Publications

production of d: -tagatose, a functional sweetener, utilizing alginate immobilized lactobacillus fermentum cgmcc2921 cells.	d: -tagatose is a ketohexose that can be used as a novel functional sweetener in foods, beverages, and dietary supplements. this study was aimed at developing a high-yielding d: -tagatose production process using alginate immobilized lactobacillus fermentum cgmcc2921 cells. for the isomerization from d: -galactose into d: -tagatose, the immobilized cells showed optimum temperature and ph at 65 °c and 6.5, respectively. the alginate beads exhibited a good stability after glutaraldehyde treatment ...	2011	22203394
the effect of inactivated lactobacillus lb fermented culture medium on symptom severity: observational investigation in 297 patients with diarrhea-predominant irritable bowel syndrome.	introduction: little is known about the intensity of symptoms of diarrhea-predominant ibs (ibs-d) or the consequences of the disease on patients' health-related quality of life (hrqol). this observational investigation assessed the symptoms (abdominal pain, bloating, number of stools per day, and stool consistency), impact on hrqol, and consequence on anal continence in 297 patients with ibs-d before and after 1 month of probiotic treatment with lacteol (inactivated lactobacillus lb plus ferment ...	2011	22179215
the microbial diversity of water kefir.	the microbial diversity of water kefir, made from a mixture of water, dried figs, a slice of lemon and sucrose was studied. the microbial consortia residing in the granules of three water kefirs of different origins were analyzed. a collection of 453 bacterial isolates was obtained on different selective/differential media. bacterial isolates were grouped with randomly amplified polymorphic dna (rapd)-pcr analyses. one representative of each rapd genotype was identified by comparative 16s rdna g ...	2011	22000549
effect of pretreatment with lactobacillus gasseri oll2716 on first-line helicobacter pylori eradication therapy.	background: helicobacter pylori eradication clearly decreases peptic ulcer recurrence rates. h. pylori eradication is achieved in 70 to 90% of cases, but treatment failures due to poor patient compliance and resistant organisms do occur. lactobacillus gasseri can suppress both clarithromycin-susceptible and -resistant strains of h. pylori in vitro. aim: to determine the effect of pretreatment with l. gasseri- containing yogurt on h. pylori eradication, we conducted a randomized, controlled clini ...	2011	22098133
antibiosis of vineyard ecosystem fungi against food-borne microorganisms.	fermentation extracts from fungi isolated from vineyard ecosystems were tested for antimicrobial activities against a set of test microorganisms, including five food-borne pathogens (staphylococcus aureus ep167, acinetobacter baumannii (clinically isolated), pseudomonas aeruginosa pao1, escherichia coli o157:h7 (cect 5947) and candida albicans my1055) and two probiotic bacteria (lactobacillus plantarum lch17 and lactobacillus brevis lch23). a total of 182 fungi was grown in eight different media ...	2011	22044674
effects of feeding potato pulp on cholesterol metabolism and its association with cecal conditions in rats.	to clarify the functional properties of potato pulp (pp), a waste product resulting from extraction of starch from potatoes, we examined the effects of pp on cholesterol metabolism and cecal conditions in rats. plasma total cholesterol (t-chol) levels were lower in rats fed a pp-supplemented diet for four weeks than in those fed a control diet. cecal ph was lowered due to an increase in the levels of cecal total short-chain fatty acids, especially butyrate, in the pp group compared to the contro ...	2011	21948633
the effect of using different probiotic cultures on conjugated linoleic acid (cla) concentration and fatty acid composition of white pickle cheese.	pickle white cheeses were produced from whole milk with five different probiotic cultures (enterococcus faecium, lactobacillus paracasei, bifidobacterium longum, bifidobacterium bifidum and lactobacillus acidophilus). conjugated linoleic acid (cla) content of cheeses ranged from 3.52 to 3.92 mg/g. probiotic differences and storage process have not affected the cla contents of the samples statistically. there was no correlation between the cla content of all probiotic cheeses and saturated fatty ...	2011	22166042
effect of lactobacillus plantarum and l-arginine against endotoxin-induced liver injury in a rat model.	use of probiotics, alone or as adjunct to other established therapies, has been reported to have potential benefits. recently, we have reported protective potential of probiotic against salmonella-induced liver injury. however, co-supplementation with prebiotics did not result in meaningful synergism at systemic level. owing to the action of probiotics at the mucosal level and of arginine at systemic level, the present study was designed to evaluate the effect of lactobacillus plantarum alone or ...	2011	21958471
assessing the adhesion of putative indigenous probiotic lactobacilli to human colonic epithelial cells.	background & objectives: adherence of bacteria to epithelial cells and mucosal surfaces is a key criterion for selection of probiotic. we assessed the adhesion property of selected indigenous probiotic lactobacillus strains based on their hydrophobicity and ability to adhere to human epithelial cells. methods: five human faecal lactobacillus isolates, one from buffalo milk and one from cheese were assessed for hydrophobicity following the microbial adhesion to hydrocarbons (math) method and colo ...	2011	22199106
bacterial diversity in philippine fermented mustard (burong mustasa) as revealed by 16s rrna gene analysis.	previous studies on the bacterial profile of burong mustasa, a traditional philippine fermented food, had been conducted using culture-dependent techniques. since these methods may underestimate the total microbiota of a sample, a culture-independent study was done to determine the bacterial diversity in burong mustasa through molecular biology techniques. bacterial dna was isolated from fermented mustard samples at different stages of fermentation. the isolated genomic dna was amplified by pcr ...	2011	22146686
lactobacillus delbrueckii subsp. sunkii subsp. nov., isolated from sunki, a traditional japanese pickle.	four strains isolated from a traditional japanese non-salted pickle and initially identified as lactobacillus delbrueckii could not be assigned to a definite subspecies because molecular identification and phenotypic characteristics did not agree with those of recognized subspecies of l. delbrueckii. hybridization of total dna (> 88.7% against type strains of the other three recognized subspecies), phylogenetic analyses based on 16s rrna gene sequences, amplified fragment length polymorphism (af ...	2011	22199209
lipoteichoic acid from lactobacillus plantarum induces nitric oxide production in the presence of interferon-+¦ in murine macrophages.	lipoteichoic acid (lta) is a major immuno-stimulating component of gram-positive bacteria. lta from the beneficial bacterium lactobacillus plantarum induces weak nitric oxide (no) production in murine macrophages. currently, it is not clear if lta from l. plantarum is able to stimulate the innate immune response, even in the presence of inflammation. in the present study, we prepared highly pure and structurally intact lta from l. plantarum and investigated its ability to induce no in the presen ...	2011	21835472
