Publications

impact of periodontal therapy on the subgingival microbiota of severe periodontitis: comparison between good responders and individuals with refractory periodontitis using the human oral microbe identification microarray.	this study compares the changes to the subgingival microbiota of individuals with "refractory" periodontitis (rp) or treatable periodontitis (good responders [gr]) before and after periodontal therapy by using the human oral microbe identification microarray (homim) analysis.	2012	22324467
a novel selective medium for the isolation and distribution of rothia dentocariosa in oral cavities.	rothia dentocariosa is an indigenous microbial flora of dental plaque. to examine the bacterium population in oral cavities, a novel selective medium, designated rdsm, was developed for the isolation of r. dentocariosa. rdsm was prepared by adding 0.5 μg/ml of lincomycin, 10 μg/ml of colistin, and 40% sucrose to heart infusion (hi). average growth recovery of r. dentocariosa on rdsm was 93.8% that of hi medium. growth of other bacteria including rothia mucilaginosa, neisseria, actinomyces, or st ...	2012	22796060
shifts in the microbial population in relation to in situ caries progression.	the shift in microbial diversity from young to mature plaque, related to caries activity on sound and restored surfaces, was studied using denaturing gradient gel electrophoresis. during a 20-week in situ study on caries progression 8 subjects wearing restored and unrestored dentin and enamel sections, biofilm was sampled after 1 and 20 weeks (young or mature plaque). a higher microbial diversity (mature plaque) was seen in caries-active compared to caries-free subjects. rothia dentocariosa and ...	2012	22739571
rothia dentocariosa repeat and relapsing peritoneal dialysis-related peritonitis: a case report and literature review.	peritonitis is well recognized as the achilles tendon of peritoneal dialysis (pd). reoccurrence of peritonitis due to the same organism, defined as either repeat or relapsing peritonitis under the 2005 guidelines by the international society for peritoneal dialysis, often results in pd technique failure. rothia dentocariosa, a low-virulent human oropharynx commensal, is a rarely reported pathogen in human infection, particularly infective endocarditis. r. dentocariosa pd-related peritonitis is e ...	2012	22506572
the predominant bacteria isolated from radicular cysts.	to detect predominant bacteria associated with radicular cysts and discuss in light of the literature.	2013	24011184
bacterial community development in experimental gingivitis.	current knowledge of the microbial composition of dental plaque in early gingivitis is based largely on microscopy and cultural methods, which do not provide a comprehensive description of oral microbial communities. this study used 454-pyrosequencing of the v1-v3 region of 16s rrna genes (approximately 500 bp), and bacterial culture, to characterize the composition of plaque during the transition from periodontal health to gingivitis. a total of 20 healthy volunteers abstained from oral hygiene ...	2013	23967169
voice prosthetic biofilm formation and candida morphogenic conversions in absence and presence of different bacterial strains and species on silicone-rubber.	morphogenic conversion of candida from a yeast to hyphal morphology plays a pivotal role in the pathogenicity of candida species. both candida albicans and candida tropicalis, in combination with a variety of different bacterial strains and species, appear in biofilms on silicone-rubber voice prostheses used in laryngectomized patients. here we study biofilm formation on silicone-rubber by c. albicans or c. tropicalis in combination with different commensal bacterial strains and lactobacillus st ...	2014	25111806
probing of microbial biofilm communities for coadhesion partners.	investigations of interbacterial adhesion in dental plaque development are currently limited by the lack of a convenient assay to screen the multitude of species present in oral biofilms. to overcome this limitation, we developed a solid-phase fluorescence-based screening method to detect and identify coadhesive partner organisms in mixed-species biofilms. the applicability of this method was demonstrated using coaggregating strains of type 2 fimbrial adhesin-bearing actinomyces and receptor pol ...	2014	25107971
anti-biofilm and antibacterial activities of zinc oxide nanoparticles against the oral opportunistic pathogens rothia dentocariosa and rothia mucilaginosa.	species of the genus rothia that inhabit the oral cavity have recently been implicated in a number of diseases. to minimize their role in oral infections, it is imperative to reduce and/or control the growth and biofilm formation activity of rothia spp. in this study, two bacterial isolates, ora-7 and ora-16, were obtained from the oral cavity of a healthy male subject and identified as rothia dentocariosa and rothia mucilaginosa, respectively, using a polyphasic taxonomic approach. antimicrobia ...	2014	25311638
a case of rothia dentocariosa bacteremia in a patient receiving infliximab for ulcerative colitis.		2014	24496430
