Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
microbial flora in orodental infections.the present study was carried out to compare the normal aerobic and anaerobic bacterial oral flora with flora from deep seated dental caries, gingivitis and adult periodontitis. all the samples belonging to both the control and study groups yielded microbes. aerobe / anaerobe ratio was high in normal flora (1.48) as compared to dental caries (0.9), gingivitis (0.72) and periodontitis (0.56). ninety seven percent of orodental infections were polymicrobial and three or more microbes were found in ...200317642993
anaerobes in bacterial vaginosis.four hundred high vaginal swabs were taken from patients attending gynaecology and obstetrics department of govt. medical college, amritsar. the patients were divided into four groups i.e. women in pregnancy (group i), in labour/post partum (group ii), with abnormal vaginal discharge or bacterial vaginosis (group iii) and asymptomatic women as control (group iv). anaerobic culture of vaginal swabs revealed that out of 400 cases, 212(53%) were culture positive. maximum isolation of anaerobes was ...200317642997
role of anaerobes in acute pelvic inflammatory disease.pouch of douglas aspirates were collected from 50 women with history and examination suggestive of acute pelvic inflammatory disease (pid) and 20 healthy women admitted for tubal ligation served as control. a total of 57 microorganisms were isolated from 37 patients out of 50 in study group. of 37 positive cultures 21(56.7%) were monomicrobial and 16(43.2%) were polymicrobial. most common symptom in study group was lower abdominal pain (90%), vaginal discharge (70%) and irregular bleeding (40%) ...200317643017
an in vitro time-kill assessment of linezolid and anaerobic bacteria.linezolid is a novel oxazolidinone antibacterial agent active against staphylococci (including methicillin-resistant strains), enterococci (including vancomycin-resistant strains), streptococci (including penicillin-intermediate and -resistant streptococcus pneumoniae), and other aerobic and facultative bacteria. the agent has also demonstrated activity against a broad spectrum of gram-positive and gram-negative anaerobic bacteria. previous time-kill assessments have shown linezolid to be genera ...200316887680
antibiotic susceptibility of clinically relevant anaerobes in estonia from 1999 to 2001.at present little or no data is available regarding the resistance profiles of anaerobic bacteria in relation to the general usage of antibiotics. the objective of this study was to assess whether any potential relationship exists between the dynamics of antibiotic resistance of anaerobic bacteria and the consumption of antibiotics during the last 3 years within the estonian population. in total, 416 anaerobic isolates were investigated from various clinical samples. the anaerobes were isolated ...200316887688
anaerobic bacteria cultured from the tongue dorsum of subjects with oral malodor.the bacteria on the dorsum of the tongue are the most frequent cause of oral malodor; however, the bacterial flora of the tongue has not been well defined. although recent studies have used dna probes to detect the presence of certain periodontal pathogens, cultural studies have been limited because of the complexity of the flora of the tongue dorsum. the purpose of this study was to grow and to identify maximum numbers of capnophylic gram-negative bacilli and anaerobic micro-organisms by cultur ...200316887710
e-test antibiotics susceptibility of strict anaerobic bacteria.the e-test is convenient for testing susceptibility of anaerobes. from september 1998 to september 1999, 194 strains (105 gram-positive bacteria, 89 gram-negative bacteria) of clinically relevant samples were tested against five antibiotics benzylpenicillin, amoxicillin-clavulanic acid, clindamycin, metronidazole and imipenem on blood agar plates. resistance to benzyl penicillin is widespread and gram-negative bacteria and resistance to amoxicillin-clavulanic acid is exceptional. metronidazole i ...200316887712
zygomatic abscess complicating a huge mastoid cholesteatoma with intact eardrum. 200312646852
anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro.anaerobic cocci are estimated to be present in the deep tissues of over 50% of chronic skin wounds. while the part they play in the chronicity of these wounds is uninvestigated, anaerobic cocci have previously been shown to be involved in other chronic inflammatory human conditions.200312653737
evaluation of root canal microorganisms isolated from teeth with endodontic failure and their antimicrobial susceptibility.studies of the microbiota from the canals of teeth with failure of endodontic therapy have revealed that it differs markedly from that of untreated necrotic dental pulps. this study aimed to evaluate the microbiota of 30 root-filled teeth with persisting periapical lesions and to test the antibiotic susceptibility of the most prevalent species. microbial samples, isolation and speciation were done using advanced microbiologic techniques for anaerobic species. a total of 55 bacterial species were ...200312654099
bactericidal activities of methoxyfluoroquinolones gatifloxacin and moxifloxacin against aerobic and anaerobic respiratory pathogens in serum.gatifloxacin (bristol-myers squibb) and moxifloxacin (bayer) are new methoxyfluoroquinolones with broad-spectrum activity against aerobic and anaerobic pathogens of the respiratory tract. in this investigation, we analyzed the bactericidal activity in serum over time of these antimicrobials against three aerobic (streptococcus pneumoniae, haemophilus influenzae, and staphylococcus aureus) and four anaerobic (peptostreptococcus micros, peptostreptococcus magnus, fusobacterium nucleatum, and prevo ...200312654663
microorganisms from canals of root-filled teeth with periapical lesions.the objective of the present study was to identify the microbial flora within root canals of teeth with failed root-canal treatment and to determine the association of the various species with clinical features.200312656508
an immunohistological study of the localization of bacteria invading root pulpal walls of teeth with periapical lesions.we immunohistologically examined the prevalence and localization of bacteria invading dentinal tubules of the roots of teeth with infected canals. forty extracted teeth with apical lesions were selected and divided into two groups: a group of untreated teeth and a group of canal-enlarged teeth. the bacteria in the specimens were detected by brown-brenn stain and the labeled-streptavidin-biotin method with specific antisera for 16-bacteria. seventy percent of the examined teeth showed bacteria in ...200312669880
