Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| evaluation of the sealing capability of implants to titanium and zirconia abutments against porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum under different screw torque values. | when evaluating long-term implant success, clinicians have always been concerned with the gap at the implant-abutment junction, where bacteria can accumulate and cause marginal bone loss. however, little information regarding bacterial leakage at the implant-abutment junction, or microgap, is available. | 2014 | 24656409 |
| effect of estradiol on planktonic growth, coaggregation, and biofilm formation of the prevotella intermedia group bacteria. | alterations in the quantity and quality of biofilms at gingival margin are considered to play a role in the initiation and development of pregnancy-related gingivitis. prevotella intermedia sensu lato is able to consume estradiol, the major sex hormone secreted during pregnancy, in the absence of vitamin k. the aim of the study was to examine the effect of estradiol on the planktonic growth, coaggregation, polysaccharide production, and biofilm formation of the p. intermedia group bacteria, name ... | 2014 | 24594108 |
| prevotella intermedia induces severe bacteremic pneumococcal pneumonia in mice with upregulated platelet-activating factor receptor expression. | streptococcus pneumoniae is the leading cause of respiratory infection worldwide. although oral hygiene has been considered a risk factor for developing pneumonia, the relationship between oral bacteria and pneumococcal infection is unknown. in this study, we examined the synergic effects of prevotella intermedia, a major periodontopathic bacterium, on pneumococcal pneumonia. the synergic effects of the supernatant of p. intermedia (pisup) on pneumococcal pneumonia were investigated in mice, and ... | 2014 | 24478074 |
| preservation of bacterial dna by human dentin. | the capacity of dentin and collagen to bind dna and protect against spontaneous and nuclease-induced degradation was evaluated individually and by the incubation of dna with nuclease-producing bacteria in a mixed culture. | 2014 | 24461411 |
| progression of periodontal inflammation in adolescents is associated with increased number of porphyromonas gingivalis, prevotella intermedia, tannerella forsythensis, and fusobacterium nucleatum. | the study aims to evaluate the change of related subgingival periodontopathogens among different stage of gingivitis in adolescent and assess the relationship between periodontopathogens and the progression of periodontal inflammation. | 2014 | 24025042 |
| susceptibility of methacrylate-based root canal filling to degradation by bacteria found in endodontic infections. | to present a case of endodontic failure obturated with a methacrylate-based root filling material, resilon/realseal (rs). to determine if rs is susceptible to biodegradation by endodontically relevant microbes by a method known to show rs degradation. | 2014 | 25019109 |
| photodynamic therapy versus ultrasonic irrigation: interaction with endodontic microbial biofilm, an ex vivo study. | photodynamic therapy was introduced as an adjuvant to conventional chemo-mechanical debridement during endodontic treatment to overcome the persistence of biofilms. the aim of this study was to evaluate the ability of photodynamic therapy (pdt) to disrupt an experimental microbial biofilm inside the root canal in a clinically applicable working time. | 2014 | 24583092 |
| metronidazole and amoxicillin as adjuncts to scaling and root planing for the treatment of type 2 diabetic subjects with periodontitis: 1-year outcomes of a randomized placebo-controlled clinical trial. | to evaluate the clinical and microbiological effects of the use of metronidazole (mtz) + amoxicillin (amx) as adjuncts to scaling and root planing (srp) for the treatment of chronic periodontitis (chp) in type 2 diabetic subjects. | 2014 | 24930639 |
| antibiotic resistance in human chronic periodontitis microbiota. | patients with chronic periodontitis (cp) may yield multiple species of putative periodontal bacterial pathogens that vary in their antibiotic drug susceptibility. this study determines the occurrence of in vitro antibiotic resistance among selected subgingival periodontal pathogens in patients with cp. | 2014 | 23688097 |
| oxidative stress and antibody levels to periodontal bacteria in adults: the nagasaki islands study. | periodontitis is a chronic inflammatory disease of the tissues supporting the teeth and is caused by subgingival plaque. systemic increases in reactive oxygen species are involved in pathogenesis of periodontitis. this study addressed the relationship between levels of serum oxidative stress and antibodies against putative periodontopathic bacteria and their association with periodontal conditions, in a community-based study. | 2014 | 23679350 |
| anabolic steroids affect human periodontal health and microbiota. | this study aims to evaluate periodontal microbiological differences between systemically healthy nonsmoker males taking anabolic androgenic steroids (aass) and non-aas users and to find associations between disease severity and aas use. | 2014 | 24221579 |
| the effect of il-4 gene polymorphisms on cytokine production in patients with chronic periodontitis and in healthy controls. | chronic periodontitis (cp) is an inflammatory disease of the teeth-supporting tissues in which genetic predisposition, dental plaque bacteria, and immune mechanisms all play important roles. the aim of this study was to evaluate the occurrence of il-4 gene polymorphisms in chronic periodontitis and to investigate the association between polymorphisms and cytokines production after bacterial stimulation. sixty-two subjects (47 cp patients and 15 healthy controls) with detected two polymorphisms i ... | 2014 | 25530681 |
| prevalence of six periodontal pathogens in subgingival samples of italian patients with chronic periodontitis. | the aim of this study was to investigate the subgingival prevalence of six periodontal pathogens in 352 italian patients with chronic periodontitis. possible correlations with clinical parameters, age, gender and smoking status were also investigated. at first visit a pooled subgingival plaque sample was obtained for each subject by using the paper-point method. the samples were processed and analysed according to a commercially available quantitative real time polymerase chain reaction assay (m ... | 2014 | 25387289 |
