Publications

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[on the significance of endotoxin in experimental typhoid. i. extraction of endotoxin from mutants of salmonella enteritidis and the effect of the endotoxin on infection in mice caused by those strains]. 196214478191
[action of the optical antipodes of threonine on the growth of salmonella enteritidis thyphimurium and of proteus vulgaris x.19]. 196214479578
acquired immunity to candidiasis in mice.hasenclever, h. f. (national institute of allergy and infectious diseases, bethesda, md.) and william o. mitchell. acquired immunity to candidiasis in mice. j. bacteriol. 86:401-406. 1963.-some protection to chronic candidiasis in mice was produced by sublethal intraperitoneal infection with candida albicans and by the injection in incomplete freund's adjuvant of nonviable coccidioides immitis spherule fragments. other pathogenic or nonpathogenic fungi produced little or no protection. salmonell ...196314066415
experimental salmonellosis. iii. new toxic fraction (l) obtained from salmonella enteritidis and its immunological properties.kawakami, masaya (gunma university, maebashi, japan), nobutaka osawa, and susumu mitsuhashi. experimental salmonellosis. iii. new toxic fraction (l) obtained from salmonella enteritidis and its immunological properties. j. bacteriol. 86:872-879. 1963.-a method is described for the purification of the heat-labile toxins of a fully virulent strain, 116-54, of salmonella enteritidis by ion-exchange chromatography. one component of the heat-labile toxin (l) was homogeneous, as evidenced by the resul ...196314066488
[an outbreak of a toxinfection caused by salmonella enteritidis moscow]. 196314117929
preparation and properties of an aluminum citrate-endotoxin complex from salmonella enteritidis. 196313960883
on the chemical, bacteriological and pharmacological research in culture fish medium of salmonella enteritidis. 196314218690
[action of optical antipodes of serine on the growth of salmonella enteritidis typhimurium and of proteus vulgaris x19]. 196313938446
resistance of the mouse's intestinal tract to experimental salmonella infection. i. factors which interfere with the initiation of infection by oral inoculation.multiplication of salmonella enteritidis was inhibited in vitro by buffered suspensions of fecal material freshly removed from the large intestine of normal mice. most effective was material obtained from cecum and transverse colon. inhibitory activity was not impaired by sterilization by heat or filtration. from such materials were isolated acetic and butyric acids in concentrations which inhibited salmonella in vitro. the degree of inhibitory activity of suspensions of colon content and of mix ...196414247721
resistance of the mouse's intestinal tract to experimental salmonella infection. ii. factors responsible for its loss following streptomycin treatment.determinations of ph, eh, and concentrations of acetic, butyric and lactic acids were made on the content of cecum and transverse colon of groups of mice killed 1, 3, and 5 days after oral administration of 50 mg streptomycin. control observations on untreated mice are reported in the preceding communication. heat-killed supenatants of suspensions of bowel content were tested in vitro for their ability to inhibit multiplication of our standard streptomycin-resistant strain of salmonella enteriti ...196414247722
extraction and purification of endotoxin from enterobacteriaceae: a comparison of selected methods and sources.fukushi, k. (national institute of allergy and infectious diseases, rocky mountain laboratory, hamilton, mont.), r. l. anacker, w. t. haskins, m. landy, k. c. milner, and e. ribi. extraction and purification of endotoxin from enterobacteriaceae: a comparison of selected methods and sources. j. bacteriol. 87:391-400. 1964.-endotoxins containing only 0.2% n (accounted for by amino sugars) and 2% ester- and amide-linked fatty acids (calculated as palmitic acid) were prepared from salmonella enterit ...196414151062
[septicemia caused by salmonella enteritidis]. 196414181747
[action of isoleucine optical antipodes on the development of a salmonella enteritidis typhimurium strain accustomed to flabelline]. 196414186907
the ability of amoeba proteus to kill salmonella enteritidis introduced by micro-injection, and the influence of opsonins on intracellular killing. 196414208693
