Publications

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mycobacterium tuberculosis resistance to antituberculosis drugs in mozambique.to determine the drug resistance profile of mycobacterium tuberculosis in mozambique.201724831398
ultrasound-guided intrapleural positioning of pleural catheters: influence on immediate lung expansion and pleurodesis in patients with recurrent malignant pleural effusion.to evaluate the role of intrapleural positioning of a pleural catheter in early lung expansion and pleurodesis success in patients with recurrent malignant pleural effusion (rmpe).201728746529
noisy ocular recognition based on three convolutional neural networks.in recent years, the iris recognition system has been gaining increasing acceptance for applications such as access control and smartphone security. when the images of the iris are obtained under unconstrained conditions, an issue of undermined quality is caused by optical and motion blur, off-angle view (the user's eyes looking somewhere else, not into the front of the camera), specular reflection (sr) and other factors. such noisy iris images increase intra-individual variations and, as a resu ...201729258217
implications of alteration processes on radon emanation, radon production rate and w-sn exploration in the panasqueira ore district.alteration processes have strong impacts on the chemical and physical properties of rock masses. because they can affect the contents and the distribution of u as well as enhance the permeability of the bedrock, they may lead to a significant increase of radon release to the environment. however, their influence on radon emanation and radon production rate has yet to be properly assessed. to investigate the impact of alteration processes on the radiological properties, samples were collected in ...201729223909
bisexual and bidirectional: assessing the potential for hiv bridging in mozambique.african men who have sex with men (msm) frequently, and often concurrently, have female partners, raising concerns about hiv sexual bridging. we explored potential hiv transmission in mozambique from and to female partners of msm focusing on preferred anal sex role and circumcision status. data collected in a respondent-driven sampling study of msm in 2011 in maputo and beira. men who had oral or anal sex with other men 12 months prior completed a questionnaire and consented for hiv testing. sta ...201729188391
prevalence of diabetes mellitus in newly diagnosed pulmonary tuberculosis in beira, mozambique.data regarding the association between diabetes mellitus (dm) and tuberculosis (tb) in africa are scarce. dm screening among tb patients in mozambique was carried out.201729085405
multi-site cholera surveillance within the african cholera surveillance network shows endemicity in mozambique, 2011-2015.mozambique suffers recurrent annual cholera outbreaks especially during the rainy season between october to march. the african cholera surveillance network (africhol) was implemented in mozambique in 2011 to generate accurate detailed surveillance data to support appropriate interventions for cholera control and prevention in the country.201728991895
simulation in medical school education.the universidade da beira interior (ubi), covilhã, portugal in the medical degree course uses simulation in an integrated and comprehensive program as a pedagogical tool.201728873924
socio-demographic, marital, and psychosocial factors associated with condom use negotiation self-efficacy among mozambican women at risk for hiv infection.in mozambique, women are the most affected by hiv/aids. self-efficacy is one of the main predictors of effective use of a condom. therefore, it is essential to identify the factors that influence condom-use negotiation self-efficacy in vulnerable women. the aim of this paper is to identify socio-demographic, marital, and psychosocial factors associated with condom-use negotiation self-efficacy among mozambican women at risk for hiv infection.201728831688
simple motor tasks independently predict extubation failure in critically ill neurological patients.to evaluate the usefulness of simple motor tasks such as hand grasping and tongue protrusion as predictors of extubation failure in critically ill neurological patients.201728746528
developing nurse medication safety training in a health partnership in mozambique using behavioural science.globally, safe and effective medication administration relies on nurses being able to apply strong drug calculation skills in their real-life practice, in the face of stressors and distractions. these may be especially prevalent for nurses in low-income countries such as mozambique and continuing professional development post-registration may be important. this study aimed to 1) explore the initial impact of an international health partnership's work to develop a drug calculation workshop for nu ...201728676121