| opposite effect of supernatants from selected periopathogens and oral lactobacilli cultures on atp levels in human gingival fibroblasts. | studies were performed on the effects of supernatants obtained from bacterial cultures, including cultures of porphyromonas gingivalis, aggregatibacter actinomycetemcomitans, prevotella intermedia and lactobacillus acidophilus strains on atp levels in human gingival fibroblasts (hgf-1) and on their viability. atp levels were evaluated using luminescence test and cell viability was estimated using a fluorescence test. in control cultures mean levels of atp in hgf-1 amounted to 4.90±0.32 mln rlu. ... | 2014 | 25387288 |
| effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. | short chain fatty acids (scfas) play important roles in periodontal diseases. however, the concentrations of scfas in gingival crevicular fluid of patients with aggressive periodontitis are not known. the aim of this intervention study was to investigate the influences of non-surgical periodontal therapy on levels of scfas in the gingival crevicular fluid of patients with generalized aggressive periodontitis (g-agp), and analyze the concentrations of scfas in sites with or without the detected p ... | 2014 | 25340203 |
| evaluation of adjunctive systemic doxycycline with non-surgical periodontal therapy within type 2 diabetic patients. | to evaluate the effects of systemic doxycycline on clinical and microbiological parameters of diabetic subjects with chronic periodontitis. | 2014 | 25316464 |
| detection of periodontal pathogens in the patients with aortic aneurysm. | the occurrence and development of aortic aneurysm (aa) are associated with infection. some researchers have detected the dna of periodontal pathogens in aa samples in certain populations. however, it has not been done in chinese population. the objective of this study was to evaluate the prevalence of periodontal pathogens in oral tissue samples and aneurysm samples of aa patients. | 2014 | 25430459 |
| antibodies to periodontal pathogens are associated with coronary plaque remodeling but not with vulnerability or burden. | previous studies have suggested positive associations between periodontal infection and cardiovascular disease. we aimed to investigate the associations of circulating antibodies against periodontal pathogens with 1-year cardiovascular outcome, as well as the extent of coronary atherosclerosis, plaque vulnerability and lesion remodeling on intravascular ultrasound (ivus) imaging. | 2014 | 25233105 |
| clinical and microbiological characterization of localized aggressive periodontitis: a cohort study. | localized aggressive periodontitis (lagp) is an infectious periodontal disease which generally affects young people. recent data suggest the involvement of different bacterial species in different populations. the causative bacterial species in israel has never been identified despite a high prevalence of lagp in this population. the objectives of this study were to characterize the bacterial microbiota of periodontal pockets within an israeli lagp population who were also clinically assessed. | 2014 | 24861390 |
| evaluation of periodontal pathogens of the mandibular third molar pericoronitis by using real time pcr. | the aim of this study was to investigate the mandibular third molar pericoronitis flora by using real-time polymerase chain reaction (pcr). | 2014 | 24835305 |
| high incidence of periodontitis in japanese patients with abdominal aortic aneurysm. | periodontitis is known to be a risk factor for abdominal aortic aneurysm (aaa). however, the influence of periodontitis on aaa in japanese patients has not yet been elucidated. the aim of this clinical investigation was to assess the relationship between periodontal bacterial burden in aaa patients.we studied 12 aaa patients and 24 age- and sex-matched non-aaa cardiovascular patients. we examined periodontitis and the presence of the periodontal pathogens porphyromonas gingivalis, aggregatibacte ... | 2014 | 24806388 |
| periodontitis in cardiovascular disease patients with or without marfan syndrome--a possible role of prevotella intermedia. | although periodontitis is a risk factor for cardiovascular disease (cvd), the influence of periodontitis on marfan syndrome (mfs) with cvd is unclear. the aim of this study was to assess the relationship between periodontal bacterial burden and msf with cvd. | 2014 | 24748407 |
| rare case of generalised aggressive periodontitis in the primary dentition. | generalised aggressive periodontitis (ap) in the prepubescent age is an exceptionally rare disease in the primary dentition of otherwise healthy children. characteristics of ap are gingival inflammation, deep periodontal pockets, bone loss, tooth mobility and even tooth loss. the most common way of treating this disease is the extraction of all the involved primary teeth. | 2014 | 25001360 |
| periodontal pathogens in atheromatous plaque. | there has been increasing attention paid in recent years to the possibility that oral bacterial infection, particularly periodontal disease may influence the initiation and or progression of systemic diseases. these studies confirm the observation that heart disease is the most commonly found systemic condition in patients with periodontal disease. moreover, the literature has also highlighted substantial evidence indicating the presence of gram-negative periodontal pathogens in atheromatous pla ... | 2014 | 24943760 |
| combinatorial effects of amoxicillin and metronidazole on selected periodontal bacteria and whole plaque samples. | the aim of the present study was to analyze in vitro the combinatorial effects of the antibiotic combination of amoxicillin plus metronidazole on subgingival bacterial isolates. | 2014 | 24727003 |
