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assessment of adverse events associated with antiretroviral regimens for postexposure prophylaxis for occupational and nonoccupational exposures to prevent transmission of human immunodeficiency virus.to assess adverse events associated with antiretroviral regimens for human immunodeficiency virus (hiv) postexposure prophylaxis (pep), with a particular focus on the treatment combination of zidovudine, lamivudine, and tenofovir (zdv-3tc-tdf).200717520543
bioinformatics and human identification in mass fatality incidents: the world trade center disaster.victim identification initiatives undertaken in the wake of mass fatality incidents (mfis) where high-body fragmentation has been sustained are often dependent on dna typing technologies to complete their mandate. the success of these endeavors is linked to the choice of dna typing methods and the bioinformatic tools required to make the necessary associations. several bioinformatic tools were developed to assist with the identification of the victims of the world trade center attacks, one of th ...200717524061
does integrating viral hepatitis services into a public std clinic attract injection drug users for care?injection drug users (idus) are at high risk for multiple health problems, including human immunodeficiency virus (hiv), viral hepatitis, and sexually transmitted diseases (stds), and are likely to have poor access to health care. to more effectively serve high-risk clients, experts recommend that programs accessed by such client populations offer integrated services. in 2000, the new york city department of health and mental hygiene integrated viral hepatitis services (vaccine and screening) in ...200717542450
promoting hcv treatment completion for prison inmates: new york state's hepatitis c continuity program.this article describes the development of a statewide program providing continuity of hepatitis c virus (hcv) treatment to prisoners upon release to the community. we discussed length of stay as a barrier to treatment with key collaborators; developed protocols, a referral process, and forms; mobilized staff; recruited heath-care facilities to accept referrals; and provided short-term access to hcv medications for inmates upon release. the hepatitis c continuity program, including 70 prisons and ...200717542460
advancing biocultural models by working with communities: a partnership approach.culture and human behavior are recognized today as major forces acting on human biological variation around the world. studies of the relationships between biology and processes, such as modernization, urbanization, and social stratification, are prominent in our journals and meetings. an ongoing study of the interrelationships between toxicant exposure (organochlorines, lead, and mercury), health, and culture among youth of the mohawk nation at akwesasne is located within this context and is us ...200717546616
plasma epstein-barr virus immunoglobulin a and dna for nasopharyngeal carcinoma screening in the united states.to examine the epstein-barr virus (ebv) iga and dna assays as a screening tool for nasopharyngeal carcinoma (npc) in a nonendemic us population.200717547994
association of polymorphisms in myeloperoxidase and catalase genes with precancerous changes in the gastric mucosa of patients at inner-city hospitals in new york.gastric carcinogenesis is a multistep process progressing from chronic gastritis, through glandular atrophy (ga), intestinal metaplasia (im) and dysplasia. we have previously demonstrated that minority patients at new york city hospitals are infected with a relatively virulent strain of h. pylori (hp) and that hp infection is associated with an increased incidence of precancerous changes in the gastric mucosa. nevertheless, precancerous changes are not observed in every hp-infected individual, s ...200717549373
computer-based multivariate economic analysis of neonatal-intensive-care-unit-based influenza vaccine administration to parents in a low-socio-economic, urban setting.trivalent inactivated influenza vaccine has been shown to reduce the number of influenza-related outpatient visits and hospitalizations of children up to 24 months of age. the american academy of pediatrics, centers for disease control, and advisory committee on immunization practices recommend that the influenza vaccine be administered to the first-person contacts of infants less than 6 months of age. however, the economic implications of increasing immunization rates by using the neonatal inte ...200717549758
west nile virus activity--united states, 2006.west nile virus (wnv) is the leading cause of arboviral encephalitis in the united states. originally discovered in africa in 1937, wnv was first detected in the western hemisphere in 1999 in new york city. since then, wnv has caused seasonal epidemics of febrile illness and severe neurologic disease in the united states. this report summarizes provisional wnv surveillance data for 2006 reported to cdc as of april 3, 2007. during 2006, wnv transmission to humans or animals expanded into 52 count ...200717557072
rapid vaccine distribution in nontraditional settings: lessons learned from project viva.with growing fear of a worldwide influenza pandemic, programs that can rapidly vaccinate a broad range of persons are urgently needed. vaccination rates are low among disadvantaged and hard-to-reach populations living within urban communities, and delivering vaccines to these groups may prove challenging. project viva1 (venue-intensive vaccination for adults), staffed by teams of nurses and outreach workers, aimed to deliver vaccines rapidly within disadvantaged neighborhoods in new york city. p ...200717563280
lyme disease--united states, 2003-2005.lyme disease is caused by the spirochete borrelia burgdorferi and is transmitted to humans by the bite of infected blacklegged ticks (ixodes spp.). early manifestations of infection include fever, headache, fatigue, and a characteristic skin rash called erythema migrans. left untreated, late manifestations involving the joints, heart, and nervous system can occur. a healthy people 2010 objective (14-8) is to reduce the annual incidence of lyme disease to 9.7 new cases per 100,000 population in 1 ...200717568368