iodine deficiency a persisting problem: assessment of iodine nutrition and evaluation of thyroid nodular pathology in portugal.the goal of eliminating iodine deficiency (id) by the year 2000 has still not been achieved in several countries. more than 2 billion people worldwide (over 260 million school age children) remain id. in europe, there are still countries, such as portugal, without national general population data on iodine nutrition (in). this study aims at evaluating combined complementary data of the in of the general population through urinary iodine concentration (uic) and the thyroid histology profile from ...201727619914
the castanea sativa bur as a new potential ingredient for nutraceutical and cosmetic outcomes: preliminary studies.chestnuts are a common food product in mediterranean countries, being recognized also for their beneficial effects on human health. nevertheless, during processing, these fruits generate a large amount of food by-products, such as shells and burs. in the present work, the macronutrient composition, vitamin e profile and amino acid content of the burs were determined in samples from three different portuguese regions (minho, trás-os-montes and beira-alta). the nutritional composition was similar ...201727990543
physicochemical fingerprinting of thermal waters of beira interior region of portugal.mineral natural waters and spas have been used for therapeutic purposes for centuries, with portugal being a very rich country in thermal waters and spas that are mainly distributed by northern and central regions where beira interior region is located. the use of thermal waters for therapeutic purposes has always been aroused a continuous interest, being dependent on physicochemical fingerprinting of this type of waters the indication for a treatment in a specific pathological condition. in the ...201727142760
neonatal tactile stimulation at birth in a low-resource setting.stimulation is the most common intervention during neonatal resuscitation at birth, but scarce information is available on the actual methods, timing and efficacy of this basic step. to evaluate the occurrence, patterns and response to tactile stimulation at birth in a low-resource setting.201830236090
prevalence and predictors of malaria in human immunodeficiency virus infected patients in beira, mozambique.co-infection between malaria and hiv has major public health implications. the aims of this study were to assess the malaria prevalence and to identify predictors of positivity to malaria test in hiv positive patients admitted to the health center são lucas of beira, mozambique. a retrospective cross-sectional study was performed from january 2016 to december 2016. overall, 701 adult hiv patients were enrolled, positivity to malaria test was found in 232 (33.0%). these patients were found to be ...201830227677
deprescribing in primary care in portugal (depil17-20): a three-phase observational and experimental study protocol.polypharmacy is commonly defined as the simultaneous taking of five or more drugs. deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. the direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually ...201830018092
effect of a low-dose/high-frequency training on real-life neonatal resuscitation in a low-resource setting.as intrapartum-related events represent a quarter of all neonatal deaths, education on neonatal resuscitation is a critical priority.201830011393
reaching 100 in the countryside: health profile and living circumstances of portuguese centenarians from the beira interior region.the interest in studying a specific population of centenarians who lives in the country's interior region (pt100-bi) emerged during the first portuguese systematic study about centenarians (pt100 oporto centenarian study). this region of portugal is predominantly rural and is one of the regions with the largest number of aged people. the aim of this study is to provide information on the centenarians who live in the beira interior region, specifically in terms of their health status and the heal ...201830008746
the at risk child clinic (arcc): 3 years of health activities in support of the most vulnerable children in beira, mozambique.the concept of “children at risk” changes worldwide according to each specific context. africa has a large burden of overall risk factors related to childhood health and development, most of which are of an infective or social origin. the aim of this study was to report and analyze the volumes of activities of fifteen at risk child clinics (arccs) within the beira district (mozambique) over a 3 year-period in order to define the health profile of children accessing such health servic ...201829954117
pathways of care for hiv infected children in beira, mozambique: pre-post intervention study to assess impact of task shifting.in 2013, mozambique implemented task-shifting (ts) from clinical officers to maternal and child nurses to improve care for hiv positive children < 5 years old. a retrospective, pre-post intervention study was designed to evaluate effectiveness of a new pathway of care in a sample of beira district local health facilities (lhfs), the primary, local, community healthcare services.201829879951
