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lysis of brucellae by the combined action of glycine and a lysozyme-like agent from rabbit monocytes.ralston, doris j. (university of california, berkeley), b. s. baer, and s. s. elberg. lysis of brucellae by the combined action of glycine and a lysozyme-like agent from rabbit monocytes. j. bacteriol. 82:342-353. 1961.-an acid-extractable lytic material was obtained from rabbit monocytes. it acts on a substrate in the walls of brucellae and has properties similar to egg-white lysozyme. brucella melitensis strain rev is is completely resistant to this agent and also to crystalline lysozyme, but ...196113739276
metabolic characterization of the genus brucella. i. statistical evaluation of the oxidative rates by which type i of each species can be identified.meyer, margaret e. (university of california, davis), and h. s. cameron. metabolic characterization of the genus brucella. i. statistical evaluation of the oxidative rates by which type i of each species can be identified. j. bacteriol. 82:387-395. 1961.-the oxidative uptake rates on 11 amino acid and seven carbohydrate substrates were determined for 75 strains of brucellae that had been identified by the conventional determinative methods as brucella melitensis type i, brucella abortus type i, ...196113770011
metabolic characterization of the genus brucella. iii. oxidative metabolism of strains that show anomalous characteristics by conventional determinative methods.meyer, margaret e. (university of california, davis). metabolic characterization of the genus brucella. iii. oxidative metabolism of strains that show anomalous characteristics by conventional determinative methods. j. bacteriol. 82:401-410. 1961.-the oxidative metabolic patterns were determined on 83 strains of brucellae that had been described as "atypical" because they differed in one or more characteristics or because they had been isolated from an abnormal host (other than the natural reser ...196113770014
metabolic characterization of the genus brucella iv. 3: correlation of oxidative metabolic patterns and susceptibility to brucella bacteriophage, type abortus, strain.meyer, margaret e. (university of california, davis). metabolic characterization of the genus brucella. iv. correlation of oxidative metabolic patterns and susceptibility to brucella bacteriophage, type abortus, strain 3. j. bacteriol. 82:950-953. 1961.-a total of 212 strains of brucellae that had been identified as brucella melitensis, b. abortus, b. suis, or b. neotomae by their oxidative metabolism were tested for their susceptibility to brucella bacteriophage, type abortus, strain 3. it was ...196116561925
metabolic and bacteriophage identification of brucella strains described as brucella melitensis from cattle. 196214473151
[isolation of brucella melitensis from the fleas xenopsylla conformis gathered from the burrows of wild rodents]. 196214482981
[natural innate immunity for brucella melitensis. i. relation with properdin, complement, bactericidal properties of serum and the formation of specific antibodies]. 196214076958
autoradiographic studies on intracellular growth of brucella melitensis and thymineless e. coli. 196213862521
immunization against brucella infection. 8. the response of cynomolgus philippinensis, guinea-pigs and pregnant goats to injection by the rev i strain of brucella melitensis.experiments have been carried out on monkeys, goats and guinea-pigs to define as closely as possible the degree of attenuation of the rev i strain of b. melitensis. earlier studies had conclusively demonstrated the effectiveness of the strain as an immunizing agent of the three animal species and had suggested that the degree of attenuation was such as to warrant limited study in humans. results of such a limited study suggested more intensive measurement of the virulence of the strain in other ...196213889789
an outbreak of brucellosis in bhiwani. the danger of infection with brucella melitensis. 196213933665
immunization against brucella infection: ix. the response of the guinea pig to the immunizing strain (rev. 1) of brucella melitensis. 196219971011
natural infection of sheep by brucella melitensis in argentina. 196313940568
[natural infection of sheep by brucella melitensis in the argentine republic]. 196313940569
antigenicity of some brucella melitensis cell fractions.glenchur, harry (minneapolis veterans administration hospital, and university of minnesota school of medicine, minneapolis), ulysses s. seal, horace h. zinneman, and wendell h. hall. antigenicity of some brucella melitensis cell fractions. j. bacteriol. 85:363-368. 1963.-the components of a brucella melitensis strain were obtained by differential centrifugation and diethylaminoethyl-cellulose ion-exchange chromatography. rabbit antisera to these brucella fractions were tested for agglutinins, pr ...196313948439
[colimycin-resistant forms of brucella melitensis]. 196313995440
[on the biological characteristics of nonagglutinable cultures of brucella melitensis]. 196314070194
comparison of living vaccines in producing immunity against natural brucella melitensis infection in sheep and goats in iran. 196414105237
