Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| cervical cancer cell lines containing herpesvirus markers. | five epithelioid cell lines were established from invasive cervical carcinoma tissue and were examined for herpes simplex virus (hsv) antigens or virus-induced changes. immunofluorescence studies with antiserum to an hsv type 2 nonstructural polypeptide detected perinuclear antigens. in these cell lines, concentrations of a membrane fucopeptide that is regularly present in normal cells were reduced to levels similar to those previously observed in virus-transformed cells. one of the cell lines i ... | 1979 | 231583 |
| tumorgenicity of herpesvirus hominis type 2-transformed cells (line 333-8-9) in adult hamsters. | inoculation of adult hamsters with greater than 1.5 x 10(2) herpesvirus type 2 (hsv-2) transformed hamster embryo fibroblasts induced rapidly growing tumours at the site of inoculation, in more than 50 per cent of animals. the tumours were examined by light and electron microscopy, and were histologically anaplastic fibrosarcomas. lung metastases were frequently found in tumour-bearing animals; these were usually only seen microscopically, and were cytologically similar to the primary tumours. t ... | 1979 | 231649 |
| [herpesvirus infection in kids in switzerland]. | 1979 | 231824 | |
| [herpesvirus hepatitis in cranes (aves:gruidae). i. pathomorphological findings]. | 1979 | 231876 | |
| an outbreak of foal perinatal mortality due to equid herpesvirus type 1: pathological observations. | twenty-nine cases of ehv1 infection occurred on a property, mainly in full term foals. some foals were stillborn, some were born alive but weak and soon died and others were healthy at birth, became ill and died within 3 days of birth. apart from voluminous, oedematous and atelectic lungs there were no gross lesions. microscopically the lungs showed oedema, pneumonitis and bronchiolitis with intranuclear inclusions and, in many of the foals that survived over 6 hours, there was also hyaline memb ... | 1979 | 232044 |
| inhibition of herpes simplex virus-induced dna polymerase activity and viral dna replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate. | the effect of the nucleoside analog 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine) on herpes simplex virus type 1 dna synthesis was examined. acycloguanosine inhibited herpesvirus dna synthesis in virus-infected cells. the synthesis of host cell dna was only partially inhibited in actively growing cells at acycloguanosine concentrations several hundred-fold greater than the 50% effective dose for herpes simplex virus type 1. studies using partially purified enzymes revealed that the triphosp ... | 1979 | 232189 |
| [isolation of the bovine herpesvirus-3 from sick calves]. | three herpes strains identified as herpes virus-3 were isolated in revolving test-tubes with cell cultures of nasal samples and lung parenchyma from diseased calves at the time of a respiratory enzooty. large crystalloid aggregates of herpes virus virions were observed in the nucleus and in the cytoplasma by the electron-microscopic investigation performed on infected cell cultures. the experimental infection of calves with the isolated strain produced slight symptoms of respiratory disease in s ... | 1979 | 232333 |
| equine herpesvirus type 3 (equine coital exanthema) in new south wales. | 1979 | 232418 | |
| pathogenesis of bovine herpesvirus-1 (bhv-1) infections: interactions of the virus with peripheral bovine blood cellular components. | 1979 | 232868 | |
| demonstration of cells with marek's disease tumor-associated surface antigen in chicks infected with herpesvirus of turkey, o1 strain. | the presence of marek's disease tumor-associated surface antigen (matsa) was demonstrated by the direct and indirect membrane immunofluorescent tests, in chicks inoculated 7-10 days earlier with herpesvirus of turkeys (hvt), o1 strain. in in vitro cultures of spleen lymphocytes and ovaries obtained from these chicks, matsa-positive cells were also detected after 1-7 days cultivation. a possible mechanism of protection by hvt vaccine against marek's disease is proposed. | 1979 | 233228 |
| skin ulceration associated with herpesvirus infection in cats. | three cases of skin ulceration in cats are described. herpesvirus was isolated from the ulcers. treatment of one case with antibiotics and an antiviral agent was successful. the significance of the viral isolate is discussed. | 1979 | 233275 |
| a study of bovid herpesvirus 2 infection in calves inoculated intradermally or intranasally. | bovid herpesvirus 2 infection was studied in calves exposed to the virus by intradermal inoculation of the skin of the left cheek or by nasal spray. in either case a localised infection developed and virus replication was shown to occur mostly in the tissues of its primary localisation, i.e. the skin of the left cheek or the nasal mucosa. there were neither secondary lesions, except at the site of virus injection, nor any serious systemic involvement on the part of the animals. the virus was als ... | 1979 | 233779 |
| enhanced plating efficiency of herpesvirus dna on herpes simplex virus type 1 dna-transformed cells. | partial resistance of hamster cells transformed by sheared herpes simplex virus (hsv) dna to superinfection by intact hsv could be overcome by transfection with viral dna's. hsv dna plated more efficiently on hsv type 1 dna-transformed hamster cells than on spontaneously transformed hamster or rabbit cells or on hamster cells transformed by other dna viruses. | 1979 | 214606 |