| [clinical and microbiological effects of the initial periodontal therapy]. | periodontitis is a destructive inflammatory disease of the tooth-supporting tissues, primarily caused by gram-negative microorganisms. thus, the primary objective of cause-related initial periodontal therapy is disruption and removal of the subgingival biofilm. | 2014 | 24684025 |
| in vivo effectiveness of silicone gel sheets as barriers at the inner microgap between a prosthetic abutment and an external-hexagon implant platform. | bacterial penetration and colonization of the microgap at the implant-abutment interface have been reported in several studies. the aim of this study was to evaluate the effectiveness of placing a silicone membrane between the abutment and the implant platform in an attempt to seal the interface. | 2014 | 24451862 |
| effects of adjunctive daily phototherapy on chronic periodontitis: a randomized single-blind controlled trial. | the purpose of this randomized single-blind controlled trial was to elucidate the clinical and antimicrobial effects of daily phototherapy (pt) as an adjunct to scaling and root planing (srp) in patients with chronic periodontitis. | 2014 | 25568808 |
| oral bacterial dna findings in pericardial fluid. | we recently reported that large amounts of oral bacterial dna can be found in thrombus aspirates of myocardial infarction patients. some case reports describe bacterial findings in pericardial fluid, mostly done with conventional culturing and a few with pcr; in purulent pericarditis, nevertheless, bacterial pcr has not been used as a diagnostic method before. | 2014 | 25412607 |
| association between periodontal condition and subgingival microbiota in women during pregnancy: a longitudinal study. | in this study, the gingival conditions and the quantitative detection for aggregatibacter actinomycetemcomitans, fusobacterium nucleatum, porphyromonas gingivalis and prevotella intermedia in pregnant women were determined. | 2014 | 25591021 |
| association between polycystic ovary syndrome, oral microbiota and systemic antibody responses. | polycystic ovary syndrome (pcos) is a hormonal disorder of women that not only is the leading cause of infertility but also shows a reciprocal link with oral health. this study aimed to investigate the hypothesis that the levels of putative periodontal pathogens in saliva and their antibody response in serum are elevated in pcos, compared to systemic health. a total of 125 women were included in four groups; 45 women with pcos and healthy periodontium, 35 women with pcos and gingivitis, 25 syste ... | 2014 | 25232962 |
| the presence of cariogenic and periodontal pathogens in the oral cavity of one-year-old infants delivered pre-term with very low birthweights: a case control study. | recently, the dental literature has focused mainly on the microbial colonization of healthy full-term infants and their mothers or caretakers. however, oral microbial acquisition by premature infants has not been adequately investigated, and the correlation between pre-term birth and the presence of cariogenic and periodontal pathogens has not been determined. the aim of this study was to identify the presence and quantities of representative cariogenic and periodontal pathogens in the oral cavi ... | 2014 | 25178742 |
| prevalence of clinical periodontitis and putative periodontal pathogens among south indian pregnant women. | in view of recent understanding of the association of periodontal infections and adverse pregnancy outcomes, the present investigation was undertaken to study the periodontal infections among 390 asymptomatic pregnant women and to find an association of bacterial etiologies with the disease. prevalence of gingivitis was 38% and clinical periodontitis was 10% among the study population. subgingival plaque specimens were subjected to multiplex pcr targeting ten putative periodontopathogenic bacter ... | 2014 | 24899898 |
| subgingival bacteria in ghanaian adolescents with or without progression of attachment loss. | this study describes subgingival bacterial profiles associated with clinical periodontal status in ghanaian adolescents with or without progression of attachment loss. | 2014 | 24834145 |
| the influence of orthodontic fixed appliances on the oral microbiota: a systematic review. | to investigate whether there is scientific evidence to support the hypothesis that the presence of orthodontic fixed appliances influences the oral microbiota. | 2014 | 24945514 |
| transcriptional responses of treponema denticola to other oral bacterial species. | the classic organization by socransky and coworkers categorized the oral bacteria of the subgingival plaque into different complexes. treponema denticola, porphyromonas gingivalis and tannerella forsythia are grouped into the red complex that is highly correlated with periodontal disease. socransky's work closely associates red with orange complex species such as fusobacterium nucleatum and prevotella intermedia but not with members of the other complexes. while the relationship between species ... | 2014 | 24505483 |
| clinical evaluation of salivary periodontal pathogen levels by real-time polymerase chain reaction in patients before dental implant treatment. | periodontal pathogens in dental plaque are the main causative agents of periodontitis and peri-implantitis. detection of the presence of such periodontal pathogens early would serve as a useful tool in the diagnosis and treatment of this disease. therefore, the purpose of this study was to investigate whether the periodontal pathogen levels in saliva were correlated with the periodontal status of patients receiving implant treatment. | 2014 | 23745964 |
| high-level antimicrobial efficacy of representative mediterranean natural plant extracts against oral microorganisms. | nature is an unexplored reservoir of novel phytopharmaceuticals. since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. therefore, the rationale of the present report was to examine the antimicrobial impact of mediterranean natural extracts on oral microorganisms. five different extracts from olea europaea, mastic gum, and inula viscosa were tested against ten bacteria and one candida albicans s ... | 2014 | 25054150 |