lactobacillus brevis strain 1e1 administered to piglets through milk supplementation prior to weaning maintains intestinal integrity after the weaning event.	early colonisation in the gastrointestinal tract by commensal microbes influences the progressive development and maturity of digestive and immune system functionality in the neonate. application of strategically selected direct-fed microbials to neonatal pigs may provide an opportunity to dictate a portion of the intestinal microbial community and exert a beneficial influence on these developmental processes. experiments were conducted to determine the effects of early administration of lactoba ...	2011	21831788
genome sequence of lactobacillus johnsonii pf01, isolated from piglet feces.	lactobacillus johnsonii pf01, an autochthonous bacterium of the gastrointestinal tract, was isolated from a fecal sample from a piglet. the strain adhered specifically to the duodenal and jejunal epithelial cells of the piglet and had high bile resistance activity. here we report the genomic sequence of l. johnsonii pf01.	2011	21742886
oral treatment of chickens with lactobacilli influences elicitation of immune responses.	commensal microbes in the intestine are in constant interaction with host cells and play a role in shaping the immune system. lactobacillus acidophilus, lactobacillus reuteri, and lactobacillus salivarius are members of the chicken intestinal microbiota and have been shown to induce different cytokine profiles in mononuclear cells in vitro. the objective of the present study was to examine the effects of these bacteria individually or in combination on the induction of antibody- and cell-mediate ...	2011	21734067
combined influence of fermentation and drying conditions on survival and metabolic activity of starter and probiotic cultures after low-temperature vacuum drying.	the influence of low temperature vacuum drying process parameters on the survival, metabolic activity and residual water content of three different bacterial strains (lactobacillus paracasei ssp. paracasei, lactobacillus delbrueckii ssp. bulgaricus and bifidobacterium lactis) was investigated. shelf temperature and chamber pressure were varied and optimized by response surface methodology with regard to survival and residual water content. it is shown that the survival rate after low temperature ...	2011	21723344
[effectiveness of cultured milk foods, enriched by bifidus bacteria and lactobacillus rhamnosis gg (atcc 53103, lgg) in patients with slackening of motility function of intestines].	in patients who consumed yogurt and kefir, enriched by bifidus bacteria and lactobacillus rhamnosis gg, improvement of large intestine motor function was found.	2011	21842754
draft genome sequence of lactobacillus mali kctc 3596.	we announce the draft genome sequence of the type strain lactobacillus mali kctc 3596 (2,652,969 bp, with a g+c content of 36.0%), which is one of the most prevalent lactic acid bacteria present during the manufacturing process of apple juice. the genome consists of 122 large contigs (>100 bp). all of the contigs were assembled by newbler assembler 2.3 (454 life science).	2011	21742889
fermentation of korean red ginseng by lactobacillus plantarum m-2 and its immunological activities.	we investigated ginsenoside transformation by fermentation of red ginseng with lactobacillus plantarum m-2. we also examined the anti-metastasis and immune-stimulating activities of etoh extracts of fermented red ginseng (frg-e) in animal and human subjects. total sugar decreased from 85.5 mg ml(-1) to 44.1 mg ml(-1) with increasing culture time during the fermentation with l. plantarum m-2. uronic acid content reached a maximum level (534.3 µg ml(-1)) at 3 days of fermentation and decreased the ...	2011	21845445
biotechnological production of vitamin b2-enriched bread and pasta.	lactic acid bacteria (lab) were obtained from durum wheat flour samples and screened for roseoflavin-resistant variants to isolate natural riboflavin-overproducing strains. two riboflavin-overproducing strains of lactobacillus plantarum isolated as described above were used for the preparation of bread (by means of sourdough fermentation) and pasta (using a prefermentation step) to enhance their vitamin b2 content. pasta was produced from a monovarietal semolina obtained from the durum wheat cul ...	2011	21678896
host immunity in the protective response to nasal immunization with a pneumococcal antigen associated to live and heat-killed lactobacillus casei.	abstract:	2011	21834957
hygienic quality and antibiotic resistance profile of sliced butchery.	in order to investigate the microbiological quality of different meat products on the greek market, 200 samples were collected from the following preparations: boiled turkey (n=50), boiled pork ham (n=50), smoked turkey (n=50) and smoked pork ham (n=50). in all cold meat preparations clostridium perfringens vegetative and spore forms, staphylococcus aureus, escherichia coli and other clostridium sp lec(-), as well as lactobacillus, bacillus sp. and salmonella sp. were recovered. for instance bac ...	2011	21722746
kinetic modelling and microbial community assessment of anaerobic biphasic fixed film bioreactor treating distillery spent wash.	anaerobic digestion, microbial community structure and kinetics were studied in a biphasic continuously fed, upflow anaerobic fixed film reactor treating high strength distillery wastewater. treatment efficiency of the bioreactor was investigated at different hydraulic retention times (hrt) and organic loading rates (olr 5-20 kg cod môü+-¦ dôü+-¦). applying the modified stover-kincannon model to the reactor, the maximum removal rate constant (u(max)) and saturation value constant (k(b)) were fou ...	2011	21704352
engineering tenofovir loaded chitosan nanoparticles to maximize microbicide mucoadhesion.	the objective of this study was to engineer a model anti-hiv microbicide (tenofovir) loaded chitosan based nanoparticles (nps). box-behnken design allowed to assess the influence of formulation variables on the size of nps and drug encapsulation efficiency (ee%) that were analyzed by dynamic light scattering and uv spectroscopy, respectively. the effect of the nps on vaginal epithelial cells and lactobacilluscrispatus viability and their mucoadhesion to porcine vaginal tissue were assessed by cy ...	2011	21704704
immunological and microbiologic changes during caries development in young children.	we explored the association between caries development, colonization with caries-associated microflora, and immunity as children begin the transition to mixed dentition. forty children received dental examinations at 3-4 years of age, repeated a year later. children were grouped into caries-free (n = 23; cf) and caries-active (n = 17; ca ôëñ3 new lesions on follow-up). salivary iga and iga antibody to streptococcus mutans virulence epitopes were measured by luminex assay. mutans streptococci (ms ...	2011	21822016
treating bugs with bugs: the role of probiotics as adjunctive therapy for helicobacter pylori.	to review the literature on the role of probiotics as adjunctive therapy in the treatment of helicobacter pylori infections.	2011	21693698