antimicrobial properties of self-etching primer-bonding systems.self-etching primers are now considered the new generation of dentin bonding systems that modify and incorporate the bacteria-containing smear layer into their bonding mechanism. the antibacterial effects of the self-etching primers clearfil se bond, mac bond, imperva fl bond, one-up bondf and prompt l-pop were evaluated using the bacteria streptococcus mutans atcc25175, peptostreptococcus anaerobius, peptostreptococcus prevotii, peptostreptococcus asaccharolyticus, lactobacillus acidophilus, la ...200312670069
transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.after anaerobic incubation of arctiin (1) from the seeds of arctium lappa with a human fecal suspension, six metabolites were formed, and their structures were identified as (-)-arctigenin (2), (2r,3r)-2-(3',4'-dihydroxybenzyl)-3-(3",4"-dimethoxybenzyl)butyrolactone (3), (2r,3r)-2-(3'-hydroxybenzyl)-3-(3",4"-dimethoxybenzyl)butyrolactone (4), (2r,3r)-2-(3'-hydroxybenzyl)-3-(3"-hydroxy-4"-methoxybenzyl)butyrolactone (5), (2r,3r)-2-(3'-hydroxybenzyl)-3-(3",4"-dihydroxybenzyl)butyrolactone (6), and ...200312672988
specific pcr detection of peptostreptococcus magnus.peptostreptococcus magnus is the most pathogenic and one of the most common gram-positive anaerobic cocci found in human clinical specimens. the organism has been isolated in pure culture from a range of serious infections, including meningitis and endocarditis. however, isolation of peptostreptococcus magnus from the oral cavity has rarely been attempted. identification of peptostreptococcus magnus in clinical specimens is reliant upon microbiological culture and biochemical methods, which ofte ...200312676869
ultrastructural analysis of an infected collagen-coated vascular graft.the incidence of infection following arterial reconstruction using synthetic graft materials varies from less than 1 to 5%. one of three mechanisms is thought to be responsible: 1. intraoperative contamination, 2. extension from adjacent infected or colonized tissue, or 3. hematogenous or lymphogenous seeding. we present ultrastructural data of a patient with a polymicrobial graft infection due to a prostheto-enteric fistula 16 years after reconstruction of an aortobifemoral graft. the polymer s ...200312677763
differences in antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinse formulations: an in vitro contact test and salivary bacterial counts study.to evaluate the in vitro and in vivo antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinses.200312694428
microbiology and management of acute suppurative thyroiditis in children.this review describes the microbiology, diagnosis and management of suppurative thyroiditis (st). staphylococcus aureus, streptococcus pyogenes, streptococcus epidermidis, and streptococcus pneumoniae, are the predominant aerobic isolates. the most common anaerobic bacteria are gram-negative bacilli and peptostreptococcus spp. agents that are rarely recovered include klebsiella spp., haemophilus influenzae, streptococcus viridans, salmonella spp., enterobacteriaceae, mycobacterium tuberculosis, ...200312697345
microbiology and management of intra-abdominal infections in children.the present review describes the microbiology, diagnosis, and management of intra-abdominal infections in children. infection generally occurs due to the entry of enteric micro-organisms into the peritoneal cavity through a defect in the wall of the intestine or other viscus as a result of obstruction, infarction, or direct trauma. mixed aerobic and anaerobic flora can be recovered from the peritoneal cavity of these patients. the predominant aerobic isolates are escherichia coli, and enterococc ...200312709135
in vitro and in vivo antibacterial activities of telithromycin.telithromycin is one of the ketolides, characterised by a 3-keto group instead of l-cladinose and a c(11)-c(12) carbamate link by an alkyl chain to a pyridinum and imidazolium ring side chain. we evaluated in vitro and in vivo antibacterial activities of telithromycin against gynaecological pathogens.200312714813
[extrinsic ureteral obstruction secondary to inflammatory gynecologic pathology].to present two cases of extrinsic ureteral obstruction secondary to gynaecological inflammatory diseases, and to perform a bibliographic review.200312731448
bacterial penetration through canals of endodontically treated teeth in the presence or absence of the smear layer.the goal of this study is to determine if the smear layer affects the passage of bacteria through or around obturating material as evidenced by penetration of bacteria through and out the canal. specifically, this study focused on determining the effect of the smear layer on the magnitude of bacterial penetration through the apical foramen.200312735922
the effects of a triclosan/copolymer dentifrice on oral bacteria including those producing hydrogen sulfide.a clinical procedure was developed to examine the effects of short-term and extended use of a triclosan/copolymer dentifrice and a commercial fluoride dentifrice on oral bacteria, including those producing hydrogen sulfide. healthy adults volunteered for this double-blind, crossover design clinical study and provided saliva samples for culturing on enriched and indicator media to enumerate all salivary bacteria and those producing hydrogen sulfide (odorigenic), respectively. subjects brushed wit ...200312786953
comparative in vitro activity of ph-027 versus linezolid and other anti-anaerobic antimicrobials against clinical isolates of clostridium difficile and other anaerobic bacteria.ph-027 is a new 5-triazole oxazolidinone synthesized in our laboratories, which shows strong activity against gram-positive aerobic bacteria including clinical isolates. the objective of this study was to investigate the in vitro activity of this compound in comparison with linezolid and other antibiotics against gram-positive and gram-negative anaerobes. the in vitro activity of ph-027 in comparison with those of linezolid and other antimicrobial agents was evaluated against 201 clinical isolat ...200312797385