production of antibody in mammary gland of pregnant, non-lactating and lactating cows, evoked by polyvalent antigen with reference to dosage and frequency of immunization.sixteen cows were used in a series of experiments to test dose, route and frequency responses in the production of milk and serum agglutinins to a spectrum of 9 proven bovine pathogens. the bacterial species were: pasteurella multocida (2 isolates), escherichia coli, staphylococcus aureus, staphylococcus albus, streptococcus sp., corynebacterium sp., salmonella enteriditis, and aerobacter aerogenes. primary immunizations were made either through the teat canal or intramuscularly. "booster" injec ...196417649521
experimental salmonellosis. iv. lipid content of toxin l obtained from salmonella enteritidis.kawakami, masaya (gunma university, maebashi, japan), and susumu mitsuhashi. experimental salmonellosis. iv. lipid content of toxin l obtained from salmonella enteritidis. j. bacteriol. 89:193-197. 1965.-an improved method is described for the chromatographic purification of toxin l from virulent salmonella enteritidis. toxin l is heat-labile, and its toxicity is reduced by trypsin and by phospholipase a treatment. chemical studies of chromatographically and ultracentrifugally homogeneous toxin ...196514255662
involvement of thymus in immune response of rabbits to somatic polysaccharides of gram-negative bacteria.plaque-forming cells elaborating antibody specific for salmonella enteritidis somatic antigen have been demonstrated in the thymus of rabbits 5 days after a single systemic injection of a minute amount of this bacterial polysaccharide. a marked decrease in organ weight and loss of thymic cellularity was also seen, and was most pronounced at the time when antibody-forming cells made their appearance.196514260379
[live vaccine immunization in experimental typhoid with a streptomycin dependent strain of salmonella enteritidis]. 196514320564
[cytophilic immunity with special reference to salmonella enteritidis sensitivity experiments in mice]. 196514329557
experimental salmonellosis vi. in vitro transfer of cellular immunity of mouse mononuclear phagocytes.saito, kazuko (gunma university, maebashi, japan), and susumu mitsuhashi. experimental salmonellosis. vi. in vitro transfer of cellular immunity of mouse mononuclear phagocytes. j. bacteriol. 90:629-634. 1965.-a culture medium of the mononuclear phagocytes (monocytes) of mice immunized with live vaccine of salmonella enteritidis contains the transfer agent (ta) of cellular immunity from immune to non-immune monocytes. the ta is of ribonucleic acid nature, is nondialyzable through cellophane, and ...196516562059
humoral and cellular aspects of the immune response to the somatic antigen of salmonella enteritidis.a study was made of the cellular and humoral aspects of the immune response of the rabbit to the somatic polysaccharide of salmonella enteritidis. the response to a single intravenous injection was characterized by the appearance of elevated titers of bactericidal antibody between 2 and 3 days later. the maximum titer was dose-dependent and occurred between 5 and 7 days, thereafter declining rapidly during the first month. the significant stabilized levels which then persisted for at least 1 yea ...19655839282
experimental salmonellosis. vii. in vitro transfer of cellular immunity by ribosomal fraction of mouse mononuclear phagocytes.sato, ichiei (gunma university, maebashi, japan), and susumu mitsuhashi. experimental salmonellosis. vii. in vitro transfer of cellular immunity by ribosomal fraction of mouse mononuclear phagocytes. j. bacteriol. 90:1194-1199. 1965.-the mononuclear phagocytes (termed monocytes) of mice hyperimmunized with live vaccine of salmonella enteritidis inhibited the intracellular growth of virulent strain 116-54 of s. enteritidis. also, the monocytes withstood the degeneration of cells caused by the pha ...19655848324
[hospital infections caused by salmonella enteritidis in children]. 19655850620
[on the possibility of dissemination of salmonella enteritidis infections through the respiratory route]. 19655882918
[salmonella enteriditis infection in a childhood environment]. 19655882922
[infection due to salmonella enteritidis gaertneri in infants and small children under 3 years of age according to personal observations]. 19655883579
