Publications

a novel bat coronavirus closely related to sars-cov-2 contains natural insertions at the s1/s2 cleavage site of the spike protein.	the unprecedented pandemic of pneumonia caused by a novel coronavirus, sars-cov-2, in china and beyond has had major public health impacts on a global scale [1, 2]. although bats are regarded as the most likely natural hosts for sars-cov-2 [3], the origins of the virus remain unclear. here, we report a novel bat-derived coronavirus, denoted rmyn02, identified from a metagenomic analysis of samples from 227 bats collected from yunnan province in china between may and october 2019. notably, rmyn02 ...	2020	32416074
emergence of novel coronavirus and progress toward treatment and vaccine.	in late december 2019, a group of patients was observed with pneumonia-like symptoms that were linked with a wet market in wuhan, china. the patients were found to have a novel coronavirus genetically related to a bat coronavirus that was termed sars-cov-2. the virus gradually spread worldwide and was declared a pandemic by who. scientists have started trials on potential preventive and treatment options. currently, there is no specific approved treatment for sars-cov-2, and various clinical tri ...	2020	32495979
genomic variance of the 2019-ncov coronavirus.	there is a rising global concern for the recently emerged novel coronavirus (2019-ncov). full genomic sequences have been released by the worldwide scientific community in the last few weeks to understand the evolutionary origin and molecular characteristics of this virus. taking advantage of all the genomic information currently available, we constructed a phylogenetic tree including also representatives of other coronaviridae, such as bat coronavirus (bcov) and severe acute respiratory syndrom ...	2020	32027036
a palindromic rna sequence as a common breakpoint contributor to copy-choice recombination in sars-cov-2.	much remains unknown concerning the origin of the novel pandemic coronavirus that has raged across the globe since emerging in wuhan of hubei province, near the center of the people's republic of china, in december of 2019. all current members of the family coronaviridae have arisen by a combination of incremental adaptive mutations, against the backdrop of many recombinational events throughout the past, rendering each a unique mosaic of rna sequences from diverse sources. the consensus among v ...	2020	32737584
proteolytic cleavage of the sars-cov-2 spike protein and the role of the novel s1/s2 site.	severe acute respiratory syndrome coronavirus 2 (sars-cov-2), the causative agent of coronavirus disease 19 (covid-19) has rapidly spread from an initial outbreak in wuhan, china in december 2019 to the rest of the world within a few months. on march 11th 2020, the rapidly evolving covid-19 situation was characterized as a pandemic by the who. much attention has been drawn to the origin of sars-cov-2, a virus which is related to the lineage b betacoronavirus sars-cov and sars-related coronavirus ...	2020	32714113