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campylobacter pyloridis: identification and clinical significance. 19873565344
a note on name, viability and urease tests of campylobacter pylori. 19873569261
campylobacter pyloridis and gastritis. 19873569781
antibodies to campylobacter pyloridis in household contacts of infected patients. 19873103831
[isolation of campylobacter pyloridis from gastric mucosa of patients with gastric complaints and susceptibility of the isolates on antibiotics]. 19873119739
campylobacter pylori, gastritis, and peptic ulcer disease in central africa. 19873120933
evaluation of "clo-test" to detect campylobacter pyloridis in gastric mucosa. 19873294906
gastric campylobacter-like organisms, gastritis, and peptic ulcer disease.although the presence of gastric bacteria has been long established, the recognition and isolation of campylobacter pylori and similar organisms has opened a new era in the understanding of inflammatory gastroduodenal conditions. visualization or isolation of gastric campylobacter-like organisms (gclos) is significantly associated with histologic evidence of gastritis, especially of the antrum. correlation with peptic ulceration also exists but probably is due to concurrent antral gastritis. out ...19873297911
[ofloxacin in the therapy of campylobacter pylori-positive duodenal ulcer. a prospective controlled randomized study].50 patients with duodenal ulcer and campylobacter pylori cultured from the antral mucosa were randomly divided into two groups of 25. they received either ranitidine 300 mg at night or the same dose of ranitidine combined with twice daily 200 mg ofloxacin. endoscopic check and biopsy for histological and microbiological tests were performed every two weeks until demonstrable cure of the ulcer. after two weeks the cure rates were 44 and 80%, respectively, after four weeks 68 and 92%, and after si ...19873304929
screening for campylobacter pyloridis in patients with upper dyspepsia and the relation to inflammation of the human gastric antrum.campylobacter pyloridis, a recently detected microorganism, was isolated from gastric antral mucosa in 58% of 119 consecutive patients with upper dyspepsia. there was a highly significant correlation between the presence of campylobacter pyloridis and antral inflammation and a close relation to prepyloric and duodenal ulcer. there was no significant correlation with the severity or type of inflammation. this microorganism, which seems to be as common in denmark as in other parts of the world, is ...19873306892
[an original method of bacteriological sampling for studying campylobacter pylori in duodenal ulcer].the presence of campylobacter pylori in duodenal ulcer was investigated in 26 patients. the method used was a sterile endoscopic sampling technique which forcasted and checked for contamination of the samples. a sterile catheter was introduced through the endoscope and then an infusion of saline was instituted. once the catheter was in the intestinal lumen, the infused solution was aspirated for control of sterility. semi-quantitative cultures of gastric and duodenal juices and of biopsies of th ...19873308614
identification of the outer membrane proteins of campylobacter pyloridis and antigenic cross-reactivity between c. pyloridis and c. jejuni.the outer membrane and surface exposed proteins of four strains of the gastric campylobacter-like organism campylobacter pyloridis were identified by sds-page of sarkosyl-insoluble membranous material and 125i-surface-labelled whole bacteria. although constant outer membrane proteins (molecular mass 61, 54 and 31 kda) were observed in these strains, several variable 125i-labelled surface proteins were detected. c. pyloridis does not appear to express a single surface-exposed major outer membrane ...19873309141
[susceptibility of campylobacter pyloridis to antibiotics].in vitro antibacterial activity of 32 antimicrobials was studied on 20 strains of campylobacter pyloridis (cp). cp is susceptible to beta lactams, cyclins, chloramphenicol, rifampicin, macrolides, aminoglycosides, sometimes to colistin, nalidixic acid, metronidazole, never to vancomycin, trimethoprim, co-trimoxazole.19873309819
campylobacter pyloridis: a new organism to explain an old problem? 19873309916