teenage pregnancies in mozambique: the experience of "servicios amigos dos adolescentes" clinics in beira.the purpose of this article is to provide insights into the demand for pregnancy-related health services by adolescent girls and young women in mozambique. we analysed the patient registers for the first year of operation (2014) of the servicios amigos dos adolescentes (saaj) [friendly services for adolescents] clinics in beira, mozambique. these registers provide details of the service demands of, and services provided to the 8 290 adolescent girls and young women who accessed the 6 saaj clinic ...201829504502
predictors of therapy failure in newly diagnosed pulmonary tuberculosis cases in beira, mozambique.tuberculosis (tb) remains a major global health issue, ranking in the top ten causes of death worldwide. a deep understanding of factors influencing poor treatment outcomes may allow the development of additional treatment strategies, focused on the most vulnerable groups. aims of the study were: (i) to evaluate the treatment outcome among tb subjects followed in an outpatient setting and (ii) to analyze factors associated with treatment failure in newly diagnosed patients with pulmonary tb in b ...201829402317
mycobacterium tuberculosis spoligotypes and drug-resistant characterization from beira compared to genotypes circulating in mozambique.mozambique is one of three countries with high prevalence of tuberculosis (tb), tb/human immunodeficiency virus coinfection, and multidrug-resistant tb. we aimed to describe mycobacterium tuberculosis spoligotypes circulating among drug resistant (dr) strains from beira, mozambique comparing them with genotypes in the country.201931778400
nutritional services for children in beira, mozambique: a study reporting on participatory use of data to generate quality improvement recommendations.existing literature suggest frequent gaps in the quality of care (qoc) provided to children with malnutrition in low-income and middle-income countries. beira is the second largest city in mozambique. this study included two phases: phase 1 was a systematic assessment of the qoc provided to malnourished children in beira; phase 2 aimed at using findings of the assessment to develop recommendations, with a participatory approach, to improve qoc.201931750405
macrofungi of mata da margaraça (portugal), a relic from the tertiary age.mata nacional da margaraça represents a rare example where the atlantic climate influences the perpetuity of a small enclave of a previously widespread laurel forest. the higher relative humidity values (> 80%), which are almost constant all year long and the mild temperatures, rarely exceeding 30°c, even in the dry season (june to september), create an insular-like effect. the biological communities of margaraça exhibit a transitory character. the forest is dominated by quercus robur and castan ...201931619938
incorporation of cró thermal water in a dermocosmetic formulation: cytotoxicity effects, characterization and stability studies and efficacy evaluation.development of cosmetic formulations to provide a controlled release of hydrophilic active compounds from mineral medicinal waters constitutes an attractive challenge. the objective of this study was the development and the characterization of a dermocosmetic gel formulation with cró thermal water, from beira interior of portugal, as a major functional ingredient.201931529705
epidemiological profile of health consultations during the mozambique 9th national cultural festival, august 2016.the use of mass gatherings as spaces to practice health surveillance has been growing in recent years. in mozambique, the 9th national festival of culture in 2016 was selected for this practice. a specific public health surveillance system to facilitate rapid detection of outbreaks and other health-related events was implemented for this event with real time data collection and analysis.201931448015
outbreak of cholera due to cyclone kenneth in northern mozambique, 2019.cyclone kenneth was the strongest in the recorded history of the african continent. it landed in the cabo delgado province in northern mozambique on 25 april 2019, causing 45 deaths, destroying approximately 40,000 houses, and leaving 374,000 people in need for assistance, most at risk of acquiring waterborne diseases such as cholera. this short article aims to explain how the resulting cholera outbreak occurred and the response by the government and partner organizations. the outbreak was decla ...201931443180
uncommon testicular localization of disseminated tb: a case report from mozambique.tuberculosis (tb) of the testicle is a rarely reported and poorly described disease localization. there are no well-defined clinical features suggestive of testicular tb, which makes the diagnosis difficult to establish, especially in low-income settings like mozambique, where tb is endemic and often associated with hiv-infection; both considered leading causes of death worldwide. we reported the case of a 45-year-old male, hiv positive, naïve to antiretroviral treatment, admitted to the departm ...201931305938
