Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [the in vitro sensitivity of 24 strains of pseudomonas pseudomallei to antibiotics (author's transl)]. | 1976 | 1021818 | |
| use of stable, sensitized cells in an indirect microhemagglutination test for melioidosis. | two evaluations were carried out in this study. the first was a comparison of the standard tube test with the automated microtitration test for the detection of antibodies to pseudomonas pseudomallei by the indirect hemagglutination method. data from this comparison indicated that the tests were equivalent. the second evaluation consisted of reproducibility studies on two lots of pyruvic aldehyde-stabilized sensitized erythrocytes in comparison with freshly prepared sensitized erythrocytes in th ... | 1977 | 557498 |
| the isolation of pseudomonas pseudomallei from soil in north queensland. | 1977 | 588173 | |
| wound infection by an indigenous pseudomonas pseudomallei-like organism isolated from the soil: case report and epidemiologic study. | a 27-year-old farmer in the oklahoma panhandle was pinned under his overturned tractor for 2 hr and received superficial and deep lacerations. he contracted an infection of a pelvic wound with an organism that had cultural and biochemical characteristics identical to those of pseudomonas pseudomallei. identical organisms were recovered from soil taken from the site of the accident. the organism isolated from the wound proved to be less virulent in guinea pigs than usual laboratory strains of p. ... | 1977 | 833442 |
| [phagocytability of pseudomonas pseudomallei]. | experiments were conducted on the cell culture of macrophages of animals significantly differing by the extent of resistance to melioidosis; the presence of correlation between the extent of the animal natural immunity and the intensity of dying of the microbes in the test system was demonstrated. the causative agent of melioidosis proved to be more resistant to phagocytosis with guinea pig macrophages than e. coli. ps. aeruginosa and a. mallei. it was impossible to establish any relationship be ... | 1978 | 665019 |
| melioidosis in a sulphur-crested cockatoo (cacatua galerita). | a case of melioidosis in a sulphur-crested cockatoo (cacatua galerita) kept as a pet in townsville is described. this case was characterised by liver necrosis with both a heterophil and mononuclear cell inflammatory response associated with giant cells. pseudomonas pseudomallei was isolated by blood plate culture and guinea pig inoculation. this is the first case of melioidosis reported in a native bird in australia. | 1978 | 687299 |
| melioidosis presenting as prostatitis--a case report from sabah. | previous reports of melioidosis in sabah are reviewed and a detailed account of a case, presenting as prostatitis, in a 40-year-old british male is given. the history suggested that the organism, pseudomonas pseudomallei, was transmitted by a fly which entered the eye. diagnosis was delayed and treatment presented some difficulty, the organism being relatively insensitive to amplicillin and gentamicin. co-trimoxazole was the most effective, followed by minocycline. cure was eventually achieved a ... | 1978 | 725999 |
| identification of pseudomonas pseudomallei in the clinical laboratory. | ninety-one strains of pseudomonas pseudomallei were tested in the api 20e system and in equivalent conventional tests. except for utilisation of citrate there was good correlation between api and conventional tests. seven-digit profiles were constructed from each strain after 48 hours' incubation, and numerical codes 2 006 727, 2 206 706, 2 206 707, and 2 206 727 accounted for 77% of strains tested. api 20 e, in combination with tests for heat stability of alkaline phosphatase, resistance to col ... | 1979 | 381328 |
| [effect of d,l-ureidosuccinic dihydrazide on the biological properties of pseudomonas pseudomallei and salmonella typhimurium]. | 1979 | 398137 | |
| an improved screening technique for isolation of pseudomonas pseudomallei from clinical specimens. | a selective medium consisting of trypticase soy agar with 4% glycerol, 5 mg/l crystal violet, 50 mg/l neutral red and 4 mg/l of gentamicin was devised for isolation of pseudomonas pseudomallei from clinical specimens. absorption of neutral red was found to be suitable for differentiating this organism from other bacteria, while gentamicin was effective in selecting ps. pseudomallei from organisms commonly found in clinical material. the medium was more suitable for screening clinical specimens t ... | 1979 | 460953 |
| isolation of pseudomonas pseudomallei from clay layers at defined depths. | twelve strains of pseudomonas pseudomallei were isolated from the soil and water of a sheep paddock over a two-year period. the organism was recovered from the clay layer of the soil profile as well as from water that seeps into this layer during the "wet" season. five isolates were obtained before the commencement of the "wet" season; environmental factors appear to play an important role in the survival of ps. pseudomallei during the "dry" season. lower isolation rates were recorded than those ... | 1979 | 507042 |
