Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| female urinary chemosignals influence scent-marking behavior in male mongolian gerbils (meriones unguiculatus). | the influence of females on the amount of scent-marking behavior displayed by male mongolian gerbils was investigated. males isolated from females scent mark at a low level which increases more than two-fold if females are present in the room for three weeks without direct contact with the males. a similar increase is obtained by application of pooled female urine directly onto the males' noses. | 1985 | 3832671 |
| chemotactic activity of hydroxyalkenals on rat neutrophils. | previous results from our laboratory showed that in vitro 4-hydroxyoctenal, 4-hydroxynonenal (hne) and 4-hydroxytetradecenal elicit a neutrophil chemotactic response in the presence of albumin. data presented here indicate that other hydroxyalkenals (4-hydroxyundecenal and 4-hydroxy-pentadecenal) also exert a chemotactic attraction on rat pleural neutrophils. the different aldehydes tested show a wide activity-concentration range, the most powerful being 4-hydroxyoctenal. unlike most chemoattrac ... | 1985 | 3839769 |
| [synthesis of vitamin d in the skin]. | 1985 | 3898049 | |
| immunology and immunopathology of malignant catarrhal fever. | 1985 | 3917220 | |
| monoclonal antibodies against mouse gamma-interferon inhibit tumoricidal macrophage activation by t lymphocytes. | a monoclonal antibody, an-18.17.24, specific for murine interferon-gamma (ifn-gamma) was produced by immunizing wistar rats with ifn-gamma secreted by a t-cell lymphoma, l12-r4, upon stimulation with phorbol myristic acetate (pma). antiviral activity as well as tumoricidal activation induced by pma-stimulated l12-r4 cell supernatant or by con a-stimulated normal spleen cells were neutralized at the same extent by an-18 monoclonal antibody. moreover, depletion experiments showed that inhibition o ... | 1985 | 3930308 |
| monoclonal antibodies against mouse gamma-interferon inhibit tumoricidal macrophage activation by t lymphocytes. | a monoclonal antibody, an-18.17.24, specific for murine interferon-gamma (ifn-gamma) was produced by immunizing wistar rats with ifn-gamma secreted by a t-cell lymphoma, l12-r4, upon stimulation with phorbol myristic acetate (pma). antiviral activity as well as tumoricidal activation induced by pma-stimulated l12-r4 cell supernatant or by con a-stimulated normal spleen cells were neutralized at the same extent by an-18 monoclonal antibody. moreover, depletion experiments showed that inhibition o ... | 1985 | 3930308 |
| the near infrared (nir) absorption band of cytochrome aa3 in purified enzyme, isolated mitochondria and in the intact brain in situ. | 1985 | 3008514 | |
| synthesis of eicosanoids by tissues of the synovial joint during the development of chronic erosive synovitis. | 1986 | 3008530 | |
| markers for estimating digesta flow in pigs and the effects of dietary fiber. | effects of diluting the energy content of a corn-soybean meal diet with either alfalfa meal or corn cobs on nutrient digestibility and rate of passage of feed residues and particle markers were measured in crossbred (yorkshire x landrace x chester white x large white) barrows with a mean body weight of about 80 kg. the excretion pattern in the feces of cr-mordanted diet and of rare earths initially bound individually to the mixed diet or to the corn or soybean meal suggested a model having a sin ... | 1986 | 3021704 |
| markers for estimating digesta flow in pigs and the effects of dietary fiber. | effects of diluting the energy content of a corn-soybean meal diet with either alfalfa meal or corn cobs on nutrient digestibility and rate of passage of feed residues and particle markers were measured in crossbred (yorkshire x landrace x chester white x large white) barrows with a mean body weight of about 80 kg. the excretion pattern in the feces of cr-mordanted diet and of rare earths initially bound individually to the mixed diet or to the corn or soybean meal suggested a model having a sin ... | 1986 | 3021704 |
| reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices. | slice preparations of the developing rat cerebellum were used to investigate the light and electron microscopic correlates of reversible and irreversible neuronal injury caused by the neurotoxic excitatory amino acid receptor agonists, kainate and n-methyl-d-aspartate. the slices were examined after various periods of exposure to the agonists (up to 30 min) with or without a 90 min recovery period in agonist-free medium. n-methyl-d-aspartate (100 microm) caused necrosis of deep nuclear neurons a ... | 1986 | 3526173 |
| reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices. | slice preparations of the developing rat cerebellum were used to investigate the light and electron microscopic correlates of reversible and irreversible neuronal injury caused by the neurotoxic excitatory amino acid receptor agonists, kainate and n-methyl-d-aspartate. the slices were examined after various periods of exposure to the agonists (up to 30 min) with or without a 90 min recovery period in agonist-free medium. n-methyl-d-aspartate (100 microm) caused necrosis of deep nuclear neurons a ... | 1986 | 3526173 |