[campylobacter pylori in duodenal ulcer--a concomitant phenomenon or causal association?].the rediscovery of spiral bacteria in gastric mucosa in recent years has given raise to new speculations concerning the pathogenesis of peptic ulcer disease. due to the features and localisation of this bacterium it was named campylobacter pylori. findings pointing to a pathogenetic role of this bacterium are few and not definitely settled. the frequency of campylobacter on the gastroduodenal mucosa, its short term survival in acidic environment, its extraordinary mobility and content of specifi ...19873310428
campylobacter pyloridis. 19873310489
[campylobacter pyloridis: bacteriological study and sensitivity to antibiotics].twelve strains of campylobacter pyloridis isolated in the antrum and/or fundus in 8 patients were analyzed for antibiotype. the results obtained, compared with those in the literature, enabled assessment of the culture media which are the best adapted for isolation, the main criteria for identification (urease, alkaline phosphatase, nitratereductase, growth temperature), their sensitivities (beta-lactamines, tetracyclines, macrolides) or their resistance to antibiotics (colistin, vancomycin, co- ...19873313211
[campylobacter pylori. current aspect in gastritis and ulcer disease]. 19873315552
campylobacter pylori: new and renewed insights into gastritis-associated ulcer disease (gaud). 19873315920
[role of campylobacter pyloridis in the etiology of gastritis and peptic ulcer]. 19873316831
[campylobacter pylori--microbiological aspects]. 19873318188
[campylobacter pylori colonization of the antrum mucosa in patients with chronic gastritis and peptic ulcer].campylobacter pylori, a bacterium specifically adapted to the environment of gastric mucous is closely associated with peptic gastric diseases. it is detected within the mucus and in relationship to the intercellular spaces in cases of active chronic gastritis. approximately 70% of patients with chronic type-b-gastritis are infected with c. pylori. in type a or reflux gastritis c. pylori is hardly seen. a causal relationship seems likely. more than 80% of patients with duodenal ulcer and round h ...19873318189
[histologic, culture and breath test detection methods and therapy of campylobacter pylori colonization of the stomach]. 19873318190
[serologic diagnosis of campylobacter pylori colonization]. 19873318191
[dose-effect studies with bismuth salts for the elimination of campylobacter pylori]. 19873318192
campylobacter pyloridis: the rediscovery of a forgotten bacterium. 19873321742
[evaluation of per-endoscopic cytology in the identification of campylobacter pylori on gastric mucosa].the presence of campylobacter pylori on gastric mucosa was evaluated by touch cytology of gastric biopsies in a series of 100 patients. results were compared to biopsy cultures. of 43 culture-positive patients, cytology was positive in 37 (86 p. 100). cytology was positive in 16 of 57 culture-negative patients, who had peptic ulcer and/or gastritis on biopsy, conditions widely associated with the presence of campylobacter pylori. cytologic examination, yielding quick results, is thus a sensitive ...19873322923
[campylobacter pyloridis: the etiologic agent of gastritis and peptic ulcer?]. 19873327134
persistence of campylobacter pyloridis despite healing of duodenal ulcer and improvement of accompanying duodenitis and gastritis.campylobacter pyloridis has been associated with antral gastritis and duodenal ulcer. to study the pathogenetic role of these organisms in duodenal ulcer, endoscopic biopsies, two from the first part of duodenum, four from antrum, and four from body and fundus, were taken before and after four weeks of cimetidine treatment (1.2 g/day) from 67 patients with active duodenal ulcer. the biopsies were examined for the presence and severity of any inflammation by two independent pathologists in the ab ...19873665680
[ammonia determination in gastric juice. a new simple rapid test for campylobacter pylori]. 19873665755
lack of invasiveness of campylobacter pylori. 19873665906
establishment of gastric campylobacter pylori infection in the neonatal gnotobiotic piglet.campylobacter pylori, a gram-negative microaerophilic bacterium, has been implicated in the genesis of human gastritis, dyspepsia, and gastroduodenal ulceration. previous attempts to reproduce the diseases in conventional laboratory animal species have been unsuccessful. to determine if neonatal gnotobiotic piglets were susceptible to c. pylori, we orally challenged two litters (n = 17) with 10(9) cfu after pretreating them with cimetidine. controls housed in separate units received nothing or p ...19873666963
