Publications

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current concepts in therapy: the treatment of acne with antibiotics. 19734267707
[corynebacterium acnes. a definite factor in the complex etiology of acne vulgaris?]. 19734268285
acne vulgaris. 19734271327
[significance of triglyceride splitting by c. acnes in acne vulgaris (author's transl)]. 19734271341
benefit and mischief from commensal bacteria. 19734271885
the role of anaerobic coryneforms on specific and non-specific immunological reactions. i. effect on particle clearance and humoral and cell-mediated immunological responses. 19734717941
lympho-reticular stimulatory properties of corynebacterium parvum and related bacteria. 19734726332
microcolony size of microbes on human skin. 19734726334
preliminary results of nonspecific immunotherapy for lung cancer. 19734729331
fermentative and serological studies on propionibacterium acnes.seventy-two propionibacterium acnes strains, among which were five from the american type culture collection, five from the center for disease control, and four of group ii of voss, were thoroughly examined both biochemically and serologically. on the basis of the fermentation of inositol, maltose, mannitol, and sorbitol, eight biotypes were distinguished. by means of tube agglutination tests with the five absorbed antisera, 95, c51, d34, s140, and beck, 11 serotypes were defined. the biotypes a ...19734632849
effect of bcg and corynebacterium parvum on allograft survival after rabbit antimouse lymphocyte serum and donor bone marrow. 19734618660
[study of anaerobic corynebacteria isolated from 9 000 hemocultures]. 19744619759
cancer immunotherapy: an overview. 19744620437
corynebacterium parvum as an immunotherapeutic anticancer agent. 19744620441
lasting rejection of mammary adenocarcinoma cell tumors in dba-2 mice with intratumor injection of killed corynebacterium parvum. 19744810906
the effect of transplanted methylcholanthrene induced fibrosarcomata and corynebacterium parvum on the immune response of cba and a-hej mice to thymus dependent and independent antigens. 19744820942
corynebacterium parvum: a synonym for propionibacterium acnes? 19744826546
anti-tumour effect in vitro of lymphocytes and macrophages from mice treated with corynebacterium parvum. 19744830143
proceedings: immunotherapy of moloney sarcoma virus tumours in mice with corynebacterium parvum. 19744832648
increased phagocytic cell activity and anaemia in corynebacterium parvum treated mice. 19744835797
[stimulating effect on in vitro cell growth of spleen cells from tumor bearing mice]. 19744849772
chronic meningitis caused by propionibacterium acnes. a potentially important clinical entity. 19744858158
tumour growth, phagocytic activity and antibody response in corynebacterium parvum-treated mice. 19744549691
an overview of acne. 19744274207
acne: perspectives. 19744274209
the microflora of the face and acne lesions. 19744274210
genesis of free fatty acids. 19744274211
acne vulgaris and free fatty acids. a review and criticism. 19744275329
the glycerol ester hydrolase (ec 3.1.1.3) from corynebacterium acnes: a serine lipase. 19744275466
characteristics of the extracellular lipases from corynebacterium acnes and staphylococcus epidermidis. 19744276477
[antibiotic sensitivity of corynebacterium acnes]. 19744276912
[current data on acne juvenilis with reference to the role of corynebacterium acnes]. 19744277158
acne. pathogenesis and treatment. 19744278415
corynebacterium acnes and other anaerobic diphtheroids from human skin. 19744278837
carriage of corynebacterium acnes in school children in relation to age and race. 19744279690
[an immunobiological treatment for acne vulgaris (author's transl)]. 19744280517
depression of delayed-type hypersensitivity by corynebacterium parvum: mandatory role of the spleen. 19744281350
studies on the mechanism of action to topical benzoyl peroxide and vitamin a acid in acne vulgaris. 19744283462
the skin microflora in acne vulgaris. 19744271839
immunotherapy of cancer: regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets. 19744364736
non-specific immunostimulation in bronchogenic cancer. 19744370224
the effect of bacterial adjuvants on allograft survival after anti-lymphocyte serum (als) and donor bone marrow in mice. 19744373388
the normal microbial flora of the skin. 19744373839
the mechanism of inhibition by corynebacterium parvum of the growth of lung nodules from intravenously injected tumour cells. 19744376512
[the antiviral properties of corynebacterium parvum]. 19744376977
the effect of a single and repeated administration of corynebacterium parvum on bone marrow macrophage colony production in syngeneic tumor-bearing mice. 19744419513
properties of corynebacterium acnes bacteriophage and description of an interference phenomenon.nine virulent bacteriophages of the anaerobe corynebacterium (propionibacterium) acnes, the p-a series, are dna phages, with long, curved nonretractile tails (130 nm) without tail plates or fibers. they have isometric heads (420 by 460 nm), and are placed in bradley's group b-1. there is permanent plaque suppression at highest phage concentrations. after 100- to 1,000-fold dilution, plaques are evident. the latent period is 1 h and burst size 25. cross-neutralization data of antisera for the nin ...19744431080
antitumour effects of corynebacterium parvum in mice. 19744435007