differential patterns of disease and injury in mozambique: new perspectives from a pragmatic, multicenter, surveillance study of 7809 emergency presentations.there is a paucity of primary data to understand the overall pattern of disease and injuries as well as related health-service utilization in resource-poor countries in africa.201931291292
pattern of domestic violence from 2011 to 2015 in beira, mozambique.violence against women represents a violation of a fundamental human right and is a significant cause of death and disability worldwide. in developing countries, this issue is particularly dramatic and in sub-saharan africa were reached 65% of women reporting domestic violence.201931148977
inhaler technique education in elderly patients with asthma or copd: impact on disease exacerbations-a protocol for a single-blinded randomised controlled trial.chronic obstructive pulmonary disease (copd)and asthma affect more than 10% of the population. most patients use their inhaler incorrectly, mainly the elderly, thereby becoming more susceptible to poor clinical control and exacerbations. placebo device training is regarded as one of the best teaching methods, but there is scarce evidence to support it as the most effective one to improve major clinical outcomes. our objective is to perform a single-blinded rct to assess the impact of this educat ...201930696670
time delay and associated mortality from negative smear to positive xpert mtb/rif test among tb/hiv patients: a retrospective study.the genexpert mtb/rif assay (xpert®) is known to be a feasible, effective and a hopeful tool for rapid tuberculosis (tb) diagnosis and treatment. however, little is known about the time delay caused by initial negative sputum smear microscopy (nssm), but consecutive positive xpert tb test (pxtbt) and its association with tb mortality in resource-constrained settings. we aimed to estimate the median time delay between initial nssm but consecutive pxtbt and tb treatment initiation and its associat ...201930616533
unseen, unheard and unprotected: prevalence and correlates of violence among female sex workers in mozambique.violence against women, including female sex workers, is a public health concern worldwide. this is the first study in mozambique to estimate the prevalence of and factors associated with physical and sexual violence against female sex workers. we used data collected from 1,250 women recruited using respondent-driven sampling in the cities of maputo, beira and nampula in 2011-12. participants were 15 years of age and reported having had sex for money in the preceding six months. prevalence of ph ...201930451098
decision making and situational awareness in neonatal resuscitation in low resource settings.data on non-technical skills (i.e. task management, team working, situation awareness and decision-making) of healthcare providers during real-life newborn resuscitation in low-resource settings are lacking. we aimed to assess non-technical skills of trained midwives during real-life newborn resuscitation in a low-resource setting before and after participation in a modified nrp course, and after a low-dose/high-frequency training.201930391367
noninvasive measurements of ovarian activity in beira antelope (dorcatragus megalotis).as the natural habitat of more and more species becomes depleted, captive breeding programmes have become established to bring species back from the brink of extinction. monitoring the reproductive status of an individual is essential in order to improve breeding success. traditional methods have involved stressful blood sampling, and thus noninvasive methods have been proven to be reliable alternatives for monitoring reproductive function in both captive and free-ranging animals. subsequently, ...201930246895
beira baixa hostels. 202020991183
pediatric emergency care in a low-income country: characteristics and outcomes of presentations to a tertiary-care emergency department in mozambique.an effective pediatric emergency care (pec) system is key to reduce pediatric mortality in low-income countries. while data on pediatric emergencies from these countries can drive the development and adjustment of such a system, they are very scant, especially from africa. we aimed to describe the characteristics and outcomes of presentations to a tertiary-care pediatric emergency department (ped) in mozambique.202033147242
impact of temperature change from admission to day one on neonatal mortality in a low-resource setting.thermal control after birth is an essential part of neonatal care. however, the relationship between neonatal temperature at and after admission is unknown. this study aimed to evaluate the change between neonatal temperature at admission and at day 1, and its impact on mortality.202033097025