| case report: an outbreak of herpesvirus myeloencephalitis in vaccinated horses. | in the foaling season of 1977, five vaccinated horses in a standardbred breeding stable were affected with herpesvirus myeloencephalitis. respiratory and abortigenic forms also occurred in other individuals on the premises. equine herpesvirus type 1 was isolated from the brain of one case of myeloencephalitis and from lungs of two aborted fetuses. twelve of 16 horses demonstrated fourfold or greater increases in titres to equine herpesvirus type 1. | 1979 | 216473 |
| antibody responses to herpesvirus papio antigens in baboons with lymphoma. | an epstein-barr virus-related herpesvirus, termed herpesvirus papio (hvp), was isolated from baboons (papio hamadryas) at the institute of experimental pathology and therapy, sukhumi, ussr, where there is a continuing outbreak of lymphoma. in the present study sera from diseased baboons and from age- and sex-matched control animals were examined for antibodies to hvp antigens. results showed that animals with lymphoid disease had antibodies to hvp virus capsid, early, soluble, and nuclear antige ... | 1979 | 216640 |
| enhanced oncornavirus expression in marek's disease tumors from specific-pathogen-free chickens. | an oncornavirus was recovered from cell cultures of kidney tumors from specific-pathogen-free chickens inoculated with marek's disease herpesvirus (mdhv). the mdhv inoculum was free of infectious avian leukosis virus (alv). direct examination of a variety of tissues from mdhv-inoculated chickens demonstrated increased levels of alv-specific rna compared to tissues from diluent-inoculated (control) chickens. dna from cultured kidney tumor cells annealed to an alv complementary dna probe at the sa ... | 1979 | 216833 |
| varicella-zoster virus immunizes patas monkeys against simian varicella-like disease. | to define further the antigenic relationship between human varicella-zoster virus and herpesviruses which produce varicella-like disease in certain simian species, patas monkeys were inoculated with varicella-zoster virus and then challenged with delta herpesvirus, which uniformly produces severe, clinically apparent disease in susceptible animals. protection against delta herpesvirus was conferred both by hyperimmunization with varicella-zoster virus and by a single immunization with a cell-fre ... | 1979 | 215708 |
| characterization of an epstein-barr virus-induced dna polymerase. | the addition of iododeoxyuridine to p3hr-i cell cultures led to a large increase in both epstein-barr virus (ebv)-induced dna polymerase activity and early antigen-positive cells. this ebv-induced dna polymerase was separated from the cellular alpha- and beta-polymerases by sequential column chromatography on sepharose 6b, deae-cellulose, and phosphocellulose, resulting in partial purification of about 320-fold. the partially purified-ebv dna polymerase could be distinguished from the cellular d ... | 1979 | 219209 |
| persistence of herpes simplex virus type 1 in rat neurotumor cells. | herpes simplex virus type 1 (hsv-1) infection of a rat central nervous system tumor cell line led to almost complete destruction of the cells. cells that survived the infection could be isolated and shown to produce infectious hsv particles for variable lengths of time in culture ranging from 20 to 57 passages. even though infectious virus production eventually ceased, the cell lines continued to produce herpes-specified proteins as measured by immunological techniques. these cells also showed h ... | 1979 | 219234 |
| no homology detectable between marek's disease virus (mdv) dna and herpesvirus of the turkey (hvt) dna. | the relation of four different strains of mdv and two strains of hvt was analyzed by gel electrophoresis of viral dna digested by various restriction endonucleases and by filter hybridization of viral dna with complementary rna. the four mdv strains showed fragment patterns completely different from those of hvt upon digestion of the viral dna with bam h i, eco r i, hind iii, hpa, i, and xho and separation of fragments on agarose gels. the cleavage patterns of the four mdv strains showed great s ... | 1979 | 219323 |
| respiratory viruses in hospital patients on the witwatersrand. a 7-year study. | virological investigations were carried out on 4 151 patients with respiratory disease hospitalized between may 1966 and april 1972. the groups examined were black and white children and black miners. influenza viruses were more common among malnourished black children and tended to cause more severe disease. this was also true of adenovirus and herpesvirus hominis type 1 infections. adenoviruses appear to be secondary invaders, frequently after a measles or influenza attack. a generalized epide ... | 1979 | 219551 |
| purification and characterization of deoxythymidine kinase (dtk) induced in dtk- 3t3 mouse cells by equine herpesvirus type 1 (ehv-1). | 1979 | 218350 | |
| biological and biochemical properties of defective interfering particles of equine herpesvirus type 1. | 1979 | 218357 | |
| extreme sensitivity of enveloped viruses, including herpes simplex, to long-chain unsaturated monoglycerides and alcohols. | unsaturated monoglycerides and alcohols of chain lengths of 16 or 18 carbons were found to be extremely potent inactivators of two enveloped viruses, herpes simplex virus type 2 and bacteriophage phi6. the lipid-containing bacteriophage pm2 was also inactivated by some of these amphiphilic molecules. treatment of herpes simplex virus type 2 with these compounds at concentrations as low as 0.2 mum reduced virus survival to 50% in 30 min, making these agents the most potent inactivators of herpes ... | 1979 | 218499 |
