Publications

modulation by centrifugation of cell susceptibility to chlamydial infection.	enhancement of chlamydial infection of cell monolayers by centrifugation was shown to depend on induced cell surface changes. evidence for this came from analysis of two forms of organism attachment which take place during centrifugation. in 'productive binding', organisms attached to cells and then entered and infected them. in 'unproductive binding', organisms became attached to cells but were not ingested. these organisms could be stripped from the cells by treatment with trypsin and could th ...	1979	458425
specific prophylaxis of enzootic chlamydial ovine abortion.	a vaccine against chlamydial ovine abortion was prepared according to an original method and experimentally applied to more than 500,000 animals in large breeding units. the vaccine induced a considerable seroconversion (as demonstrated by complement fixation tests) and reduced by 3--5 times the damage due to chlamydioses. vaccination of primiparous ewes, followed by 2--3 annual revaccinations, gave good results, conferring resistance on the vaccinated animals.	1979	462791
interaction of chlamydia psittaci reticulate bodies with mouse peritoneal macrophages.	noninfectious reticulate bodies of chlamydia psittaci are readily phagocytized by thioglycolate-elicited mouse peritoneal macrophages in monolayer culture. the internalized reticulate bodies are rapidly destroyed as indicated by a 60 to 70% decrease in trichloroacetic acid-precipitable radioisotopic counts in the macrophage pellet by 10 h and a concomitant increase of the trichloroacetic acid-soluble radiolabeled chlamydial nucleic acid in the cytoplasm. this intracellular destruction of reticul ...	1979	468374
deoxyribonucleic acid synthesis, cell cycle progression, and division of chlamydia-infected hela 229 cells.	the fate of lymphogranuloma venereum strain chlamydia-infected hela 229 cells was examined by determining the rate of deoxyribonucleic acid synthesis and the kinetics of entry into and progression through s phase and by time-lapse cinemicrography. at an input multiplicity of 5 or less, chlamydia-infected cells showed no inhibition of host deoxyribonucleic acid synthesis or cell cycle progression. cinemicrography showed division of inclusion-containing cells, with one or both daughters receiving ...	1979	468381
changes in the ultrastructure of chlamydia psittaci produced by treatment of the host cell with deae-dextran and cycloheximide.		1979	469985
prospective study of maternal and infantile infection with chlamydia trachomatis.	we examined the prevalence of chlamydial infection in a population of pregnant women and observed their infants to determine the risk of development of ocular or respiratory infection. we examined endocervical and serum specimens from 322 pregnant women for chlamydia trachomatis and chlamydial antibody. the cultures were obtained at the first prenatal visit. six (2%) of the women were infected with c trachomatis. chlamydial antibody was present in the genital secretions of 47% and 73% of the ser ...	1979	471604
infections with chlamydia trachomatis.		1979	471621
chlamydial genital infections: a growing problem.		1979	478491
chlamydia: the organism and neonatal infection.		1979	478514
stimulation of peroxidase by chlamydial infection: cytochemistry of guinea pig conjunctival epithelium.	guinea pig inclusion conjunctivitis, a naturally occurring chlamydial disease of guinea pigs, resolves spontaneously after 3 to 4 weeks. the factors responsible for curbing the infection have not yet been specifically defined. since iwata (invest. ophthalmol. 15:297-301, 1976) reported cytochemical activity for peroxidase in the conjunctival epithelium of the normal rat, we undertook these studies to determine whether a similar activity exists in the guinea pig, and if so, whether it functions i ...	1979	478644
cytochalasin b does not inhibit ingestion of chlamydia psittaci by mouse fibroblasts (l cells) and mouse peritoneal macrophages.	cytochalasin b did not inhibit ingestion of chlamydia psittaci by either mouse fibroblasts (l cells) or mouse peritoneal macrophages in concentrations that produced distinctive morphological changes and inhibited phagocytosis of polystyrene latex beads and escherichia coli k-12.	1979	478646
