Publications

bacterial pituitary abscess: an unusual cause of panhypopituitarism.	to describe a case of primary bacterial pituitary abscess manifesting as hypopituitarism.	2002	15251832
minocycline effectively reduces acid producted by propionibacterium granulosum.	we studied the effects of minocycline on propionibacterium granulosum. p. granulosum lipase activity was detected from acne lesions. production of propionic and butyric acids by p. granulosum was well suppressed by all tested media with added minocycline; the higher the concentration of minocycline in the medium, the less of these acids was produced. it appeared that the decrease in these acids due to minocycline was greater in p. granulosum than in p. acnes. although the influence of p. granulo ...	2002	11837569
diagnosis of pelvic actinomycosis by 16s ribosomal rna gene sequencing and its clinical significance.	traditional ways of identification of anaerobic gram-positive non-sporulating bacilli by isolation of the organism and studying it phenotypically by elucidation of its morphologic and biochemical characteristics and metabolic end products are associated with a need for special equipment and expertise, and strains that are "unidentified" because of ambiguous biochemical profiles. in this study, an anaerobic gram-positive non-sporulating bacterium was isolated from the intrauterine contraceptive d ...	2002	12088617
assessment of mycobacterial, propionibacterial, and human herpesvirus 8 dna in tissues of greek patients with sarcoidosis.	the causes of sarcoidosis are unknown. in this study, we report the presence of mycobacterium tuberculosis complex and propionibacterium granulosum dna in a significant proportion of greek patients with sarcoidosis. human herpesvirus 8 dna was not detected in sarcoid tissues from greek patients. our findings are discussed.	2002	12149380
quantitative analysis of mycobacterial and propionibacterial dna in lymph nodes of japanese and european patients with sarcoidosis.	the cause(s) of sarcoidosis is unknown. mycobacterium spp. are suspected in europe and propionibacterium spp. are suspected in japan. the present international collaboration evaluated the possible etiological links between sarcoidosis and the suspected bacterial species. formalin-fixed and paraffin-embedded sections of biopsy samples of lymph nodes, one from each of 108 patients with sarcoidosis and 65 patients with tuberculosis, together with 86 control samples, were collected from two institut ...	2002	11773116
multiple bacteria in aortic aneurysms.	the purpose of the present study was to reexamine the possibility that bacteria, particularly anaerobes, are present in aortic aneurysms.	2003	14681645
streptococcal cell wall induced arthritis: leukocyte activation in extra-articular lymphoid tissue.	rheumatoid arthritis (ra) is a common systemic inflammatory disease thought to be t-helper-1 cell driven, though current controversy involves the relative role of t cells versus other leukocytes. thus, there is a need for better understanding of the role of various leukocytes and their subsets in ra. using the streptococcal cell wall (scw) induced arthritis model, we examined leukocytes isolated from peripheral blood, spleen, and lymph nodes using monoclonal antibodies directed against lineage s ...	2003	12797545
unusual anaerobic bacteria in keratitis after laser in situ keratomileusis: diagnosis using molecular biology methods.	laser in situ keratomileusis (lasik) was performed in the left eye of a 57-year-old man for residual ametropia after phacoemulsification. the patient was given topical tobramycin and a corticosteroid for 1 week postoperatively. fifteen days later, he developed 3 corneal infiltrates beneath the flap with a gas bubble, suggesting an anaerobic infection. tobramycin and ofloxacin were administered every 2 hours, but the condition worsened. corneal scrapings were taken from beneath the flap for micro ...	2004	15313309
in vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against propionibacterium sp.	honokiol and magnolol, two major phenolic constituents of magnolia sp., have been known to exhibit antibacterial activities. however, until now, their antibacterial activity against propionibacterium sp. has not been reported. to this end, the antibacterial activities of honokiol and magnolol were detected using the disk diffusion method and a two-fold serial dilution assay. honokiol and magnolol showed strong antibacterial activities against both propionibacterium acnes and propionibacterium gr ...	2004	15288590
activity of nadifloxacin (opc-7251) and seven other antimicrobial agents against aerobic and anaerobic gram-positive bacteria isolated from bacterial skin infections.	the in vitro activity of nadifloxacin (opc-7251), a novel topical fluoroquinolone, was assessed and compared with those of ofloxacin, oxacillin, flucloxacillin, cefotiam, erythromycin, clindamycin, and gentamicin against 144 gram-positive bacteria: 28 staphylococcus aureus, 10 streptococcus spp., 68 coagulase-negative staphylococci (cns), 36 propionibacterium acnes, and 2 propionibacterium granulosum strains. all strains originated from bacterial-infected skin disease and were isolated from pati ...	2004	15452398
