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[skin infections caused by mycobacterium marinum: 5 cases]. 1979525200
granulomatous synovitis: the role of atypical mycobacteria.clinical data on 25 patients with granulomatous synovitis and bursitis observed from 1970 through 1977 are reviewed. the lesions occurred about the extremities, the wrists and hands being involved most often. with three exceptions, the patients had no significant underlying disease. the lesions were chronic and often followed minor trauma. many patients had had prior surgery, steriod injections, or both. at the time of surgery for the synovitis, the gross appearance proved to be relatively chara ...1979542760
[cutaneous mycobacteriosis of aquaria. a disease transmitted from fish to man].the authors refer about one case of cutaneous infection from mycobacterium marinum transmitted to man from tropical fishes of a fish tank. the authors describe the lesions produced by mycobacterium in man and in fish, as well as the relevant hystological findings and the microbiological enquiries carried out for isolation and typing. the possibility of direct transmission of a tubercular infection from fish to man has been demonstrated. the authors think it to be useful a careful sanitary contro ...1979553524
[minocycline hydrochloride treatment for mycobacterium marinum infection of the skin. (author's transl)]. 19806966697
fish tank granuloma.a case of fish tank granuloma is presented. a lesional biopsy sample yielded growth of mycobacterium marinum on löwenstein's medium. treatment with cotrimoxazole was successful.19806162325
aquarium-borne mycobacterium marinum granulomas.mycobacterium marinum was isolated for the first time in denmark from skin granuloma of a 37-year-old man. the skin lesion was provoked by an injury from the broken glass of an aquarium used for tropical fish. treatment with rifampicin and ethambutol was successful. at the time of diagnosis, m. marinum was also isolated from a dead fish; but in no case was skin granuloma found among purchasers of fish supplied by the patient.19807189291
[cutaneous infection with mycobacterium marinum]. 19807190745
response in distant lymph nodes of mice to infection in the hind footpad with mycobacterium marinum.in an attempt to demonstrate the importance of the popliteal lymph node in limiting the progress of infection with mycobacterium marinum in the hind footpads of c57bl mice, such infections were studied in mice subjected to popliteal or popliteal and inguinal adenectomies. in the absence of the popliteal node, the footpad infection was only slightly enhanced compared with infections of sham-operated control mice; the inguinal node was found to be greatly enlarged and appeared to have substituted ...19807380564
survival of balb/c mice after intravenous infection with mycobacterium marinum.in a search for a simple technique by which to study the disease of mice that follows infection with mycobacterium marinum, survival of balb/c mice after i.v. inoculation of m. marinum was measured. length of survival was inversely proportional to the number of viable organisms in the inoculum, and was greater in weanling than in yearling mice. prior infection with m. marinum in a hindfoot pad at least two weeks before i.v. challenge with the same organism conferred protection against the challe ...19807399878
tuberculosis in marine tropical fishes in an aquarium.skin, gill and visceral tubercle lesions were detected in marine tropical fish in an aquarium. ninety-seven fish of 17 different genera were affected. the tubercles consisted of a wall of densely packed epithelioid cells and necrotic center packed with acid-fast bacilli identified as mycobacterium marinum.19807431514
heat treatment for certain chronic granulomatous skin infections.four cases of chronic granulomatous skin infections (two due to sporothrix schenckii and two to mycobacterium marinum) were treated primarily by the intermittent application of local hyperthermia. this treatment was initiated either because of intolerance to conventional iodide therapy for sporotrichosis or as interim therapy while awaiting diagnosis of the mycobacterial infections. the response indicated that the application of heat is a useful adjunct to the therapy of these infections. our ex ...19807444542
in vitro susceptibility of mycobacterium marinum to eight antimicrobial agents.the in vitro susceptibilities of 16 mycobacterium marinum strains to eight antimicrobial agents were determined by the agar dilution technique. the most active drugs were amikacin and kanamycin. tetracycline, doxycycline, and minocycline were inhibitory, predominantly at concentrations slightly below the expected blood and tissue levels. trimethoprim-sulfamethoxazole and erythromycin demonstrated activity only at concentrations greater than those usually attained in serum and tissues. gentamicin ...19807447416