| neurotropin increases in vitro life span of human fibroblasts. | fibroblasts isolated from human fetal tissues (skin, lung and heart) exhibited the following population doubling levels (pdl): about 40 pdl for skin; 60 pdl for lung; 10 pdl for heart. neurotropin extract from vaccinia-virus infected skin tissues of rabbits increases the growth rate of the fibroblast when added to the old lung cell culture (pdl 40, 70% of the maximum life span) but not when added to the young lung (pdl 5, 8% of the maximum life span). neurotropin (40 or 80 micrograms/ml) increas ... | 1986 | 3736135 |
| control of heme synthesis during friend cell differentiation: role of iron and transferrin. | in many types of cells the synthesis of delta-aminolevulinic acid (ala) limits the rate of heme formation. however, results from our laboratory with reticulocytes suggest that the rate of iron uptake from transferrin (tf), rather than ala synthase activity, limits the rate of heme synthesis in erythroid cells. to determine whether changes occur in iron metabolism and the control of heme synthesis during erythroid cell development friend erythroleukemia cells induced to erythroid differentiation ... | 1986 | 3464611 |
| pain, increasing girth in healthy japanese man. | 1986 | 3021791 | |
| pain, increasing girth in healthy japanese man. | 1986 | 3021791 | |
| endocytosis of proteoheparan sulfate by cultured skin fibroblasts. | endocytosis by cultured human skin fibroblasts of 35so4(2-)-labeled proteoheparan sulfate from fibroblast secretions was quantitatively investigated. at a constant dose of proteoheparan sulfate, uptake and subsequent intracellular degradation but not binding to the cell membrane increased with time. compared with the endocytosis of total secreted proteoglycans containing predominantly a small proteodermatan sulfate, uptake of proteoheparan sulfate was 5- to 20-fold lower. nevertheless, uptake of ... | 1986 | 2943303 |
| morphine or capsaicin administration alters the secretion of beta-endorphin into the hypophysial portal vasculature of the rat. | immunoreactive beta-endorphin (ir-beta-end) concentrations were measured in the hypophysial portal plasma of the male rat under urethane anesthesia. on the basis of immunochemical studies and gel filtration chromatography it appears that ir-beta-end in rat hypophysial portal plasma is primarily beta-endorphin (beta-end) and not beta-lipotropin (beta-lph). in addition, much of the ir-beta-end in portal plasma may be of pituitary origin since acute hypophysectomy resulted in approximately an 80% d ... | 1986 | 2944026 |
| analgesic effectiveness of topically applied dynorphin on human dental pulp. | 1986 | 2876436 | |
| the ascending projections of the dopaminergic neurons of the substantia nigra, zona reticulata: a combined retrograde tracer-immunohistochemical study. | the efferent projections of the dopaminergic neurons in the zona reticulata of the substantia nigra were examined using a combined retrograde tracer-immunohistochemical method. these dopamine (da) neurons were found to project exclusively to striatal targets in a topographically defined fashion. the zona reticulata da neurons do not innervate mesolimbic or mesocortical dopaminergic terminal fields, nor do they project to the superior colliculus or the ventromedial thalamic nucleus. these data su ... | 1986 | 2879262 |
| formation of mboii vectors and cassettes using asymmetric mboii linkers. | class-iis restriction endonucleases such as mboii cleave dna at a specified distance away from their recognition sequences. this feature was exploited to cleave dna at previously inaccessible locations by preparing special asymmetric linker/adapters containing the mboii recognition sequence. these could be joined to dna fragments and subsequently cleaved by mboii. attachment of a 3' phosphate to one of the two different oligodeoxynucleotides comprising the asymmetric duplex prevented ligation at ... | 1987 | 2820843 |
| formation of mboii vectors and cassettes using asymmetric mboii linkers. | class-iis restriction endonucleases such as mboii cleave dna at a specified distance away from their recognition sequences. this feature was exploited to cleave dna at previously inaccessible locations by preparing special asymmetric linker/adapters containing the mboii recognition sequence. these could be joined to dna fragments and subsequently cleaved by mboii. attachment of a 3' phosphate to one of the two different oligodeoxynucleotides comprising the asymmetric duplex prevented ligation at ... | 1987 | 2820843 |
| chronic cardiac toxicity after inhalation of 1,1,1-trichloroethane. | two patients showed evidence of chronic cardiac toxicity after repeated exposure to 1,1,1-trichloroethane. in both cases there was circumstantial evidence of a deterioration after routine anaesthetic use of the related compound halothane. an adolescent boy who sniffed trichloroethane presented with multiple ventricular arrhythmias during tonsillectomy. follow up showed mild chronic left ventricular impairment. a 54 year old man had repeated industrial exposure to trichloroethane and deteriorated ... | 1987 | 3105712 |
| chronic cardiac toxicity after inhalation of 1,1,1-trichloroethane. | two patients showed evidence of chronic cardiac toxicity after repeated exposure to 1,1,1-trichloroethane. in both cases there was circumstantial evidence of a deterioration after routine anaesthetic use of the related compound halothane. an adolescent boy who sniffed trichloroethane presented with multiple ventricular arrhythmias during tonsillectomy. follow up showed mild chronic left ventricular impairment. a 54 year old man had repeated industrial exposure to trichloroethane and deteriorated ... | 1987 | 3105712 |
