Publications

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the duration of immunity to plasmodium knowlesi malaria in rhesus monkeys.rhesus monkeys with experimental plasmodium knowlesi infections of varying duration were treated with sodium sulfathiazole to sterilize the infection and after differing lengths of time were reinoculated intraperitoneally with homologous strains of the plasmodium, for the purpose of determining whether there is any acquired immunity to malaria in hosts from whom all parasites have been removed. two monkeys, one receiving sulfathiazole on the 2nd day of acute infection and the other on the 4th da ...194419871378
poliomyelitis in the cynomolgus monkey : iii. infection by inhalation of droplet nuclei and the nasopharyngeal portal of entry, with a note on this mode of infection in rhesus.1. poliomyelitis virus suspensions were atomized so as to produce dry droplet nuclei which, suspended in air, were introduced into a special infecting chamber and inhaled by test animals, both rhesus and cynomolgus monkeys. 2. without olfactory blockade, 5 of 7 rhesus and 6 of 7 cynomolgus monkeys developed poliomyelitis of the cns with entry through the olfactory nerves. 3. with olfactory blockade, 2 of 35 rhesus and 4 of 10 cynomolgus monkeys developed this form of the disease by routes proved ...194419871397
poliomyelitis by accidental contagion in the chimpanzee.poliomyelitis virus was isolated from the stools of two uninoculated chimpanzees which had been quartered for 6 months in cages adjoining those of rhesus monkeys receiving intranasal inoculations of potent human stools. upon arrival, and for 4 months thereafter, neither chimpanzee had antibody against the virus eventually isolated from it. however, antibody had developed against the animals' own virus strains at the time these were isolated from the feces.194419871425
the placental gonadotrophin and luteal function in monkeys (macaca mulatta). 194421434185
maintenance and restoration of spermatogenesis in hypophysectomized rhesus monkeys by androgen administration. 194421434199
the effect of hypothyroidism on menstruation in adult rhesus monkeys. 194421434206
toxoplasmosis in the monkey; acute fatal infection experimentally produced in a young macaca mulatta. 194521003564
the question of the transmission of poliomyelitis in rhesus monkeys by accidental laboratory infection. 194521005130
reactions of a rhesus monkey to embalmed corpses. 194521014228
knowlesi malaria in monkeys; microscopic pathological circulatory physiology of rhesus monkeys during acute plasmodium knowlesi malaria. 194521016051
studies in rodent poliomyelitis : vi. further observations on interference between murine and simian strains of poliomyelitis virus.1. attempts to separate by processes of physical segregation, i.e. ultrafiltration, ultracentrifugation, or dialysis, from live sk murine poliomyelitis virus a non-pathogenic agent capable of interfering with simian poliomyelitis virus were unsuccessful. neither was it possible to convert live sk murine virus into a non-pathogenic interfering agent by processes of chemical inactivation, i.e., phenolization or formalinization. 2. preparations of sk murine virus, which had been markedly attenuated ...194519871457
immunization of rhesus monkeys against malarial infection (p. knowlesi) with killed parasites and adjuvants. 194517787140
poliomyelitis virus in fly-contaminated food collected at an epidemic.poliomyelitis virus has been detected in food exposed to flies at homes of poliomyelitis patients within an epidemic area. this was achieved by feeding such exposed food to chimpanzees which developed subclinical infections or asymptomatic carrier states ascertained by positive stool tests in rhesus monkeys.194517735530
rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of brain tissue with adjuvants.rapid production in the monkey of a pathological condition resembling acute disseminated encephalomyelitis, marked by demyelination, can be achieved by the use of adjuvants added to rabbit brain emulsions.194617780100
reactions of monkeys to experimentally induced influenza virus a infection : an analysis of the relative roles of humoral and cellular immunity under conditions of optimal or deficient nutrition.1. macaca mulatta monkeys on a normal diet have proved resistant to intranasal but not to intratracheal inoculation of influenza virus. 2. neutralizing antibodies appeared 8 to 10 days after inoculation with either living or heat-inactivated virus. the antibodies were noted to be still present as long as 9 months after infection with living virus. 3. a specific granulopenic leucopenia characteristically followed primary influenza virus inoculation, regardless of altered conditions of diet, expos ...194619871557