use of hela cell guanine nucleotides by chlamydia psittaci.	exogenous guanine was found to be incorporated into the nucleic acids of chlamydia psittaci when the parasite was grown in hela cells containing hypoxanthine guanine phosphoribosyltransferase (ec 2.4.2.8) activity but not when the parasite was grown in transferase-deficient hela cells. no evidence for a chlamydia-specific transferase activity was found in either transferase-containing or transferase-deficient infected hela cells. it is concluded that c. psittaci is incapable of metabolizing guan ...	1979	478649
[tissue penetration of erythromycin (author's transl)].	although erythromycin has been used in therapy for more than 25 years, until now there has been no paper summarizing the data on tissue penetration. the present review documents in detail dose- and time-related peak serum levels of erythromycin derivatives after oral administration, in addition to the erythromycin tissue levels. the erythromycin tissue levels often manifoldly exceed the corresponding mic values of pathogens sensitive to erythromycin. however, erythromycin does not penetrate the ...	1979	478653
chlamydial infection of mothers and their infants.	in 340 women, cultured prospectively during their pregnancies, the rate of infection with chlamydia trachomatis was 8.8%. the women with positive cultures tended to be younger and more often single and black than their counterparts with negative cultures. there were no statistically significant clinical differences between the two groups. eighteen children born to chlamydia culture-positive women and 16 born to negative women were followed for nine months to examine the potential effects of mate ...	1979	480010
infertility and cervical chlamydia trachomatis infections.	of the 51 women examined for infertility, 19.6 per cent were found chl. trachomatis culture-positive. this differs, although not significantly, from the 9 per cent isolation rate among our general gynecological outpatients. the results suggest that chl. trachomatis should be considered in women with unexplained infertility.	1979	484224
[infantile chlamydia trachomatis pneumonia: radiographic features].		1979	485074
[action of penicillin on the causative agent of paratrachoma in the dynamics of an in vitro infection].	monolayer cultures of l-cells (mouse fibroblasts) were inoculated with the causative agent of paratrachoma (strain lb-i). simultaneously penicillin in doses of 0.01, 0.1, 1, 10, 25, 50, 100, 150 and 200 microgram/ml was added and its effect on the causative agent in the infection dynamics (18, 24, 48 and 72 hours after the inoculation) was studied with the light and electron microscopes. gradual changes in the ultrastructure of the vegetative forms were observed by the 24th hour with the use of ...	1979	485107
the need for a chlamydial culture service.	in a prospective study of unselected, female patients attending a sexually transmitted disease clinic one in eight patients would have been errouneously declared free of infection in the absence of a chlamydial culture service. chlamydia trachomatis is now accepted as a causative organism of non-specific urethritis and post-gonococcal urethritis in men and non-specific genital infection in women. thus, facilities for isolation of c. trachomatis should be an essential aid in the management of wom ...	1979	486248
non-specific genital infection.		1979	486977
non-specific genital infection.		1979	486978
activity of antimicrobials against chlamydia trachomatis in vitro.		1979	489497
chlamydia trachomatis diseases are on the rise.		1979	490867
susceptibility of chlamydia trachomatis to antibiotics in vitro and in vivo.	the susceptibility of chlamydia trachomatis to antibiotics was studied in vitro and in patients with nongonococcal urethritis. the minimal inhibitory concentrations of cloxacillin, erythromycin, pivampicillin, oxytetracycline, and doxycycline, which were the most effective drugs, were 10, 0.5, 0.25, 0.1, and 0.5 microgram/ml, respectively. the clinical observations suggested that of the antibiotics studied, doxycycline, erythromycin, and trimethoprim-sulfamethoxazole were effective for treatment ...	1979	494040
wheat germ agglutinin blockage of chlamydial attachment sites: antagonism by n-acetyl-d-glucosamine.	addition of 2 to 10 micrograms of wheat germ agglutinin (wga), a lectin from triticum vulgaris specific for n-acetyl-d-glucosamine, per ml to suspensions of mouse fibroblasts (l cells) blocked the attachment of 14c-labeled chlamydia psittaci 6bc to the l-cell surface. wga and strain 6bc competed for similar sites on l cells, but once bound, one was not replaced by the other. n-acetyl-d-glucosamine, but not other monosaccharides of related structure, antagonized the blocking action of wga. lectin ...	1979	500195