| [experimental infection of sarcocystis suihominis in pigs]. | 1987 | 3113762 | |
| human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation. | purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ... | 1987 | 2963123 |
| pulsatile release of antipyretic neuropeptide alpha-msh from septum of rabbit during fever. | the effects on fever of central administration of alpha-melanocyte-stimulating hormone (alpha-msh) and its antiserum, the specific increase in central concentration of alpha-msh during fever, and related results indicate that this neuropeptide is important to central nervous system (cns) regulation of the febrile response. the present experiments were designed to establish whether alpha-msh is released from septal tissue during fever and, if so, in what temporal course relative to the febrile re ... | 1987 | 3591986 |
| the binding of decomposition products of udp-galactose to the microsomes and polyribosomes isolated from rat liver. | udp-d-[u-14c]galactose is decomposed to [u-14c]galactose-1-phosphate and [u-14c]galactose by rat liver microsomal and crude polyribosomal fractions, under conditions commonly used to assay of glycosyltransferase activities. udp-d-[u-14c]galactose, at neutral ph, is also chemically degraded to the [u-14c]galactose-1,2-cyclic phosphate. the 1,2-cyclic phosphate derivative of galactose also exists in the commercial udp-d-[u-14c]galactose. it is a very important finding that products of the udp-d-[u ... | 1987 | 3675917 |
| non-invasive estimation of afferent inputs for postural stability under low levels of alcohol. | the maintenance of human equilibrium is a complex process. several physiological systems provide afferent information for postural stabilization. this study describes a noninvasive methodology to estimate the relative roles of interacting afferent inputs relevant for postural control. a multiaxis force platform in conjunction with specially designed test procedure provided semi-quantitative insight into the roles of vision, proprioceptors and vestibular apparatus in controlling postural sway whe ... | 1987 | 3688583 |
| in vivo inorganic chemistry of technetium cations. | technetium-99m cations are of interest because of their potential use as myocardial perfusion imaging agents. these species can undergo in vivo reactions which markedly affect their biodistribution patterns. four such cases of reactions are presented and discussed: (1) simple ligand substitution; (2) metal centered redox processes; (3) reactions of coordinated ligands; (4) outer sphere association reactions. new experimental techniques appropriate for investigating these reactions at the 10(-10) ... | 1987 | 3305808 |
| activity of a partially purified human bcgf on murine assays for b-cell stimulatory factors. i. bcgf ii-like activity of human bcgf. | to further characterize a human b-cell growth factor (bcgf) produced by phytohemagglutinin (pha) p-stimulated peripheral blood t cells, a partially purified preparation of this material was tested in a number of murine assays for b-cell stimulatory factors (bsf). human bcgf lacked murine bsf-1 activity as assessed via the induction of polyclonal proliferation of anti-igm-stimulated murine b cells; however, this material consistently augmented the proliferative response of murine b cells to anti- ... | 1987 | 3499989 |
| protective effects of the thromboxane receptor antagonists bm 13.177 and bm 13.505 against u 46619-induced sudden death in rats. | the purpose of this study was to evaluate the pharmacology and pharmacodynamics of the thromboxane receptor antagonists, bm 13.177 and bm 13.505, for prevention of u 46619-induced sudden death in anesthetized male sprague-dawley rats. the injection of u 46619 (100 micrograms/kg i.v.) produced sudden death typically between 5 and 15 min. administration of 0.01 mg/kg bm 13.505 (i.v.) 0.1 h prior to the u 46619 challenge did not protect against sudden death, while doses of 0.03 mg/kg or greater pro ... | 1988 | 3406046 |
| ethical considerations of the new reproductive technologies. by the ethics committee (1986-87) of the american fertility society in light of instruction on the respect for human life in its origin and on the dignity of procreation issued by the congregation for the doctrine of the faith. | in september 1986, the american fertility society issued a report, ethical considerations of the new reproductive technologies, setting forth the then-held ethical position of the society on the various new reproductive technologies. in 1987, the congregation for the doctrine of the faith issued the instruction on the respect for human life and its origin and on the dignity of procreation. while both documents state that very similar moral criteria were used to derive ethical positions with resp ... | 1988 | 3276566 |
| diabetic embryopathy and fuel-mediated organ teratogenesis: lessons from animal models. | the growing recognition that faulty maternal metabolism during early organogenesis may be implicated in the increased incidence of birth defects in pregnancies complicated by diabetes has prompted worldwide efforts to institute improved preconceptional metabolic regulation. however, the failure to identify the periods of greatest risk for diabetic embryopathy, the mediating teratogen(s), and the underlying mechanisms have complicated attempts to establish precise therapeutic guidelines and targe ... | 1988 | 3053387 |