rapid hiv testing in emergency departments--three u.s. sites, january 2005-march 2006.approximately one fourth of the estimated 1 million persons living with human immunodeficiency virus (hiv) in the united states are unaware that they are infected with hiv and at risk for transmitting the virus to others. in april 2003, cdc announced a new initiative, advancing hiv prevention: new strategies for a changing epidemic, aimed at reducing barriers to early diagnosis of hiv infection and increasing access of persons infected with hiv to medical care and prevention services. a priority ...200717585288
acute human immunodeficiency virus infection in a breast-fed infant in new york city.acute human immunodeficiency virus (hiv) infection in a breast-fed infant is a rare diagnosis in developed countries. we present a six-month old girl with postnatally acquired hiv infection complicated by pneumocystis jéroveci pneumonia, cytomegalovirus pneumonitis and encephalopathy. her mother had tested negative for hiv during pregnancy. children infected by mothers during an acute seroconversion may have more rapid disease progression.200717596814
symptomatic early neurosyphilis among hiv-positive men who have sex with men--four cities, united states, january 2002-june 2004.symptomatic early neurosyphilis is a rare manifestation of syphilis that usually occurs within the first 12 months of infection. most neurologic symptoms of early neurosyphilis result from acute or subacute meningitis, abnormalities in cranial nerve function, and inflammatory vasculitis leading to a cerebrovascular accident. symptomatic early neurosyphilis essentially disappeared in the united states after the introduction of penicillin treatment for syphilis in the late 1940s but reappeared in ...200717597693
incidence and persistence of staphylococcus aureus nasal colonization in a community sample of hiv-infected and -uninfected drug users.a longitudinal study of 282 community-based drug users was conducted from february 1999 through september 2000. both the incidence (15.0 cases per 100 person-years at risk; 95% confidence interval, 10.2-20.7 cases per 100 person-years at risk) and persistence of staphylococcus aureus carriage were increased among human immunodeficiency virus (hiv)-seropositive individuals.200717599312
the $5 man: the underground economic response to a large cigarette tax increase in new york city.we examined the mechanisms by which living in a disadvantaged minority community influences smoking and illegal cigarette sale and purchasing behaviors after a large cigarette tax increase.200717600270
tracking human travel using stable oxygen and hydrogen isotope analyses of hair and urine.the stable oxygen and hydrogen isotope compositions of organic samples are increasingly being used to investigate patterns of animal migration. relatively few studies have applied these techniques to modern humans, despite a variety of potential forensic applications. we analyzed drinking water and food at two geographic locations, east greenbush, new york (usa) and fairbanks, alaska (usa), with different delta(18)o and deltad values for precipitation and tap water. foods varied widely in measur ...200717610246
incident sexually transmitted infections among persons living with diagnosed hiv/aids in new york city, 2001-2002: a population-based assessment.objective/goal: to describe the incidence of 3 bacterial sexually transmitted infections (stis) among persons living with human immunodeficiency virus (hiv) infection and acquired immunodeficiency syndrome (aids) (plwha) in new york city (nyc) and to identify predictors for sti acquisition.200717621243
multistate outbreak of norovirus gastroenteritis among attendees at a family reunion--grant county, west virginia, october 2006.on october 17, 2006, the west virginia department of health and human resources (wvdhhr) was notified of an outbreak of acute gastroenteritis, characterized by vomiting and diarrhea, among attendees at a family reunion. the outbreak initially was reported by a group of attendees to their local health department in garrett county, maryland. the same day, the information was relayed to the grant county health department in west virginia and subsequently to wvdhhr. the reunion was held on october 1 ...200717625494
the role of lizards in the ecology of lyme disease in two endemic zones of the northeastern united states.we examined the role of lizards in the ecology of lyme disease in new york and maryland. we collected data on vector tick infestations, measured lizard "realized" reservoir competence for the lyme disease spirochete borrelia burgdorferi, and estimated lizard population density. these data were incorporated into a model that predicts a host's ability to influence the prevalence of b. burgdorferi in the tick population, a primary risk factor in the epidemiology of lyme disease. published data on o ...200717626342
raymond v. damadian, m.d.: magnetic resonance imaging and the controversy of the 2003 nobel prize in physiology or medicine.on october 6, 2003 the nobel committee announced that paul c. lauterbur, phd and sir peter mansfield, phd were awarded the nobel prize in physiology or medicine for their work on the development of magnetic resonance imaging. dr. raymond damadian was excluded and a controversy ensued.200717631325
written consent for human immunodeficiency virus testing. 200717639644
human granulocytic anaplasmosis during pregnancy: case series and literature review.we describe the clinical and laboratory manifestations and pregnancy outcomes of 6 women who received a diagnosis of human granulocytic ehrlichiosis during pregnancy. human granulocytic ehrlichiosis did not seem to present in a fulminant fashion, and all treated patients had excellent responses to rifampin or doxycycline therapy. perinatal transmission was documented in 1 neonate, who responded well to treatment. there do not appear to be any long-term adverse sequelae in children born from thes ...200717682993
monitoring the impact of influenza by age: emergency department fever and respiratory complaint surveillance in new york city.the importance of understanding age when estimating the impact of influenza on hospitalizations and deaths has been well described, yet existing surveillance systems have not made adequate use of age-specific data. monitoring influenza-related morbidity using electronic health data may provide timely and detailed insight into the age-specific course, impact and epidemiology of seasonal drift and reassortment epidemic viruses. the purpose of this study was to evaluate the use of emergency departm ...200717683196