| further study on the three-dimensional structure of the core of marek's disease virus and herpesvirus of turkey. | three-dimensional structures of the core of marek's disease virus and herpesvirus of turkey were examined by the tilting apparatus of an electron microscope. various types of the core found in the infected cells were considered to represent developmental stages of the viruses. the basic structure of the core consisted of a toroid surrounding a cylindrical mass, which was clearly demonstrated by tilting the core in two directions. a cylindrical mass spooled by more than two toroids, which seemed ... | 1979 | 218531 |
| herpesvirus hominis antibodies among children and young adults in ibadan. | a total of 422 sera collected from children and young adults living in ibadan, nigeria, has been examined for the presence of antibodies to type 1 and type 2 herpesvirus hominis. type 1 antibodies were rapidly acquired from the age of 1 year onwards, reflecting the relatively poor living standards and the overcrowded accommodation among the population studied. type 2 antibodies were acquired between the ages of 3 and 5 years. it is suggested that non-venereal spread of the virus must be responsi ... | 1979 | 218671 |
| epidemiology of equine upper respiratory tract disease on standardbred racetracks. | the outbreaks of upper respiratory tract infections in horses at standardbred racetracks were investigated over a three year period. the most serious epidemics of respiratory disease occurred in the winter and spring seasons. both influenza viruses and equine herpesvirus 1 were shown to be present in the horse population. the herpesvirus was associated with respiratory disease particularly in the winter but the equine influenza viruses apparently were responsible for the major epidemics of respi ... | 1979 | 218705 |
| a comparative study of bovine herpesvirus 1247 and equine herpesvirus 1 in ponies. | the clinical and immunological response of ponies exposed to a bovine herpesvirus isolate and equine herpesvirus 1 were compared. each virus was inoculated into two ponies by the intranasal route. one uninoculated pony was used with each group as a contact control. the four inoculated ponies developed a mild rhinitis with an increase in rectal temperature. virus was recovered from nasal secretions collected from the four inoculated and one contact pony. all ponies developed a serum neutralizing ... | 1979 | 218710 |
| interaction in replication between goose parvovirus strain b and duck plague herpesvirus. | the goose parvovirus strain b was found to replicate only in cells with dna synthesis. cells in the stationary phase of dna synthesis or maintained under 2 mm thymidine (tdr) in excess were refractive to the parvovirus infection. however, stationary phase cells could be rendered to produce progeny paroviruses by herpesvirus superinfection. in reverse, the replication of the herpesvirus was significantly inhibited by parvovirus preinfection of cells. | 1979 | 426633 |
| herpesvirus infection of the esophagus and other visceral organs in adults. incidence and clinical significance. | 1979 | 433952 | |
| [primary disseminated herpesvirus hominis type 2 infection in a healthy adult]. | a healthy 26-year-old patient presented a primary herpetic type 2 infection. the infection disseminated to the skin, the mucosa and the liver. the clinical course of the infection had a favorable issue. | 1979 | 437228 |
| systemic herpesvirus hominis in pregnancy. | primary genital herpesvirus infection occurring in late gestation may provide the portal of entry for systemic infection. this report describes the clinical events and pathologic findings of lethal disseminated herpetic infection after a primary genital lesion in late gestation and reviews the physiologic changes of pregnancy that may cause the failure of normal defenses against the systemic spread of the virus. | 1979 | 439094 |
| [vaccination of field and experimental flocks with lyophilized turkey herpesvirus: antibody response of vaccinated chickens (author's transl)]. | 1979 | 439540 | |
| relation of hvh-ii to carcinoma of the cervix. | an animal model is described that demonstrates the development of varying degrees of basal cell hyperplasia, metaplasia, and dysplasia following cervicovaginal herpesvirus hominis type ii (hvh-ii) infection. although the study spanned a period of 30 months, the equivalent of 60 human years, there was no evidence of anaplasia. these results are considered in relation to the role of hvh-ii as an initiator in the multistep process leading to cervical carcinoma. | 1979 | 440666 |
| a new method for producing virus plaques in cell cultures. | human oesophageal carcinoma cells can be grown on one side of a microporous gelatin membrane and fed from the other side. when they are infected with human herpesvirus type i at high dilutions, they produce plaques of virus-infected cells which can be detected by ordinary staining methods. this procedure may be suitable for the determination of the numbers of infectious particles in preparations of other viruses which are difficult to assay by conventional plaque assay techniques. | 1979 | 441897 |
| enhancement of herpesvirus type 2 infection in pregnant mice. | 1979 | 450905 | |
| the serological relationship of herpesvirus ovis to other herpesviruses and its possible involvement in the aetiology of jaagsiekte. | cross-neutralization studies showed that 3 different isolates of herpesvirus ovis from cell cultures derived from the lungs of sheep suffering from jaagsiekte were not only identical but were also related to similar isolate made in scotland. no relationship, however, could be established between herpesvirus ovis and common bovine or equine herpesviruses. antibodies to herpesvirus ovis were present in roughly 70% of all animals tested and no evidence was obtained for the involvement of the virus ... | 1979 | 460824 |