[chlamydia infection as a cause of acute salpingitis].		1979	505603
infective endocarditis with glomerulonephritis associated with cat chlamydia (c. psittaci) infection.	a patient with glomerulonephritis and endocarditis is described who had evidence of feline chlamydia psittaci infection. treatment with antichlamydial drugs resulted in resolution of the glomerulonephritis and the endocarditis. it is recommended that screening for chlamydia is included in the investigation of patients with suspected or obscure endocarditis.	1979	508458
juxtapapillary choroiditis in association with rising antichlamydial antibody.	we present the case of a 21-year-old girl with a uniocular juxtapapillary choroiditis. during the course of her illness the titre of antichlamydial igg increased from 1/32 to 1/4096 against chlamydia trachomatis tric serotypes j and c, and antichlamydial igm appeared in her blood. toxoplasma dye test was positive at a level of 1/128 but no increase in the titre of antibody was detected during the course of her infection. the relevance of these findings to her ocular lesion is discussed.	1979	508692
vaginal oxytetracycline concentrations.	although tetracycline preparations are widely used in departments of genitourinary medicine, or sexually transmitted diseases clinics, little is known of the concentrations of these preparations in genital secretions. for this reason a microbiological method was used for estimating oxytetracycline concentrations in vaginal secretions. these concentrations varied from 0.6 to 6.5 microgram/ml in 19 women who had had sexual contact with a man with non-specific urethritis and who were taking oxytetr ...	1979	509190
persistent urethral leukocytosis and asymptomatic chlamydial urethritis.	chlamydia trachomatis was isolated from 47% of asymptomatic, sexually active men whose urethral smears contained four or more polymorphonuclear leukocytes (pmn) per high-power field (hpf) one week after their sexual activity was restricted. c. trachomatis was not detected in any of 23 asymptomatic, sexually active men having less than 4 pmn/hpf in two urethral smears obtained one week apart. semiquantitation of urethral pmn in the urethral gram-stained smear is useful in the evaluation of asympt ...	1979	512420
symposium on the spondylarthritides. spondylarthritis and the post-infectious syndromes.		1979	515626
serological cross-reactions between acinetobacter calcoaceticus and chlamydiae.	a cross-reaction between acinetobacter calcoaceticus and chlamydiae is described. a water-soluble, heat stable, non-dialyzable antigen was extracted from acinetobacter species by boiling. this antigen fixed complement in the presence of homologous hyperimmune sera from rabbits or guinea pigs and in the presence of heterologous human or hyperimmunized animal sera containing chlamydial antibodies. hyperimmune antisera to the extracted antigen, or to suspensions of live acinetobacters, also reacted ...	1979	521480
differential neutralization of spontaneous and centrifuge-assisted chlamydial infectivity.	neutralization by specific antibody of a fast-killing variant strain of chlamydia trachomatis, which showed high spontaneous infectivity for cell monolayers, was examined. it appeared that in spontaneous infection antibody-treated chlamydiae were neutralized by inhibition of attachment to cells. centrifugation imposed a different effect: infection was inhibited at some step at or subsequent to attachment.	1979	521795
isolation of a chlamydial agent from rocky mountain bighorn sheep.	a total of 53 clinical specimens from both healthy and diseased rocky mountain bighorn sheep (ovis canadensis) were examined for chlamydia. an agent consistently lethal for chicken embryos was recovered from a nasal swab taken from a normal ewe. this agent, designated bhs-15, possesses antigens which fix complement in the presence of anti-chlamydial serum, is susceptible to chlortetracycline, and is resistant to sodium sulfadiazine and streptomycin. attempts to culture the isolate in quality con ...	1979	522218
[a focus of abortive chlamydiosis of goats in chad].		1979	523726
[possibility of human infection studied in foci of animal chlamydiasis].		1979	524804
pneumonia associated with chlamydia trachomatis infection in an infant.	chlamydia trachomatis was isolated from the epipharynx of a 10-week-old baby girl taken ill with pneumonia but without signs of conjunctivitis. the infant developed specific antibodies to the organism. the course of the pneumonia was protracted, with cough and tachypnea. the baby, who was afebrile, improved on antibiotic therapy but pulmonary infiltrates persisted for several months. to our knowledge, this is the first case of pneumonia in an infant associated with c. trachomatis infection repor ...	1979	525346