hair analysis in sled dogs (canis lupus familiaris) illustrates a linkage of mercury exposure along the yukon river with human subsistence food systems.the dog has been an important biomedical research model and hair samples from sled dogs could be used as a biomarker of exposure to metals. hair samples were used as a non-invasive indicator of mercury exposure in sled dogs fed commercial food and traditional village diets. sled dog populations living in rural new york and alaska were sampled in 2005 and 2006. total mercury (thg) content was determined on the entire hair sample in sled dogs from reference sites in north creek, new york and salch ...200717707466
prevalence of hepatitis b and c virus infections in children infected with hiv.we evaluated the prevalence and transmission mode of hepatitis b and c in an inner-city, pediatric cohort of human immunodeficiency virus (hiv)-infected persons, as well as the demographic characteristics of the cohort. hepatitis b or c was found in 13 (5.8%) of 228 children. this analysis suggests that chronic hepatitis is prevalent and should be routinely screened for in the pediatric hiv-infected population.200717712766
revitalizing the humanistic imperative in nursing education.this article describes a teaching strategy that focuses students' attention on the humanistic imperative in nursing practice. the humanistic teaching method provides a framework for adapting nursing courses to accommodate person-to-person, human-centered nursing care alongside scientific and technological competencies. through this approach, students integrate concepts such as humanism, existentialism, and phenomenology into patient interactions. in addition to producing a favorable effect on pa ...200717715806
violations of human rights: health practitioners as witnesses.for humanitarian health-care practitioners bearing witness to violations of human dignity has become synonymous with denunciations, human rights advocacy, or lobbying for political change. a strict reliance on legal interpretations of humanitarianism and human rights is inadequate for fully understanding the problems inherent in political change. with examples from the hiv/aids epidemic in the usa, the rwandan genocide, and physician-led political activism in nepal, we describe three cases in wh ...200717720021
richard selzer: premiere american surgeon-writer.richard selzer (b.1928) is one of the most prominent american surgeon-authors alive today. only sherwin nuland (b.1930), from yale university medical school as selzer was, carries the same outstanding virtues of good surgery and excellent writing. recently, atul gawande (b. 1965) has taken a road similar to these two distinguished predecessors. selzer has produced 14 books of superb scholarship and immense value for the active and committed surgeon. he describes, with unusual grace and wit, diff ...200718097871
genetic relationships of jamestown canyon virus strains infecting mosquitoes collected in connecticut.jamestown canyon virus (jcv) (family bunyaviridae, genus orthobunyavirus) is maintained in a mosquito-deer cycle and has been implicated in the etiology of meningitis and encephalitis with human cases reported from ontario, canada, michigan, connecticut, and new york. despite the recognition of symptomatic cases in the northeastern united states, little is known about the genetic relationships of jcv variants circulating in this region. accordingly, we compared the phylogenetic relationships of ...200718165540
does the effect of pm10 on mortality depend on pm nickel and vanadium content? a reanalysis of the nmmaps data.lack of knowledge regarding particulate matter (pm) characteristics associated with toxicity is a crucial research gap. short-term effects of pm can vary by location, possibly reflecting regional differences in mixtures. a report by lippmann et al. [lippmann et al., environ health perspect 114:1662-1669 (2006)] analyzed mortality effect estimates from the national morbidity, mortality, and air pollution study (nmmaps) for 1987-1994. they found that average concentrations of nickel or vanadium in ...200718087586
trivalent inactivated influenza vaccine compliance rate in neonatal intensive care unit parents.the american academy of pediatrics (aap) recommends injected, inactivated influenza vaccine for all close contacts of high-risk infants. this population includes parents of infants younger than 59 months of age, with an emphasis on children 0-6 months who are not direct candidates for immunization. this 0-6 month age group is a major component of the neonatal intensive care unit (nicu) population. no data exist on the compliance rate with influenza vaccine in this specific parent population. the ...200718097211
[the establishment of psychiatric genetics in germany, great britain and the usa, ca. 1910-1960. to the inseparable history of eugenics and human genetics].the article reconstructs the emergence of institutionalized research programs in the field of psychiatric genetics. it focuses on the first institutions in this field in germany, the united kingdom, and the united states: the genealogisch-demographische abteilung (gda) at the deutsche forschungsanstalt für psychiatrie in munich founded in 1917/18; the program (later: department) of medical genetics at the new york state psychiatric institute, associated with columbia university, and founded in 1 ...200718447192
the informatics for diabetes and education telemedicine (ideatel) project.telemedicine is a promising but largely unproven technology for providing case management services to patients with chronic conditions who experience barriers to access to care or a high burden of illness. we conducted a randomized controlled trial comparing telemedicine case management to usual care, with blinding of those obtaining outcome data, in 1,665 medicare recipients with diabetes, aged 55 years or greater, and living in federally designated medically underserved areas of new york state ...200718528511
one chip at a time: using technology to enhance youth development.youth development programs have the potential to positively impact psychosocial growth and maturation in young adults. several youth development programs are capitalizing on youths' natural gravitation toward technology as well. research has shown that youth view technology and technologic literacy as positive and empowering, and that youth who master technology have increased self-esteem and better socioeconomic prospects than their counterparts. technology-centered youth development programs o ...200718605656
