescreen for antitumor activity. of the compounds tested, the trifluoroacetyl derivatives of o-, m-, and p-fluorophenylalanine and of beta-3-thienylalanine showed modest activity; trifluoroacetyl derivatives of phenylalanine and of beta-2-thienylalanine showed marginal activity. the activity exhibited by the active trifluor ... | 1979 | 108385 |
[tuberculosis and changes in the tissue lipids]. | 1979 | 108447 | |
pantothenase. | 1979 | 108511 | |
isolation of an influenza virus subtype hav4navl from a budgerigar. | 1979 | 108521 | |
response of periapical pathosis to endodontic treatment in monkeys. | response of induced periapical lesions in monkeys to a conventional endodontic technique was investigated at varying periods ranging from 15 to 365 days after treatment. the findings indicate that response to treatment is influenced by the extent of the root canal filling, the time lapse between treatment and death, and the presence or absence of bacteria in the apical portion of the canal. | 1979 | 108648 |
[effect of microsporidiosis on the fertility of aedes caspius caspius (culicidae) mosquitoes]. | effect of microsporidiosis on the fecundity of hosts a. c. caspius was studied. the calculation of eggs in hatches has shown that females developing from infected eggs lay 2--3 times lesser eggs than non-infected ones. besides, the number of females laying eggs decreases considerably. despite the females of mosquitoes suck blood before each egglaying the disease, which proceeds at their larval stage, affects greatly their fecundity. additional feeding of females cannot compensate completely the ... | 1979 | 108654 |
polydipsia in the monkey generated by visual display schedules. | 1979 | 108693 | |
the effects of alcohol on agonistic behavior in the telomian dog. | the study analyzed the effects of alcohol on agonistic behavior in three independent social systems, each compromised of two male and one female telomian dog. three dose levels were used: 0, 0.8, and 1.6 g/kg body weight of absolute alcohol diluted to 20%. observations were made when none, one (top, middle or low ranking), or all dogs in a system received a given treatment. at the 0.8 g/kg level, low ranking dogs showed an increased frequency of attacks and bone possession time, while top and mi ... | 1979 | 108707 |
piracetam facilitates retrieval but does not impair extinction of bar-pressing in rats. | rats were trained on a continuously reinforced bar-press response for water reward. seven days later they were retested for retention, with or without pretest injection of the nootropic drug, piracetam. drug-treated animals had significantly shorter response latencies than saline-treated animals. the results are interpreted as a facilitation of retrieval processes after forgetting. the experiment was extended under extinction conditions and it was found that after three sessions there was a tend ... | 1979 | 108722 |
sex differences in behavioral and thermal responses to pargyline and tryptophan. | the effects of parenterally injected pargyline and tryptophan on rectal temperature and behavior have been studied in male and female rats. pargyline alone (50 mg/kg) produced hypothermia in both sexes. pargyline (50 mg/kg) followed by low doses (20--50 mg/kg) of tryptophan caused a behavioral syndrome consisting of tremor, hindlimb abduction, forepaw treading, and straub tail. in females, but not in males, hypothermia was potentiated. the same dose of pargyline followed by higher doses (60--150 ... | 1979 | 108723 |
dietary modification of amphetamine stereotyped behaviour: the action of tryptophan, methionine, and lysine. | rats fed diets high in tryptophan, methionine, and tryptophan plus methionine or lysine were subsequently injected with 10 mg/kg d-amphetamine. the amount of amphetamine-induced stereotyped behaviour observed varied as a function of the dietary addition, with methionine showing the greatest difference to controls, and lysine the least. whole brain catecholamine levels and 5-hydroxytryptamine levels also showed amino acid-specific changes. | 1979 | 108724 |
enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: relevance to the mechanism of the antidepressive effect of electroconvulsive therapy. | treatment of rats with one electroconvulsive shock (ecs) per day for 10 days enhanced the hyperactivity syndrome produced by administration of tranylcypromine (10 mg kg-1) and l-tryptophan (50 mg kg-1) given 24 h after the final shock. similar enhancement was seen whether the shock was alternating sinusoidal or direct current (fractionated), whether it was given through unilaterally or bilaterally placed electrodes and whether or not a neuromuscular blocking agent (fazadinium) was used. five sho ... | 1979 | 108733 |
