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characterization of the structure and properties of the his 62-->ala and arg 38-->ala mutants of yeast phosphoglycerate kinase: an investigation of the catalytic and activatory sites by site-directed mutagenesis and nmr.the role of two "basic patch" residues, arg-38 and his-62, in the catalytic function and anion-dependent activation of yeast 3-phosphoglycerate kinase (pgk) was investigated by site-directed mutagenesis. steady-state kinetics and nmr experiments were conducted to characterize the functional properties and structural integrity of the r38a and h62a mutants. the results of these studies, in combination with earlier mutagenesis experiments, suggest that arg-38 is the only catalytically essential res ...19921304916
high-level expression using baculovirus, purification, and characterization of a monomeric form of type ii calmodulin-dependent protein kinase.the type ii calmodulin-dependent protein kinase is an oligomer existing in multiple isozymic forms. to facilitate investigations of the regulatory mechanisms of this complex enzyme, we have constructed a truncated, calmodulin-dependent monomer of the alpha subunit. the n-terminal enzyme fragment (alpha 315) was expressed at high levels in a baculovirus/insect cell expression system. the recombinant protein was purified chromatographically using deae-cellulose, calmodulin-sepharose, and affigel b ...19921330134
isolation and sequence of a cdna encoding the precursor of a bombesinlike peptide from brain and early embryos of xenopus laevis.a cdna encoding the precursor of a bombesinlike peptide was isolated from brain of xenopus laevis. the predicted end product resembles neuromedin b, which was originally isolated from mammalian spinal cord. the mrna for this precursor was also present in gastrointestinal tract and in ovaries. moreover, it could be detected in early embryos (stage 2 and stage 10) of x. laevis. these findings suggest novel roles for peptides of the bombesin family in oocyte maturation and early amphibian developme ...19921409705
determination of concentrations by time domain fitting of proton nmr echo signals using prior knowledge.a fast and flexible time domain iterative fitting procedure that can be used to fit free induction decays as well as echo-like signals is described. damping constants of the first and second part of the echo do not have to be identical. prior knowledge can be used to diminish the number of parameters to be fitted, which results in an improved accuracy. it is shown how prior knowledge is mathematically incorporated in the gauss-newton method. from proton nmr measurements of model solutions actual ...19921435212
editorial: lead in petrol. 199248178
filling defect in the urinary bladder. 199345865
[epidemiological studies of chronic bronchitis in the auxiliary personnel of the a. cadarelli hospital. preliminary results]. 19961225230
[treatment of jaw fractures using a compression plate]. 199723455
kinetic study of the hydrolysis of pancuronium bromide. iii. media effects. 199720732
quality of life consequences of chemotherapy-induced emesis.nausea and vomiting following chemotherapy administration are common and often overlooked causes of impairment in cancer patients. the goal of this study was to explore the broad range of consequences associated with this specific acute toxicity of chemotherapy. specific objectives were: (1) create and test scales specifically designed to assess the impact of chemotherapy-induced nausea and vomiting or patients' daily function; (2) examine changes in quality of life of cancer patients 3 days fol ...19981299465
volunteers can help patients adjust. 1998107087
the pathology of tumors. part 1: precancerous and pseudomalignant lesions. 1998106933
separation of glycoprotein-derived oligosaccharides by thin-layer chromatography. 1998107827
nifedipine induced gingival hyperplasia. 19983182672
studies of non-disjunction of the major autosomes in drosophila melanogaster. ii. effects of dose-fractionation, low radiation doses, ems, and ageing. 1998108593
pvp: in gastroenterology. 1998106142
the evolution of the psro hospital review system.over the past several years, the psro hospital review system has evolved to such an extent as to merit re-examination of its objectives, accomplishments and potential, as well as the obstacles to success that still remain. the combination of review experience, political and funding pressures has reshaped the hospital review system. there is still controversy concerning the relative emphasis of the program on quality or costs, but there is no longer any question about the priority goal of the pro ...1998107373