| isolation of enzymes with novel capabilities for use in clinical analysis. | 1988 | 3067633 | |
| isolation of enzymes with novel capabilities for use in clinical analysis. | 1988 | 3067633 | |
| prostacyclin biosynthesis and phospholipase activity in hypoxic rat myocardium. | phospholipid metabolism was studied in rat myocardial slices that were incubated under normoxia or hypoxia for up to 24 hours. phospholipid degradation was prominent in hypoxic myocardium, particularly phosphatidylcholine, which markedly decreased after 24 hours of hypoxia. in contrast, lysophosphatidylcholine increased. the mechanism of phospholipid degradation in hypoxic myocardium was studied. the highest activity for phospholipase a2 among subcellular fractions was found in microsomal fracti ... | 1988 | 3133132 |
| interaction of acidic isoferritins with human promyelocytic hl60 cells. | we have used undifferentiated human promyelocytic hl60 cells to study the binding of radioiodinated human ferritin in vitro. specific binding of human heart ferritin could be demonstrated at 37 degrees c, whereas no binding of liver ferritin could be found. the uptake of labelled heart ferritin was abolished by incubation at 4 degrees c, by prior treatment of the hl60 cells with pronase and by the addition of human plasma to the medium. on the other hand, the addition of excess unlabelled human ... | 1988 | 3165673 |
| blastocystis hominis: clinical and therapeutic aspects. | 1988 | 3176148 | |
| the effect of alcoholic beverages on iron and zinc metabolism in the rat. | 1. male wistar rats (approximately 200 g) were given distilled water and a semi-synthetic control diet for 6 d. on day 7, 37 kbq 65zn were administered intramuscularly and the rats were given distilled water, beer, cider, red wine, whisky or ethanol as their only source of fluid. the wine, whisky and ethanol were diluted so that each of the beverages contained a similar ethanol concentration (approximately 30 g/l). food and fluid intake, growth rate and whole-body 65zn were measured regularly ov ... | 1988 | 3196669 |
| frequency of fimbriation of nontypable haemophilus influenzae and its ability to adhere to chinchilla and human respiratory epithelium. | to date, we have examined nearly 60 clinical isolates of nontypable haemophilus influenzae (26 nasopharyngeal, 33 from middle ear effusions) and have found that 100% were fimbriated. the percentage of cells bearing fimbriae within each isolate varied from less than 10 to 100%, with fimbriae being either peritrichous or bipolar in distribution. fimbriae were approximately 2.4 to 3.6 nm in width; however, there was a high degree of variability in both length and number of fimbriae per individual b ... | 1988 | 2892792 |
| characterization of an aeromonas hydrophila strain isolated on a septicemic out-break in a fish-farm of spain. | an aeromonas hydrophila strain (ah-3) was isolated from a septicemic out-break on a gold-fish farm near barcelona (spain). on the bases of their virulence and surface characteristics was classified as moderate to weakly virulent. | 1988 | 3271064 |
| regulatory functions of protein phosphorylation in meiotic maturation of mouse oocytes in vitro. | 1988 | 2853366 | |
| comparison of adrenal medullary, carotid body and pc12 cell grafts in 6-ohda lesioned rats. | the survival and functional properties of dispersed cell implants of catecholaminergic cells obtained from the peripheral nervous system of adult rats (adrenal medulla and carotid body glomus cells) and pc12 cells from a rat pheochromocytoma cell line were examined following transplantation into the striatum of the adult rat. the host animals, all with unilateral 6-hydroxydopamine (6-ohda) nigrostriatal lesions, were divided into 5 groups: (1) pc12 cells transplanted into cyclosporin-a treated h ... | 1988 | 2896533 |
| regulatory functions of protein phosphorylation in meiotic maturation of mouse oocytes in vitro. | 1988 | 2853366 | |
| a novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle ca2+ channels. | since the discovery of endothelium-dependent vasodilation, vascular endothelium has been recognized as an important functional unit contributing to the regulation of vascular tonus. recent purification, structure determination and molecular cloning of a novel peptidergic vasoconstrictor, endothelin, from the culture supernatant of porcine aortic endothelial cells has further substantiated this concept. starting from a large quantity of serum-fee endothelial cell-conditioned medium, endothelin wa ... | 1988 | 2853725 |
| obstetrical medication and the human newborn: the influence of alphaprodine hydrochloride on visual behaviour. | the visual habituation of two groups of newborn infants was tested at a mean age of 2.9 days with large achromatic squares of varying luminance. mothers of the infants in one group received no medication during labour; mothers in the second group received a single dose of the synthetic narcotic alphaprodine hydrochloride. the two groups did not differ in the number of trials to reach the criterion, but newborns in the no-medication group fixated the stimuli for much longer periods than did infan ... | 1989 | 2806744 |
