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listeriosis in an adult female chimpanzee (pan troglodytes). 19826818256
[method of controlling live vaccines against listeriosis].used was anton's conjunctival test with guinea pigs to control the actual immunogenicity and innocuity of a live vaccine against listeriosis. it was found that local immunity could be produced following a successive conjunctival infection only, initially with the use of a listeriosis vaccine and in not less than ten days later with pathogenic strains of the respective serotype. the method makes it possible to carry out both titration and control on the equal volume ratio of the vaccinal strains ...19826818755
monocyte production and kinetics in response to listeriosis in resistant and susceptible murine hosts. 19826818842
symbiotic relationships between macrophages and lymphocytes. 19826818844
regulation of macrophage ia expression in vivo and in vitro. 19826818848
automated identification of gram-positive bacteria.a total of 451 strains of gram-positive bacteria were identified with a prototype of the gram-positive identification card used in conjunction with the automicrobic system (vitek systems, inc., hazelwood, mo.). of the species that the gram-positive identification card is capable of identifying, 85% of staphylococcal, 50% of beta-hemolytic group a, b, c, f, and g streptococcal, 91% of group d streptococcal, 100% of pneumococcal, 63% of viridans streptococcal, and 100% of listeria monocytogenes st ...19826819308
genetic control of cell-mediated immunity in the rat. iii. t cells restricted by the rt1.a locus recognize viable listeria but not isolated bacterial antigens.this study investigates the discordance between the restriction criteria required for the transfer of cellular resistance to listeria monocytogenes (lm) and those for the transfer of delayed type hypersensitivity to listeria antigens. infective bacteria elicit both rt1.a-restricted t cells and rt1.b-restricted t cells. both populations of t cells mediate lymphoblast localization and macrophage accumulation, which are reactions characteristic of delayed type hypersensitivity (dth), and cause macr ...19826819320
kinetics of killing listeria monocytogenes by macrophages: correlation of 3h-dna release from labeled bacteria and changes in numbers of viable organisms by mathematical model.conventional methods of assessing antibacterial activities of macrophages by viable counting are limited by the precision of the statistics and are difficult to interpret quantitatively because of unrestrained extracellular growth of bacteria. an alternative technique based on the release of radioactive dna from labeled bacteria has been offered as overcoming these drawbacks. to assess it for use with macrophages i have made a correlation with the conventional viable counting method using a math ...19826819359
vitamin and nitrogen base requirements for listeria monocytogenes and haemolysin production.a complete chemically defined medium is described for the growth of different serovars of listeria monocytogenes. the medium supported rapid, luxuriant and transferable growth. at the same time haemolysin production was induced to the same extent as in tryptose phosphate broth. riboflavin and calcium-pantothenate were essential for the growth of all six strains tested. biotin, pyridoxal-hydrochloride and p-aminobenzoic acid were either essential or stimulatory to all strains. most strains did no ...19826819739
[swine alveolar macrophages: description and functional analysis].swine alveolar macrophages (sam) were characterized according to several properties: this spherical cell is able to adhere in vitro to plastic and glass substrata. its size varies from 10 to 20 mu; on the cytochemistry level, up to 85% sam appear to be peroxidase-negative, whereas they are all esterase-positive. the sam phagocytic capacities were investigated by using three different substrata: zymosan, chicken red blood cells and listeria monocytogenes. sam were also characterized by their "acc ...19826819804
immunosuppression, nonspecific b-cell activation, and mitogenic activity associated with a high molecular weight component from listeria monocytogenes.a high molecular component of a saline extract derived from listeria monocytogenes contained amino acids, carbohydrates, and phosphorus. the same fraction was capable of promoting both the in vitro mitogenic and adjuvant activities and the in vivo immunosuppressive activity displayed by the crude extract. the material was mitogenic to b but not to t lymphocytes in vitro. responses to sheep and horse erythrocytes as well as to lipopolysaccharide were suppressed. immunosuppression was dose depende ...19826820330
[analysis of protective mechanisms against infection by listeria monocytogenes. accumulation and activation of macrophages]. 19826820352
influence of some bacterial components on some mononuclear phagocyte system functions.the effects of listeria monocytogenes treatment on some functions of peritoneal macrophages in tumor-bearing rats were evaluated. in particular phagocytosis and intracellular killing of escherichia coli and candida albicans and chemotactic response to activated serum were studied in untreated and treated animals. different restoration of macrophage functions, depressed in tumor-bearing rats, was obtained by treatment with whole formolinated l. monocytogenes or its crude extract.19826821337
effects of erythromycin in combination with penicillin, ampicillin, or gentamicin on the growth of listeria monocytogenes.since the optimal antimicrobial therapy for infections caused by listeria monocytogenes, particularly in patients allergic to penicillin, is uncertain, we investigated the in vitro effects of erythromycin, alone and in combination with other antibiotics, on listeriae. seven strains of listeriae were inhibited but not killed by erythromycin, penicillin g, or ampicillin when tested by a microtiter broth dilution method. susceptibility to gentamicin decreased when tryptose phosphate broth was subst ...19826821458
immunopathology of bcg infection in genetically resistant and susceptible mouse strains.natural resistance to mycobacterium bovis (bcg) is under the control of a single gene, designated bcg. resistant (bcgr) mice prevent multiplication of an i.v. injected inoculum of congruent to 10(4) dispersed bcg cells, whereas progressive multiplication of this pathogen occurs in the first 3 wk of infection in spleens and livers of susceptible (bcgs) mice. striking differences in the development of cellular immunity, as measured by granuloma formation in the liver and spleen, delayed-typed hype ...19826749986