dietary flavonoid intake and breast cancer risk among women on long island.flavonoids are found in a variety of foods and have anticarcinogenic properties in experimental models. few epidemiologic studies have examined whether flavonoid intake is associated with breast cancer in humans. in this study, the authors investigated whether dietary flavonoid intake was associated with reduced risk of breast cancer in a population-based sample of us women. they conducted a case-control study among women who resided in nassau and suffolk counties on long island, new york. cases ...200717158855
efficacy of an ospa vaccine preparation for prevention of lyme disease in new york state.a multicenter, double-blinded, placebo-controlled study was done comparing a 30-microgram dose of a single protein recombinant ospa vaccine preparation with a saline placebo for efficacy in prevention of lyme disease in humans. the ospa vaccine (30-microgram dose) or saline placebo was given intramuscularly at day 0, 1 month later, and 12 months later. cases of possible lyme disease were evaluated clinically and using culture, polymerase chain reaction and immunoblot assays. safety data are bein ...20079717677
twenty-first century brain banking: practical prerequisites and lessons from the past: the experience of new york brain bank, taub institute, columbia university.generally accepted methods for processing postmortem brains are lacking, despite the efforts of pioneers in the field, and the growing awareness of the importance of brain banking for investigating the pathogenesis of illnesses unique to humans. standardizing methods requires compromises, institutional or departmental mindset promoting collaboration, and the willingness to share ideas, information, and samples. a sound balance between competition and institutional interests is needed to best ful ...200818581261
teaching residents to work with torture survivors: experiences from the bronx human rights clinic.despite the 1984 united nations's convention against torture calling to train doctors to work with torture survivors, many physicians are unaware of their obligation and few are taught the requisite clinical skills.200818612740
same-sex attraction disclosure to health care providers among new york city men who have sex with men: implications for hiv testing approaches.while the centers for disease control and prevention recommends at least annual human immunodeficiency virus (hiv) screening for men who have sex with men (msm), a large number of hiv infections among this population go unrecognized. we examined the association between disclosing to their medical providers (eg, physicians, nurses, physician assistants) same-sex attraction and self-reported hiv testing among msm in new york city, new york.200818625927
epidermodysplasia verruciformis-associated and genital-mucosal high-risk human papillomavirus dna are prevalent in nevus sebaceus of jadassohn.the hamartoma nevus sebaceus (ns) presents at birth or early childhood as a yellowish plaque characterized histologically by variable acanthosis, papillomatosis, sebaceus hyperplasia, and proliferations of adnexal structures. clinically apparent human papillomavirus (hpv) infection is also recognized by acanthosis and papillomatosis.200818638629
human immunodeficiency virus partner elicitation and notification in new york city: public health does it better.partner notification (pn) is an effective strategy to identify undiagnosed human immunodeficiency virus (hiv) infections and to likely reduce hiv transmission. whereas published literature has documented the benefits of provider referral for hiv pn, determination of the optimal provider--health department staff or community clinician--has not been previously studied. this study examined whether pn conducted by new york city (nyc) disease intervention specialists (dis) is more successful than pn ...200818641535
balamuthia mandrillaris, agent of amebic encephalitis: detection of serum antibodies and antigenic similarity of isolates by enzyme immunoassay.we report the development of an enzyme-linked immunosorbent assay (elisa) for detecting antibodies to balamuthia mandrillaris, a free-living ameba that is an etiologic agent of granulomatous amebic encephalitis (gae). as part of the california encephalitis project (cep), we have tested serum and cerebrospinal fluid (csf) samples from a subgroup of 130 hospitalized encephalitis patients (out of approximately 430 samples) over a 16-month period. case criteria were based on clinical, laboratory, an ...200818681845
detection and typing of enteroviruses from csf specimens from patients diagnosed with meningitis/encephalitis.human enteroviruses are the most common cause of viral meningitis. rapid enterovirus detection and identification is important in order to ruleout other causes of disease, initiate appropriate patient management and to aid in epidemiological investigations.200818692435
comparison of cyp1a2 and nat2 phenotypes between black and white smokers.the lower incidence rate of transitional cell carcinoma of the urinary bladder in blacks than in whites may be due to racial differences in the catalytic activity of enzymes that metabolize carcinogenic arylamines in tobacco smoke. to examine this, we compared cytochrome p4501a2 (cyp1a2) and n-acetyltransferase-2 activities (nat2) in black and white smokers using urinary caffeine metabolites as a probe for enzyme activity in a community-based study of 165 black and 183 white cigarette smokers. t ...200818703023
preparing for disaster: response matrices in the usa and uk.disasters, whether man-made or naturally occurring, require complex responses across multiple government agencies and private sector elements, including the media. these factors mandate that, for effective disaster management and because of the unpredictability of such events, response structures must be in place in advance, ready to be activated on short notice, with lines of responsibility clearly delineated and mechanisms for coordination of efforts already established. disaster response expe ...200818756376