| effects of human pth-related peptide and human pth on cyclic amp production and cytosolic free calcium in an osteoblastic cell clone. | recently, human parathyroid hormone-related peptide (hpthrp) has been purified and its amino acid sequence determined. within the amino-terminal 13 residues of hpthrp, 8 amino acids were found homologous between hpthrp and human pth (hpth). this peptide was reported to stimulate cyclic amp (camp) production in osteoblastic cell lines (umr106 and ros17/2.8). however, whether or not this peptide affects another second messenger, i.e., cytosolic free calcium ([ca2+]i), in osteoblasts has not yet be ... | 1989 | 2546638 |
| phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-hiv activity. | oligodeoxynucleotides with a phosphorus atom in which one of the non-bridging oxygen atoms is substituted by selenium were prepared and investigated with respect to their antisense properties. a general synthesis of phosphoroselenoate analogs of oligonucleotides is described using potassium selenocyanate as the selenium donor. the compounds, characterized by 31p nmr, were shown to decompose to phosphate with a half-life of ca. 30 days. melting temperatures of duplexes between poly(ra) or poly(ri ... | 1989 | 2682524 |
| in vivo dna cross-linking by cyclophosphamide: comparison of human chronic lymphatic leukemia cells with mouse l1210 leukemia and normal bone marrow cells. | alkaline elution was done on a variety of cells following cyclophosphamide (cy) treatment in vivo. cells used were l1210 leukemia, normal mouse bone marrow, and peripheral blood cells obtained from a patient with chronic lymphatic leukemia (cll). endpoints used were determination of single strand breaks, dna-dna interstrand and dna-protein cross-links. after treatment of mice with cy (4 mg/mouse), low levels of single strand breaks were observed in both l1210 leukemia and cdf1 normal bone marrow ... | 1989 | 2731167 |
| accurate and efficient rna polymerase iii transcription in a cell-free extract prepared from ascaris suum embryos. | high-speed supernatant (s100) extracts derived from homogenized ascaris suum embryos efficiently transcribe added rna polymerase iii templates including cloned 5s rrna genes of the filarial parasite brugia malayi. several criteria, including two-dimensional rnase t1 oligonucleotide fingerprint analysis, indicate that in vitro transcription is accurately initiated and terminated. | 1989 | 2747746 |
| the influence of endogenous and exogenous factors on the course and the results of experimental work with human tumor tissue on athymic nude rodents. | 1989 | 2749469 | |
| twenty-year comparison of the human allograft and porcine xenograft. | this study compares a retrospective consecutive series of human allografts and concurrent porcine xenografts implanted over a 10-year interval. there were 571 allograft valves and 1,351 xenograft valves implanted in the aortic and mitral position with mean follow-up of 12.8 years for the allografts and 6.2 years for the xenografts. this study compares the incidence of structural deterioration over long-term follow-up. we found that there was no significant difference between four manufacturers o ... | 1989 | 2774760 |
| ontogeny of androgen receptors in fetal guinea pig brain. | sexual differentiation of the guinea pig brain is androgen dependent. to understand the cellular mechanisms of androgen action, we studied the ontogeny of cytosolic (arc) and nuclear (arn) androgen receptors in the brains and anterior pituitaries of fetal, neonatal, and adult guinea pigs. using cytosol from the hypothalamus-preoptic area-amygdala-septum of 60- to 65-day fetuses and nuclear preparations from 6-day-old neonates treated with testosterone propionate, validation studies revealed an a ... | 1989 | 2804213 |
| ontogeny of androgen receptors in fetal guinea pig brain. | sexual differentiation of the guinea pig brain is androgen dependent. to understand the cellular mechanisms of androgen action, we studied the ontogeny of cytosolic (arc) and nuclear (arn) androgen receptors in the brains and anterior pituitaries of fetal, neonatal, and adult guinea pigs. using cytosol from the hypothalamus-preoptic area-amygdala-septum of 60- to 65-day fetuses and nuclear preparations from 6-day-old neonates treated with testosterone propionate, validation studies revealed an a ... | 1989 | 2804213 |
| cytotoxicity and effect on mutagenicity of buffers in a microsuspension assay. | we have examined the effects of three buffers--vogel-bonner minimal e (vbm) and 0.15 and 0.015 m sodium phosphate, ph 7.4--and two concentrations of overnight cells (5x and 10x) on the mutagenicity of two pure compounds and two complex mixtures in strain ta98 using a modification of a microsuspension assay developed by kado et al. (mutation research 121:25-32, 1983). the assay was performed by adding 50 microliters of cell concentrate of an overnight culture of ta98 resuspended in the appropriat ... | 1989 | 2575290 |
| characterization of the rela1 mutation and a comparison of rela1 with new rela null alleles in escherichia coli. | the most widely studied "relaxed" mutant of the rela locus, the rela1 allele, is shown here to consist of an is2 insertion between the 85th and 86th codons of the otherwise wild-type rela structural gene, which normally encodes a 743-amino acid (84 kda) protein. the rela protein is a ribosome-dependent atp:gtp (gdp) pyrophosphoryltransferase that is activated during the stringent response to amino acid starvation and thereby occasions the accumulation of guanosine 3',5'-bispyrophosphate (ppgpp). ... | 1989 | 2556396 |
