Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| lactobacillus rhamnosus rc007 intended for feed additive: immune-stimulatory properties and ameliorating effects on tnbs-induced colitis. | lactobacillus rhamnosus rc007 is a potential probiotic bacterium that can exert beneficial effects as supplement for animal feed, by improving the immune status in healthy host, and by providing therapeutic benefits to infected/inflamed animals. the aim of the present work was to evaluate in vivo the beneficial properties of l. rhamnosus rc007, intended for animal feed, when administered to healthy and trinitro-benzene-sulfonic-acid (tnbs) colitis induced balb/c mice. the administration of l. rh ... | 2016 | 27048833 |
| antiproliferative effects on colon adenocarcinoma cells induced by co-administration of vitamin k1 and lactobacillus rhamnosus gg. | vitamin k (vk), an essential nutrient associated with the clotting cascade, has also been demonstrated to have anticancer properties in various cancer cells including colon cancer cells. also probiotics have gained interest as potential anticancer agents. among them, lactobacillus rhamnosus gg (l.gg) has been shown to inhibit cell proliferation and polyamine biosynthesis as well as to induce apoptosis in different human gastrointestinal cancer cells. nevertheless, the exact mechanisms involved i ... | 2016 | 27035094 |
| restoration gaps needed to exceed a threshold size to impede sealed lesion arrest in vitro. | after selective excavation, bacteria are sealed beneath restorations. leaking restorations could maintain carbohydrate-supply, leading to lesion progression and pulp damage. it is unclear if fluid (and thereby carbohydrate) exchange occurs through any interfacial gaps, or if such exchange only occurs in case gaps exceed a certain threshold size. we investigated how different restoration gap sizes impact on survival of sealed bacterial in vitro. | 2016 | 27026078 |
| improvement of l-lactic acid productivity from sweet sorghum juice by repeated batch fermentation coupled with membrane separation. | in order to efficiently produce l-lactic acid from non-food feedstocks, sweet sorghum juice (ssj), which is rich of fermentable sugars, was directly used for l-lactic acid fermentation by lactobacillus rhamnosus la-04-1. a membrane integrated repeated batch fermentation (mirb) was developed for productivity improvement. high-cell-density fermentation was achieved with a final cell density (od620) of 42.3, and the ccr effect was overcomed. when ssj (6.77gl(-1) glucose, 4.51gl(-1) fructose and 50. ... | 2016 | 27023384 |
| protective effects of lactobacillus rhamnosus gg against dyslipidemia in high-fat diet-induced obese mice. | recent reports suggest that gut microbiota can be a major determinant of dyslipidemia and non-alcoholic fatty liver disease (nafld) and its modulation by treating probiotics is a valid strategy to exert a protective effect. in this study, high-fat diet (hfd)-fed mice were orally administrated with lactobacillus rhamnosus gg (lgg) for 13 weeks. significant reductions in the weights of the liver, mesenteric and subcutaneous adipose tissues were observed in lgg-treated hfd-fed mice compared to lgg- ... | 2016 | 27018382 |
| lactobacillus rhamnosus gg intake modifies preschool children's intestinal microbiota, alleviates penicillin-associated changes, and reduces antibiotic use. | antibiotic use is considered among the most severe causes of disturbance to children's developing intestinal microbiota, and frequently causes adverse gastrointestinal effects ranging from mild and transient diarrhoea to life-threatening infections. probiotics are commonly advocated to help in preventing antibiotic-associated gastrointestinal symptoms. however, it is currently unknown whether probiotics alleviate the antibiotic-associated changes in children's microbiota. furthermore, it is not ... | 2016 | 27111772 |
| fermented milk with probiotic lactobacillus rhamnosus s1k3 (mtcc5957) protects mice from salmonella by enhancing immune and nonimmune protection mechanisms at intestinal mucosal level. | we investigated the mechanism by which an indian indigenous probiotic culture, lactobacillus rhamnosus s1k3, could overcome the pathogenic strain salmonella enterica with an emphasis on the response at the intestinal mucosal level after long-term (30days) consumption. s1k3 was able to produce antimicrobial compounds against the pathogens. the probiotic adhered strongly to intestinal epithelium and maintained its integrity in presence of salmonella through stimulation of tight junction and antimi ... | 2016 | 27012622 |
| clinical effects of lactobacillus rhamnosus in non-surgical treatment of chronic periodontitis: a randomized placebo-controlled trial with 1-year follow-up. | probiotics are living microorganisms that provide beneficial effects for the host when administered in proper quantities. the aim of this double-masked placebo-controlled parallel-arm randomized clinical trial is to evaluate the clinical effects of a lactobacillus rhamnosus sp1-containing probiotic sachet as an adjunct to non-surgical therapy. | 2016 | 26944407 |
| lactobacillus sepsis and probiotic therapy in newborns: two new cases and literature review. | many term and preterm infants are commonly supplemented with probiotics to prevent adverse effects of antibiotic administration and necrotizing enterocolitis and they are believed to be safe. however, the supplementation with lactobacillus rhamnosus gg has been associated with the development of sepsis with a cause-effect relationship in six newborns and children. in this study, we report two further cases and discuss the emerging issue of probiotic supplementation safety in neonates. we conclud ... | 2016 | 26929865 |
| the effects of a probiotic formulation (lactobacillus rhamnosus and l. helveticus) on developmental trajectories of emotional learning in stressed infant rats. | recently, scientific interest in the brain-gut axis has grown dramatically, particularly with respect to the link between gastrointestinal and psychiatric dysfunction. however, the role of gut function in early emotional dysregulation is yet to be examined, despite the prevalence and treatment resistance of early-onset psychiatric disorders. the present studies utilized a developmental rodent model of early-life stress (els) to explore this gap. rats were exposed to maternal separation (ms) on p ... | 2016 | 27244232 |
| characterization of a new cell envelope proteinase prtp from lactobacillus rhamnosus cgmcc11055. | cell envelope proteinases (ceps) play essential roles in lactic acid bacteria growth in milk and health-promoting properties of fermented dairy products. the genome of lactobacillus rhamnosus cgmcc11055 possesses two putative cep genes prtp and prtr2, and the prtp displays the distinctive domain organization from prtr2 reported. the prtp was purified and biochemically characterized. the results showed that the optimal activity occurred at 44 °c, ph 6.5. p-amidinophenylmethylsulfonyl fluoride obv ... | 2016 | 27585760 |
| the variable regions of lactobacillus rhamnosus genomes reveal the dynamic evolution of metabolic and host-adaptation repertoires. | lactobacillus rhamnosus is a diverse gram-positive species with strains isolated from different ecological niches. here, we report the genome sequence analysis of 40 diverse strains of l. rhamnosus and their genomic comparison, with a focus on the variable genome. genomic comparison of 40 l. rhamnosus strains discriminated the conserved genes (core genome) and regions of plasticity involving frequent rearrangements and horizontal transfer (variome). the l. rhamnosus core genome encompasses 2,164 ... | 2016 | 27358423 |