[campylobacter pyloridis--a possible etiologic agent in patients with chronic gastritis and peptic ulcer]. 19873669886
non-ulcer dyspepsia and campylobacter pylori gastritis: to treat or not to treat? 19873670207
campylobacter pylori and non-ulcer dyspepsia.non-ulcer dyspepsia (nud) is a poorly understood syndrome often present in association with gastritis. among patients undergoing gastroscopy, some with nud have a gastric mucosa colonized by the campylobacter-like organism, campylobacter pylori. we therefore studied prospectively 55 consecutive patients with nud and 15 normal controls to determine the prevalence of c. pylori organisms, and to investigate their association with histological gastritis, macroscopic evidence of gastritis, sex, smoki ...19873673994
in vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against campylobacter pyloridis (c. pylori).the in vitro interactions between bismuth subcitrate and a variety of antimicrobial agents against 12 campylobacter pyloridis (c. pylori) isolates were studied by the agar dilution checkerboard technique. the combination of bismuth subcitrate with the older quinolone, oxolinic acid, produced synergistic activity against all strains. this observation, however, could not be extended to the (aryl) fluoroquinolones, norfloxacin, ofloxacin, and difloxacin, since synergy was rare or absent when bismut ...19873674850
comparison of biopsy urease test and histologic examination for detection of campylobacter pylori in duodenal, antral and fundic biopsies.the presence of campylobacter pylori was investigated in duodenal, antral and fundic biopsies of 149 consecutive patients undergoing upper gastrointestinal tract endoscopy by biopsy urease tests (clotest; "clo test") and histologic examination ("hist") after modified giemsa staining. positive results were obtained rarely in the duodenum (4.7% and 12.8% by clo test and hist, respectively), but equally frequently in antral (48.3% and 62.4%) and fundic biopsies (55.0% and 54.4%). using combined eva ...19873679081
long term freeze storage of campylobacter pyloridis. 19873680553
comparative sensitivities to antimicrobial agents of campylobacter pylori and the gastric campylobacter like organism from the ferret. 19873680554
campylobacter pylori and antral gastritis in children. 19873683475
[long-term studies of colonization of the gastric mucosa by campylobacter pyloridis].multiple biopsy specimens of gastric mucosa of 15 patients taken at different intervals with an observation period of 4 to 20 years were evaluated. histological examination revealed superficial gastritis in most cases without radical and progressive destruction of the mucosa and in all but one case the presence of clo was demonstrated with varying degree of intensity. no evidence was found for causal relationship between bacterial colonization and inflammation.19873687145
[campylobacter pylori,a commensal, opportunistic or primary pathogenic bacterium. an international discussion by experts on the occasion of the 42d meeting of the german society for digestive and metabolic diseases. salzburg, 9-12 september 1987. proceedings]. 19873687148
[therapy of peptic ulcer and chronic gastritis with bismuth salts].colloidal bismuth subcitrate (cbs) precipitates in an acid environment, adheres to mucus, blocks pepsin activity, retards hydrogen-ion back diffusion and stimulates prostaglandin synthesis. the average healing rate after 4 weeks' treatment with cbs is 78% in duodenal ulcer versus 67% with cimetidine. a direct comparison with ranitidine gives healing rates of 78% (cbs) as opposed to 78% with ranitidine. the corresponding figures in gastric ulcer are 68% (cbs) and 54% (cimetidine). the percentage ...19873687149
[electron microscopic findings during treatment of campylobacter pylori-positive gastritis with bismuth salts]. 19873687150
growth of campylobacter pylori in liquid media.until recently, broth cultivation techniques for campylobacter pylori were unavailable. we developed a method to cultivate bacterial cells within 24 h in liquid media. cultivation in broth depended on the adequate dispersion of appropriate gases. a static broth at 37 degrees c in a gaspak jar (bbl microbiology systems, cockeysville, md.) with a campypak (bbl) envelope did not support growth after 5 days of incubation. a broth placed in a flask on a gyrotory water bath shaker (150 rpm; new brunsw ...19873693542
campylobacter pylori, acid, and bile. 19873693575