endocarditis due to peptostreptococcus anaerobius: case report and literature review of peptostreptococcal endocarditis.infective endocarditis caused by anaerobic streptococci occurs rarely, and only five cases have been described in detail, with two additional cases mentioned in a review of anaerobic infective arthritis. all have resulted from infection caused by peptostreptococci. another case of anaerobic gram-positive endocarditis caused by peptostreptococcus anaerobius has recently been encountered. the patient was successfully treated with a beta-lactam for six weeks, plus gentamicin (to which the organism ...200312803344
increased antimicrobial resistance in organisms recovered from otitis media with effusion.previous studies concerning the microbiology of otitis media with effusion (ome) did not correlate the past use of antimicrobial agents with the recovered organism's antimicrobial susceptibility. a retrospective analysis of cultures obtained from aspirates of 129 children with ome was performed. the study identified the isolated organisms and determined their susceptibility to the most recently administered antimicrobials. bacterial growth was noted in 58 (45 per cent) patients. aerobic organism ...200312818052
antibacterial activity of medicinal plant extracts against periodontopathic bacteria.this study was performed to evaluate the antibacterial activity of althaea officinalis l. roots, arnica montana l. flowers, calendula officinalis l. flowers, hamamelis virginiana l. leaves, illicium verum hook. fruits and melissa officinalis l. leaves, against anaerobic and facultative aerobic periodontal bacteria: porphyromonas gingivalis, prevotella spp., fusobacterium nucleatum, capnocytophaga gingivalis, veilonella parvula, eikenella corrodens, peptostreptococcus micros and actinomyces odont ...200312820224
in vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, bacitracin, and four other antimicrobials against intestinal anaerobic bacteria.by using an agar dilution method, the in vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, and five other agents were determined against 300 gram-positive and 54 gram-negative strains of intestinal anaerobes. ramoplanin was active at <or=2 microg/ml against 287 of 300 (95.7%) gram-positive organisms, including 18 strains of clostridium difficile for which mics of ramoplanin were 0.25 to 0.5 microg/ml; for 3 of these, linezolid mics were 8 to 16 micro g/ml. nineteen clostridium ...200312821492
[bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between april 2001 and march 2002].isolated bacteria from infections in general surgery during the period from april 2001 to march 2002 were investigated in a multicenter study in japan, and the following results were obtained. in this series, four hundred and twenty strains were isolated from 175 (79.2%) of 221 patients with surgical infections. one hundred and eighty-six strains were isolated from primary infections, and 234 strains were isolated from postoperative infections. from primary infections, anaerobic gram-positive ba ...200312825413
effect of smoking and periodontal treatment on the subgingival microflora.the effect of smoking on the prevalence of periodontal pathogens after periodontal treatment is still not clear. some studies found no effect of the smoking status on the prevalence of periodontal pathogens after therapy, whereas others did. the aim of this retrospective study was to investigate the influence of smoking on the treatment of periodontitis and the composition of the subgingival microflora.200312834497
antibiotic susceptibilities of gram-positive anaerobic cocci: results of a sentinel study in england and wales.a sentinel study was carried out to determine the antimicrobial susceptibilities of gram-positive anaerobic cocci (gpac) freshly isolated from clinical material in diagnostic laboratories in england and wales.200312837734
in vitro activities of telithromycin and 10 oral agents against aerobic and anaerobic pathogens isolated from antral puncture specimens from patients with sinusitis.a study of the comparative in vitro activity of telithromycin, a new ketolide, against 155 aerobic and 171 anaerobic antral sinus puncture isolates showed it to be active against a broad range of sinus pathogens. all pneumococci, including erythromycin-resistant strains, were susceptible to telithromycin at < or = 0.5 microg/ml; all haemophilus influenzae and eikenella corrodens strains were inhibited by < or = 4 microg of telithromycin/ml; all moraxella spp. and beta-lactamase-producing prevote ...200312760875
in vitro activities of dalbavancin and nine comparator agents against anaerobic gram-positive species and corynebacteria.dalbavancin is a novel semisynthetic glycopeptide with enhanced activity against gram-positive species. its comparative in vitro activities and those of nine comparator agents, including daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin, against 290 recent gram-positive clinical isolates strains, as determined by the nccls agar dilution method, were studied. the mics of dalbavancin at which 90% of various isolates tested were inhibited were as follows: actinomyces spp., 0.5 microg ...200312760876
[utility of anaerobic blood cultures in extra-hospitalary bacteremias].to compare the rentability of anaerobic hemocultures with aerobic cultures in patients suffering bacteremia, trying to analyze the rentability of anaerobic cultures.200312768830
immunoglobulin-binding domains: protein l from peptostreptococcus magnus.protein l is a multidomain cell-wall protein isolated from peptostreptococcus magnus. it belongs to a group of proteins that contain repeated domains that are able to bind to igs without stimulating an immune response, the most characterized of this group being protein a ( staphylococcus aureus ) and protein g ( streptococcus ). both of these proteins bind predominantly to the interface of c(h)2-c(h)3 heavy chains, while protein l binds exclusively to the v(l) domain of the kappa -chain. the fun ...200312773190
[early diagnosis of bacterial brain abscesses: interest of diffusion-weighted mri].three cases of bacterial brain abscesses, in immunocompetent patients, are reported. in all these cases, the diffusion-weighted magnetic resonance (mri) with apparent diffusion coefficient (adc) map has permitted an early diagnosis and a rapid treatment. this emergency mri showed in the three cases a low signal on ti-weighted images, a high signal on t2-weighted and echo-planar images, and a decrease of adc (0.36- 0.49 x 10(-3) mm2/s). so, this new mri technique provides an available and rapid e ...200312773871