genomic dna methylation among women in a multiethnic new york city birth cohort.one plausible mechanism for the environment to alter cancer susceptibility is through dna methylation. alterations in dna methylation can lead to genomic instability and altered gene transcription. genomic dna methylation levels have been inversely associated with age, suggesting that factors throughout life may be associated with declines in dna methylation. using information from a multiethnic new york city birth cohort (born between 1959 and 1963), we examined whether genomic dna methylation, ...200818768498
public reporting of quality data for stroke: is it measuring quality?public reporting of quality data is becoming more common and increasingly used to improve choices of patients, providers, and payers. we reviewed the scope and content of stroke data being reported to the public and how well it captures the quality of stroke care.200818772446
ssa. hiv-positive man denied disability benefits on appeal. 200818780473
borrelia burgdorferi genotype predicts the capacity for hematogenous dissemination during early lyme disease.lyme disease, the most common tickborne disease in the united states, is caused exclusively by borrelia burgdorferi sensu stricto in north america. the present study evaluated the genotypes of >400 clinical isolates of b. burgdorferi recovered from patients from suburban new york city with early lyme disease associated with erythema migrans; it is the largest number of borrelial strains from north america ever to be investigated.200818781866
detection of nosocomial influenza outbreaks in long-term care facilities through active laboratory surveillance in new york city. 200818786455
suppose they gave an epidemic and nobody came? 200818802852
celiac disease in african american children with type 1 diabetes mellitus in inner city brooklyn.there is a strong evidence for association between type 1 diabetes and celiac disease. up to 8% of patients with type1 diabetes have characteristic features of cd on small intestinal biopsy. type 1 diabetics who have hla dq2 or dq8 are at risk for cd. however most of this data is from studies conducted in europe, with mostly caucasian population. this study aims to identify the prevalence of celiac disease in african american children with type1 diabetes in inner city brooklyn, new york.200818806716
effect of timing of amantadine chemoprophylaxis on severity of outbreaks of influenza a in adult long-term care facilities.long-term care facilities (ltcfs) are vulnerable to outbreaks of influenza. there are limited data on the impact of antiviral chemoprophylaxis on the duration of outbreaks of influenza. we investigated the association of timely initiation of amantadine chemoprophylaxis on the duration and severity of outbreaks of influenza a in ltcfs in new york, new york.200818484879
effects of behavioral intervention on substance use among people living with hiv: the healthy living project randomized controlled study.reductions in substance use were examined in response to an intensive intervention with people living with human immunodeficiency virus (hiv) (plh).200818494840
standardization of spirometry in assessment of responders following man-made disasters: world trade center worker and volunteer medical screening program.spirometry is the most commonly used pulmonary function test to screen individuals for suspected lung disease. it is also used for screening workers with exposures to agents associated with pulmonary diseases. although the american thoracic society (ats) provides guidelines for spirometers and spirometry techniques, many factors are not standardized, so that results from individual pulmonary function laboratories vary substantially. these differences can create substantial difficulties in using ...200818500705
wtc medical monitoring and treatment program: comprehensive health care response in aftermath of disaster.the attack on the world trade center (wtc) on september 11th, 2001 exposed thousands of individuals to an unprecedented mix of chemicals, combustion products and micronized building materials. clinicians at the mount sinai irving selikoff center for occupational and environmental medicine, in partnership with affected stakeholder organizations, developed a medical screening program to evaluate the health status of workers and volunteers who spent time at the wtc site and thus sustained exposure ...200818500708
epidemiologic research on man-made disasters: strategies and implications of cohort definition for world trade center worker and volunteer surveillance program.studies of long-term health consequences of disasters face unique methodologic challenges. the authors focused on studies of the health of cleanup and recovery workers, who are often poorly enumerated at the outset and difficult to follow over time. comparison of the experience at the world trade center disaster with 4 past incidents of chemical and radiation releases at seveso, italy; bhopal, india; chernobyl, ukraine; and three mile island, usa, provided useful contrasts. each event had method ...200818500709
project viva: a multilevel community-based intervention to increase influenza vaccination rates among hard-to-reach populations in new york city.we sought to determine whether the work of a community-based participatory research partnership increased interest in influenza vaccination among hard-to-reach individuals in urban settings.200818511725
sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury.a single serum creatinine measurement cannot distinguish acute kidney injury from chronic kidney disease or prerenal azotemia.200818519927
the design and implementation of a multidisciplinary global health residency track at the mount sinai school of medicine.the mount sinai global health center established a new multidisciplinary global health residency track (ghrt) in 2006. the goal of the ghrt is to provide participants with a foundation in global health issues and population-based health care, a chance to develop basic research and public health skills in the field, and guidance for career development. the authors describe how the ghrt was created, present its structure, and discuss their experience implementing this new program. other selected g ...200818820521
do medical students know enough about smoking to help their future patients? assessment of new york city fourth-year medical students' knowledge of tobacco cessation and treatment for nicotine addiction.practicing physicians underutilize u.s. department of health and human services evidence-based approaches to nicotine addiction and treatment. few studies have assessed medical student knowledge in this area. this study examined new york city fourth-year medical students' knowledge of tobacco cessation and treatment of nicotine addiction.200818820533