protection of mice by intraperitoneal vaccination against challenge in the foot pad with mycobacterium marinum.in a study of local infection of mice with mycobacterium marinum, heat-killed m. marinum suspended either in hanks' balanced salt solution or in freund's incomplete adjuvant was administered i.p. to balb/c mice. the mice were challenged in the hind foot pad 3, 7, or 14 days thereafter with 5 x 10(3) viable m. marinum. at every time interval, killed m. marinum in the saline medium conferred modest protection against the challenge infection, whereas the antigen suspended in adjuvant conferred prot ...19807451112
sporotrichoid mycobacterium marinum skin infection treated with minocycline hydrochloride. 19807471467
["swimming-pool granuloma"--an infection of skin with mycobacterium marinum (author's transl)].a typical case of infection with mycobacterium marinum is demonstrated. mycobacterium marinum, the symptoms and signs of infection and the way of treatment are shown.19817222879
response in the hindfoot pad and popliteal lymph node of c57bl mice to infection with mycobacterium marinum.c57bl mice inoculated in the hindfoot pads with 5 x 10(3) viable mycobacterium marinum developed a localized disease process, characterized by swelling of the foot and increases in the number of acid-fast bacilli and colony forming units recovered. these changes became maximal 10 to 14 days after inoculation and then decreased in intensity. an acute inflammatory response appeared in the hindfoot pad during the first 24 h and increased in intensity during the next few days. by seven days after in ...19817239868
mycobacterium marinum infection in bufonidae. 19817253098
relationship between photochromogenicity and test temperature in mycobacteria.although it has been recommended that photochromogenicity of mycobacteria should be tested after incubation at 25 to 30 degrees c for 2 weeks (wayne et al., int. j. syst. bacteriol. 24:412-419, 1974), our results indicate that photochromogenicity should be determined at 37 degrees c in the dark and under continuous exposure to light for 2 weeks. the test at 37 degrees c gives more stable results for mycobacterium kansasii, mycobacterium marinum and mycobacterium szulgai.19817276150
susceptibility of mycobacterium marinum to tetracyclines and aminoglycosides.current agar dilution methods for susceptibility testing of mycobacterium marinum versus the tetracyclines have failed to show in vitro susceptibility despite good in vivo results. we found that the tetracyclines were unstable in agar and resulted in a fine haze of growth for several concentrations before complete inhibition of growth was seen. in contrast, the aminoglycosides resulted in sharp minimal inhibitory concentration endpoints, which were generally independent of the length of incubati ...19817325629
recent experience in the epidemiology of disease caused by atypical mycobacteria.to obtain information on the epidemiology of mycobacteriosis, water and air samples collected along the east coast of the united states were examined for mycobacteria. mycobacterium avium-intracellulare-scrofulaceum (mais) were isolated from 25% of the water, samples, mostly those from south carolina, georgia, and the gulf states. mycobacterium kansasii and mycobacterium marinum were not found, probably because of the detrimental effects of the naoh used to decontaminate the samples. mais strain ...19817339831
role of the popliteal lymph node in infection with mycobacterium marinum of the hind footpad of the mouse, and source of the cells that characterize the process.we examined the possibility that the popliteal lymph node serves as the source of the lymphocytes that, together with macrophages, characterize the lesion produced by infection with mycobacterium marinum in the hind footpad of the mouse. naïve mice were partially protected against challenge with m. marinum in the hind footpad by intravenous infusion of lymphocytes harvested from the popliteal nodes of donor mice infected with m. marinum 7 days earlier. lymphocytes harvested from the popliteal no ...19817345563
disseminated mycobacterium marinum infection after renal transplantation. 19817011140
the effect of body temperature and cell-mediated immunity on the growth of mycobacterium marinum and mycobacterium leprae in mice.evidence is presented that the high susceptibility of armadillos to infection with mycobacterium leprae cannot be explained solely in terms of body temperature because mutant mice maintained with a body temperature similar to that of armadillos do not become heavily infected with m. leprae. the depression of cell-mediated immunity accompanying the low body temperature is not sufficient to produce an overwhelming infection. the results obtained with m. marinum suggest that whereas lack of cell-me ...19817031255
mycobacterium marinum tenosynovitis in a long island fisherman. 19816942253
mycobacterium marinum infection. a fishy story. 19827062549