deep neck infection: a present-day complication. a retrospective review of 83 cases (1998-2001).deep neck infections are less and less frequent today than in the past. nevertheless, their complications are often life-threatening. the present study reviews the experience of the department of otolaryngology and head and neck surgery of padua with deep neck infections during the period from 1998 to 2001. eighty-three patients (55 males and 28 females) were retrospectively considered. the site of origin of deep neck infection was identified in 76 patients (91%). the most common cause was denta ...200312774234
additive antimicrobial activity of calcium hydroxide and chlorhexidine on common endodontic bacterial pathogens.it is an established procedure to use calcium hydroxide [ca(oh)2] as a therapeutic component to achieve sterilization of infected root canals. unfortunately, some bacterial species are relatively resistant to ca(oh)2 and are therefore associated with treatment failures. the objective of this study was to identify combinations of substances that improve antimicrobial activity. ca(oh)2 was used as a suspension or as a component of gutta-percha points. efficacy of killing was compared for (a) ca(oh ...200312775007
late infection in patients with scoliosis treated with spinal instrumentation.sixty patients were treated using a multilevel spinal instrumentation system. spine arthrodesis was done posteriorly in all patients using a combination of two rods, hooks, screws, and cross-link plates. the galveston technique was used in three patients. five patients presented with late deep wound infections 1 to 5 years postoperatively. two patients presented with a local subcutaneous abscess, whereas the remaining patients had a local drainage. exploration revealed pus lining the instrumenta ...200312782866
[megaesophagus microbiota and carcinogenesis].the risk of development of spin cell carcinoma of the esophagus is 33 times higher in patients with chagasic achalasia. it is possible that the production of n-nitroso compounds in the esophageal lumen by of bacterial action in the stasis liquid that reduce nitrates from diet into nitrites may play a role in this process.200314534659
microbial dynamics of purulent nasopharyngitis in children.this review presents the microbiological dynamic and therapeutic options in the management of purulent nasopharyngitis (npt). the nasopharynx (np) of healthy children is generally colonized by relatively non-pathogenic aerobic and anaerobic organisms, some of, which possess the ability to interfere with the growth of potential pathogens. conversely, carriage of potential respiratory aerobic pathogen such as streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis, as well as so ...200314550957
[yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--i. gram-positive bacteria].the in vitro antibacterial activities of cefozopran (czop), an agent of cephems, against various clinical isolates obtained between 1996 and 2001 were yearly evaluated and compared with those of other cephems, oxacephems, carbapenems, and penicillins. a total of 1,274 strains in 15 species of gram-positive bacteria were isolated from the clinical materials annually collected from january to december, and consisted of methicillin-susceptible staphylococcus aureus (mssa), methicillin-resistant sta ...200314567254
fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis.the cases of five patients with fusobacterial brain abscess are presented. the authors discuss their attempt to determine the pathogenesis.200314567605
fermentation of five sucrose isomers by human dental plaque bacteria.sucrose has five structural isomers: palatinose, trehalulose, turanose, maltulose and leucrose. although these isomers have been reported to be noncariogenic disaccharides, which cannot be utilized by mutans streptococci, there is no information about their fermentability by other bacteria in dental plaque. the purpose of the present study was to examine whether these isomers were fermented by predominant bacteria in human dental plaque. clinical bacterial isolates obtained from dental plaque fr ...200314571118
ct of a ruptured pyomyoma. 200314573437
[anaerobic bacteria in bronchoalveolar lavage fluid (bal) after thoracic surgery].purpose of this study was to find out what kind of anaerobic bacteria were in lower respiratory tract and how often they were present there considering patients after thoracic surgery. also, what is susceptibility of bacteria to antibiotics. research covered 30 patients after operation. material for research was bronchoalveolar lavage (bal) taken during bronchoscopy. collected sample was cultivated in anaerobic and aerobic conditions. anaerobic bacteria were found in 28 samples (93%). totally th ...200314577197
[the presence of bacteria and yeast like fungi in specimens from surgical patients].the aim of this study was to determine the incidence of candida spp. strains in specimens obtained from surgically treated patients as well as to analyze the accompanying bacterial flora, both aerobic and anaerobic. the material came from two groups of patients. in the first group consisting of patients operated for colon and rectum carcinoma, the samples included peritoneal fluid, colon or rectum bioptates, pus, blood, and wound swabs. in the other group, biopsy material and smears from post op ...200314577199
importance of sequence specificity for predicting protein folding pathways: perturbed gaussian chain model.recent experimental and theoretical studies suggest that rates and pathways of protein folding are largely decided by topology of the native structures, at least for small proteins. however, some exceptions are known; for example, protein l and protein g have the same topology, but exhibit different characteristics of the tse. thus, folding pathways of some proteins are critically affected by detailed information on amino acid sequences. to investigate the sequence specificity, we calculate fold ...200314579353
distribution of periodontal pathogens in korean aggressive periodontitis.microbial associations in aggressive periodontitis versus different ethnic origins are substantially unknown. we undertook this study to determine the prevalence of seven putative periodontopathogens in korean patients and to evaluate microbial differences in localized and generalized aggressive periodontitis patients.200314584866