chlamydia trachomatis genital infections.	the prevalence and clinical features of chlamydia trachomatis infection were studied in men with nongonococcal urethritis (ngu), in their female sexual partners, and in other women. of 92 patients with ngu, 36 (39%) were chlamydia-positive; although all had symptoms of urethritis, fewer than half had evident discharge. clinical features of chlamydia-positive and chlamydia-negative ngu were indistinguishable. most female contacts of chlamydia-positive patients with ngu were infected with c. trach ...	1979	526844
antichlamydial antibodies in pelvic inflammatory disease.	the role of chlamydia trachomatis in pelvic inflammatory disease (pid) diagnosed without laparoscopy was assessed by measuring antichlamydial antibodies in the patient's serum and by comparing the results with those in patients with uncomplicated non-specific genital infection (nsgi) and gonorrhoea and in non-infected controls. a modified microimmunofluorescence test was used. patients with severe pid had significantly more positive antichlamydial igg and igm results than did control subjects, p ...	1979	526845
chlamydia trachomatis infection of the fallopian tubes. histological findings in two patients.	in two patients with acute salpingitis, c. trachomatis was isolated from the cervix. in one of the patients, the organism was also recovered from the fallopian tubes, and in the other, chlamydial inclusions were found in giemsa-stained tubal epithelial cells. a significant change in micro-immunofluorescence antibodies to c. trachomatis occurred in both patients during the course of the disease. the fallopian tubes of both patients were removed and studied by conventional histological techniques ...	1979	526846
experimental pneumonia in red deer (cervus elaphus l) produced by an ovine chlamydia.	an isolate of chlamydia psittaci from ovine pneumonia produced extensive pneumonia in red deer after endobronchial inoculation. associated clinical signs lasting for several days included pyrexia, inappetance, increased pulse and respiration rate, and physical distress after handling, but no coughing or upper respiratory symptoms. histologically, an acute exudative reaction was present after two days, and an early proliferative response after seven days. both the clinical and pathological respon ...	1979	532073
[a method for the preparation of a chlamydiae group-specific antigen on hela-229 cells infected with a strain of "chlamydia trachomatis" for use in the complement fixation test (author's transl)].	a simple method for the preparation of a potent group-specific antigen on hela-229 cells infected with mrc-1 (lb) (tric/gb/mrc-1 gf) strain of chlamydia trachomatis is outlined. hela-229 cells are infected (mrc-1 strain, 102 inclusion-forming units per cell) with centrifugation at 4,000 g for 1 h in flat-bottomed vials. the cells are removed by brief trypsinization with 0.25% trypsin and put into 75 cm2 culture flasks (12 x 106 cells by flask) in bhk-21 medium supplemented with foetal bovine ser ...	1979	533072
chlorhexidine as an effective agent against chlamydia trachomatis in vitro and in vivo.	in a small field trial, chlorhexidine (50 micrograms/ml) was as effective against clinical trachoma as topical tetracyclines or oral co-trimoxazole; in vitro, 2.5 micrograms/ml was chlamydicidal.	1979	533265
the isolation of chlamydia agents from conjunctival scrapings of sheep with keratoconjunctivitis.		1979	533497
clinical evaluation of a commercial vaccine against chlamydial abortion of ewes.	the immunity of ewes vaccinated prior to breeding with an adjuvant vaccine prepared from yolk sac propagated chlamydiae, was challenged at 70 days of pregnancy by intravenous (iv) or intradermal (id) inoculation of a suspension of virulent yolk sac propagated chlamydiae. the response to challenge inoculation was followed by recording rectal temperature, cf antibody titer, lambing performance and by chlamydial isolation from vaginal swabs. that vaccine did not protect against iv challenge: 7 of 1 ...	1979	539776
detection of antibodies against some respiratory pathogens in the sera of domestic animals in egypt. a preliminary communication.		1979	540179
