Publications

[the triangular ligaments of the dog].		1978	152067
effects of 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine on the rat central nervous system after intraventricular or intracerebral application and on blood platelets in vitro.		1978	152083
irs, hew threaten triple-a bonds.		1978	152403
[biochemistry of myocardium taken at autopsy. preliminary report].	the findings after biochemical analysis of heart muscle taken at autopsy are given in this preliminary communication. human myosin is made up of two heavy sub-units and two light sub-units: it is similar to cardiac myosin found in other mammals, but is different in certain characteristics, particularly immunological ones. tropomyosin is made up of two different sub-units. the normal human heart contains 1 mg of collagen and 130 microgram of desoxyribonucleic acid (dna) per 100 mg of fresh tissue ...	1978	152617
inhibition of four human serine proteases by substituted benzamidines.	a series of substituted benzamidines has been examined for their inhibitory activity against the human serine proteases--trypsin, thrombin, plasmin, and c1s, a subunit of the first component of complement. the inhibition constants obtained for each enzyme were correlated with physical-chemical properties of the substituent group using the quantitative structure-activity relationship approach. this analysis indicated that plasmin and c1s are very similar in their interactions with substituted ben ...	1978	152812
[receptor adaptation of muscle spindles treated in different ways].	comparison of the grades of 60 sensitive muscle spindle terminals on two actions: gradual stretch of the muscle and short intensive tetanization of the muscle nerve, showed that, irrespective of the mode of action, the character of adaptation remains the smae in majority of units. the speed of receptors adaptation depends not on the specific of testing precedures, but, apparently, on the means of connection of the sensitive terminals with different types of intrafusal muscle fibers with differen ...	1978	153244
immunologic functions and in vitro activation of cultured macrophage tumor lines.	five murine monocyte of macrophage tumor lines adapted to culture were characterized for differentiated properties. they ingested zymosan and latex beads, bore receptors for immunoglobulin and complement, synthesized lysozyme (most of which was secreted), and produced granulocyte colony-stimulating activity, either spontaneously or inducibly. some of the lines also mediated phagocytosis and exocytosis of red blood cells (rbc) and lysis of tumor targets, dependent on the presence of specific anti ...	1978	107454
[preparation of extracellular ribonuclease from bacillus subtilis].	the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ...	1978	107517
[induction of macrophage activation with bacterial products for potentiation of resistance to some chronic infections].	adult mice of the consanguine a2g strain received two intraperitoneal inoculations of 0.5 mg listeria monocytogenes phospholipid extract at 30 days interval. in the treated animals and the controls, the capacity to develop a humoral immune response was tested 24 hours after the second inoculation, following antigenic stimulus with sheep red blood cells; phagocytizing in vitro of labelled germs by peritoneal macrophages and the response of lymphocytes to mitogenic and allogenic stimuli were likew ...	1978	107569
enteric infections in singapore with special reference to typhoid.	a review of the epidemiological features of the more important enteric infections in singapore was given. enteric fevers (typhoid and paratyphoid), salmonella gastroenteritis and shigellosis remained endemic at a rather constant level in spite of vast improvement in environmental sanitation, but amoebic dysentery showed marked decline. vibrio parahaemolyticus is an important cause of food poisoning since it was first reported in 1973. el tor cholera is believed to be introduced through regional ...	1978	107597
an enzyme-linked immunosorbent assay (elisa) for detecting chicken anti-reovirus antibody at high sensitivity.	an enzyme-linked immunosorbent assay (elisa) with high sensitivity was developed for use in the avian system. anti-reovirus antibody produced in chickens against the isolants s1133, umi-203, reo-25, and winterfield were detected with this method at high titers (up to 1:14,000).	1978	107949
construction of a recombinant plasmid composed of b. subtilis leucine genes and a b. subtilis (natto) plasmid: its use as cloning vehicle in b. subtilis 168.		1978	105237
the uptake of choline by streptococcus pneumoniae.	uptake of choline, a structural component of pneumococcal c- and f-teichoic acids, into bacteria growing in a defined medium was very efficient with an uptake constant ([s]10 5) of 3.2 microns. it was inhibited by iodoacetate, dinitrophenol and oligomycin but not by structural analogues of choline. ethanolamine, however, was transported in the absence of choline but with a reduced affinity ([s]0.5 71.4 microns). the same constitutive system was probably used by both ethanolamine and choline. it ...	1978	34010