impact of bile salt adaptation of lactobacillus delbrueckii subsp. lactis 200 on its interaction capacity with the gut.	in a previous work, bile-salt-resistant derivatives were obtained from non-intestinal lactobacilli. the aim of this work was to investigate the impact of bile adaptation of lactobacillus delbrueckii subsp. lactis 200 on morphology, surface properties, in-ávivo interaction capacity with the gut and ability to activate the gut immune response. electron microscopy studies, growth kinetics in the presence of bovine and porcine bile, the capacity to deconjugate bile acids, hydrophobicity, autoaggrega ...	2011	21820507
short- and long-term adaptation to ethanol stress and its cross-protective consequences in lactobacillus plantarum.	this paper describes the molecular responses of lactobacillus plantarum wcfs1 toward ethanol exposure. global transcriptome profiling using dna microarrays demonstrated adaptation of the microorganism to the presence of 8% ethanol over short (10-min and 30-min) and long (24-h) time intervals. a total of 57 genes were differentially expressed at all time points. expression levels of an additional 859 and 873 genes were modulated after 30 min and 24 h of exposure to the solvent, respectively. etha ...	2011	21705551
anticarcinogenic effect of probiotic fermented milk and chlorophyllin on aflatoxin-b1-induced liver carcinogenesis in rats.	the present investigation was carried out to evaluate the hepatoprotective effect of probiotic fermented milk (fm) containing lactobacillus rhamnosus gg and lactobacillus casei strain shirota, alone as well as in combination with chlorophyllin (chl) as an antioxidant agent in male wistar rats administered aflatoxin-b1 (afb1). afb1 was injected intraperitoneally at the rate of 450-á++g/kg body weight per animal twice a week for 6 weeks, maintaining an equal time interval between the two consecuti ...	2011	21816119
application of a novel thermostable nad(p)h oxidase from hyperthermophilic archaeon for the regeneration of both nad(+) and nadp(+).	a novel thermostable nad(p)h oxidase from the hyperthermophilic archaeon thermococcus kodakarensis kod1 (tknox) catalyzes oxidation of nadh and nadph with oxygen from atmospheric air as an electron acceptor. although the optimal temperature of tknox is >90-¦c, it also shows activity at 30-¦c. this enzyme was used for the regeneration of both nadp(+) and nad(+) in alcohol dehydrogenase (adh)-catalyzed enantioselective oxidation of racemic 1-phenylethanol. nadp(+) regeneration at 30-¦c was perform ...	2011	21830202
bioconversion of ovine scotta into lactic acid with pure and mixed cultures of lactic acid bacteria.	scotta is the main by-product in the making of ricotta cheese. it is widely produced in southern europe and particularly in italy where it represents a serious environmental pollutant due to its high lactose content. with the aim of evaluating whether scotta bioconversion into lactic acid can be considered as an alternative to its disposal, besides providing it with an added value, here the growth, fermentative performances, and lactic acid productions of pure and mixed cultures of lactobacillus ...	2011	21739193
modification of technical properties of lactobacillus johnsonii ncc 533 by supplementing growth medium with unsaturated fatty acids.	the aim of this study was to investigate the influence of supplementing growth media with unsaturated fatty acids on the technical properties of the probiotic strain lactobacillus johnsonii ncc 533, such as heat and acid tolerance, and inhibition of salmonella typhimurium infection. our results showed that the membrane composition and morphology of l. johnsonii ncc 533 was significantly changed by supplementing a minimal lactobacillus media with oleic, linoleic and linolenic acids. the ratio of ...	2011	21821758
spontaneous organic cocoa bean box fermentations in brazil are characterized by a restricted species diversity of lactic acid bacteria and acetic acid bacteria.	spontaneous organic cocoa bean box fermentations were carried out on two different farms in brazil. physical parameters, microbial growth, bacterial species diversity [mainly lactic acid bacteria (lab) and acetic acid bacteria (aab)], and metabolite kinetics were monitored, and chocolates were produced from the fermented dry cocoa beans. the main end-products of the catabolism of the pulp substrates (glucose, fructose, and citric acid) by yeasts, lab, and aab were ethanol, lactic acid, mannitol, ...	2011	21839382
[the influence assessment of probiotic fermented milk products on intestinal microflora, hematological indices and cellular immunity in rats (report 1)].	influence of probiotic fermented milk products on the intestinal flora, hematological parameters and immune status of the experiment in vivo at rats is studied. entering in digestive tract of probiotic strains of lactobacillus acidophilus nk-1 and bifidobacterium bifidum 791 at the level of hundreds of millions cfu in a day (from 1,7 x 10(8) to 9 x 10(8) cfu) in composition fermented milk products renders on the whole positive, but not significant statistically influence on the indexes of colon ...	2011	21842751
transcriptional analysis of lactobacillus brevis to n-butanol and ferulic acid stress responses.	the presence of anti-microbial phenolic compounds, such as the model compound ferulic acid, in biomass hydrolysates pose significant challenges to the widespread use of biomass in conjunction with whole cell biocatalysis or fermentation. currently, these inhibitory compounds must be removed through additional downstream processing or sufficiently diluted to create environments suitable for most industrially important microbial strains. simultaneously, product toxicity must also be overcome to al ...	2011	21829598
kinetic behaviour of free lipase and mica-based immobilized lipase catalyzing the synthesis of sugar esters.	the utilization of natural mica as a biocatalyst support in kinetic investigations is first described in this study. the formation of lactose caprate from lactose sugar and capric acid, using free lipase (free-crl) and lipase immobilized on nanoporous mica (ner-crl) as a biocatalyst, was evaluated through a kinetic study. the apparent kinetic parameters, k(m) and v(max), were determined by means of the michaelis-menten kinetic model. the ping-pong bi-bi mechanism with single substrate inhibition ...	2011	21821960
linoleate isomerase activity occurs in lactic acid bacteria strains and is affected by ph and temperature.	aims:ôçé to investigate the ability of lactic acid bacteria (lab) to convert linoleic acid (la) and +¦-linolenic acid (+¦-lna) to conjugated linoleic acid (cla) and conjugated linolenic acid (clna), respectively. to assess ph and temperature influences on cla and clna production by lactobacillus sakei lmg 13558. methods and results:ôçé a screening of 48 lab yielded one lactobacillus curvatus, five lactobacillus plantarum and four lact.-ásakei strains displaying linoleate isomerase (lai) activity ...	2011	21699633
poly(dimethyl siloxane) surface modification with biosurfactants isolated from probiotic strains.	depending on the final application envisaged for a given biomaterial, many surfaces must be modified before use. the material performance in a biological environment is mainly mediated by its surface properties that can be improved using suitable modification methods. the aim of this work was to coat poly(dimethyl siloxane) (pdms) surfaces with biosurfactants (bss) and to evaluate how these compounds affect the pdms surface properties. bss isolated from four probiotic strains (lactococcus lactis ...	2011	21681946