in vitro activity of trimethoprim and sulfamethoxazole against the nontuberculous mycobacteria.trimethoprim (tmp) and sulfamethoxazole (smz) were studied alone and in combination (tmp-smz) against 141 nontuberculous mycobacteria; an agar dilution method was used. all strains of mycobacterium kansasii (8), mycobacterium marinum (16), and mycobacterium scrofulaceum (3); 97% (63 of 65) of strains of mycobacterium fortuitum; and 27% (3 of 11) of strains of mycobacterium avium-intracellulare were inhibited by less than or equal to 32 micrograms of smz/ml. in contrast, all 38 isolates of mycoba ...19827111959
mycobacterium marinum infections: diagnosis and treatment. 19827146965
[apropos of the 2nd case of cutaneous granuloma caused by mycobacterium marinum in uruguay].a new, second uruguayan case of cutaneous granuloma by mycobacterium marinum is presented. the patient a 31 years old white man from montevideo city had two granulomatous and ulcerated lesions on the right knee, secondary to wounds suffered with mussels' shells 5 years before while cleaning his boat in saline waters close to our rio de la plata river. diagnosis was made by finding the typical acid fast organisms in the lesions, the isolation of the agent in cultures and through experimental inoc ...19826764231
disseminated cutaneous mycobacterium marinum infection. 19836824363
[change in cell-mediated immunity to mycobacterium leprae and mycobacterium marinum in hansen's disease patients].the cell mediated immunity (cmi) to protein purified derivates of mycobacterium leprae, mycobacterium tuberculosis, mycobacterium avium and mycobacterium marinum was studied. leukocyte migration inhibition (lmi) and delayed hypersensitivity skin reactions to these antigens were examined in 44 hanseniasis patients (20 quiescent virchowians, 13 reactional virchowians and 11 tuberculoid patients) and 15 healthy subjects. an impairment in lmi and delayed hypersensitivity tests to m. leprae and m. ma ...19836432692
[in vitro susceptibility of mycobacterium marinum to amikacin sulfate]. 19836620633
mycobacterium marinum infection of the hand involving deep structures.five patients with mycobacterium marinum infection of the hand involving deep structures were seen recently. four of them were fishermen. hydrocortisone injection or simple incision and drainage led to worsening of the infection. the clinical presentation, operative finding, and histopathologic and microbiologic features were quite similar in all five patients. extensive debridement and therapy with ethambutol and rifampin led to satisfactory results in four patients while biopsy and therapy in ...19836630930
systemic mycobacterium marinum infection in a european hedgehog. 19836643246
agar disk elution method for susceptibility testing of mycobacterium marinum and mycobacterium fortuitum complex to sulfonamides and antibiotics.an agar disk elution method using round well plates, supplemented mueller-hinton agar, and commercial drug disks is described for susceptibility testing of mycobacterium marinum and the rapidly growing mycobacteria to antibiotics and sulfonamides. by this method, 14 of 14 strains of m. marinum were susceptible to rifampin, doxycycline, minocycline, and trimethoprim-sulfamethoxazole. identical results were obtained with middlebrook 7h10 agar and drugs prepared from standard powders. with 58 isola ...19836651277
[infection with mycobacterium marinum from an aquarium].clinical, histological and electron microscopical findings of swimming pool granuloma in a 19-year-old soldier are demonstrated. isolation of mycobacterium marinum and positive tests with the "marinum sensitin" confirmed diagnosis. problems of treatment are discussed.19836662729
[in vitro susceptibility of mycobacterium marinum to st preparation (sulfamethoxazole-trimethoprim)]. 19836663794
effects of treatment with muramyl dipeptide on resistance to mycobacterium leprae and mycobacterium marinum infection in mice.studies were carried out to determine whether treatment of mice with the synthetic adjuvant muramyl dipeptide (mdp) afforded resistance to infection with mycobacterium leprae or m. marinum in mice. regardless of the timing, dose, or route of administration, there was no evidence that treatment with mdp or 3 of its analogs (desmdp, abumdp, valmdp) enhanced resistance to food pad infection with m. leprae or m. marinum. in parallel studies, systemic treatment with propionibacterium acnes failed to ...19836343295
cutaneous infections: microbiologic and epidemiologic considerations.the normal bacterial flora of the skin represents an important host defense mechanism against invasion by potentially pathogenic organisms. this flora is primarily composed of aerobic diphtheroids (corynebacterium species), anaerobic diphtheroids (propriono-bacterium acnes), and coagulase-negative staphylococci. gram-negative bacilli may be present in limited numbers in intertriginous areas. localized cutaneous infections occur in ostensibly normal hosts, often after trivial trauma, examples bei ...19846372467
mycobacterium marinum infection of the skin in japan. 19846376574