new technologies in radiation therapy: ensuring patient safety, radiation safety and regulatory issues in radiation oncology.new technologies such as intensity modulated and image guided radiation therapy, computer controlled linear accelerators, record and verify systems, electronic charts, and digital imaging have revolutionized radiation therapy over the past 10-15 y. quality assurance (qa) as historically practiced and as recommended in reports such as american association of physicists in medicine task groups 40 and 53 needs to be updated to address the increasing complexity and computerization of radiotherapy eq ...200818849700
salt marsh as culex salinarius larval habitat in coastal new york.culex salinarius is considered one of the most likely bridge vectors involved in the human transmission cycle of west nile virus (wnv) and eastern equine encephalomyelitis virus (eeev) in the northeastern usa. the larval habitats of this species in the coastal region of new york state are currently poorly known. between 2005 and 2007, a larval survey was carried out to identify and characterize possible larval habitats in suffolk county, encompassing natural and man-made freshwater wetlands, art ...200818939687
increased recognition of powassan encephalitis in the united states, 1999-2005.powassan virus (powv) disease is a rare human disease caused by a tick-borne encephalitis group flavivirus maintained in a transmission cycle between ixodes cookei and other ixodid ticks and small and medium-sized mammals. during 1958-1998, only 27 powv disease cases (mostly powassan encephalitis) were reported from eastern canada and the northeastern united states (average, 0.7 cases per year). during 1999-2005, nine cases (described herein) of serologically confirmed powv disease were reported ...200818959500
preventing cervical cancer : overviews of the national breast and cervical cancer early detection program and 2 us immunization programs.three federal programs with the potential to reduce cervical cancer incidence, morbidity, and mortality, especially among underserved populations, are administered by the centers for disease control and prevention (cdc): the national breast and cervical cancer early detection program (nbccedp), the vaccines for children (vfc) program, and the section 317 immunization grant program. the nbccedp provides breast and cervical cancer screening and diagnostic services to uninsured and underinsured wom ...200818980296
attitudes toward menopause in hiv-infected and at-risk women.to study attitudes toward menopause in women with or at risk of human immunodeficiency virus (hiv) aged 35 to 60 in new york city, ny, usa.200818982926
comparative analysis of distribution and abundance of west nile and eastern equine encephalomyelitis virus vectors in suffolk county, new york, using human population density and land use/cover data.five years of cdc light trap data from suffolk county, ny, were analyzed to compare the applicability of human population density (hpd) and land use/cover (luc) classification systems to describe mosquito abundance and to determine whether certain mosquito species of medical importance tend to be more common in urban (defined by hpd) or residential (defined by luc) areas. eleven study sites were categorized as urban or rural using u.s. census bureau data and by luc types using geographic informa ...200818533453
landscape ecology of eastern coyotes based on large-scale estimates of abundance.since their range expansion into eastern north america in the mid-1900s, coyotes (canis latrans) have become the region's top predator. although widespread across the region, coyote adaptation to eastern forests and use of the broader landscape are not well understood. we studied the distribution and abundance of coyotes by collecting coyote feces from 54 sites across a diversity of landscapes in and around the adirondacks of northern new york. we then genotyped feces with microsatellites and fo ...200818536259
risk factors for delayed initiation of medical care after diagnosis of human immunodeficiency virus.the full benefit of timely diagnosis of human immunodeficiency virus (hiv) infection is realized only if there is timely initiation of medical care. we used routine surveillance data to measure time to initiation of care in new york city residents diagnosed as having hiv by positive western blot test in 2003.200818541826
integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including drosha.copy number gains and amplifications are characteristic feature of cervical cancer (cc) genomes for which the underlying mechanisms are unclear. these changes may possess oncogenic properties by deregulating tumor-related genes. gain of short arm of chromosome 5 (5p) is the most frequent karyotypic change in cc.200818559093
false-positive oral fluid rapid hiv tests--new york city, 2005-2008.the new york city department of health and mental hygiene (nyc dohmh) operates 10 sexually transmitted disease (std) walk-in clinics offering various free services, including confidential or anonymous testing for human immunodeficiency virus (hiv). in january 2004, the std clinics introduced on-site rapid hiv testing of finger-stick whole-blood specimens using the oraquick(r) brand test (orasure technologies, bethlehem, pennsylvania). in march 2005, the clinics replaced finger-stick whole-blood ...200818566566
risk behaviors in a rural community with a known point-source exposure to chronic wasting disease.the emergence and continuing spread of chronic wasting disease (cwd) in cervids has now reached 14 u.s. states, two canadian provinces, and south korea, producing a potential for transmission of cwd prions to humans and other animals globally. in 2005, cwd spread for the first time from the midwest to more densely populated regions of the east coast. as a result, a large cohort of individuals attending a wild game feast in upstate new york were exposed to a deer that was subsequently confirmed p ...200818577220
ssi. denial of disability benefits affirmed for hiv-positive man. 200818584799