[time-lapse study of infection in the peritoneal cavity of mice immunized with the particulate fraction from salmonella enteritidis cells]. 19655893619
infection of salmonella pullorum, salmonella newington or salmonella enteritidis in laboratory rats by oral inoculation. 19655294502
frequency of occurrence of native hapten among enterobacterial species.anacker, r. l. (rocky mountain laboratory, hamilton, mont.), w. d. bickel, w. t. haskins, k. c. milner, e. ribi, and j. a. rudbach. frequency of occurrence of native hapten among enterobacterial species. j. bacteriol. 91:1427-1433. 1966.-smooth cultures of representative enterobacteriaceae were screened for the presence of native hapten, a substance previously extracted with trichloroacetic acid from the protoplasmic fraction of one strain each of escherichia coli o111:b4 and o113. trichloroacet ...19665326701
effects of immunization of guinea pigs lacking bactericidal antibody against salmonella enteritidis. 19665331879
ultrastructural changes in mesenteric lymph nodes of mice infected with salmonella enteritidis. 19665908855
[epidemiologic observations on the infection of infants by salmonella enteriditis on the basis of data of the clinical hospital nr. 4 in lodz]. 19665912982
[clinical observations in the course of infections caused by salmonella enteriditis in children]. 19665913437
infection-immunity in experimental salmonellosis.salmonella enteritidis is highly virulent for the mouse causing an infection resembling mouse typhoid. survivors of the infection are completely resistant to reinfection and eliminate a large challenge dose of virulent organisms within 72 hr. the antigenically related salmonella gallinarum was almost avirulent for the mouse but animals vaccinated with this organism were equally capable of eliminating a lethal dose of virulent s. enteritidis. living salmonella pullorum, on the other hand, was qui ...19665922286
heat-labile antigens of salmonella enteritidis. ii. mouse-protection studies.collins, f. m. (university of adelaide, adelaide, south australia), and margaret milne. heat-labile antigens of salmonella enteritidis. ii. mouse-protection studies. j. bacteriol. 92:549-557. 1966.-a number of extracts prepared from a virulent and an avirulent strain of salmonella enteritidis were used to immunize mice. living and alcohol-killed whole-cell vaccines were also used to compare the relative protective value of the various preparations. all mice were challenged intravenously with 100 ...19665922532
characterization of "clearance" factor and "cell-bound" antibody in experimental typhoid.daizo, ushiba (keio university school of medicine, tokyo, japan), taiji nakae, takehisa akiyama, and yoshio kishimoto. characterization of "clearance" factor and "cell-bound" antibody in experimental typhoid. j. bacteriol. 91:1705-1712. 1966.-the "clearance" factor produced in the serum of rabbits immunized with a killed vaccine of an s-type virulent strain of salmonella enteritidis was identified as o agglutinin and characterized immunochemically as a class of macroglobulin with a sedimentation ...19665937233
stimulation of nonspecific resistance to infection by a crude cell wall preparation from mycobacterium phlei.fox, alfred e. (warner-lambert research institute, morris plains, n.j.), george l. evans, frank j. turner, benjamin s. schwartz, and ansel blaustein. stimulation of nonspecific resistance to infection by a crude cell wall preparation from myocobacterium phlei. j. bacteriol. 92:1-5. 1966.-exposure of large quantities of viable mycobacterium phlei to attrition in a colloid mill resulted in 90 to 95% disruption of the organisms. isolation of the crude cell wall preparation was accomplished by centr ...19665941276
[properties of strains of salmonella enteritidis isolated in poland. 1. sensitivity to some antibiotics and nitrofurans]. 19665957290
experimental salmonellosis. vii. comparison of the immunizing effect of live vaccine and materials extracted from salmonella enteritidis.kawakami, masaya (gunma university, maebashi, japan), nobutaka osawa, and susumu mitsuhashi. experimental salmonellosis. vii. comparison of the immunizing effect of live vaccine and materials extracted from salmonella enteritidis. j. bacteriol. 92:1585-1589. 1966.-attempts were made to isolate the factors of live vaccine which immunize against salmonella enteritidis infection in mice. some effective substances were found in cellular extracts of this organism when those extracts were prepared by ...19665958100