comparison between ketotifen and dscg in bronchial challenge.a double-blind cross-over study showed that orally taken ketotifen and inhaled dscg have a comparable protective effect on allergen-induced bronchoconstriction. both drugs significantly inhibit the immediate bronchial reaction after a 3 day treatment with either 1 mg ketotifen or 20 mg dscg four times daily. late reactions, which occurred in three out of the ten patients, were inhibited in two of the three patients by ketotifen as by dscg.199997033
"kissing bug" bites. triatoma species as an important cause of insect bites in the southwest. 1999103687
clinical safety of flurazepam and midazolam during 14-day use in chronic insomniacs.data from evening questionnaires, reports of side effects, laboratory findings, and all-night respiratory measurements were collected on the 99 chronic insomniacs examined in this multicenter study. these data were used to compare the clinical safety and desirability of a benzodiazepine hypnotic with a very short half-life, midazolam 15 mg, with a hypnotic with a longer half-life, flurazepam 15 and 30 mg; both compounds were compared with a placebo control. there were 2 prestudy placebo nights f ...19992229460
risk factors for neural deficit in spinal tuberculosis.from 1975 through 1989, retrospective study of 155 patients with spinal tuberculosis was carried out at ramathibodi hospital to study predisposing factors to neural deficit and results of treatment. two groups of patients who had no neural deficit and had neural deficit were compared. clinical characteristics of the patients between the two study groups were similar with regard to sex, duration of symptoms, number of vertebrae involved, angle of gibbus deformity and erythrocyte sedimentation rat ...19991300362
carbodiimide-binding protein of h+-translocating atpase and inhibition of h+ conduction by dicyclohexylcarbodiimide.h+-translocating atpase, which catalyzes atp synthesis in biomembranes, is composed of a head piece (f1) and a membrane moiety (f0). using highly-purified f0 from a thermophilic bacterium ps3 (tf0), the following results were obtained. 1. inhibition by n,n'-dicyclohexylcarbodiimide (dccd) of h+ conduction through tf0 followed pseudo-first-order kinetics. the second-order rate constant for inhibitor-enzyme interaction was 5 times 10(3) m(-1)-min(-1). 2. h+ conductivity blocked by dccd was proport ...200033978
protein-calorie malnutrition impairs the anti-viral function of macrophages. 2000101986
an erythrocyte membrane-protein anomaly in march haemoglobinuria.in three patients with march haemoglobinuria a well-defined protein abnormality has been revealed by high-resolution sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis.200091785
[prevention of thrombosis by means of toning of the veins]. 200194860
the effect of repeated small doses of radiation on recovery from sub-lethal damage by chinese hamster cells irradiated in the plateau phase of growth.unfed plateau-phase cells have been irradiated with either single doses or up to ten fractions of x-rays 6 hours apart. the single-dose survival curve had an extrapolation number of 11-4, and the oxygen-enhancement ratio (o.e.r.) was 3-1. cells were exposed to multiple fractions of 200 rad or 150 rad in air and 600 rad or 450 rad in hypoxia. the resulting survival curves did not fit a multi-target, single-hit model of cell survival, being much steeper than that would predict. the curves were exp ...20011083845
a new approach to teaching differential diagnosis of oral soft tissue pathosis. 200194926
[cervical root avulsion presenting proximal segmental muscular atrophy of unilateral upper extremity].a 56-year-old woman noticed non-progressive weakness in the proximal part of the right upper extremity from her childhood. at the age of 37 years, she was diagnosed as "spinal muscular atrophy" by an orthopedic surgeon. at the age of 56, neurological examinations revealed muscular atrophy and weakness confined to the right deltoid, biceps brachii and brachioradialis together with minor sensory disturbance in the lateral side of the right shoulder and forearm without pyramidal sign in the lower e ...20011301331
[value of intravesically instilled oxybutynin in refractory bladder hyperactivity. study of 15 cases].15 patients with neurogenic detrusor hyperactivity refractory to oral anticholinergics received a daily intravesical instillation of 5 mg of oxybutinin for 6 days. an improvement was observed clinically in 10 cases and on urodynamic parameters (60% increase in bladder capacity, doubling of the volume inducing an urge to void) in 12 cases. the mechanism of action is discussed.20021302108