rothia dentocariosa induces tnf-alpha production in a tlr2-dependent manner.	previous work suggested that rothia dentocariosa is associated with periodontal inflammatory disease. however, little is known about the pathogenicity of this bacterium. to characterize host response to this bacterium, we measured (via elisa) the amount of tnf-α in the culture supernatant following the stimulation of thp-1 cells (a human acute monocytic leukemia cell line) with r. dentocariosa cells (atcc14189 and atcc14190). exposure to bacterial cells induced the production of tnf-α in a dose- ...	2014	24265267
prosthetic hip joint infection caused by rothia dentocariosa.	rothia dentocariosa is an aerobic, pleomorphic, catalase-positive, non-motile, gram-positive bacteria that is a part of the normal flora in the oral cavity and respiratory tract. although it is a rare cause of systemic infection, it may be observed in immunosuppressed individuals. here we report the case of an 85-year old man who developed prosthetic joint infection that was caused by r. dentocariosa after hemiarthroplasty. this is the first case report of a prosthetic hip joint infection caused ...	2015	26379996
rothia dentocariosa: a rare cause of left-sided endocarditis in an intravenous drug user.		2015	26241376
the oral mucosal and salivary microbial community of behçet's syndrome and recurrent aphthous stomatitis.	behçet's syndrome (bs) is a multisystem immune-related disease of unknown etiology. recurrent aphthous stomatitis (ras) is characterized by the presence of idiopathic oral ulceration without extraoral manifestation. the interplay between the oral microbial communities and the immune response could play an important role in the etiology and pathogenesis of both bs and ras.	2015	26037240
salivary microbiome diversity in caries-free and caries-affected children.	dental caries (tooth decay) is an infectious disease. its etiology is not fully understood from the microbiological perspective. this study characterizes the diversity of microbial flora in the saliva of children with and without dental caries. children (3-4 years old) with caries (n = 20) and without caries (n = 20) were recruited. unstimulated saliva (2 ml) was collected from each child and the total microbial genomic dna was extracted. dna amplicons of the v3-v4 hypervariable region of the ba ...	2016	27898021
differential utilization of basic proline-rich glycoproteins during growth of oral bacteria in saliva.	although saliva is widely recognized as a primary source of carbon and nitrogen for growth of the dental plaque biofilm community, little is known about how different oral bacteria utilize specific salivary components. to address this question, 32 strains representing 16 genera commonly isolated from early plaque biofilms were compared for growth over two transfers in stimulated (by chewing parafilm) whole saliva that was stabilized by heat treatment and dialysis. the cell densities, measured by ...	2016	27316966
long-term antibiofilm activity of carboxymethyl chitosan on mixed biofilm on silicone.	silicone voice prostheses are most frequently used in voice rehabilitation of laryngectomized patients. however, the functional device lifetimes are limited due to formation of mixed biofilms. existing in vitro models simulating biofilm formation are restricted to only short-term periods.	2016	27346839
mitral endocarditis due to rothia aeria with cerebral haemorrhage and femoral mycotic aneurysms, first french description.	rothia aeria is a rothia species from the micrococcaceae family. we report here the first french r. aeria endocarditis complicated by brain haemorrhage and femoral mycotic aneurysms. altogether, severity and antimicrobial susceptibility should make us consider the management of r. aeria endocarditis as staphylococcus aureus methicillin-susceptible endocarditis.	2016	27408740
rothia dentocariosa endocarditis: an especially rare case in a previously healthy man.	rothia dentocariosa is a rare gram-positive bacterial organism, one of the group of microbes that normally resides in the mouth and respiratory tract. r. dentocariosa rarely causes disease. documented cases occur chiefly in patients with valvular or dental disease, or both. we report the case of a previously healthy 58-year-old man who presented with evidence of bacterial endocarditis caused by this organism-which originated from an elusive source. his endocarditis was successfully treated with ...	2016	27303245
isolation and identification methods of rothia species in oral cavities.	rothia dentocariosa and rothia mucilaginosa which are gram-positive bacteria are part of the normal flora in the human oral cavity and pharynx. furthermore, rothia aeria, which was first isolated from air samples in the russian space station mir, is predicted to be an oral inhabitant. immunocompromised patients are often infected by these organisms, leading to various systemic diseases. the involvement of these organisms in oral infections has attracted little attention, and their distribution i ...	2017	28082174