Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| enhancers and attenuators of risk associations of chronic hepatitis b virus infection with hepatocellular carcinoma in type 2 diabetes. | chronic hepatitis b virus (hbv) infection promotes hepatocellular carcinoma (hcc) risk. in type 2 diabetes (t2d), use of insulin and statins was associated with reduced cancer risk while co-presence of low ldl cholesterol (ldlc <2.8 mmol/l) plus low triglyceride (tg; <1.7 mmol/l) increased cancer risk. there is experimental evidence showing that insulin insufficiency might promote hcc. in this study, we examined whether this lipid subphenotype and use of insulin or statins might modify the promo ... | 2013 | 23250907 |
| relationship between age and prevalence of hepatitis b infection in first-year university students in hong kong. | to determine the effect of age on the prevalence of hepatitis b virus (hbv) infection during a routine screening programme of first-year students enrolled in health sciences studies at the chinese university of hong kong from 2001 to 2009. | 2013 | 23233215 |
| uncommon cause of severe pneumonia: co-infection of influenza b and streptococcus. | influenza and pneumococcus co-infection can cause severe morbidity and mortality. usually, this entails influenza a, while infection by influenza b is rarely serious. the literature describes influenza a epidemics leading to prolific loss of lives, notably the 1918 epidemic was blamed for the deaths of 40 to 50 million people. in this report, four patients were infected by influenza b during the influenza epidemic of 2011/12 in hong kong. all of them were previously healthy and had no chronic di ... | 2013 | 24310663 |
| enhanced detection of hepatitis b virus in hong kong blood donors after introduction of a more sensitive transcription-mediated amplification assay. | a total of 517,072 and 399,326 consecutive donations were screened for hepatitis b virus (hbv) by individual-donation nucleic acid testing (id-nat) using ultrio and ultrio plus assays (novartis diagnostics), respectively. the impact of more sensitive hbv detection by the latter assay version was established by comparing nat yield and transmission risk. | 2013 | 23521050 |
| age-specific prevalence of hepatitis b virus infection in young pregnant women, hong kong special administrative region of china. | to investigate the age-specific prevalence of hepatitis b virus (hbv) infection in young pregnant women in hong kong special administrative region (sar), china, and to determine whether an increase in prevalence occurs during adolescence. | 2014 | 25378739 |
| hepatocellular carcinoma after kidney transplantation: analysis of hong kong renal registry. | kidney transplant recipients have increased risk of cancers when compared with the general population. hepatocellular carcinoma (hcc) is extremely important in asia where hepatitis b virus (hbv) infection is endemic. the aim is to study the epidemiological and clinical aspects of all de novo hcc in our kidney transplant recipients. moreover, various preventive strategies which may help to optimize the outcome will also be discussed. a retrospective review of all patients who developed hcc after ... | 2014 | 24655030 |
| comparison of acute hepatitis e infection outcome in patients with and without chronic hepatitis b infection: a 10 year retrospective study in three regional hospitals in hong kong. | acute hepatitis e virus (hev) infection has recently become the commonest cause of acute viral hepatitis in hong kong (hk) with majority of hev belonging to genotype 4. studies from china have shown that acute hepatitis e patients with underlying chronic hepatitis b virus (hbv) infection may have a worse outcome than those without. in india where genotype 1 is more prevalent, superinfection with hepatitis e on patients with chronic liver disease including chronic hepatitis b infection can cause ... | 2014 | 24646686 |
| low-volume deceased donor liver transplantation alongside a strong living donor liver transplantation service. | at our center, living donor liver transplantation (ldlt) is the main workload supported by a strong, mature service. deceased donor liver transplantation (ddlt) is performed but in small volume. this study aimed to review the results of a low-volume ddlt service alongside a strong ldlt service. | 2014 | 24385193 |
| hong kong liver cancer staging system is associated with better performance for hepatocellular carcinoma: special emphasis on viral etiology. | hong kong liver cancer (hklc) staging system was developed for prognostic and treatment evaluation for hepatocellular carcinoma (hcc) but is not externally validated. we aimed to evaluate and compare hklc system with barcelona clínic liver cancer (bclc) staging system. the prognostic performance, discriminatory ability, and efficacy of treatment recommendations were compared between the bclc and hklc systems. significant differences in survival were found across all stages of bclc and across sta ... | 2015 | 26469917 |
| rubella seronegativity in antenatal screening - is it influenced by the introduction of universal childhood rubella immunization? | this study examined the impact of rubella immunization, implemented in hong kong in phases since 1978, on antenatal rubella serological status in chinese women. | 2015 | 26271826 |