d-penicillamine as maintenance therapy for active chronic hepatitis. 2002122653
the bean bag chair and the pedodontic patient with cerebral palsy. 2002123868
[value (and limitations) of the rast fx5 in pediatric allergological practice].rast f x 5 (cap-system, pharmacia), an in vitro assay testing a mixture of 6 food antigens, was systematically applied to 400 children and adolescents with respiratory pathologies possibly of allergic origin. the clinical aspects of the 293 test-negative patients were compared with those of the 107 positive cases. furthermore, 84 positive sera were also evaluated against each of the 6 antigens regrouped in the f x 5. in this population with allergic respiratory diseases, the most frequently posi ...20031303592
[possibility of zoonotic cutaneous leishmaniasis infection of the population of muyun-kum (chu-talas interfluve)]. 2003149894
the role of a dentist in medicolegal problems. 2003298706
[acute renal insufficiency in the idiopathic nephrotic syndrome. observation of 4 cases]. 2003262267
[ige determination (rist, prist and others)]. 2004490927
projection arteriography and venography: initial clinical results with mr.motion currently limits the applications of magnetic resonance (mr) angiography in certain regions of the body. to overcome this problem, a series of breath-hold, two-dimensional, flow-compensated gradient-echo images were acquired. these images were then processed by means of the maximum intensity projection algorithm to produce projection angiograms. the method was evaluated in 10 healthy subjects and in 12 patients and validated by comparing conventional angiograms, contrast material-enhanced ...20042748814
projection arteriography and venography: initial clinical results with mr.motion currently limits the applications of magnetic resonance (mr) angiography in certain regions of the body. to overcome this problem, a series of breath-hold, two-dimensional, flow-compensated gradient-echo images were acquired. these images were then processed by means of the maximum intensity projection algorithm to produce projection angiograms. the method was evaluated in 10 healthy subjects and in 12 patients and validated by comparing conventional angiograms, contrast material-enhanced ...20042748814
job sharing: a viable option. 20041304937
[interaction between diazoxide and phenytoin]. 20042935845
[perspective of tuberculosis control--role of preventive chemotherapy (author's transl)].after a short review of measures for control and eradication of infectious diseases in general and especially of tuberculosis, the indications of chemoprophylaxis and preventive chemotherapy of tuberculosis are discussed. using results of a double-blind controlled trial on preventive chemotherapy in a high risk group (persons with fibrotic lung lesions), cost, benefit and side effects of preventive chemotherapy are analysed. preventive chemotherapy in high risk persons is an effective measure in ...2004516804
[prof. wolfgang presber--60 years old]. 2004395774
separation of creatine from arginine in biological fluids by thin-layer chromatography.creatine in biological fluids was estimated using a modified sakaguchi procedure. interference by arginine was eliminated by thin-layer chromatography.2004539794
better health through nursing is goal. 20041952401
better health through nursing is goal. 20041952401
smoking and natural immunity to tumours. 2004514150
moderation of morbidity following tonsillectomy and adenoidectomy: a study of awareness under anesthesia.sixty-seven children between the ages 3 and 10, undergoing tonsillectomy and adenoidectomy, were randomly assigned to one of 3 groups. therapeutic suggestions recited in english (n = 31), french (n = 19), or continuous white noise (n = 18) were repetitively administered by means of earphones in a double blind design. randomization to the english condition was associated with a more favorable outcome with respect to all parameters evaluated by physicians and nurses. however, statistical significa ...20042286510
effect of a fluoride solution on dentinal hypersensitivity.this two-phase experiment assessed the effects over time of a solution containing 1.09% sodium fluoride, .40% stannous fluoride, and .14% hydrogen fluoride (.717% fluoride solution, dentinbloc) on pain associated with dentinal hypersensitivity. during phase i, 30 subjects demonstrating dentinal hypersensitivity to a blast of cool air were divided into three double blind experimental groups. after baseline data were collected for all subjects, one group was instructed to apply the .717% fluoride ...20041304175