type-specific protection and immunity following intranasal inoculation of monkeys with group a hemolytic streptococci.1. nasopharyngeal carrier states of several weeks to several months duration were induced in the macaca mulatta by the intranasal inoculation with matt strains of group a streptococci. 2. following such a successful inoculation with a particular type of group a streptococcus, the animal was usually resistant to reimplantation with that same type for several months to a year or more, although reimplantation with a heterologous type could generally be easily effected. 3. this resistance was shown ...194619871558
reactions of monkeys to experimentally induced streptococcus hemolyticus, group c, infection : an analysis of the relative roles of humoral and cellular immunity under conditions of optimal or deficient nutrition.macaca mulatta on a normal diet proved to be resistant on intranasal inoculation with streptococcus hemolyticus, group c. more than half of the monkeys maintained for various periods on a modified dietary regimen deficient in vitamin b became more or less anemic. all developed a granulopenic leucopenia during which many developed spontaneous infections, and all were extremely susceptible on intranasal instillation of streptococcus hemolyticus, group c. in normal monkeys, primary inoculation with ...194619871569
studies on malarial parasites : vi. the chemistry and metabolism of normal and parasitized (p. knowlesi) monkey blood.1. normal monkey, macaca mulatta, plasma and red cells are similar in their inorganic composition to those of human beings. inorganic phosphate values of plasma and red cells from parasitized monkey blood are lower than normal. plasma potassium values are higher than normal particularly during segmentation. other inorganic components of parasitized blood show little variation from normal. 2. monkey red blood cells parasitized with p. knowlesi consume oxygen in the presence of glucose, lactate, g ...194619871589
experimental studies in cardiovascular pathology: xiv. experimental atheromatosis in macacus rhesus monkeys. 194619970910
the performance of rhesus monkeys on series of object-quality and positional discriminations and discrimination reversals. 194621018301
a comparison of the tactile areas in the cerebellum of the cat and monkey (macaca mulatta). 194621020624
dental caries in the rhesus monkey. 194621022320
respiration in macaca mulatta (rhesus monkey). 194621024171
cutaneous distribution of peripheral nerves in rhesus monkeys as determined by the electrical skin resistance method. 194621026523
chemotherapy of plasmodium knowlesi infections in macaca mulatta monkeys. 194620983207
studies on pyridoxine deficiency in rhesus monkeys. 194620984563
hyperplasia of the thyroid gland of rhesus monkeys after thiouracil treatment. 194620988411
a study of pyridoxine and pantothenic acid deficiencies in the monkey (macaca mulatta). 194620989627
ulnar-femoral nerve anastomosis in paraplegic rhesus monkey. 194620993159
attempts to produce a niacin deficiency in the rhesus monkey. 194620993757
chemotherapy of plasmodium knowlesi infections in macaca mulatta monkeys. 194620994722
rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of brain tissue with adjuvants. 194620999821
studies of plasmodium cynomolgi in the rhesus monkey, macaca mulatta. 194621003024
distribution of carbonic anhydrase in the pallium of rhesus monkey and man as compared with that of lower mammals. 194621064589
the argentaffin cells of the digestive tract of the monkey (macaca mulatta). 194621066168
cutaneous distribution of superficial radial nerve in rhesus monkeys as determined by the electrical skin resistance method. 194621066211
non-essentiality of hypophysis for maintenance of pregnancy in rhesus monkeys. 194621066262
spinal projections of brainstem in rhesus monkey deduced from retrograde chromatolysis. 194621066278
the mammalian midbrain and isthmus regions; the fiber connections; the relations of the tegmentum of the midbrain with the basal ganglia in macaca mulatta. 194620999132
the influence of folic acid deficiency in macaca mulatta on susceptibility to experimental poliomyelitis. 194620994875
the influence of "folic acid" deficiency in macaca mulatta on susceptibility to experimental poliomyelitis. 194616561138
a study of chemotherapy in experimental bacillary dysentery of macaca mulatta with emphasis on clearing of the carrier state. 194621016043
differences among strains of poliomyelitis virus in macaca mulatta. 194621011563
sarcocystis in macaca mulatta. 194720294089
extirpation of the cortical arm area as defined by stimulation under conditions of primary facilitation (macaca mulatta). 194720293601