| lactobacillus rhamnosus gg activation of dendritic cells and neutrophils depends on the dose and time of exposure. | this study evaluates the ability of lactobacillus rhamnosus gg (lgg) to activate dc and neutrophils and modulate t cell activation and the impact of bacterial dose on these responses. murine bone marrow derived dc or neutrophils were stimulated with lgg at ratios of 5 : 1, 10 : 1, and 100 : 1 (lgg : cells) and dc maturation (cd40, cd80, cd86, cd83, and mhc class ii) and cytokine production (il-10, tnf-α, and il-12p70) were examined after 2 h and 18 h coculture and compared to the ability of bcg ... | 2016 | 27525288 |
| epigenetic features of foxp3 in children with cow's milk allergy. | dna methylation of the th1 and th2 cytokine genes is altered during cow's milk allergy (cma). forkhead box transcription factor 3 (foxp3) is essential for the development and function of regulatory t cells (tregs) and is involved in oral tolerance acquisition. we assessed whether tolerance acquisition in children with ige-mediated cma is associated with dna demethylation of the treg-specific demethylated region (tsdr) of foxp3. | 2016 | 27525046 |
| probiotic lactobacillus rhamnosus reduces organophosphate pesticide absorption and toxicity to drosophila melanogaster. | organophosphate pesticides used in agriculture can pose health risks to humans and wildlife. we hypothesized that dietary supplementation with lactobacillus, a genus of commensal bacteria, would reduce absorption and toxicity of consumed organophosphate pesticides (parathion and chlorpyrifos [cp]). several lactobacillus species were screened for toleration of 100 ppm of cp or parathion in mrs broth based on 24-h growth curves. certain lactobacillus strains were unable to reach stationary-phase c ... | 2016 | 27520820 |
| probiotics: prevention of severe pneumonia and endotracheal colonization trial-prospect: a pilot trial. | probiotics are live microorganisms that may confer health benefits when ingested. randomized trials suggest that probiotics significantly decrease the incidence of ventilator-associated pneumonia (vap) and the overall incidence of infection in critically ill patients. however, these studies are small, largely single-center, and at risk of bias. the aim of the prospect pilot trial was to determine the feasibility of conducting a larger trial of probiotics to prevent vap in mechanically ventilated ... | 2016 | 27480757 |
| systematic exploration of the glycoproteome of the beneficial gut isolate lactobacillus rhamnosus gg. | glycoproteins form an interesting class of macromolecules involved in bacterial-host interactions, but they are not yet widely explored in gram-positive and beneficial species. here, an integrated and widely applicable approach was followed to identify putative bacterial glycoproteins, combining proteome fractionation with 2d protein and glycostained gels and lectin blots. this approach was validated for the microbiota isolate lactobacillus rhamnosus gg. the approach resulted in a list of putati ... | 2016 | 27463506 |
| thermal aggregation of calcium-fortified skim milk enhances probiotic protection during convective droplet drying. | probiotic bacteria have been reported to confer benefits on hosts when delivered in an adequate dose. spray-drying is expected to produce dried and microencapsulated probiotic products due to its low production cost and high energy efficiency. the bottleneck in probiotic application addresses the thermal and dehydration-related inactivation of bacteria during process. a protective drying matrix was designed by modifying skim milk with the principle of calcium-induced protein thermal aggregation. ... | 2016 | 27420726 |
| relative cost-effectiveness of using an extensively hydrolyzed casein formula containing the probiotic lactobacillus rhamnosus gg in managing infants with cow's milk allergy in poland. | to estimate the cost-effectiveness of using an extensively hydrolyzed casein formula (ehcf) containing the probiotic lactobacillus rhamnosus gg (ehcf + lgg; nutramigen lgg) as an initial treatment for cow's milk allergy compared with ehcf alone and amino acid formulas (aaf) in poland from the perspective of the polish national health fund (narodowy fundusz zdrowia [nfz]) and parents. | 2016 | 27418845 |
| new insights about pilus formation in gut-adapted lactobacillus rhamnosus gg from the crystal structure of the spaa backbone-pilin subunit. | thus far, all solved structures of pilin-proteins comprising sortase-assembled pili are from pathogenic genera and species. here, we present the first crystal structure of a pilin subunit (spaa) from a non-pathogen host (lactobacillus rhamnosus gg). spaa consists of two tandem cnab-type domains, each with an isopeptide bond and e-box motif. intriguingly, while the isopeptide bond in the n-terminal domain forms between lysine and asparagine, the one in the c-terminal domain atypically involves as ... | 2016 | 27349405 |
| fermented rice bran prevents atopic dermatitis in dncb-treated nc/nga mice. | the fermentation of natural plants has a favorable effect on the functional and biological activities of living systems. these include anti-oxidative, anti-inflammatory, and anti-platelet aggregation activities. this is attributed to the chemical conversion of the parent plants to functional constituents, which show more potent biological activity. in our study, rice bran along with oriental medicinal plants (angelicae gigantis, cnidium officinale, artemisia princeps, and camellia sinensis) was ... | 2016 | 27323667 |
| lactobacillus rhamnosus gg modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. | a better understanding of mechanisms underlying dose-effects of probiotics in their applications as treatments of intestinal infectious or inflammatory diseases and as vaccine adjuvant is needed. in this study, we evaluated the modulatory effects of lactobacillus rhamnosus gg (lgg) on transplanted human gut microbiota (hgm) and on small intestinal immune cell signaling pathways in gnotobiotic pigs vaccinated with an oral attenuated human rotavirus (atthrv) vaccine. | 2016 | 27301272 |
| effectiveness of a combination of cranberries, lactobacillus rhamnosus, and vitamin c for the management of recurrent urinary tract infections in women: results of a pilot study. | urinary tract infections (utis) are common in women and many patients with recurrent utis do not eradicate the condition albeit being treated with multiple courses of antibiotics. the use of nutritional supplements might reduce the risk of recurrent utis. however, the role of supplements taken as single agents appears to be limited. we hypothesized that a combination of cranberries, lactobacillus rhamnosus, and vitamin c might produce a clinical benefit due to their additive or synergistic effec ... | 2016 | 27283213 |
| the probiotics in pregnancy study (pip study): rationale and design of a double-blind randomised controlled trial to improve maternal health during pregnancy and prevent infant eczema and allergy. | worldwide there is increasing interest in the manipulation of human gut microbiota by the use of probiotic supplements to modify or prevent a range of communicable and non-communicable diseases. probiotic interventions administered during pregnancy and breastfeeding offer a unique opportunity to influence a range of important maternal and infant outcomes. the aim of the probiotics in pregnancy study (pip study) is to assess if supplementation by the probiotic lactobacillus rhamnosus hn001 admini ... | 2016 | 27255079 |