cellular immunity with special reference to monocytes of mice immunized with live vaccine of salmonella enteritidis. 19665969551
[non-specific resistance to the infection with salmonella enteritidis induced in mice vaccinated with bcg. (ii)]. 19666010438
[non-specific resistance of the bcg vaccinated mice to the infection with salmonella enteritidis (i)]. 19666010589
heat-labile antigens of salmonella enteritidis. i. extraction of antigens.milne, margaret (university of adelaide, adelaide, australia), and f. m. collins. heat-labile antigens of salmonella enteritidis. i. extraction of antigens. j. bacteriol. 92:543-548. 1966.-salmonella enteritidis strains of high and low mouse virulence were grown in continuous culture. cell walls were obtained from both strains by sonic disruption, and the washed walls were extracted at 4 c with sodium dodecyl sulfate or sodium deoxycholate. the extracts were eluted with a saline gradient from a ...19664958772
the microbiological and epidemiological properties of infections caused by salmonella enteritidis. 19665219025
isolation of a soluble resistance-enhancing factor from mycobacterium phlei.fox, alfred e. (warner-lambert research institute, morris plains, n.j.), joachim anschel, george l. evans, raam r. mohan, and benjamin s. schwartz. isolation of a soluble resistance-enhancing factor from mycobacterium phlei. j. bacteriol. 92:285-290. 1966.-extraction of a crude cell wall preparation from mycobacterium phlei with 20% urea yielded a fraction which induced a state of enhanced resistance to microbial challenge. the resulting soluble extract, after removal of the urea, represented a ...196616562108
quantitative analyses of certain enteric bacteria and bacterial extracts: i. standardization and sonic disruption of eight enteric bacterial species, each at five population levels.standardized individual preparations of five population levels of eight enteric organisms [escherichia coli (o4:h3), e. coli (o111:b4:h12), salmonella enteritidis, s. paratyphi b, s. typhimurium, shigella boydii, s. dysenteriae, and s. sonnei) were prepared. dry weights, calculated mean cell weight, and nitrogen content of bacterial suspensions before, and of supernatant fluids after, ultrasonic disruption are tabulated. percentages of disruption, estimated from nitrogen concentration ratios of ...196716349752
catecholamine excretion and bronchial response to methacholine after salmonella enteriditis endotoxin in a normal and an asthmatic subject. 19675228669
[on the heterogeneity of the population of salmonella enteritidis with regard to decarboxylase acitvity]. 19675613972
[elimination of salmonella enteritidis infection in a breeding stock of rats. brief report]. 19675629067
the direct reaction between salmonella enteritidis endotoxin and antibody. measurement of 7s and 19s antibody in normal, tolerant and immune sera. 19676024982
experimental salmonellosis. 8. postinfective immunity and its significance for conferring cellular immunity.in the process of live-vaccine immunization of salmonella enteritidis infection in mice, the relation between the number of bacteria in the organs of mice and their protecting effect was studied. treatment with antibiotics was used to control the number of immunizing bacteria in the tissues. mice, which were infected with 10(-5) mg (1,000 mouse mld) of virulent s. enteritidis and treated with kanamycin simultaneously, acquired high antilethal resistance against infection with the same organisms. ...19676025441
response of wild rats (rattus norvegicus) bred in captivity to oral inoculation with salmonella pullorum, salmonella newington, and salmonella enteritidis. 19676027435
report of the bacteriological findings following an epidemic of salmonella enteritidis in a small ship. 19676046983
experimental salmonellosis. x. cellular immunity and its antibody in mouse mononuclear phagocytes.a cell-associated antibody was detected in the peritoneal mononuclear phagocytes (referred to as monocytes) of mice hyperimmunized with live vaccine of salmonella enteritidis, by use of immune transfer and immune adherence hemagglutination techniques. the cellular antibody inhibited the growth of a virulent strain of s. enteritidis with the aid of complement and lysozyme on nutrient agar plates. this type of bactericidal antibody could not be detected in the monocytes of mice immunized with kill ...19676051362