experimental mycobacterial infections of cba/n mice.in an effort to assess the contribution of b-lymphocyte-mediated mechanisms to the immune responses to several mycobacteria, responses to these intracellular pathogens were compared in immunologically normal cba/cahn mice and in histocompatible cba/n (xid) mice, which exhibit abnormalities of b-lymphocyte function. swelling in response to local inoculation with mycobacterium marinum was significantly greater in the hind feet of cba/cahn mice than in those of cba/n mice, but the difference was ve ...19846381393
specificity and distribution of alpha antigens of mycobacterium kansasii and mycobacterium marinum.specificity of antigenic determinants in alpha antigens of mycobacterium kansasii and mycobacterium marinum was investigated in 170 strains classified into 16 species of slowly growing mycobacteria by the agar gel diffusion technique using the respective absorbed anti-alpha serum. the specific antigenic determinants in alpha antigen of m. kansasii were detected in all of the 20 strains classified as m. kansasii, and not in strains belonging to other species. the specific antigenic determinants i ...19846207754
fish fancier's finger.infection of the flexor tendon sheath and proximal interphalangeal joint by mycobacterium marinum is described. the characteristic features of this unusual infection are delineated.19846737381
benzylamines: synthesis and evaluation of antimycobacterial properties.the synthesis of benzylamines with various n-alkyl chains and substituents in the aromatic system as well as their evaluation on mycobacterium tuberculosis h 37 ra are described. the most active compounds in this test, n-methyl-3-chlorobenzylamine (19, mic 10.2 micrograms/ml), n-methyl-3,5-dichlorobenzylamine (93, mic 10.2 micrograms/ml), and n-butyl-3,5-difluorobenzylamine (103, mic 6.4 micrograms/ml), also exhibited a marked inhibitory effect on mycobacterium marinum and mycobacterium lufu use ...19846433022
[swimming pool granuloma--an atypical mycobacterial infection].after an introduction on the problem of swimming pool or fish tank granulomas--chronic granulomatous skin infections with mycobacterium marinum--we present two of our own cases. the disease is discussed and the signs and symptoms, histological changes, and therapeutic methodology presented.19846469642
response of the popliteal lymph node to reinfection of the hind foot pad of the mouse with mycobacterium marinum.in c57bl mice inoculated with mycobacterium marinum in the right hind foot pad 2 weeks earlier ("previously infected mice"), inoculation of m. marinum into the left hind foot pad was followed by accelerated enlargement of the left popliteal node. popliteal-node lymphocytes harvested from previously infected donors, labeled with 3h-uridine in vitro, and infused intravenously into previously infected recipients at the time of reinfection in the left hind foot pad homed on the left popliteal node. ...19846481791
sporotrichoid mycobacterium marinum infection. report of a ten-year case. 19846500798
mycolic acid patterns of some species of mycobacterium.representative strains of some species of mycobacterium were degraded by both acid and alkaline methanolysis. two-dimensional thin-layer chromatography was used to determine the patterns of mycolic acids and other long-chain components in these methanolysates. patterns composed of alpha-, methoxy- and ketomycolates were found in mycobacterium asiaticum, mycobacterium bovis, mycobacterium gastri, mycobacterium gordonae, mycobacterium kansasii, mycobacterium marinum and mycobacterium tuberculosis; ...19846517656
[tenosynovitis of the hand due to mycobacterium marinum. apropos of a case].the authors report one case of mycobacterium marinum of the deep structures of the hand and review the literature on the subject. the symptoms are not specific: biopsy and culture are essential for diagnosis. as chemotherapy does not seem to be of help, wide surgical incision is the appropriate treatment.19854026432
the histopathology of mycobacterium marinum synovitis.eight patients with culture-proven mycobacterium marinum synovitis had synovial specimens with a remarkably similar histologic appearance. there was considerable synovial hyperplasia, and the synovium was thickened by a moderately intense lymphohistiocytic infiltrate, notably devoid of plasma cells. fibrin covered some synovial surfaces. giant cells were both of the langerhans' and foreign body types. granulomas were noncaseating but varied in frequency and degree of definition. knowledge of thi ...19853984939
the histopathologic spectrum in mycobacterium marinum infection.review of nine culture-positive cases of mycobacterium marinum infection revealed a broad range in the histopathologic features of lesions produced by this organism. four synovial lesions and five cutaneous infections were observed. a range of inflammatory changes were seen in both synovial and skin lesions, varying from mostly acute inflammation with suppuration to a more chronic process with numerous, well-formed granulomas. organisms were observed in the biopsy sections of only one of the nin ...19853840985
