Publications

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gene-enzyme relationships in histidine biosynthesis in aspergillus nidulans. 19675583728
on the mechanism of mitotic recombination in aspergillus nidulans. i. intragenic recombination and dna replication. 19675584173
on the mechanism of mitotic recombination in aspergillus nidulans. ii. simultaneous recombination within two closely linked cistrons. 19675584174
a vegetative insatability in aspergillus nidulans. 19675586877
aromatic amino acid biosynthesis and para-fluorophenylalanine resistance in aspergillus nidulans. 19675587942
isolation from aspergillus nidulans, of a protein catalyzing the reduction of sulfite by reduced viologen dyes. 19675589532
use of analogues and the substrate-sensitivity of mutants in analysis of purine uptake and breakdown in aspergillus nidulans.aspergillus mutants resistant to various purine analogues (purine, 8-azaguanine, 2-thioxanthine, and 2-thiouric acid) are defective in at least one step of purine uptake or breakdown. the properties of these mutants show that there are two uptake systems for purines, one which mediates the uptake of hypoxanthine, guanine, and adenine, and the other, xanthine and uric acid. allantoinase-less strains are sensitive to the toxic effects of allantoin accumulation. they are severely inhibited when gro ...19676025432
complementation analysis of the tryptophan pathway in aspergillus nidulans. 19676029969
enzyme analysis of the tryptophan pathway in aspergillus nidulans. 19676029970
purification of two alkaline phosphatases from aspergillus nidulans. 19676030350
the mechanism of action of proline suppressors in aspergillus nidulans. 19676034041
genetic and cytoplasmic control of undifferentiated growth in aspergillus nidulans. 19676034180
inhibition of the lysis of fungi by melanins.evidence is presented that the resistance of aspergillus nidulans hyphae to lysis by a beta-(1-->3) glucanase-chitinase mixture results from the presence of melanin in the fungal walls. the resistance of the walls to digestion was directly correlated with the melanin content of the mycelium. a melanin-less mutant of a. nidulans was highly susceptible to hydrolysis by the enzyme mixture. preincubation of a synthetic melanin with the glucanase, chitinase, and a protease, before addition of the sub ...19676035264
kinetic studies of the induction of nitrate reductase and cytochrome c reductase in the fungus aspergillus nidulans.in an earlier paper (cove, 1966) it was reported that the kinetics of appearance of nitrate reductase (nadph-nitrate oxidoreductase, ec 1.6.6.3) on the addition of nitrate to a growing culture of aspergillus nidulans were different in certain respects from those found for many escherichia coli enzymes. when urea is used as an initial nitrogen source, a further difference is found: enzyme synthesis is no longer continuous. this interruption of synthesis does not appear to be due to synchronous ce ...19676049855
regulation of nitrate reduction in aspergillus nidulans. 19676052720
a system for the study of interlocus specificity for both forward and reverse mutation in at least eight gene loci in aspergillus nidulans. 19676054957
synchrony of nuclear replication in individual hyphae of aspergillus nidulans.the synchrony of nuclear replication in individual, multinucleate hyphae of aspergillus nidulans has been investigated. samples were taken from cultures of germinating conidiospores, and the relative frequency of hyphae containing two to eight nuclei was determined. because the conidiospores are mononucleate, complete synchrony will yield populations of hyphae containing only 2(n) nuclei, n being the number of doublings after germination. the appearance of hyphae with total numbers of nuclei oth ...19676057801
a revised map of the eight linkage groups of aspergillus nidulans. 19676061654
chromosome instability related to gene suppression in aspergillus nidulans. 19676064104
lethal mutations and balanced lethal systems in aspergillus nidulans. 19676064441
genetic and biochemical studies of nitrate reduction in aspergillus nidulans.1. in aspergillus nidulans nitrate and nitrite induce nitrate reductase, nitrite reductase and hydroxylamine reductase, and ammonium represses the three enzymes. 2. nitrate reductase can donate electrons to a wide variety of acceptors in addition to nitrate. these artificial acceptors include benzyl viologen, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride, cytochrome c and potassium ferricyanide. similarly nitrite reductase and hydroxylamine reductase (which are possibly a singl ...19674382427
induction of inter- and intragenic mitotic recombination by fluorodeoxyuridine and fluorouracil in aspergillus nidulans. 19674226822