infection-associated hemophagocytic syndrome in a diabetic patient undergoing chronic hemodialysis.hemophagocytic syndrome (hps) is an uncommon but severe illness associated with a variety of infections, malignant tumors, and autoimmune diseases. we report a case of infection-associated hps in a patient receiving chronic hemodialysis. peptostreptococcus-induced sepsis and abscess formation in the left iliopsoas muscle led to the onset of infection-associated hps in this patient. the patient had diabetes mellitus and end-stage renal disease, and it is likely that immunological dysfunctions fro ...200314586736
planning of empirical antibiotic therapy for women with pelvic inflammatory diseases: a geographical area-specific study.elaboration of an empiric antibiotic regimen for women with pelvic inflammatory disease (pid) for a geographical area in eastern hungary.200314597249
microbiology and management of endodontic infections in children.the first step in the origination of caries is the formation of a dental plaque. dental caries can lead to destruction of enamel and dentin resulting in bacterial invasion of the pulp. invasion of the pulp and the periapical areas can promote the development of dento-alveolar abscess and spread of the infection to other anatomical areas. several oral acid producing aerobic and anaerobic bacteria, including streptococcus mutans, lactobacillus acidophilus, and actinomyces viscosus, are capable of ...200314604136
bacteriologic findings in patients with chronic sinusitis.we studied the bacteriology of maxillary sinus aspirates obtained from patients diagnosed with chronic sinusitis. we recovered 659 strains from 510 aspirates; of these, 572 (86.8%) were aerobes and 87 (13.2%) were anaerobes. aerobes only were recovered from 310 of the 510 specimens (60.8%) and anaerobes only from 31 (6.1%). among the 572 aerobic bacteria, the most prevalent organisms were streptococcus viridans (158 strains [27.6%]), streptococcus pneumoniae (67 [11.7%]), corynebacterium species ...200314606178
clinical presentation and bacteriologic analysis of infected human bites in patients presenting to emergency departments.previous studies of infected human bites have been limited by small numbers of patients and suboptimal microbiologic methodology. we conducted a multicenter prospective study of 50 patients with infected human bites. seventy percent of the patients and assailants were young adult men. fifty-six percent of injuries were clenched-fist injuries and 44% were occlusional bites. most injuries were to the hands. fifty-four percent of patients were hospitalized. the median number of isolates per wound c ...200314614671
la, ptb, and pab proteins bind to the 3(') untranslated region of norwalk virus genomic rna.noroviruses are human enteric caliciviruses for which no cell culture is available. consequently, the mechanisms and factors involved in their replication have been difficult to study. in an attempt to analyze the cis- and trans-acting factors that could have a role in nv replication, the 3(')-untranslated region of the genome was studied. use of zuker's mfold-2 software predicted that nv 3(')utr contains a stem-loop structure of 47 nts. proteins from hela cell extracts, such as la and ptb, form ...200314623338
normal ocular features, conjunctival microflora and intraocular pressure in the canadian beaver (castor canadensis).the aim of the study was to assess the ocular features, normal conjunctival bacterial and fungal flora, and intraocular pressure (iop) in the canadian beaver (castor canadensis).200314641823
fak deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.targeted deletion of focal adhesion kinase (fak) in the developing dorsal forebrain resulted in local disruptions of the cortical basement membrane located between the neuroepithelium and pia-meninges. at disruption sites, clusters of neurons invaded the marginal zone. retraction of radial glial endfeet, midline fusion of brain hemispheres, and gliosis also occurred, similar to type ii cobblestone lissencephaly as seen in congenital muscular dystrophy. interestingly, targeted deletion of fak in ...200314642275
rapid identification of gram-positive anaerobic coccal species originally classified in the genus peptostreptococcus by multiplex pcr assays using genus- and species-specific primers.here, a rapid and reliable two-step multiplex pcr assay for identifying 14 gram-positive anaerobic cocci (gpac) species originally classified in the genus peptostreptococcus (anaerococcus hydrogenalis, anaerococcus lactolyticus, anaerococcus octavius, anaerococcus prevotii, anaerococcus tetradius, anaerococcus vaginalis, finegoldia magna, micromonas micros, peptostreptococcus anaerobius, peptoniphilus asaccharolyticus, peptoniphilus harei, peptoniphilus indolicus, peptoniphilus ivorii and pepton ...200312855723
effect of amoxicillin or clindamycin on the adenoids bacterial flora.we sought to compare the effect on the adenoid bacterial flora of patients with recurrent otitis media of antimicrobial therapy with amoxicillin (am) or clindamycin (c). patients and methods forty-five children scheduled for elective adenoidectomy participated in a prospective randomized study. they were divided into 3 groups of 15 each to receive either no therapy (control) or 10 days of therapy with am or c. core adenoid tissues was quantitatively cultured for aerobic and anaerobic bacteria.200312869909
extensive subgaleal abscess and epidural empyema in a patient with acute frontal sinusitis.acute frontal sinusitis can be a serious condition because of its potential life-threatening complications. these complications, including spread of infection to the frontal bone and intracranially, require prompt diagnosis and intervention to avoid morbidity and mortality. we report a case of acute frontal sinusitis in a 16-year-old girl who presented with fever, severe headache, and vomiting of 3 days' duration. generalized fluctuant swelling of the nasal root, and bilateral supraorbital and f ...200312874674
positive and negative bacterial associations involving dialister pneumosintes in primary endodontic infections.dialister pneumosintes is an anaerobic gram-negative rod that has been recently implicated as a candidate endodontic pathogen. in this study, samples taken from abscessed teeth and infected root canals associated with asymptomatic or symptomatic periradicular lesions were examined for the occurrence of bacterial associations involving d. pneumosintes. dna was extracted from the samples, and the presence of d. pneumosintes and 16 other bacterial species was determined by means of species-specific ...200312877258