| characteristics of herpesvirus mutants resistant to phosphonoformate and phosphonoacetate. | mutants of herpes simplex virus type 1, resistant to phosphonoformate (pfa) and phosphonoacetate (paa), have been selected in cell culture. the pfa-resistant mutant (hsv-pfa(r)) and the paa-resistant mutant (hsv-paa(r)) were also resistant to paa and pfa, respectively. this cross-resistance indicates that pfa and paa interact at the same site. the hsv-pfa(r) had a decreased susceptibility to vidarabine, but no difference in sensitivity to idoxuridine (5-iodo-2'-deoxyuridine) was observed when co ... | 1979 | 475360 |
| characterization of paramyxo-, herpes-, and orbiviruses isolated from psittacine birds. | isolates of paramyxo-, herpes-, and orbiviruses from psittacine birds were characterized in the course of studies in cell cultures. the lbd-1 isolate, from a lovebird, was grown in chick kidney (ck) cells. it had the properties of a paramyxovirus but was found tobe serologically distinct from known avian paramyxoviruses. this virus was pathogenic for japanese quail but not for young chickens or budgerigars. rsl-1 and -2, isolated from diseased rosellas, were propagated in chicken embryo fibrobla ... | 1979 | 486000 |
| effects of vaccination for marek's disease on growth of a marek's-virus-induced transplantable lymphoma in syngeneic and allogeneic chickens. | a study was made of the effects of vaccination with turkey herpesvirus on the growth of tumors following inoculation of lymphoma cells induced by marek's disease virus (mdv). the cells used were from a transplantable mdv-induced lymphoid tumor (mdt-198) maintained by passaging in syngeneic hosts. vaccination did not prevent progressive tumor growth or alter subsequent mortality among syngeneic recipients of mdt-198 cells. with allogeneic recipients, however, vaccination had a significant protect ... | 1979 | 486007 |
| experimental bovine pneumonic pasteurellosis. i. prevention of the disease. | fifteen three- to six-month old hereford-cross calves were divided into three groups. the first group was inoculated with bovid herpersvirus 1 (strain 108), the second with a commercial intranasal vaccine against bovid herpesvirus 1 and the third group acted as controls. at least three weeks after vaccination, all calves were weaned, placed in an environmental chamber at 25.0 degrees c (days) and -13.3 degrees c (nights) and challenged with an aerosol of bovid herpesvirus 1 followed four days la ... | 1979 | 487247 |
| experimental bovine pneumonic pasteurellosis. ii. genesis and prevention. | two experiments were conducted. in the first, 16 crossbred hereford calves were divided into two equal groups. the first group was vaccinated intranasally with a commercial vaccine against bovid herpesvirus 1 and the second group was unvaccinated. the calves were later exposed to an aerosol of bovid herpesvirus 1 (strain 108) for five minutes. four calves from each group were subjected to transportation and four calves from each group were kept in an environmental chamber for four days. four day ... | 1979 | 487248 |
| purification and biochemical characterization of deoxythymidine kinase of deoxythymidine kinase-deficient mouse 3t3 cells biochemically transformed by equine herpesvirus type 1. | a line of mouse 3t3 cells lacking deoxythymidine kinase (dtk-) was stably transformed to see dtk+ phenotype after exposure to ultraviolet-irradiated equine herpesvirus type 1 (ehv-1). deoxythymidine kinase (dtk) was purified from the biochemically transformed mouse cells by affinity chromatography on deoxythymidine-sepharose. the purified dtk from ehv-1-transformed 3t3 cells was identical to the dtk purified from dtk- 3t3 cells lytically infected with ehv-1 with respect to its electrophoretic mo ... | 1979 | 489123 |
| the virus neutralizing activity of antibodies specific to the envelope and nucleocapsid of equine herpesvirus type 1. | antibodies specific to the envelope or nucleocapsid of the kentucky-d strain of equine herpesvirus type 1 were isolated from convalescent horse serum by immunoadsorption on cyanogen bromide-activated sepharose conjugated with equine herpesvirus type 1 envelopes or nucleocapsids, with subsequent elution by glycine buffer. in double immunodiffusion and immunolectrophoresis reactions, the eluted proteins appeared to belong to the igg fraction of horse serum. antibodies directed against the viral en ... | 1979 | 497891 |
| arabinosylthymine: inhibitor of splenic lymphocyte macromolecular synthesis in vitro. | the effect of arabinosylthymine on lymphocyte transformation was investigated. arabinosylthymine was demonstrated not to be cytotoxic for hamster spleen lymphocytes but was found to inhibit the increase in deoxyribonucleic acid and protein synthesis usually observed as a result of mitogen stimulation. these findings suggest that, in addition to being a potent anti-herpesvirus inhibitor, arabinosylthymine is also an immunosuppressive agent. | 1979 | 500206 |
| effect of trisodium phosphonoformate in genital infection of female guinea pigs with herpes simplex virus type 2. | a genital herpesvirus type 2 infection in guinea pigs has been used to evaluate the inhibitory effect of phosphonoformate on the infection. an early topical treatment prevented the appearance of vesicles and histopathological changes and no virus could be recovered. when treatment, either topical or both systemic and topical, was delayed to 24 hours post infection no therapeutic effect was observed. | 1979 | 508093 |