comparison of the discriminative stimulus properties of nefopam and morphine. | separate groups of rats were trained to discriminate nefopam or morphine from saline in a two-lever operant task. nefopam produced saline-appropriate responding in morphine-trained rats. the highest dose of morphine tested in nefopam-trained rats produced responding appropriate for neither training treatment. this intermediate morphine responding was antagonized by a naloxone treatment that had no effect on the nefopam discrimination. these results suggest that the stimulus properties of nefopam ... | 1979 | 108741 |
cardiac imaging with tantalum-178. | tantalum-178 is a potential tracer for the first transit studies of the heart. it has a short physical half-life (9.3 minutes) and is obtained as a generator product from its long-lived (21.3 days) parent, tungsten-178. first transit studies were performed in the monkey and dog following the intravenous injection of 20 mci (740 mbq) of tantalum-178. imaging was performed with a large field of view single crystal camera and a multicrystal camera. pulmonary dilution curves were derived for the ana ... | 1979 | 108764 |
[multiple molecular forms of erythrocyte carbonic anhydrase of sheep (author's transl)]. | three major forms ci, cii and cx and the minor component ci1v of ovine erythrocyte carbonic anhydrase have been identified in the ethanol chloroform extract of the hemolysate by electrophoresis on cellulose acetate and isoelectrofocusing. isolation of the four forms was achieved by chromatography on deae-sephadex a-50. comparative studies suggest that: (1) form ci1v is a modified form of ci, (2) form cx is ci plus glutathione and (3) forms ci and cii are isoenzymes which differ in their primary ... | 1979 | 106895 |
baroreceptor control of atrioventricular conduction in man. | although human baroreflexes are known to exert a powerful physiological control on heart rate, little information exists on the physiological control they exert on the atrioventricular conduction system. in 11 normotensive subjects with normal atrioventricular conduction, we altered baroreceptor activity by injection of pressor and depressor drugs (phenylephrine and trinitroglycerin) and recorded mean arterial pressure (map, catheter measurements), r-r interval, and pre-his and post-his interval ... | 1979 | 106985 |
liver transplantation. | 1979 | 107000 | |
effect of pregnancy and lactation on glycosyltransferase activities of rat mammary gland. | 1979 | 107054 | |
rapid demineralization in acidic buffers. | the demineralization of routine histological specimens in buffers of weakly ionized organic acids, unbuffered formic acid, and edta was investigated. the rate of demineralization was measured by a chemical method and from radiographs. lactate-containing buffers and buffers of formic acid with its potassium salt were more rapid in effect than any other agent. acidic buffers and unbuffered formic acid produced rapid diffuse demineralization with secondary precipitation of calcium salts. preservati ... | 1979 | 107151 |
regulation of teichoic acid synthesis during phosphate limitation. | bacillus subtilis w-23, when placed in phosphate-free medium, ceases to synthesize teichoic acid and synthesizes teichuronic acid. the enzymatic basis for the cessation of teichoic acid synthesis is the irreversible inhibition of the first membrane-bound enzyme involved in teichoic acid synthesis which catalyzes the reaction undecapenol-p + udp-glcnac leads to undecaprenol-p-p-glcnac + ump. | 1979 | 107156 |
alcohol, malnutrition and liver disease. | 1979 | 107268 | |
dietary protein, aryl hydrocarbon hydroxylase and chemical carcinogenesis in rats. | 1979 | 107295 | |
effects of dietary composition on somatomedin activity in growing rats. | 1979 | 107298 | |
tumor-host responses to various nutritional feeding procedures in rats. | parenteral and enteral nutrition are being used as adjuncts to cancer therapy. a liquid diet formulation containing a 27% solution of glucose and 3.9% crystalline amino acids with electrolytes and vitamins was given continuously for a week via parenteral (iv), and via intragastric (ig) routes and also was given ad libitum via the oral or per os (po) route to groups of buffalo rats with and without a morris no. 7777 transplantable hepatoma to find out how these feeding procedures affect tumor-hos ... | 1979 | 107299 |