identification and characterization of potential performance-related gut microbiotas in broiler chickens across various feeding trials.	three broiler feeding trials were investigated in order to identify gut bacteria consistently linked with improvements in bird performance as measured by feed efficiency. trials were done in various geographic locations and varied in diet composition, broiler breed, and bird age. gut microbial communities were investigated using microbial profiling. eight common performance-linked operational taxonomic units (otus) were identified within both the ilea (180, 492, and 564-566) and ceca (140-142, 2 ...	2011	21742925
expression of lactobacillus brevis ioeb 9809 tyrosine decarboxylase and agmatine deiminase genes in wine correlates with substrate availability.	aims:ôçé lactobacillus brevis ioeb 9809 is able to produce both tyramine and putrescine via tyrosine decarboxylase and agmatine deiminase enzymes, respectively, when cultured on synthetic media. the aims of this study were to assess the expression of l.-ábrevis ioeb 9809 tdc and agua1 genes, during wine fermentation and to evaluate the effect of substrate availability and ph on tdc and agua1 expression, as well as on biogenic amine production and l.-ábrevis viability. methods and results:ôçé the ...	2011	21740449
typing of bacteriophages by randomly amplified polymorphic dna (rapd)-pcr to assess genetic diversity.	the recent boom in phage therapy and phage biocontrol requires the design of suitable cocktails of genetically different bacteriophages. the current methods for typing phages need significant quantities of purified dna, may require a priori genetic information and are cost and time consuming. we have evaluated the randomly amplified polymorphic dna (rapd)-pcr technique to produce unique and reproducible band patterns from 26 different bacteriophages infecting staphylococcus epidermidis, staphylo ...	2011	21692832
lactobacillus johnsonii crl1647, isolated from apis mellifera l. bee-gut, exhibited a beneficial effect on honeybee colonies.	lactobacillus johnsonii crl1647, isolated from the intestinal tract of a honeybee and selected due to its high lactic acid production, was assayed as a monoculture on bee colony performance. it was delivered to the bees on a one litre of 125 g/l sugar-cane syrup with a final concentration of 105 cfu/ml lactobacilli. the bees accepted the new nourishment, which was consumed within 24-48 h and was administered in two independent trials (every 14-15 days for 3 consecutive months in one case, and on ...	2011	21831787
annotated genome sequence of lactobacillus pentosusmp-10, which has probiotic potential, from naturally fermented alorena green table olives.	lactobacillus pentosusmp-10 was isolated from brines of naturally fermented alore+¦a green table olives. mp-10 has potential probiotic traits, including inhibition of human pathogenic bacteria, survival at low ph (1.5), and bile salt tolerance (3%). here, we report for the first time the annotated genome sequence of l. pentosus.	2011	21705590
tlr ligands of lactobacillus sakei lk-117 isolated from seed mash for brewing sake are potent inducers of il-12.	many studies have investigated the immunostimulatory effects of bacteria, such as the anti-allergic effects of lactic acid bacteria (lab) and lab-fermented milk. importantly, these anti-allergic effects have been observed for both viable and nonviable bacteria. however, there are no reported immunological effects of lab isolated from kimoto, the traditional yeast starter culture used for brewing sake, which also involves spontaneous lactate fermentation. in this study, we determined whether the ...	2011	21741305
synthesis of +¦-aminobutyric acid by expressing lactobacillus brevis-derived glutamate decarboxylase in the corynebacterium glutamicum strain atcc 13032.	purpose of work: purpose of this work is to synthesize +¦-aminobutyric acid by glutamate-producing species expressing lactobacillus brevis-derived glutamate decarboxylase genes, i.e. recombinant corynebacterium glutamicum strains, which directly convert endogenous l: -glutamate precursor into +¦-aminobutyric acid (gaba) through single-step fermentation. to express exogenous glutamate decarboxylase (gad) in an l: -glutamate-producing strain, lactobacillus brevis lb85, which can produce gaba, was ...	2011	21826397
quantitative transcript analysis of the inducible expression system psip: comparison of the overexpression of lactobacillus spp. +¦-galactosidases in lactobacillus plantarum.	abstract:	2011	21696579
incorporation of probiotic bacteria in whey cheese: decreasing the risk of microbial contamination.	for dairy products that are consumed fresh, contamination by spoilage microorganisms and pathogens from the environment is a major concern. contamination has been associated with a number of outbreaks of foodborne illnesses; however, consistent data pertaining to the microbial safety of whey cheeses specifically have not been reported. hence, the goals of this research effort were (i) to manufacture a probiotic whey cheese with bifidobacterium animalis and lactobacillus casei and (ii) to assess ...	2011	21740724
oral microflora in infants delivered vaginally and by caesarean section.	international journal of paediatric dentistry 2011 background.ôçé early in life, vaginally delivered infants exhibit a different composition of the gut flora compared with infants delivered by caesarean section (c-section); however, it is unclear whether this also applies to the oral cavity. aim.ôçé to investigate and compare the oral microbial profile between infants delivered vaginally and by c-section. design.ôçé this is a cross-sectional case-control study. eighty-four infants delivered eith ...	2011	21702851
gastroesophageal reflux is not associated with dental erosion in children.	background & aims: dental erosion is a complication of gastroesophageal reflux (ger) in adults; in children, it is not clear if ger has a role in dental pathologic conditions. dietary intake, oral hygiene, high bacterial load, and decreased salivary flow might contribute independently to ger development or dental erosion, but their potential involvement in dental erosion from ger is not understood. we investigated the prevalence of dental erosion among children with and without ger symptoms, and ...	2011	21820389
protection against atypical aeromonas salmonicida infection in common carp, cyprinus carpio l., by oral administration of a mixed microbial culture of lactobacillus paracasei, pichia membranifaciens and saccharomyces cereviciae.	a microbial culture was prepared by co-cultivation of lactobacillus paracasei, pichia membranifaciens and saccharomyces cereviciae for 48 hr at 30 c in rice bran extract medium, supplemented with dextrose. oral administration of the resulting non-viable heat-inactivated microbial culture to common carp, cyprinus carpio l., delivered in feed for four weeks, induced effective protection against experimental atypical aeromonas salmonicida infection which causes "ulcer disease". after challenge of t ...	2011	21685718
characterization of two safe enterococcus strains producing enterocins isolated from egyptian dairy products.	five bacterial cocci isolates were selected from a wide pool of 503 isolates collected from traditional egyptian dairy products on the basis of their inhibitory activities against lactobacillus brevis f145, lactobacillus bulgaricus 340, enterococcus faecium hklhs, listeria ivanovii atcc, listeria innocua cip 80.11 and listeria monocytogenes egde 107776. these 5 isolates were identified as e. faecium tx1330 and e. faecium e980 by 16s rdna amplification and sequencing. the antibacterial activity o ...	2011	21831786