| [variations in resistance of viruses from different groups to chemico-physical decontamination methods]. | the resistance of a total of 13 different viruses to some important chemico-physical influences was studied under uniform experimental conditions. stability in tape water, thermostability and sensitivity to anodic oxidation, gamma radiation, some virucidal substances and several commercial disinfectants were tested. in evaluating the results, an attempt is made to rank the viruses investigated according to their sensitivity. on average a bovine parvovirus, and also a reovirus and three enterovir ... | 1979 | 511342 |
| purification of the js-3 isolate of herpesvirus ovis (bovid herpesvirus 4) and some properties of its dna. | a procedure incorporating the use of heparin was developed to purify herpesvirus ovis. the viral dna has a buoyant density of 1.706 +/- 0.001 g/cm3, and the sedimentation constant was estimated to be 47.5 +/- 1.5s; from the latter, the molecular weight was calculated as 67.3 +/- 5.4 x 10(6). estimates of the guanine-plus-cytosine content made from the buoyant density and melting point (72 degrees c) gave levels of 47 and 46%, respectively. | 1979 | 513200 |
| a model for herpesvirus (class 3) dna during infection, latency, and transformation. | 1979 | 523289 | |
| assay of interferon and viral antibodies in the cerebrospinal fluid in clinical neurology and psychiatry. | cerebrospinal fluids (csf) of 245 neurological and 194 psychiatric patients were tested for viral antibodies and interferon. complement dependent neutralizing antibodies to herpesvirus hominis 1 were found in the csf of patients with encephalitis (50.6%), meningitis (35.4%), lesions of peripheral nerves (36.9%), sclerosis multiplex (41.2%), schizophrenia (31.9%), senile dementia (51.4%), mental retardation (11.1%), ethylism (43.5%). neutralizing antibodies to tick-borne encephalitis virus were f ... | 1979 | 525159 |
| use of modified live bovine herpesvirus 1 vaccines. | 1979 | 532054 | |
| effects of interferon and adenine arabinoside treatment of hepatitis b virus infection on cellular immune responses. | fifteen patients with chronic hepatitis b were treated with adenine arabinoside (ara-a) or human leukocyte interferon (hli). cellular immune response to hepatitis b virus surface antigen and antigens prepared from herpes simplex virus, varicella zoster virus, and cytomegalovirus was measured by a lymphocyte blast transformation assay and an assay for interferon production. measurements were made before, during, and after antiviral treatment. unlike patients convalescing from acute hepatitis b, o ... | 1979 | 533259 |
| [detection of the canine herpesvirus in a case of whelp death]. | 1979 | 538448 | |
| studies on the temperature-dependent dna replication of the herpesvirus of the turkey in chicken embryo fibroblasts. | the development of cytopathogenic changes in chicken embryo fibroblasts infected with the herpesvirus of the turkey, strain pb-thvi, and the release of virus particles into the supernatant of infected cultures is accelerated at temperatures higher than 37 degrees c and is fastest at 41 degrees c, the normal body temperature of chickens. the growth rate of hvt in cef cultures was followed by determination of the number of virus genome equivalents within infected cells at various time intervals p. ... | 1979 | 541663 |
| pathogenicity of a marek's disease virus for chickens vaccinated with graded doses of herpesvirus of turkeys. | six different groups of one-day-old chickens were vaccinated with herpesvirus of turkeys (hvt) vaccine at doses of 0, 4, 16, 64, 256 and 1,024 plaqueforming units. at 9 days of age they were challenged with an acute strain of marek's disease herpesvirus (mdhv). gross and microscopic lesions in nerves and gonads were investigated and combined for quantitative expression of mdhv pathogenicity. including the microscopic lesions improved the accuracy of the hvt doses/mdhv response. the qualitative a ... | 1979 | 546406 |
| iontophoretic application of idoxuridine for recurrent herpes labialis: report of preliminary clinical trials. | in clinical trials on six patients the antiviral drug idoxuridine (stoxil) was applied by anodal (+) iontophoresis to 14 recurrent herpes labialis lesions. results were characterized by immediate relief of discomfort and swelling, rapid appearance and coalescence of vesicles, minimal or no spread of the lesions, and accelerated healing with minimal or no scab. these encouraging trials indicate that a full-scale, double-blind, controlled clinical study should be carried out to determine whether i ... | 1979 | 552584 |
| herpesvirus hominis (type 1) proctitis. | herpes proctitis from herpesvirus hominis type 1 is probably an underrecognized cause of rectal pain and inflammation. extreme anal pain and a purulent rectal discharge in a heterosexual man led to the appropriate diagnosis. clinicians should be more aware of herpes as a cause of proctitis. | 1979 | 553097 |
| successful treatment of human genital herpes infections with 2-deoxy-d-glucose. | thirty-six women with genital herpes infections (proved by virological or cytological means) were treated in a double-blind placebo-controlled study with the glucose analogue 2-deoxy-d-glucose for a three-week period. in initial mucocutaneous cases, 89% were cured, with two recurrences after 24 months; in the case of recurrent or secondary infections, 90% had a notable improvement manifested by no or less-frequent recurrences, fewer lesions, or shortened duration of symptoms. in initial infectio ... | 1979 | 221691 |
| route of herpesvirus spread traced with aid of dna-cleaving enzymes. | 1979 | 221697 | |
| lymphoid neoplasms in chicken flocks free of infection with exogenous avian tumor viruses. | more than 4,500 breeding female chickens of nine inbred lines maintained under specific-pathogen-free conditions to approximately 500 days of age were studied. routine monitoring and special assays indicated that they were free of infection by exogenous viruses of the leukosis-sarcoma and the reticuloendotheliosis groups. some birds were maintained free of marek's disease (md) virus infection in plastic isolators, and others were maintained in conventional chicken houses and vaccinated with the ... | 1979 | 221715 |