| nosocomial infection due to pseudomonas pseudomallei: two cases and an epidemiologic study. | pseudomonas pseudomallei was recovered from urine specimens of two patients who acquired the organism after they were admitted to a hospital in a region in which it is endemic. both patients were diabetic and both had urethral catheters passed while they were hospitalized. samples of soil taken from the hospital grounds yielded an isolate of p. pseudomallei that was identical biochemically and by antibiogram to the two isolates recovered from the urine specimens of the two patients. the two pati ... | 1979 | 542764 |
| acute septicemic melioidosis occurring in a child with acute lymphoblastic leukemia. | a 13-year old boy with acute lymphoblastic leukemia on chemotherapy developed neutropenia and acute cellulitis progressing to fulminating septicemia due to pseudomonas pseudomallei. septicemic melioidosis should be considered in the differential diagnosis of a febrile illness in children who are susceptible to infections. | 1980 | 6931670 |
| influence of d,l-ureidosuccinic acid dihydrazide on some biological properties of pseudomonas pseudomallei and of salmonella typhimurium. | the changes induced in strains of pseudomonas pseudomallei and salmonella typhimurium under the action of d.l-ureidosuccinic acid dihydrazide were characterized. a decrease of the speed of multiplication in vitro and of the oxygen consumption was established. the virulence of the strains was reduced and their susceptibility to phagocytosis in vitro was increased. | 1980 | 7001807 |
| primary gram negative pneumonia in adults in papua new guinea. | a retrospective review of gram-negative bacteraemia in papua new guinean adults revealed four cases of primary gram negative pneumonia over a two-year period. patients with primary gram negative pneumonia constituted less than 1% of all pneumonias admitted to the medical ward. pseudomonas pseudomallei, haemophilus influenzae and klebsiella pneumoniae were the aetiologic agents. three of four patients died following a fulminant course. it is concluded that primary gram-negative pneumonia in papua ... | 1980 | 7008428 |
| cross-reaction to legionella pneumophila antigen in sera with elevated titers to pseudomonas pseudomallei. | a significantly greater incidence (p less than 0.005) of legionella pneumophila microagglutination titers greater than or equal to 32 was found in sera with elevated titers to pseudomonas pseudomallei as compared with sera with negative titers for p. pseudomallei antibodies. the greater incidence of l. pneumophila titers in these sera suggests that l. pneumophila and p. pseudomallei share an antigen. the incidence of l. pneumophila microagglutination titers of greater than or equal to 32 in sera ... | 1980 | 7354127 |
| meliodosis. | during the five-month wet season of 1977-1978 in northern queensland, six patients with bacteriologically proven melioidosis were successfully treated at the townsville general hospital, the clinical course and management of each case and laboratory findings are described. factors which predisposed them to infection with pseudomonas pseudomallei were diabetes mellitus, cancer, alcoholism, malnutrition, trauma, and pregnancy. successful treatment of melioidosis relied on prompt laboratory diagnos ... | 1980 | 7393058 |
| pseudomonas pseudomallei in an anopthalmic orbit. | a 21-year old man sustained multiple facial fractures and skin lacerations during an automobile accident, with resultant necrosis of the left upper eyelid and exposure of the cornea. bacterial and secondary fungal corneal ulceration and perforation occurred, leading to enucleation. cultures from the noninfected anophthalmic orbit approximately eight weeks after enucleation yielded pseudomonas pseudomallei. this is the second isolate of this domallei. this is the second isolate of this organism i ... | 1980 | 7396773 |
| [postinfection immunity in melioidosis]. | experiments on the reinfection of laboratory animals with melioidosis revealed that guinea-pigs and white mice developed pronounced resistance to the disease, accompanied by the objective [corrected] signs of immunologic transformation (allergization, the presence of specific humoral antibodies, and increase in the phagocytic activity of the cells of the macrophage system). in golden hamsters, highly sensitive to infection with pseudomonas pseudomallei culture, the process of the "all or nothing ... | 1980 | 7405455 |
| septic arthritis of the sternomanubrial joint due to pseudomonas pseudomallei. | 1980 | 7417354 | |
| genito-urinary infections with pseudomonas pseudomallei in australian aboriginals. | 1980 | 7434413 | |
| melioidosis in a galah (cacatua roseicapilla). | a second case of a natural infection of melioidosis in a native bird is described. pseudomonas pseudomallei was isolated in pure culture from the liver, spleen and intestinal contents of a galah (cacatua roseicapilla). the case was characterised by focal granuloma formation, often associated with necrosis, in the brain, lungs, liver, spleen and kidneys. | 1980 | 7436921 |
| glucan-induced enhancement of host resistance to selected infectious diseases. | we conducted studies with mice, rats, and monkeys which demonstrated the ability of glucan to induce either nonspecific or specific enhancement of host resistance to infectious diseases. intravenous pretreatment of mice with glucan significantly enhanced the survival of mice challenged with either venezuelan equine encephalomyelitis (vee) virus or rift valley fever virus. pretreatment was beneficial when initiated 3 days before challenge with vee virus and 7 days before challenge with rift valle ... | 1980 | 7439978 |