studies on the organ uptake of 51cr-labeled sheep erythrocytes in the evaluation of stimulation of res phagocytic function in the mouse. 19744455902
the effect of a single and repeated administration of corynebacterium parvum on bone marrow macrophage colony production in normal mice. 19744455907
immunoprophylaxis and immunotherapy for a murine fibrosarcoma with c. granulosum and c. parvum. 19744459276
rejection of tumors and metastases in fischer 344 rats following intratumor administration of killed corynebacterium parvum. 19744459281
studies of the corynebacterium parvum-associated anaemia in mice. 19744466596
perspectives in immunotherapy of lung cancer. 19744471091
tumor immunotherapy: current trials and future developments. 19744471228
effect of corynebacterium parvum on cytotoxicity of regional and nonregional lymph node cells from animals with tumors present or removed. 19744471644
[investigations of the serological relationship between actinomyces israelii and corynebacterium acnes (author's transl)]. 19744151213
enhancement and depression of the antibody response in mice caused by corynebacterium parvum. 19744157122
[considerations on some cases of acute lymphatic leukemia treated with aspecific active immunotheraphy]. 19744526571
the effect of preadministration of corynebacterium parvum on the protection afforded by heat-killed and acetone-killed vaccines against experimental mouse typhoid.mice given an intraperitoneal injection of 0.5 mg. corynebacterium parvum (dry weight) before vaccination with heat-killed (hk) or acetone-killed (ak) salmonella typhimurium vaccine and later challenged intraperitoneally with s. typhimurium strain 1566, showed a statistically significant increase in mortality when compared with mice that had received only c. parvum but no vaccine. they also showed a higher mortality rate than mice receiving only hk or ak vaccine or mice that had received no vacc ...19744593737
present aspects of the immunology of cancer. 19744604939
studies on the cecal microflora of commercial broiler chickens.a study was made of the cecal microflora isolated from broilers (5-week-old) reared under typical commercial husbandry conditions. three hundred and twenty-five bacterial strains (randomly isolated from colonies representing 49 to 81% of the microscopic count) were isolated from cecal digesta of six animals on a rumen fluid roll tube medium (m98-5). seventy-seven percent of these strains consisted of strict anaerobes: gram-negative, pleomorphic cocci (5.2%), peptostreptococcus (1.5%), gram-posit ...19744608322
immunotherapy of guinea pig cancer with bcg. 19744608693
antibiotic usage in dermatological practice. 19744609931
the effect of corynebacterium parvum on the structure and function of the lymphoid system in mice. 19744611769
current status of immunotherapy. 19744616826
immunostimulation with bacterial phospholipid extracts.injection of bacterial phospholipid extracts (ebp) into mice increased their resistance towards a listeria monocytogenes infection. the blood clearance of virulent salmonella typhimurium was enhanced and the degree of clearance correlated with the dose of extract injected. the multiplication of listeria monocytogenes in spleen and liver of mice was inhibited and this inhibition was also correlated with the amount of extract injected. the absence of apparent toxicity in mice, of splenoand hepatom ...19744205595
potential antileprotic agents. 3. inhibition of mycobacterial dihydrofolic reductase by 2,4-diamino-5-methyl-6-alkylquinazolines. 19744209923
corynebacterium parvum as a therapeutic antitumor agent in mice. i. systemic effects from intravenous injection. 19744213015
corynebacterium parvum as a therapeutic antitumor agent in mice. ii. local injection. 19744213016
a technique for sampling micro-organisms from the pilo-sebaceous ducts. 19744213708
hydrosoluble immunopotentiating substances extraced from corynebacterium parvum. 19744217774
properties of an antigenic polysaccharide from corynebacterium parvum.corynebacterium parvum strain 10390 is an antitumor agent and stimulant of the reticuloendothelial system and produces a soluble antigen towards the end of its growth cycle. this material, which is a cell wall component and can also be released from the organism by acid or alkaline hydrolysis, has been purified. it is an acidic polysaccharide of molecular weight 100,000 to 150,000 and contains galactose, glucose, fucose, n-acetylgalactosamine, n-acetylglucosamine, uronic acids, sialic acids, and ...19744138438
effects of corynebacterium parvum and freund's adjuvants on amphibian antibody responses. 19744142047
letter: methyl-cholanthrene-induced sarcomata in mice after immunisation with corynebacterium parvum plus syngeneic subcellular membrane fractions. 19744143365
letter: corynebacterium parvum and anaesthetics. 197546085
editorial: immunological control of cancer. 197546965
letter: anaerobic corynebacteria and anaesthetics. 197547129
letter: corynebacterium parvum and anaesthetics. 197547551
letter: adjuvant contact suppression of experimental tumours. 197548032
letter: immunological control of cancer. 197548154
letter: toxicity of intravenous corynebacterium parvum. 197553574
letter: side-effects of intravenous corynebacterium parvum. 197553755
evidence for an allotypic marker on canine immunoglobulin. 197553927