the stoicheiometry of electron transfer by bacterial and plant ferredoxins.1. the number of electrons carried by ferredoxins from spinach, the blue-green alga anacystis nidulans, the anaerobic bacterium clostridium welchii and the photosynthetic bacterium chromatium was determined. 2. ferredoxins were reduced by illuminated chloroplasts, and the stoicheiometry of the reoxidation in the dark of the ferredoxins by nadp and benzyl viologen was measured. 3. spinach and a. nidulans ferredoxins were found to be one-electron carriers, and cl. welchii and chromatium ferredoxin ...19684387387
methionine loci and their suppressors in aspergillus nidulans. 19684885981
karyokinesis of the somatic nucleus of aspergillus nidulans. ii. nuclear events during hyphal differentiation. 19684180480
the relationship between sexual outcrossing and heterokaryon incompatibility in aspergillus nidulans. 19685250125
penicillin production and its mode of inheritance in aspergillus nidulans. 19684973904
mechanism of choline o-sulphate utilization in fungi.1. the position of the enzyme blocks in a number of parathiotrophic mutants of aspergillus nidulans a 69 and mutants a and c of a biotinless mutant of aspergillus nidulans were examined by nutritional and heterokaryosis experiments and by assay in vitro of enzyme systems and specific enzymes. 2. the mutants were in five groups: a and c blocked at sulphate transport; gamma at atp sulphurylase; iota at adenosine 5'-sulphatophosphate kinase; eta at the adenosine 3'-phosphate 5'-sulphatophosphate re ...19685637353
regulation of choline sulphatase synthesis and activity in aspergillus nidulans.1. choline o-sulphate is taken up from the growth medium to the same extent by sulphur-deficient and sulphur-sufficient mycelia of aspergillus nidulans, but hydrolysis of the transported sulphate ester in vivo only occurs in the sulphur-deficient mycelia. 2. choline sulphatase activity could not be detected in vitro in sulphur-sufficient mycelia of wild-type and sulphur mutants of a. nidulans, but after sulphur starvation all strains showed appreciable activity of this enzyme. 3. optimum activit ...19685637354
purification and characterization of phosphatase i from aspergillus nidulans. 19685656385
genetic fine structure and polarized negative inteference at the lys-51(fl) locus of aspergillus nidulans. 19685658755
regulation of sugar utilization by aspergillus nidulans. 19685660115
[aspergillosis of the lung caused by aspergillus nidulans (eidam) wint]. 19685660496
a radiation-sensitive mutant of aspergillus nidulans. 19685660770
quantitative intrachromosomal changes arising at mitosis in aspergillus nidulans. 19685664384
isolation of strains with increased penicillin yield after hybridization in aspergillus nidulans. 19685665723
regulation and timing of deoxyribonucleic acid synthesis in hyphae of aspergillus nidulans.pulse labeling of deoxyribonucleic acid (dna) and radioautography have been used to study the effect of growth rate on nuclear replication in aspergillus nidulans. when conidia were germinated in media supporting a fast growth rate, the radioactive pulse labeled either all of the nuclei in a cell or none of them. at slower growth rates, hyphae contained both labeled and unlabeled nuclei. altering the growth rate thus changed nuclear replication from simultaneous to sequential. the time taken to ...19685669900
genetic analysis of the first steps of sulphate metabolism in aspergillus nidulans. 19685671427
induced mutation in uv-sensitive mutants of aspergillus nidulans and neurospora crassa. 19685672966
glucose metabolism in aspergillus nidulans. 19685677993
the induction and repression of the enzymes of purine breakdown in aspergillus nidulans. 19685680610
evidence for an alternative pathway of xanthine oxidation in aspergillus nidulans. 19685680611
metabolic changes in biotin-deficient aspergillus nidulans. 19685684683
the nature of mitotic intragenic recombination in aspergillus nidulans. 19685685164
nonrandom sister chromatid segregation and nuclear migration in hyphae of aspergillus nidulans.radioactive conidiospores of aspergillus nidulans were prepared by growing a purine-requiring mutant with tritiated adenine. when these spores germinated in a nonradioactive medium, the dispersion of the original chromosome set could be followed by treating the hyphae with ribonuclease and preparing radioautograms. germinating spores with four or eight nuclei contained two highly labeled nuclei and two or six nuclei with much less or no radioactivity. successive mitotic divisions thus distribute ...19685685997