| melioidosis in the northern territory of australia. | melioidosis is being diagnosed with increasing frequency in the northern part of the northern territory, but the mortality rate remains high in the acute septicaemic form of the disease largely because of associated chronic debilitating illnesses. this paper reviews epidemiological and clinical features of human melioidosis in 37 cases seen between 1960 and 1979. infection with pseudomonas pseudomallei is most often contracted during the wet season by persons who have regular contact with soil o ... | 1981 | 7231282 |
| melioidosis with acute meningoencephalomyelitis in a horse. | a case of acute meningoencephalomyelitis caused by infection with pseudomonas pseudomallei is described. clinically there was inability to stand, opisthotonus, facial paralysis and nystagmus, rapidly progressing to violent struggling. gross examination revealed malacia and haemorrhage in the medulla oblongata and adjacent spinal cord. microscopically there were disseminated focal neutrophilic accumulations in affected areas, perivascular cuffing with mononuclear cells and lymphocytes and marked ... | 1981 | 7236143 |
| [antigenic structure of pseudomonas pseudomallei]. | the antigenic scheme has been proposed on the basis of the immunoelectrophoretic study of aqueous-saline extracts from acetone-dried microbial cells belonging to 29p. pseudomallei strains. the proposed scheme consists of 19 precipitinogens; of these, 13 have been shown to be common to all strains under study, the remaining precipitinogens being variable. all antigens are characterized by their charge and the degree of mobility in the electric field, their molecular weight, thermal resistance and ... | 1981 | 7269904 |
| laboratory-acquired infection with pseudomonas pseudomallei (melioidosis). | 1981 | 7290119 | |
| [ecological aspects of pseudomonas pseudomallei interactions with ixodid ticks]. | 1981 | 7340413 | |
| persistence of pseudomonas pseudomallei in soil. | 1981 | 7342941 | |
| relationship and significance of specific immunoglobulin m antibody response in clinical and subclinical melioidosis. | thirty-six hospitalized patients with circulating antibody to pseudomonas pseudomallei were classified as having either clinical or subclinical melioidosis after full clinical examinations and supplementary radiological and culture investigations. qualitative estimations of immunoglobulin m (igm) antibody response were determined by complement fixation, indirect hemagglutination, and immunofluorescence, and the estimations were correlated with the clinical findings in each patient. an attempt wa ... | 1981 | 7026605 |
| demonstration of human antibodies to pseudomonas pseudomallei by indirect fluorescent antibody staining. | a rapid, reliable immunofluorescent assay for human antibodies to pseudomonas pseudomallei was devised. the method was found to be sensitive and specific by inhibition tests and by tests for cross reactivity with antisera and cells of closely related pseudomonads other than pseudomonas mallei. preliminary studies suggest that the technique may be useful as a screening test for the detection of melioidosis and that demonstration of specific igm by immunofluorescence may be of value in differentia ... | 1981 | 7029435 |
| fatal bronchopneumonia in a young orang utan caused by pseudomonas pseudomallei. | 1982 | 7080412 | |
| microbiological and immunological studies in a case of human melioidosis diagnosed in denmark. | the first case of melioidosis reported in denmark was in a 64-year-old man 2 weeks after his return from a 3-week visit to kenya. the clinical course was characterized by septicaemia and pseudomonas pseudomallei was isolated from repeated blood cultures, urine and sputum. transient impairment of cellular immunity was observed. during the convalescence a cell-mediated immune response against the pathogen was detected by the lymphocyte blast transformation test. two precipitins against p. pseudoma ... | 1982 | 7163779 |
| [studies of r and s forms of pseudomonas pseudomallei. ii. in vitro susceptibility to phagocytosis by human, guinea pig and chicken peripheral blood leukocytes]. | 1982 | 7171037 | |
| [studies of r and s forms of pseudomonas pseudomallei. sensitivity to bactericidal effect of normal human, guinea pig and chicken sera]. | 1982 | 7171038 | |
| pathological changes in goats experimentally inoculated with pseudomonas pseudomallei. | sixteen goats were inoculated subcutaneously or intraperitoneally with cultured pseudomonas pseudomallei isolated from a goat. they showed either acute or chronic phase of disease. when inoculated intraperitoneally, animals suffered from a septicemic illness of short duration accompanied with micro-abscesses scattered widely throughout the body. in animals subcutaneously inoculated no clinical signs were exhibited, but the disease was of rather long duration, and lesions were large and localized ... | 1982 | 7186613 |
| [biological effect of d,l-ureidosuccinic acid dihydrazide on pseudomonas pseudomallei and salmonella typhimurium]. | 1982 | 6293275 | |
| biological effect of d,l-ureidosuccinic acid dihydrazide on pseudomonas pseudomallei and salmonella typhimurium. | 1982 | 6293407 | |
| [studies of r and s forms of pseudomonas pseudomallei. i. morphology of colonies and virulence for albino mice and guinea pigs]. | 1982 | 6763458 | |