improving physical therapy students' clinical problem-solving skills: an analytical questioning model.the purpose of this study was to assess the effectiveness of a model for teaching problem-solving skills to first-year physical therapy students using the watson-glaser critical thinking appraisal (cta) and participant feedback. we used a pretest-posttest control group design. subjects were 31 first-year physical therapy students divided into a control group (n = 15) and an experimental group (n = 16). students in the experimental group used the problem-solving model during a four-week clerkship ...20052727067
choices. 20051069689
[treatment and prognosis of recurrent and metastatic carcinoma of the breast (author's transl)]. 20051063993
[epidemiology of collagen diseases. (1). screening of collagen diseases]. 20051169518
calorimetric validation of the caltrac accelerometer during level walking.the primary purpose of this study was to compare the caltrac accelerometer output with measured energy expenditure (ee). twenty-five volunteers (10 men, 15 women) walked on a level motor-driven treadmill at four different speeds (54, 81, 104, and 130 m.min-1) with the caltrac device affixed to the waistline. each of the four experimental trials lasted eight minutes, and the testing was completed within an hour. during the test, oxygen consumption (vo2) (in l.min-1 and in ml.kg-1.min-1) and nonpr ...20062727075
effects of a developmental physical therapy program on oxygen saturation and heart rate in preterm infants.to evaluate the physiologic responses of 14 preterm infants to physical therapy, pulse oximetry was used to measure the percentage of arterial oxygen saturation (sao2) and heart rate during baseline, intervention, and recovery phases. treatment consisted of six one-minute activities that were equally divided between the side-lying and supported-sitting positions. the order of position and activities was randomly varied. a one-way analysis of variance for repeated measures revealed no significant ...20062727071
spontaneous intramural dissection of the esophagus. 20062760439
identification and characterization of deoxyguanosine-crotonaldehyde adducts. formation of 7,8 cyclic adducts and 1,n2,7,8 bis-cyclic adducts.crotonaldehyde, a chemically reactive alpha,beta-unsaturated carbonyl compound, is an important industrial chemical and a ubiquitous environmental pollutant. it has been shown to be carcinogenic and mutagenic. we have studied the reaction of crotonaldehyde with nucleosides and 5'-mononucleotides and found three different types of adducts with deoxyguanosine and 2'-deoxyguanosine 5'-monophosphate. no adducts could be isolated either with nucleosides other than deoxyguanosine or with nucleotides o ...20061489932
cyclic changes in amphibian egg microvilli occur during the division cycle: implication of mpf.the microvilli (mv) of pleurodeles (amphibian) eggs were examined following fertilization and compared with those of artificially activated eggs and enucleated eggs using scanning and transmission electron microscopy. the mv pattern in fertilized eggs was found to undergo a cyclic transformation during the course of the first few division cycles. similar changes also occurred in the mv of artificially activated eggs and enucleated eggs. the reorganization of the mv was sensitive to cycloheximide ...20061769344
magnesium deficiency in chronic schizophrenia. 20061809739
grants to help increase us children's immunity. 20061538548
intraocular tumor formation of rb reconstituted retinoblastoma cells.it has been reported that replacement of a functional retinoblastoma (rb) gene in rb defective weri-27 retinoblastoma cells results in complete loss of their tumorigenic potential in nude mice following s.c. injection. we have repeated the identical studies and found that although tumors did not develop s.c., the rb reconstituted cells, either soon after rb virus infection or after long term cultivation, consistently produced tumors when injected intraocularly. these tumor cells, when reestablis ...20061868470
intraocular tumor formation of rb reconstituted retinoblastoma cells.it has been reported that replacement of a functional retinoblastoma (rb) gene in rb defective weri-27 retinoblastoma cells results in complete loss of their tumorigenic potential in nude mice following s.c. injection. we have repeated the identical studies and found that although tumors did not develop s.c., the rb reconstituted cells, either soon after rb virus infection or after long term cultivation, consistently produced tumors when injected intraocularly. these tumor cells, when reestablis ...20061868470