characterisation of cryptic plasmid ppg01 from propionibacterium granulosum, the first plasmid to be isolated from a member of the cutaneous propionibacteria.	a cryptic plasmid, ppg01 (3539bp), was isolated from propionibacterium granulosum and sequenced. analysis of open reading frames (orfs) predicted ppg01 to encode three proteins. the largest protein (447 amino acids) showed homology to the ftsk/spoiiie family of proteins involved in chromosome partitioning during cell division and conjugal transfer of dna. a second protein of 433 amino acids showed homology to plasmid replication proteins that mediate replication by the rolling circle mechanism. ...	2007	17360038
quantitative analysis of propionibacterial dna in bronchoalveolar lavage cells from patients with sarcoidosis.	the causes of sarcoidosis are still unknown. propionibacterial subspieces are thought to be one of the most likely sources of antigens. here we attempted to measure the amount of propionibacterial dna in bronchoalveolar lavage (bal) cell samples from patients with sarcoidosis and other pulmonary diseases.	2008	19070256
microbial quality of equine frozen semen.	bacteriological surveillance is little applied in management of equine frozen semen but it is quite important to verify the microbial contamination in order to find out the chance of transmission of pathology to the mare in ai. authors describe a qualitative and quantitative analysis for bacterial contamination on long time (3-17 years) equine frozen semen stored in liquid nitrogen. the semen checked, produced in italy and in another europe country, was cryopreserved in liquid nitrogen inside se ...	2009	19144477
effect of immunostimulation by detoxified e. coli lipopolysaccharide combined with inactivated propionibacterium granulosum cells on porcine immunity.	the aim of this experiment was to evaluate the immunomodulating activities of inactivated propionibacterium granulosum cell walls and e. coli lipopolysaccharide (pg/lps) on porcine immunity. piglets were intramuscularly administered pg/lps (1 ml/10 kg body weight) once or twice. the function of natural killer cells, lymphocytes and neutrophils and the adjuvant effect on antibody induction by attenuated classical swine fever virus (csfv) and inactivated mycoplasma hyopneumoniae vaccination were e ...	2009	19652476
identification, typing and characterisation of propionibacterium strains from healthy mucosa of the human stomach.	forty two propionibacterium isolates were recovered from biopsy samples of the gastric mucosa of eight out of 12 healthy people. of these, 41 were identified as belonging to propionibacterium acnes; the remaining isolate was identified as belonging to propionibacterium granulosum. repetitive extragenic palindromic (rep)-pcr typing suggested that up to four strains might be present in the mucosa of the same individual. sequence analysis of either reca, tly or camp5 genes of p. acnes isolates reve ...	2011	21329995
nonsurgical management of complicated splenic rupture in infectious mononucleosis.	we report on a 35-year-old man who presented to the emergency department with acute abdominal pain, postural hypotension, and tachycardia after having been diagnosed with epstein-barr virus infection 1 week before. abdominal ultrasound and computed tomography revealed splenic rupture, and the patient underwent successful proximal angiographic embolization of the splenic artery. the course was complicated by painful splenic necrosis and respiratory insufficiency due to bilateral pleural effusions ...	2013	23602745
arthroplasty infection by priopionibacterium granulosum treated with reimplantation despite ongoing purulent-appearing fluid collection.	we present the first case of infection in a native or prosthetic joint by propionibacterium granulosum in which a patient developed symptoms of prosthetic hip infection 5 years after primary surgery. the patient required multiple operative debridements to eradicate the infection and was successfully reimplanted despite an ongoing purulent-appearing, although sterile, fluid collection at the time of reimplantation. there is no clinical or laboratory evidence of infection at 3 years post-reimplant ...	2013	22552222
comparative genomics reveals distinct host-interacting traits of three major human-associated propionibacteria.	propionibacteria are part of the human microbiota. many studies have addressed the predominant colonizer of sebaceous follicles of the skin, propionibacterium acnes, and investigated its association with the skin disorder acne vulgaris, and lately with prostate cancer. much less is known about two other propionibacterial species frequently found on human tissue sites, propionibacterium granulosum and propionibacterium avidum. here we analyzed two and three genomes of p. granulosum and p. avidum, ...	2013	24053623