| melioidosis: recrudescence with a strain resistant to multiple antimicrobials. | we describe a recent case of melioidosis presenting classically in a young vietnam veteran. the case demonstrates extensive antibiotic resistance in this isolate and failure of ceftriaxone, despite its in vitro efficacy. other multiple antimicrobial regimens also failed. melioidosis remains a concern in patients who have previously lived in endemic areas. a high level of diagnostic suspicion is required, especially in patients with a febrile illness or tuberculosis-like presentations. early dete ... | 1983 | 6870060 |
| epididymo-orchitis due to pseudomonas pseudomallei. | we report the first case of epididymo-orchitis caused by pseudomonas pseudomallei. the diagnosis was made by isolation of the organism from testicle pus and urine. treatment was successful with chloramphenicol and co-trimoxazole. | 1983 | 6887385 |
| successful treatment of melioidosis caused by a multiresistant strain in an immunocompromised host with third generation cephalosporins. | a 32-yr-old woman with active systemic lupus erythematosus receiving prednisone and azathioprine developed lung abscesses of the right lower lobe caused by pseudomonas pseudomallei, which was resistant concomitantly to chloramphenicol, co-trimoxazole, and tetracycline, but highly sensitive to a new cephalosporin, ceftazidime. melioidosis was treated successfully with lobectomy and parenteral ceftazidime, which was given for 2 months without major side effects. ceftazidime, being bactericidal, ma ... | 1983 | 6342484 |
| [drug sensitivity of pseudomonas pseudomallei]. | 1983 | 6351503 | |
| evaluation of the api 20e and microbact 24e systems for the identification of pseudomonas pseudomallei. | one-hundred isolates of pseudomonas pseudomallei were used to evaluate the api 20e and microbact 24e rapid identification systems. the api 20e system identified 50% of the isolates using the revised 1979 manual only, and 63% when referral was made to the computer centre. a higher identification rate (69 and 87%, respectively) was achieved with a longer incubation period of 96 h. the microbact 24e system identified 84% of the isolates as p. pseudomallei using the revised 1983 manual, and 100% whe ... | 1983 | 6362175 |
| biological effect of l-asparagine acid hydrazide on pseudomonas pseudomallei and salmonella typhimurium. | 1983 | 6370195 | |
| [diagnosis of the whitmore bacillus in the laboratory]. | after realization of a new synthetic medium for whitmore bacillus enrichment and isolation, the authors describe a new specific and immunologic process for pseudomonas pseudomallei isolation from very polluted samples. | 1983 | 6370480 |
| [identification of pseudomonas pseudomallei]. | 1983 | 6194365 | |
| [the nature of changes in the antigenic spectrum of the causative agent of melioidosis during animal passage]. | the comparative analysis of the antigenic spectra of pseudomonas pseudomallei museum and subcultured strains, carried out by the method of immunoelectrophoresis, has revealed that, along with an essential increase in the virulence of p. pseudomallei for white mice and changes in the morphology of colonies, a decrease in the amount of detected precipitinogens occurs in the process of subculturing. the immunoelectrophoregrams of the subcultured variants show the absence of antigens 5, 6 and the si ... | 1983 | 6415970 |
| [a study of the possibility of conjugated transmission of the rp4 plasmid from pseudomonas aeruginosa by strains of pseudomonas mallei and pseudomonas pseudomallei]. | 1983 | 6443857 | |
| [use of transformation for the chromosome mapping of pseudomonas pseudomallei]. | the mapping of the chromosome sections in p. pseudomallei, responsible for the synthesis of histidine, has been carried out with the use of two- and three-factor crossing. two new groups of marker linkage have been found: his 522 with ilv 658 and his 37 with asp 37 glu 37. the linkage of some of the existing histidine mutations with locus his 37 has been revealed and the relative position of the markers in this linkage group has been shown. | 1983 | 6573084 |
| [r- and s-forms of pseudomonas pseudomallei. vi. ultrastructural characteristics]. | 1983 | 6650229 | |
| granulomatous orchitis and periorchitis caused by pseudomonas pseudomallei in a goat. | 1984 | 6710827 | |
| melioidosis in far north queensland. a clinical and epidemiological review of twenty cases. | during the last 4 years, 20 cases of clinical melioidosis were diagnosed in the geographical area between tully and thursday island. sixteen were diagnosed by culture of pseudomonas pseudomallei, and four by positive serology with appropriate clinical features. most cases occurred during or after a heavy wet season. all patients were adult, and males predominated. farmers and stockmen represented predisposed populations due to their prolonged soil contact. ten patients were white australians, si ... | 1984 | 6731679 |
| the prevalence of human melioidosis in northern queensland. | sera from 9,047 individuals from northern queensland were examined for the presence of hemagglutinating antibodies to pseudomonas pseudomallei, the causative agent of melioidosis, and 512 (5.7%) were found to have titers of 1:40 or greater. the distribution of positive reactors in various groups was uneven, and significantly higher prevalences of positive antibody titers were found in the sera from aborigines (7.9-10.6%), torres strait islanders (7.8%), vietnamese refugees (29%) and from persons ... | 1984 | 6731680 |