| prevention of reactivated herpes simplex infection by human leukocyte interferon after operation on the trigeminal root. | microneurosurgical procedures on the trigeminal-nerve root are often followed by reactivation of herpes simplex virus infection, manifested by herpes labialis or oropharyngeal herpesvirus shedding or both. in a double-blind study of the ability of human leukocyte interferon to prevent this reactivation, patients with a history of herpes labialis were given 7 x 10(4) u of interferon per kilogram of body weight per day or placebo for five days beginning on the day before operation. in 18 patients ... | 1979 | 221812 |
| detection of a nuclear antigen in herpesvirus ateles-carrying marmoset lines by the acid-fixed nuclear binding technique. | in vitro binding of a herpesvirus ateles (hva)-associated soluble antigen to amphibian erythrocyte nuclei was demonstrated by the acid-fixed nuclear binding technique in combination with anticomplement immunofluorescence. incubation of concentrated salt-extracted soluble antigens derived from hva-carrying marmoset lines with methanol/acetic acid-fixed erythrocytes of frogs and salamanders resulted in a brilliant nuclear fluorescence after exposure to a live virus-boostered, anti-hvs-positive squ ... | 1979 | 221913 |
| sensitivity and specificity of diagnostic tests for genital infection with herpesvirus hominis. | three smear techniques for diagnosis of herpesvirus hominis infection were evaluated by study of 168 unselected patients with genital lesions attending a venereal disease clinic. a tissue culture and results of three smear techniques were obtained for each patient in random order. h. hominis was recovered from 101 patients (60%). all three smear tests (immunofluorescence, papanicolaou, and crystal violet) were highly specific, but the sensitivity of each was smaller than or equal to 40% among pa ... | 1979 | 221993 |
| risk factors in lip cancer: a questionnaire survey. | an analysis was made of potential risk factors of cancer of the lip in finland. the series comprised 290 lip cancer patients, and the controls were 254 patients with squamous cell carcinoma of the skin of the head and neck, all reported to the finnish cancer registry in 1972-1973. the results obtained in a questionnaire survey (response rate, 75%; 54% of the total series) indicated that the male lip cancer patients had engaged in outdoor work and smoking with significantly greater frequency than ... | 1979 | 222137 |
| immune control of herpesvirus latency. | 1979 | 222416 | |
| bovine abortion associated with mixed movar 33/63 type herpesvirus and bovine viral diarrhea virus infection. | a herpesvirus and cytopathogenic bovine viral diarrhea virus were isolated from a bovine fetus aborted in the 6th month of gestation. the herpesvirus was serologically indistinguishable from bovine herpesviruses dn-599 and movar 33/63. | 1979 | 222535 |
| persistent infection of a human lymphoblastoid cell line with equine herpesvirus 1. | infection of a human lymphoblastoid cell line (jijoye line derived from a burkitt lymphoma which contains epstein-barr virus) with equine herpesvirus 1, maintained and observed for 53 days, was characterized by the continuous production of infectious extracellular and intracellular virus. maximum virus production correlated with active cell multiplication. less than 15% of the cells possessed viral capsid antigen at any one time. five percent of the cells in the jijoye line possess epstein-barr ... | 1979 | 222688 |
| pleocytosis and immunoglobulin changes in cerebrospinal fluid and herpesvirus serology in patients with guillain-barré syndrome. | in a follow-up study of 24 patients with guillain-barré syndrome, 55% developed a cerebrospinal fluid (csf) mononuclear pleocytosis, which persisted for 4 months or more. raised index values of csf-immunoglobulin g (igg), csf-iga, and csf-igm, indicating synthesis of the immunoglobulin in question in the central nervous system, were found in 63, 35, and 25%, respectively. agarose gel eletrophoresis revealed oligoclonal immunoglobulin in csf in 21% and in both csf and serum in another 21% of the ... | 1979 | 222797 |
| comparison of indirect hemagglutination and indirect immunofluorescence tests with microneutralization tests for detection of type-specific herpesvirus hominis antibody. | indirect hemagglutinating and immunofluorescent antibody responses to herpesvirus hominis types 1 and 2 were compared to neutralizing antibody responses in infected humans from whom h. hominis type 1 or 2 was isolated. the indirect immunofluorescent antibody test was shown to be the most sensitive and specific for primary human infections. the sensitivity and specificity of the indirect hemagglutination and the immunofluorescent antibody tests were shown to be equal to that of the microneutraliz ... | 1979 | 222800 |
| simultaneous radioimmunoassay for specific antibodies to members of the human herpesvirus group. | a method of described for the simultaneous radioimmunoassay (ria) for antibody to members of the human herpesvirus group. the ria is compared with some of the conventional serologic techniques used to quantitate antibody to these viruses (epstein-barr virus, cytomegalovirus, herpesvirus type 1 and varicella-zoster virus). color-coded beads, each coated with the antigens of a different herpesvirus, were similtaneously placed in a well which contained a human serum to be assayed for antibody to ea ... | 1979 | 222846 |