infection of untreated primary human amnion monolayers with chlamydia trachomatis.	for development of a laboratory model for chlamydial infection of the human genital tract, untreated primary human epithelial cell monolayers, prepared from each of four placentas, were infected with a stock strain of chlamydia trachomatis isolated from the nasopharynx of an infant with pneumonia. infectivity titrations were performed with use of standard procedures of chlamydial inoculation, and inclusions grown in amnion cell monolayers and in mccoy cells were measured versus infectious units ...	1979	541524
genital infections with chlamydia trachomatis.		1979	542157
[erythema nodosum associated with chlamydia infections].		1979	544249
experimental transmission of chlamydia psittaci to turkeys from wild birds.	wild birds were inoculated with chlamydia psittaci to determine species that could be potential hosts and vectors in transmitting the agent to domestic turkeys. infection occurred in turkeys exposed to starlings (sturnus vulgaris), common grackles (quiscalus quiscula), brown-headed cowbirds (molothrus ater), and inca doves (cardafella inca). mourning doves (zenaidura macroura) shed the agent sparingly, but turkeys exposed to them did not become infected, these findings and knowledge of the habit ...	1979	546413
the aetiology of a keratoconjunctivitis occurring in goats in the sudan.	an infectious keratoconjunctivitis occurring in goats in the sudan is described. experimental transmission using infective ocular discharges resulted in a conjunctivitis in young kids and a severe keratoconjunctivitis in an adult goat. a pleomorphic organism which resembled rickettsia spp was found in conjunctival smears from naturally and experimentally infected animals. neither mycoplasma nor chlamydia spp were isolated in microbiological cultures.	1979	552726
field studies on enzootic abortion of ewes in south east scotland.	statistical data were collected from 20 sheep flocks in which enzootic abortion of ewes (eae) was diagnosed by examination of fetal material and maternal blood samples. the abortion rate in the 10,645 ewes in these flocks was 7.6 per cent. thirteen of the flocks were fully vaccinated against eae but the abortion rate in these was still in the order of 6.5 per cent. eae was the major cause of the problem as ascertained from the laboratory examination of samples from a wide range of cases of abort ...	1979	552732
[the replication cycle of chlamydia trachomatis and chlamydia psittaci: ultrastructural analysis].	an ultrastructural comparative analysis is reported on the replication cycle of six strains of chlamydia trachomatis, recently isolated, and chlamydia psittaci strain 6bc, grown in cell cultures. important morphological distinctions of the bacterial walls are documented. in chlamydia trachomatis the cell wall seems more rigid. this causes, during the morphogenesis of the elementary body, its separation from the cell membrane with formation of an electron transparent space, which is not demonstra ...	1979	553521
[antibodies against chlamydia trachomatis in patients with non-gonococcal urethritis and in the healthy italian population].	the authors report the results of a study on the prevalence of serum antibodies against chlamydia trachomatis among patients with non-gonococcal urethritis caused by chlamydia trachomatis and diagnosed on the basis of the isolation of the microorganism in cell cultures, among patients with non-gonococcal urethritis of unknown etiology and in groups of healthy population, in italy. the search for antibodies was performed both with complement-fixation tests in micro-titer system, using an antigen ...	1979	553522
treatment of nongonococcal urethritis with rifampicin as a means of defining the role of ureaplasma urealyticum.		1979	371746
fifteen-month follow-up study of women infected with chlamydia trachomatis.		1979	758599
ophthalmia neonatorum due to chlamydia trachomatis: a family problem?	the most frequently seen type of infectious ophthalmia neonatorum, inclusion conjunctivitis, is caused by the organism chlamydia trachomatis. this agent is known to be transmitted sexually. until recently, the infections produced by c trachomatis were though to be relatively benign. recent evidence, however, suggests that the organism may produce urethritis and epididymitis in the male; cervicitis, cervical erosions, salpingitis, and puerperal infections in the female; and prematurity and pneumo ...	1979	759548