listeriosis in renal transplant recipients: report of an outbreak and review of 102 cases.we observed six renal transplant recipients with listeriosis during a 10-week period in the autumn of 1979. investigation of this outbreak established that the first four cases wer close contacts, all infected by listeria monocytogenes serotype 1b. the source of infection and route of spread were not identified. a total of 102 renal transplant recipients with listeriosis have now been reported. the major manifestation of disease was meningitis in 50% of the patients, parenchymal disease of the c ...19826750737
listeria monocytogenes abscess in the basal ganglia. 19826752348
fate of listeria monocytogenes in murine peritoneal macrophage subpopulations.peritoneal macrophages derived from cd-1 and c57bl/6 mice were separated into distinct groups based on their buoyant densities on discontinuous gradients of percoll and assayed for antibacterial activity against listeria monocytogenes. subpopulations of peritoneal macrophages derived from listeria-immune mice present a wide variation in their ability to control intracellular infection. distinct subsets were found which exhibited bacteriostatic and listericidal activity. the fractionation procedu ...19826797945
decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to t cells.this paper describes the effects of two lysosomotropic compounds, ammonia and chloroquine, on the interaction of mononuclear phagocytes with immune t cells. the uptake and ingestion of listeria monocytogenes by macrophages were not affected by the drugs; however, the macrophage catabolism of 125i-labeled listeria was reduced in a dose-dependent way. the macrophage presentation of listeria to t cells, an i-region-dependent phenomenon, was also inhibited. the degree of inhibition of catabolism par ...19826798568
enhanced adoptive transfer of immunity to listeria monocytogenes after in vitro culture of murine spleen cells with concanavalin a.in vitro incubation of spleen cells with t-cell mitogens has been shown to augment cytotoxic and cytolytic t-cell function. the plant lectins concanavalin a and phytohemagglutinin were employed in a similar fashion to investigate their abilities to enhance cell-mediated immunity to the microbial pathogen listeria monocytogenes. spleen cells from immune mice were incubated in vitro with concanavalin a or phytohemagglutinin before passive transfer into normal recipients. results indicated a 10- to ...19826799407
[modes of the formation of elementary bodies and their isolation from the cell in l-form bacteria].elementary bodies are formed on the cell surface and inside the cell body in all cell types characteristic of l-form cultures, i. e. spherical cells, large bodies and filament structures. the following ways of elementary body formation are described: by budding on the cell surface, appearance immediately in the cytoplasm, in the vacuole, as a result of cytoplasmic fragmentation accompanied by the lysis of the cell, as well as in cases of the separation of cytoplasmic areas surrounded by the memb ...19826805173
stimulation of monocyte production by an endogenous mediator induced by a component from listeria monocytogenes.a monocytosis-producing activity (mpa) is present in a saline-extractable material (se) from listeria monocytogenes. the mechanism of stimulation of monocyte production by se was studied. serum obtained from mice at appropriate times after injection of se induced monocytosis in normal recipients. the monocytosis-inducing activity present in serum differed from se with respect to timing of the monocytosis, fractionation pattern on a sephadex g-200 column, and thermolability. the minimum dose of s ...19826806176
listeria meningitis in an immunocompetent child.we report a case of listeria monocytogenes meningitis in an apparently healthy 3-year-old boy. this is the first case reported in english literature where adequate evaluation of immune status did not reveal an immunologic defect. the patient is in the age group least affected by an opportunistic organism and has been living in a district known for a high incidence of listeria in livestock. the epidemiologic implication of this observation is discussed.19826889588
listeriosis in a neonate and the mother.listeria meningitis developed in a two-day-old child whose mother harboured listeria monocytogenes of the same serotype 4 in her vagina. child and mother were both effectively treated with ampicillin. this is the first report of confirmed neonatal listeriosis from nigeria.19826805108
[acquired resistance to facultative intracellular bacteria: as to the identity of the cell mediating protection and delayed hypersensitivity (author's transl)].acquired resistance to facultative intracellular bacteria depends on two interacting classes of cells: antigen specific t lymphocytes and mononuclear phagocytes. after specific interaction with antigen, t lymphocytes are capable of activating mononuclear phagocytes to form granulomas and to acquire enhanced bacteriocidal capacity. in general, protection is paralleled by delayed hypersensitivity to bacterial antigens. although robert koch had already postulated that protection against mycobacteri ...19826805155
non-h-2 restriction of expression of passively transferred delayed sensitivity.the results of this study of allogeneic restriction of passively transferred delayed sensitivity to listeria antigens serve to illustrate the complexity of in vivo models. they show that the h-2 restriction observed when delayed-type hypersensitivity was transferred between h-2-congenic strains was no more severe than the restriction observed when delayed-type hypersensitivity was transferred between parental and f1 mice and between different strains sharing the same h-2 haplotype. it is obvious ...19826802925
ontogeny of murine macrophages: functions related to antigen presentation.macrophage function in neonates was dissected into four components: antigen uptake and catabolism, cytotoxicity, antigen presentation, and the production of the lymphostimulatory molecule interleukin-1 (also called thymocyte mitogenic protein or lymphocyte-activating factor). the uptake and catabolism of 125i-labeled listeria monocytogenes was equivalent in macrophages from adult and neonatal mice. however, interactions between macrophages from neonates, heat-killed listeria organisms, and immun ...19826804386