antibiotic resistance of pathogenic bacteria from odontogenic infections in taiwan.the purpose of this study was to evaluate the susceptibility of facultative and anaerobic odontogenic infectious flora to various antibiotics. we assessed 178 bacterial strains isolated from 74 patients with odontogenic infections. the e-test was used to determine susceptibility. the microbial flora was predominantly facultative gram-positive organisms and anaerobic gram-negative bacilli. the results of antimicrobial susceptibility test showed that ampicillin resistance was found with a very hig ...200312886961
subgingival microflora in turkish patients with periodontitis.no information exists on periodontitis-associated subgingival microbiota from turkey. we determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a turkish study population.200312886990
[outbreak of tropical phagedenic ulcers after the rainy season in dijibouti].the incidence of cutaneous ulcers was observed after the rainy season in djibouti in 1997. based on the study of epidemiologic, clinical, biological, and therapeutic features these lesion were classified as phagedenic ulcers. while direct examination showed numerous fusiform bacilli, cultures performed in one patient, led to isolation of numerous colonies of prevotella loescheii. though less common, two other anaerobic bacterial species were detected, i.e., peptostreptococcus anaerobius and pept ...200312910663
microbiology and management of chronic suppurative otitis media in children. 200312929878
coronal microleakage assessed by polymicrobial markers.studies have shown significant bacterial leakage following exposure of sealed root canals to artificial and natural saliva. the objective of this study was to determine contamination via bacterial migration in artificial saliva in endodontically treated teeth using different obturation techniques and sealers. a total of 144 extracted, human mandibular anterior teeth were cleaned and shaped to a #40 master apical file using hand and rotary instrumentation. one hundred and twenty teeth were divide ...200312937592
[cerebral abscesses of oral origin].it has been suggested that between 3% and 13% of the cerebral abscesses (ca) are presumably associated to oral infections or dental procedures.200312938049
identification of oral peptostreptococcus isolates by pcr-restriction fragment length polymorphism analysis of 16s rrna genes.oral peptostreptococcus isolates tentatively identified by conventional microbiological culture methods were identified to the species level by a combination of pcr amplification of 16s rrna genes and restriction enzyme analysis of the amplified products. this method is a reliable and rapid alternative to conventional methods for identification of these bacterial species.200312958299
[evaluation of anaerobic flora in lung neoplasms].purpose of this study was to analyse the kind and frequency of anaerobic bacteria in the lower respiratory tract as well as susceptibility of the bacteria to antibiotics. material from 35 patients with lung tumour derived from tumour and post-tumoural area sample. collected sample was cultivated in anaerobic and aerobic conditions. anaerobic bacteria were found in 23 (66%) samples. totally there were 44 isolated of anaerobic bacteria strains. the most common g-negative strains belonged to genus ...200312959024
[incidence of anaerobic bacteria in respiratory tract infections].anaerobic bacteria are predominant components of normal oral cavity, upper respiratory tract, gastrointestinal, genital and skin flora. they are involved in infections such as pneumonia, aspiration pneumonia, lung abscess and empyema. laboratory diagnosis of anaerobic infections is based on recovering the etiological agents from clinical materials. appropriatte specimens include: pus, purulent fluid, biopsy specimen of lung, transtracheal aspirates and bronchoalveolar lavage (bal). lower respira ...200312959026
[modifying action of oxytocin on the biological properties of the causative agents of anaerobic non-clostridial infection].in a number of in vitro experiments the effect of oxytocin on the antilysozyme and anticomplemental activity of propiobacterium propionicum, bacteroides fragilis, prevotella melaninogenica and peptostreprtococcus anaerobius, isolated from patients with acute pyoinflammatory pleuropulmonary diseases, was studied. antibiotic resistance dynamics of the infective agents under study to lincomycin, clindamycin, thienam, vancomycin was also detected. the inhibiting activity of oxytocin on the persisten ...200312966884
[effect of a polyoxydonium immunoregulator on the biological properties of microorganisms].the effect of the synthetic immunomodulator polyoxydonium (po) on some biological properties of pathogenic bacteria (shigella flexneri, salmonella enteritidis), opportunistic bacteria (klebsiella pneumoniae, escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, bacteroides fragilis, peptostreptococcus anaerobius, prevotella melaninogenica, propionibacterium propionicum, clostridium difficile) and fungi (candida albicans), isolated during enteric infections, enteric dysbiosis, pyoinfla ...200312966885
endocarditis caused by finegoldia magna (formerly peptostreptococcus magnus): diagnosis depends on the blood culture system used.we present a patient with prosthetic valve endocarditis caused by finegoldia magna (formerly peptostreptococcus magnus). blood cultures in the bact/alert and bactec 9240 system were negative. we therefore tested different blood culture systems: f. magna grew in the septi-chek bhi-s and in the isolator, but not in the bact/alert system.200312967750
six cases of bacterial infection in porous orbital implants.we present 6 cases of bacterial infection that developed after porous orbital implant surgery.200312967870
bacteriological study of root canals associated with periapical abscesses.the aim of this study was to identify microorganisms from root canals with periapical abscesses and to ascertain the susceptibility of peptostreptococcus prevotii and fusobacterium necrophorum to antimicrobials. study design thirty root canals were microbiologically sampled by using sterile paper points. the concomitant microorganisms were identified through the use of established methods. the susceptibility of p prevotii and f necrophorum to antimicrobials was evaluated by using the e test meth ...200312973290