studies on human sexual development. vi. concentrations of unconjugated dehydroepiandrosterone, estradiol, and estriol in amniotic fluid throughout gestation.	concentrations of unconjugated dehydroepiandrosterone, estradiol, and estriol were measured in samples of amniotic fluid from uneventful pregnancies of 9-40 weeks conceptual age. there was no apparent influence of fetal sex upon the levels of these steroids. dehydroepiandrosterone concentrations rose slightly from 9-20 weeks, and then showed little further change. estradiol concentrations declined slightly from 9-20 weeks; after 32 weeks gestation, there was a 2-fold rise to term. estriol levels ...	1978	162521
altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli.	the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ...	1978	98520
identification of low chlorinated biphenyls in human milk by gas chromatography--mass spectrometry.	trichlorobiphenyl and tetrachlorobiphenyls in human milk were analysed by gas chromatography--mass spectrometry and mass fragmentography using silicone ov-1 and apiezon l grease as stationary phases. low-chlorinated biphenyls had been considered to be excreted rapidly from the body, but in this work quantities of tri- and tetrachlorobiphenyls amounting to approximately 30% of the total of polychlorinated biphenyls (pcbs) accumulated in the milk were identified. this result is important in relati ...	1978	98535
rats defend different body weights depending on palatability and accessibility of their food.	normal adult rats lived on powdered diets adulterated to contain as much as 1.6% quinine sulfate, on a palatable high-fat diet, or in skinner boxes with 45-mg noyes pellets available on fixed-ratio (fr) schedules as high as fr 156. they maintained lower body weights over periods of months in proportion to the percentage of quinine adulteration or the fixed ratio. rats exposed to the high-fat diet overate as much and gained weight as rapidly as rats recovering from food deprivation, and became mo ...	1978	98538
high affinity uptake sites for taurine in the retina.		1978	104877
studies on the pathogenesis of hemorrhagic enteritis of turkeys.	the infectivity of turkey hemorrhagic enteritis (he) virus was studied in poults with no detectable maternal antibody and in turkeys bursectomized or injected with killed-virus preparations. poults less than three weeks old were not infected by hemorrhagic enteritis virus, and survivors were susceptible to challenge at the age of eight weeks. three- and four-week-old poults were susceptible to he, and survivors resisted challenge. bursectomy partially interfered with the immune response but did ...	1978	98158
genital inoculation of male macaca fascicularis with neisseria gonorrhoeae and ureaplasma urealyticum.	inoculation of the urethra, conjunctiva, pharynx, and anal canal of six male crab-eating macaques (macaca fascicularis) with urethral exudate from male patients with urethral gonorrhoea or with laboratory gonococcal strains was unsuccessful in establishing infection or producing increased polymorphonuclear leucocytes on gram stain. intraurethral inoculation with laboratory strains of ureaplasma urealyticum resulted in transiently positive urethral cultures for u. urealyticum and was associated i ...	1978	98203
microbial degradation of [c14c]polystyrene and 1,3-diphenylbutane.	microbial degradation of [beta-14c]polystyrene and 1,3-diphenylbutane, a compound structurally representing the smallest repeating unit of styrene (dimer), was investigated in soil and liquid enrichment cultures. degradation rates in soil, as determined by 14co2 evolution from applied [14c]polystyrene, varied from 1.5 to 3.0% for a 4-month period. although relatively low, these percentages were 15 to 30 times greater than values previously reported. enrichment cultures, containing 1,3-diphenylbu ...	1978	98222
relation of nucleosomes to dna sequences.		1978	98278
immunochemical studies on the 5-methylcytosine content of african green monkey satellite dna.		1978	98282
nature of immune complexes formed in rhesus monkeys immunized with pr-beta-hcg-tt on challenge with hcg.		1978	98290
ultrastructural hepatic changes by carbamate pesticide (sevin) in rats.		1978	98323
recruitment order, contractile characteristics, and firing patterns of motor units in the temporalis muscle of monkeys.		1978	98343
fatty liver in experimental protein-energy malnutrition in the rat.		1978	98345
sensitivity of gonococcus strains isolated in rotterdam to epicillin, ampicillin, penicillin and tetracycline.	quantitative determinations of the sensitivity to epicillin, ampicillin, penicillin and tetracycline were carried out for 67 gonococcus strains isolated from 67 males with urogenital gonorrhoea, and 38 strains isolated from 38 females with urogenital/rectal gonorrhoea. the results of the sensitivity determinations for ampicillin, penicillin and tetracycline were compared with the findings of a previous investigation. it was found that the gonococcus strains isolated from males had become slightl ...	1978	98362