direct correlation between delayed footpad reaction and resistance to local bacterial infection.the resistance to bacteria was studied at the site of delayed footpad reaction in mice immunized with listeria monocytogenes. when a challenge injection of listeria was given into the footpad of immune mice, no enhancement of bacterial elimination was observed before the generation of delayed footpad reactivity. after the generation of delayed reactivity, an enhanced elimination of listeria or salmonella typhimurium was observed only at the site of strongly positive delayed footpad reaction elic ...19826804395
routine test for in vitro differentiation of pathogenic and apathogenic listeria monocytogenes strains.the exosubstance of rhodococcus equi in a prepurified form strongly enhanced the hemolytic effect of certain strains of listeria monocytogenes. the strains which produced positive synergic hemolysis with this exosubstance were also pathogenic for guinea pigs and white mice. the other strains, which remained nonhemolytic in the presence of the r. equi. exosubstance, were apathogenic for those animals. a routine test was devised for the in vitro determination of the pathogenicity of l. monocytogen ...19826804488
regulation of macrophage populations. iv. modulation of ia expression in bone marrow-derived macrophages.the expression of i region-associated (ia) antigens was studied in macrophages derived from bone marrow cell precursors cultured in l cell-conditioned medium (lcm) as a selective growth stimulator. very few macrophages expressed ia either while growing actively in lcm or when quiescent, after the removal of lcm from the culture. the addition of t cell lymphokines, however, stimulated the biosynthesis and membrane expression of ia. uptake of bacteria by the macrophage during exposure to the lymph ...19826801119
listeria monocytogenes meningitis and decreased phagocytosis associated with iron overload.a patient with listeria monocytogenes meningitis was found to have idiopathic haemochromatosis and monocytes with reduced phagocytic capacity. the phagocytic function recovered completely after a series of therapeutic phlebotomies. in-vitro iron had a deleterious effect on the phagocytic capacity of monocytes and granulocytes. these findings show that iron overload in the host can increase susceptibility to l monocytogenes infection not only by increasing the virulence of the organism but also b ...19826800535
alteration of cell-mediated immunity to listeria monocytogenes in protein-malnourished mice treated with thymosin fraction v.cell-mediated immune reactivity, measured by lymphocyte responsiveness to phytohemagglutinin, was higher in both young or aged mice fed a 4% casein diet compared with age-matched controls. treatment in vivo with bovine thymosin fraction v decreased the responsiveness to phytohemagglutinin of lymphocytes from mice fed either the control or moderately protein-deficient diets when compared with mice treated in vivo with saline. resistance against listeria monocytogenes, known to be a cell-mediated ...19826981605
mechanism of depletion of t lymphocytes from the spleen of mice infected with listeria monocytogenes.marked changes in the splenic lymphocyte populations during murine infection with listeria monocytogenes were observed histologically and quantitated by the immunofluorescence of thy-1+ immunoglobulin (ig-) (t) and ig+ (b) cells. cells were depleted from the t-dependent areas of the spleen, and the number of t cells in suspensions prepared from spleens of mice 1 to 3 days after primary or secondary infection were less than 1/10 of normal. high numbers of alcohol-killed listeria sp. did not cause ...19826982869
recovery from t cell depletion during murine listeriosis and effect on a t-dependent antibody response.during the infection of mice with listeria monocytogenes, there is a profound depletion of t (thy-1+ ig-) lymphocytes between days 1 and 4, followed by an increase in t cells to three times normal levels by day 9. the recovery of t cell numbers required cell proliferation, being sensitive to vinblastin and cyclophosphamide. adult thymectomy 6 months before infection had no effect on recovery. the repopulating cells were no more sensitive than normal t cells to hydrocortisone. b lymphocytes (ig+ ...19826982870
age-dependent differences in outcome of infections, with special reference to experiments in mice.the host defects that increase either the frequency or the severity of certain infections in older persons are reviewed briefly. the major defect is in the functioning of the lymphocyte-macrophage system; this is expressed as deficits in cutaneous reactivity and t cell response after antigenic stimulation. a review of induced infections in experimental animals shows results generally consistent with the data in humans. infections due to listeria monocytogenes, salmonella typhimurium, and toxopla ...19826982911
dose-dependent effect of glucocorticosteroids on pulmonary defenses in a steroid-resistant host.an experimental model of listeria monocytogenes pneumonia was employed in order to study the pathogenesis of lung infection with a facultative intracellular pathogen in normal and steroid-treated hosts. guinea pigs, which resemble humans as a "steroid-resistant" species, were treated with week-long regimens of cortisone acetate or saline. cortisone regimens were 100 mg/kg/day (low-dose) or 200 mg/kg/day (high-dose). lungs were then infected with listeria monocytogenes, and groups were compared f ...19826983845
activation of macrophages by products of lymphocytes from normal and syphilitic rabbits.the production of soluble macrophage-activating factors by lymphocytes from syphilitic and normal rabbits was examined. culture supernatants of splenic lymphocytes cultured with treponema pallidum antigens or concanavalin a were incubated with rabbit peritoneal macrophages in vitro. the macrophage monolayers were then washed and infected with log-phase listeria monocytogenes. activation of the macrophages by lymphocyte products was measured by the ability of the macrophages to resist intracellul ...19827049954
application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals.model systems to study the effects of chemicals of environmental concern on bacterial and parasitic diseases as well as the immunosurveillance and destruction of transplantable tumor cells were described and evaluated. studies were conducted in female b6c3f1 mice following adult or pre/postnatal exposure to several prototype chemicals. the prototype chemicals employed included the synthetic estrogen diethylstilbestrol (des), the polycyclic aromatic hydrocarbon benzo(a)pyrene (b[a]p), and the car ...19827060548