al exposure increases proline levels by different pathways in an al-sensitive and an al-tolerant rye genotype.aluminium (al) toxicity limits crop productivity, particularly at low soil ph. proline (pro) plays a role in protecting plants against various abiotic stresses. using the relatively al-tolerant cereal rye (secale cereale l.), we evaluated pro metabolism in roots and shoots of two genotypes differing in al tolerance, var. riodeva (sensitive) and var. beira (tolerant). most enzyme activities and metabolites of pro biosynthesis were analysed. al induced increases in pro levels in each genotype, but ...202033009431
emergency paediatric blood transfusion practices in mozambique.to analyse adherence to world health organization (who) indications for transfusion requests and capacity to meet the demand in the paediatric emergency units of a tertiary hospital in mozambique.202032990353
high burden of self-reported sexually transmitted infections among key populations in mozambique: the urgent need for an integrated surveillance system.key populations - men who have sex with men (msm), female sex workers (fsw) and people who inject drugs (pwid) - are at high risk for sexually transmitted infections (sti) given their sexual risk behaviours along with social, legal and structural barriers to prevention, care and treatment services. the purpose of this secondary analysis is to assess the prevalence of self-reported stis and to describe associated risk factors among participations of the first biological behavioural surveillance ( ...202032854638
population size estimate of men who have sex with men, female sex workers, and people who inject drugs in mozambique: a multiple methods approach.accurate estimates of key population size are necessary to design programs and policies to prevent and reduce new hiv infections and to monitor the dynamics of the epidemic. the first bio-behavioral surveillance surveys, with population size estimation activities, were conducted in mozambique in 2010 to 2014.202032815901
kaolin, ascophyllum nodosum and salicylic acid mitigate effects of summer stress improving hazelnut quality.various strategies are needed to mitigate the negative impact on or to increase fruit quality. the effect of spraying kaolin (k), ascophyllum nodosum (an) and salicylic acid (sa), in trees with and without irrigation, on quality and sensorial attributes of hazelnut (grada de viseu cultivar) was investigated during two consecutive years (2016 and 2017) in a commercial orchard located in moimenta da beira, portugal.202032648605
population size estimate of men who have sex with men, female sex workers and people who inject drugs in mozambique-a multiple methods approach.accurate estimates of key population size are necessary to design programs and policies to prevent and reduce new hiv infections and to monitor the dynamics of the epidemic. the first bio-behavioral surveillance (bbs) surveys, with population size estimation activities, were conducted in mozambique in 2010-2014.202032530856
comparative assessment of pretreatment strategies for production of microalgae-based biodiesel from locally isolated chlorella homosphaera.the yield and quality of lipids extracted from microalgal biomass are critical factors in the production of microalgae-based biodiesel. the green microalga chlorella homosphaera, isolated from beira lake, colombo, sri lanka was employed in the present study to identify the effect of chlorophyll removal and cell disruption methods on lipid extraction yield, fatty acid methyl ester (fame) profile and quality parameters of biodiesel; including cetane number (cn), iodine value (iv), degree of unsatu ...202032507481
comparing empathy in medical students of two portuguese medicine schools.empathy is paramount in the doctor-patient relationship being a comprehensive and multidimensional concept. self-ratings of empathy change across the years of medical education only when the jefferson scale of physicians empathy is used, with a worrying decrease being found throughout the years in medicine schools. as there are only few studies on the factors influencing medical student's empathy, particularly of the curricular model, this study aimed to compare the levels of empathy of medicine ...202032404095
autochthonous starter cultures are able to reduce biogenic amines in a traditional portuguese smoked fermented sausage.traditional smoked fermented sausages are highly appreciated in portugal and are mostly manufactured according to traditional procedures. the aim of the present work was to evaluate the effect of autochthonous starter cultures on the safety and quality of a smoked fermented sausage, painho da beira baixa (pbb), preserving its sensory quality. physicochemical parameters, namely ph and water activity (aw), microbiological parameters, biogenic amines, colour, texture profile and sensory attributes ...202032397076
using hospital auxiliary worker and 24-h tb services as potential tools to overcome in-hospital tb delays: a quasi-experimental study.in-hospital logistic management barriers (lmb) are considered to be important risk factors for delays in tb diagnosis and treatment initiation (tb-dt), which perpetuates tb transmission and the development of tb morbidity and mortality. we assessed the contribution of hospital auxiliary workers (haws) and 24-h tb laboratory services using xpert (24h-xpert) on the delays in tb-dt and tb mortality at beira central hospital, mozambique.202032245488