calcium-dependent binding of mouse epididymal spermatozoa to the zona pellucida.		1978	98372
radionuclide emission computed tomography of the body of laboratory animals.	selective studies in the monkey and baboon demonstrate the normal physiologic distribution of 99mtc radiopharmaceuticals using single-photon emission computed tomography. the cases demonstrated the ability of the cleon transverse section brain imager tm to do emission computed tomography of various organs. this experience shows what can be expected when equipment for emission computed tomography of the body becomes available for patient studies.	1978	97732
[reservoirs and wild vectors of trypanosoma cruzi. lxviii: infection of mammals by oral route].		1978	97735
benign meningococcemia in childhood. a report of five cases with clinical and diagnostic remarks.	five children aged 1/2--10 years with benign meningococcemia are reported. the clinical picture was quite uniform: good general condition, spikes of fever, skin eruptions as maculopapules--sometimes haemorrhagic, appearing in association with febrile periods, and arthralgia (big joints). the diagnosis involves either isolation of meningococci (mc) from blood, demonstration of mc with immunofluorescence in skin eruptions, or a significant elevation of mc antibody titre in connection with typical ...	1978	97774
isolation care of infection-prone burn patients.	an experimental and clinical study of spread of colonisation between burn patients, and their susceptibility to infection, was performed. burn patients' polymorphonuclear neutrophil granulocytes (pmn) functioned poorly, particularly during the second week after injury which coincided with maximum growth of bacteria in the burn wound. patients with large burns often dispersed s. aureus and ps. aeruginosa but also beta-hemolytic streptococcus to the air of their rooms. airborne transfer of these b ...	1978	97776
detection of antibodies against echinococcus granulosus arc 5 antigens by double diffusion test.	this report deals with an evaluation of a double diffusion (dd5) test which employs a control antiserum against echinococcus granulosus arc 5 antigens to recognize arc 5-positive sera by a reaction of identity. the dd5 test was more sensitive than the immuno-electrophoresis (iep5) test based on the same positivity criterion and was equally specific for the immunodiagnosis of human hydatidosis. its greater simplicity suggest its application as a substitute for the iep5 test in diagnosis, particul ...	1978	97814
post-mortem diagnosis of chronic chagas's disease comparative evaluation of three serological tests on pericardial fluid.	in an attempt to improve the post-mortem diagnosis of chagas's disease the authors performed haemagglutination tests (hat), fluorescent trypanosoma cruzi antibody tests (fat), and complement fixation tests (cft) on the pericardial fluid obtained at autopsy of 50 individuals with chagas's heart disease, and 93 patients in whom this disease was not thought to be present. the results demonstrate that all three tests are efficient for the post-mortem diagnosis of chagas's disease but suggest that th ...	1978	97817
evaluation of endomyocardial biopsy in the diagnosis of cardiac rejection. a study using bioptome samples of formalin-fixed tissue.	the reliability of endomyocardial bioptome samples in detecting cardiac rejection was assessed in 26 formalin-fixed previously transplanted hearts. thirteen human donor hearts (mean postoperative survival 128 days) and 13 baboon donor hearts (mean survival 16.5 days) were studied. twenty samples were taken under direct vision from the endomyocardium of each heart with an olympus bioptome catheter. a total of 397 tissue samples was examined "blindly" histologically (177 human and 220 baboon). the ...	1978	97824
genetics of the idiotype of strain akr antibodies to group a streptococcal carbohydrate; further evidence for a low degree of homology in the vh chromosomal region.	a new vh gene is described which governs the expression of idiotypes associated with the antibody response of strain akr mice to group a streptococcal carbohydrate (a-cho). this vh gene, termed achd, is identified using guinea pig antisera to a pool of strain akr antibodies to a-cho. the genetic polymorphism is revealed by quantitative differences in idiotype expression between different inbred strains. in recombinant inbred strains linkage to the ig-1d allotype allele of strain akr is demonstr ...	1978	97871