| first report of septicaemic melioidosis in hong kong. | septicaemia due to pseudomonas pseudomallei was found in five patients; it complicated pneumonia in three. four patients were old and had diabetes mellitus; the fifth patient, though young, was immunocompromised by steroid therapy. the clinical features were indistinguishable from those of other gram-negative septicaemia. four of the patients died. this was the first report of septicaemic melioidosis in hong kong where the disease might be endemic. soil sampling and serological survey gave furth ... | 1984 | 6485053 |
| in vitro activity of various cephalosporins against pseudomonas pseudomallei. | 1984 | 6491381 | |
| pleuropulmonary melioidosis in a cambodian refugee. | a 47-year-old cambodian refugee presented with an acute respiratory illness that featured consolidation of the lower lobe of the left lung and progressive involvement of the adjacent pleura caused by pseudomonas pseudomallei. initial difficulty in identifying the organism resulted in an inadequate duration of therapy. chronic pleural disease followed, and the organism became resistant to many antibiotics during therapy. a diagnosis of pleuropulmonary melioidosis should be entertained and the mic ... | 1984 | 6498689 |
| melioidosis and bilateral third-nerve palsies. | central nervous system involvement in melioidosis is unusual. we describe a 34-year-old man who developed a pseudomonas pseudomallei meningitis, manifested as bilateral third-nerve palsies, 13 years after having been in southeast asia. diagnosis was established by a fourfold rise in the serum antibody titer for the bacterium. recovery occurred after treatment with rifampin, isoniazid hydrochloride, ethambutol, and trimethoprim-sulfamethoxazole. since a long latent period from exposure to overt i ... | 1984 | 6537830 |
| [nature of pseudomonas pseudomallei antigens common to some species of microorganisms]. | an antigen, common for the infective agents of glanders , tularemia, plague, pseudotuberculosis, cholera and brucellosis, has been obtained from the aqueous saline extract of p. pseudomallei by means of affinity chromatography on antibody sorbent. the isolated antigen has proved to be of a protein-polysaccharide-lipid nature, to have insignificant cathode mobility and to constitute a component of o-antigen. it has also been found to be antigenically related to the tissues of melioidosis-sensitiv ... | 1984 | 6203267 |
| [relative biological effect of l-aspartic acid hydrazide on pseudomonas pseudomallei and salmonella typhimurium]. | 1984 | 6377831 | |
| [spontaneous genetic transformation in pseudomonas pseudomallei]. | spontaneous genetic transformation has been registered in pseudomonas pseudomallei cells. transforming frequencies registered reach 10(-4)-10(-5). spontaneous transformation has been simulated for pseudomonas pseudomallei in soil. intrageneric spontaneous transformation has been demonstrated to occur between pseudomonas pseudomallei and pseudomonas mallei. | 1985 | 3842757 |
| pseudomonas pseudomallei in southern thailand. | the distribution of pseudomonas pseudomallei was studied in soil and water from various sources of songkla province, southern thailand. p. pseudomallei was isolated from the surface soil of rubber plantations (60.9%) and from the bottom sediments of rice fields (78.1%). farmers and plantation workers will have a greater risk of contracting melioidosis. | 1985 | 4023820 |
| pseudomonas pseudomallei infection from drowning: the first reported case in taiwan. | we report a case of pseudomonas pseudomallei infection, in which the patient acquired the bacteria by aspiration of river water after a drowning incident near manila, the philippines. the pulmonary form of melioidosis was noted at the onset, but septicemia developed at a later stage. positive blood cultures were obtained 17 days after the accident. the patient was treated successfully with a combination of amikacin and cephalothin. this is the first report of p. pseudomallei infection documented ... | 1985 | 4044794 |
| a case comparison of acquired immune deficiency syndrome (aids) in homosexual males with spindle-endothelial cell abnormalities and with recrudescent melioidosis. | the aids syndrome includes cases of biopsy-proven kaposi's sarcoma in persons under 60 years of age, or biopsy- or culture-proven pneumocystis carinii pneumonia, or either of the life-threatening opportunistic infections in young previously healthy persons with no underlying cause of immunodeficiency (center for disease control criteria). here we described the first case of aids with early kaposi's sarcoma-like lesions in homosexual male drug addict and have compared the clinical and laboratory ... | 1985 | 4074477 |
| acute pseudomonas pseudomallei pneumonia and septicemia following aspiration of contaminated water: a case report. | 1985 | 4095613 | |
| [antigenic composition and the serological diagnosis of pseudomonas pseudomallei]. | 1985 | 2412369 | |
| [the polysaccharide component of pseudomonas pseudomallei slime]. | the polysaccharide component contained in the slime of the causative agent of melioidosis was obtained. this component was found to be a biopolymer, mainly of the carbohydrate nature, consisting of galactose, glucose, mannose, rhamnose and two unidentified carbohydrates. the slime polysaccharide component contained two thermostable and acid-resistant antigens. the action of alkali led to the loss of one of these antigens. rabbit antisera to the preparations of the slime polysaccharide component ... | 1985 | 2418606 |