expression of lactobacillus pentosus b96 bacteriocin genes under saline stress.	this research studied the influence of sodium chloride on bacteriocin activity of table olives' strain lactobacillus pentosus b96. the strain was cultured in mrs under different nacl concentrations (0, 4, 6 and 8%, in w/v). in mrs, maximum bacteriocin activity was achieved 9-áh later. a medium containing 4 or 6% nacl (w/v) increased the total bioactivity of the strain and an 8% nacl reduced it. real-time pcr was used to monitor the genetic expression of the bacteriocin genes plna, plnb, plnc, pl ...	2011	21839383
the manitoba inflammatory bowel disease cohort study: a prospective longitudinal evaluation of the use of complementary and alternative medicine services and products.	objective to determine the prevalence of complementary and alternative medicine (cam) use over time in a population-based cohort of patients with inflammatory bowel disease (ibd). methods the manitoba ibd cohort study is a longitudinal, population-based study of multiple determinants of health outcomes in an ibd cohort. participants completed semi-annual surveys, and annual in-person interviews. enquiries about the use of 12 types of cam service providers and 13 cam products, based on items from ...	2011	21836028
the inhibitory effects of wine phenolics on lysozyme activity against lactic acid bacteria.	the lysozyme of hen's egg white is used in winemaking to control spontaneous lactic acid bacteria (lab). a total of eight lab strains, isolated from grape must and wine, were used to assess the inhibitory effects of wine phenolics on lysozyme activity. the presence of phenolics, extracted from grape pomace, in growth medium reduced the mortality rate due to the lysozyme activity. this effect was especially clear in the case of strains belonging to lactobacillus uvarum, pediococcus parvulus and o ...	2011	21683465
[influence of lactobacillus strains used in the production of dairy products on the agents of food poisoning].	study of antagonistic activity of 33 strains of lactobacillus isolated from the industrial preparation of fermented milk products, starter cultures and biologically active additives and products of natural fermentation. antagonistic activity was studied by agar diffusion method with holes. strains isolated from products of natural fermentation showed high degree of antagonistic action together with industrial strains.	2011	21842752
production of high amounts of 3-hydroxypropionaldehyde from glycerol by lactobacillus reuteri with strongly increased biocatalyst lifetime and productivity.	3-hydroxypropionaldehyde (3hpa) is a promising versatile substance derived from the renewable feedstock glycerol. it is a product of glycerol metabolism in lactobacillus reuteri. because of toxic effects, the biotechnological production is poor. in this work the biocatalyst lifetime and product formation could be drastically increased. in the established two-step process already applied, cells are grown in the first step under anaerobic conditions, and in the second step the immobilised or suspe ...	2011	21729774
effect of probiotic yogurt containing lactobacillus acidophilus and bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus.	the purpose of this study was to investigate the effects of probiotic and conventional yogurt on the lipid profile in type 2 diabetic people. in a randomized double-blind controlled trial, 60 people (23 males and 37 females) with type 2 diabetes and low-density lipoprotein cholesterol (ldl-c) greater than 2.6 mmol/l were assigned to 2 groups. participants consumed daily 300 g of probiotic yogurt containing lactobacillus acidophilus la5 and bifidobacterium lactis bb12 or 300 g of conventional yog ...	2011	21700013
crystal structure of +¦-galactosidase from lactobacillus acidophilus ncfm: insight into tetramer formation and substrate binding.	lactobacillus acidophilus ncfm is a probiotic bacterium known for its beneficial effects on human health. the importance of +¦-galactosidases (+¦-gals) for growth of probiotic organisms on oligosaccharides of the raffinose family present in many foods is increasingly recognized. here, the crystal structure of +¦-gal from l. acidophilus ncfm (lamel36a) of glycoside hydrolase (gh) family 36 (gh36) is determined by single-wavelength anomalous dispersion. in addition, a 1.58-+à-resolution crystallog ...	2011	21827767
interventions for prevention and treatment of vulvovaginal candidiasis in women with hiv infection.	vulvovaginal candidiasis (vvc) is one of the most common fungal infections that recur frequently in hiv infected women. symptoms of vvc are pruritis, discomfort, dyspareunia, and dysuria. vulval infection presents as a morbiliform rash that may extend to the thighs. vaginal infection is associated with white discharge, and plaques are seen on erythematous vaginal walls.even though rarely or never resulting in systemic fungal infection or mortality, left untreated these lesions contribute conside ...	2011	21833970
microbial dynamics during aerobic exposure of corn silage stored under oxygen barrier or polyethylene films.	the aims were to compare the effects of sealing forage maize with a new oxygen barrier film or with a conventional polyethylene film. this comparison would be during both ensilage and subsequent exposure of silage to air, and would include chemical, microbiological and molecular (dna and rna) assessments. the forage was inoculated with a mixture of lactobacillus buchneri, lb. plantarum, and enterococcus faecium and ensiled in polyethylene (pe) and oxygen barrier (ob) plastic bags. the oxygen per ...	2011	21821764
viability and delivery of immobilised lactobacillus reuteri dpc16 within calcium alginate gel systems during sequential passage through simulated gastrointestinal fluids.	the objective of the study was to design and produce calcium alginate beads that can deliver immobilised lactobacillus reuteri dpc16 to a target site of the colon in the gastrointestinal (gi) tract. in this study, several factors that might affect the effectiveness of calcium alginate gel beads entrapping l. reuteri dpc16 cells were investigated. an in vitro gi tract model was used to simulate the ph variation and the existence of enzymes. firstly, by varying the concentration of alginate at a c ...	2011	21831794
diversity of lactic acid bacteria associated with traditional fermented dairy products in mongolia.	spontaneous milk fermentation has a long history in mongolia, and beneficial microorganisms have been handed down from one generation to the next for use in fermented dairy products. the objective of this study was to investigate the diversity of lactic acid bacteria (lab) communities in fermented yak, mare, goat, and cow milk products by analyzing 189 samples collected from 13 different regions in mongolia. the lab counts in these samples varied from 3.41 to 9.03 log cfu/ml. fermented yak and m ...	2011	21700007
the genome sequence of the lactic acid bacterium, carnobacterium maltaromaticum atcc 35586 encodes potential virulence factors.	the genus carnobacterium belongs to the lactic acid bacteria and carnobacterium maltaromaticum is commonly found in modified atmosphere packed and vacuum packed fish and meat products as well as in live fish. this species has been described as a fish pathogenic organism but human clinical isolates have only been obtained at one occasion. to investigate the virulence potential we sequenced the entire genome of strain atcc 35586, isolated from a diseased salmon. when comparing the translated gene ...	2011	21704418