chlamydiae, cervicitis, and abnormal papanicolaou smears.	cervical abnormalities accompanied by papanicolaou class ii or class iii cytologic results are commonly encountered in gynecologic office practice. chlamydiae are a common cause of genital tract infection, with or without manifest symptoms or signs. an immunofluorescence method was used to determine the presence of antichlamydial antibodies in cervical secretions. eleven of 15 patients in whom such antibodies were found (73.3%) had papanicolaou class ii or class iii smears, in contrast to only 3 ...	1979	760016
[current venereological problems].		1979	760074
comparative investigations on the value of seroreactions for the diagnosis of chlamydial and rickettsial infections.		1979	581812
[a preliminary study of the occurrence of chlamydia trachomatis in the urogenital tract, the rectum and the oropharynx of persons visiting a venereological clinic].		1979	581895
[mixed infections transmitted sexually].		1979	582864
[clinical significance of chlamydia infections in obstetrics and gynecology (with special reference to the female urethral syndrom) (author's transl)].		1979	583301
chlamydial genital tract infections.		1979	581565
nongonococcal urethritis.		1979	286194
who workshop on sexually transmitted diseases (std) suva, fiji, 2--12 april 1979.		1979	290908
genital tract-to-eye infection: tissue culture of chlamydia trachomatis.	a method of cell culture using hela 229 cells is described for the isolation of chlamydia trachomatis. from 40 patients with non-specific urethritis (nsu) attending a venereal disease clinic, the isolation rate was 60 percent and 78 percent from neonates with sticky eyes from which no other organism could be isolated.	1979	292852
[non-gonococcal urethritis in men: epidemiology and etiology].		1979	314123
[non-gonorrheal urethritis in men. clinical aspects, diagnosis and treatment].		1979	316550
sexually acquired reactive arthritis.		1979	318102
[the psittakosis, lymphogranuloma, trachoma group (author's transl)].		1979	572049
prevalence of ornithosis and other chlamydia-like infections in the ukrainian ssr.	the prevalence of ornithosis and other chlamydia infections among various groups of the population, some species of birds and mammals was studied in several regions of the ukrainian ssr. among the town population having no occupational contact with domestic fowl and farm animals, complement-fixing antibodies to group ornithosis antigen were found in 6.5% of the examined, among the inhabitants of rural localities in 8.4% and among the workers of poultry farms in 19.9%. during the examination of t ...	1979	575382
target tissues associated with genital infection of female guinea pigs by the chlamydial agent of guinea pig inclusion conjunctivitis.	female guinea pigs were experimentally infected in the genital tract with the strain of chlamydia psittaci that causes guinea pig inclusion conjunctivitis. chlamydiae were found frequently in superficial squamous epithelial cells of the exocervix, along with heavy involvement at the squamocolumnar junction. in this zone chlamydiae were observed in columnar cells, but inflammation and chlamydial inclusions were not observed in true endocervical epithelium. these observations were supported by res ...	1979	374637
protective effects of supplemental vitamin e against infection.	vitamin e supplementation (dl-alpha-tocopheryl acetate except where noted) in excess of requirement significantly increased humoral immune response or disease resistance. mice immunized with sheep red blood cells or tetanus toxoid and fed the supplemental vitamin demonstrated increased plaque-forming cells (pfc) and hemagglutinin (ha) titers. a vitamin e deficiency resulted in decreased pfc and little igg which was partially corrected by n,n-diphenyl-p-phenylenediamine but not as effectively as ...	1979	376353
chlamydial serology in infertile women by immunofluorescence.	the chlamydial serum immunoglobulin g antibodies of 128 infertile women were determined by a single-antigen (l2) immunofluorescence test. the antibody titers were compared with those of female contacts of men with nonspecific urethritis and with those of "normal" pregnant women. among infertile women, 43% lacked chlamydial antibodies (titer less than or equal to 8). the corresponding proportion for contacts of men with nonspecific urethritis was 14% and that for pregnant women 71%. a very high t ...	1979	376359
etiology, manifestations and therapy of acute epididymitis: prospective study of 50 cases.	there were 50 patients with acute epididymitis who were evaluated prospectively by history, examination and microbiologic studies, including cultures for aerobes, anaerobes, neisseria gonorrhoeae, chlamydia trachomatis and ureaplasma urealyticum. escherichia coli was the predominant pathogen isolated from the urine of men more than 35 years old, while chlamydia trachomatis and neisseria gonorrhoeae were the predominant pathogens isolated from the urethra of men less than 35 years old. the etiolo ...	1979	379366