response of campylobacter pyloridis to antibiotics, bismuth and an acid-reducing agent in vitro--an ultrastructural study.campylobacter pyloridis was cultured for maximal growth in liquid medium, and effects of exposure to various beta-lactam and macrolide antibiotics, metronidazole, tripotassium dicitrato bismuthane (tdb) and cimetidine were monitored by transmission electronmicroscopy after periods of exposure up to 24 h. with amoxycillin and benzylpenicillin (0.12-1 mg/l) and cephalexin (2 mg/l) the normal bacilliform morphology was replaced by bulging and dumb-bell-like profiles showing cell-wall blebbing and v ...19873694664
[campylobacter pyloridis: opportunist or pathogen in the upper gastrointestinal tract]. 19873604223
[campylobacter pylori--an etiologic agent in gastritis?]. 19873608882
rapid diagnosis of campylobacter pyloridis infection. 19873611402
symptoms improve after the eradication of gastric campylobacter pyloridis. 19873614058
[isolation of campylobacter pyloridis from gastric biopsy material]. 19873614904
campylobacter pyloridis-associated primary gastritis in children.campylobacter pyloridis are spiral-shaped gram-negative bacteria that have recently been associated with gastritis and peptic ulcer diseases in adults. the organisms have been identified in biopsy specimens of the gastric antrum by staining sections with silver stain. to determine the frequency of colonization of the antral mucosa with c pyloridis in association with gastritis in childhood, we retrospectively reviewed 53 cases in patients (mean age 11.9 years) in whom upper endoscopy with antral ...19873615089
[campylobacter pyloridis in the mucosa of gastritis and ulcer patients]. 19873616079
comparative susceptibilities of campylobacter pylori to norfloxacin and other agents.twenty-one strains of campylobacter pylori (campylobacter pyloridis) were tested for susceptibility to norfloxacin and other agents by the serial agar dilution method. ampicillin (mic for 90% of isolates [mic90], 0.016 micrograms/ml) and famotidine (mic90, greater than 1,024 micrograms/ml) were, respectively, the most and the least active of the agents tested. norfloxacin (mic90, 1 microgram/ml) and imipenem (mic90, 0.125 micrograms/ml) were substantially active against this organism.19873619429
[campylobacter pylori in the stomach, duodenum and colon of gastroenterological patients. an epidemiologic study of 120 subjects].in a prospective study of 120 gastroenterological patients in berlin, germany, the prevalence of campylobacter pylori was determined. when the gastric mucosa was normal, the prevalence was one in 19 patients (5.3%). in 101 patients with chronic gastritis it was cultured in 55 (54.5%). in 31 patients with chronic atrophic gastritis the organism was cultured in 25 (81%); in 60 patients with severe gastritis it was present in 75%, in 35 with moderate or severe chronic active gastritis in 82.8%. the ...19873622286
antibacterial action of bismuth in relation to campylobacter pyloridis colonization and gastritis.colloidal bismuth subcitrate (cbs, de-nol) heals duodenal ulcers but with a lower relapse rate than cimetidine, perhaps due to inhibition of campylobacter pyloridis (cp) organisms. to test this hypothesis we studied gastric mucosal histology in three groups of ulcer patients treated with either cimetidine, cbs, or cbs in combination with an antibiotic. cimetidine had no effect on cp or gastric mucosal histology but with cbs therapy there was a significant reduction in the number of bacteria (p l ...19873622946
campylobacter pyloridis, peptic ulcers, and gastritis. 19873629218
[campylobacter pylori, gastritis and peptic ulcer].in the course of routine gastroduodenoscopic examination of 218 patients bioptic mucosal specimens were examined bacteriologically for the presence of campylobacter (c.) pylori. the organism was isolated from 52 out of 53 patients (98%) with duodenal ulcer, 7 out of 9 with gastric ulcer (78%), 24 out of 31 with mucosal erosions (77%), 10 out of 10 with duodenitis (100%), 16 out of 16 with chronic active gastritis (100%) and from 40 out of 73 patients (55%) with inactive chronic gastritis. by con ...19873630180
[campylobacter pyloridis in active chronic gastritis and peptic ulcer].from oct. 1986 to jan. 1987, a total of 74 patients presenting for endoscopy were studied. these included 30 cases of active chronic gastritis and 44 cases of peptic ulcer. biopsy specimens were taken during the endoscopy and sent to the laboratory for campylobacter pyloridis culture within 2 hours. the culture was done by inoculated with chocolate agar, brucella agar and 0.2% urea broth for urease activity. results showed that, 53% (16/32) of active chronic gastritis, 77% (10/13) of gastric ulc ...19873652784