rna polymerase binding sites and transcription map of the dna of bacillus subtilis phage phi29. | 1979 | 107317 | |
retinal pigment epithelium. interrelations of endoplasmic reticulum and melanolysosomes in the black mouse and its beige mutant. | by cytochemistry (acid phosphatase and tyrosinase activities) gerl, a specialized hydrolase-rich region of endoplasmic reticulum (er), can be visualized in the cells of the mouse retinal pigment epithelium. previously catalase cytochemistry permitted us to identify microperoxisomes, with numerous continuities to the er. the present report reveals the extensive continuities of the er to pigment granules in various stages of maturation. when the pigment granules, which we consider to be "melanolys ... | 1979 | 107366 |
[the isolation of chlamydia in the male urogenital tract]. | 1979 | 107412 | |
distribution of visual and somatic functions in the parietal associative area 7 of the monkey. | 1979 | 109170 | |
comparative behavioral effects of clorgyline and pargyline in man: a preliminary evaluation. | the antidepressant and other behavioral effects of clorgyline, a preferential inhibitor of monoamine oxidase (mao) type a, were compared with those of pargyline, a preferential inhibitor of mao type b, in 16 depressed patients. in a subgroup of more severely depressed patients, clorgyline treatment for 4 weeks resulted in significant improvement on both observer-rated and self-rated scales, while minimal changes occurred during pargyline treatment. similarly, in a crossover study that included 8 ... | 1979 | 111274 |
arthrosonography: gray-scale ultrasound evaluation of the shoulder. | gray-scale ultrasound images of the shoulders of 6 rhesus monkeys were obtained before and after fluid instillation to assess the ability of ultrasound to diagnose joint disorders. the normal bony landmarks and muscular structures were shown. after the fluid was introduced, fluid collections were identified in the axillary pouch and subscapular bursa. ultrasound is a promising new method of detecting intra-articular effusions of the shoulder. | 1979 | 111302 |
subsets of t lymphocytes and lymphocyte cooperation. modulation of the immunocellular response. | recent advances in the characterization of t cell subsets suggests that the various subsets of t cells described in mice also occur in man. these various subsets of t cells can be detected by the use of appropriated antisera, co-cultivation of purified lymphoid cell preparations and differential sensitivity to radiation. clinical applications from these new observations are now underway and it is hopeful that they should help to achieve a better understanding of the mechanisms responsible for au ... | 1979 | 111313 |
[antibacterial immunity in diphtheria. experimental research]. | a number of 700 guinea pigs were immunized by parenteral route with non-toxigenic corynebacterium diphtheriae strains, then inoculated with various doses of homologous and heterologous toxigenic c. diphitheriae strains. the results showed that non-toxigenic c. diphtheriae strains confer a certain degree of protection when the challenge is done with homologous toxigenous strains, especially when not more than 500 million germs/ml are used for the challenge dose. this suggests that the carriage of ... | 1979 | 111333 |
[rapid methods useful for determination of streptococcal groups with special reference to streptococci of groups b and d]. | a study was carried out on the efficiency of certain rapid methods for the identification of streptococcal groups, especially groups b and d, methods based upon physiologic properties such as hippurate hydrolysis, production of pigment, esculin hydrolysis, tolerance to salt and bilolysis, associated with the classical tests, for instance the hemolysis type and sensitivity to bacitracin and optochin. by these tests, accessible to hospital laboratories, a number of 3083 streptococcal strains were ... | 1979 | 111335 |
methylation status of intracellular dengue type 2 40 s rna. | 1979 | 111410 | |
vasopressin release and drinking induced by intracranial injection of angiotensin ii in monkey. | the effects of intracerebral injection of angiotensin ii (aii) on both water intake and arginine-vasopressin (avp) release were tested on unanesthetized rhesus monkeys (macaca mulatta). injection of 10(-10) mol of peptide was administered with a cannula microinjection system stereotaxically implanted into different diencephalic structures. the preoptic area, anterior part of third ventricle, caudate nucleus, and septum appeared to be the injection sites most effective in eliciting both drinking ... | 1979 | 111563 |