| brain abscess due to pseudomonas pseudomallei. | a brain abscess due to pseudomonas pseudomallei is presented. central nervous system involvement in melioidosis is rare and generally occurs in association with disseminated infection. the importance of early diagnosis and prompt treatment with prolonged antibiotic therapy is emphasised. | 1986 | 3458450 |
| pseudomonas pseudomallei (melioidosis): acute septicemia and meningitis in patient with systemic lupus erythematosus. | 1986 | 3463317 | |
| in vitro susceptibility of strains of pseudomonas pseudomallei isolated in thailand and hong kong to some newer beta-lactam antibiotics and quinolone derivatives. | 1986 | 2934486 | |
| septic melioidosis after a visit to southeast asia. | a case is reported of a fifty-seven year old man with fever, who was admitted to hospital after a recent visit to southeast asia. among the clinical findings prostatitis and broncho-pneumonia were noted. within twenty-four hours irreversible fulminant sepsis developed although he was treated with cefotaxime, tobramycin and erythromycin. post mortem pseudomonas pseudomallei was cultured from blood and aspirate collected by bronchoscopy. it is important to consider melioidosis as a cause of septic ... | 1986 | 3803377 |
| melioidosis in intensive piggeries in south eastern queensland. | the epidemiology of melioidosis was investigated in 8 intensive piggery units which used water from the same river in south eastern queensland. in 3 consecutive years cases of disease followed heavy rainfall and flooding. although pseudomonas pseudomallei was not isolated from water or soil samples the water supply was suspected as the source of infection. affected pigs were detected at slaughter by the presence of abscesses most commonly in the bronchial lymph nodes (40%) and spleen (34%). one ... | 1986 | 3753342 |
| naturally occurring melioidosis in a colonized rhesus monkey (macaca mulatta). | an aged wild-caught male rhesus monkey (macaca mulatta), maintained in a research facility for 10 years, developed bilateral pelvic limb paralysis without other signs of disease. unresponsive to therapy, the monkey was killed and necropsied. chronic inflammation with osteolysis of thoracic vertebrae 10-13 was observed. pseudomonas pseudomallei was cultured and identified from cerebrospinal fluid obtained at the site of the thoracic lesion. this gram-negative bacterium can cause infection in anim ... | 1986 | 3773432 |
| a case of melioidosis presenting with prostatic abscess in hong kong. | melioidosis is endemic in southeast asia but reports of prostatic involvement are rare. we describe a patient with pseudomonas pseudomallei septicemia and a prostatic abscess who presented with signs and symptoms of a urinary tract infection. the organism was cultured from the blood, urine and prostatic pus, and was treated successfully with co-trimoxazole and surgical drainage. genitourinary infection with pseudomonas pseudomallei should be considered in patients from endemic areas, and bacteri ... | 1987 | 3795353 |
| antimicrobial susceptibility of pseudomonas pseudomallei. | 1987 | 3440775 | |
| in-vitro susceptibility of pseudomonas pseudomallei to dna gyrase inhibitors. | 1987 | 2824429 | |
| in-vitro susceptibility of pseudomonas pseudomallei isolated in malaysia to some new cephalosporins and a quinolone. | the current drugs recommended for treatment of melioidosis are tetracycline, chloramphenicol and cotrimoxazole. unfortunately these drugs are not the drug of choice in an acutely ill patient with septicaemia prior to the availability of laboratory results. with the discovery of the new cephalosporins which have a broad spectrum of activity clinicians are using them either alone or in combination with other antibiotics in such critical situations. hence, an in-vitro study was carried out on the s ... | 1987 | 3477872 |
| beta-lactamase of pseudomonas pseudomallei and its contribution to antibiotic resistance. | beta-lactamase production was examined in nine strains of pseudomonas pseudomallei isolated from human, animal and environmental sources in thailand and hong kong. all produced the same weakly inducible, membrane associated chromosomal cephalosporinase, which had a molecular weight of 29,500 and an isoelectric point of 7.4-7.7. the enzyme resembled the cefuroximases of ps. cepacia and proteus vulgaris, but differed from the class i cephalosporinases typical of ps. aeruginosa and most enterobacte ... | 1987 | 3500161 |
| melioidosis: a serological survey in a tuberculosis sanatorium in hong kong. | a serological survey of 275 chinese patients with underlying pulmonary diseases in a tuberculosis sanatorium in hong kong showed that 39 (14%) had haemagglutinating antibody (ha) against pseudomonas pseudomallei in a titre of 1: 80 or above. only 9 of these 39 patients had travelled to endemic areas, suggesting that at least 30 patients (11%) had been exposed to ps. pseudomallei locally. females are affected as often as males, and the seropositive rate is the same whether patients are immunosupp ... | 1987 | 3503401 |