[comparative in vitro activity of ertapenem against aerobic and anaerobic bacteria].the in vitro activity of ertapenem (mk-0826), a new carbapenem, was studied against 389 aerobic microorganisms (187 enterobacteriaceae, 15 aeromonas spp., 42 staphylococcus spp., 43 streptococcus spp., 15 enterococcus spp., 30 haemophilus spp., 15 moraxella catarrhalis, 12 neisseria gonorrhoeae, 15 pseudomonas aeruginosa and 15 acinetobacter spp.) and 54 anaerobic isolates (15 clostridium spp., 12 peptostreptococcus spp. and 27 fragilis group bacteroides recovered from four spanish hospitals. er ...200312973459
faropenem, a new oral penem: antibacterial activity against selected anaerobic and fastidious periodontal isolates.the in vitro activity of faropenem, an oral penem, was compared with those of penicillin, co-amoxiclav, cefoxitin, clindamycin, erythromycin and metronidazole against 106 isolates of anaerobic pathogens involved in systemic infections. the organisms tested comprised porphyromonas gingivalis (29), prevotella spp. (eight), prevotella melaninogenica (seven), prevotella intermedia (five), actinomyces spp. (25), fusobacterium nucleatum (14), peptostreptococcus spp. (11), bacteroides ureolyticus (five ...200312615878
[brain abscesses after extracranial infections of the head and neck area].the authors report on 20 immunocompetent patients with brain abscess after 12 cases of middle ear, seven tooth and a single frontal sinus infection. the clinical aspects, hematochemical and microbiological data, the role of imaging diagnostics (ct, mr) and the type of treatment are analysed. neurosurgery was performed on 17 patients (85%), eight of whom subsequently underwent evacuation of the primary source of infection (four mastoidectomies, two timpanoplasties, two tooth extractions). mastoid ...200314523535
[surveillance of susceptibility of clinical isolates to cefmetazole between 2000 and 2002].the antibacterial activity of cefmetazole (cmz) against clinical isolates from 15 medical institutions all over japan was evaluated yearly for two years from june 2000 to march 2002 and compared with that of other parenteral beta-lactams, cefazolin (cez), cefotiam (ctm), sulbactam/cefoperazone (sbt/cpz), and flomoxef (fmox). in the first surveillance from june 2000 to march 2001, 575 isolates of 13 species were tested, and 548 isolates of the same 13 species were tested in the second surveillanc ...200315007873
[antibacterial activity of oral cephems against various clinically isolated strains].we determined the antibacterial activities of oral cephems against isolated from the patients with the respiratory infections, the urinary tract infections, and infections in the obstetrics field of an adult and a child, during the period from 2002 to 2003; streptococcus pyogenes, streptococcus pneumoniae, haemophilus influenzae, branhamella catarrhalis, klebsiella pneumoniae and escherichia coli of 40 strains of each, and peptostreptococcus spp. 22 strains. s. pneumoniae and h. influenzae strai ...200315007876
characteristics of anaerobes from skin specimens.anaerobes isolated from skin specimens from 1999 to 2001 were examined. the most common type was peptostreptococcus spp., especially p. magnus and p. assaccharolyticus and bacteroides fragilis. dominance was seen for p. magnus, p. acnes and p. prevotii. peptostreptococcus spp. and p. acnes showed high susceptibility to four antimicrobial agents. prevotella spp. and b. fragilis showed low or no susceptibility to ampicillin, while b. fragilis showed low susceptibility to ceftizoxime. evaluation of ...200315018306
[post-marketing surveillance of antibacterial activities of cefozopran against various clinical isolates--i. gram-positive bacteria].as a post-marketing surveillance, the in vitro antibacterial activities of cefozopran (czop), an agent of cephems, against various clinical isolates were yearly evaluated and compared with those of other cephems, oxacephems, penicillins, and carbapenems. changes in the bacterial susceptibility for czop were also evaluated with the resistance ratio calculated with breakpoint mic. sixteen species (2,363 strains) of gram-positive bacteria were isolated from the clinical materials annually collected ...200314692380
bacterial artificial chromosome library of finegoldia magna atcc 29328 for genetic mapping and comparative genomics.we constructed a bacterial artificial chromosome (bac) library of finegoldia magna atcc 29328 dna to facilitate further genome analysis of f. magna. the bac library contained 385 clones with an average insert size of 55 kb, representing a 10.1-fold genomic coverage. repeated dna hybridization using primer sets designed on the basis of bac-end sequences yielded nine contigs covering 95% of the chromosome and two contigs covering 98% of the plasmid. the contigs were localized on the physical map o ...200314695451
inflammatory polyp in the middle ear with secondary suppurative meningoencephalitis in a cat.a 15-month-old male maine coon cat presented with persistent auricular discharge and progressive head tilt, ataxia, and loss of blink on the right side. using computed tomography a hyperattenuating, contrast-enhancing material within a thickened right tympanic bulla and contrast enhancement of the adjacent cerebellum were identified. marked suppurative inflammation was identified on cerebrospinal fluid analysis with no growth on bacterial culture. ventral bulla osteotomy was performed to remove ...200314703245
antibiotic susceptibility of bacterial isolates in gingivitis and periodontitis.the present study was conducted to isolate aerobic as well as anaerobic microbes from patients of gingivitis and adult periodontitis and to study the susceptibility patterns of these isolates to different antibiotics. in our study all the samples belonging to the control as well as the study groups yielded microbes. aerobes and facultative anaerobes were isolated from 100 percent and 96 percent cases of normal gingiva and orodental infections respectively. anaerobes were isolated from 80 percent ...200314705453
comparison of ligand polarization and enzyme activation in medium- and short-chain acyl-coenzyme a dehydrogenase-novel analog complexes.spectroelectrochemical and off-resonance raman indicate that substrate/product binding to medium-chain acyl-coenzyme a (coa) dehydrogenase (pmcad) results in ligand polarization and positive flavin potential shifts, which activate the enzyme for electron transfer. bacterial short-chain acyl-coa dehydrogenase (bscad) typically exhibits smaller potential shifts upon substrate/product binding that have not been linked to ligand polarization. to further investigate the roles of ligand binding and po ...200312504892