distribution of cortical potentials evoked by electrical stimulation of dorsal roots in macaca mulatta. 194720342929
corticocortical connections of the superior surface of the temporal operculum in the macaque (macaca mulatta). 194720342887
leucocytes in normal rhesus monkeys. 194729014873
the rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of heterologous and homologous brain tissue with adjuvants.1. a picture resembling acute disseminated encephalomyelitis in the human being has been regularly and rapidly produced in rhesus monkeys by injection of emulsions of adult rabbit and monkey brain administered with adjuvants. 2. no lesions of the central nervous system resulted from injection of similar emulsions of fetal rabbit brain or adult rabbit lung. 3. a description of the gross and histological findings in the central nervous system is given and compared with features of human demyelinat ...194719871595
reactions of monkeys to experimental mixed influenza and streptococcus infections : an analysis of the relative roles of humoral and cellular immunity, with the description of an intercurrent nephritic syndrome.1. the vital importance of the cellular defense forces in the resistance of the monkey to combined streptococcus and influenza virus infections has been demonstrated. 2. some of the conditions prejudicial to the maintenance of an optimum cellular reserve in the infected animal have been revealed; viz., undernutrition, physical cold, intratracheal route of infection. 3. the potential threat exerted by latent foci of streptococci, and the importance, in relation to the combined infection with viru ...194719871608
multiplication and spread of the virus of st. louis encephalitis in mice with special emphasis on its fate in the alimentary tract.1. beginning at 24 hours after intravenous injection of about 10 million intracerebral ld(50) of virus there was evidence of simultaneous, progressive multiplication in the brain and intestinal tract. 2. when the virus was introduced directly into the brain or the nasal cavities and mouth, none was found in the intestinal tract until there was general centrifugal spread from the central nervous system during the last stages of the infection at 96 or 120 hours after inoculation when the virus in ...194719871641
the susceptibility of infant rhesus monkeys to poliomyelitis virus administered by mouth : a study of the distribution of virus in the tissues of orally infected animals.although rhesus monkeys have been generally regarded as refractory to infection with poliomyelitis virus administered by the oral route, two of seven infant rhesus developed paralytic poliomyelitis when fed murine-adapted strains of virus. preliminary intranasal treatment with zinc sulfate and negative serial sections of the olfactory bulbs of the positive animals ruled out the possibility that infection occurred by way of the olfactory pathway. studies on the distribution of virus in the tissue ...194719871680
cortical connections of parietal and frontal opercula in the monkey (macaca mulatta). 194720244157
removal of the corpus luteum and of the ovaries of the rhesus monkey during pregnancy; observations and cautions. 194720255047
a topographical atlas of the brain-stem of the rhesus monkey. 194720258880
histological appearance of coiled arterioles in the endometrium of rhesus monkey, baboon, chimpanzee and gibbon. 194720266322
the pathology of acute disseminated encephalomyelitis produced experimentally in the rhesus monkey and its resemblance to human demyelinating disease. 194720267714
osteogenesis following fenestration of the vestibular labyrinth of the rhesus monkey; a controlled experimental study. 194720268767
an adaptation of the dosimetric method for use in smaller animals; the retained median lethal dose and the respiratory response in normal, unanesthetized rhesus monkeys (macaca mulatta) exposed to phosgene. 194720278378
asexual reproduction of plasmodium cynomolgi in rhesus monkeys. 194720283800
the structure and mechanical functioning of the living liver lobules of frogs and rhesus monkeys. 194720287326
the effect of diet on the hemoglobin, erythrocyte, and leukocyte content of the blood of the rhesus monkey (macaca mulatta). 194720288052
the vascular pattern of the endometrium of the pregnant rhesus monkey. 194720289377
localization of motor cells in the thoracic spinal cord of the rhesus monkey. 194720289387
specialized argyrophilic (argentaffine?) cells in the anal canal of the rhesus monkey. 194720290935
changes in the electrophoretic pattern of the plasma proteins of monkeys (macaca mulatta). 194720343416
experimental thiamine deficiency in the rhesus monkey. 194720344717