[immunological study of cellular components of pseudomonas aeruginosa. iv. fractionation of pseudomonas aeruginosa mucus by diafiltration and biological properties of isolated fractions].	in fractionation of pseudomonas aeruginosa mucus (strains no. 8 and 1463) by means of diafiltration on the system of membranes diaflo xm-300, xm-100a, pm-30, and pm-10 there was obtained a successive series of fractions differing by the molecular weight and chemical composition. according to the results of gel chromatography fractions with the mol wt of 100000 dalton and over apparently represented protein-polysaccharide components of mucus in the form of complexes; fractions with the mol wt of ...	1978	97882
[prospects for the use of blood substitutes made in the ussr with the expired date of validity].	as revealed, blood substitutes--aminopeptide, caseine hydrolysate, and hydrolysine with the expired date of validity could be used as the basis of nutrient media for the cultivation of bacteria. bacterial growth proved to be the optimum in addition to the blood substitutes of a 0.25--0.5% of yeast extract.	1978	97885
[enzyme-histochemical behaviour of the tanycyte ependyma in the iii. ventricle of the rat with thiamin deficiency (author's transl)].	the influence of experimental thiamine deficiency in rats on enzyme-histochemical parameters was carried out in the diencephalon. the degree of thiamine deficiency was measured by the activity coefficient of transketolase in the red blood cells. the alpha-etk of thiamine deficient animals was 1,45 +/- 0,36, of equal-fed animals 1,04 +/- 0.04 and of control animals 1,08 +/- 0,04. we got the following results: lactatdehydrogenase, acid phosphatases and thiamine pyrophosphatase did not indicate any ...	1978	97912
molybdenum independence of nitrogenase component synthesis in the non-heterocystous cyanobacterium plectonema.	the cyanobacterium plectonema boryanum (iu 594-utex 594) fixes n2 only in the absence of combined n and of o2. we induced nitrogenase by transfer to anaerobic n-free medium and studied the effect of mo starvation on nitrogenase activity and synthesis. activity was first detected within 3 h after transfer by the acetylene reduction assay in controls, increasing for at least 25 h. cells grown on nitrate and mo and then transferred to n-free, mo-free medium produced 8% of the control nitrogenase ac ...	1978	96092
dietary restrictions early and late: effects on the nephropathy of the nzb x nzw mouse.	nzb x nzw f1 mice initiated on calorie restriction at weaning or at 4 to 5 months of age or initiated on moderate protein restriction at weaning, were afforded significant protection from the development of immune nephritis. whereas animals on normal calorie intake demonstrated deposition of immune reactants in glomerular basement membrane-oriented pattern, those on either protein or calorie restriction exhibited mesangial confinement of immunoglobulins and complement. associated with these dive ...	1978	96299
[exolipases of some pseudomonas species].	the production of exolipase was studied in various pseudomonas species, most of which did not possess the lipolytic activity in the conditions of the experiment, whereas in some strains this activity was rather high. the highest activity was displayed by the pseudomonas fluorescens 533 strain and its mutant obtained upon uv irradiation. lipase biosynthesis depended on the composition of a growth medium, the highest lipolytic activity being found on media with a high content of complex organic su ...	1978	96317
deprenyl administration in man: a selective monoamine oxidase b inhibitor without the 'cheese effect'.	after pretreatment with the selective monoamine oxidase b inhibitor, (-)-deprenyl, in doses sufficient for complete inhibition of the platelet enzyme, 4 normal and 6 parkinsoniam volunteers (2 receiving levodopa and 2 levodopa plus carbidopa) suffered no adverse pressor reaction ('cheese effect') after challenge with oral tyramine in amounts considerably greater than those likely to be encountered in a normal diet. nor did the levodopa-deprenyl combination itself result in a pressor response. no ...	1978	96466
brain and liver aldehyde dehydrogenase activity and voluntary ethanol consumption by rats: relations to strain, sex, and age.	voluntary ethanol consumption and brain and liver aldehyde dehydrogenase (aldh) activity were measured in male and female rats of the tryon maze-bright (s1), tryon maze-dull (s3), and wistar strains. the levels of brain aldh measured in the different groups, corresponded well to the levels of ethanol consumption, while differences in liver aldh corresponded well to only the strain differences in ethanol intake. within individual groups, levels of ethanol consumption correlated better with levels ...	1978	96475
response of a rat rhabdomyosarcoma to neon- and helium-ion irradiation.		1978	96481
haplotype designations of various strains of guinea pigs.		1978	96556