| [antibacterial activity of synthetic antimicrobial decapeptide against oral bacteria]. | this study aims to evaluate the antimicrobial activity of decapeptide, a novel antimicrobial peptide, against several major cariogenic and periodontopathogenic bacteria in vitro. methods in this study, we investigated the antimicrobial activity of decapeptide against streptococcus mutans (s. mutans), streptococcus sobrinus, lactobacillus acidophilus, streptococcus sanguis, streptococcus gordonii, actinomyces viscosus, actinomyces naeslundii, porphyromonas gingivalis, prevotella intermedia, fusob ... | 2014 | 25665430 |
| antibiofilm efficacy of photosensitizer-functionalized bioactive nanoparticles on multispecies biofilm. | newer disinfection strategies based on antibacterial nanoparticles and photodynamic therapy (pdt) aim to eliminate residual biofilm bacteria during root canal treatment. the aim of the current study was to test the newly developed rose bengal-functionalized chitosan nanoparticles (csrbnps) for their interaction/uptake with monospecies bacteria/biofilm and assess their antibiofilm efficacy on a multispecies biofilm model in vitro. | 2014 | 25260731 |
| dental caries and microbiota in children with black stain and non-discoloured dental plaque. | we aimed to assess caries experience and microbiota in systemically healthy children with black stain (bs) and non-discoloured plaque. | 2014 | 24335143 |
| axenic culture of a candidate division tm7 bacterium from the human oral cavity and biofilm interactions with other oral bacteria. | the diversity of bacterial species in the human oral cavity is well recognized, but a high proportion of them are presently uncultivable. candidate division tm7 bacteria are almost always detected in metagenomic studies but have not yet been cultivated. in this paper, we identified candidate division tm7 bacterial phylotypes in mature plaque samples from around orthodontic bonds in subjects undergoing orthodontic treatment. successive rounds of enrichment in laboratory media led to the isolation ... | 2014 | 25107981 |
| colonisation of gingival epithelia by subgingival biofilms in vitro: role of "red complex" bacteria. | biofilm formation on tooth surface results in colonisation and invasion of the juxtaposed gingival tissue, eliciting strong inflammatory responses that lead to periodontal disease. this in vitro study investigated the colonisation of human gingival multi-layered epithelium by multi-species subgingival biofilms, and evaluated the relative effects of the "red complex" species (porphyromonas gingivalis, tannerella forsythia and treponema denticola). | 2014 | 24949828 |
| microbial analysis of subgingival plaque samples compared to that of whole saliva in patients with periodontitis. | the detection of special bacterial species in patients with periodontitis is considered to be useful for clinical diagnosis and treatment. the collection of subgingival plaque samples is the common way for the determination of periodontopathic bacteria. however, recently, salivary analysis has been discussed as an advantageous future diagnostic method for periodontitis because it offers simple quantitative sampling and the possibility to assess various bacteria. the aim of this cross-sectional s ... | 2014 | 24144271 |
| scaling and root planning, and locally delivered minocycline reduces the load of prevotella intermedia in an interdependent pattern, correlating with symptomatic improvements of chronic periodontitis: a short-term randomized clinical trial. | to evaluate the respective or combinatory efficacy of locally delivered 2% minocycline (mo), and scaling and root planning (srp) by assessing both clinical parameters and the loads of four main periodontal pathogens in treating chronic periodontitis (cp). | 2015 | 26676022 |
| evaluation of the efficacy of a probiotic drink containing lactobacillus casei on the levels of periodontopathic bacteria in periodontitis: a clinico-microbiologic study. | this study was designed to evaluate whether the oral administration of lactobacilli could change the bacterial population in subgingival plaque. | 2015 | 26672414 |
| comparative evaluation of the efficacy of curcumin gel with and without photo activation as an adjunct to scaling and root planing in the treatment of chronic periodontitis: a split mouth clinical and microbiological study. | harnessing mother nature's bountiful remedies for rejuvenation has been in vogue since time immemorial. turmeric contains the polyphenol curcumin in its rhizome. it produces reactive oxygen species (ros) with visible light irradiation as photodynamic therapy (pdt) - which validates its use in the treatment of periodontitis. this study compares curcumin and curcumin pdt as an adjunct to conventional scaling and root planing (srp) with srp alone in the treatment of patients with chronic periodonti ... | 2015 | 26604595 |
| deoxyribonucleic acid probes analyses for the detection of periodontal pathogens. | in clinical microbiology several techniques have been used to identify bacteria. recently, deoxyribonucleic acid (dna)-based techniques have been introduced to detect human microbial pathogens in periodontal diseases. deoxyribonucleic acid probes can detect bacteria at a very low level if we compared with the culture methods. these probes have shown rapid and cost-effective microbial diagnosis, good sensitivity and specificity for some periodontal pathogens in cases of severe periodontitis. | 2015 | 26522598 |
| comparison of riboflavin and toluidine blue o as photosensitizers for photoactivated disinfection on endodontic and periodontal pathogens in vitro. | photoactivated disinfection has a strong local antimicrobial effect. in the field of dentistry it is an emerging adjunct to mechanical debridement during endodontic and periodontal treatment. in the present study, we investigate the effect of photoactivated disinfection using riboflavin as a photosensitizer and blue led light for activation, and compare it to photoactivated disinfection with the widely used combination of toluidine blue o and red light. riboflavin is highly biocompatible and can ... | 2015 | 26469348 |
| [antibacterial effect of the carboxymethyl chitosan zinc peptide on several periodontal pathogens in vitro]. | to determine the antimicrobial effects of carboxymethyl chitosan zinc (cmc-zn(+)) and cmc-zn(+)-peptide (cmc-zn(+)-p) on four kinds of periodontal pathogens. | 2015 | 26564745 |