| radiographic, antibacterial and bond-strength effects of radiopaque caries tagging. | selectively excavated carious lesions remain radiographically detectable. radiopaque tagging could resolve the resulting diagnostic uncertainty. we aimed to evaluate if tagging depends on lesions depths, is antibacterial, or affects dentin bond-strengths. artificial lesions (depth-range: 152-682 μm, n = 34/group) were induced in human dentin samples, evaluated using wavelength-independent microradiography, treated with one of two tagging materials (70% sncl2, 30% snf2) and re-evaluated. to evalu ... | 2016 | 27251174 |
| [experience of the rational antibacterial therapy conduction in treatment of children for the burn trauma]. | abstract the principles of rational antibacterial therapy in children for the burn trauma were analyzed. the results of the completed treatment of 808 children for the burn trauma in a combustiological department of municipal clinical hospital of city of zaporozhye were studied. in 326 (40.3%) children antibacterial therapy was conducted, including one antibiotic--in 268 (82.2%), two and more--in 37 (11.3%). the preparations were prescribed empirically, taking into account bacteriological profil ... | 2016 | 27244927 |
| probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish. | the gut microbiota plays a crucial role in the bi-directional gut-brain axis, a communication that integrates the gut and central nervous system (cns) activities. animal studies reveal that gut bacteria influence behaviour, brain-derived neurotrophic factor (bdnf) levels and serotonin metabolism. in the present study, we report for the first time an analysis of the microbiota-gut-brain axis in zebrafish (danio rerio). after 28 days of dietary administration with the probiotic lactobacillus rhamn ... | 2016 | 27416816 |
| effect of lactobacillus rhamnosus gg and vitamin d supplementation on the immunologic effectiveness of grass-specific sublingual immunotherapy in children with allergy. | an important issue in sublingual immunotherapy (slit) is how to improve efficacy. | 2016 | 27401319 |
| immunomodulation of lactobacillus rhamnosus gg (lgg)-derived soluble factors on antigen-presenting cells of healthy blood donors. | lactobacillus rhamnosus gg (lgg) cells have been shown to promote type-1 immune responsiveness; however knowledge of immunomodulation of soluble factors secreted by lgg is limited. this is the first study to investigate whether lgg soluble factors promote a comparable immune responsiveness as the bacterial cells. both treatments - lgg conditioned medium with (cm + lgg) or without (cm) lgg cells, in this study increased expression of several toll-like receptors (tlrs) in all studied cell types an ... | 2016 | 26961406 |
| lactobacillus sepsis following a laparotomy in a preterm infant: a note of caution. | probiotics for preterm infants have been shown to reduce the incidence of necrotising enterocolitis and all-cause mortality in a recent meta-analysis. it has been argued, however, that some of these results may not be applicable to specific subgroups, e.g. infants with a birth weight of <1,000 g. the specific role of probiotics in improving health outcomes in preterm and term infants following intestinal surgery is not well defined. we report a case of a premature infant diagnosed with late-onse ... | 2016 | 26780534 |
| using food and nutritional strategies to induce tolerance in food-allergic children. | food allergy is an important and increasing public health problem worldwide, affecting predominantly infants and young children. there is an urgent need to develop effective treatment strategies to restore oral tolerance in food-allergic individuals. among diverse research approaches, those involving native or heat-modified food proteins are most advanced and are currently being evaluated in clinical trials. extensively heated (baked) milk and egg diets have already been adopted in clinical prac ... | 2016 | 27088331 |
| polymorphisms, chromosomal rearrangements, and mutator phenotype development during experimental evolution of lactobacillus rhamnosus gg. | lactobacillus rhamnosus gg is a lactic acid bacterium widely marketed by the food industry. its genomic analysis led to the identification of a gene cluster encoding mucus-binding spacba pili, which is located in a genomic island enriched in insertion sequence (is) elements. in the present study, we analyzed by genome-wide resequencing the genomic integrity of l. rhamnosus gg in four distinct evolutionary experiments conducted for approximately 1,000 generations under conditions of no stress or ... | 2016 | 27084020 |
| studies on anti-inflammatory and analgesic properties of lactobacillus rhamnosus in experimental animal models. | nonsteroidal anti-inflammatory drugs (nsaids) are frequently used for the treatment of inflammatory diseases. however, constant use of nsaid may lead to some side effects like gastrointestinal ulcers, bleeding and renal disorders. this study evaluates analgesic and anti-inflammatory activities of lactobacillus rhamnosus in female wistar rats. | 2016 | 27078675 |
| isolation, identification, and evaluation of novel probiotic strains isolated from feces of breast-fed infants. | to isolate, identify, and evaluate the probiotic properties of lactic acid bacteria (lab) isolated from the feces of breast-fed infants. | 2016 | 26817236 |
| immobilization of lactobacillus rhamnosus in mesoporous silica-based material: an efficiency continuous cell-recycle fermentation system for lactic acid production. | lactic acid bacteria immobilization methods have been widely used for lactic acid production. until now, the most common immobilization matrix used is calcium alginate. however, ca-alginate gel disintegrated during lactic acid fermentation. to overcome this deficiency, we developed an immobilization method in which lactobacillus rhamnosus cells were successfully encapsulated into an ordered mesoporous silica-based material under mild conditions with a high immobilization efficiency of 78.77% by ... | 2016 | 26803707 |
| whole-cell biocatalysis for producing ginsenoside rd from rb1 using lactobacillus rhamnosus gg. | ginsenosides are the major active ingredients in ginseng used for human therapeutic plant medicines. one of the most well-known probiotic bacteria among the various strains on the functional food market is lactobacillus rhamnosus gg. biocatalytic methods using probiotic enzymes for producing deglycosylated ginsenosides such as rd have a growing significance in the functional food industry. the addition of 2% cellobiose (w/v) to glucose-free de man-rogosa-sharpe broths notably induced β-glucosida ... | 2016 | 27012233 |
| lactobacillus rhamnosus could inhibit porphyromonas gingivalis derived cxcl8 attenuation. | an increasing body of evidence suggests that the use of probiotic bacteria is a promising intervention approach for the treatment of inflammatory diseases with a polymicrobial etiology. p. gingivalis has been noted to have a different way of interacting with the innate immune response of the host compared to other pathogenic bacteria, which is a recognized feature that inhibits cxcl8 expression. | 2016 | 27008259 |