| isolation of a herpesvirus from an american kestrel with inclusion body disease. | a herpesvirus was isolated from the liver of a captive-bred american kestrel (falco sparverius) which had died of inclusion body disease. initial isolation was achieved in chicken embryo fibroblasts after three blind passages. cell-adapted virus produced a distinct rounding of cef cells within 24 to 48 h. biologic and serologic tests suggested that the kestrel virus is similar to falcon herpesvirus and pigeon herpesvirus and is at least partially related to owl herpesvirus. however, serologic te ... | 1979 | 222917 |
| expression of genetic resistance to an oncogenic herpesvirus at the target cell level. | 1979 | 223067 | |
| persistence of virus shedding in asymptomatic women after recovery from herpes genitalis. | one hundred seventeen women were reexamined within 6 months after presenting with genital herpes. swabs for virus isolation were taken from the cervix whether or not lesions were observed. herpesvirus type ii was isolated from 30 of 67 patients with recurrent disease, but also from 5 of 50 women during periods when there were no signs or symptoms of illness. the epidemiologic importance of virus shedding from asymptomatic women is discussed. | 1979 | 223095 |
| some aspects of the role of viruses in cancer. | the cells of tumours induced by many oncogenic dna viruses, or cells transformed in vitro, contain virus-specific t and transplantation antigens; these have been described for sv40 virus, polyoma virus and adenoviruses. the investigation of viruses as causes of malignant disease in man has sought to establish whether tumour cells possess these virus-specific proteins; however, to date and with the limitations of present techniques, this enquiry has not demonstrated the above viruses as causal of ... | 1979 | 223141 |
| sites of sequence variability in epstein-barr virus dna from different sources. | the intracellular epstein-barr virus (ebv) dna present in virus-transformed cells was partly purified from 23 cell lines or biopsies of burkitt lymphoma, nasopharyngeal carcinoma, infectious mononucleosis, or healthy carrier origin. such dna was cleaved in fragments (a-k) of molecular weights between 1 x 10(6) and 30 x 10(6) with restriction enzyme ecori, and these fragments were analyzed by standard methods involving agarose gel electrophoresis, transfer to nitrocellulose filters, and hybridiza ... | 1979 | 223159 |
| prior immunization by herpesvirus. | 1979 | 223444 | |
| differentiation of field strains and a vaccine strain of equine herpesvirus 1, using plaque characteristics. | 1979 | 223480 | |
| genital chlamydia trachomatis infections in patients with cervical atypia. | of 177 gynecologic outpatients with cervical dysplasia studied, 29 (16%) were found to excrete chlamydia trachomatis from their urogenital tract. sera collected from 93 of these patients were significantly more often positive for and showed higher levels of antichlamydial micro-complement fixation (cf) and immunofluorescence (if) antibodies than sera obtained from the controls. however, when the sera were tested for anti-herpesvirus type ii (hsv-ii) and cytomegalovirus (cmv) antibodies, no diffe ... | 1979 | 224353 |
| transcription of the genome of pseudorabies virus (a herpesvirus) is strictly controlled. | 1979 | 224585 | |
| infection studies on a reticuloendotheliosis virus contaminant of a commercial marek's disease vaccine. | reticuloendotheliosis virus (rev) was isolated in cell cultures from commercial marek's disease (herpesvirus of turkeys) vaccine and re-isolated from the organs of vaccinated chickens. runting and feathering abnormalities were produced when 1-day-old specific pathogen free chickens were inoculated with rev. histopathological lesions in infected chickens were hypoplasia of the thymus, bursa and spleen, and inflammation of the proventriculus, kidneys and liver. serological responses to rev were de ... | 1979 | 223539 |
| proteins of equine herpesvirus type 3. i. polypeptides of the purified virion. | 1979 | 217165 | |
| extraction of soluble antigens of epstein-barr virus, herpesvirus salmirl, and herpesvirus ateles with the use of glycine. | for extraction of soluble antigen from cells infected with epstein-barr virus, herpesvirus salmirl, and h. ateles, 0.1 m glycine (ph 9.5) was used. this method yielded increased amounts of the antigen containing much less cell debris. lymphoblastoid cells infected with epstein-barr virus could maintain up to 50% viability after the extraction procedure. these cells could be used again after an appropriate interval in culture. the usefulness of this technique is discussed. | 1979 | 220447 |
| isolation of a cytomegalovirus from salivary glands of white-lipped marmosets (saguinus fuscicollis). | minced salivary glands from seven white-lipped marmosets (saguinus fuscicollis and saguinus nigricollis) and one cotton-topped marmoset (saguinus oedipus) were cocultivated with marmoset cell cultures. a viral agent, designated ssg, was isolated from two saguinus fuscicollis. slowly progressing foci of rounded, vacuolated, refractile cells were first observed at 40-43 days incubation. electron microscopy revealed intranuclear herpesvirus nucleocapsids and intracytoplasmic and extracellular envel ... | 1979 | 220464 |
| experimental canine herpesvirus infection in newborn puppies, using a new zealand isolate. | 1979 | 220572 | |
| cesarean section and genital herpesvirus infection. | 1979 | 220577 | |
| replication of herpesvirus dna. iv: analysis of concatemers. | 1979 | 220789 | |
| adenovirus-associated virus polypeptides synthesized in cells coinfected with either adenovirus or herpesvirus. | 1979 | 219599 | |
| minor dna homology between herpesvirus of turkey and marek's disease virus? | 1979 | 219602 | |
