Publications

pattern of malformations in the children of women treated with carbamazepine during pregnancy.	in an attempt to determine whether and to what extent carbamazepine is teratogenic, we evaluated eight children whom we identified retrospectively as having had prenatal exposure to carbamazepine alone or in combination with a variety of anticonvulsants other than phenytoin. in addition, in a prospective study, we documented the outcome of the pregnancies of 72 women who contacted us early in pregnancy because they were concerned about the potential teratogenicity of carbamazepine. a pattern of ...	2009	2725616
[diagnosis and treatment of liver injuries and their sequelae].	the authors studied 222 cases of closed and open injuries to the liver and, in addition, had 5 patients who were treated for sequelae of injury (hemobilia, abscesses, biliary fistula of the liver). the diagnosis of open injuries to the liver is established without great difficulties; laparocentesis and laparoscopy are indicated in closed injury. the volume of the operation is determined by the character of the damage: closure of the hepatic wound proves sufficient in most patients; surgical debr ...	2009	2704167
[morphology of the palatine tonsil lymphocytes in chronic tonsillitis using data of electron microscopic radioautography].	electron-microscopic and electron-radioautographic examinations of the palatine tonsil lymphocytes in 20 patients with chronic decompensated tonsillitis, aged 21-50, have revealed the proliferation of poorly differentiated t- and b-lymphocyte pools in the lymphoid tissue of the tonsils; these processes manifest by an intensive 3h-thymidine incorporation into the minor lymphocytes of different types. a high level of the rna radioactive precursor incorporation in b-lymphocytes indicates a constant ...	2009	2712729
challenges to conducting research with children with cancer.		2009	2755865
isolation and structure of two novel 6-kda dimeric peptides from the corpora cardiaca of the insect locusta migratoria. molecular mass determination by mass spectrometry.	we have isolated two major 6-kda peptides from extracts of corpora cardiaca of adult females of locusta migratoria. these peptides have been characterized by peptide sequencing and liquid secondary-ion mass spectrometry. they are structurally related dimers, one (6278.5 da) being a homodimer (a-a chains), the other (6280.5 da) being a heterodimer (a-b chains). a 60% similarity exists between the a and b chains. both peptides have been chemically synthesized and the synthetic compounds appeared t ...	2009	2731552
lumboperitoneal shunt combined with myelotomy for treatment of syringohydromyelia.	this study was undertaken to investigate whether a direct communication between the fourth ventricle and the syrinx exists in the majority of patients with syringohydromelia and whether intraspinal pressure plays a role in the pathogenesis of this disorder. a series of 13 patients with syringohydromyelia delineated by magnetic resonance (mr) imaging was reviewed, and the intracranial pressure (icp) and lumbar spinal pressure (lsp) were recorded concomitantly in three patients. lumboperitoneal sh ...	2009	2709113
myopathy and accumulation of amiodarone.		2009	2725579
flexible oesophagogastroscopy in otolaryngology.	we describe a technique of flexible endoscopy of the upper aerodigestive tract which provides excellent visualization for diagnostic and therapeutic purposes in ent practice. with the present day need to reduce costs it is helpful to reduce inpatient workload and perform procedures as day cases where appropriate. the previous criticisms of flexible oesophagoscopy by ent surgeons are unfounded and indeed there are situations where flexible endoscopy is superior to rigid examination. we would reco ...	2009	2715694
acute pseudobulbar palsy due to bilateral focal cortical damage: the opercular syndrome of foix-chavany-marie.	two children are described who suddenly developed an encephalitic illness with intractable bilateral facial seizures. the seizures subsided over several days, but the children were left with the signs of pseudobulbar palsy and are unable to speak or swallow effectively. bilateral destructive lesions in the opercular regions evolved on computed tomographic scans. both children were treated with acyclovir relatively early in the illness, and cerebrospinal fluid and serum antibodies support the dia ...	2009	2715610