mycobacterium marinum infections in man. 19853886781
the free lipids of mycobacterium leprae harvested from experimentally infected nine-banded armadillos.the free lipids of a sample of mycobacterium leprae were extracted by a procedure designed to produce separate non-polar and polar fractions. the composition of these lipids was analysed semi-quantitatively by five special thin-layer chromatographic systems covering the total range of mycobacterial lipid polarities. in order of increasing polarity, the major lipids were dimycocerosates of phthiocerol a, phthiocerol b and phthiodiolone a, glycosyl phenolphthiocerol dimycocerosates and phospholipi ...19853903039
[swimming pool granuloma--a mycobacteriosis].we report on a patient suffering from swimming pool granuloma after having handled in fresh-water aquarium. as the causative organism, we could isolate mycobacterium marinum from a nodular, ulcerous lesion.19853984425
mycobacterium marinum infection in a 4-year-old child.infections with mycobacterium marinum are uncommon in children but should be considered by a physician confronted with chronic, poorly healing skin lesions. a case of such an infection in a 4-year-old child is presented. presenting signs and symptoms, differential diagnosis, and treatment of these infections are discussed.19853987170
multiplication of mycobacterium marinum within phagolysosomes of murine macrophages.both in vivo and in vitro, mycobacterium marinum organisms were found to multiply within phagolysosomes of murine macrophages. it thus appears that m. marinum are neither killed nor inhibited from multiplying by lysosomal enzymes.19853997252
importance of the footpad lesion in the mouse response to local inoculation of mycobacterium marinum.the importance of the footpad lesion was studied in cba mice inoculated in the hind footpad with viable or heat-killed mycobacterium marinum popliteal or popliteal and inguinal lymphadenectomy was followed by modest enhancement of the process only when node excision was carried out 6 days after inoculation of a small number of viable organisms. following inoculation in the footpad of a large number of heat-killed organisms, only 10% of the inoculum was recovered from the site of inoculation, onl ...19854004150
unusual cutaneous dissemination of a tropical fish tank granuloma.a patient with an unusual disseminated tropical fish tank granuloma is presented. the infection manifested first as red, subcutaneous nodules of the right hand and forearm. during subsequent days and weeks, nodules appeared on the left arm, on the ventral and dorsal thorax, on one leg, and the face. the diagnosis was based on, in addition to the history and the clinical aspects, a positive reaction to intracutaneous testing with a specific mycobacterium marinum antigen and on the histologic exam ...19854064761
systemic mycobacterium marinum infection in an amazon manatee. 19854077647
resistance to mycobacteria in mice treated with fractionated total lymphoid irradiation (tli) and in mice reconstituted with allogenic bone marrow cells following radiotherapy.the increased clinical use of total lymphoid irradiation (tli) as an immunosuppressive adjunct in transplantation suggested the need for determining the effects of tli on the in vivo susceptibility of animals to infections controlled by cell-mediated immunity. tli-treated, tli-treated and splenectomized, and chimeric mice prepared with tli were inoculated in the hind foot pad with mycobacterium marinum or mycobacterium leprae. although m. marinum organisms multiplied in greater numbers in the tl ...19853155713
amikacin treatment for mycobacterium marinum infection. 19863546444
immunogenic behaviour of mycobacterium marinum (sato) in mice. 19863557568
aquarium-borne mycobacterium marinum skin infection. report of a case and review of the literature.a 33-year-old fish fancier developed a protracted skin infection that ultimately was found to be caused by mycobacterium marinum. the organism was isolated from the lesion as well as from infected fish taken from his home aquarium. the lesion resolved after a six-week course of oral sulfamethoxazole and trimethoprim. forty-four additional cases of culture-proved m marinum skin infections acquired from aquariums and reported in the english-language literature are reviewed. almost universally, the ...19863487289
an unusually aggressive mycobacterium marinum hand infection.an unusually aggressive mycobacterium marinum infection of the hand that progressed despite surgical and medical treatment is presented. the infection progressed over a 3-week period after the patient had surgical treatment and received isoniazid (inh), rifampin, and ethambutol hydrochloride. the patient had a collar-button abscess, destruction of the metacarpophalangeal (mcp) joint capsule, flexor and extensor tenosynovitis, and metacarpal and proximal phalanx bone destruction at the mcp joint ...19863760509