systemic adverse reactions to glaucoma medications. 20062568979
growth hormone control of tissue protein metabolism in dwarf mice: enhancement by a monoclonal antibody.monoclonal antibody (mab) to gh has been shown to increase the anabolic response induced by the hormone in individual tissues of dwarf mice. dwarf mice were treated with gh at a low and a high dose (2.5 and 50 mu/day respectively), with and without complexing to an mab. treatment was for 7 and 14 days, at which times protein synthesis rates in skeletal muscle, liver and heart were determined from incorporation of labelled phenylalanine following injection of a flooding dose. the mab potentiated ...20061564421
ferritin cannot release iron in vivo if there is no ferritin present. 20061459489
[amalgam?]. 20072238922
[amalgam?]. 20072238922
[socio-occupational rehabilitation of patients with heart transplants. study of 43 cases]. 20073060708
the mechanisms of exercise provocation of supraventricular tachycardia.treadmill exercise tests, electrophysiologic studies, and isoproterenol infusions were performed in 14 patients with exercise provocable supraventricular tachycardia to delineate the mechanisms of exercise provocation of paroxysmal supraventricular tachycardia. treadmill exercise tests reproducibly provoked supraventricular tachycardia in all patients. supraventricular tachycardia similar to that provoked by exercise occurred spontaneously during isoproterenol infusions in 9 of 11 patients teste ...20072565683
imaging the child with multiple trauma. 20073246382
[microradiographic investigations of carious changes in the enamel in the ground sections made perpendicularly to tooth axis].carious changes in the enamel in the undermineralized ground sections made perpendicularly to tooth axis were investigated using microradiography. by this way, relationship between carious invasion and the enamel lamellae and tuft, which has been not able to be examined in the longitudinal ground sections, could be clarified. 1) direction of progress of demineralization and contour of demineralization front in the enamel are closely related to arrangement of enamel prisms. this findings strongly ...20072134968
[electrophoretic studies of the composition of peripheral mononuclear cells during operations with extracorporeal circulation].the increased incidence of infections after operations can be connected with changes of the immunocompetent cells. mononuclear blood-cells were investigated by means of the cell electrophoresis during and after operations under the extracorporeal circulation, because electrophoretically different cells correlate with several immunological phenotypes. a heavy decrease of the electrophoretic quick mobility cell population was found out on the first postoperative day above all. this change allows i ...20072219997
the metabolic cancer therapy of harold w. manner, ph.d. 20073011226
relationship of cerebral blood flow and cerebral swelling to outcome in patients with acute fulminant hepatic failure. 20072063458
the area under the roc curve and its competitors.the area under the receiver operating characteristic (roc) curve is a popular measure of the power of a (two-disease) diagnostic test, but it is shown here to be an inconsistent criterion: tests of indistinguishable clinical impacts may have different areas. a class of diagnosticity measures (dms) of proven optimality is proposed instead. once a regret(-like) measure of diagnostic uncertainty is agreed upon, the associated dm is uniquely defined and, indeed, calculable from the roc curve configu ...20071865785
adverse events temporally associated with immunizing agents: 1987 report. 20072804852
regulation of lipoprotein lipid transfer by unesterified cholesterol.elevated lipoprotein unesterified cholesterol altered differentially the transfer of cholesteryl esters and triacylglycerols. this resulted in increased mass transfer of cholesteryl esters from hdl to vldl coupled with an equimolar transfer of triacylglycerol from vldl to hdl.20082654777
bacterial meningitis with initial normal cerebrospinal fluid findings.seven pediatric patients with bacterial meningitis but with initial normal cerebrospinal fluid (csf) findings are presented. they represent 6.5% of all cases with bacterial meningitis seen at our medical center during a 5-year period. in all cases, the duration of symptoms before the initial lumbar puncture was short (6-24 h). the case-fatality rate was 3/7 (43%) compared with 10/100 (10%) among children with abnormal initial csf, despite early initiation of antibiotics. bacterial meningitis wit ...20082708023