simple screening method for gram-positive bacterial beta-lactam antibiotic tolerance on routine laboratory bauer-kirby antibiogram plates.a simple screening method served to detect beta-lactam antibiotic-tolerant variants of clinical isolates and laboratory control strains of staphylococcus aureus, s. epidermis, group b beta-hemolytic streptococci, and listeria monocytogenes. the beta-lactamase(s) of a multiple drug-resistant strain of enterobacter cloacae (isolate no. 19) yielded most consistent results as compared with several other beta-lactamase producers; the e. cloacae beta-lactamase(s) was neutralized by clavulanic acid. sp ...19827075323
[protective mechanisms against listeria monocytogenes in aged mice (author's transl)]. 19827076103
dietary stress and development of resistance ot listeria monocytogenes in mice.the native and acquired cell-mediated immune resistance against listeria monocytogenes steadily developed in young mice after weaning and reached maximum activity at 6 and 12 weeks of age, respectively. mice fed a high fat (20% corn oil) diet from 3 weeks of age had a significantly more rapid development of resistance against l. monocytogenes. mice fed the high fat diet beginning at 6 and 12 weeks of age had significantly lower native preimmune resistance against l. monocytogenes after 3 weeks o ...19827097360
elevation of natural killer activity and nonspecific immunity following injection of listeria cell walls.mice given a single intraperitoneal injection of cell walls from listeria monocytogenes (lcw) prior to challenge with candida albicans or a mammary carcinoma showed significantly increased survival compared to saline injected controls. the cell walls were mitogenic for spleen cells in vitro. levels of stimulation were lower than for con a and pha but comparable to those induced by lps. peritoneal exudative cells, but not spleen cells, harvested from mice injected with lcw showed significant elev ...19827109968
two steps in the generation of acquired cellular resistance against listeria monocytogenes: accumulation and activation of macrophages.mice were immunized with 1 x 10(3) viable listeria monocytogenes, and the mechanism of the acquired resistance against challenge infection with 5 x 10(4) l. monocytogenes was studied by the use of the peritoneal cavity of mice as the site of challenge. an enhanced elimination of bacteria from the peritoneal cavity became detectable on day 5 after immunization, and lasted thereafter. before day 10 postimmunization, a marked accumulation of macrophages was observed after the challenge but the in v ...19827118166
[recovery from from listeria monocytogenes meningitis in an adult].the authors describe a case of meningitis by listeria monocytogenes from which the patient, an adult suffering from a chronic lymphatic leukosis, recovered completely. both the immune-suppressor treatment and the basic lymphoproliferative disease may have given rise to this infective disease. the diagnosis has been obtained by isolating the germ in liquor-cultures. we want to point out the importance of a specific and early antibiotic treatment.19827121882
graft infection and bacteremia with listeria monocytogenes in a patient receiving hemodialysis.patients receiving hemodialysis are particularly susceptible to infection. we report a case of listeria monocytogenes bacteremia and graft infection developing in a patient receiving hemodialysis. vancomycin hydrochloride therapy was initiated in anticipation of a staphylococcal infection, and continued as the patient's clinical course improved. ultimately the arteriovenous graft required excision. identification of the organism and drug susceptibilities are described. to our knowledge, this is ...19827138165
antepartum treatment of listeria monocytogenes septicemia.maternal septicemia with listeria monocytogenes is becoming a more prevalent problem for those dealing with obstetric patients. a flu-like illness is often present in the mother prior to delivery of the infected infant. treatment regimens have included intravenous antibiotic therapy for the mother and induction of labor. the infant often dies of respiratory distress syndrome due to prematurity. data from the literature tend to support the concept of antepartum therapy without delivery, unless th ...19827146966
[listeria monocytogenes rhombencephalitis: clinical and pathologic-anatomic findings in a rare encephalitis form]. 19827155231
[diagnosis of listeriosis. value and limitations of the leukocyte migration inhibition test].a human leucocyte migration inhibition test (hlmt) was performed in 50 healthy subjects and in 23 patients with bacteriologically confirmed listeriosis, using listeria monocytogenes as antigen. considerable inhibition was found in most patients, whereas the test was negative in all controls. in view of this consistent relationship between test and disease, it is suggested that the hlmt could be used for the indirect diagnosis of listeriosis, taking into account the delay between the onset of inf ...19827155882
severe meningitis due to listeria monocytogenes. a review of 40 cases in adults.during a 10-yr period, 40 cases of severe listeria monocytogenes meningitis were observed. all patients showed consciousness disturbances and 27 of them (68%) focal neurologic signs. cranial nerve palsies were common (57%). early general seizures (13 patients) and presence of underlying disease (12 patients) were associated with a high mortality rate. although the management of antibiotic therapy is open for discussion, chloramphenicol (used in 7 patients) seems to be more effective than other d ...19827163778
[listeria monocytogenes. intrauterine listeria infection in 2 pregnant women]. 19827167952
listeria monocytogenes sepsis complicated by the adult respiratory distress syndrome. 19826961312
transfer of salmonella resistance and delayed hypersensitivity with murine-derived transfer factor.protective host immunity and delayed hypersensitivity were transferred to nonimmune icr and c3h/hej mice with transfer factor prepared from the splenic lymphocytes of icr swiss mice immune to salmonella typhimurium. only mice injected with the "immune" dialysate exhibited significant footpad swelling (p less than 0.01) to a spent medium antigen of s. typhimurium, but not listeria monocytogenes. host survival to a lethal salmonella challenge infection was seen only in transfer factor-injected mic ...19827042572