| human rhinovirus in experimental infection after peroral lactobacillus rhamnosus gg consumption, a pilot study. | data has emerged on possible beneficial effects of probiotics in respiratory tract viral infections, but it is unclear if the promising positive effects evidenced are due to a reduced viral load during infections. the aims of this work were to investigate the effect of peroral probiotic lactobacillus rhamnosus gg (american type culture collection [atcc], accession no. 53103) consumption on human rhinovirus (hrv) load in nasopharyngeal lavage samples in experimental hrv infection, and to correlat ... | 2016 | 26990147 |
| therapeutic effect of tyndallized lactobacillus rhamnosus idcc 3201 on atopic dermatitis mediated by down-regulation of immunoglobulin e in nc/nga mice. | the therapeutic effect of oral administration of lactobacillus rhamnosus idcc 3201 tyndallizate (rht3201) on atopic dermatitis (ad)-like skin lesions in nc/nga mice were investigated. after induction of dermatitis in nc/nga mice with house-dust mite extract, each group was fed rht3201 with 1 × 10(8) , 1 × 10(9) , or 1 × 10(10) cells orally once a day for 8 weeks. dermatitis scores and frequency of scratching were improved by oral feeding with rht3201. in contrast to the control group, rht3201-fe ... | 2016 | 27240551 |
| microencapsulation of lactobacillus rhamnosus gg by transglutaminase cross-linked soy protein isolate to improve survival in simulated gastrointestinal conditions and yoghurt. | microencapsulation is an effective way to improve the survival of probiotics in simulated gastrointestinal (gi) conditions and yoghurt. in this study, microencapsulation of lactobacillus rhamnosus gg (lgg) was prepared by first cross-linking of soy protein isolate (spi) using transglutaminase (tgase), followed by embedding the bacteria in cross-linked spi, and then freeze-drying. the survival of microencapsulated lgg was evaluated in simulated gi conditions and yoghurt. the results showed that a ... | 2016 | 27228279 |
| probiotic gut microbiota isolate interacts with dendritic cells via glycosylated heterotrimeric pili. | mapping of the microbial molecules underlying microbiota-host interactions is key to understand how microbiota preserve mucosal homeostasis. a pivotal family of such bacterial molecules are pili. pili are proteinaceous cell wall appendages with a well-documented role in adhesion, whilst their role in immune interaction with the host is less established. gram-positive pili are often posttranslationally modified by sortase-specific cleavage reactions and the formation of intramolecular peptide bon ... | 2016 | 26985831 |
| secretory iga in complex with lactobacillus rhamnosus potentiates mucosal dendritic cell-mediated treg cell differentiation via tlr regulatory proteins, raldh2 and secretion of il-10 and tgf-β. | the importance of secretory iga in controlling the microbiota is well known, yet how the antibody affects the perception of the commensals by the local immune system is still poorly defined. we have previously shown that the transport of secretory iga in complex with bacteria across intestinal microfold cells results in an association with dendritic cells in peyer's patches. however, the consequences of such an interaction on dendritic cell conditioning have not been elucidated. in this study, w ... | 2016 | 26972771 |
| effects of prebiotic oligosaccharides consumption on the growth and expression profile of cell surface-associated proteins of a potential probiotic lactobacillus rhamnosus fsmm15. | to investigate carbohydrate preference of a potential probiotic, lactobacillus rhamnosus fsmm15, six prebiotics, including two milk-derived prebiotics, galactooligosaccharides and lacto-n-biose i, and four plant-origin prebiotics, beet oligosaccharide syrup, difructose anhydride iii, fructooligosaccharides, and raffinose, were examined. the strain utilized the milk-derived prebiotics at similar levels to glucose but did not utilize the plant-origin ones in the same manner, reflecting their genet ... | 2016 | 26858929 |
| crystallization and x-ray crystallographic analysis of the adhesive spac pilin subunit in the spacba pilus of gut-adapted lactobacillus rhamnosus gg. | gram-positive lactobacillus rhamnosus gg, a gut-adapted commensalic (and probiotic) strain, is known to express sortase-assembled pili on its cell surface. these spacba-called pili consist of three different types of building blocks; the spaa backbone-pilin subunit and the spab and spac ancillary pilins. spac is a relatively large (~90kda) multi-domain fimbrial adhesin, and while it is located primarily at the spacba pilus tip, occasionally, it can also be detected throughout the length of pilus ... | 2016 | 26732247 |
| effects of dietary supplementation of lactobacillus rhamnosus or/and lactococcus lactis on the growth, gut microbiota and immune responses of red sea bream, pagrus major. | pagrus major fingerlings (3·29 ± 0·02 g) were fed with basal diet (control) supplemented with lactobacillus rhamnosus (lr), lactococcus lactis (ll), and l. rhamnosus + l. lactis (lr + ll) at 10(6) cell g(-1) feed for 56 days. feeding a mixture of lr and ll significantly increased feed utilization (fer and per), intestine lactic acid bacteria (lab) count, plasma total protein, alternative complement pathway (acp), peroxidase, and mucus secretion compared with the other groups (p < 0.05). serum ly ... | 2016 | 26766177 |
| the n-terminal gypsy motif is required for pilin-specific sortase srtc1 functionality in lactobacillus rhamnosus strain gg. | predominantly identified in pathogenic gram-positive bacteria, sortase-dependent pili are also found in commensal species, such as the probiotic-marketed strain lactobacillus rhamnosus strain gg. pili are typically associated with host colonization, immune signalling and biofilm formation. comparative analysis of the n-terminal domains of pilin-specific sortases from various piliated gram-positive bacteria identified a conserved motif, called gypsy, within the signal sequence. we investigated th ... | 2016 | 27070897 |
| preserving viability of lactobacillus rhamnosus gg in vitro and in vivo by a new encapsulation system. | probiotics have shown beneficial effects on health and prevention of diseases in humans. however, a concern for application of probiotics is the loss of viability during storage and gastrointestinal transit. the aim of this study was to develop an encapsulation system to preserve viability of probiotics when they are administrated orally and apply lactobacillus rhamnosus gg (lgg) as a probiotic model to evaluate the effectiveness of this approach using in vitro and in vivo experiments. lgg was e ... | 2016 | 27063422 |
| probiotic compared with standard milk for high-caries children: a cluster randomized trial. | the aim of this study was to compare milk supplemented with probiotic lactobacilli with standard milk for the increment of caries in preschool children after 10 mo of intervention. the study was a triple-blind, placebo-controlled randomized trial. participants were children aged 2 and 3 y (n = 261) attending 16 nursery schools in a metropolitan region in chile. nursery schools were randomly assigned to 2 parallel groups: children in the intervention group were given 150 ml of milk supplemented w ... | 2016 | 26747421 |
| the expression of heterologous mam-7 in lactobacillus rhamnosus reduces its intrinsic capacity to inhibit colonization of pathogen vibrio parahaemolyticus in vitro. | vibrio parahaemolyticus (v. parahaemolyticus) is a gram-negative, halophilic bacterium recognized as one of the most important foodborne pathogen. when ingested, v. parahaemolyticus causes a self-limiting illness (vibriosis), characterized mainly by watery diarrhoea. treatment is usually oral rehydration and/or antibiotics in complicated cases. since 1996, the pathogenic and pandemic v. parahaemolyticus o3:k6 serotype has spread worldwide, increasing the reported number of vibriosis cases. thus, ... | 2016 | 26739707 |