| a study of the fluorescence characteristics of common cariogenic microorganisms. | to explore the fluorescence characteristics of common cariogenic bacteria: streptococcus mutans, s. sanguis, actinomyces viscosus, prevotella intermedia, lactobacillus acidophilus, and candida albicans. | 2015 | 26064260 |
| oral bacteria in placental tissues: increased molecular detection in pregnant periodontitis patients. | the objective of this study was to identify the dna of oral bacteria in placental samples from women with and without periodontitis who had or had not had preterm births and/or low birthweight (pb/lbw) neonates. | 2015 | 26259070 |
| humoral immune responses to periodontal pathogens in the elderly. | elderly people are thought to be more susceptible to periodontal disease due to reduced immune function associated with aging. however, little information is available on the nature of immune responses against putative periodontal pathogens in geriatric patients. the purpose of this study was to evaluate the serum igg antibody responses to six periodontal pathogens in geriatric subjects. | 2015 | 26550526 |
| molecular analysis of oral bacteria in heart valve of patients with cardiovascular disease by real-time polymerase chain reaction. | structural deficiencies and functional abnormalities of heart valves represent an important cause of cardiovascular morbidity and mortality, and a number of diseases, such as aortic stenosis, have been recently associated with infectious agents. this study aimed to analyze oral bacteria in dental plaque, saliva, and cardiac valves of patients with cardiovascular disease. samples of supragingival plaque, subgingival plaque, saliva, and cardiac valve tissue were collected from 42 patients with hea ... | 2015 | 26632711 |
| incorporation of staphylococci into titanium-grown biofilms: an in vitro "submucosal" biofilm model for peri-implantitis. | staphylococcus spp. are postulated to play a role in peri-implantitis. this study aimed to develop a "submucosal" in vitro biofilm model, by integrating two staphylococci into its composition. | 2015 | 26461083 |
| quantitative pcr analysis of salivary pathogen burden in periodontitis. | our aim was to investigate the value of salivary concentrations of four major periodontal pathogens and their combination in diagnostics of periodontitis. the parogene study included 462 dentate subjects (mean age 62.9 ± 9.2 years) with coronary artery disease (cad) diagnosis who underwent an extensive clinical and radiographic oral examination. salivary levels of four major periodontal bacteria were measured by quantitative real-time pcr (qpcr). median salivary concentrations of porphyromonas g ... | 2015 | 26484315 |
| oral bacteria in pancreatic cancer: mutagenesis of the p53 tumour suppressor gene. | carcinoma of exocrine pancreas is the fourth leading cause of cancer deaths, worldwide. the prevalence of this disease is very high in patients with chronic pancreatitis. orodigestive cancers are frequently seen in patients with periodontitis. these findings suggest that this type of cancer may have some bacterial origins. this study hypothesizes that the peptidyl arginine deaminase (pad) enzymes found in oral bacteria may be responsible for the p53 point mutations that occur in patients with pa ... | 2015 | 26617937 |
| detection and measurement of oral malodor in chronic periodontitis patients and its correlation with levels of select oral anaerobes in subgingival plaque. | oral malodor is generally ascribable to oral microbial putrefaction generating malodorous volatile sulfur compounds. the aim of the present study is to correlate organoleptic recordings with a small handheld portable volatile sulfide monitor and periodontal clinical parameters and correlate the levels of halitosis causing bacteria in plaque between baseline, 1-week, and 1-month. | 2015 | 26604572 |
| porphyromonas gingivalis, aggregatibacter actinomycetemcomitans, and treponema denticola / prevotella intermedia co-infection are associated with severe periodontitis in a thai population. | periodontitis is a polymicrobial infection of tooth-supporting tissues. this cross-sectional study aimed to examine the associations between five target species and severe periodontitis in a thai population. using the cdc/aap case definition, individuals diagnosed with no/mild and severe periodontitis were included. quantitative analyses of aggregatibacter actinomycetemcomitans (aa), porphyromonas gingivalis (pg), tannerella forsythia (tf), treponema denticola (td), and prevotella intermedia (pi ... | 2015 | 26313005 |
| archaea prevalence in inflamed pulp tissues. | archaea have been detected in several ecological niches of the human body such as the large intestine, skin, vagina as well as the oral cavity. at present, archaea are recognized as nonpathogenic microorganisms. however, some data indicate that they may be involved in the etiopathogenesis of several diseases, including intestinal diseases as well as oral diseases: periodontitis, peri-implantitis and endodontitis. in this study, on the basis of 16s rrna gene sequence analysis, we examined whether ... | 2015 | 26557034 |
| a metalloproteinase mirolysin of tannerella forsythia inhibits all pathways of the complement system. | recent reports focusing on virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkable pathogenicity of these species, with special emphasis on their capacity to modulate complement activity. in particular, bacteria-mediated cleavage of c5 and subsequent release of c5a seems to be an important phenomenon in the manipulation of the local inflammatory response in periodontitis. in this study, we present mirolysin, a novel metalloproteinase secreted by tann ... | 2015 | 26209620 |
| periodontal pathogens and tetracycline resistance genes in subgingival biofilm of periodontally healthy and diseased dominican adults. | the objective of this study was to compare the periodontopathogen prevalence and tetracycline resistance genes in dominican patients with different periodontal conditions. | 2015 | 26121972 |