| a competitive immunosorbent assay for detection of pseudomonas pseudomallei exotoxin. | the development of monoclonal antibody and enzyme-linked immunosorbent assay (elisa) techniques has made possible the detection of specific antigens at extremely low concentrations. diagnosis of recalcitrant diseases such as melioidosis depends upon either early isolation and identification of the causative organism or the identification of a specific marker antigen, pseudomonas pseudomallei exotoxin, in serum; the latter is better because it allows more rapid and simple diagnosis. a method of d ... | 1987 | 3585969 |
| subacute pulmonary melioidosis in a temperate climate. | previous reports of cases of melioidosis that were seen in nonendemic areas of australia describe recrudescences of latent infection. we describe the case of a patient who presented in the cooler climate of melbourne with a probable primary, subacute pulmonary infection with pseudomonas pseudomallei. this case illustrates several points that bear consideration in the management of atypical pneumonia and, more specifically, pulmonary melioidosis. historical and occupational clues are easily misse ... | 1987 | 3600459 |
| [automated micromethod for the determination of the utilization of carbon sources by clinically significant pseudomonas species]. | the assimilation of 43 different carbon substrates by 93 clinical strains of pseudomonas aeruginosa was studied by a new miniaturized rapid method. reading of assimilation results was done photometrically after 18-20 h incubation and the resulting data were captured and stored by a microcomputer. the differentiating capacity of the assimilation tests were verified by comparing the results of 41 strains of pseudomonas fluorescens, 48 strains of pseudomonas putida, 52 strains of pseudomonas maltop ... | 1987 | 3118596 |
| susceptibility of pseudomonas pseudomallei to new beta-lactam and aminoglycoside antibiotics. | pseudomonas pseudomallei is resistant to many antimicrobial agents. we determined the susceptibility to twelve beta-lactams and six aminoglycosides of twelve isolates of p. pseudomallei. imipenem (mic range 0.5-1.0 mg/l; mic90 1.0 mg/l), ceftazidime (mic range 1-8 mg/l; mic90 8.0 mg/l), amoxycillin/clavulanate (mic range 4-8 mg/l; mic90 8.0 mg/l), piperacillin (mic range 4-16 mg/l; mic90 8.0 mg/l), and carumonam (mic range 4-16 mg/l; mic90 8.0 mg/l) were the most active. aminoglycosides were rel ... | 1988 | 3162898 |
| neonatal melioidosis: a report of 5 cases. | melioidosis, caused by pseudomonas pseudomallei, occurs in tropical areas and is diagnosed mostly in adults. in khon kaen, a province of northeast thailand, five cases of infantile melioidosis were managed at srinagarind hospital. the patient's specimens were submitted to microbiologic and serologic examination for p. pseudomallei demonstrated by indirect hemagglutination. possible modes of transmission such as environment, perinatal exposure and venereal transmission were investigated. | 1988 | 3174307 |
| melioidosis with brain abscess. | central nervous system involvement in melioidosis is rare. we describe a 48 year old woman who developed septicaemia and a brain abscess due to pseudomonas pseudomallei. since there is a continuing practical problem in bacteriological confirmation of the aetiological agent, diagnosis of melioidosis has to be made on clinical suspicion. | 1988 | 3174527 |
| evaluation of four serological tests for the diagnosis of caprine melioidosis. | a complement fixation (cf) test, 2 indirect haemagglutination (iha-a; iha-l) tests which differed in antigen preparation and technique, and a microtitre agglutination (ma) test were compared in the serodiagnosis of melioidosis in goats. one hundred and eighteen experimental serums and 3143 field serums from goats in endemic and non-endemic areas of north queensland were used in the evaluation. culture of samples for pseudomonas pseudomallei from 112 goats provided substantiating evidence of infe ... | 1988 | 3190597 |
| resistance of pseudomonas pseudomallei to normal human serum bactericidal action. | the effect of human normal serum (hns) on pseudomonas pseudomallei was determined. it is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. ancillary experiments to confirm this serum-resistant property of p. pseudomallei were done by examining the effects of growth phase conditions of the bacteria (i.e., logarithmic and stationary phases) and different buffered systems used as diluent in our bactericidal assay. results obtained showed similar degre ... | 1988 | 3193910 |
| in vitro activities of the newer beta-lactam and quinolone antimicrobial agents against pseudomonas pseudomallei. | imipenem was highly active and bactericidal against all 100 strains of pseudomonas pseudomallei tested, followed in activity by piperacillin, carumonam, ceftazidime, cefotaxime, and ceftriaxone. the addition of clavulanic acid significantly increased the activities of both amoxicillin and ticarcillin. ciprofloxacin and norfloxacin showed poor activity against test strains. | 1988 | 3196005 |
| childhood melioidosis in northeastern thailand. | eighteen cases of childhood melioidosis in northeastern thailand were reviewed. the mean age was 6.8 years with a range from eight months to 15 years. twelve cases (66.7%) had localized melioidosis, six of which had pneumonia. three patients were diagnosed as pharyngocervical melioidosis, the newly recognized syndrome. nine cases (50.0%) had associated diseases including dengue hemorrhagic fever (dhf) in five cases. in all five cases, melioidosis was diagnosed during the convalescent stage as a ... | 1988 | 3227408 |