| lactobacillus rhamnosus endocarditis: an unusual culprit in a patient with barlow's disease. | 2016 | 28302452 | |
| probiotic lactobacilli modulate staphylococcus aureus-induced activation of conventional and unconventional t cells and nk cells. | lactobacilli are probiotic commensal bacteria and potent modulators of immunity. when present in the gut or supplemented as probiotics, they beneficially modulate ex vivo immune responsiveness. further, factors derived from several lactobacilli strains act immune regulatory in vitro. in contrast, staphylococcus aureus (s. aureus) is known to induce excessive t cell activation. in this study, we aimed to investigate s. aureus-induced activation of human mucosal-associated invariant t cells (mait ... | 2016 | 27462316 |
| the role of probiotics in prevention of oral diseases. | the dynamic development of knowledge in the field of probiotics was commenced at the beginning of the 20th century. since then, many ways of their possible usage in medicine have been established. in accordance with the who, probiotics are live microorganisms, which if applied in adequate amounts may benefit the host. among probiotics, fungi and bacteria are distinguished, and mechanisms of action of these organisms in the oral cavity and gut are parallel. application in dentistry, in prophylaxi ... | 2016 | 27594560 |
| oral lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 to reduce group b streptococcus colonization in pregnant women: a randomized controlled trial. | this study is to examine the effect of lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 taken orally before bedtime on group b streptococcus (gbs)-positive pregnant women with respect to becoming gbs negative. | 2016 | 27590374 |
| doses lactobacillus reuteri depend on adhesive ability to modulate the intestinal immune response and metabolism in mice challenged with lipopolysaccharide. | the objective of this study was to evaluate the modulatory effects of lactobacillus reuteri zj617 and zj615, which have high and low adhesive abilities, respectively, and lactobacillus rhamnosus gg (lgg) on immune responses and metabolism in mice stimulated with lipopolysaccharide (lps). six c57bl/6 mice per group were orally inoculated with zj617, zj615 or lgg for one week (1 × 10(8) cfu/mouse) and i.p. injected with lps (10 mg/kg) for 24 h. compared with the lps stimulation group, zj615, zj617 ... | 2016 | 27323686 |
| biofilms of vaginal lactobacillus reuteri crl 1324 and lactobacillus rhamnosus crl 1332: kinetics of formation and matrix characterization. | adhesion and biofilm formation are strain properties that reportedly contribute to the permanence of lactobacilli in the human vagina. the kinetics of biofilm formation and the chemical nature of the biofilm matrix formed by lactobacillus reuteri crl (centro de referencia para lactobacilos culture collection) 1324 and lactobacillus rhamnosus crl 1332, vaginal beneficial strains, were evaluated in this work. crystal violet-stained microplate assay and techniques of epifluorescence, electron and c ... | 2016 | 27146055 |
| dietary prebiotics and bioactive milk fractions improve nrem sleep, enhance rem sleep rebound and attenuate the stress-induced decrease in diurnal temperature and gut microbial alpha diversity. | severe, repeated or chronic stress produces negative health outcomes including disruptions of the sleep/wake cycle and gut microbial dysbiosis. diets rich in prebiotics and glycoproteins impact the gut microbiota and may increase gut microbial species that reduce the impact of stress. this experiment tested the hypothesis that consumption of dietary prebiotics, lactoferrin (lf) and milk fat globule membrane (mfgm) will reduce the negative physiological impacts of stress. male f344 rats, postnata ... | 2016 | 28119579 |
| extensively hydrolyzed casein formula containing lactobacillus rhamnosus gg reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial. | children with cow's milk allergy (cma) have an increased risk of other allergic manifestations (ams). | 2016 | 28043872 |
| lactobacillus rhamnosus ncdc17 ameliorates type-2 diabetes by improving gut function, oxidative stress and inflammation in high-fat-diet fed and streptozotocintreated rats. | restoration of dysbiosed gut microbiota through probiotic may have profound effect on type 2 diabetes. in the present study, rats were fed high fat diet (hfd) for 3 weeks and injected with low dose streptozotocin to induce type 2 diabetes. diabetic rats were then fed lactobacillus rhamnosus ncdc 17 and l. rhamnosus gg with hfd for six weeks. l. rhamnosus ncdc 17 improved oral glucose tolerance test, biochemical parameters (fasting blood glucose, plasma insulin, glycosylated haemoglobin, free fat ... | 2016 | 28008783 |
| extensively hydrolyzed casein formula alone or with l. rhamnosus gg reduces β-lactoglobulin sensitization in mice. | extensively hydrolyzed casein formula (ehcf) has been proposed for the prevention and is commonly used for the treatment of cow's milk allergy (cma). the addition of the probiotic lactobacillus rhamnosus gg (lgg) to ehcf may induce faster acquisition of tolerance to cow's milk. the mechanisms underlying this effect are largely unexplored. we investigated the effects of ehcf alone or in combination with lgg on β-lactoglobulin (blg) sensitization in mice. | 2016 | 27992668 |
| dentifrice containing extract of rosmarinus officinalis linn.: an antimicrobial evaluation. | this study aimed to evaluate the antimicrobial activity of a dentifrice containing an alcoholic extract of rosemary on oral bacteria, compared to a commercially available herbal dentifrice. standard strains of streptococcus mutans (atcc 25175), streptococcus oralis (atcc 9811) and lactobacillus rhamnosus (atcc 7469) were used, as well as different toothpastes based on rosemary (tr), on propolis (th), triclosan (positive control) (tpc) and non-fluoridated dentifrice (negative control) (tnc). bact ... | 2016 | 27982224 |
| probiotics [lgg-bb12 or rc14-gr1] versus placebo as prophylaxis for urinary tract infection in persons with spinal cord injury [prosciuttu]: a study protocol for a randomised controlled trial. | urinary tract infections [utis] are very common in people with spinal cord injury [sci]. utis are increasingly difficult and expensive to treat as the organisms that cause them become more antibiotic resistant. among the sci population, there is a high rate of multi-resistant organism [mro] colonisation. non-antibiotic prevention strategies are needed to prevent uti without increasing resistance. probiotics have been reported to be beneficial in preventing utis in post-menopausal women in severa ... | 2016 | 27084704 |
| effect of probiotics on vaginal health in pregnancy. effpro, a randomized controlled trial. | preterm delivery is a leading cause of neonatal morbidity and death. it often results from chorioamnionitis, which is a complication of bacterial vaginosis. probiotics are effective in the treatment of bacterial vaginosis in women who were not pregnant; studies in pregnant woman are missing. | 2016 | 27342046 |