[studies of dnp protein dissociation in the presence of norepinephrine].	calf thymus dnp dissociation was studied by sepharose 2b gel-chromatography as well as by oxyapatite ion-exchange chromatography. the degree of dissociation was estimated by protein content in the chromatography peaks. intact dnp and dnp incubated with norepinephrine were filtered simultaneously through two identical columns. in the presence of norepinephrine a partial deproteinization was observed. this effect has some specificity, namely, it was considerably lower in the presence of tyrosine, ...	1978	96558
[effect of the diet containing rendering fats on the milk yield and vitamin e content in the milk of dairy cows].	in three groups of first-calvers with 15 animals each, with an identical basal diet, we followed for six months the effect of the dob mixture additive without fat, the dob mixture with 5% of rendering-plant fat obtained mechanically and dob with 5% of rendering-plant fat after perchlorethylene extraction (0.90% perchlorethylene residuum). this additive of rendering-plant fats in concentrate mixtures as a substitute for grain in our experiment increased milk efficiency and the production of milk ...	1978	96572
terminal redundancy of "high frequency of recombination" markers of bacillus subtilis phage spo1.		1978	96587
development of visual acuity in infant monkeys (macaca nemestrina) during the early postnatal weeks.		1978	96592
clinical relevance of the liver-specific lipoprotein (lsp).		1978	96648
structural alterations of the porcine heterograft after various durations of implantation.	morphologic changes in six glutaraldehyde-fixed porcine heterografts recovered from five patients were studied with light and scanning electron microscopy. light microscopy showed minimal changes in the valves recovered after 2 months of implantation. fibrin deposits, red blood cell trapping, disruption of the valve matrix and interstitial edema were noted in heterografts 2 months and 2 years after implantation. in valves examined with scanning electron microscopy, 6 hours after implantation the ...	1978	96685
contrasting effects of living in heterosexual pairs and mixed groups on the structure of social attraction in squirrel monkeys (saimiri).	the structure of social attraction was assessed in pair- and group-living squirrel monkeys (saimiri) using paired-comparison and single-stimulus preference tests. effects of the social environment were most prominent in females. females housed with a single male showed sharply increased attraction to like-sex strangers and less pronounced increase in attraction to opposite-sex strangers, as compared to group-living females. differences between pair- and group-living males were in the same direct ...	1978	96707
circadian variations in cortisol concentrations in the plasma of female rhesus monkeys.		1978	98605
purification and some properties of ovine placental lactogen.	a method has been described for the purification of ovine placental lactogen (opl) involving the use of freshly obtained sheep foetal cotyledons. tissue was extracted with 0.1 m-ammonium bicarbonate and the supernatant fraction, adjusted to ph 7, was brought to 60% saturation with ammonium sulphate. the resulting precipitate was then subjected to a sequence of chromatographic steps using columns of sephadex g-100 and carboxymethylecellulose. during each stage of the purification, the lactogenic ...	1978	98606
observations on acute gastric dilatation in nonhuman primates.	in the years 1967-1977 we diagnosed 23 cases of acute gastric dilatation in monkeys. fourteen of these animals were macaca mulatta, five macaca fascicularis, and one each of macaca nemestrina, aotus trivirgatus, saimiri sciureus, and colobus guereza. fourteen of the animals were males, nine were females, and all were adults or subadults. mortality was 78% (18 of 23 animals). thirteen of the animals had received on anesthetic, immobilizing, or tranquilizing drug 1-2 days before developing acute g ...	1978	98666
effect of starvation on hypothalamic-pituitary-thyroid function in the rat.	total starvation in the rat for 2 days did not alter the hypothalamic content of thyrotropin-releasing hormone (trh), but did decrease both pituitary tsh content and serum tsh concentration. five days starvation resulted in a significant decrease in serum tsh and a slightly enhanced serum tsh response to exogenous trh, suggesting that the pituitary retains its sensitivity to trh. fasting for 5 days resulted in a decreased 1 and 4th, but an increased 24th thyroid 131i uptake. other starvation-ind ...	1978	98684
evidence that f' lac replicates asynchronously during the cell cycle of escherichia coli b/r.	the replication of f' lac was studied in exponentially growing cultures of e. coli b/r. the cells were pulse induced for the synthesis of beta-galactosidase and their dna pulse labelled with 3h thymidine. the cells were then separated into age classes by centrifugation through a sucrose gradient in a zonal rotor. plasmide replication was measured in each age fraction by three methods: the rate at which beta-galactosidase could be induced, the amount of label incorporated into ccc plasmid dna whi ...	1978	98704
suppression of oestrogen-induced lh surges by social subordination in talapoin monkeys.		1978	98718