| characterization of monoclonal antibodies to protein antigen of salmonella typhi. | two monoclonal antibodies were produced against protein antigens of salmonella typhi. one of the antibodies (stp14) belongs to the immunoglobulin g1k subclass, and the other (stp13) was assigned to the immunoglobulin g2a(kappa) subclass. both antibodies could recognize the 34.0-kilodalton protein antigen from s. typhi. the specificity of these antibodies was tested by immunoblotting with a panel of crude protein antigens from 12 bacteria causing enteric fever and enteric fever-like illness: s. t ... | 1988 | 3281976 |
| clinical and pathological observations on goats experimentally infected with pseudomonas pseudomallei. | the effects in goats of the subcutaneous injection of varying doses of pseudomonas pseudomallei (90 to 500,000 bacilli) suspended in normal saline are described. high doses (greater than or equal to 500 bacilli) caused acute, fatal infections. lower doses (90 to 225 bacilli) caused acute or chronic disease when infection became established. however, 11 of 18 goats injected with the lower doses of bacilli showed no sign of infection on clinical or bacteriological examination. response to antibiot ... | 1988 | 3355451 |
| melioidosis: a reminder. | recrudescent pulmonary melioidosis developed in two patients 12 and 16 years after their last travels to an endemic area. in one, a clinically silent prostatic abscess may have been the focus; and in both, the diagnosis was difficult to make even when the laboratory was notified of the possibility of infection with pseudomonas pseudomallei. recrudescent melioidosis should be considered in febrile patients who have been in endemic areas regardless of the interval from last exposure to the develop ... | 1988 | 3364451 |
| [septic melioidosis following a visit to india]. | a case is reported of lethal septicemic melioidosis due to pseudomonas pseudomallei in a 40-year-old woman who had been in india. the epidemiology, clinical findings and management of this unusual disease are discussed. the diagnostic value of serological tests and in vitro sensitivity of pseudomonas pseudomallei to various antibiotics are outlined. melioidosis should be considered in the differential diagnosis of any febrile condition in a person returning from a tropical country. | 1988 | 3375792 |
| [ecological and biological maintenance of sapronoses exemplified by melioidosis]. | the growth and death of pseudomonas pseudomallei, the causative agent of melioidosis, in the soil and the antigenic properties of this microorganism in the soil, in culture media, and in the body of animals have been studied. as revealed in this study, p. pseudomallei can grow in nonsterile soil substrates without the loss of virulence and changes in its antigenic structure. in the body of animals this microorganism rapidly adapts its virulence to host species by the transformation of its antige ... | 1988 | 3389005 |
| activities of five new fluoroquinolones against pseudomonas pseudomallei. | thirty-four isolates of pseudomonas pseudomallei were tested by a broth microdilution technique for susceptibility to amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin. ciprofloxacin was the most active agent tested, with an mic for 90% of the strains tested of 8 micrograms/ml. these in vitro results suggest that the fluoroquinolones tested would not be optimal for therapy of melioidosis. | 1988 | 3415212 |
| [characteristics of the conjugation transfer of the plasmids of p-1-group incompatibility to pseudomonas pseudomallei strains]. | 1988 | 2854878 | |
| antibiotic resistance in pseudomonas pseudomallei. | 1988 | 2896855 | |
| [prospects of the use of chromosomal transformation for the identification of the causative agent melioidosis]. | prospects for the use of chromosomal transformation for the identification of pseudomonas pseudomallei and some other medically important pseudomonas species are considered. the method is simple, reproducible and highly specific. it permits the screening of a great number of cultures and can facilitate further study of the biology of p. pseudomallei and the epidemiology of melioidosis. | 1988 | 3057775 |
| pseudomonas pseudomallei and melioidosis, with special reference to the status in thailand. | melioidosis is a long-known disease since 1912, but only quite recently we have obtained the knowledges about its actual clinical and epidemiological features. the disease is so unique in having a wide spectrum of disease course and clinical manifestation. the causative agent, p. pseudomallei, is free-living bacterium in the natural environments (soil and surface water) of tropical and subtropical areas. just like legionnaires' disease, melioidosis is a good example of infectious disease in whic ... | 1988 | 3075004 |
| [immunomodulating activity of rna mononucleotides]. | the immunological action of rna mononucleotides was studied in animal experiments. the most pronounced activation of macrophagal glycolysis urea cycle, oxidative phosphorylation, lysosomal hydrolases was induced by uridine 5'-monophosphate (5'-ump) and guanosine 5'-monophosphate (5'-gmp); 5'-gmp also induced the maximum increase of the expression of fc gamma receptors. 5'-ump ensured cell activation comparable with the total action of all mononucleotides. 5'-ump and 5'-gmp, used in combination, ... | 1988 | 2452537 |