oral habits in common between tension headache and non-headache populations.previous research has suggested a relationship between migraine pain and oral habits. the present study was designed as a replication of a prior study that found self-reported higher frequencies of certain oral habits in migraine as opposed to tension headache and non-headache groups. three groups of subjects (common migraine, tension headache and non-headache) were given a single questionnaire in which five oral habits (i.e. teeth clenching, jaw jutting, cupping the chin in the hand, and restin ...20082746407
[active thermography in the diagnosis of breast cancer].three procedures of active thermography were used in examination of 1301 patients with stage i-iii breast tumors. the evaluation of their diagnostic effectiveness established their evident advantages over any method of passive thermography. application of active procedures increased diagnostic accuracy by 9-15% and decreased the number of false negative results by 4-10%.20082596067
cell proliferation in the olfactory bulb of adult freshwater teleosts.the olfactory bulb of adult specimens of carassius auratus was subjected to an autoradiographic study using [3h]thymidine. adult specimens of carassius auratus, barbus meridionalis, cyprinus carpio and salmo gairdneri were also studied using light and electron microscopy. cells were found undergoing mitotic division with two characteristic locations: a group can be seen near to the ventricle or ventricular recess; these cells can be identified as granule cells or precursors of granule cells. oth ...20082606770
theory of local loss of blood and fluid. by alfred blalock, 1940. 20082645078
[many indications from radiographic examination]. 20082640839
tic disorders in childhood (and beyond).tic disorders are classified into three main categories: transient (duration more than 1 month but less than 1 year), chronic (duration more than 1 year), and tourette's syndrome (multiple motor and vocal tics lasting more than 1 year to life). typically, symptoms increase with emotional stress, diminish with distraction or concentration, and disappear during sleep. because of the risks involved and the lack of any truly curative value, drug therapy should be used only when tics are seriously di ...20082662159
major histocompatibility complex class i-restricted activation of cloned t cells by a soluble protein in the absence of accessory cells.a t-cell clone, 10bk.1, was established from the draining lymph nodes of (b10 x b10.br)f1 mice immunized with ovalbumin (ova) according to standard protocols. upon coculture with the antigen, 10bk.1 cells reacted by production of lymphokines and by proliferation despite the absence of additional antigen-presenting cells. these t cells do not express major histocompatibility complex (mhc) class ii molecules on the cell surface as assessed on the basis of several criteria: by cytofluorometric anal ...20092784568
[the clinical value of preoperative staging of bladder and prostatic cancers with nuclear magnetic resonance and computerized tomography].to evaluate the diagnostic value of preoperative staging of bladder cancer and cancer of the prostate, ct and nmr scans of 45 histologically defined tumors of the bladder and the scans of 24 patients with radical prostatectomy were compared. lack of extravesical spread was imaged correctly by nmr in all cases of urothelial cancer (pt1-pt3a). ct diagnosis failed in 39%. false-negative results were obtained in 2 of 5 invading tumors (pt3b) by nmr and in 3 of 5 by ct. extraglandular spread of cance ...20092718295
[veno-occlusive disease of the liver (a review of the literature)]. 20092678753
pharmacist has responsibility to warn patients of drug interactions. 20092712029
immunochemical comparison of high molecular weight angiotensinogen from amniotic fluid, plasma of men, and plasma of pregnant women.a high molecular weight form of angiotensinogen (hmra) is present in low quantities in plasma from men, in moderate quantities in plasma from pregnant women, and in larger quantities in amniotic fluid. it was shown that immobilized igg from anti-low molecular weight angiotensinogen (lmra) sera effectively removed hmra from all three sources. immunoblots of sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds-page) using anti-lmra sera showed that hmra from each of the three sources co ...20092719824
