Publications

presence of human and animal viruses in surface waters in vojvodina province of serbia.	for the first time in serbia, a small surveillance study was conducted in order to estimate the presence and frequency of occurrence of selected human [adenoviruses (hadv), noroviruses, (nov gi, nov gii) and hepatitis a virus (hav)], animal [porcine adenovirus (padv) and bovine polyomavirus (bpyv)] and zoonotic [hepatitis e virus (hev)] viruses in selected surface waters. in total, 60 surface water samples were collected in two sampling occasions at 30 locations, with each sampling time being se ...	2015	25687987
detection of hepatitis e virus in pork liver sausages.	hepatitis e infection is regarded as an emerging public-health concern. the disease is normally self-limiting (mortality rate 1%), but chronic infections have recently been observed in transplanted patients. the etiological agent hev is a small rna virus infecting both humans and animals. in humans, the disease may be food-borne and pig is a main reservoir for zoonotic strains. in the present study, we evaluated the presence of hev and swine fecal cross-contamination in pork liver sausages sold ...	2015	25462920
genes indicative of zoonotic and swine pathogens are persistent in stream water and sediment following a swine manure spill.	manure spills into streams are relatively frequent, but no studies have characterized stream contamination with zoonotic and veterinary pathogens, or fecal chemicals, following a spill. we tested stream water and sediment over 25 days and downstream for 7.6 km for the following: fecal indicator bacteria (fib), the fecal indicator chemicals cholesterol and coprostanol, 20 genes for zoonotic and swine-specific bacterial pathogens by presence/absence pcr for viable cells, one swine-specific escheri ...	2015	25769829
incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: implications for immune-mediated cancer therapy.	one strategy in cancer immunotherapy is to capitalize on the key immunoregulatory and antigen presenting capabilities of dendritic cells (dcs). this approach is dependent on efficient delivery of tumor specific antigens to dcs, which subsequently induce an anti-tumor t-cell mediated immune response. human adenovirus serotype 5 (hadv5) has been used in human studies for gene delivery, but has limited infection in dcs, which lack the proper receptors. addition of the porcine fiber knob (pk) from p ...	2015	25933160
a novel and simple method for rapid generation of recombinant porcine adenoviral vectors for transgene expression.	many human (different serotypes) and nonhuman adenovirus vectors are being used for gene delivery. however, the current system for isolating recombinant adenoviral vectors is either time-consuming or expensive, especially for the generation of recombinant non-human adenoviral vectors. we herein report a new and simple cloning approach for the rapid generation of a porcine adenovirus (padv-3) vector which shows promise for gene transfer to human cells and evasion of human adenovirus type 5 (hadv- ...	2015	26011074
propidium monoazide coupled with pcr predicts infectivity of enteric viruses in swine manure and biofertilized soil.	the use of propidium monoazide (pma) coupled with real-time pcr (rt-qpcr or qpcr for rna or dna viruses, respectively) was assessed to discriminate infectious enteric viruses in swine raw manure, swine effluent from anaerobic biodigester (ab) and biofertilized soils. those samples were spiked either with infectious and heat-inactivated human adenovirus-2 (hadv-2) or mengovirus (vmc0), and pma-qpcr/rt-qpcr allowed discriminating inactivated viruses from the infective particles, with significant r ...	2016	26742766
f-coliphages, porcine adenovirus and porcine teschovirus as potential indicator viruses of fecal contamination for pork carcass processing.	there are concerns about the zoonotic transmission of viruses through undercooked pork products. there is a lack of information on suitable indicator viruses for fecal contamination with pathogenic enteric viruses in the meat processing chain. the study compared the incidence and levels of contamination of hog carcasses with f-coliphages, porcine teschovirus (ptv), and porcine adenovirus (padv) at different stages of the dressing process to assess their potential as indicator viruses of fecal co ...	2017	27810445
first detection of enteric adenoviruses genotype 41 in recreation spring areas of taiwan.	human adenoviruses (hadvs) are dna viruses found in recreational water, such as water parks and swimming pools. human adenovirus 41 (hadv-41) is the most common serotype detected and is a leading cause of acute diarrheal disease. the focus of this study is to determine the prevalence of hadvs in hot springs. of 57 samples collected from four different geological sites, 16 samples have shown evidence of hadvs (28.1%). hadv-41 and porcine adenovirus 5 (padv-5) were the two types isolated, with a g ...	2017	28639027