therapy of mycobacterium marinum infections. use of tetracyclines vs rifampin.we describe four patients with mycobacterium marinum infections who did not respond to two- to six-week courses of therapy with tetracycline, minocycline, and doxycycline. all four patients had prompt responses to therapy with either rifampin alone (two patients) or rifampin in combination with ethambutol. results of antimicrobial sensitivity tests may be helpful in guiding therapy. rifampin may be the drug of choice for treatment of these infections.19863963983
purification and characterization of atp:amp phosphotransferase from mycobacterium marinum.atp:amp phosphotransferase (ec 2.7.4.3) (adenylate kinase) has been purified 1746-fold from mycobacterium marinum (atcc 927) by successive column chromatography on deae-cellulose (de-53), reactive blue agarose, sephadex g-75, hydroxyapatite and, finally, deae-sephadex a-50. the final enzyme preparation had a specific activity of 576 mumol/min per mg protein with an overall yield of 51%. the preparation was homogeneous by sodium dodecyl sulfate polyacrylamide gel electrophoresis. the enzyme was e ...19863004585
mycobacterium marinum infection in gnotobiotic nu/nu mice pretreated with cyclophosphamide and silica.germfree nude mice (nmrj-nu/nu) and germfree nu/+ mice were infected with mycobacterium marinum in the footpad test. after pretreatment with 400 mg/kg cyclophosphamide, significantly higher amounts of m. marinum were reached in the footpad and in the liver. on the other hand, the yield of m. marinum could not be elevated by in vivo inhibition of macrophages with silica.19863020845
bactericidal activity of alkaline glutaraldehyde solution against a number of atypical mycobacterial species.the mycobactericidal activity of 2% alkaline glutaraldehyde solution was determined using standardized suspensions of 10 species of atypical mycobacteria and compared with that for virulent mycobacterium tuberculosis. suspensions of m. avium, m. intracellulare and m. gordonae were more resistant to disinfection by the glutaraldehyde than were virulent tubercle bacilli while m. kansasii, m. scrofulaceum and m. szulgae were somewhat more susceptible. mycobacterium marinum, m. smegmatis and m. fort ...19863096931
selective enzyme staining procedures for characterization of mycobacterial immunoprecipitates.selective staining procedures for four different enzymes (malate dehydrogenase, glutamic oxaloacetic transaminase, leucine aminopeptidase and glucose phosphate isomerase) in combination with two-dimensional immunoelectrophoresis were successfully applied to the analysis of antigen preparations from mycobacteria. thus, a precipitate corresponding to malate dehydrogenase could e.g. be demonstrated in multi-linear precipitation patterns of mycobacterium avium, mycobacterium bovis bcg, mycobacterium ...19862417958
mycobacterium marinum infection in a mechanic. 19872957157
tetracyclines in therapy of mycobacterium marinum infections. 19873675110
failure of doxycycline treatment in aquarium-associated mycobacterium marinum infections.two cases of aquarium-associated mycobacterium marinum infections are described. neither was cured by the initial therapy consisting of surgical excision followed by doxycycline treatment. both strains of m. marinum were shown to be resistant to doxycycline. in one patient the lesions were subsequently healed with cotrimoxazole. the other patient, a 12-year-old girl with sporotrichoid spread of the lesions on the lower arm, failed to respond satisfactorily to a combination of rifampicin and etha ...19873423745
antigen-specific t-cell anergy in progressive mycobacterium marinum infection in humans.the cellular immune responses of 12 patients with culture-proved mycobacterium marinum infection involving deep tissues were studied. of the 12 patients, 11 failed to respond to m. marinum antigens. all of the patients had, however, normal blastogenic responses to concanavalin a, phytohemagglutinin, pokeweed mitogen, and the antigens tetanus toxoid and candida albicans. in contrast, 9 of 14 healthy fishermen responded to the m. marinum antigens with significant in-vitro blastogenesis. infection ...19873499107
fish-tank granuloma. the first reported case in south africa.the first case of infection with the non-tuberculous mycobacterium, mycobacterium marinum, in south africa is reported. of special interest was the linear nodular (sporotrichoid) appearance.19873563758
mycobacterium marinum infections. a problem of recognition, not therapy? 19873579434
mycobacterium marinum infections of the hand.fifteen patients had culture proven mycobacterium marinum infections of the hand; 11 had injured their hands while fishing in water around long island. no patient had type i lesions (verrucal), six patients had type ii lesions (subcutaneous granulomas), and nine patients had type iii lesions (deep). histologic examination showed noncaseating granulomas in all cases. a specific defect in the patients' lymphocytes ability to respond to m. marinum antigens was identified. a combination of surgery a ...19873584892