| attenuation of defensive threat and attack in wild rats (rattus rattus) by benzodiazepines. | a battery of tests designed to elicit reactions to a variety of non-painful threat stimuli was used to study the effects of chlordiazepoxide (5-20 mg/kg), diazepam (1-5 mg/kg) and midazolam (1-10 mg/kg) on the defensive repertoire of wild rattus rattus. the most consistent effect of benzodiazepine treatment, across compounds and tests, was a marked reduction in defensive threat and attack behaviors, with midazolam effective over a wider range of situations. in contrast, effects on freezing and f ... | 1989 | 2566187 |
| partial coexistence of growth hormone-releasing hormone and tyrosine hydroxylase in paraventricular neurons in rats. | immunocytochemistry revealed growth hormone-releasing hormone (grf)-containing cells (4-10/50 microns thick coronal sections) in the ventral portion of the medial parvicellular subdivision of the paraventricular nucleus (pvn) in the rat. in the same region we also detected about the same number of neurons containing the mrna that encodes grf using in situ hybridization histochemistry. fluorescence double labelling immunohistochemistry showed the presence of grf and tyrosine hydroxylase (th) in t ... | 1989 | 2573894 |
| fever and urticaria in acute giardiasis. | travelers' diarrhea afflicts some 250 million people yearly. a number of etiologic agents have been identified, including bacteria, viruses, and parasites. giardia lamblia is one of the pathogens clearly associated with this syndrome. typical symptoms of giardiasis that include abdominal bloating and cramps are well known, whereas urticaria has rarely been associated with this illness. an american tourist developed acute giardiasis accompanied by urticaria and high fever. no other pathogens were ... | 1989 | 2705846 |
| protective effect of inactivated pasteurella haemolytica bacterin challenged in bovine herpesvirus-1 experimentally infected calves. | formalin-inactivated and sonicated pasteurella haemolytica bacterins were prepared from 1 h cultures of bacterial pellets in rpmi-1640 medium containing 7% fetal calf serum. the bacterial pellets were obtained from logarithmic phase growth of the organism by centrifugation. the protective effect of the vaccine was evaluated in 43 specific-pathogen-free hereford crossbred calves and yearlings in three experiments. cattle were either single vaccinated or boosted via three routes; intratracheally ( ... | 1990 | 2168606 |
| phosphonylmethyl ethers of acyclic nucleoside analogues: inhibitors of hsv-1 induced ribonucleotide reductase. | diphosphates of n-(s)-(3-hydroxy-2-phosphonylmethoxypropyl) and n-(2-phosphonylmethoxyethyl) derivatives of purine and pyrimidine heterocyclic bases inhibit hsv-1 encoded ribonucleotide reductase. of the compounds studied, the most efficient inhibitors of cdp reduction (at 5.1 mumols.l-1) by the hsv-1-encoded enzyme are hpmpapp (ic50 = 0.9 mumols.l-1) and pmeapp (ic50 = 8 mumol.l-1). pmeapp does not inhibit the enzyme isolated from the mutant hsv-1 kos strain pmear which is resistant to pmea at ... | 1990 | 2168691 |
| nitrate reductases of escherichia coli: sequence of the second nitrate reductase and comparison with that encoded by the narghji operon. | the structural genes for nrz, the second nitrate reductase of escherichia coli, have been sequenced. they are organized in a transcription unit, narzywv, encoding four subunits, narz, nary, narw and narv. the transcription unit is homologous (73% identity) to the narghji operon which encodes the genes for nra, the better characterized nitrate reductase of this organism. the level of homology between the corresponding polypeptides ranges from 69% for the narw/narj pair to 86% for the narv/nari pa ... | 1990 | 2233673 |
| [effect of enalapril on heart rate, arterial blood pressure and exocrine pancreatic secretion in the alert dog]. | a changed exocrine pancreatic secretion could be a pathogenetic factor of an acute pancreatitis after administration of angiotensin-converting enzyme (ace) inhibitors. in six conscious dogs with gastric and duodenal thomas fistulas we studied the effect of an intravenous (iv.) bolus injection of 10 mg enalaprilat, an intraduodenal (id.) bolus injection of 20 and 40 mg enalapril (e.), and 0.15 m nacl (20 ml iv., resp., id.) on pancreatic bicarbonate- and protein output in response to secretin (20 ... | 1990 | 2238764 |
| [quantitative characteristics of microcirculation bed in aseptic inflammation of the rat uterus and with the background of the use of carbon-mineral sorbents]. | we studied the volume compactness of the arterial, capillary and venous parts of the microcirculation channel after 24, 48, 72 and 96 hours of the aseptic inflammation and after local application of the carbon-mineral sorbents in the rat's uterus. the local sorption decreased the reaction of the inflammation in the endo- and myometrium. | 1990 | 2279103 |
| estrogen replacement therapy and endometrial carcinoma. | 1990 | 208878 | |