rapid differentiation of bacterial meningitides by direct gas-liquid chromatography.rapid identification of haemophilus influenzae and other bacillary meningitides was attempted by gas-liquid chromatography (glc) of the metabolic by-products in broth cultures and in cerebrospinal fluid (csf) samples obtained from experimental meningitis produced in new zealand white male rabbits. these results were correlated with the glc of csf of meningitis patients. a major peak with retention time of succinic acid was found in the broth cultures of all bacilli tested including h. influenzae ...19827042759
induction of acquired cellular resistance in mice with viable and macrophage-processed listeria monocytogenes.intracutaneous immunization of mice with 10(5) or 10(6) viable listeria resulted in acquired cellular resistance (acr) of short duration (7 days). the period during which viable listeria monocytogenes had to be present in order to induce acr was estimated by killing the listeria at different times after immunization by injecting the bactericidal antibiotic amoxycillin. the killing of listeria within 6 h after injection prevented the induction of a cr completely, between 6 and 12 h partially, whi ...198215861581
phagocytotic activity of monocytes from diabetic patients.the phagocytotic activity of monocytes from diabetic patients and healthy controls was studied. it was found that the number of phagocytizing cells from diabetic patients was significantly reduced in comparison with that from control individuals. however, the number of bacteria phagocytized per cell was similar in both groups. plasma from healthy controls added to diabetic monocytes did not cause any significant change in their phagocytotic capacity. addition of insulin to the plasma of diabetic ...19836443809
effect of quinonyl-n-acetyl muramyl dipeptide on immune responses in tumor-bearing mice.the efficacy of 6-o-qs-10-n-acetyl muramyl-l-valyl-d-isoglutamine methyl ester (quinonyl-mdp-66) for restoring impaired immune status was examined in mice bearing lewis lung carcinoma. quinonyl-mdp-66 suspended in phosphate-buffered saline was shown to restore the depressed allogeneic cell-mediated cytotoxicity of spleen cells from mice with lewis lung carcinoma when the chemical was injected twice intraperitoneally, intravenously, or intratumorally. however, primary tumor size and the numbers o ...19836822411
development of immunity against listeria monocytogenes in athymic nude versus neonatally thymectomized mice.the thymus requirement for the development of immunological responsiveness was determined by estimation of immune responses raised to listeria monocytogenes in athymic nude, neonatally thymectomized, and sham-operated mice at 6 weeks of age. not only sham-operated mice, but also neonatally thymectomized mice could completely eliminate the bacteria from the spleen and liver, while athymic nude mice could not eliminate them and showed a persistent form of infection. a strong delayed footpad reacti ...19836825182
production, purification, and properties of a bacteriocin from staphylococcus aureus isolated from saliva.staphylococci from samples of human saliva were isolated on staphylococcal-selective agar plates. these strains were tested for the inhibition of the growth of staphylococcus aureus fda209p. the frequency of inhibitory strains among all of the staphylococcal isolates was 5.2%. strain iys2, which formed the biggest inhibitory zone against the growth of the indicator strain, was used as the producer of bacteriocin. iys2 was identified to be s. aureus, based on its biological properties. the bacter ...19836832811
effect of micropolyspora faeni cells and cell wall fractions on rabbit alveolar macrophages.the reactivity of alveolar macrophages (am) to cells and cell wall fractions (cwf) of micropolyspora faeni was investigated. exposure of cultured am to m. faeni and its cwf caused the am to form clumps or aggregates which remained attached to the culture dish surface. other gram-positive and gram-negative bacteria as well as yeast, zymosan, latex microspheres, and isolated peptidoglycan from listeria monocytogenes did not cause this response. the response was independent of species source and an ...19836832824
effect of local and systemic macrophage activation in hamsters on infection with treponema pertenue and treponema pallidum bosnia a.the role of nonspecific macrophage activation in the destruction of treponemes needs to be defined. studies have been hindered by an inability to confirm that macrophages have enhanced bactericidal activity at the site of treponemal infection. we show that subcutaneous and intravenous vaccination with bcg (mycobacterium bovis) induces macrophage activation in hamsters, as determined by an enhanced ability to suppress the growth of listeria monocytogenes in the livers, spleens, and inguinal lymph ...19836834361
pleural-pulmonary aspects of listeria monocytogenes infection.the most common forms of listeria monocytogenes infection in adults are meningitis-encephalitis and sepsis. infection of the pulmonary parenchyma and pleura have rarely been reported. a case of listeria meningitis presenting with pleural space infection in an immunosuppressed patient is presented and a review of 5 additional patients with listeria infection of the respiratory tract is included. all 6 patients described in this report had l. monocytogenes infections presenting with respiratory tr ...19836836191
experimental allergic orchitis induced by unilateral intratesticular bacterial infection in guinea-pigs.inoculation of 1 x 10(3) viable listeria monocytogenes into unilateral testis induced pathological changes in the contralateral testis and epididymis in guinea-pigs. because l. monocytogenes was not detected in the contralateral testis, liver or spleen during the period of the experiment, that is, bacterial growth was limited to the inoculated site, the pathological changes in the contralateral testis may be due to autoimmune mechanisms, but not due to bacterial inflammation. the pathological ch ...19836840807
cryptogenic liver abscess due to listeria monocytogenes. 19836842032
ataxia in listeria monocytogenes infections of the central nervous system.from 1976 to 1981 listeria monocytogenes was second only to neisseria meningitidis as the cause of bacterial infections of the central nervous system in adults at our hospital. none of the patients with listeria infection was immunosuppressed or had an underlying malignancy. ataxia was an initial feature in five of the eight patients, and in three of them it persisted beyond their discharge from the hospital. ataxia was not a feature of the clinical picture of 14 other adult patients with mening ...19836844962