[myasthenia gravis and pregnancy: review of the literature and report of 6 cases occurring in 5 patients].the authors report six cases of myasthenia gravis during pregnancy. three patients experienced increasing severity of their disease and one death occurred in the puerperium. the infants were born with no evidence of neonatal myasthenia. the patients should be closely monitored during labor and puerperium. this disease is characterized by unpredictable exacerbations, and the association of myasthenia gravis and pregnancy increases the risk for the patient.20092699532
write your biography to get an interview. 20092752317
insensitivity, limited joint mobility, and plantar ulcers in patients with diabetes mellitus.the purpose of this study was to determine whether differences in sensation, ankle dorsiflexion (df), and subtalar joint (stj) motion exist between 1) diabetic patients with a history of plantar ulcer (dmw group), 2) diabetic patients without a history of plantar ulcer (dmwo group), and 3) a nondiabetic control group (ndc group). there were 23, 23, and 24 subjects in the respective groups. the mean age for each group was 58, 63, and 60 years, respectively. the mean df for each group was 2, 5, an ...20092727069
percutaneous transluminal coronary angioplasty of the "culprit lesion" for management of unstable angina pectoris in patients with multivessel coronary artery disease.the efficacy of 1-vessel percutaneous transluminal coronary angioplasty (ptca) directed at the presumed angina-producing stenosis, or "culprit lesion," in the treatment of unstable angina pectoris and multivessel coronary artery disease (cad) was assessed in 27 patients with unstable angina refractory to optimal medical therapy. eighteen patients had 2-vessel and 9 had 3-vessel cad. the culprit lesion was identified in all patients by analysis of the qualitative appearance of the coronary lesion ...20102944366
cell lineage and segmentation in the leech.segments in the leech arise by the proliferation of longitudinally arrayed bandlets of blast cells derived from ten identifiable embryonic stem cells, two m, two n, four o/p and two q teloblasts. in each bandlet, older blast cells lie ahead of those born later. by using microinjected cell lineage tracers it was shown previously that the teloblasts give rise to characteristic cell patterns made up of segmentally iterated complements of progeny designated as m, n, o, p and q kinship groups. when a ...20102869529
recurrent parotid gland enlargement as an initial manifestation of sjögren syndrome in children.recurrent parotid gland enlargement is a common disorder in children, while that of auto-immune aetiology is rare. three children with recurrent parotid swelling had autoantibodies including antinuclear antibody, anti-ss-a (sjögren syndrome-a), ss-b (sjögren syndrome-b) antibodies and rheumatoid factor, abnormal sialograms and lymphocytic infiltration of salivary glands, which were consistent with sjögren syndrome. initially, all three lacked symptoms of keratoconjunctivitis sicca. during follow ...20102920746
effect of beta blockers on vascular resistance in systemic hypertension.over 20 years ago, it was established that beta blockers could reduce high blood pressure. currently, several beta blockers with different ancillary properties are available. they all have the property of blocking beta 1 receptors but differ from each other in a number of other respects: they may or may not block beta 2 receptors in low doses (beta 1 = receptor selectivity); they may or may not possess varying degrees of partial agonist activity, also known as intrinsic sympathomimetic activity ...20102883873
[imuthiol treatment of a symptom complex associated with acquired immunodeficiency syndrome. initial results after 2-3 years]. 20102831532
transient hypertension after two phenylpropanolamine diet aids and the effects of caffeine: a placebo-controlled follow-up study.reports of severe adverse reactions following the ingestion of single (75 mg) or double doses of the sympathomimetic drug phenylpropanolamine (ppa), with and without caffeine, prompted us to undertake a study of the effects of five drug preparations (75 mg ppa, 150 mg ppa, 75 mg ppa plus 400 mg caffeine, 400 mg caffeine, and placebo) in 16 resting, normotensive subjects. the study was of a double-blind, randomized, crossover design. each subject consented to take the five drug preparations on di ...20102929629
mosquito breeding in water meter chambers. 20102863184
[study of the rhythm of spasms in an athletic cohort. its relation to muscle pathology]. 20102949468
triamterene and the kidney. 20102868346
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