| subgingival microbiome in patients with healthy and ailing dental implants. | dental implants are commonly used to replace missing teeth. however, the dysbiotic polymicrobial communities of peri-implant sites are responsible for peri-implant diseases, such as peri-implant mucositis and peri-implantitis. in this study, we analyzed the microbial characteristics of oral plaque from peri-implant pockets or sulci of healthy implants (n = 10), peri-implant mucositis (n = 8) and peri-implantitis (n = 6) sites using pyrosequencing of the 16s rrna gene. an increase in microbial di ... | 2015 | 26077225 |
| effects of hangeshashinto on growth of oral microorganisms. | oral mucositis (om) in cancer patients induced by chemotherapy or radiotherapy has a significant impact on quality of life, and causes considerable morbidity. oral microorganisms are likely to intensify the inflammatory process and aggravate the formation of ulcers. hangeshashinto (hst), a japanese kampo medicine, has been reported to be effective when used as a gargle for the treatment of om. to clarify the effects of hst on oral microorganisms, we assessed its antimicrobial activity against 27 ... | 2015 | 26170876 |
| periodontitis associated with plasminogen deficiency: a case report. | plasminogen deficiency is a rare autosomal recessive disease, which is associated with aggressive periodontitis and gingival enlargement. previously described treatments of plasminogen deficiency associated periodontitis have shown limited success. this is the first case report indicating a successful therapy approach consisting of a non-surgical supra- and subgingival debridement in combination with an adjunctive systemic antibiotic therapy and a strict supportive periodontal regimen over an ob ... | 2015 | 25971786 |
| laser supported reduction of specific microorganisms in the periodontal pocket with the aid of an er,cr:ysgg laser: a pilot study. | the aim of this study was to evaluate the effectiveness of a radial firing tip of an er,cr:ysgg laser as an adjunct to a nonsurgical periodontal treatment. | 2015 | 25879057 |
| quantitative proteomics reveal distinct protein regulations caused by aggregatibacter actinomycetemcomitans within subgingival biofilms. | periodontitis is an infectious disease that causes the inflammatory destruction of the tooth-supporting (periodontal) tissues, caused by polymicrobial biofilm communities growing on the tooth surface. aggressive periodontitis is strongly associated with the presence of aggregatibacter actinomycetemcomitans in the subgingival biofilms. nevertheless, whether and how a. actinomycetemcomitans orchestrates molecular changes within the biofilm is unclear. the aim of this work was to decipher the inter ... | 2015 | 25756960 |
| comparative genome analysis of prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation. | many species of the genus prevotella are pathogens that cause oral diseases. prevotella intermedia is known to cause various oral disorders e.g. periodontal disease, periapical periodontitis and noma as well as colonize in the respiratory tract and be associated with cystic fibrosis and chronic bronchitis. it is of clinical significance to identify the main drive of its various adaptation and pathogenicity. in order to explore the intra-species genetic differences among strains of prevotella int ... | 2015 | 25765460 |
| bacterial profile of aggressive periodontitis in morocco: a cross-sectional study. | aggressive periodontitis (agp) is one of the most severe forms of periodontal diseases. in morocco, aggregatibacter actinomycetemcomitans has been strongly associated with agp, however limited knowledge is available about the implication of other periodontal pathogens in this entity. therefore, the main aim of this study was to evaluate the composition of the subgingival microbiota in moroccan patients with agp. | 2015 | 25888404 |
| non-conventional therapeutics for oral infections. | as our knowledge of host-microbial interactions within the oral cavity increases, future treatments are likely to be more targeted. for example, efforts to target a single species or key virulence factors that they produce, while maintaining the natural balance of the resident oral microbiota that acts to modulate the host immune response would be an advantage. targeted approaches may be directed at the black-pigmented anaerobes, porphyromonas gingivalis and prevotella intermedia, associated wit ... | 2015 | 25668296 |
| anti-hmuy antibodies specifically recognize porphyromonas gingivalis hmuy protein but not homologous proteins in other periodontopathogens. | given the emerging evidence of an association between periodontal infections and systemic conditions, the search for specific methods to detect the presence of p. gingivalis, a principal etiologic agent in chronic periodontitis, is of high importance. the aim of this study was to characterize antibodies raised against purified p. gingivalis hmuy protein and selected epitopes of the hmuy molecule. since other periodontopathogens produce homologs of hmuy, we also aimed to characterize responses of ... | 2015 | 25658942 |
| microbial flora in chronic periodontitis: study at a tertiary health care center from north karnataka. | periodontitis is a major public health problem in india with a prevalence of 60-80%. if untreated it acts as a risk factor for systemic diseases. data on anaerobic periodontal microflora in the indian population is very scarce. hence, this study was undertaken to know the nature of oral microbiota in chronic periodontitis in this region of india and also the semiquantitative study in pre- and post-treatment group and to determine antibiotic susceptibility pattern for aerobic isolates. | 2015 | 25949060 |
| microbiological assessment of the implant-abutment interface in different connections: cross-sectional study after 5 years of functional loading. | to evaluate the bacterial microflora present inside the implant connection and in the peri-implant sulcus fluid of healthy implants, and to analyze the relationships between these harboring sites for four different implant systems after at least 5 years of functional loading. | 2015 | 24665919 |