[recent contribution to the study of mycetoma in senegal. neotestudina rosatii. pyrenochaeta romeroi. aspergillus nidulans]. 19685713774
influence of chromosomal aberrations on meiotic and mitotic nondisjunction in aspergillus nidulans. 19685732416
sexual and asexual phases of aspergillus nidulans in an egret. 19685750671
[aspergillus nidulans, agent of mycetoma]. 19685756586
cell volume per nucleus in haploid and diploid strains of aspergillus nidulans. 19695764740
mutants of the arginine-proline pathway in aspergillus nidulans. 19695764741
autoregulation of the synthesis of nitrate reductase in aspergillus nidulans.in aspergillus nidulans, the syntheses of nitrate and nitrite reductases are induced by nitrate, and are repressed by ammonium. it is possible in wild-type strains to overcome partially the repressive effect of ammonium, by the addition of high concentrations of nitrate to the growth medium. mutations which lead to the production of abnormal nitrate reductase affect in addition the control of the synthesis of the nitrate-metabolizing enzymes, which in these strains are produced constitutively. t ...19695776531
methylammonium resistance in aspergillus nidulans.mutants of aspergillus nidulans resistant to methylammonium toxicity are simultaneously derepressed in the presence of ammonium for apparently all ammonium-repressible activities. enzyme assays directly demonstrate derepression of nitrate, nitrite, and hydroxylamine reductases, xanthine dehydrogenase, urate oxidase, and allantoinase, whereas in vivo tests show that ammonium and methylammonium repression or inhibition (or both) is relieved in these mutants in pathways of nitrate assimilation, pur ...19695788705
reversion of non-nitrate utilizing (nia d) mutants of aspergillus nidulans. 19695796514
permeability properties of aspergillus nidulans protoplasts.the regeneration of mycelial forms from protoplasts of mutant and wild-type strains of aspergillus nidulans was followed microscopically under conditions with which the rate of regeneration depends upon a specific transport function. this method has shown that at least four uptake systems-one for divalent anions, two for purines, and one for sugars-remain functional after removal of the cell wall.19695802597
organization of enzymes in the common aromatic synthetic pathway: evidence for aggregation in fungi.centrifugation in sucrose density gradients of partially purified extracts from six species of fungi, i.e., rhizopus stolonifer, phycomyces nitens, absidia glauca (phycomycetes), aspergillus nidulans (ascomycetes), coprinus lagopus, and ustilago maydis (basidiomycetes), indicate that the five enzymes catalyzing steps two to six in the prechorismic acid part of the polyaromatic synthetic pathway sediment together. the sedimentation coefficients for these enzymes are very similar in the six specie ...19695802608
uv-sensitive mutants increasing mitotic crossing-over in aspergillus nidulans. 19695807344
melanin production in aspergillus nidulans. 19695810076
a kinetic study of the growth of aspergillus nidulans and other fungi. 19695822157
the formation of udp-glucose and udp-galactose in wild type and mutants of aspergillus nidulans. 19695346712
evidence against necessary phosphorylation during hexose transport in aspergillus nidulans.the transport of 2-deoxy-d-glucose, a nonmetabolizable glucose analogue, into aspergillus nidulans against a concentration gradient does not appear to require phosphorylation, despite the high levels of sugar phosphates accumulated rapidly within the cell. two other deoxy analogues of d-glucose, 6-deoxy-d-glucose and 1,5-anhydro-d-glucitol (1-deoxy-d-glucose), although they lack the c-6 and the c-1 hydroxyl groups, respectively, and thus cannot be phosphorylated in those positions, still competi ...19695361211
effects of lysine on arginine uptake and metabolism in aspergillus nidulans. 19695364466
a system generating spontaneous intrachromosomal changes at mitosis in aspergillus nidulans. 19695364959
specificity for spontaneous and induced forward mutation at several gene loci in aspergillus nidulans. 19695366006
effects of liquid holding on the induction of mutations in an ultraviolet-sensitive strain of aspergillus nidulans. 19695366007
a mutational analysis of conidial development in aspergillus nidulans. 19695366214
mitotic non-conformity in aspergillus nidulans: the production of hypodiploid and hypohaploid nuclei. 19695367366
methionine suppressors in aspergillus nidulans: their genetics and behaviour in heterokaryons and diploids. 19695367377
surface characteristics of conidia from monosporous cultures of penicillium digitatum and aspergillus nidulans var. echinulatus. 19695369330
spontaneous and induced reversion of icr-170-induced xanthine dehydrogenase mutants of aspergillus nidulans. 19695370743