[hospital infections with salmonella enteritidis bacilli]. 19676056129
[analysis of complications in the course of salmonellosis due to salmonella enteriditis gärtneri]. 19676059122
[cases of illness caused by salmonella enteritidis in poland in 1957-1965]. 19676069775
[significance of the membrane component and ribosomes in the immunization with particulate fraction of salmonella enteritidis]. 19676070800
in vitro assay of endotoxin by the inhibition of macrophage migration.a quantitative in vitro technique was used to compare the ability of different endotoxins to inhibit the migration of macrophages from explants of rabbit spleen cultured in a coagulated plasma medium. the order of potency was different from that observed in chick embryo assays, and in assays with mice, of the same endotoxins. in general, however, the sensitivity of the macrophage inhibition test was comparable to that of other bioassay methods. a highly purified endotoxin from salmonella enterit ...19675335889
failure of bacterial endotoxin to produce the generalized shwartzman reaction in the syrian hamster.the ability of bacterial endotoxin to produce the generalized shwartzman reaction (gsr) in pregnant and nonpregnant hamsters was investigated. endotoxins prepared from escherichia coli o127:b8, salmonella enteritidis, and s. typhosa 0-901 did not produce the gsr in nonpregnant hamsters. injection of lead acetate did not make the hamsters susceptible to the gsr producing effects of endotoxin. endotoxin administered to hamsters on either or both the 14th and 15th day of the 16-day gestation period ...19675340677
[epidemiological evaluation of infections due to salmonella enteriditis in wroclaw in 1964-1965]. 19685654451
[properties of salmonella enteriditis strains isolated in poland. ii. biochemical differentiation]. 19685663152
[differentiation of strains of salmonella enteriditis with bacteriophages]. 19685670157
the adherence to salmonella enteritidis of igg, igm and b1c-globulins from guinea-pig serum. 19685673288
salmonella enteritidis from porcine meningitis. a case report. 19685689442
the role of serum lipase in the degradation of salmonella enteritidis endotoxin. 19685691259
natural antibodies to salmonella enteritidis endotoxin in maternal and cord sera and in sera of patients with immunologic deficiency diseases. 19685693658
[properties of salmonella enteriditis strains isolated in poland]. 19685702418
[contribution to the treatment of salmonella enteriditis infections in infants]. 19685709301
cross-protection against salmonella enteritidis infection in mice.mice were vaccinated with six strains of salmonella and two strains of escherichia coli, as well as with pseudomonas aeruginosa, proteus vulgaris, and serratia marcescens. the amount of in vivo growth of each organism was followed by viable counting techniques on organ homogenates. the vaccinated mice, along with unvaccinated controls, were challenged intravenously with 1,000 ld(50) of a streptomycin-resistant strain of salmonella enteritidis. the ability of the vaccine to protect the mice again ...19684967195
[sensitivity of some strains of salmonella enteriditis to disinfecting agents]. 19684875959
recall of immunity in mice vaccinated with salmonella enteritidis or salmonella typhimurium.mice were immunized with living salmonella enteritidis or s. typhimurium and then were reinfected 8, 30, 60, and 150 days later with streptomycin-resistant strains of s. enteritidis, s. typhimurium, or a mixture of the two organisms. the level of resistance at the time of challenge and the rate at which resistance was recalled in late convalescence was determined by daily liver and spleen counts of the challenge population. an immediately effective specific antibacterial immunity was maintained ...19684876124
characteristics of salmonella enteritidis strains isolated in poland. 19695770243