mycobacteriosis in cultured striped bass from california.striped bass (morone saxatilis) juveniles raised in an intensive culture system had chronic mortality resulting from infections with mycobacterium marinum. approximately one-half of a population of 900 yearlings succumbed to the disease and 80% of those remaining were infected. the bacteria were isolated on petrignani's medium after 7 days at 25 c and subcultures grew at temperatures from 20 to 37 c. the disease was characterized by systemic nodular lesions in all major organs. older tubercles c ...19873625895
mycobacterium marinum infection of the hand and wrist. results of conservative treatment in twenty-four cases.inadequate débridement, extensive scarring, and breakdown of the wound have been commonly encountered after surgical débridement has been employed as the initial treatment of infection with mycobacterium marinum involving the deep structures of the hand. because of our disappointment with the results of this form of treatment, from 1982 to 1986 we treated twenty-four patients who had such an infection with rifampicin and ethambutol after a diagnostic biopsy was done. surgical treatment was defer ...19873667646
a case of clinically unsuspected mycobacterium marinum infection. 19873689470
cutaneous mycobacterium marinum infection ("swimming pool granuloma"). 19873311342
analysis of dimycocerosates of glycosylphenolphthiocerols in the identification of some clinically significant mycobacteria.extracts of representative mycobacteria were examined by thin-layer chromatography for glycosylphenolphthiocerol dimycocerosates. the glycolipid typical of mycobacterium bovis was also found in mycobacterium africanum and mycobacterium microti, but it was absent in mycobacterium bovis an 5. mycobacterium gastri strains contained a glycolipid which was chromatographically similar to that in mycobacterium kansasii. representatives of mycobacterium marinum produced a distinct glycolipid type, and o ...19873326746
mycobacterium-induced infectious granuloma in xenopus: histopathology and transmissibility.the acid-fast bacteria present in the transmissible putative xenopus lymphosarcoma (px1) (m. balls, cancer res., 22: 1142-1154, 1962) were isolated and identified as mycobacterium marinum. m. marinum induces an infectious granuloma in xenopus which is histopathologically indistinguishable from xenopus "lymphosarcoma" (px1). it had been reported that the filtrate (0.22-micron pore size) and the supernate of ultracentrifugation (20,000 x g) of the pxl tissue homogenate were bacteria free and could ...19883338088
mycobacterium chelonei tenosynovitis.most atypical mycobacterium infections of the hand are caused by mycobacterium marinum. we are presenting a rare case of a mycobacterium chelonei tenosynovitis. the correct diagnosis is important because the chelonei species is resistant to most antituberculosis drugs. treatment should include surgical debridement and long-term chemotherapy after sensitivities have been determined.19883364921
swimming pool granulomas due to mycobacterium marinum: an occupational hazard of lifeguards.m. marinum appears to be an occupational hazard to lifeguards who clean swimming pools. if such persons have any persisting "boil," "ulcer," or "granuloma," these lesions should be considered to be caused by m. marinum, unless proven otherwise.19883391044
cutaneous infection with mycobacterium avium-intracellulare scrofulaceum intermediate: a new pathogenic entity.the atypical or environmental mycobacterial organisms constitute a large group of potential agents in the pathogenesis of cutaneous infection. the most commonly encountered mycobacterial infection after contact with water is mycobacterium marinum. we report an unusual case of cutaneous mycobacterial infection caused by a newly described opportunistic mycobacteria, m. avium-intracellulare scrofulaceum intermediate. this case emphasizes the difficulty in distinguishing among the species m. avium-i ...19883170812
septic arthritis of the hand due to mycobacterium marinum.mycobacterium marinum infections of the hand are very rare in the united kingdom and we found only one case of involvement of deep structures (tenosynovitis) in the british literature. we report a case of septic arthritis due to the organism.19883171307
utilisation of ethanol as sole carbon source by mycobacterium marinum. 19883188235
mycobacterium marinum infection in a patient with cryptosporidiosis and the acquired immunodeficiency syndrome.we report a case of aquarium-borne mycobacterium marinum infection in a patient who presented simultaneously with cryptosporidiosis and the acquired immunodeficiency syndrome.19883203532
synovial involvement by mycobacterium marinum. a histopathological study of 25 culture-proven cases.the present culture-proven cases are contrary to the generally held view that infection with mycobacterium marinum is habitually a superficial infection without potentially serious consequence. a wide spectrum of pathological lesions may be seen in the synovium and adjacent tissues in patients infected by m. marinum. variations in the morphology of the inflammatory reaction occurs both between cases and, to a lesser extent, in different areas of individual cases. the inflammation ranges from the ...19883241735