| peri-implant response and microflora in organ transplant patients 1 year after prosthetic loading: a prospective controlled study. | a recent study conducted in humans demonstrated for the first time that bone loss in the immediate period after implant insertion before loading did not significantly differ in organ transplant recipients with respect to normal subjects. | 2015 | 24612063 |
| assessment of periodontal and opportunistic flora in patients with peri-implantitis. | to assess the presence of periodontal and opportunistic organisms in patients with peri-implantitis. | 2015 | 24720498 |
| internal bacterial colonization of implants: association with peri-implant bone loss. | the aim of the present longitudinal study was to investigate bacterial colonization of the internal implant cavity and to evaluate a possible association with peri-implant bone loss. | 2015 | 24861845 |
| incidence of periodontitis in japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia. | although there is a link between periodontitis and cardiovascular disease (cvd), the influence of periodontitis on cvd is unclear. the aim of this study was to assess the relationship between periodontal bacterial burden and cvd. we studied 142 patients with tachyarrhythmia (ta) and 25 patients with abdominal aortic aneurysm (aaa). we examined periodontitis and the presence of porphyromonas gingivalis, aggregatibacter actinomycetemcomitans and prevotella intermedia in the patients' saliva and su ... | 2015 | 24736944 |
| real-time pcr quantification of six periodontal pathogens in saliva samples from healthy young adults. | the use of saliva as a diagnostic fluid for the evaluation of periodontal health has gained attention recently. most published real-time pcr assays focused on quantification of bacteria in subgingival plaque, not in saliva. the aims of this study were to develop a real-time pcr assay for quantification of six periodontal pathogens in saliva and to establish a relationship between the amount of dna (fg) and colony-forming unit (cfu). | 2015 | 25217278 |
| periodontopathogens and human β-defensin-2 expression in gingival crevicular fluid from patients with periodontal disease in guangxi, china. | periodontal diseases are often induced by periodontopathogens, which are always exposed to certain innate immune factors in gingival crevicular fluid, including human β-defensin-2 (hbd-2). this study aims to investigate the relationship among periodontopathogens, clinical parameters and hbd-2 expression. | 2015 | 25065393 |
| polymerase chain reaction as a prospect for the early diagnosis and prediction of periodontal diseases in adolescents. | this study was to determine the markers representative of pathogenic periodontal microflora [prevotella intermedia (p.i), tannerella forsythia (t.f) [bacteroides forsythus], treponema denticola (t.d), actinobacillus actinomycetemcomitans (a.a), porphyromonas gingivalis (p.g)] in the dental plaque of adolescents with various degrees of severity of periodontium inflammation. | 2015 | 25266040 |
| effect of bdellovibrio bacteriovorus hd100 on multispecies oral communities. | the predation of bdellovibrio bacteriovorus on different periodontal pathogens has already been described. however, it is necessary to consider the polymicrobial nature of periodontal disease. the current study explores the predation of bdellovibrio on oral pathogens organized in multispecies communities. the effect of the predator was evaluated on in vitro six species communities with microbial culturing. additionally, the effect on ex vivo subgingival plaque and saliva samples from periodontit ... | 2015 | 25252124 |
| distribution of 8 periodontal microorganisms in family members of chinese patients with aggressive periodontitis. | to date, no information on the distribution of periodontal microorganisms among family members of chinese patients with aggressive peridontitis (agp) is available. the aim of the present study was to investigate the probability of transmission of eight periodontal microorganisms between patients with aggressive periodontitis and their family members. | 2015 | 25526624 |
| regulation of adrenomedullin and nitric oxide production by periodontal bacteria. | in periodontitis the host response to bacterial challenge includes activity of the multifunctional molecules adrenomedullin (am) and nitric oxide (no). the aim of this study was to investigate the role of periodontal bacteria in regulating the production of these molecules from cultured cells. | 2015 | 25440112 |
| alcohol consumption and periodontitis: quantification of periodontal pathogens and cytokines. | there are few studies on periodontal status related to microbiologic and immunologic profiles among individuals not or occasionally using alcohol and those with alcohol dependence. the aim of this study is to determine the effect of alcohol consumption on the levels of subgingival periodontal pathogens and proinflammatory cytokines (interleukin [il]-1β and tumor necrosis factor [tnf]-α) in the gingival fluid among individuals with and without periodontitis. | 2015 | 26062839 |
| periodontal pathogens participate in synovitis in patients with rheumatoid arthritis in clinical remission: a retrospective case-control study. | the objective of this study was to investigate the role of periodontal pathogens in ra in remission. | 2015 | 26248812 |
| antimicrobial effects of citrus sinensis peel extracts against periodontopathic bacteria: an in vitro study. | use of plant extracts and phytochemicals with known antimicrobial properties may have great significance in therapeutic treatments. | 2015 | 26024407 |
| quantitation of biofilm and planktonic life forms of coexisting periodontal species. | complexity of oral polymicrobial communities has prompted a need for developing in vitro models to study behavior of coexisting bacteria. little knowledge is available of in vitro co-growth of several periodontitis-associated species without early colonizers of dental plaque. | 2015 | 25926392 |
| occurrence of periodontal pathogens in ethnic groups from a native brazilian reservation. | the present study was designed to evaluate the occurrence of periodontal pathogens in the subgingival biofilm of 100 native brazilians living at the umutina indian reservation, mato grosso state, brazil. | 2015 | 25847068 |