effect of specific immune mouse serum on the growth of salmonella enteritidis in nonvaccinated mice challenged by various routes.salmonella enteritidis was injected intravenously, intraperitoneally, or subcutaneously into specific pathogen-free mice. the number of organisms in the blood, liver, spleen, peritoneal cavity, and draining inguinal lymph node was determined by daily enumeration. opsonization of the organism with hyperimmune serum increased the rate of phagocytosis, resulting in rapid blood clearance together with an alteration in the relative numbers of organisms accumulating in the liver and spleen. serum trea ...19695773020
effect of specific immune mouse serum on the growth of salmonella enteritidis in mice preimmunized with living or ethyl alcohol-killed vaccines.the effect of prior opsonization of virulent salmonella enteritidis on the growth of this organism in blood, liver, spleen, peritoneal cavity, and inguinal lymph node of specific pathogen-free mice prevaccinated with ethyl alcohol-killed s. enteritidis or living s. gallinarum was determined by daily enumeration. both the vaccines and the challenge inocula were injected by the intravenous, intraperitoneal, or subcutaneous routes to determine the effect of variations in the vaccinating procedure o ...19695773021
[cerebral abscess during salmonella enteriditis infection in a 8-month-old infant]. 19695776126
distribution and degradation of sublethal doses of i-125 labeled endotoxin from salmonella enteritidis in mice. 19695787129
two additional salmonella serotypes. salmonella enteritidis ser 58:a:- and salmonella enteritidis ser 44:z36, z38:-.the antigenic compositions of two additional salmonella serotypes isolated from the feces of man were determined to be 58:a:- and 44:z(36), z(38)-.19695797945
new salmonella serotype: salmonella enteritidis ser. ordonez.the antigenic formula of a new serotype, salmonella enteritidis serotype ordonez, was characterized as (1),13,23,37:y:l,w.19695807159
salmonella enteritidis isolated from a focus of chronic osteomyelitis in a fatal case of agranulocytosis. 19695823628
a longitudinal study of serum alpha-1-antitrypsin, alpha-2-macroglobulin, transferrin, immunoglobulins igg, iga and igm, and h- and o-agglutinin titers in children following infection with salmonella enteritidis. 19704983358
[pathogenic enterobacteria in grand kabylia (ain el hammam region)]. 19704950338
[salmonella in algeria: the salmonella of northern area of the sahara]. 19704950342
[water-born epidemic caused by salmonella enteritidis]. 19705200778
undescribed serotype of salmonella: salmonella enteritidis ser. lovelace.a new serotype of salmonella is described. culture 1505-68, serotype 13,22,36:l, v:1,5, was recovered from the stool of a female patient and designated salmonella enteritidis ser. lovelace.19705415212
toxigenesis and infection of mice by salmonella enteritidis. 19705419129
[the antigenic activity of a streptomycin dependent mutant of salmonella enteritidis defective in lipopolysaccharide structure]. 19705424244
[clinical observations on the course of salmonella enteritidis infections in children]. 19705431382
salmonella enteritidis serotype 50-1,2,3: z4, z24:-.characteristics of a new salmonella serotype, subgenus iv, are reported. culture 5534-68 was recovered from the intestinal tract of anolis biporcatus, an arboreal lizard found in deep forest tracts in panama province, republic of panama. the antigenic composition of this new serotype was found to be 50(1, 2, 3):z(4), z(24):-.19705463184
[subdural empyema due to salmonella enteritidis in an 1-year-old child]. 19705463974
[observations and studies on the infectivity of salmonella enteritidis var. danysz]. 19705484783
[preliminary reports on the spread of infections caused by salmonella enteritidis]. 19705506802
action of bacterial growth on the sarcoplasmic and urea-soluble proteins from muscle. i. effects of clostridium perfringens, salmonella enteritidis, achromobacter liquefaciens, streptococcus faecalis, and kurthia zopfi.comparisons of the starch-gel patterns of uninoculated aseptic control samples from rabbit and pig muscle with similar samples inoculated and incubated with clostridium perfringens, salmonella enteritidis, achromobacter liquefaciens, and kurthia zopfii were made. results indicated that c. perfringens caused extensive alteration in the proteins or enzymes, or both, of the sarcoplasmic fraction of porcine muscle, whereas s. enteritidis and s. faecalis caused complete breakdown of only myoglobin. n ...19704318570