[inhibition of antigenic competition by immunostimulants].the diminution of immune response against srbc induced in mice, by a prior injection of hrbc was counteracted by addition of certain immunostimulants to srbc. the intensity of inhibition of antigenic competition was related to the quantity of immunostimulant added to srbc. some immunostimulants (b. abortus, lipopolysaccharide) were more active than others (c. parvum, poly i : c). to inhibit antigenic competition immunostimulant had to be injected after or in mixture with srbc never before.197556240
analysis of anaerobic coryneform cell wall antigens by radioimmunoassay. 197556300
the effect of corynebacterium parvum therapy on immunoglobulin class and igg subclass levels in cancer patients.detailed serological studies have been undertaken in a small group of cancer patients receiving nonspecific immunotherapy with corynebacterium parvum (c. parvum). these patients included 4 cases of recurrent malignant melanoma, 2 of stomach cancer and 2 of recurrent breast cancer. they all received an initial i.v. infusion of 20 mg of a formol killed suspension of c. parvum followed by 2 mg (i.m.) at weekly intervals for 10-11 weeks. this protocol consistently resulted in an increase in the circ ...197561040
[effect of a polysan preparation for the treatment of acne on the growth of corynebacterium acnes and staphylococcus pyogenes aureus]. 1975125629
quantification of bacteria in isolated pilosebaceous follicles in normal skin.a technique for quantitating bacteria in isolated pilosebaceous follicles is described. this involves microdissection of the follicles from biopsies of skin, using the method of chemical pretreatment of skin to facilitate the separation of the epidermis and epidermal appendages from the dermis. the aerobic cocci and anaerobic diphtheroids in pilosebaceous follicles in 66 biopsies of scalp and 48 biopsies of skin of the upper back were quantitated using this technique. on the back, aerobic staphy ...1975127814
ad hoc committee report: systemic antibiotics for treatment of acne vulgaris: efficacy and safety. 1975128326
scientific approach to the treatment of acne vulgaris. 1975129306
lipolytic activity of microorganisms in acne vulgaris. 1975129776
ultrastructure of human sebaceous follicles and comedones following treatment with vitamin a acid.ultrastructural findings in normal human sebaceous follicles, of comedones from acne patients, and from comedones during topical treatment with vitamin a acid (vaa) are described. in normal human sebaceous follicles, the two segments of the infundibulum-the acroinfundibulum and the infrainfundibulum-show differing ultramorphological patterns of keratinization. the incomplete horny layer of the infrainfundibulum is physiological and seems to be necessary for its normal function. on the other hand ...1975130781
[first clinical trials of treatment of primary liver cancer with immunostimulating agents administered by systemic or intratumoral route]. 1975170046
histological and combined chemoimmunostimulation therapy studies against a murine leukemia.a graffi murine leukemia was utilized as a model system to investigate the effect of chemoimmunostimulation therapy. subcutaneous inoculation of approximately 1.0 times 10(6) tumor cells resulted in a rapidly growing tumor at the site of inoculation and subsequent development of splenomegaly and lymphoadenopathy. all animals succumbed to the leukemia within 24 to 30 days. treatment of diseased animals with two courses of cytoxan over a 2-week period resulted in a remission period of approximatel ...1975170212
suppression of cell-mediated tumour immunity by corynebacterium parvum. 1975170531
effect of pretreatment with mycobacterium bovis (strain bcg) and immune syphilitic serum on rabbit resistance to treponema pallidum.stimulation of the rabbit reticuloendothelial system with viable mycobacterium bovis (strain bcg), and other agents, had no effect on the development of syphilitic lesions after intradermal or intravenous inoculation with graded doses of treponema pallidum (virulent nichol's strain; mean infective doses less than 10). the simultaneous administration of immune syphilitic rabbit serum retarded the development of lesions, but this appeared to be due solely to the immune serum, suggesting no synergi ...1975172450
effect of corynebacterium acnes on interferon production in mouse peritoneal exudate cells.corynebacterium acnes, an organism closely related to c. parvum, has been recognized to have a striking effect on the reticuloendothelial system, as well as on both humoral and cellular immunity. in mice previously exposed to c. acnes, serum interferon levels induced by injection of newcastle disease virus (ndv), chikungunya virus (cv), and polyinosinic-polycytidylic acid are suppressed. when peritoneal macrophages and lymphocytes from animals exposed to c. acnes were cultivated in vitro, their ...1975234914
[oral antigen treatment (oral vaccination) in acne diseases]. 1975236624
quantitative microbiology of the scalp in non-dandruff, dandruff, and seborrheic dermatitis.the composition of the scalp microflora was assessed quantitatively in normal individuals and in patients with dandruff and seborrheic dermatitis, disorders characterized by increasing scaling. three organisms were constantly found: (1) pityrosporum, (2) aerobic cocci, and (3) corynebacterium acnes. pityrosporum (mainly pityrosporum ovale) made up 46% of the total microflora in normals, 74% in dandruff, and 83% in seborvheic dermatitis. the geometric mean number of organisms per cm-2 in non-dand ...1975237965
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