listeria monocytogenes endocarditis on a prosthetic heart valve.listeria monocytogenes endocarditis, an illness with a potentially high mortality developed in a patient with a porcine mitral valve heterograft. after treatment with parenteral ampicillin and streptomycin, blood cultures remained sterile and vegetations noted before treatment cleared. delay in diagnosis and institution of appropriate antimicrobial therapy may occur because of the diverse morphologic features of l monocytogenes.19836844978
listeria monocytogenes. an important pathogen in premature labor and intrauterine fetal sepsis.listeria monocytogenes is a rare complication of pregnancy. maternal listeriosis often causes premature labor and congenital infections. high perinatal morbidity and mortality rates are associated with this disease. two cases of fetal perinatal infections, complications and management are discussed.19836854552
increased risk of experimental central nervous system listeriosis in rats with chronic serum sickness. an immunohistopathological study.the incidence and severity of central nervous system (cns) infection were increased following the intraperitoneal innoculation of listeria monocytogenes in adult wistar rats with experimental chronic serum sickness. the results were attributed to an alteration in the blood-cerebrospinal fluid barrier induced by immune complex deposits in the choroid plexus of animals hyperimmunized with bovine serum albumin. cns inflammation occurred in 16 of 40 (40%) of the test animals studied; one of 36 (2.8% ...19836864235
prenatal diagnosis of congenital listeriosis.a case of congenital listeriosis presenting with premature labor at 24 weeks' gestation is described. listeria monocytogenes were isolated from the amniotic fluid, which also had an increased concentration of iga. the significance of amniotic fluid ig levels and their potential value in the diagnosis of intrauterine infections as an adjunct to the isolation of the infectious agent is discussed.19836869650
cellular immune response to marek's disease: listeriosis as a model of study.the immune response of chickens to listeria monocytogenes was studied as a potential model for cell-mediated immunocompetence. chickens genetically resistant and susceptible to marek's disease (md) did not differ in their ability to survive listeria, although during the early stages of infection the bacteria replicated more readily in md-susceptible chickens. md-susceptible chickens responded earlier than md-resistant chickens, and with equal or increased intensity, in assays of various componen ...19836870717
a tumor-associated lactic dehydrogenase virus suppresses the host resistance to infection with listeria monocytogenes.infection of mice with lactic dehydrogenase virus (ldv) causes a lifelong chronic infection which is followed by alterations in immune responses during the acute phase of the infection. ldv was found to impair many functions of the reticuloendothelial system and to suppress macrophage-dependent immune responses. we tested the effect of acute infection with ldv in mice on the macrophage-mediated resistance to infection with a virulent bacterium. we found that ldv reduces the host's capacity to re ...19836873999
[large listerial abscess of the brain stem. favorable effect of antibiotic therapy].a 52-year-old woman developed headache with fever followed after several days by a left hemiplegia, paralysis of the right iiird, vth, and viith cranial nerves, and a right cerebellar syndrome. the csf contained 48 white cells/mm3 and 0,80 g/l of proteins. blood and csf cultures were negative. in spite of an early massive antibiotic therapy, successive ct scans demonstrated the development of a voluminous rhombencephalic abscess. clinical improvement occurred only after 1 month of treatment. the ...19836878977
laboratory diagnosis of bacteremia by headspace gas-liquid chromatography.the growth of staphylococcus aureus, streptococcus pneumoniae, s. fecalis, s. sanguis, s. bovis, s. mitior, s. agalactiae, escherichia coli, a-d group, klebsiella aerogenes, k. oxytoca, enterobacter cloacae, proteus mirabilis, serratia marcescens, pasteurella multocida or listeria monocytogenes in 83 blood cultures was detected in a 1.5-min analysis using head-space gas-liquid chromatography. two hundred and twenty-four blood cultures in which there was no growth of micro-organisms were negative ...19836888963
effective antibacterial protection induced by a listeria monocytogenes-specific t cell clone and its lymphokines.the capacity of the murine listeria monocytogenes-specific t cell clone 9-36-1 and of lymphokines derived therefrom to induce antibacterial protection in vivo was studied. clone 9-36-1 was stimulated to proliferate and to produce lymphokines by in vitro culture with syngeneic accessory cells and heat-killed l. monocytogenes. although 9-36-1 cells were highly active in vitro, intravenous transfer of the cells resulted in marginal protection against a systemic infection with l. monocytogenes. in c ...19836220971
the immune response. 19836224323
in vitro activity of teichomycin compared with those of other antibiotics.the glycopeptide antibiotic teichomycin had in vitro activity comparable to that of vancomycin against most gram-positive species, and it inhibited methicillin-resistant staphylococcus aureus and staphylococcus epidermidis. it was twofold more active against many s. aureus and s. epidermidis isolates than was vancomycin. teichomycin had activity comparable to that of vancomycin against listeria monocytogenes and streptococcus faecalis. it was generally more active against streptococci than was v ...19836227282
in vitro activity of ciprofloxacin (bay o 9867).the in vitro activities of ciprofloxacin (bay o 9867) and seven comparative antimicrobial agents against 664 aerobic and facultatively anaerobic bacterial isolates were studied. minimal inhibitory concentrations (mics) of ciprofloxacin were less than or equal to 2 micrograms/ml for enterobacteriaceae, less than or equal to 8 micrograms/ml for nonfermentative gram-negative bacilli, less than or equal to 4 micrograms/ml for gram-positive cocci, less than or equal to 0.03 micrograms/ml for aeromona ...19836228192
interference of pseudomonas aeruginosa with immunospecific host defenses.pseudomonas aeruginosa, an important nosocomial pathogen, has numerous virulence factors that may interfere with unspecific host defense mechanisms (complement components, neutrophils, macrophages). furthermore, pseudomonas aeruginosa or substances derived from it can inhibit lymphocyte proliferative responses and alter immune responses, especially cell-mediated immune responses as evidenced by prolonged survival of skin homografts and suppression of dth skin reaction in humans and laboratory an ...19836232960