west nile virus activity--united states, 2007.west nile virus (wnv) is the leading cause of arboviral encephalitis in the united states. originally identified in africa in 1937, wnv was first detected in the western hemisphere in 1999 in new york city. since then, wnv has caused seasonal epidemics of febrile illness and neurologic disease in the united states. this report summarizes national wnv surveillance data for 2007. wnv transmission to humans or animals expanded into 19 counties that had not reported transmission previously and recur ...200818600197
polybrominated diphenyl ethers (pbdes) in biota representing different trophic levels of the hudson river, new york: from 1999 to 2005.it has been hypothesized that a principal route of human exposure to polybrominated diphenyl ethers (pbdes), used as flame retardants, is through fish consumption. between 1999 and 2005 pbde-47, -99, -100, -153, and -154 were analyzed in 3797 biological samples of 33 species of the hudson river, new york. approximately 98.4% of the samples contained pbdes between 0.5 and 37 169 ng g(-1) lipid, with a median concentration of 772 ng g(-1) lipid. yearly median sigmapbde concentrations fluctuated. s ...200818605551
availability of trivalent inactivated influenza vaccine to parents of neonatal intensive care unit patients and its effect on the healthcare worker vaccination rate.trivalent inactivated influenza vaccine (tiv) is indicated for healthcare workers (hcws); however, the vaccination rate in this population is estimated at 35%. we implemented a program for the administration of tiv, targeted at parents of neonatal intensive care unit (nicu) patients.200818462142
population prevalence of reported and unreported hiv and related behaviors among the household adult population in new york city, 2004.surveillance for hiv likely underestimates infection among the general population: 25% of us residents are estimated to be unaware of their hiv infection.200818097231
nicu lactation consultant increases percentage of outborn versus inborn babies receiving human milk.to determine the effect of a dedicated lactation consultant (lc) on the percentage of neonates receiving any human milk in the neonatal intensive care unit (nicu) and at discharge over time.200818094704
influenza-testing and antiviral-agent prescribing practices--connecticut, minnesota, new mexico, and new york, 2006-07 influenza season.influenza is a major cause of morbidity and mortality in the united states, with an average of 36,000 deaths attributed to the disease annually. patients with influenza-like illness (ili) often are evaluated by their primary-care physicians (pcps). antiviral therapy initiated within 48 hours of ili symptom onset can shorten the course of influenza illness; antiviral therapy also is used as chemoprophylaxis for influenza, particularly in institutions and communities. early laboratory diagnosis an ...200818219266
assessment of interactions between pah exposure and genetic polymorphisms on pah-dna adducts in african american, dominican, and caucasian mothers and newborns.polycyclic aromatic hydrocarbons (pah) are widespread pollutants commonly found in air, food, and drinking water. benzo[a]pyrene is a well-studied representative pah found in air from fossil fuel combustion and a transplacental carcinogen experimentally. pahs bind covalently to dna to form dna adducts, an indicator of dna damage, and an informative biomarker of potential cancer risk. associations between pah-dna adduct levels and both cancer risk and developmental deficits have been seen in prev ...200818268125
factors associated with the prevalence and incidence of trichomonas vaginalis infection among african american women in new york city who use drugs.trichomoniasis vaginalis, the most prevalent nonviral sexually transmitted infection, is associated with negative reproductive outcomes and increased hiv transmission and may be overrepresented among african americans.200818275272
evaluation of pathways for release of rift valley fever virus into domestic ruminant livestock, ruminant wildlife, and human populations in the continental united states.to evaluate the feasibility for rift valley fever virus (rvfv) to enter the continental united states by various routes as well as to identify states in which domestic and wild ruminant and human populations would be most vulnerable to exposure to rvfv.200818279085
breastfeeding and infant illness in low-income, minority women: a prospective cohort study of the dose-response relationship.the authors' objective was to determine whether cumulative weekly breastfeeding duration by 13 weeks was associated with infant otitis media, respiratory and gastrointestinal illness, and total illness visits up to 12 months. the authors performed a secondary analysis of data from a randomized clinical trial of low-income, primarily hispanic and black women enrolled from 2 medical center affiliated clinics. "breastfeeding sensitive" (bfs) outpatient and emergency room (er) visit data for the abo ...200818281352
us civilian smallpox preparedness and response program, 2003.variola virus, the cause of smallpox disease, has been deemed a possible bioterrorism agent. since november 2001, federal, state, and local public health partners implemented activities to prepare for a possible smallpox outbreak. the centers for disease control and prevention (cdc) produced and delivered training and educational materials for smallpox preparedness in many formats, developed detailed smallpox vaccine information statements about vaccine contraindications and vaccination site car ...200818284355
gender of pediatric recombinant human growth hormone recipients in the united states and globally.gender disparities were found in reports of early pediatric recombinant human gh (rhgh) use in the united states. with rhgh entering its third decade, we sought to examine u.s. gender-based treatment patterns and how these patterns compare with that of other countries.200818334582
markers for hepatitis a, b and c in methadone maintained patients: an unexpectedly high co-infection with silent hepatitis b.to determine the prevalence of hepatitis a, b and c viruses in patients attending a methadone maintenance clinic in new york city.200818339114