immunoglobulin superantigen protein l induces il-4 and il-13 secretion from human fc epsilon ri+ cells through interaction with the kappa light chains of ige.peptostreptococcus magnus protein l is a multidomain bacterial surface protein that correlates with virulence. it consists of up to five homologous ig-binding domains (b1-b5) that interact with the variable domain of ig kappa l chains. intact protein l stimulates the synthesis and the release of il-4 and il-13 from human basophils in vitro. a protein l fragment covering the ig-binding domains b1-b4 also induced il-4 and il-13 release from basophils. there was an excellent correlation (r(s) = 0.8 ...200312574351
effects of selected immunouppressive drugs on prostaglandin release, protein synthesis and cell proliferation in human gingival fibroblasts and on the growth of plaque bacteria.immunosuppressants play an essential role in transplantation therapy. in view of the side effects, e.g. gingival overgrowth, the present in vitro study was performed in order to investigate the effect of selected immunosuppressants on metabolic activities of gingival fibroblasts. furthermore, the effect on the growth of six oral microorganisms was investigated.200312578751
peptostreptococcus micros in primary endodontic infections as detected by 16s rdna-based polymerase chain reaction.a 16s rdna-based polymerase chain reaction (pcr) method was used to detect peptostreptococcus micros in primary root canal infections. samples were collected from 50 teeth having carious lesions, necrotic pulps, and different forms of periradicular diseases. dna extracted from the samples was amplified using the pcr assay, which yielded a specific fragment of p. micros 16s rdna. p. micros was detected in 6 of 22 root canals associated with asymptomatic chronic periradicular lesions (27.3%), 2 of ...200312597709
activities of garenoxacin (bms-284756) and other agents against anaerobic clinical isolates.a total of 590 clinical isolates consisting of 33 species of both gram-positive and gram-negative anaerobes were collected from nine centers in the chicago area in 1998-1999. the largest number of isolates (330 isolates, 56%) belonged to the bacteroides group. isolates were tested by agar dilution against garenoxacin (bms-284756, t-3811 me), trovafloxacin, moxifloxacin, clindamycin, imipenem, piperacillin-tazobactam, and cefoxitin. all but one species (2% of bacteroides vulgatus isolates) were f ...200312604521
dna from periodontopathogenic bacteria is immunostimulatory for mouse and human immune cells.although bacterial dna (bdna) containing unmethylated cpg motifs stimulates innate immune cells through toll-like receptor 9 (tlr-9), its precise role in the pathophysiology of diseases is still equivocal. here we examined the immunostimulatory effects of dna extracted from periodontopathogenic bacteria. a major role in the etiology of periodontal diseases has been attributed to actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and peptostreptococcus micros. we therefore isolated d ...200312540566
acute bacterial suppurative parotitis: microbiology and management.the parotid gland is the salivary gland most commonly affected by inflammation. the most common pathogens associated with acute bacterial parotitis are staphylococcus aureus and anaerobic bacteria. the predominant anaerobes include gram-negative bacilli (including pigmented prevotella and porphyromonas spp.), fusobacterium spp., and peptostreptococcus spp. streptococcus spp. (including s. pneumoniae) and gram-negative bacilli (including escherichia coli) have also been reported. gram-negative or ...200312544218
the microflora recovered from the outer-surfaces of the frialit-2 implanto-prosthetic connector.the aim of the present investigation was to examine the outer-surface microbiota of the prosthetic connector of frialit-2 implants, and to compare the microbial findings with the peri-implant parameters 2 years after functional loading. in 16 implant-treated patients (55.8 +/- 9.5 years) the outer-surface micro-organisms of the prosthetic connectors were determined in 32 frialit-2 implants. the functional loading time of the prosthetic suprastructures was 24.1 +/- 13.8 months on average. after r ...200312562362
bacteremia following surgical dental extraction with an emphasis on anaerobic strains.our aim was to investigate bacteremia caused by surgical extraction of partly erupted mandibular third molars. from 16 young adults, bacterial samples were taken from the third-molar pericoronal pocket and post-operatively from the extraction socket, and blood samples were drawn from the ante-cubital vein up to 30 min after surgery. of the subjects, 88% had detectable bacteremia-50% 1 min after the incision, 44% immediately after extraction. the respective percentages at 10, 15, and 30 min were ...200414742658
presurgical antimicrobial prophylaxis: effect on ocular flora in healthy patients.evaluation of presurgical antimicrobial prophylaxis for reduction of ocular flora.200414756385
microbiological examination of infected dental root canals.the aim of this study was to investigate the root canal microbiota of primary and secondary root-infected canals and the association of constituent species with specific endodontic signs and symptoms.200414871344
in vivo vl-targeted activation-induced apoptotic supraclonal deletion by a microbial b cell toxin.to interfere with host immune responses, some microbial pathogens produce proteins with the properties of superantigens, which can interact via conserved v region framework subdomains of the ag receptors of lymphocytes rather than the complementarity-determining region involved in the binding of conventional ags. in recent studies, we have elucidated how a model b cell superantigen affects the host immune system by targeting a conserved v(h) site on the ag receptors of b lymphocytes. to determin ...200414978088
human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms.human beta-defensins 2 and 3 (hbd-2 and hbd-3) are inducible peptides present at sites of infection in the oral cavity. a few studies have reported broad-spectrum antimicrobial activity for both peptides. however, no comprehensive study has thoroughly investigated their potential against oral pathogens. the purpose of this study was to test the effectiveness of hbd-2 and hbd-3 against a collection of oral organisms (actinobacillus actinomycetemcomitans, fusobacterium nucleatum, porphyromonas gin ...200415004048
cervical spinal epidural abscess and meningitis due to prevotella oris and peptostreptococcus micros after retropharyngeal surgery. 200415034651
Displaying items 1701 - 1800 of 2255