| [postcoital uterine microbe colonization and endometritis in the mare]. | in the mare, natural breeding is associated with bacterial contamination of the reproductive tract. the purpose of this study was to examine postcoital bacterial contamination and the resulting inflammatory response of the uterus. uterine swabs for bacteriological and cytological examination were obtained from 80 mares. each mare was sampled once between 4 and 69 hours postbreeding. in mares which did not conceive, sampling was repeated at the following estrus. the findings were compared with th ... | 1991 | 1948985 |
| horn fly (diptera: muscidae) insecticide resistance in kentucky and arkansas. | the effect of previous insecticide use patterns for horn fly control on the susceptibility spectrum of horn fly (haematobia irritans [l.]) populations from kentucky and arkansas is described. populations of horn flies from both states were tested with three pyrethroids (cyhalothrin, cypermethrin, and permethrin), three organophosphates (diazinon, pirimiphos methyl, and tetrachlorvinphos), and a chlorinated hydrocarbon (methoxychlor). dose-mortality data indicated insecticide resistance in arkans ... | 1991 | 1885841 |
| diabetes-induced rat hyposensitivity to compound 48/80. | rat mortality and contractile responses of isolated tracheas to compound 48/80 from rats made diabetic 4 days before by a single intravenous injection of alloxan and from diabetic rats that had been treated with insulin 6 h before were compared with control animals. diabetic animals and tracheal segments from diabetic rats were significantly less responsive to compound 48/80 than control and insulin-treated diabetic animals. on the other hand, diabetic animals have a lower quantity of peritoneal ... | 1991 | 1913334 |
| inhibin-like "antigonadotropic" activity in the ovine pineal. | in an attempt to define the antigonadotropic activity associated with the protein/peptide extracts of ovine pineals, melatonin- and steroid-free fractions obtained after subjecting crude ovine pineal acetone powder to soft gel chromatography were tested in three bioassay systems: (1) the conventional compensatory ovarian hypertrophy inhibition assay in rats, (2) the coupled bioassay in immature mice that enables one to distinguish factors acting at the level of the pituitary from those acting at ... | 1992 | 1453311 |
| expression and release of neuroregulators during development: monoamines and neuropeptides. | the turnover of catecholamines (ca) was determined in the adrenal medulla and brain of rat fetuses and pups. in general we found a considerable increase soon after birth. the expression of mrna for ca-synthesizing enzymes was also considerably enhanced in the adrenals shortly after birth. furthermore, we demonstrated increased expression of neuropeptides after birth, increased synthesis of mrna encoding for neuropeptide y in the adrenals 24 h after birth; and considerable activation of the subst ... | 1992 | 1306802 |
| [optokinetic nystagmus in neurology]. | 1992 | 205937 | |
| [parenteral nutrition in acute uremia in the surgical patient]. | 1999 | 96386 | |
| [temporary restoration material--scutan]. | 2000 | 110534 | |
| [rotation of an eccentric dipole in a conducting sphere: an analytical model for the vcg (proceedings)]. | 2000 | 92229 | |
| [cardiac arrhythmia]. | 2001 | 93056 | |
| dynamic changes in neuronal volume resulting from osmotic and sodium transport manipulations. | electrophysiologic parameters such as input resistance and response to microperfusion of neurotransmitters vary under circumstances where neurons from isolated ganglia of aplysia californica are subjected to either long-term (several hours) blockade of active sodium transport or to hypo- or hyperosmotic solutions. since one of multiple possible events under these circumstances is neuronal volume changes, we have developed a system using cultured aplysia neurons and confocal scanning laser micros ... | 2004 | 1299127 |
| acute viral respiratory infections in children. | 2004 | 506792 | |
| treatment of dermatomyositis with methotrexate and prednisone. | 2004 | 507874 | |
| physiological response patterns during "intake" and "rejection" tasks. | two 2-min tasks, one requiring outer-directed attention (intake task), the other a mental arithmetic task (rejection task) were presented to 20 subjects. according to lacey the distinguishing feature of the response to intake tasks are cardiac deceleration and blood pressure decreases. none of these responses was obtained. some variables, however, were only affected by one of the tasks; the intake task led to a decreased hand (skin) blood flow and an increased hand vascular resistance, whereas a ... | 2004 | 534671 |
| perceiving the logical status of sentences. | 2004 | 3691021 | |
| electroconvulsive therapy: an overview. | modifications in technique, including the use of anesthesia and muscle-relaxing drugs, make electroconvulsive therapy safe and easy to administer. there are few contraindications, complications are rare, and efficacy is well-documented. | 2004 | 441398 |
| myeloid and erythroid progenitor cells from normal bone marrow adhere to collagen type i. | one of the mechanisms by which normal hematopoietic progenitor cells remain localized within the bone marrow microenvironment is likely to involve adhesion of these cells to extracellular matrix (ecm) proteins. for example, there is evidence that uncommitted, hla-dr-negative progenitor cells and committed erythroid precursors (bfu-e) bind to fibronectin. however, fibronectin is not known to mediate binding of committed myeloid (granulocyte-macrophage) progenitors, raising the possibility that ot ... | 2004 | 1370640 |