simultaneous visualization of propionibacterium acnes and propionibacterium granulosum with immunofluorescence and fluorescence in situ hybridization.	propionibacterium acnes (p. acnes) and propionibacterium granulosum (p. granulosum) are common skin colonizers that are implicated as possible contributing factors in acne vulgaris development. we have established direct visualization tools for the simultaneous detection of these closely related species with immunofluorescence assay and fluorescence in situ hybridization (fish). as proof of principle, we were able to distinguish p. acnes and p. granulosum bacteria in multi-species populations in ...	2013	23896347
microbiology of hidradenitis suppurativa (acne inversa): a histological study of 27 patients.	hidradenitis suppurativa (acne inverse) (hs) is a chronic skin disease primarily affecting hair follicles. the aetiology of hs is unknown, but infection is believed to play some role. this retrospective study investigated the microbial colonization directly in skin appendices in hs skin samples. archival samples from 27 patients with hs were screened by immunofluorescence labelling with monoclonal and polyclonal antibodies against gram-positive bacteria, propionibacterium acnes and propionibacte ...	2014	24475943
infective endocarditis caused by propionibacterium granulosum.		2015	26665321
[propionibacterium granulosum bare-metal stent infection after drug-eluting balloon].	bare-metal stents are used to treat arterial stenotic lesions. morbidity and mortality are less important compared with other techniques. drug-eluting balloons are often used to treat stent stenosis. we reported the case of a bare-metal stent infection after drug-eluting balloon and a review on the subject.	2015	26055520
aerobic and anaerobic bacteriology of hidradenitis suppurativa: a study of 22 cases.	hidradenitis suppurativa (hs) is a chronic inflammatory skin disease of unclear etiology. the role of bacteria in the pathogenesis of disease remains controversial.	2015	27170935
the wound healing and antibacterial activity of five ethnomedical calophyllum inophyllum oils: an alternative therapeutic strategy to treat infected wounds.	calophyllum inophyllum l. (calophyllaceae) is an evergreen tree ethno-medically used along the seashores and islands of the indian and pacific oceans, especially in polynesia. oil extracted from the seeds is traditionally used topically to treat a wide range of skin injuries from burn, scar and infected wounds to skin diseases such as dermatosis, urticaria and eczema. however, very few scientific studies reported and quantified the therapeutic properties of calophyllum inophyllum oil (cio). in t ...	2015	26406588
antimicrobial activity of pomegranate and green tea extract on propionibacterium acnes, propionibacterium granulosum, staphylococcus aureus and staphylococcus epidermidis.	we used pomegranate extract (pomx), pomegranate juice (pom juice) and green tea extract (gt) to establish in vitro activities against bacteria implicated in the pathogenesis of acne. minimum inhibitory concentrations (mic) of 94 propionibacterium acnes, propionibacterium granulosum, staphylococcus aureus, and staphylococcus epidermidis strains were determined by clinical and laboratory standards institute-approved agar dilution technique. total phenolics content of the phytochemicals was determi ...	2015	26091382
real-time quantitative reverse transcription-polymerase chain reaction to detect propionibacterial ribosomal rna in the lymph nodes of chinese patients with sarcoidosis.	the aim of this study was to investigate the diagnostic value of using the copy number of propionibacterial rrna as a biomarker for sarcoidosis. ribosomal rna of propionibacterium acnes and p. granulosum was measured by real-time quantitative reverse transcription-polymerase chain reaction (rt-pcr) using formalin-fixed and paraffin-embedded tissue of lymph node biopsy from 65 chinese patients with sarcoidosis, 45 with tuberculosis and 50 controls with other diseases (23 with non-specific lymphad ...	2015	25959360
evaluation of anti-acne properties of phloretin in vitro and in vivo.	this study aimed to investigate the anti-acne properties of phloretin in vitro and in vivo.	2016	26212527
antimicrobial activities of ozenoxacin against isolates of propionibacteria and staphylococci from japanese patients with acne vulgaris.	ozenoxacin, a novel non-fluorinated topical quinolone, was assessed for in vitro antimicrobial activity against clinical isolates of propionibacteria and staphylococci according to the broth microdilution method recommended by the clinical and laboratory standards institute. the isolates used in this study were collected from japanese patients with acne vulgaris during a period from 2012 to 2013. the mic90s of ozenoxacin against propionibacterium acnes (n=266), propionibacterium granulosum (n=10 ...	2016	27305898