chlamydial infections.		1979	379774
host modification of chlamydiae: differential infectivity for cell monolayers of chlamydiae grown in eggs and monolayers.	cell monolayer-grown chlamydiae (cgo) differed from egg-grown organisms (ego) in their increased spontaneous infectivity relative to centrifuge-assisted infectivity for monolayers. for each population spontaneous: centrifuge-assisted infectivity ratios were constant over a wide dose range. spontaneous infection increased linearly with time and could not be exhausted from either population by prolonged adsorption; there was no change in infectivity ratios in residual supernatants. further, one pa ...	1979	383898
host modification of chlamydiae: presence of an egg antigen on the surface of chlamydiae grown in the chick embryo.	egg-grown chlamydiae (ego) have a yolk sac antigen assoicated with their surface which is absent from cell monolayer-grown organisms (cgo). ego infectivity was specifically neutralized by rabbit antiserum to normal yolk sac; cgo infectivity, before or after incubation with normal yolk sac material, was not neutralized. treatment of ego with clostridium welchii culture filtrate, containing phospholipase c, abolished spontaneous infectivity for monolayers and neutralization by anti-yolk sac antise ...	1979	383899
prevalence of certain antibodies to selected disease-causing agents in wild turkeys in texas.	in texas in 1976 and 1977, rio grande turkeys (meleagris gallopavo intermedia) from seven counties and eastern turkeys (m. g. silvestris) from one county were tested for antibodies to selected poultry pathogens. standardized serological tests disclosed reactors to salmonella pullorum (2.4%), s. typhimurium (2.3%), and mycoplasma gallisepticum (4.8%). there were no reactors to newcastle disease virus or chlamydia psittaci. prevalence of m. gallisepticum antibody in wild turkeys was significantly ...	1979	384989
reticulate bodies as single antigen in chlamydia trachomatis serology with microimmunofluorescence.	formalin-fixed, purified reticulate bodies (rb) of chlamydia trachomatis immunotype c/tw-3/ot were used as a serological test antigen in the microimmunofluorescence test. the sensitivity and specificity of the rb antigen were compared to elementary bodies (eb) used as antigens in the detection of c. trachomatis antibodies in human sera by microimmunofluorescence. rb reacted with all known c. trachomatis immunotypes with the same sensitivity as the homotypic eb. in routine serology with sera and ...	1979	385620
chlamydia trachomatis-induced urethritis in female partners of men with nongonococcal urethritis.	the rate of isolation of chlamydia trachomatis from cervical and urethral specimens from 99 culture-positive female partners of men with nongonococcal urethritis who were attending a gynecological outpatient clinic was correlated with the clinical status of the women. the agent was recovered from both sites in 46 women, from the cervix only in 28, and from the urethra only in 25 women. urethral symptoms were reported by 38 (54%) of those with positive urethral cultures, as compared with six (21% ...	1979	386533
the importance of coexisting syphilitic, chlamydial, mycoplasmal, and trichomonal infections in the treatment of gonorrhea.		1979	386536
chlamydial infections. microbiological, clinical and diagnostic aspects.	the agent of trachoma, originally regarded as a virus, was described by halberstadter and von prowacek in 1907. since then, studies on chlamydiae have shown that they are procaryocytic organisms that infect eucaryocytic cells as obligate intracellular parasites. infections caused by these pathogenic agents occur in a wide range of avian and mammalian species. chlamydiae are also responsible for several diseases in man, and there is a rapidly growing awareness of their public health significance. ...	1979	388102
comparison of various mccoy cell treatment procedures used for detection of chlamydia trachomatis.	mccoy cells treated in six different ways, in addition to untreated cells, were compared to determine which gave rise to the largest number of chlamydia trachomatis inclusions when tested with a laboratory-passaged strain. the same batch of cells was treated by irradiation, preinoculation exposure to cytochalasin b or 5-iodo-2'-deoxyuridine, and postinoculation exposure to cycloheximide, hydrocortisone, or emetine. significantly more inclusions were always found in cells which had been treated w ...	1979	389948