| persistence of herpes simplex virus types 1 and 2 in infected individuals. | during a 23-month period, 18 patients with facial or genital herpetic lesions were examined; culture specimens from each patient were obtained three times per week for virologic studies. the isolated viruses were identified, and the average duration of herpesvirus in lesions was determined. herpes simplex virus type 1 (hsv-1) was isolated from facial lesions for a mean duration of 3 1/2 days. in contrast, herpes simplex virus type 2 (hsv-2) was isolated from genital lesions for a mean duration o ... | 1979 | 219784 |
| ascending infection following cervicovaginal exposure to herpesvirus hominis type ii. | an animal model is presented that demonstrates that following cervicovaginal inoculation, infective doses of herpesvirus hominis type ii induce a form of herpetic encephalitis. immunofluorescent results indicate that there is both neural and hematogenous spread of the herpes infection. the possible role of a latent viral infection in the genesis of an acute disease of the central nervous system is investigated in this experimental system. | 1979 | 375146 |
| clinical course and diagnosis of genital herpes simplex virus infection and evaluation of topical surfactant therapy. | a prospective study of 37 men and 32 women with culture-proved genital herpes simplex virus (hsv) infection was undertaken to characterize the clinical manifestations of the disease and effects of topical therapy with nonoxynol 9, a nonionic surfactant active in vitro against hsv. the duration of pain, lesions, and virus shedding was significantly longer in initial than in recurrent genital hsv infection. cervical hsv shedding occurred in 11 of 13 initial infections versus two of 19 recurrences ... | 1979 | 375733 |
| atheroarteriosclerosis induced by infection with a herpesvirus. | atheroarteriosclerosis closely resembling that in humans was induced in normocholesterolemic and hypercholesterolemic chickens by infection with marek's disease herpesvirus (mdv). four comparably sized groups of chickens were used. each group was initially fed a diet relatively poor in cholesterol. group i and ii were inoculated intratracheally at 2 days of age with mdv. at 15 weeks, one group of virus-infected chickens (group ii) and one group of uninfected controls (group iv) were fed a 2% cho ... | 1979 | 382868 |
| wildebeest-associated malignant catarrhal fever in africa: a neoplastic disease of cattle caused by an oncogenic herpesvirus? | 1979 | 389538 | |
| the herpesvirus of sheep pulmonary adenomatosis. | 1979 | 389539 | |
| the pathology of human cardiac transplantation: an assessment after 11 years' experience at groote schuur hospital. | over a period of 11 years, commencing in december 1967, 31 cardiac transplants, 10 orthotopic and 21 heterotopic, were performed at groote schuur hospital. two patients with orthotopic transplants have a long survival, 1 for 7 1/2 and 1 for 9 1/2 years, and 1 with a heterotopic transplant for 4 years. eighteen patients have died, and autopsy was performed from 13 to 623 days postoperatively. rejection of the donor heart was found in 61,1% and was the cause of death in 44,4% of cases. infection, ... | 1979 | 390737 |
| genital herpesvirus infections. | 1979 | 287917 | |
| characterization of the continuous, differentiating myeloid cell line (hl-60) from a patient with acute promyelocytic leukemia. | in a prelminary communication, we described the establishment of a continuous human myeloid cell line (hl-60). here we report the detailed properties of this cell line and document its derivation from the peripheral blood leukocytes of a patient with acute promyelocytic leukemia. as characterized by light and electron microscopy, the predominant cell type in both the fresh and cultured sources is a neutrophilic promyelocyte with prominent nuclear/cytoplasmic asynchrony. up to 10% of the cultured ... | 1979 | 288488 |
| inactivation of a turkey herpesvirus by ultra-violet light. | the sensitivity to inactivation by ultraviolet light of the pb 1 strain of herpesvirus of turkeys (hvt) was determined and compared with the relative sensitivity of pseudo-rabies virus (prv), another member of the herpesvirus group. hvt (pb1) was 6.3 times more resistant than prv when assayed in chick embryo fibroblasts. the survival curve of hvt (strain pb1) had one component and the survival curve of prv had two components. survival curves of hvt and prv in chick embryo fibroblasts treated wit ... | 1979 | 18770421 |
| differences between early and late membrane antigens on cultured cells infected with herpesvirus of turkeys. | the synthesis of membrane antigen (ma) and intracellular antigen (ia) in arginine-deficient cultures infected with herpesvirus of turkeys (hvt) and their antigenic relationships were examined. by the indirect immunofluorescence test, two kinds of ma were detected using anti-hvt chicken serum [early appearing ma (ema) and late appearing ma (lma)], but few ia positive cells were detected. absorption of the serum by ma positive cells resulted in reduction of reactivity to ma but not to ia. differen ... | 1979 | 18770424 |
| anti-viral immunity against marek's disease virus infected chicken kidney cells. | the mechanism of immunity conferred by herpesvirus of turkeys (hvt) was investigated using marek's disease virus (mdv)-infected chicken kidney cell (ckc) cultures as target cells. peripheral blood lymphocytes (pbl) from normal or hvt-vaccinated chickens killed mdv-infected target cells in the presence of anti-mdv or anti-hvt serum, whereas normal lymphocytes and hvt-sensitised lymphocytes themselves had no specific cytotoxic effect. cell-mediated cytotoxicity of pbl from hvt-vaccinated chicken w ... | 1979 | 18770425 |