[campylobacter pylori: toward the recognition of a new pathogen?]. 19873653615
[campylobacter pylori and gastric mucosa: histological and bacteriological study and preliminary results of an epidemiological survey in the area of nantes].the aims of this study were to: a) evaluate the prevalence of campylobacter pylori (cp) in patients referred to a gastroenterology unit for upper digestive tract endoscopy, b) compare the results of histologic (warthin-starry method) and bacteriologic (direct and culture) examinations, c) correlate the presence and abundance of cp with the "activity" of chronic gastritis as assessed by antral and fundic specimens, and d) report the preliminary results of an epidemiological survey in the area of ...19873653616
rapid identification of campylobacter pylori (c. pyloridis) by preformed enzymes.campylobacter pylori (c. pyloridis) is a fastidious organism found in the gastric mucosa associated with histological gastritis and peptic ulceration. a rapid identification scheme that detects the presence of preformed enzymes (rosco diagnostica, taastrup, denmark) was applied to clinical isolates of c. pylori. the isolates tested were a very homogeneous group. they all produced oxidase, catalase, urease, alkaline phosphatase, gamma-glutamyl aminopeptidase, leucine aminopeptidase, and dnase. no ...19873654941
campylobacter pyloridis and acid induced gastric metaplasia in the pathogenesis of duodenitis.biopsy specimens of gastric and duodenal mucosa from 290 patients were examined histologically for metaplasia and campylobacter pyloridis. estimates of ph on samples of fasting gastric juice from 55 of the patients were performed, and mucosal biopsy specimens from 33 patients were also cultured for c pyloridis. active duodenitis was seen in 34 duodenal biopsy specimens. thirty (88%) of the patients with active duodenitis had both greater than 5% gastric metaplasia in the duodenal specimen and c ...19873654985
campylobacter pyloridis in patients with gastric carcinoma. 19873657641
[failure of doxycycline in campylobacter pylori-positive gastritis]. 19873803221
enzyme-linked immunosorbent assay for campylobacter pyloridis: correlation with presence of c. pyloridis in the gastric mucosa.antibody to campylobacter pyloridis was measured by elisa in the sera of 160 patients from whom gastric biopsy specimens were also obtained. the antigen was an acid-glycine extract of c. pyloridis, and titers ranged from 80 to 22,000 elisa units (eu). of 117 patients in whom c. pyloridis was detected microbiologically or histologically, 87 (74%) had a titer greater than or equal to 300 eu, and only one had a titer less than 150 eu. of 43 patients in whom c. pyloridis was not detected, only two ( ...19873805774
demonstration of a flagellar antigen shared by a diverse group of spiral-shaped bacteria that colonize intestinal mucus.western blot analysis showed that there is little immunological cross-reactivity of the human pathogens campylobacter jejuni and campylobacter coli with campylobacter pyloridis, except for a very strong cross-reaction between the flagellins. this same antigenic cross-reaction was found with two isolates of gram-negative spiral microaerophilic bacteria that are known to colonize the intestinal mucosa of rodents, but not with the flagellins of a number of other motile bacteria. it is proposed that ...19873818099
ingestion of campylobacter pyloridis causes gastritis and raised fasting gastric ph.campylobacter pyloridis was ingested by a volunteer who had a histologically normal gastric mucosa and fasting gastric ph recordings of less than 2. three days later he developed moderate to severe attacks of epigastric pain. on the 5th day after ingestion c. pyloridis was cultured from antral biopsies which showed histological acute gastritis. however, fundal histology and fasting gastric ph were normal. on the 8th day fasting gastric ph rose to 7.6. on day 11 c. pyloridis was cultured from bot ...19873826027