formalinized chlamydia trachomatis organisms as antigen in the micro-immunofluorescence test.	chlamydia trachomatis organisms grown in hela 229 cell cultures were purified and formalinized for use in the micro-immunofluorescence test. as test antigens, they were stable when stored unfrozen at 4 degrees c for a long period of time without loss of type specificity and sensitivity.	1979	389953
diagnostic specificity of immunoglobulin m (igm) response in differentiation legionnaires' disease from psittacosis.	specific igm and igg antibody responses to legionella pneumophila (ldb) and chlamydia psittaci (psi) in serum specimens from 22 cases of legionnaires' disease (ld) were examined by micro-immunofluorescence (if) tests to explore the diagnostic significance of the igm antibody response. serial samples from 5 patients with ld showed greater than or equal to 4-fold changes in igg antibody against ldb and psi. all 5 patients possessed igm antibodies against ldb but not against psi. in single convales ...	1979	394307
[pathology and pathogenesis of neonatal diarrhea in the calf. i. presentation of the problem and a discussion of its etiology and pathogenesis based on the latest literature].		1979	395641
chlamydia trachomatis--recent knowledge of genital tract-to-eye infections.		1979	396914
failure of serology in diagnosing chlamydial infections of the female genital tract.	chlamydia trachomatis was recoved from 20% (36/180) of women attending a venereal disease clinic. all infected women had chlamydial antibodies in their serum and cervical secretions. however, the background rates of chlamydial antibody in chlamydia-negative women were very high. measurement of antibodies in serum (complement fixation or immunoglobulin g [igg] and igm by microimmunofluorescence) or cervical secretion (igg, igm, iga or secretory iga classes) did not result in predictive values of ...	1979	397220
immunological evidence of chlamydial infection in reiter's syndrome.		1979	400765
antibiotic treatment in reiter's syndrome.		1979	263467
[gynecologic infections--diagnosis and therapy in general practice and by the specialist].		1979	215967
sexually transmissible vaginal infections in pregnancy. 2. less common infections.		1979	218182
growth and effect of chlamydiae in human and bovine oviduct organ cultures.		1979	223717
genital infections of perinatal importance.		1979	223788
genital chlamydia trachomatis infections in patients with cervical atypia.	of 177 gynecologic outpatients with cervical dysplasia studied, 29 (16%) were found to excrete chlamydia trachomatis from their urogenital tract. sera collected from 93 of these patients were significantly more often positive for and showed higher levels of antichlamydial micro-complement fixation (cf) and immunofluorescence (if) antibodies than sera obtained from the controls. however, when the sera were tested for anti-herpesvirus type ii (hsv-ii) and cytomegalovirus (cmv) antibodies, no diffe ...	1979	224353
prevalence of nine different micro-organisms in the female genital tract. a comparison between women from a venereal disease clinic and from a health control department.	in a study of the prevalence of nine different micro-organisms in the female genital tract in a swedish population, significantly higher isolation rates occurred among women attending a venereal disease clinic than among those attending a gynaecological health control department. the prevalence of candida albicans, however, was similar in different groups, individual susceptibility being the most important factor. chlamydia trachomatis, trichomonas vaginalis, and mycoplasma hominis occurred conc ...	1979	230884
[pathomorphology in chlamydial-parainfluenzal infection in calves].		1979	232328
the relationship between genetics and environment in the pathogenesis of rheumatic diseases.	major developments have taken place to further our understanding of the relationship between genetics and the environment in the pathogenesis of rheumatic disorders. the association between hla markers and human disease is becoming clearer. for instance, hla-drw4 frequently occurs in patients with rheumatoid disease, and penicillamine and gold toxicity are seen most often in patients with hla-drw2 or drw3. antisera to b alloantigens help define the genetic differences between systemic lupus eryt ...	1979	18748470
chlamydiae in reiter's syndrome.		1980	6101372