[the sensitivity of brucella melitensis and brucella suis to the tb brucellophage]. 196414131339
response of normal and immune histiocytes of various animal species to infection by brucella melitensis. 196414166593
[brucella melitensis and brucella phages]. 196414176846
motility-promoting effect of the brucella abortus and brucella melitensis endotoxin on the smooth uterine muscle. 196414190080
ampicillin in treatment of salmonella typhi carriers and brucella melitensis septicaemia. 196414193974
immunization against brucella infection. 10. the relative immunogenicity of brucella abortus strain 19-ba and brucella melitensis strain rev i in cynomolgus philippinensis.continuing previous studies, the authors investigated the immunogenicity of low doses of brucella melitensis strain rev i in cynomolgus monkeys challenged by the respiratory route and compared the efficacy of rev i vaccine with that of vaccine from br. abortus strain 19-ba.challenge with the virulent br. melitensis strain 6015 indicated that 19-ba vaccine was considerably more effective when administered intracutaneously than subcutaneously, whereas with rev i vaccine the difference was slight, ...196414196815
immunogenicity of a gamma-irradiated brucella melitensis vaccine in mice. 196414234061
the role of the goat in human brucellosis in india with particular reference to infection with brucella melitensis. 196414253378
comparative distribution of brucella abortus, brucella melitensis, and brucella ovis in experimentally infected pregnant sheep. 196414266901
human infection with the british strain of brucella melitensis (brucella abortus type 5). 196514267948
[chemical composition of brucella walls. glycosaminopeptide from brucella abortus and brucella melitensis]. 196514290928
[attempt at vaccination of guinea pigs against brucella melitensis by means of a killed vaccine]. 196514336050
the presence of brucella melitensis infection in sheep in the transvaal. 19655895645
[cellular resistance to bacterial infection. iv. active immunization and resistance of the macrophages of ncs mice to the intracellular multiplication of listeria monocytogenes, corynebacterium kutscheri and brucella melitensis]. 19665903387
subacute endocarditis due to brucella melitensis. a case report. 19665968929
[immunization against brucella melitensis with a liver strain of attenuated virulence. i. isolation and characterization of the strain cultured in ox bile tryptose-agar]. 19665992755
[the activity of energy exchange enzyme systems in brucella melitensis of various degrees of virulence]. 19666004909
duration of the immunity produced in goats by the rev. 1 brucella melitensis vaccine. 19666007463
the degree of protection given by living vaccines against experimental infection with brucella melitensis in goats.it has been shown by a number of workers that brucella melitensis rev. 1 vaccine confers good protection against infection with br. melitensis in sheep and goats. although br. abortus strain 19 vaccine is widely used in some countries to protect sheep, it has not been evaluated for caprine brucellosis. the purpose of the experiment reported in this paper was to determine and compare the degree of protection given by living vaccines prepared from rev. 1 and strain 19 and by a non-agglutinogenic s ...19665295563
immunization against brucella infections. effects of graded doses of viable attenuated brucella melitensis in humans. 19665329427
[the incidence of brucella melitensis in animals in syria]. 19674969887
[anatomoclinical findings in 3 cases of endocarditis due to brucella melitensis]. 19675606377
effect of living rev. 1 vaccine in producing long-term immunity against brucella melitensis infection in sheep in iran. 19675625649
experimental brucella melitensis infection in local goats-opsonoc- ytophagic test on blood. 19675626592
rev. 1 brucella melitensis vaccine. the stability of the degree of attenuation. 19675634114
rev. 1 brucella melitensis vaccine. serological reactions in maltese goats. 19675634117
ampicillin "penbritin" in the treatment of acute brucella melitensis septicaemia and salmonella typhi urinary carriers. 19676022422
antigenic relationship of brucella ovis and brucella melitensis.immune sera were prepared in rabbits by the injection of living and acetone-killed cells of brucella ovis and smooth and rough b. melitensis. the use of whole-cell antigens in agglutination and agglutinin-absorption tests revealed little relationship between b. ovis and smooth b. melitensis, although there was extensive cross-agglutination between b. ovis and rough b. melitensis. the use of water-soluble antigens prepared from ultrasonically treated cells of the three strains revealed extensive ...19676032505
[immunological properties of a phenol-insoluble extract from brucella melitensis (p.i. fraction)]. 19676048204
response of the vaccine strain of brucella melitensis rev i to erythritol. 19676066058
[immunological analysis of ribosomal proteins in escherichia coli, bacillus subtilis and brucella melitensis]. 19684989000
further studies on the duration of the immunity produced in goats by the rev. 1 brucella melitensis vaccine. 19685648807
immunological behaviour of a crude brucella melitensis lysate. 19685680413