| isolated exopolysaccharides from lactobacillus rhamnosus gg alleviated adipogenesis mediated by tlr2 in mice. | the fibroblast cell line of 3t3-l1 was used as a cell model for screening and evaluating the feasibility of probiotic components in improving animal lipid metabolisms. the extracts from 12 lactobacillus strains caused significantly reduced triacylglycerol (tag) accumulation but with severe inflammation induction in 3t3-l1 adipocytes. interestingly, exopolysaccharides (eps) from lgg (lactobacillus rhamnosus gg) significantly decreased the tag accumulation without any inflammation. the anti-obesit ... | 2016 | 27786292 |
| lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model. | probiotics have been suggested as prophylactic measure in colon carcinogenesis. this study aimed at determining the potential prophylactic activity of lactobacillus rhamnosus gg cgmcc 1.2134 (lgg) strain on colorectal carcinogenesis via measuring its effect on nuclear factor kappa b (nfκb) inflammatory pathway and apoptosis. | 2016 | 27447122 |
| immunomagnetic separation combined with colony immunoblotting for selective enrichment and detection of piliated lactobacillus rhamnosus strains. | piliated lactobacillus rhamnosus (plr) strains have attracted much attention owing to their excellent mucus adhering capacity and immunomodulatory effects. here, we aimed to develop a rapid, sensitive method for isolating plr strains in complex ecosystems using immunomagnetic separation (ims) with colony immunoblotting (cib). | 2016 | 27552164 |
| a randomised controlled demonstration trial of multifaceted nutritional intervention and or probiotics: the healthy mums and babies (humba) trial. | maternal obesity is associated with adverse pregnancy outcomes and has lifelong negative implications for offspring health. the institute of medicine recommends limited gestational weight gain (gwg) in obese women for optimal maternal and infant outcomes. however, there is a gap regarding an effective and sustainable intervention strategy to achieve this goal. the aim of the healthy mums and babies (humba) demonstration trial is to assess whether a multifaceted nutritional intervention and/or an ... | 2016 | 27884128 |
| high fat diet induced atherosclerosis is accompanied with low colonic bacterial diversity and altered abundances that correlates with plaque size, plasma a-fabp and cholesterol: a pilot study of high fat diet and its intervention with lactobacillus rhamnosus gg (lgg) or telmisartan in apoe(-/-) mice. | atherosclerosis appears to have multifactorial causes - microbial component like lipopolysaccharides (lps) and other pathogen associated molecular patterns may be plausible factors. the gut microbiota is an ample source of such stimulants, and its dependent metabolites and altered gut metagenome has been an established link to atherosclerosis. in this exploratory pilot study, we aimed to elucidate whether microbial intervention with probiotics l. rhamnosus gg (lgg) or pharmaceuticals telmisartan ... | 2016 | 27821063 |
| a randomized clinical trial on the effectiveness of a symbiotic product to decolonize patients harboring multidrug-resistant gram-negative bacilli. | we aimed to evaluate the effectiveness of a symbiotic product to decolonize the intestinal tract of patients harboring multidrug-resistant (mdr) gram-negative bacilli and to prevent nosocomial infections. | 2016 | 27812649 |
| complete genome sequence of lactobacillus rhamnosus strain lrb. | lactobacillus rhamnosus is a gram-positive facultative heterofermentative lactic acid bacterium. it is often isolated from the gastrointestinal tract, mouth, vagina, and fermented dairy products. we have isolated the l. rhamnosus strain lrb from a healthy baby tooth that had naturally fallen out. here, we report the annotated whole-genome sequence of lrb. | 2016 | 27811096 |
| lactobacillus rhamnosus gg treatment improves intestinal permeability and modulates inflammatory response and homeostasis of spleen and colon in experimental model of pseudomonas aeruginosa pneumonia. | recent clinical trials and in vivo models demonstrate probiotic administration can reduce occurrence and improve outcome of pneumonia and sepsis, both major clinical challenges worldwide. potential probiotic benefits include maintenance of gut epithelial barrier homeostasis and prevention of downstream organ dysfunction due to systemic inflammation. however, mechanism(s) of probiotic-mediated protection against pneumonia remain poorly understood. this study evaluated potential mechanistic target ... | 2016 | 27745813 |
| [lactobacillus rhamnosus sepsis in a preterm infant associated with probiotic integrator use: a case report.] | preterm infants are at high risk of neonatal sepsis. we report a case of a preterm infant under prophylaxis with lactobacillus rhamnosus for necrotizing enterocolitis; the child develops neonatal sepsis by lactobacillus rhamnosus. the infection is improved after probiotic withdrawal and had complete remission after 20 days of specific antibiotic therapy. | 2016 | 27727257 |
| [non-antibiotic strategies to prevent the recurrence of uncomplicated urinary tract infections in women]. | the aim of all medical treatment is "primum nihil nocere" ("first, do no harm").restoring the integrity of intestinal microbiota and optimising the immune response in recurrent infections, especially in the urinary tract, are treatment alternatives which are closer to this target than the usual focus on antibiotic prevention of recurrence.in the future, antibiotics will continue to be recommended for the prevention of urinary tract infections on a case-by-case basis. however, the problems of an ... | 2016 | 27138235 |
| impact of a novel synbiotic supplementation during gestation and lactation on immune responses in the swiss albino mice offspring. | prebiotics from various regularly consumed cereals and novel substrates are currently being utilised as functional foods. the aim of this study was to determine the effect of synbiotic, formulated with prebiotic extracted from natural resources like green gram (vigna radiata) along with probiotic lactobacillus rhamnosus gg (lgg) in modulating immune responses in the offspring when supplemented during gestation and lactation. | 2016 | 27696418 |
| novel production protocol for small-scale manufacture of probiotic fermented foods. | a novel dried bacterial consortium of lactobacillus rhamnosus yoba 2012 and streptococcus thermophilus c106 is cultured in 1 l of milk. this fresh starter can be used for the production of fermented milk and other fermented foods either at home or at small-scale in rural settings. for the fresh starter, 1 l of milk is pasteurized in a pan that fits into a larger pan containing water, placed on a source of heat. in this water bath, the milk is heated and incubated at 85 °c for 30 min. thereafter, ... | 2016 | 27684196 |
| potential nociceptive regulatory effect of probiotic lactobacillus rhamnosus pb01 (dsm 14870) on mechanical sensitivity in diet-induced obesity model. | treatments for obesity have been shown to reduce pain secondary to weight loss. intestinal microbiota, as an endogenous factor, influences obesity and pain sensitivity but the effect of oral probiotic supplementation on musculoskeletal pain perception has not been studied systematically. the present study examined the effect of a single daily oral dose (1 × 10(9) cfu) of probiotics (lactobacillus rhamnosus pb01, dsm14870) supplement on mechanical pain thresholds in behaving diet-induced obese (d ... | 2016 | 27647980 |