| short-term effect of removal of fixed orthodontic appliances on gingival health and subgingival microbiota: a prospective cohort study. | the aim of this prospective longitudinal study was to assess and compare the microbiological and clinical parameters of patients wearing a fixed orthodontic appliance, as opposed to 10 days after the bracket had been removed following treatment. | 2015 | 25631494 |
| anti-inflammatory, antioxidant and antimicrobial effects of artemisinin extracts from artemisia annua l. | the anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of artemisia annua l. were evaluated. all 4 artemisinin-containing extracts had anti-inflammatory effects. of these, the acetone extract had the greatest inhibitory effect on lipopolysaccharide-induced nitric oxide (no), prostaglandin e2 (pge2), and proinflammatory cytokine (il-1β , il-6, and il-10) production. antioxidant activity evaluations revealed that t ... | 2015 | 25605993 |
| microbial leakage at the implant-abutment connection due to implant insertion maneuvers: cross-sectional study 5 years postloading in healthy patients. | the aim of this study was to test if stress on the prosthetic connection during insertion maneuvers can induce micro-warping at the implant connection. from september 2011 to july 2013, patients with implants loaded for at least 5 years that were placed with 2 different insertion implant mounters-mp (conventional) and me (mountless)-were selected from all of those who had received dental implant therapy in the past and were attending routine check-up or spontaneous visits during the study period ... | 2015 | 25536224 |
| periodontopathogen and epstein-barr virus-associated periapical periodontitis may be the source of retrograde infectious peri-implantitis. | herpesviral-bacterial synergism may play a role in periodontitis and peri-implantitis etiopathogenesis. periapical periodontitis (pp) lesions can predict future apical peri-implantitis complications. | 2015 | 23675952 |
| [fungal invasion of connective tissue in patients with gingival-periodontal disease]. | in the last few years unusual microorganisms have been isolated from subgingival biofilm, as possible initiators or contributors to periodontal disease, especially in patients who show no improvement during treatment. | 2015 | 22824245 |
| antimicrobial effectiveness of cetylpyridinium chloride and zinc chloride-containing mouthrinses on bacteria of halitosis and peri-implant disease. | to clarify the antimicrobial efficacy of zinc chloride (zncl2) and cetylpyridinium chloride (cpc) by testing their impact on the growth of seven bacterial strains known to be involved in the pathophysiology of both peri-implant disease and halitosis-staphylococcus aureus, streptococcus mutans, porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum, treponema denticola, and tannerella forsythia. | 2015 | 26478974 |
| extensive description and comparison of human supra-gingival microbiome in root caries and health. | knowledge of the polymicrobial etiology of root caries is limited. to conduct a comprehensive research study on root caries, we utilized 454-pyrosequencing of 16s rrna gene libraries and quantitative pcr to compare supra-gingival bacterial communities from healthy sites and carious sites of 21 patients with root caries (patient-controls and patient-cases) and the sites of 21 healthy individuals (healthy-controls) from two nursing homes. healthy-controls and patient-cases showed no significant di ... | 2015 | 25658087 |
| phototargeting human periodontal pathogens in vivo. | the effects of blue light at 455 nm were investigated on the bacterial composition of human dental plaque in vivo. eleven subjects who refrained from brushing for 3 days before and during phototherapy participated in the study. light with a power density of 70 mw/cm(2) was applied to the buccal surfaces of premolar and molar teeth on one side of the mouth twice daily for 2 min over a period of 4 days. dental plaque was harvested at baseline and again at the end of 4 days from eight posterior tee ... | 2015 | 24346334 |
| [noma/cancrum oris: a neglected disease]. | noma is an aggressive orofacial gangrenous pathology that damages hard and soft tissues of the mouth and the face. throughout the centuries it has been present around the globe, but nowadays it has practically disappeared from developed countries and mainly affects children from the most disadvantaged places, especially in africa. noma disease is a multifactorial process; malnutrition, debilitating diseases (bacterial or viral systemic diseases, hiv-associated immunosuppression, etc.) and intrao ... | 2015 | 26437752 |
| identification of an antibacterial protein by functional screening of a human oral metagenomic library. | screening of a bacterial artificial chromosome (bac) library containing metagenomic dna from human plaque and saliva allowed the isolation of four clones producing antimicrobial activity. three of these were pigmented and encoded homologues of glutamyl-trna reductase (glutr), an enzyme involved in the c5 pathway leading to tetrapyrole synthesis, and one clone had antibacterial activity with no pigmentation. the latter contained a bac with an insert of 15.6 kb. initial attempts to localize the ge ... | 2015 | 26347298 |
| evaluation of anti-microbial activity of spore powder of ganoderma lucidum on clinical isolates of prevotella intermedia: a pilot study. | this study aimed at evaluating the anti-microbial activity of spore powder of ganoderma lucidum on prevotella intermedia isolated from subgingival plaque from chronic periodontitis patients. | 2015 | 26604581 |
| bioinformatic investigation of the cost management strategies of five oral microbes. | some amino acids are more energetically costly to synthesize de novo, therefore many microbes have evolved to regulate the metabolic expenditure of the cell and reduce the energy burden of extracellular unrecyclable proteins. several oral bacterial species take up amino acids and peptides obtained from proteolysis of host proteins and hence do not rely only on de novo synthesis. the aim of this study was to investigate if five oral bacterial species implement cost management strategies to reduce ... | 2015 | 25052707 |