the use of three vaccines against brucella melitensis in sheep. 19685691352
a case of brucellosis due to consumption of improperly pasteurised milk. the danger of infection with brucella melitensis. 19685694652
serum-mediated immune cellular responses to brucella melitensis rev i. 3. infection of macrophages fixed-to-glass. 19685706990
[agglutinins and infection in mice due to brucella melitensis]. 19685714010
[immunization of goats against brucellosis with a live attenuated strain of brucella melitensis 899b]. 19685735891
serum-mediated immune cellular responses to brucella melitensis. i. role of a macrophage-stimulating factor in promoting ingestion of brucella by streptomycin-protected cells.injection of rabbits with living brucella melitensis rev i induced the appearance of a macrophage-stimulating-factor (msf) in the sera of these animals. msf was involved in ingestion of bacilli, hastening the formation of protected loci as measured by the addition of lethal amounts of dihydrostreptomycin. when sufficient time had been allowed for effective ingestion, streptomycin had little effect. this in turn allowed for multiplication of bacilli intracellularly in the presence of 5 to 250 mug ...19684174059
surface antigens of smooth brucellae.surface antigens of smooth brucellae were extracted by ether-water, phenol-water, trichloroacetic acid, and saline and examined by immunoelectrophoresis and gel diffusion with antisera from infected and immunized rabbits. ether-water extracts of brucella melitensis contained a lipopolysaccharide protein component, which was specific for the surface of smooth brucellae and was correlated with the m agglutinogen of wilson and miles, a polysaccharide protein component devoid of lipid which was not ...19684176644
outbreak of brucella melitensis type 2 infection in london.an outbreak of seven cases of brucella melitensis infection in london was traced to italian pecorino cheese (cheese made from unpasteurized sheep's milk) which had been obtained from village markets in central italy, brought back to england, and distributed to the affected persons.it is emphasized that pecorino cheese made from unpasteurized milk should not be eaten unless it is known to have been stored for at least 90 days, the period during which these cheeses have been shown to become free f ...19695766127
serum-mediated immune cellular responses to brucella melitensis rev 1. ii. restriction of brucella by immune sera and macrophages. 19695768949
serum-mediated immune cellular responses to brucella melitensis. iv. infection of macrophages under anaerobic conditions.immune mechanisms active against brucella were studied under conditions of oxygen deficiency. b. melitensis grew in rabbit serum-tyrode medium flooded with n(2) and co(2) gas mixtures. immune sera from rabbits injected with b. melitensis strain rev i possessed growth-inhibitory activity that operated in anaerobic environments against rev i and virulent strain 6015. when mixed with macrophages, immune sera mediated even greater inhibition of bacterial growth and slowed the spread of infection thr ...19695773005
[inborn natural immunity to brucella melitensis. ii. genetic factors of hereditary immunity to brucella melitensis in goats]. 19695802750
[comparison of the chemical composition a lipopolysaccharide fraction and of a polysaccharide fraction isolated from brucella melitensis]. 19695804497
vaccination of guinea-pigs with rev. i brucella melitensis vaccine. the response to very large and very small doses. 19695809565
a trial in guinea-pigs of four methods of vaccination against brucella melitensis infection. 19695809566
reticuloendothelial function in the isolated perfused liver. 3. phagocytosis of salmonella typhosa and brucella melitensis and the blockade of the reticuloendothelial system. 19695810630
relative value of the agglutination test complement fixation test and coombs (antigbulin) test in the detection of brucella melitensis infection in sheep. 19695813554
on the fatty acids of brucella abortus and brucella melitensis. 19694978225
immunization against brucella infections: serological and immunological studies on a soluble antigen from brucella melitensis. 19694980600
antigenic relationship of brucella ovis to brucella abortus and brucella melitensis using the complement fixation test. 19695005098
brucella melitensis rev i vaccine. experiments on the duration of immunity. first pregnancy challenge. 19695388661
the preservation of brucella melitensis rev. i vaccine. 19705498558
brucella melitensis infection in female kids born into a heavily infected environment. 19705503825
vaccination of goats with reduced doses of rev. i brucella melitensis vaccine. 19705503923
[a case of brucellosis (brucella melitensis) in a child from the region of podor (senegal)]. 19705508474
effect of erythritol on different strains of brucella melitensis. 19705522254
[anti-brucellosis human vaccination with an antigenic fraction of brucella melitensis]. 19704913684
an epizootic of brucella melitensis infection in texas. 19704922193
immunization against brucella infections: immune response of mice, guinea pigs, and cynomolgus philipinensis to live and killed brucella melitensis strain rev. i administered by various methods. 19704992339