the effects of sodium nitroprusside and trimethaphan camsylate on cerebral blood flow in rhesus monkeys.	hemispheric cerebral blood flow was measured in the rhesus monkey before and after infusion of the hypotensive agents sodium nitroprusside and trimethaphan camsylate. the intracarotid injections of 133xe was utilized, and flow was calculated by the "flow initial" technique. cerebral blood flow did not change significantly with the administration of trimethaphan camsylate. however, with a small reduction in blood pressure (10.6%) during the administration of sodium nitroprusside, the cerebral blo ...	1978	98729
electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey.		1978	98733
the bacterial pathogenesis of acute pelvic inflammatory disease.	to study the bacterial pathogenesis of acute pelvic inflammatory disease, peritoneal fluid was obtained by culdocentesis in 133 of 344 women with this disease. in 104 of the specimens bacteria were identified both in the gram-stained smear and culture. neisseria gonorrhoeae was isolated from the lower genital tract in over half of these women, and there were 3 patterns of bacterial recovery from peritoneal fluid: n gonorrhoeae alone (22%), n gonorrhoeae and other organisms (32%), and nongonococc ...	1978	98745
reduced hepatic bilirubin uridine diphosphate glucuronyl transferase and uridine diphosphate glucose dehydrogenase activity in the human fetus.	hepatic bilirubin uridine diphosphate glucuronyl transferase (udpg-t) activity was 0.14 and 0.22 units in two fetuses aged 17 and 22 weeks, respectively, and less than 0.1 unit in 15 fetuses, aged 8--19 weeks compared to 0.68--1.99 units in 21 normal adults. hepatic uridine diphosphate glucose dehydrogenase (udpg-d) activity in 14 fetuses, aged 8--18 weeks, ranged from 6.2--15.0 units (mean = 11.3 +/- 0.7) compared to 28.8--49.2 units (mean = 39.6 +/- 2.5) in eight normal adults (p less than 0.0 ...	1978	98749
location of the genes for human heavy chain immunoglobulin to chromosome 6.	immunoglobulin synthesis was examined in 31 man-mouse hybrid clones produced by fusing rag mouse cells with human lymphoid cells. cells were grown in serum-free medium containing [(14)c]leucine and a (14)c-labeled amino acid mixture. spent medium was dialyzed, concentrated, and subjected to radioimmunoelectrophoresis. eighteen clones were found to produce material that gave a radiolabeled precipitin line with anti-human igg (gamma-chain specific). production of material which was indistinguishab ...	1978	98768
contraction of detergent-treated smooth muscle.	after exposure of segments of rabbit taenia coli to the nonionic detergent triton x-100, tension could be induced by increasing the [ca2+] in the micromolar range. in the presence of a saturating [ca2+], this preparation developed nearly 100% of the control tetanus tension recorded from the intact muscle prior to the detergent treatment. in addition, tension could be induced by increasing the [mg2+], in the virtual absence of ca2+. mg2+ seems to inhibit the ca2+-induced tension in a predominantl ...	1978	98770
plasma membrane vesiculation: a cellular response to injury.	the shedding of plasma membrane vesicles has been shown to result from exposure of monolayer cell cultures to formaldehyde and other sulfhydryl blocking agents. incubation of cells in concentrations of these agents as low as 5 to 10 mm for intervals as brief as fifteen minutes is effective (scott, 1976). plasma membrane vesiculation has been shown to be an energy-dependent process that requires ca++ and physiological temperature. following plasma membrane vesiculation, cell monolayers appear int ...	1978	98904
quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia.	changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ...	1978	98907
[some aspects relating to the aflatoxin generation during the self-heating of cereals].	in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ...	1978	98933
age-associated changes in the blood picture of the goat.		1978	98936
the effect of complement depletion on bacterial lipopolysaccharide (lps)-induced hemodynamic and hematologic changes in the rhesus monkey.	lipopolysaccharide (lps) isolated from salmonella minnesota r595 or from escherichia coli 0111:b4 induces hypotension in rhesus monkeys with normal complement levels. this hypotension is accompanied by decreased total peripheral resistance. the depletion of c3 and terminal complement components by prior intraperitoneal administration of the anticomplementary protein cobra factor did not alter the hemodynamic changes which occur following the rapid injection of 5 mg/kg of r595 lps, the infusion o ...	1978	99042