[campylobacter pylori--is there a connection with peptic ulcer?].in 67 patients, mucosal biopsies were taken in gastroduodenoscopy and culture set up to demonstrate campylobacter pylori. campylobacter pylori was cultured from 91% of the patients with peptic ulcer, in 76% of patients with gastritis and in 28% of patients without histological detection of gastritis. electron microscopic investigations of duodenal mucosa showed that this bacterium attaches to the metaplastic cells of the antral type. this cell type is regularly encountered in the duodenal mucosa ...19873829927
[campylobacter pylori]. 19873149939
[campylobacter pylori and gastroduodenal pathology]. 19873149940
[campylobacter pylori: a retrospective study of 150 gastric biopsies with chronic type b gastritis]. 19873149942
[gastroduodenal ulcer and campylobacter pylori. behavior under treatment with de-nol or metronidazole]. 19873149943
[campylobacter pylori gastritis. comparison of various diagnostic methods]. 19873332530
treatment failure of ofloxacin in campylobacter pylori infection. 19872883434
serological screening for campylobacter pylori in candidates for renal transplantation. 19872883460
campylobacter pylori detected noninvasively by the 13c-urea breath test.the high endogenous urease activity of campylobacter pylori was exploited in a non-invasive test for the presence of this organism in the stomach. when 13c-urea was administered orally after a test meal, urea-derived 13co2 appeared in the respiratory co2 of infected individuals at a constant rate for greater than 100 min. the test was validated in 26 individuals who underwent both the 13c-urea breath test and endoscopic biopsy of the antral mucosa for culture and histological examination. each p ...19872883491
14c-urea breath analysis, a non-invasive test for campylobacter pylori in the stomach. 19872884468
campylobacter pylori infection in homosexuals. 19872885612
campylobacter pylori and peptic ulcer. 19872886854
campylobacter pylori and peptic ulcer disease. 19872887926
person-to-person transmission of campylobacter pylori. 19872887955
antibody to campylobacter pylori in families of index children with gastrointestinal illness due to c pylori. 19872887956
campylobacter pylori and gastric manipulation for morbid obesity. 19872889113
campylobacter pylori and recurrence of duodenal ulcers--a 12-month follow-up study.in 39 patients with endoscopically healed duodenal ulcers repeat endoscopy and two antral biopsies after 1 year showed a relapse rate of 59%. only post-treatment campylobacter pylori status was a significant predictor of endoscopic relapse. 79% of patients who remained culture positive had a relapse, compared with 27% of culture-negative patients. relapse was more likely (66%) in patients with a recurrence of c pylori after apparent eradication of the organism than in those who remained negative ...19872890019
naturally occurring gastritis associated with campylobacter pylori infection in the rhesus monkey. 19872890941
isolation and characterization of campylobacter pyloridis from gastric biopsies.gastric biopsy specimens were examined microbiologically and histologically for the presence of campylobacter pyloridis. of 51 randomly selected patients, 22 (43%) were found to harbor c. pyloridis in the gastric mucosa. the histologic demonstration of spiral organisms observed by staining with hematoxylin and eosin correlated well with microbiologic isolation of the organisms. there was a strong association (95.5%) between c. pyloridis in the gastric mucosa and histologically defined gastritis. ...19872432774
campylobacter pyloridis gastritis i: detection of urease as a marker of bacterial colonization and gastritis.a method to detect the presence of campylobacter pyloridis in dyspeptic patients is described. the test procedure involves placing a gastric pinch biopsy into a small amount of a solution containing urea and a ph indicator in the well of a microtiter tray. the method depends on the ability of c. pyloridis to hydrolyse urea and release an alkaline product (ammonia). the "microtiter biopsy urease test" is 100% specific for c. pyloridis and has a 91% sensitivity after 18 h reaction time. seventy-fi ...19872436470
campylobacter pyloridis gastritis ii: distribution of bacteria and associated inflammation in the gastroduodenal environment.the distribution of campylobacter pyloridis in the stomach and duodenal bulb of two series of patients (n = 53) with dyspeptic symptoms was studied. in all patients where a comprehensive search of the stomach was conducted, c. pyloridis and active chronic gastritis were associated. that is, the presence of this organism anywhere in the stomach may be taken as a marker of active chronic gastritis within that stomach, although not necessarily at the site of bacterial detection. two main patterns o ...19872436471