| supplementation with lactobacillus rhamnosus sp1 normalises skin expression of genes implicated in insulin signalling and improves adult acne. | systemic supplementation with probiotics is increasingly being explored as a potential treatment strategy for skin disorders. because both the gut-skin axis and dysregulation of insulin signalling have been implicated in the pathogenesis of adult acne, we designed the current study to evaluate the effect of supplementation with the probiotic strain lactobacillus rhamnosus sp1 (lsp1) on skin expression of genes involved in insulin signalling and acne improvement in adult subjects. a pilot, random ... | 2016 | 27596801 |
| presumed allergic proctocolitis resolves with probiotic monotherapy: a report of 4 cases. | background the prevalence of allergic diseases has been dramatically rising in the united states and other developed nations over recent decades. growing evidence suggests a partial role for the microbiome in the development of these allergic diseases. food protein-induced allergic proctocolitis (ap) (also referred to as cow's milk protein intolerance or allergy) is among the earliest and most common food allergic diseases of infancy, yet its pathophysiology is not well understood. the currently ... | 2016 | 27568925 |
| probiotics as an environment-friendly approach to enhance red sea bream, pagrus major growth, immune response and oxidative status. | a usual strategy in modern aquaculture to combat production bottlenecks associated with intensification is preventive health care through the use of consumer and environment-friendly alternatives including probiotics. the current study evaluates the influence of lactobacillus rhamnosus (lr), a lyophilized probiotic bacterium, on health status and performance of red sea bream (pagrus major). probiotics were incorporated in the diets at four different concentrations: 0 (control diet, lr0), 10(2) ( ... | 2016 | 27542618 |
| probiotic pre-administration reduces mortality in a mouse model of cecal ligation and puncture-induced sepsis. | a number of clinical trials have demonstrated that the use of probiotics has the potential to prevent nosocomial infections. however, the mechanism underlying probiotic-induced anti-infection and sepsis remains to be investigated. in the present study, 200 µl/day of lactobacillus rhamnosus gg (lgg) or normal saline (control) was orally administrated to 4-week-old c57bl6 mice 4 weeks prior to cecal ligation and puncture (clp). a number of mice were sacrificed 24 h after clp, and the remaining mic ... | 2016 | 27588102 |
| survival and bioactivities of selected probiotic lactobacilli in yogurt fermentation and cold storage: new insights for developing a bi-functional dairy food. | in previous work, we demonstrated that two probiotic strains, namely lactobacillus casei pra205 and lactobacillus rhamnosus pra331, produce fermented milks with potent angiotensin-converting enzyme (ace)-inhibitory and antioxidant activities. here, we tested these strains for the survivability and the release of antihypertensive and antioxidant peptides in yogurt fermentation and cold storage. for these purposes three yogurt batches were compared: one prepared using yogurt starters alone (lactob ... | 2016 | 27554146 |
| can the development and autolysis of lactic acid bacteria influence the cheese volatile fraction? the case of grana padano. | in this study, the relationship between the dynamics of the growth and lysis of lactic acid bacteria in grana padano cheese and the formation of the volatile flavor compounds during cheese ripening was investigated. the microbial dynamics of grana padano cheeses that were produced in two different dairies were followed during ripening. the total and cultivable lactic microflora, community composition as determined by length heterogeneity-pcr (lh-pcr), and extent of bacterial lysis using an intra ... | 2016 | 27299670 |
| theoretical insight into the heat shock response (hsr) regulation in lactobacillus casei and l. rhamnosus. | the understanding of the heat shock response (hsr) in lactobacilli from a regulatory point of view is still limited, though an increased knowledge on the regulation of this central stress response can lead to improvements in the exploitation of these health promoting microorganisms. therefore the aim of this in silico study, that is the first to be carried out for members of the lactobacillus genus, was predicting how hsr influences cell functions in the food associated and probiotic species lac ... | 2016 | 27142777 |
| lactobacillus casei subsp. rhamnosus septicaemia in three patients of the paediatric intensive care unit. | 2016 | 28029469 | |
| probiotics in critically ill children. | gut microflora contribute greatly to immune and nutritive functions and act as a physical barrier against pathogenic organisms across the gut mucosa. critical illness disrupts the balance between host and gut microflora, facilitating colonization, overgrowth, and translocation of pathogens and microbial products across intestinal mucosal barrier and causing systemic inflammatory response syndrome and sepsis. commonly used probiotics, which have been developed from organisms that form gut microbi ... | 2016 | 27081478 |
| the spxb gene as a target to identify lactobacillus casei group species in cheese. | this study focused on the spxb gene, which encodes for pyruvate oxidase. the presence of spxb in the genome and its transcription could be a way to produce energy and allow bacterial growth during carbohydrate starvation. in addition, the activity of pyruvate oxidase, which produces hydrogen peroxide, could be a mechanism for interspecies competition. because this gene seems to provide advantages for the encoding species for adaptation in complex ecosystems, we studied spxb in a large set of che ... | 2016 | 27375244 |
| improvement in glucose tolerance and insulin sensitivity by probiotic strains of indian gut origin in high-fat diet-fed c57bl/6j mice. | diabetes and obesity are characterized by glucose intolerance, fat deposition, inflammation, and dyslipidemia. recent reports postulated that distinct gut microbiota alterations were observed in obese/diabetic subjects and modulating gut microbiota beneficially through specific probiotics could be a potential therapeutic option for type 2 diabetes/obesity. therefore, we attempted to study the efficacy of probiotics of indian gut origin (lactobacillus plantarum mtcc5690 and lactobacillus fermentu ... | 2016 | 27757592 |
| lactobacillus and leuconostoc volatilomes in cheese conditions. | new strains are desirable to diversify flavour of fermented dairy products. the objective of this study was to evaluate the potential of leuconostoc spp. and lactobacillus spp. in the production of aroma compounds by metabolic fingerprints of volatiles. eighteen strains, including five lactobacillus species (lactobacillus fermentum, lactobacillus helveticus, lactobacillus paracasei, lactobacillus rhamnosus, lactobacillus sakei) and three leuconostoc species (leuconostoc citreum, leuconostoc lact ... | 2016 | 26685674 |
| assessment and comparison of probiotic potential of four lactobacillus species isolated from feces samples of iranian infants. | the probiotic potential of lactobacillus species isolated from infant feces was investigated. for this study, the antibiotic susceptibility, tolerance in gut-related conditions, antimicrobial activity, and ability to adhere to a human colorectal adenocarcinoma cell line (caco-2 cells) of four common lactobacillus species (lactobacillus paracasei [n = 15], lactobacillus rhamnosus [n = 45], lactobacillus gasseri [n = 20] and lactobacillus fermentum [n = 18]) were assessed. most isolates that which ... | 2016 | 26648174 |