| [emergency medical service in greater copenhagen]. | 2004 | 545772 | |
| inducibility of metallothionein biosynthesis in cultured normal and menkes kinky hair disease fibroblasts: effects of copper and cadmium. | metallothionein biosynthesis is not induced by extracellular copper in menkes kinky hair disease (mkhd) or in normal cultured fibroblasts under the conditions of these experiments. in the presence of copper, mkhd fibroblasts also incorporated less cysteine than did normal fibroblasts. extracellular cadmium greatly enhanced the uptake of cysteine in both normal and mkhd cultures. by the technique of polyacrylamide gel electrophoresis, it was demonstrated that metallothionein is induced by cadmium ... | 2004 | 471576 |
| science and technology for health promotion in developing countries: 2. | primary health care is rapidly gaining acceptance as the most practical and rapid solution to the low standards of health care in developing areas. primary health care provides promotive, preventive, curative, and rehabilitative services that are scientifically sound and acceptable within the local culture. this article, which is the second of two, is concerned with defining the major organizational and other problems involved in the delivery of primary health care. maximum community and individ ... | 2004 | 524887 |
| wear of high-density polyethylene on bone and cartilage. | wear of high-density polyethylene on bone and cartilage has resulted in a large volume of plastic particles being shed into the two knees and two hips studied. the giant-cell foreign-body reaction of the synovium may not be sufficient to cope with the amount of debris presented and the destruction of the endosteal bone in one hip, caused by the wear particles and movement of the prosthesis, has made revision impossible. articulation of high-density polyethylene against bone or cartilage either b ... | 2004 | 387800 |
| stimulation of ion release from liposomes by the polyene antibiotic, filipin. | 2005 | 1169041 | |
| chromosomal abnormalities in angio-immunoblastic lymphadenopathy. | chromosomal studies have been performed in 2 patients with angio-immunoblastic lymphadenopathy. in both the cases the presence of abnormal cell lines characterized by marker chromosomes has been detected. application of banding techniques allowed to detect the structural composition of the marker chromosome in 1 of the cases and to show a clonal evolutive pattern of the rearranged chromosomal set; in the same patient a consistent y loss observed in the major fraction of the investigated metaphas ... | 2005 | 1087993 |
| [comparative study on drinking water in japan (akita) and hawaii]. | 2005 | 1169517 | |
| [immunological in vitro tests in the assessment of specific cellular reactivity in tuberculosis]. | 2005 | 1079782 | |
| phloroglucinol derivatives of eleven dryopteris species from japan. | 2005 | 1197418 | |
| micronodular encephalitis and acute leukemia treated with immunosuppressives in a child. | the present paper is the study of a micronodular encephalitis with inclusions occurring in a child suffering from acute leukemia treated with antimitotics and immunosuppressives. the role of the immunosuppressive treatment in the onset of the encephalitic syndrome is discussed. | 2005 | 1242214 |
| [therapeutic effect of complamine in atherosclerosis and ischemic heart disease]. | 2005 | 1273633 | |
| [physiological and hygienic characteristics of the working conditions in laying and insulating operations in the electrical engineering industry]. | 2005 | 1176014 | |
| psychiatric morbidity in a sample of a london coroner's open verdicts. | one hundred and thirty-four deaths recorded as open verdicts in the inner west london coroner's district during 1969 and 1970 have been surveyed for evidence of mental illness. for 110 (82 per cent) of these deaths the probable verdicts were suicide or accident and they were reclassified as undetermined deaths. of these deaths 73 per cent were diagnosed as mentally ill, 54 per cent were receiving medical treatment for psychological symptoms before death, 42 per cent had a history of psychiatric ... | 2005 | 1182365 |
| [symptom of para-esophageal shadow of the tumor in x-ray diagnosis and evaluation of the effectiveness of radiotherapy of esophageal cancer]. | 2005 | 1196036 | |
| xeromammography at a community hospital. a year's experience. | 2005 | 1183210 | |
| thickenings in the coronary arteries in infancy as an indication of genetic factors in coronary heart disease. | in finland, mortality from coronary heart disease is high, and much higher in the eastern than in the western countries. both left and right coronary arteries of 141 children who died under one year of age at the children's hospital, university of helsinki, were investigated. thirty-two of these children formed a western and 41 an eastern group according to the birthplaces of their grandparents in finland. correlations were tested between this geographical distribution and some dimensions of the ... | 2005 | 1112002 |
| [uterine synechias caused by aspiration using a no. 6 curet]. | 2005 | 538828 |