catabolism and protein binding of tc-99m pyridoxylideneglutamate.	various tc-99m-labeled compounds have been suggested as replacements for [i-131] rose bengal for imaging of the hepatobiliary system. among such compounds are schiff's bases, which are tin-free tc-chelates easily prepared by 30-min autoclaving of an equimolar mixture of pyridoxal and an amino acid at ph 8.5. we have compared the properties of several schiff's bases, including tc-99m pyridoxylideneglutamate (tc pyg) with [i-131] rose bengal. under conditions described, tc-pyg can be prepared free ...	1978	99499
nature's infant nutrition. breast feeding: a means of imparting immunity?		1978	99622
the effects of foveal prestriate and inferotemporal lesions on matching to sample behaviour in monkeys.		1978	99683
behavioral measurement measurements of excitability changes in reward sites in the dog: a frequency dependent effect.		1978	99757
morphology of freeze-etched treponema refringens (nichols).	the freeze-etch technique was used to study the morphology of treponema refringens (nichols). there is a single band of cytoplasmic fibrils which follows a path in the form of a right-handed helix with a periodicity of 1500 nm around the body of the treponeme just below the cytoplasmic membrane. there are two major fracture planes, one located in the interior of the outer envelope and the second in the interior of the cytoplasmic membrane. the "blebs" or "surface protuberances", which are quite ...	1978	100069
ultraviolet light-induction and photoreactivation of thymine dimers in a cyanobacterium, anacystis nidulans.	partially photoreactivable mutant of anacystis nidulans demonstrates partial photorepair of thymine dimers. the wild type which is completely photoreactivable at the conditions studied shows higher level of thymine dimer photolysis.	1978	100072
[delayed implantation and early developmental defects in the mouse caused by pcb: 2,2'-dichlorobiphenyl (author's transl)].	pregnant mice administered per os during the days 1--3 (plug day = day 0) post conception (p.c.) with 375 mg 2,2'-dichlorobiphenyl/kilograms/day revealed on day 18 p.c. increased number of resorptions and doses up from 500 milligrams/kilograms/day led to a substantial retardation of the prenatal development. based on the investigations during the early development it is concluded, that retardation of the fetus is caused by a delayed implantation. it is assumed, that increased resorption is due t ...	1978	100080
trifluridine in resistant human herpetic keratitis.	patients with active dendritic herpetic keratitis that was unresponsive to topical idoxuridine or vidarabine therapy were treated topically with a 1% solution of trifluridine. the dendritic ulcers healed in an average time of 6.1 days. all patients tolerated the drug well except for one patient in whom a reversible crystalline epithelial keratitis developed.	1978	100084
cooperative binding of mn2+ and non-cooperative binding of mg2+ to beta-galactosidase (e. coli).		1978	100107
[picosecond energy transfer between the spectral forms of pigments from the reaction center of rhodospirillum rubrum].	absorption changes of reaction centers from rhodospirillum rubrum at 748, 796 and 870 nm induced by 532 and 870 nm picosecond light pulses were investigated with a picosecond spectrometer. kinetics of absorption changes at 748 and 796 had an additional bleaching when induced by the 532 nm pulse, in comparison with those at 870 nm. the additional bleaching was interpreted as a result of the excitation energy transfer via spectral forms of pigments of reaction centers. the experimental results fit ...	1978	100143
[origin of a mitogrenic factor for cultivated macrophages (imf: inflammatory mitogenic factor) found in exudates of non-specific acute inflammation].	the mitogenic activity of inflammatory exudate obtained from irradiated rats is reduced. after transfer of bone marrow syngeneic cells into irradiated rats this mitogenic activity is further decreased, while after transfer of thymic cells it is increased. it is postulated that the mitogenic activity of inflammatory exudate could be related to thymic cells and that t lymphocytes may be involved in non specific-inflammatory reactions.	1978	100246
clinical and pathologic features of various drug-related problems in the control of swine dysentery.		1978	101498
detergent-resistant variants of bacillus subtilis with reduced cell diameter.	variants of bacillus subtilis resistant to the detergent triton x-100 may exhibit: (i) normal cell morphology, (ii) reduced cell diameter, or (iii) helical cell shape. one variant of type ii was studied in some detail. triton resistance, cell diameter reduction, and poor sporulation all may have resulted from a single mutation. high concentrations of triton caused rapid lysis of wild-type cells. b. subtilis adapted to low triton concentrations such that, upon subsequent exposure to higher concen ...	1978	101507
occurrence of squalene and sterols in cellulomonas dehydrogenans (arnaudi 1942) comb. nov. hester 1971.	the neutral lipid fraction of the photochromogenic, coryneform bacterium cellulomonas dehydrogenans (arnaudi 1942) comb. nov. contains the sterol precursor squalene and at least two sterols, cholesterol and beta-sitosterol. the compounds were characterized by mass spectrometry and combination gas-liquid chromatography--mass spectrometry. de novo sterol biosynthetic ability was shown from incorporation of 14c from d-[u-14c]glucose into squalene and the sterol fraction. the squalene concentration ...	1978	101527