hiv-exposed infant follow-up in mozambique: formative research findings for the design of a cluster randomized controlled trial to improve testing and art initiation.early infant diagnosis (eid) of hiv-exposed and initiation of hiv-positive infants on anti-retroviral therapy (art) requires a well-coordinated cascade of care. loss-to-follow-up (ltfu) can occur at multiple steps and effective eid is impeded by human resource constraints, difficulty with patient tracking, and long waiting periods. the objective of this research was to conduct formative research to guide the development of an intervention to improve the pediatric hiv care cascade in central moza ...202032183779
cancer in mozambique: results from two population-based cancer registries.results from two recently established population-based registries in mozambique are reported: beira in the central region (2014-2017) and maputo, the capital city, in the south (2015-2017). the results are compared to those from maputo (lourenço marques at the time) in 1956-1960 (appearing cancer incidence in five continents vol 1), and with estimated incidence rates from other regions of africa. the elevated prevalence of hiv infection (12.6% of adults in 2018) results in high rates for hiv-rel ...202032142162
phylogenomic assessment of drug-resistant mycobacterium tuberculosis strains from beira, mozambique.mozambique is a high-burden tuberculosis (tb) country where tb/hiv co-infection and drug resistant tb (dr-tb) incidence is increasing. whole genome sequencing (wgs) comprehensively describes the molecular epidemiology of tb, allows prediction of dr-tb phenotypes, lineages strains identification and better understanding of transmission chains.202032063558
national tb program shortages as potential factor for poor-quality tb care cascade: healthcare workers' perspective from beira, mozambique.mozambique is one of the countries with the deadly implementation gaps in the tuberculosis (tb) care and services delivery. in-hospital delays in tb diagnosis and treatment, transmission and mortality still persist, in part, due to poor-quality of tb care cascade.202032059032
access to health services for men who have sex with men and transgender women in beira, mozambique: a qualitative study.hiv prevalence and incidence are higher among key populations including men who have sex with men (msm) and transgender women in low and middle income countries, when compared to the general population. despite world health organisation guidelines on the provision of services to key populations recommending an evidence-based, culturally relevant and rights-based approach, uptake of hiv services in many resource-limited and rights-constrained settings remains low. médecins sans frontières (msf) h ...202031999760
economic costs of violence against women in mozambique.huge efforts have been made to make society aware of the concerns of violence against women (vaw). hiding this phenomenon creates obstacles to quantify and clearly understand related aspects as well as leads to barriers to undertake actions for the reduction or elimination of vaw. the aim of this study is to estimate costs associated with vaw and produce data that will help in the design of strategies for the reduction or elimination of vaw. the economic cost of vaw was calculated for the cities ...202031984827
multicentre study of pressure ulcer point prevalence in a portuguese region.to conduct an exploratory investigation concerning the prevalence of pressure ulcers in different care settings, in the portuguese region of cova da beira.202031796241
schistosomal appendicitis: case series and systematic literature review.globally, schistosomiasis affects at least 240 million people each year with a high proportion of cases in sub-saharan africa. the infection presents a wide range of symptoms mainly at the gastrointestinal and urogenital level. cases of schistosomiasis-related appendicitis are seldom reported. the aim of the present study is to identify the prevalence of schistosomiasis-related appendicitis in beira, mozambique and compare to global prevalence.202134166369
laparoscopy in low-income countries: 10-year experience and systematic literature review.laparoscopy is a procedure that ultimately reduces hospital stay time and speeds up post-operative recovery. it is mainly performed in high-income countries but its implementation in many low- and middle-income countries (lmics) is increasing. however, no aggregate data exist regarding the outcomes of this procedure in resource-limited settings. we retrospectively reviewed all cases of laparoscopy recorded from january 2007 to march 2017 at the department of surgery of beira to assess the relate ...202134071312
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