obesity-associated gut microbiota is enriched in lactobacillus reuteri and depleted in bifidobacterium animalis and methanobrevibacter smithii.	background:obesity is associated with increased health risk and has been associated with alterations in bacterial gut microbiota, with mainly a reduction in bacteroidetes, but few data exist at the genus and species level. it has been reported that the lactobacillus and bifidobacterium genus representatives may have a critical role in weight regulation as an anti-obesity effect in experimental models and humans, or as a growth-promoter effect in agriculture depending on the strains.objectives an ...	2011	21829158
in infants with 'colic'/persistent crying, administration of daily lactobacillus reuteri dsm 17938 was associated with reduced crying time at 1, 2 and 3 weeks.		2011	21719466
tocopherol and ascorbate have contrasting effects on the viability of microencapsulated lactobacillus rhamnosus gg.	the antioxidants, sodium ascorbate and tocopherol, have contrasting effects on the viability of microencapsulated lactobacillus rhamnosus gg (lgg) spray dried powders during storage (4 and 25-¦c; 32, 57 and 70% rh). the addition of tocopherol improved probiotic viability during storage while the incorporation of na-ascorbate alone or in combination with tocopherol had detrimental effects on probiotic survival. the beneficial effect of tocopherol is a consequence of its chemical antioxidative act ...	2011	21842832
genome sequence of lactobacillus cypricasei kctc 13900.	lactobacillus cypricasei kctc 13900 is important in the generation of particular flavors and in other ripening processes associated with specific cheeses. here, we announce the draft genome sequence of lactobacillus cypricasei kctc 13900, isolated from cheeses, and describe major findings from its annotation.	2011	21742864
a dairy product fermented by lactobacilli cancels the adverse effects of hypochlorhydria induced by a proton pump inhibitor on bone metabolism in growing rats.	the purpose of the present study is to investigate the effects of hypochlorhydria induced by proton pump inhibitor (ppi) administration and intake of a dairy product fermented by lactobacilli (dfl) on bone metabolism in growing rats. male rats, aged 3 weeks, were divided into two groups: a control group fed a casein-based diet and a group fed a dfl-based diet. each group was fed its respective experimental diets for 9 d. at day 5 of the feeding period, each group was divided into two subgroups: ...	2011	21736787
galactooligosaccharides derived from lactose and lactulose: influence of structure on lactobacillus, streptococcus and bifidobacterium growth.	the effect of structure on the fermentative properties of potential prebiotic trisaccharides derived from lactulose like 6'-galactosyl-lactulose (+¦-d-galactopyranosyl-(1ôåæ6)-+¦-d-galactopyranosyl-(1ôåæ4)-+¦-d-fructopyranose), 4'-galactosyl-lactulose (+¦-d-galactopyranosyl-(1ôåæ4)-+¦-d-galactopyranosyl-(1ôåæ4)-+¦-d-fructopyranose), and 1-galactosyl-lactulose (+¦-d-galactopyranosyl-(1ôåæ4)-+¦-d-fructopyranosyl-(1ôåæ1)-+¦-d-galactopyranose); and from lactose like 4'-galactosyl-lactose (+¦-d-galac ...	2011	21700354
evaluation of yogurt and various beverages as carriers of lactic acid bacteria producing 2-branched (1,3)-+¦-d-glucan.	probiotic cultures are increasingly being incorporated into a wide variety of food products. although lactobacilli and bifidobacteria are the most frequently used, other lactic acid bacteria (lab) have been reported to be potential probiotics. of these, the cider isolates pediococccus parvulus (strains 2.6 and cupv22) and lactobacillus suebicus cupv221 produce a 2-branched (1,3)-+¦-d-glucan exopolysaccharide that decreases serum cholesterol levels and affects the activation of human macrophages. ...	2011	21700011
Effect of grape polyphenols on lactic acid bacteria and bifidobacteria growth: Resistance and metabolism.	Food polyphenols are able to selectively modify the growth of susceptible micro-organisms. This study describes the effect of a flavan-3-ol enriched grape seed extract (GSE) on the growth of several lactic acid bacteria (LAB) and bifidobacteria and the ability of the resistant strains to metabolize these compounds. Streptococcus thermophilus, Lactobacillus fermentum, Lactobacillus acidophilus and Lactobacillus vaginalis strains showed a remarkable sensitivity to the phenolic extracts assayed, in ...	2011	21839384
pH-responsive nanoparticles releasing tenofovir intended for the prevention of HIV transmission.	This study is designed to test the hypothesis that tenofovir (TNF) or tenofovir disoproxil fumarate (TDF) loaded nanoparticles (NPs) prepared with a blend of poly(lactic-co-glycolic acid) (PLGA) and methacrylic acid copolymer (Eudragit-« S-100, or S-100) are noncytotoxic and exhibit significant pH-responsive release of anti-HIV microbicides in the presence of human semen fluid simulant (SFS). After NPs preparation by emulsification diffusion, their size, encapsulation efficiency (EE%), drug rele ...	2011	21736940
anti-inflammatory properties of dairy lactobacilli.	background: the intestinal microbiota plays an important role in human health through the modulation of innate immune responses. while selected commensal bacteria are marketed in specific probiotic products to control these responses, relatively little is known about the immune modulation potential of dairy bacteria that have principally been selected for their fermentation properties. the modulation of innate immune responses may reduce chronic inflammation in inflammatory bowel diseases like u ...	2011	21837773
Increasing free-energy (ATP) conservation in maltose-grown Saccharomyces cerevisiae by expression of a heterologous maltose phosphorylase.	Increasing free-energy conservation from the conversion of substrate into product is crucial for further development of many biotechnological processes. In theory, replacing the hydrolysis of disaccharides by a phosphorolytic cleavage reaction provides an opportunity to increase the ATP yield on the disaccharide. To test this concept, we first deleted the native maltose metabolism genes in Saccharomyces cerevisiae. The knockout strain showed no maltose-transport activity and a very low residual ...	2011	21684346
caries risk profile using the cariogram in governmental and private orthodontic patients at de-bonding.	abstract objectives: to analyze various caries-related factors in orthodontic patients at de-bonding, and to test the null hypothesis that there is no difference in caries risk between governmental and private orthodontic patients immediately after orthodontic treatment. materials and methods: a cross-sectional examination was carried out on 89 orthodontic patients aged 13-29 years, mean age 21.5 years. they were divided into two groups based on the center of treatment, governmenta ...	2011	21827234