peritoneal exudation of macrophages by irritants and its effect on immune responses against sheep erythrocytes and listeria monocytogenes.relation between the degradation of antigenic substances by peritoneal exudate macrophages induced by different irritants and subsequent induction of immune responses against srbc or listeria monocytogenes were studied. delayed footpad reaction and antibody production to srbc were both suppressed by pretreatment with thioglycollate or with killed corynebacterium parvum. in contrast, delayed footpad reaction and acquired cellular resistance to listeria were augmented by pretreatment with thioglyc ...19836420589
[rapid diagnosis of purulent meningitis].the cerebrospinal fluid of 589 subjects, 78 of whom were suffering from a purulent meningitis were examined. comparatively by classical bacteriological techniques (direct examination and culture) and by electro-immunodiffusion, latex agglutination, and limulus endotoxin assay. soluble bacterial haemophilus influenzae type b, neisseria meningitidis group a, c, and streptococcus pneumoniae antigens, were tested by electro-immunodiffusion and latex agglutination, and soluble bacterial n. meningitid ...19836421209
hydrogen peroxide-mediated antagonism against serratia marcescens by streptococcus mitis.the alpha-hemolytic streptococcus mitis strain no. 17-1, isolated from the oral cavity of an healthy female adult, antagonized the growth of all 24 test strains of serratia marcescens examined; furthermore, this strain inhibited the growth of various strains of staphylococcus aureus, s. epidermidis, streptococcus pyogenes, s. agalactiae, s. pneumoniae, haemophilus influenzae, listeria monocytogenes, and corynebacterium diphtheriae. however, strans of escherichia coli, enterobacter cloacae, klebs ...19836372321
bacteriologic and epidemiologic studies on the occurrence of listeria monocytogenes in healthy cattles.the incidence of listeria monocytogenes in 61 fresh stool specimens from normal beef cattle obtained from a slaughterhouse in rio de janeiro was studied. the animals were divided in two groups of similar number separated by age; animals of up to five years, and animals of 5 years and more. in the research of this microorganism 9 culture media were used: four enrichment media, one for transport and four selective media. from the results, 11 animals proved to be carriers, of which nine were five y ...19836424357
functional studies on mouse macrophages activated by phospholipids from listeria monocytogenes and aspergillus fumigatus.the administration of phospholipids from listeria monocytogenes and aspergillus fumigatus to mice resulted in the development of macrophages with increased functional activity. it has been found that stimulated macrophages have increased phagocytic activity, enhanced chemotactic reactivity and augmented adherence to plastic surface. the activity of fcig macrophages and complement receptors as well as the rate of the recovery of the fcig receptors after phagocytosis were significantly higher in a ...19836422902
[isolation of listeria monocytogenes from organs of young lambs].samples of organs from 50 lambs, 3-45 days old, brought to this laboratory from 44 different flocks for post mortem examination, were examined for listeria monocytogenes. various diseases were found as cause of the death. the bacterium was isolated from 3 lambs (6%) which had died from e. coli-septicaemia. two of these lambs were 3 days old whereas the third was 23 days.19836424092
immunostimulatory mouse granuloma protein.earlier studies have shown that from subcutaneous talc-induced granuloma in mice, a fraction could be extracted that fully protected mice against listeria monocytogenes. using standard biochemical procedures--i.e., ammonium sulfate fractionation, preparative electrophoresis, gel filtration chromatography, isoelectric focusing, and preparative polyacrylamide gel electrophoresis--we have now purified an active factor to homogeneity. a single band was obtained in nadodso4/polyacrylamide gel with an ...19836578514
immunoregulation by macrophages ii. separation of mouse peritoneal macrophages having tumoricidal and bactericidal activities and those secreting pge and interleukin i.macrophage subpopulations having bactericidal or tumoricidal activities and secreting interleukin i (il1) or prostaglandin e (pge) were identified through primary or secondary infection with salmonella enteritidis and separated by sedimentation velocity. bactericidal activity was measured by [3h]-thymidine release from listeria monocytogenes and tumoricidal activity by 51cr-release from c-4 fibrosarcoma or p815 mastocytoma cells. macrophages with bactericidal activity were distinguished from tho ...19836602218
the role of macrophages in acquired cell-mediated immunity to toxoplasma gondii.mice immunized by primary infection with an avirulent strain of toxoplasma gondii were protected against challenge infection with a highly virulent strain, even though macrophages were eliminated either by dextran sulfate or by carbon ink. this findings differs strikingly from previous results obtained in similar experiments with other intracellular pathogens such as listeria monocytogenes and salmonella typhimurium. it is therefore concluded that the macrophage population, which plays an essent ...19836602268
models of t cell deficiency in listeriosis: the effects of cortisone and cyclosporin a on normal and nude balb/c mice.it is often difficult to test the role of t lymphocytes in resistance to infection because most models of t cell deficiency are associated with altered nonspecific resistance. in an attempt to address this problem, we compared the effects of cyclosporin a (cya), cortisone (ca), and the athymic state on the course of murine listeriosis. we chose listeriosis because resistance to listeria monocytogenes occurs in two phases. bacterial multiplication is controlled by nonspecific defense mechanisms i ...19836602835
haemophilus influenzae in genitourinary tract infections.haemophilus influenzae was isolated in pure or predominant culture from genital specimens from nine females and two males. four of the females had vaginitis, two had iud-related endometritis, one had an incomplete septic abortion, and one had probable urethral syndrome. two males had urethritis.19836608436