| development of antioxidant rich fruit supplemented probiotic yogurts using free and microencapsulated lactobacillus rhamnosus culture. | the present study reports the preparation of probiotic yogurt using lactobacillus rhamnosus. the standard starter cultures used for yogurt fermentation were streptococcus thermophilus and lactobacillus delbrueckii subsp. bulgaricus and obtained from ndri, karnal, india. the prepared yogurt was supplemented with fruit pulp (10 % w/v) of apricot, raspberries, plum and jamun. these fruits were rich in antioxidant property as observed by dpph, nitric oxide radical scavenging and ferric reducing anti ... | 2016 | 26787986 |
| development of a simple, low-cost and eurytopic medium based on pleurotus eryngii for lactic acid bacteria. | lactic acid bacteria (lab) are a group of important beneficial microorganisms for human, but their growth is restricted to the habitats with rich nutrients. in order to develop a simple, low-cost and efficient medium based on the mushroom pleurotus eryngii, this study evaluated the effects of different treatment methods for the mushroom, concentration of the mushroom, buffers, tween 80, mgso4·7h2o, mnso4·4h2o, cuso4·5h2o, riboflavin and ascorbic acid on the growth of lactococcus lactis subsp. la ... | 2016 | 27590888 |
| effect of inhibition on tyrosinase and melanogenesis of agastache rugosa kuntze by lactic acid bacteria fermentation. | this work presents the first report that a. rugosa could have tyrosinase and melanogenesis inhibition and that its activities also be improved by fermentation with lactobacillus rhamnosus and lactobacillus paracasei. it was found that the tyrosinase and melanogenesis inhibition was correlated with antioxidant activity of acacetin, the major biologically active substances in a. rugosa. | 2016 | 27531590 |
| impact of probiotic synbio(®) administered by vaginal suppositories in promoting vaginal health of apparently healthy women. | the purpose of this study was to investigate whether vaginal administration of probiotic lactobacillus results in their colonization and persistence in the vagina and whether it promotes normalization and maintenance of ph and nugent score. a single-arm, open-label controlled towards the baseline (pre-post) study including 35 apparently healthy women was conducted. each woman was examined three times during the study. women were instructed to receive daily for 7 days, the probiotic suppositories ... | 2016 | 27324341 |
| novel method based on chromogenic media for discrimination and selective enumeration of lactic acid bacteria in fermented milk products. | microbial analyses of fermented milk products require selective methods to discriminate between close species simultaneously present in high amounts. a culture-based method combining novel chromogenic agar media and appropriate incubation conditions was developed to enumerate lactic acid bacteria (lab) strains in fermented milk. m1 agar, containing two chromogenic substrates, allowed selective enumeration of lactobacillus rhamnosus, two strains of lactobacillus paracasei subsp. paracasei and str ... | 2016 | 26742619 |
| effects of fermentation with lactobacillus rhamnosus gg on product quality and fatty acids of goat milk yogurt. | the effect of fermentation with lactobacillus rhamnosus gg on the product quality of goat milk yogurt using traditional yogurt starter was studied through single-factor experiments and orthogonal experiments. the optimum fermentation condition was evaluated by the titratable acidity of goat milk yogurt, water-retaining capability, sensory score, and texture properties; the fatty acids of the fermented goat milk were determined by a gas chromatograph. results indicate that high product quality of ... | 2016 | 26601583 |
| lactobacilli differentially modulate mtor and wnt/ β-catenin pathways in different cancer cell lines. | lactobacilli are a group of beneficial bacteria whose anti cancer effects have been evaluated in different cancer cell lines as well as animal models and human subjects. such anti cancer effects can be exerted via different mechanisms such as modulation of immune response as well as inhibition of pathogens colonization. in addition, lactobacilli have direct cytotoxic effects against cancer cells which may be exerted through modulation of expression cancer related pathways. | 2016 | 27703648 |
| in vitro adherence of lactobacillus strains isolated from the vaginas of healthy iranian women. | the lactobacilli are a part of the bacterial flora of the human vagina. detection of normal lactobacillus species in the vaginas of healthy women in different geographical locations, and evaluation of their specific properties, can aid in the selection of the best species for preventing sexually transmitted diseases in the future. this study was performed to isolate and identify the lactobacillus species in the vaginas of healthy women and to evaluate the adherence of these lactobacilli to vero ... | 2016 | 27562422 |
| immunobiotic lactobacillus strains reduce small intestinal injury induced by intraepithelial lymphocytes after toll-like receptor 3 activation. | intestinal intraepithelial lymphocytes (iels) play critical roles in disrupting epithelial homeostasis after toll-like receptor (tlr)-3 activation with genomic rotavirus dsrna or the synthetic dsrna analog poly(i:c). the capacity of immunobiotic lactobacillus rhamnosus crl1505 (lr1505) or lactobacillus plantarum crl1506 (lp1506) to beneficially modulate iels response after tlr3 activation was investigated in vivo using a mice model. | 2016 | 27279272 |
| active lactobacillus rhamnosus la68 or lactobacillus plantarum wcfs1 administration positively influences liver fatty acid composition in mice on a hfd regime. | western life style, and high calorie diet in particular is causing major health problems such as insulin resistance, hepatic steatosis and heart disease in the modern age. high fat diet (hfd) induces similar changes in mice, such as increased body weight, hypercholesterolemia and accumulation of triglycerides in the liver. these changes can be ameliorated by the administration of some lactobacillus species. the focus of this study was to analyze the fatty acid content of liver, heart and brain t ... | 2016 | 27231730 |
| effectiveness of lactobacillus helveticus and lactobacillus rhamnosus for the management of antibiotic-associated diarrhoea in healthy adults: a randomised, double-blind, placebo-controlled trial. | broad-spectrum antibiotic use can disrupt the gastrointestinal microbiota resulting in diarrhoea. probiotics may be beneficial in managing this type of diarrhoea. the aim of this 10-week randomised, double-blind, placebo-controlled, parallel study was to investigate the effect of lactobacillus helveticus r0052 and lactobacillus rhamnosus r0011 supplementation on antibiotic-associated diarrhoea in healthy adults. subjects were randomised to receive 1 week of amoxicillin-clavulanic acid (875 mg/12 ... | 2016 | 27169634 |
| calcium phosphate supplementation increases faecal lactobacillus spp. in a randomised trial of young adults. | the aim of the studies was to determine the effects of calcium carbonate and calcium phosphate supplementation on faecal lactobacillus spp., with and without a probiotic supplement, in healthy adults. study 1 comprised of a randomised, double-blind, crossover design; participants (n=15) received 2 capsules/d of 250 mg elemental calcium as calcium carbonate (ca1) and calcium phosphate (ca2) each for 2-week periods, with 2-week baseline and washout periods. study 2 was a randomised, double-blind, ... | 2016 | 26503737 |