toll-like receptor 2 monoclonal antibody or/and toll-like receptor 4 monoclonal antibody increase counts of lactobacilli and bifidobacteria in dextran sulfate sodium-induced colitis in mice.	background and aim: the accurate pathogenesis of ulcerative colitis (uc) is not yet well understood. recently, toll-like receptor 2 (tlr2), tlr4 and gut microbial flora have been proved as playing important roles in the process of uc. this study was to evaluate the effect of tlr2 and tlr4 monoclonal antibodies on gut microbial flora in dextran sulfate sodium (dss)-induced colitis in a mouse model. methods: we evaluated the effects of the tlr2 and tlr4 monoclonal antibodies on the development o ...	2011	21722182
agrowaste-based nanofibers as a probiotic encapsulant: fabrication and characterization.	this study explored the potential of soluble dietary fiber (sdf) from agrowastes, okara (soybean solid waste), oil palm trunk (opt), and oil palm frond (opf) obtained via alkali treatment, in the nanoencapsulation of lactobacillus acidophilus . sdf solutions were amended with 8% poly(vinyl alcohol) to produce nanofibers using electrospinning technology. the spinning solution made from okara had a higher ph value at 5.39 ± 0.01 and a higher viscosity at 578.00 ± 11.02 mpa·s (p < 0.05), which resu ...	2011	21711050
Lactobacillus brevis responds to flavonoids through KaeR, a LysR-type of transcriptional regulator.	The ability of transcription factors to respond to flavonoids as signal molecules was investigated in Lactobacillus brevis. Through in vitro screening of a small library of flavonoids, LVIS1989 (KaeR), a LysR-type transcriptional regulator (LTTR), was identified as responsive to kaempferol. The modulation of KaeR activity by flavonoids was characterized in vivo and in vitro. DNase I footprint assays identified the binding of KaeR at two distinctive sites, one in the intergenic region between LVI ...	2011	21819457
The influence of probiotics on the cervical malignancy diagnostics quality.	Probiotics help to provide an optimum balance in the intestines. Probiotics species competitive block toxic substances and growth of unwanted bacteria and yeast species while they compete for the space and food. Lactogyn is the first oral probiotics on Serbian market dedicated to maintaining a normal vaginal flora. Lactogyn contains two well studied probiotics strains - Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. Both of them are considered as probiotic agents with therapeutic ...	2011	22191313
spoilage characteristics of traditionally packaged ground beef with added lactic acid bacteria displayed at abusive temperatures.	growth of pathogenic organisms such as escherichia coli o157:h7 and salmonella spp. can be inhibited in ground beef through the addition of certain lactic acid-producing bacteria (lab; lactobacillus acidophilus np51, lactobacillus crispatus np35, pediococcus acidilactici, and lactococcus lactis ssp. lactis). this study evaluated the effects of lab inclusion on the organoleptic and biochemical properties typically associated with spoilage in traditionally packaged ground beef displayed at abusive ...	2011	22064744
lactobacillus fermentum cect 5716 is safe and well tolerated in infants of 1-6 months of age: a randomized controlled trial.	the objective of the study was to evaluate the safety and tolerance of an infant formula supplemented with lactobacillus fermentum cect5716, a probiotic strain isolated from breast milk, in infants of 1-6 months of age. a randomized double blinded controlled study including healthy infants was conducted. one month aged infants received a prebiotic infant formula supplemented with l. fermentum (experimental group) or the same formula without the probiotic strain (control group) for 5 months. the ...	2011	22155106
Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12® and Lactobacillus paracasei ssp. paracasei, L. casei 431® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study.	The present study investigated the ability of Bifidobacterium animalis ssp. lactis (BB-12®) and Lactobacillus paracasei ssp. paracasei (L. casei 431®) to modulate the immune system using a vaccination model in healthy subjects. A randomised, double-blind, placebo-controlled, parallel-group study was conducted in 211 subjects (56 % females, mean age 33·2 (sd 13·1) years). Subjects consumed a minimum of 109 colony-forming units of BB-12® (capsule) or L. casei 431® (dairy drink) or a matching place ...	2011	21899798
In vitro analysis of the bactericidal activity of Escherichia coli Nissle 1917 against pediatric uropathogens.	The usefulness of prophylactic antibiotics to prevent recurrent urinary tract infections in children was recently questioned. Some groups have attempted to use probiotics, most commonly lactobacillus, to prevent recurrent infections by altering the intestinal bacterial reservoir with variable results. Mutaflor® is a possible alternative probiotic in which the active agent is Nissle 1917. Nissle 1917 is a commensal Escherichia coli strain that eradicates pathogenic bacteria from the gastrointesti ...	2011	21855931
randomised clinical trial: the effectiveness of lactobacillus reuteri atcc 55730 rectal enema in children with active distal ulcerative colitis.	background intestinal microbiota manipulation, one of the pathogenetic components of inflammatory bowel disease (ibd), has become an attractive therapy for ulcerative colitis (uc). aim to assess in children with active distal uc the effectiveness of lactobacillus (l) reuteri atcc 55730 enema on inflammation and cytokine expression of rectal mucosa. methods a total of 40 patients (median age: 7.2 years range 6-18) with mild to moderate uc were enrolled in a prospective, randomised, placebo-con ...	2011	22150569
a 'bacteriocin pcr array' for identification of bacteriocin-related structural genes in lactic acid bacteria.	bacteriocins have been identified in many strains of lactic acid bacteria (lab) which are a source of natural food preservatives and microbial inhibitors. our objectives were to use a pcr array of primers to identify bacteriocin structural genes in bac(+) lab. dna sequence homology at the 5'- and 3'-ends of the various structural genes indicated that non-specific priming may allow pcr amplification of heterologous bacteriocin genes. successful amplification was obtained by real-time pcr and conf ...	2011	22119852
Identification and characterization of Lactobacillus florum strains isolated from South African grape and wine samples.	A total of 213 strains of lactic acid bacteria were examined in this study. Among these, 30 strains previously isolated from South African grape and wine samples remained unidentified. The identification of these isolates was performed by BLAST and phylogenetic analyses of 16S rDNA gene sequences, which indicated that the isolates belonged to Lactobacillus florum. In this work, we also designed a discriminative species-specific primer FLOR targeting the 16S rDNA gene of Lb. florum. The validity ...	2011	22137250
Effect of oxygen and temperature on the dynamic of the dominant bacterial populations of pig manure and on the persistence of pig-associated genetic markers, assessed in river water microcosms.	The aim is to evaluate the dynamic of Bacteroides-Prevotella and Bacillus-Streptococcus-Lactobacillus populations originating from pig manure and the persistence of pig-associated markers belonging to these groups according to temperature and oxygen.	2011	21854514