| comparative epidemiology of influenza b yamagata- and victoria-lineage viruses in households. | influenza b viruses split into 2 distinct lineages in the early 1980s, commonly named the victoria and yamagata lineages. there are few data on the comparative epidemiology of victoria- and yamagata-lineage viruses. in 2007-2011, we enrolled 75 and 34 households containing index patients with acute respiratory illness who tested positive for yamagata- and victoria-lineage viruses, respectively, from outpatient clinics in hong kong, china. these index patients and their household contacts were fo ... | 2015 | 26400854 |
| the dynamic relationship between clinical symptomatology and viral shedding in naturally acquired seasonal and pandemic influenza virus infections. | although the pattern of viral shedding over time has been documented in volunteer challenge studies, understanding of the relationship between clinical symptomatology and viral shedding in naturally acquired influenza infections in humans remains limited. | 2016 | 26518469 |
| prevalence of hepatitis b and clinical outcomes in inflammatory bowel disease patients in a viral-endemic region. | little is known of the prevalence of hepatitis b virus (hbv) infection and its effect on choice of therapy and disease course in patients with inflammatory bowel disease (ibd). we assessed the prevalence of hbv in hong kong as well as determinants of altered transaminases, effects of hbv infection on therapeutic strategy and clinical course in ibd. | 2016 | 27549153 |
| immune persistence after hepatitis b vaccination in infancy - fact or fancy? | the hepatitis b vaccine has been introduced for more than 3 decades. in hong kong, excellent vaccine coverage through an efficient public health care system, together with supplemental programmes and easy availability of the vaccine, meant that most young pregnant women, and university students at entrance, should have been protected. yet significant correlations in the prevalence of hbv infection with age were found in these groups of subjects, increasing from low to high endemicity rates from ... | 2016 | 26810256 |
| incorporating serum level of hepatitis b surface antigen or omitting level of hepatitis b virus dna does not affect calculation of risk for hepatocellular carcinoma in patients without cirrhosis. | tests for hepatitis b virus (hbv) dna are expensive, and levels of hepatitis b surface antigen (hbsag) can help determine the risk for hepatocellular carcinoma (hcc) in patients with chronic hbv infection. we investigated how adding data to knowing the level of hbsag or excluding measurement of hbv dna affected the accuracy of the risk estimation for hepatocellular carcinoma in chronic hepatitis b (reach-b) scoring system in determining the risk for hcc. | 2016 | 26598229 |
| equine rhinitis b viruses in horse fecal samples from the middle east. | among all known picornaviruses, only two species, equine rhinitis a virus and equine rhinitis b virus (erbv) are known to infect horses, causing respiratory infections. no reports have described the detection of erbv in fecal samples of horses and no complete genome sequences of erbv3 are available. | 2016 | 27267372 |
| serum 25-hydroxyvitamin d was not associated with influenza virus infection in children and adults in hong kong, 2009-2010. | some studies have hypothesized that vitamin d may have a role to play in protection against influenza virus infections and illnesses, and that seasonal fluctuation in serum 25-hydroxyvitamin d [25(oh)d] may affect seasonal patterns of influenza virus infections. | 2016 | 27798334 |
| pregnancy and maternal chronic hepatitis b infection-evidence of reproductive advantage? | as multiparas have high prevalence of chronic hepatitis b virus (hbv) infection, we examined here the relationship between the number of pregnancies with hbv infection. | 2017 | 28370686 |
| surveillance and response of hepatitis b virus in hong kong special administrative region, 1988-2014. | 2017 | 27757251 | |
| population-based hospitalization burden of lineage specific influenza b children in hong kong, 2004-2014. | influenza b virus has been perceived to cause less disease burden and milder disease when compared to influenza a, but recent studies suggest influenza b does have a significant impact. we aimed to estimate the burden of influenza b virus infections on hospitalizations in hong kong, in the context of virus lineage changes over time. | 2017 | 28387792 |
| long-term outcomes of entecavir monotherapy for chronic hepatitis b after liver transplantation: results up to 8 years. | long-term antiviral prophylaxis is required to prevent hepatitis b recurrence for patients with chronic hepatitis b after liver transplantation. we determined the long-term outcome of 265 consecutive chronic hepatitis b liver transplant recipients treated with entecavir monotherapy without hepatitis b immune globulin. viral serology, viral load, and liver biochemistry were performed at regular intervals during follow-up. the median duration of follow-up was 59 months. the cumulative rates of hep ... | 2017 | 28370215 |
| impact of diabetes mellitus and hepatitis b virus coinfection on patients with chronic hepatitis c: a territory-wide cohort study. | studies have demonstrated a higher prevalence of diabetes mellitus (dm) in patients with chronic hepatitis c (chc). furthermore, coinfection with hepatitis b virus (hbv) is common because of its endemicity in asian-pacific regions. the aim of the present study was to investigate the impact of dm and hbv coinfection on the clinical outcomes in chinese chc patients. | 2018 | 28949045 |