some structural and biological properties of brucella endotoxin.hot phenol-water extraction of smooth brucella abortus and b. melitensis cells yielded a toxic fraction which was recovered from the phenol phase (fraction 5). chemically, fractions 5 from both brucella species were lipid-carbohydrate-protein-2 keto-3-deoxyoctulosonic acid complexes which were stable to heat and resistant to pronase digestion. electron micrographs of the brucella toxins were morphologically indistinguishable from those of enterobacterial endotoxins. biologically, brucella toxins ...197016557710
immunity to enteric infection in mice.specific pathogen-free cd-1 mice infected orally with sublethal doses (10(4) to 10(6) viable organisms) of salmonella enteritidis rapidly developed extensive bacterial populations in the liver, spleen, and mesenteric lymph nodes. although the pathogen did not multiply extensively in the gut, the infection persisted in the intestine at between 10(4) and 10(5) viable organisms throughout the experiment. s. gallinarum was less invasive than s. enteritidis when given by mouth; s. pullorum failed to ...197016557723
oral immunization against experimental salmonellosis i. development of temperature-sensitive mutant vaccines.mutant strains of salmonella enteritidis were selected for their inability to proliferate at 37 c; when exposed to this temperature, these organisms formed tangled masses of long filaments in liquid media, presumably as a result of their inability to form cross septa. the mutants were also incapable of synthesizing flagella protein. a study of the biological charateristics of the mutants indicated that in most respects they resembled the parent strain of s. enteritidis; however, they were avirul ...197016557726
subcellular localization of salmonella enteritidis endotoxin in liver and spleen of mice and rats.salmonella enteritidis(14)c-endotoxin was recovered predominantly from the nuclear and mitochondrial subcellular fractions of livers and spleens of mice and rats, 3.5 hr and 3 days after intravenous administration. of the recovered radioactivity, 10 to 20% was present in the liver mitochondrial fraction as high-molecular-weight, biologically active material, suggesting the presence of intact endotoxin. autoradiographic studies demonstrated nuclear and cytoplasmic labeling in the liver and at lea ...197016557755
oral immunization in experimental salmonellosis ii. characteristics of the immune response to temperature-sensitive mutants given by oral and parenteral routes.a temperature-sensitive mutant of salmonella enteritidis, selected because of its inability to proliferate normally at 37 c, has been used as a living vaccine in mice. when given parenterally or orally, it confers a high degree of resistance against otherwise lethal s. enteritidis infections given intraperitoneally or by mouth. in contrast to most other effective living salmonella vaccines, the temperature-sensitive mutant survives for only short periods in mouse tissues. although the vaccine pr ...197016557818
oral immunization in experimental salmonellosis iii. behavior of virulent and temperature-sensitive mutant strains in the intestinal tissues of rats.infection of rats via a peyer's patch has been used as a means of studying the behavior of salmonella enteritidis in intestinal tissues. the course of infection in the peyer's patch and draining mesenteric lymph node is characterized by multiplication of the organism over a period of 4 days followed by a gradual decline in numbers; the organism also passes to the liver and spleen and may be isolated from these organs as well as the intestinal tissues for at least 4 weeks. temperature-sensitive m ...197016557819
enhancement of bacterial infections in mice by newcastle disease virus.this report describes an attempt to define the factors which incite secondary bacterial pneumonias. groups of mice were given bacteria intraperitoneally and, at various intervals, newcastle disease virus intravenously. there was an increase in the number of deaths and in the rates of death in these groups, when compared with a control group which was given only bacteria. these results were obtained with streptococcus pneumoniae (diplococcus pneumoniae), pseudomonas aeruginosa, and salmonella ent ...197116558000
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