lactic acid bacteria enriched from human gastric biopsies.	the purpose of this paper was to check if viable bacteria, in particular lactic acid bacteria (lab), could be enriched from biopsies obtained from healthy gastroscopy patients. gastric biopsies were obtained from 13 gastroscopy patients and subjected to an anaerobic or microaerophilic enrichment procedure utilizing the portable microbe enrichment unit (pmeu). profuse microbial growth was observed in most cases. samples plated on mrs showed high numbers of lab. the most common species characteriz ...	2011	21991494
The role of copper in the manufacture of Finnish Emmental cheese.	The effects of added copper in the manufacture of Finnish Emmental cheese were studied. Consequently, cheeses were produced with or without the copper supplement and a facultative heterofermentative strain, Lactobacillus rhamnosus Lc705, which is currently utilized as a protective culture in large-scale manufacture in Finland. Cheeses were examined at 1, 7, 30, 60, and 90 d from the microbiological, chemical, and sensory points of view. Organic acid production was affected by the presence of cop ...	2011	21943734
Demonstration of vaginal colonization with GusA-expressing Lactobacillus jensenii following oral delivery in rhesus macaques.	The vaginal microbiome, which harbors beneficial Lactobacillus strains, is believed to be a major host defense mechanism for preventing infections of the urogenital tract. It has been suggested that the gastrointestinal tract serves as a reservoir for lactobacilli that colonize the vagina. Using rhesus macaques, we examined whether oral delivery of human vaginal Lactobacillus jensenii 1153-1646, a GusA-producing strain, would result in colonization of the rectum and the vagina. Lactobacilli were ...	2011	21907793
macrolide resistance and in vitro selection of resistance to antibiotics in lactobacillus isolates.	spreading of resistance to antibiotics is of great concern due to the increasing rate of isolation of multiresistant pathogens. since commensal bacteria may transfer determinants of resistance to pathogens, studies on development of resistance should include also lactobacilli. resistance to macrolides, penicillins and tetracycline was determined in 40 isolates of lactobacillus acidophilus, lactobacillus plantarum, lactobacillus crispatus, and lactobacillus casei isolated from faeces of apparentl ...	2011	21887650
preliminary x-ray analysis of twinned crystals of the q88y25_lacpl esterase from lactobacillus plantarum wcfs1.	q88y25_lacpl is an esterase produced by the lactic acid bacterium lactobacillus plantarum wcfs1 that shows amino-acid sequence similarity to carboxylesterases from the hormone-sensitive lipase family, in particular the afest esterase from the archaeon archaeoglobus fulgidus and the hyperthermophilic esterase estei isolated from a metagenomic library. n-terminally his(6)-tagged q88y25_lacpl has been overexpressed in escherichia coli bl21 (de3) cells, purified and crystallized at 291 k using the h ...	2011	22102251
Comparative in vitro evaluation of efficacy of mouthrinses against Streptococcus mutans, Lactobacilli and Candida albicans.	The present study was undertaken to compare the relative antimicrobial efficacy of two commercially available mouthrinses, Hexidine (0.12% chlorhexidine mouthrinse) and S-Flo (0.2% sodium fluoride), and a laboratory-manufactured propolis mouthrinse (10%) tincture with a dilution of 1:5 with water and their combinations against Streptococcus mutans, lactobacilli and Candida albicans.	2011	22068182
the immunomodulatory properties of viable lactobacillus salivarius ssp. salivarius cect5713 are not restricted to the large intestine.	purpose: the aim of this study was to better characterise the biological effects of lactobacillus salivarius ssp. salivarius cect5713, a probiotic with immunomodulatory properties. methods: live or dead probiotic was assayed in the tnbs model of rat colitis to determine whether viability was a requisite to exert the beneficial effects. in vitro studies were also performed in caco-2 cells to evaluate its effects on epithelial cell recovery and il-8 production. finally, the probiotic was assayed i ...	2011	21688122
Early colonization with a group of lactobacilli decreases the risk for allergy at five years of age despite allergic heredity.	Microbial deprivation early in life can potentially influence immune mediated disease development such as allergy. The aims of this study were to investigate the influence of parental allergy on the infant gut colonization and associations between infant gut microbiota and allergic disease at five years of age.	2011	21829685
the effect of probiotics on faecal microbiota and genotoxic activity of faecal water in patients with atopic dermatitis: a randomized, placebo-controlled study.	background: colonic microbiota is involved in the etiology of colon cancer according to several reports. studies also indicate that the microbiota differs between atopic patients and healthy subjects. objective: to evaluate whether a probiotic mix containing lactobacillus paracasei lpc-37, lactobacillus acidophilus 74-2, and bifidobacterium animalis subsp. lactis dgcc 420 can affect the microbiota and its genotoxic activity in healthy subjects and patients with atopic dermatitis (ad). methods: a ...	2011	21963389
the lactic acid bacteria and yeast microbiota of nineteen sourdoughs used for the manufacture of traditional/typical italian breads: interactions between ingredients and microbial species diversity.	the study of the microbiota of 19 italian sourdoughs used for the manufacture of traditional/typical breads allowed to identify, through a culture-dependent approach, 20 and 4 species of lactic acid bacteria (lab) and yeasts, respectively. numerically, the most frequent lab isolates were lactobacillus sanfranciscensis (ca. 28% of the total lab isolates), lactobacillus plantarum (ca. 16%) and lactobacillus paralimentarius (ca. 14%). saccharomyces cerevisiae was identified in 16 sourdoughs. candid ...	2011	22156414
effects and action mechanisms of berberine and rhizoma coptidis on gut microbes and obesity in high-fat diet-fed c57bl/6j mice.	gut microbes play important roles in regulating fat storage and metabolism. rhizoma coptidis (rc) and its main active compound, berberine, have either antimicrobial or anti-obesity activities. in the present study, we hypothesize that rc exerts anti-obesity effects that are likely mediated by mechanisms of regulating gut microbes and berberine may be a key compound of rc. gut microbes and glucose and lipid metabolism in high-fat diet-fed c57bl/6j (hfd) mice in vivo are investigated after rc and ...	2011	21915347
lc-ms/ms quantification of bioactive angiotensin i-converting enzyme inhibitory peptides in rye malt sourdoughs.	this study quantified antiotensin i-converting enzyme (ace) inhibitory peptides in rye malt sourdoughs supplemented with gluten proteins and fermented with six strains of lactobacillus spp. bioinformatic analysis of prolamins from barley, rye, and wheat demonstrated that the ace inhibitory peptides lqp, llp, vpp, and ipp are frequently encrypted in their primary sequence. these tripeptides were quantified by liquid chromatography-tandem mass spectrometry. tripeptide levels in sourdoughs were gen ...	2011	21985248
genome sequence of lactobacillus salivarius gj-24, a probiotic strain isolated from healthy adult intestine.	the draft genome sequence of lactobacillus salivarius gj-24 isolated from the feces of healthy adults was determined. its properties, including milk fermentation activity and bacteriocin production, suggest its potential uses as a probiotic lactic acid bacterium and start culture for dairy products.	2011	21742893