simple half-gram stain for showing presence of campylobacter pyloridis in sections. 19872440912
rapid staining of campylobacter pyloridis. 19872447004
is it really more difficult to treat prepyloric ulcers?prepyloric and duodenal ulcers have some common characteristics: gastric acid secretion is increased and there is an association with blood group o. many, therefore, have considered prepyloric ulcers to be a variety of duodenal ulcer disease. from an anatomical point of view, however, prepyloric ulcers are clearly gastric ulcers. after proximal selective vagotomy, the recurrence rate is very high, amounting to more than 30% in 5 years; this is significantly higher than the rate for duodenal ulce ...19872979694
what is new in the epidemiology and pathogenesis of peptic ulcer?the old dictum 'no acid--no ulcer' is no longer a sufficient explanation of the pathogenesis of ulcer disease. the real question is 'if acid--why ulcer?' although acid remains predominant, some of the other factors influencing ulcerogenesis are nocturnal acid secretion, pepsin enzyme subspecies, the mucus layer, bicarbonate levels, prostaglandins, campylobacter pylori infection, consumption of non-steroidal anti-inflammatory drugs, and smoking habits. although the ulcer burden has been greatly r ...19872979699
significance of campylobacter pylori.there is an explosion of interest in the role of campylobacter pylori as a cause of active chronic gastritis. this curved spiraled microorganism can readily be detected within the mucus gel covering the stomach mucosa, especially in patients suffering from peptic ulcer disease or non-ulcer dyspepsia. to what extent this intriguing microorganism is causally related to peptic ulcer disease remains to be elucidated, but all the evidence which is available so far supports a pathogenetically importan ...19872979701
[comparison of methods for the identification of campylobacter pylori in gastric biopsies of patients with dyspepsia].campylobacter pylori has been associated with gastro-duodenal inflammatory disease. ninety-five adults with dyspepsia were examined for the presence of c. pylori in the gastric antrum and near gastric or duodenal ulcers (when present) by means of culture, gram and acridine orange stains, and urease activity of biopsies. c. pylori was identified from 51 out of 67 patients with chronic gastritis, from 9 out of 9 patients with duodenal ulcer, and from 8 out of 10 patients with gastric ulcer. acridi ...19872459724
[campylobacter pylori and its role in the etiopathogenesis of gastroduodenal ulcer]. 19873078194
evaluation of staining methods for identifying campylobacter pylori.campylobacter pylori has been implicated in the pathogenesis of peptide ulcer disease. the rapid identification of this organism may depend upon histologic diagnosis, because culture methods are complex and require a minimum of seven days in order to identify a negative specimen. the purpose of this study was to determine which stain used to identify this organism was the most cost-effective and easiest to perform and interpret on a routine basis. sixty-one consecutive gastric antral biopsies we ...19882459956
rapid diagnosis of campylobacter pylori by gram's stain.campylobacter pylori (cp) is implicated as a probable pathogen in gastritis and peptic ulcer disease. a blinded prospective study of 112 subjects evaluated how gram's-stained touch preparations of mucosal biopsies compared with culture, routinely processed hematoxylin and eosin (h and e) and warthin-starry (ws) staining in confirming the presence of cp. at endoscopic examination, two mucosal biopsies were taken from the gastric antrum and two from the fundus of each subject. one biopsy from each ...19882459961
problems with clinical trials on campylobacter pylori.clinical trials investigating campylobacter pylori infection have proven difficult to conduct and to interpret. those trials examining the relapse rates of duodenal ulcer disease among subjects in whom c. pylori infection has been eradicated have shown a significant reduction in recurrence rates. however, since the bismuthate compounds used in these trials have cytoprotective ulcer-healing properties, reduced relapse rates cannot be attributed to antibiotic activity alone. those trials examining ...19882980756
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