greater drug injecting risk for hiv, hbv, and hcv infection in a city where syringe exchange and pharmacy syringe distribution are illegal.comparing drug-injecting risk between cities that differ in the legality of sterile syringe distribution for injection drug use provides a natural experiment to assess the efficacy of legalizing sterile syringe distribution as a structural intervention to prevent human immunodeficiency virus (hiv) and other parenterally transmitted infections among injection drug users (idus). this study compares the parenteral risk for hiv and hepatitis b (hbv) and c (hcv) infection among idus in newark, nj, us ...200818340537
voices from the battlefield: reports of the daily experiences of urban black mothers.there are persistent disparities in maternal child health in the united states. in this study i used an ethnographic design to portray the everyday lives of 130 black, low-income, urban mothers. the women described daily battles related to a lack of material and human resources. to deal with these challenges, they assumed the role of soldiers, developed new tactical maneuvers, trusted in god for justice, shared their resources with their comrades, took short-lived breaks when they were wounded i ...200818350419
polymorphisms in rad51, xrcc2, and xrcc3 are not related to breast cancer risk. 200818398049
seroprevalence of herpes simplex virus type 2 and characteristics associated with undiagnosed infection: new york city, 2004.herpes simplex virus type 2 (hsv-2) infection is associated with substantial morbidity and increased risk for human immunodeficiency virus acquisition. we describe hsv-2 seroprevalence in adult new yorkers, and examine the relationship between select characteristics, infection, and diagnosis.200818418295
the genomic and epidemiological dynamics of human influenza a virus.the evolutionary interaction between influenza a virus and the human immune system, manifest as 'antigenic drift' of the viral haemagglutinin, is one of the best described patterns in molecular evolution. however, little is known about the genome-scale evolutionary dynamics of this pathogen. similarly, how genomic processes relate to global influenza epidemiology, in which the a/h3n2 and a/h1n1 subtypes co-circulate, is poorly understood. here through an analysis of 1,302 complete viral genomes ...200818418375
primary vaccine failure after 1 dose of varicella vaccine in healthy children.universal immunization of young children with 1 dose of varicella vaccine was recommended in the united states in 1995, and it has significantly decreased the incidence of chickenpox. outbreaks of varicella, however, are reported among vaccinated children. although vaccine effectiveness has usually been 85%, rates as low as 44% have been observed. whether this is from primary or secondary vaccine failure-or both-is unclear. we tested serum samples from 148 healthy children immunized against vari ...200818419532
a new addition to the mosquito fauna of the suny oneonta biological field station, otsego county, new york.an apparent natural introduction and establishment of a population of anopheles walkeri into an ecological research site is documented. likelihood of introduction by human activity is discussed.200818437821
clinical characterization of human metapneumovirus infection among patients with cancer.human metapneumovirus is a recently discovered rna virus that typically causes respiratory disease in children. it has been linked to severe lower airway disease in hematopoietic stem cell and solid-organ transplant recipients. hmpv infection in a large population of patients with underlying cancer and varying degrees of immunosuppression has not been reported. we sought to characterize hmpv infection in patients with cancer.200819027169
co-infection of hepatitis b and hepatitis c virus in human immunodeficiency virus-infected patients in new york city, united states.to study the prevalence and risk factors associated with triple infection with human immunodeficiency virus (hiv)/hepatitis b virus (hbv)/hepatitis c virus (hcv) in an urban clinic population.200819034972
receptor status and ethnicity of indigent patients with breast cancer in new york city.previous studies have suggested racial differences in breast cancer hormonal receptor status, reflecting possible differences in tumor biology. however, racial differences in socioeconomic status and reproductive risk factors may influence receptor status. we investigated this issue, studying a racially diverse but socioeconomically homogeneous cohort of 215 patients with breast cancer at a new york public hospital from january 1, 1999, through december 31, 2003. we analyzed positive findings fo ...200819075177
enhancing accurate data collection in mass fatality kinship identifications: lessons learned from hurricane katrina.a mass fatality dna identification effort is a complex process in which direct matching and kinship analysis is used for identifying human remains. kinship dna identification is an important tool in the identification process in which victim's dna profiles are compared to the profiles of "known" biologically related reference samples. experience from the 9/11 world trade center dna identification efforts showed that forms used to record biological relationships are important and that inaccuratel ...200819083848
association of adhd, tics, and anxiety with dopamine transporter (dat1) genotype in autism spectrum disorder.autism spectrum disorder (asd) is associated with high rates of psychiatric disturbance to include attention-deficit/hyperactivity disorder (adhd), tic disorder, and anxiety disorders. the aim of the present study was to examine the association between a variable number tandem repeat (vntr) functional polymorphism located in the 3'-untranslated region of the dopamine transporter gene (dat1) and the severity of these symptoms as well as the association between the dat1 ddei polymorphism and sever ...200819120712
prevalence of influenza vaccination and pneumococcal vaccination in elderly and high-risk patients seen in a university general medicine clinic.charts of 240 unselected patients (149 women and 91 men), mean age 74 +/- 7 years (range, 64-95 years), seen in a university general medicine clinic at westchester medical center/new york medical college between april 2004 and april 2007 were reviewed for the use of influenza vaccination and pneumococcal vaccination. of the 240 patients, 108 (45%) had cardiovascular disease, 183 (76%) had hypertension, 70 (29%) had diabetes mellitus, 32 (13%) had chronic pulmonary disease, 30 (13%) had cancer, 2 ...200819127136
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