listeriosis as a cause of maternal death: an obstetric complication of the acquired immunodeficiency syndrome (aids).a case of maternal death due to listeria monocytogenes bacteremia, with survival of the prematurely delivered infant, is presented. lymphopenia and a haitian origin suggest that the fatal outcome was related to the acquired immunodeficiency syndrome (aids). to our knowledge, this is the first recorded instance of a maternal death due to listeriosis.19836614087
fatal infection in mice after injection of immunosuppressive serum fractions from surgical patients.following surgical or accidental trauma many patients show suppression of cellular immunity. in this investigation sera from severely burned patients and patients undergoing aortic aneurysm repair were studied. sera shown to suppress phytohaemagglutinin-induced blastogenesis of normal human lymphocytes were fractionated using ion exchange and g25 sephadex chromatography. suppressive activity was largely confined to a low molecular weight (lmw) fraction and was dose dependent. lmw fractions of no ...19836616163
the effect of diethylstilbestrol as measured by host resistance and tumor susceptibility assays in mice.as part of a program to develop and validate methodology to measure chemically induced immunotoxicity, the effect of des on resistance of adult b6c3f1 female mice to various microorganisms and to challenge with syngeneic tumor cells was evaluated. the mice received sc injections of 50 microliter corn oil alone or of corn oil containing the equivalent of 0.2, 1, and 4 mg des/kg x d for 14 d. three days later they were challenged with listeria monocytogenes, streptococcus sp. influenza virus, herp ...19836620414
[blood of healthy bulls and those with listeriosis with regard to the enzymatic differences in the lymphocytes].a relationship between esterase positive and esterase negative lymphocytes in peripheral blood of a homogenous group of one-year old healthy bulls of ncb breed was found. average values of other hematologic indices in these animals were also determined. then the same indices were examined in bulls experimentally infected with listeria monocytogenes and compared with the data for healthy animals. the following representative average values were found: erythrocytes 7,2 mill/mm3, leukocytes 8,6 tho ...19836634456
rifampin: spectrum of antibacterial activity.rifampin was studied for determination of its spectrum of activity against many bacteria of clinical importance. most of the minimum inhibitory concentrations (mics) were determined by agar dilution but some were determined by broth microdilution. staphylococci were the most susceptible, with mode mics of 0.015 microgram/ml, but most streptococcal strains, except streptococcus faecalis, had mode mics less than or equal to 1 microgram/ml. haemophilus influenzae, neisseria gonorrhoeae, neisseria m ...19836635433
abortion and stillbirth associated with chlamydia psittaci var ovis in dairy goats with high titers to toxoplasma gondii.during two consecutive breeding seasons in a brucellosis-free dairy goat herd, approximately 40% to 70% of the does (mean herd size, 14.5) had stillbirths or aborted. none of the does aborted or had stillbirths twice. in the first breeding season, 9 of 13 does aborted in the last 2 months of gestation. three fetuses and 2 fetal placentas from 2 does were examined. microscopic findings included severe multifocal hepatic necrosis, mild pneumonia, and mild multifocal necrosis in the brain. cultures ...19836654724
peritonitis due to listeria monocytogenes complicating continuous ambulatory peritoneal dialysis. 19836655293
prevention of the enhancing effect of mucin and iron in mouse meningococcal infection.in vivo resistance of mice to neisseria meningitidis was entirely abrogated by a concomitant administration of mucin and iron with n. meningitidis organisms. resistance, however, was restored when the latter challenge was given to animals which had been immunized 7 days previously with a crude extract of meningococcal antigens (ma), bcg, or proteose peptone. these results suggest that depression or activation of the reticuloendothelial system (res) may be important in resistant of mice to mening ...19836673819
tumor-dependent resistance of rat peritoneal macrophages to herpes simplex virus.by their position at sites of initial infection and their wide distribution in major organs of the body, macrophages may be decisive in determining the susceptibility or resistance of the host to virus infection. macrophage restriction of virus replication has been shown to be closely related to virus strains or virus types and to the age of the infected host. we report the effects of the development of a solid tumor in rats on intrinsic in vitro macrophage activity against herpes simplex virus ...19836299945
characteristics of mononuclear phagocytes mediating antilisterial resistance in splenectomized mice.the characteristics of mononuclear phagocytes mediating resistance to infection with listeria monocytogenes during the early phase (up to 48 h) of the response were investigated in mice of the a strain that had undergone splenectomy. although irradiation in the sham-operated host had no effect on its antilisterial response when administered immediately before infection, it markedly reduced the ability of the splenectomized host to resist listerial challenge. this effect of radiation was demonstr ...19836299948
comparative biochemical and cytochemical studies on superoxide and peroxide in mouse macrophages.maximal rates of superoxide (o-2) release, and the cytochemical locales of peroxide staining in resident, elicited, and activated macrophages have been determined. macrophages elicited into the peritoneum with either casein (1.2% w/v) or proteose-peptone (10.0% w/v) release about twice as much o-2 as macrophages activated by infection of the animals with either listeria monocytogenes, or bacille calmette-guerin (bcg) followed by immune boosting with purified protein derivative (ppd) (i.e., about ...19836302106
lack of virus-specific bacterial adherence to bovine embryonic lung cells infected with bovine parainfluenza virus type 3.infection of bovine embryonic lung cells with bovine parainfluenza virus type 3 did not induce in vitro, virus-specific, hemadsorption-related adherence of corynebacterium pyogenes, haemophilus somnus, staphylococcus aureus, streptococcus zooepidemicus, pasteurella haemolytica, listeria monocytogenes, escherichia coli, pasteurella multocida, brucella sp., or salmonella typhimurium.19836302133
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