[on the lipopolysaccharide fractions extracted with phenol from brucella melitensis]. 19704997618
brucella melitensis strain rev i as a vaccine for cattle. 19715005602
comparison of various serological tests on the milk of sheep in relation to the isolation of brucella melitensis. 19715102236
serum-mediated immune cellular responses to brucella melitensis. 7. the separation and assay of serum globulins responsible for macrophage stimulation and brucella inhibition. 19715115180
a comparison of the tube agglutination and card tests for the diagnosis of brucella melitensis infection in humans. 19715137626
[live anti-brucella melitensis strain 899b vaccine for the immunization of goats]. 19715288199
use of 51cr in studies on cellular immunity to mycobacterium tuberculosis, brucella melitensis and poliovirus, type i. 19715543710
[study of a stable strain of brucella melitensis spheroplasts (l forms)]. 19715552324
brucella melitensis in impala (aepyceros melampus). 19715575513
serum-mediated immune cellular responses to brucella melitensis. vi. the sequence of cellular and serologic changes after immunization of the rabbit with the rev i vaccine strain. 19714106742
[comparison of immunological properties of 2 lipopolysaccharide fractions and of 1 polysaccharide fraction isolated from brucella melitensis]. 19714111139
[comparative chemical studies on the polysaccharide component of the somatic antigens of brucella abortus s19 and brucella melitensis 16m]. 19714400726
sensitization and recall of anti-brucella immunity in guinea pig macrophages by attenuated and virulent brucella.peritoneal macrophages from guinea pigs vaccinated with strain rev i of brucella melitensis were only moderately activated thereby to limit, in an in vitro system, the intracellular growth of rev i bacilli. nevertheless, the appropriate memory cells had been primed, as demonstrated by the observation that reinfection of animals with virulent b. melitensis followed by intraperitoneal inoculation of mineral oil called forth macrophages in immunized guinea pigs which inhibited strongly the intracel ...197116557954
medium-dependent activity of immune serum on brucella-infected macrophages.medium constituents affect the inhibitory action of anti-brucella melitensis serum during in vitro infection of oil-induced peritoneal macrophages of the guinea pig with b. melitensis.197116557979
[on the bactericidal power of samples of human blood against strains of brucella melitensis and brucella abortus]. 19724205694
infection at the subcellular level. i. localization of intravenously injected brucellae in the vacuolar apparatus of cells of guinea pig liver.the distribution of brucella melitensis in various tissues and in subcellular fractions obtained from liver was investigated to evaluate the initial phases of brucellosis in the guinea pig. fifty minutes after intravenous infection, brucellae were found principally in the blood and liver, with a substantial number recovered from spleen. fractionation of liver established that most bacteria were found in the mitochondrial plus lysosomal (m + l) fraction; a significant number, however, sedimented ...19724344302
brucella melitensis rev. 1 and brucella abortus 45-20 vaccines in goats: immunity. 19724626469
stimulation of antibacterial vaccination in mice by polyadenylic acid: polyuridylic acid complex.the effect of polyadenylic acid:polyuridylic acid complex (poly a:u) on immunization was investigated in mice vaccinated by killed brucella melitensis cells suspended in incomplete adjuvant or in saline. addition of 300 mug of poly a:u to vaccines rendered 3 x 10(8)b. melitensis cells in saline as immunogenic as 3 x 10(11) cells in oil adjuvant against a severe b. abortus challenge. in the mouse and brucella system, poly a:u exerts an adjuvant effect on immunity but does not stimulate production ...19724637296
drug sensitivity of brucella melitensis. 19724651251
[characterization of the interferon induced in mice following infection with "brucella melitensis"]. 19734723417
surface morphology of peritoneal macrophages during the attachment of brucella melitensis.when macrophages from immunized rabbits are in the act of phagocytosis of the homologous organism, the macrophages are seen by scanning electron microscopy to possess undulating membranes and microvilli at various stages of formation and spatial relationships to the organisms.19734742976
infection at the subcellular level. ii. distribution and fate of intravenously injected brucellae within phagocytic cells of guinea pigs.cells of brucella melitensis strain 16 m were labeled with (32)p. when injected into normal guinea pigs, labeled, viable bacteria were taken up and inactivated in liver and spleen during the 60 min after infection. both uptake and inactivation increased if brucellae were coated with antibrucella antibody. neither viability nor radioactivity were lost when labeled brucellae were incubated for 60 min in vitro with normal guinea pig blood, liver homogenates, or in defined medium. incubation for 12 ...19734748943
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