mycobacterium marinum infections of the hand and wrist. results of conservative treatment in twenty-four cases. 19883356732
[mycobacterium marinum infections in humans. 2. infections caused by m. marinum]. 19883054220
[review: mycobacterium marinum infections in humans. 1. bacteriology of mycobacterium marinum]. 19883074215
isolation and characterization of recombinant lambda gt11 bacteriophages expressing eight different mycobacterial antigens of potential immunological relevance.a genomic lambda gt11 dna library of mycobacterium tuberculosis was screened for expression of mycobacterial protein antigens with murine monoclonal antibodies. the reactivity patterns of the monoclonal antibodies ranged from those showing a limited interspecies reactivity to antibodies widely cross-reactive among different mycobacterial species. twelve recombinant bacteriophages were isolated, containing eight mycobacterial genes (paa, pab, pac, pad, paea, paeb, pafa, and pafb) encoding protein ...19882451643
comparative studies of antigenic glycolipids of mycobacteria related to the leprosy bacillus.the leprosy bacillus, mycobacterium leprae, is a member of a small group of mycobacteria comprising the species mycobacterium bovis, mycobacterium marinum, mycobacterium kansasii, mycobacterium tuberculosis, mycobacterium ulcerans and related taxa. this relationship is based on the similarity of the characteristic lipid types in the cell envelope. mycobacterium leprae produces a phenolic glycolipid antigen which is species specific. this communication reports a comparison of the specificity of t ...19892504005
specificity and antigenicity of mycoside g and other glycolipids from mycobacterium marinum.the purpose of this work was to examine the immunologic properties of the phenolicglycolipid produced by m. marinum (mycoside g). cell mass processed with organic solvents yielded a lipid extract containing mycoside g and four other glycolipid fractions (g2 to g5). no mycoside g was found in the mycobacterium marinum type strain. neither mycoside g, nor fractions g2, g3 and g4 were immunogenic in the rabbit whereas fraction g5 was very immunogenic. the immune serum raised in the rabbit showed th ...19892504015
[fish breeder granuloma: infection caused by mycobacterium marinum and other atypical mycobacteria in the human. analysis of 8 cases and review of the literature].granulomatous lesions of the skin and tendon sheaths after exposure to fish tank or aquarium water are frequently caused by non-tuberculous so-called atypical mycobacteria. mycobacterium marinum is the species most often isolated from such lesions. rarely, other non-tuberculous species of mycobacteria may be isolated. in contrast to swimming-pool granuloma as the epidemic form of mycobacterium marinum infection of man, fish tank granuloma seems to be a rare sporadic human disease that is often m ...19892533660
case study: mariner's tb.mycobacterium marinum causes tuberculosis in fish and shellfish and cutaneous lesions in humans. it is transmitted from fish to humans by inoculation. the case presented involved a nodule on the wrist and was misdiagnosed as arthritis; the nodule was excised. symptoms of tuberculosis persisted over a 2-year period. this case study can be generalized to a population of workers in the seafood industry, water hobbyists, and fish and shellfish enthusiasts. education and research is needed to inform ...19892757709
[in vitro determination of the sensitivity of mycobacteria to fluoroquinolones].in vitro activity of four fluorinated quinolones: pefloxacin, norfloxacin, ciprofloxacin, ofloxacin were determined against various clinical isolates of mycobacteria. the method of agar dilution was used, seventy strains of ten species were tested: mycobacterium tuberculosis (25), mycobacterium bovis (5), mycobacterium africanum (2), bcg (5), mycobacterium kansasii (6), mycobacterium marinum (5), mycobacterium avium (11), mycobacterium xenopi (6), mycobacterium chelonae (3), mycobacterium fortui ...19892780092
[mycobacterium marinum infection of the hand after a visit to the tropics]. 19892796492
mycobacterium marinum flexor tenosynovitis.four culture-positive cases of flexor tenosynovitis of the hand caused by mycobacterium marinum are reported. the organisms were cultured at 32 degrees. all patients were treated with a combination of flexor tenosynovectomy and antimycobacterial treatment with ethambutol and rifampin. the length of antimycobacterial treatment ranged from nine to 22 months. all four patients responded to treatment with cessation of signs of infection, increased range of motion, and complete wound healing.19892910612
sclerokeratitis caused by mycobacterium marinum. 19892817067
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