autolyzed brain tissue as a means of facilitating transmission of experimental poliomyelitis.autolyzed brain tissue diluent shortens the incubation period and facilitates the transfer of poliomyelitis virus to cfw swiss mice, hamsters, and rhesus monkeys. the leon monkey-passage strain of poliomyelitis virus was successfully adapted to cfw swiss mice by means of this technic. since this manuscript was submitted we have isolated several strains of poliomyelitis virus from infected human feces and spinal cord in cfw swiss mice by means of this technic.194717843383
a comparison of the growth of the ovum and follicle in normal rhesus monkeys, and monkeys treated with oestrogens and androgens. 194718919786
histologic appearance of coiled arterioles in the endometrium of rhesus monkey, baboon, chimpanzee, and gibbon. 194818932373
structure and repair of the olfactory mucosa in rhesus monkeys. 194818932641
experimental studies on acute disseminated encephalomyelitis in the rhesus monkey. 194818856255
xanthurenic acid excretion in pyridoxine deficient rhesus monkeys. 194818856444
corticocortical connections of the superior surface of the temporal operculum in the monkey, macaca mulatta. 194818865006
corticocortical connections of the superior bank of the sylvian fissure in the monkey, macaca mulatta. 194818865007
the chemical cytology of the chorioid plexus and blood brain barrier of the rhesus monkey, macaca mulatta. 194818866774
poliomyelitis in an uninoculated rhesus monkey, and in orally inoculated monkeys, receiving desoxypyridoxine. 194818872698
microscopic observations of intravascular agglutination of red cells and consequent sludging of blood in rhesus monkeys infected with knowlesi malaria. 194818882486
failure of prostigmin to affect uterine bleeding in the rhesus monkey. 194818882817
attempts to produce cancer in rhesus monkeys with carcinogenic hydrocarbons and estrogens. 194818884340
studies on acute disseminated encephalomyelitis produced experimentally in rhesus monkeys.the factor in brain tissue which induces acute disseminated encephalomyelitis, when injected into rhesus monkeys as an emulsion with adjuvants, has been found in human, monkey, rabbit, and chicken brain but is absent from frog and fish brain. it is unaffected by fixation of the brain in formalin, by boiling, and by treatment with ultrasound. it is present in the spinal cord of 3 day old rabbits but does not appear in the rabbit cerebrum until about the 12th day of life; in this respect it parall ...194818884901
the relationship of pars tuberalis to pars distalis in the hypophysis of the rhesus monkey. 194818886017
neurotoxicity of the 8-aminoquinolines; lesions in the central nervous system of the rhesus monkey induced by administration of plasmocid. 194818889209
corticocortical connections of the cerebral cortex lying within the arcuate and lunate sulci of the monkey, macaca mulatta. 194818889213
thiamin deficiency in the rhesus monkey; clinical, metabolic and hematologic observations. 194818893857
a second motor cortex in the monkey, macaca mulatta. 194818915134
a study of motor cell localization in the spinal cord of the rhesus monkey. 194818919561
the distribution of the anterior commissure in the monkey, macaca mulatta. 194818103780
paresthesia in a rhesus monkey associated with a thalamic lesion, and its alleviation by post-central cortical excision. 194918108337
the effect of hypophysectomy upon the permanent dentition of rhesus monkeys. 194918110505
chorio-meningoencephalitis following inoculation of newcastle disease virus in rhesus monkeys. 194918112781
studies on acute disseminated encephalomyelitis produced experimentally in rhesus monkeys; disseminated encephalomyelitis produced in monkeys with their own brain tissue.acute disseminated encephalomyelitis has been produced in rhesus monkeys by injection of their own brain tissue, removed surgically and incorporated with adjuvants.194918113912
exoerythrocytic stages of plasmodium cynomolgi in the macaca mulatta. 194918124332
acute occlusion by ligature of the portal vein in the macacus rhesus monkey. 194918128990
observations on the cervical mucosa of the rhesus monkey. 194918130384
the vascular pattern of the endometrium of the pregnant rhesus monkey (macaca mulatta). 194918130386
effect of experimental thiamine deficiency on the nervous system of the rhesus monkey. 194918135508
studies on the subthalamus of the rhesus monkey; anatomy and fiber connections of the subthalamic nucleus of luys. 194918136717
studies on the subthalamus of the rhesus monkey; hyperkinesia and other physiologic effects of subthalamic lesions; with special reference to the subthalamic nucleus of luys. 194918136718
asexual reproduction of plasmodium knowlesi in rhesus monkeys. 194918137136
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