genetic control of the uptake of amino acids in aspergillus nidulans. 19695384482
effects of ultraviolet irradiation on heterozygous diploids of aspergillus nidulans. i. uv-induced mitotic crossing over. 19695384483
[comparison of the mutagenic effect of chemically similar bifunctional nitrogen mustard gases on aspergillus nidulans]. 19695397319
effects of ultraviolet irradiation on heterozygous diploids of aspergillus nidulans. ii. recovery from uv-induced mutation in mitotic recombinant sectors. 19695399400
phenol oxidases produced by mutant and wild-type strains of aspergillus nidulans. 19694980308
non-allelic interactions and genetic isolation in wild populations of aspergillus nidulans. 19695262865
mitosis in aspergillus nidulans. 19694188529
[on the frequency of aflatoxin and aspergillus in foods]. 19694259173
[mycotoxins produced by aspergillus. their action on the chick embryo]. 19694259296
regulation of synthesis of glutamate dehydrogenase and glutamine synthetase in micro-organisms.1. aspergillus nidulans, neurospora crassa and escherichia coli were grown on media containing a range of concentrations of nitrate, or ammonia, or urea, or l-glutamate, or l-glutamine as the sole source of nitrogen and the glutamate dehydrogenate and glutamine synthetase of the cells measured. 2. aspergillus, neurospora and escherichia coli cells, grown on l-glutamate or on high concentrations of ammonia or on high concentrations of urea, possessed low glutamate dehydrogenase activity compared ...19694901826
genetic analysis of "somatic" cells in filamentous fungi. 19694947200
the pinkish red pigment produced by an adenineless mutant of aspergillus nidulans. 19694245435
differential transcription of t(4)-dna by dna-dependent rna-polymerase of e. coli and a. nidulans. 196911946973
action spectra for photosystems i and ii in formaldehyde fixed algae.action spectra were obtained for photosystems i and ii in chemically fixed algal cells and for photosystem i in unfixed lysozyme treated cells. untreated algal cells yielded neither of the 2 light reactions with the reaction mixtures used. the action spectra for photosystem i in the blue-green alga anacystis nidulans and red alga porphyridium cruentum follow the absorption spectrum of chlorophyll a with a small peak in the region of the accessory pigments. in the green alga chlorella pyrenoidosa ...196916657098
regulation of sulfate transport in filamentous fungi.inorganic sulfate enters the mycelia of aspergillus nidulans, penicillium chrysogenum, and penicillium notatum by a temperature-, energy-, ph-, ionic strength-, and concentration-dependent transport system ("permease"). transport is unidirectional. in the presence of excess external sulfate, atp sulfurylase-negative mutants will accumulate inorganic sulfate intracellularly to a level of about 0.04 m. the intracellular sulfate can be retained against a concentration gradient. retention is not ene ...197016657536
the role of isocitrate lyase in aspergillus nidulans. 197011947479
immunological differences between inducible and constitutive xanthine dehydrogenases in aspergillus nidulans. 197011945540
control of gene action in aspergillus nidulans. 19704395097
molybdate metabolism in aspergillus nidulans. ii. mutations affecting phosphatase activity or galactose utilization. 19704319916
mitochondrial ribosomal rna from aspergillus nidulans: characterization of a novel molecular species. 19704915865
size determination of mitochondrial ribosomal rna from aspergillus nidulans by electron microscopy. 19704922208
further genetic characteristics of methionine mutants and their suppressors in aspergillus nidulans. 19704924133
genetic and accumulation studies in sulfite-requiring mutants of aspergillus nidulans. 19704934393
further genetic characteristics of methionine mutants and their suppressors in aspergillus nidulans. 19704937573
the genetic analysis of regulation of amidase synthesis in aspergillus nidulans. ii. mutants resistant to fluoroacetamide. 19704097637
the use of amides as nitrogen sources by aspergillus nidulans. 19704102613
x-ray sensitivity and modifying effects of water in conidia of aspergillus nidulans. 19704990085
[comparative study of antigenic structure by immunoelectrophoretic analysis and by characterization reactions of enzymatic activities of the antigenic extracts of pathogenic fungi of the genus aspergillus (a. fumigatus, a. flavus, a. terreus and a. nidulans)]. 19704995145
[nidulotoxin: the toxin of aspergillus nidulans wint]. 19705412300
enzyme lesions in galactose non-utilising mutants of aspergillus nidulans. 19705418725
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