detection of intermediates in protein folding of carbonic anhydrase with fluorescence emission and polarization.	the three-dimensional structure of carbonic anhydrase is a result of specific folding of the protein chain to form a compact, globular molecule. fluorescence measurements on the nature of the rate-limiting steps in folding from the random coil to the native structure show that each step involves an actual folding reaction of the protein chain. emission intensity and polarization of the intrinsic fluorescence due to tryptophan residues reach a maximum during the early period of the folding proces ...	1978	101537
studies of the lymphoreticular system in the pathogenesis of scrapie: the role of spleen and thymus.		1978	101558
incorporation of amino acids by isolated submitochondrial fractions of lactating goat mammary gland in vitro.	incorporation of amino acids by mitochondria and its subfractions from mammary gland of the goat during lactation was studied in vitro. assessment of distribution of radioactivity incorporated by intact mitochondria into its subfractions revealed maximum specific activity in the inner membrane. during lactation the inner membrane of mitochondria exhibited further stimulation in such incorporation. matrix was the next active fraction whereas outer membrane and peripheral space had negligible radi ...	1978	101564
serologic typing of rickettsiae of the spotted fever group by microimmunofluorescence.		1978	101593
[salmonellosis].		1978	101617
[exocrine gland activities and the kinin system].		1978	101694
studies on virus-inhibiting substances of bacterial origin. iv. antiviral substances extractable from streptococcus faecalis: its in vivo effect.		1978	101714
the effect of dinitrochlorobenzene (dncb) on dimethylbenzathracene (dmba) carcinogenesis on hamster buccal pouch.	dncb is an antigen that stimulates the cell-mediated response in a sensitized host. the purpose of this study was to define the effect dncb would have on a standard model system for oral carcinogenesis, theorizing that tumorgenesis would be delayed or inhibited. fifty-six syrian hamsters were divided into four groups. in group a (dncb/dmba), the right buccal pouch of twenty animals was treated with 2% dncb in orabase, twice a week, and 0.5% dmba, three times a week, for 10 weeks. in group b, twe ...	1978	101932
[microbiological characteristics of intestinal dysbacteriosis in acute leukemia].		1978	101983
oxygen requirement for prostaglandin biosynthesis.	the formation of prostaglandins by vesicular gland cyclooxygenase can be regulated by o2 concentrations below 30 micron (20 mm hg) with an apparent km value of about 5 micron. this result suggests that most mammalian tissues might be expected normally to have sufficient o2 for some synthesis, and that only occasionally, would the level of oxygen available within some tissues become marginally inadequate to sustain a high rate of prostaglandin biosynthesis.	1978	102002
effect of arachidonic acid on some inhibitors of the human platelet release reaction.		1978	103548
immunological heterogeneity of haemophilia b: a multicentre study of 98 kindreds.	an electroimmunoassay with a precipitating rabbit anti-human factor ix antiserum and an inhibitor neutralization assay with a non-precipitating homologous antibody were used to measure factor ix antigen (ix:ag) in 117 patients from 98 kindreds with haemophilia b; and to investigate in a mixed population the incidence of different immunological types of the disease. although the two assays showed an excellent correlation, the electroimmunoassay was selected for its simplicity as a criterion for c ...	1978	103564
effect of cobalt-60 radiation on response to endodontic therapy in monkeys.	response of teeth that had received therapeutic doses of cobalt-60 radiation to endodontic therapy were investigated in three monkeys. the results indicated no appreciable effect of the irradiation on the response to root canal treatment aside from reduction in osteoblastic activity.	1978	103612
[epileptogenic action of intra-amygdaloid injection of kainic acid].	intra-amygdaloid unilateral application of low doses of kainic acid rapidly elicits, in both chronic and acute conditions, secondarily generalized convulsive seizures which often culminate in fatal true status epilepticus unless appropriate anti-epileptic drugs are provided. spontaneous recurrent seizures are observed for several hours starting approximately 10 min. after the application of kainic acid. in addition to the primary degeneration in the amygdaloid complex, a secondary cell loss is s ...	1978	103652
focal penicillin epilepsy in an isolated cerebral hemisphere.		1978	103744