[new construction principles for silicoater-cast maxillary prosthesis].	a problem often seen in the dentist's practice is the relining of a removable cr-co-prosthesis in the reduced maxillary arch. for this reason we have developed a prosthesis that has its base completely surrounded with acrylic. this modification is nearly as stable as a total cr-co-prothesis. the results on 15 patients restored with this new prosthesis were very positive.	2009	2700856
apolipoprotein b metabolism in homozygous familial hypercholesterolemia.	this report describes the metabolism of apolipoprotein b-containing lipoproteins in seven familial hypercholesterolemic (fh) homozygotes and compares the results to the values obtained from five healthy control subjects. the concentration, composition, and metabolism of large, triglyceride-rich very low density lipoproteins (vldl1, sf 60-400) were the same in the control and fh groups, indicating that this component of the vldl delipidation cascade ws unaffected by the absence of receptors. in c ...	2009	2715722
managerial boredom.		2009	2703901
cortisol induction of metallothionein in primary culture of rainbow trout hepatocytes.	in the present experiment, metabolically active primary cultures of rainbow trout hepatocytes were utilized to study the inducibility of metallothionein after cortisol treatment. glucocorticoid induction of metallothionein has previously only been demonstrated in mammalian systems. we now demonstrate the inducibility of rainbow trout metallothionein by cortisol treatment of primary hepatocytes. a 90% elevation above control levels was achieved within 8 days of treatment. zinc treatment was perfo ...	2009	2708457
[clinical results of thermoradiotherapy of locally advanced and recurrent breast cancers--comparison of results with radiotherapy alone].	from august 1979 through january 1988, 23 breast cancer patients with 25 tumors supposed to be refractory to conventional treatment were treated by thermoradiotherapy. of the 25 tumors, 10 were locally advanced primary tumors [group 1], 4 locally advanced recurrent tumors after operation more than 5 cm in maximum diameter [group 2], and 11 locally recurrent tumors after radiotherapy [group 3]. the present study was not a formal randomised-trial, but a historical-controlled study. the results wer ...	2009	2755796
[preparation and in vitro study of suppositories containing no-spa. i. significance of choosing the basic substance. determination of physical parameters of suppositories].		2009	2711838
lung parasitoses.		2009	2676037
[aortocoronary bypass. development of technics and indications over a 10-year period].	during the 1973-1983 period considerable changes have taken place in the techniques and indications of coronary bypass. in a homogeneous series of 3095 patients operated upon by the same group, changes in techniques have been: the introduction in routine coronary bypass of the membrane oxygenator which provides optimal biological conditions and the prolonged circulatory assistance so necessary to high risk patients, and the application to coronary bypass of microsurgical techniques enabling surg ...	2009	2937040
new hydrogen-bond potentials for use in determining energetically favorable binding sites on molecules of known structure.	an empirical energy function designed to calculate the interaction energy of a chemical probe group, such as a carbonyl oxygen or an amine nitrogen atom, with a target molecule has been developed. this function is used to determine the sites where ligands, such as drugs, may bind to a chosen target molecule which may be a protein, a nucleic acid, a polysaccharide, or a small organic molecule. the energy function is composed of a lennard-jones, an electrostatic and a hydrogen-bonding term. the la ...	2009	2709375
airway responsiveness in infancy.		2009	2889415
[direct endolymphatic administration of antitubercular drugs in patients with inflammatory diseases of the urogenital organs].	direct endolymphatic administration of broad-spectrum antibiotics was used in treatment of approximately 21 patients with complicated urogenital tuberculosis. the duration of the endolymphatic therapy ranged from 3 to 13 days. in the patients treated with endolymphatic administration of the antibiotics the effects were favourable. the use of the procedure were shown expedient because marked lesions in the urinary tracts, frequent chronic renal failure and the microbial flora resistance to the dr ...	2009	2704711
determination of elastase activity by reversed-phase high-performance liquid chromatography.	the action of elastase on elastin was measured by high-performance liquid chromatography with on-line post-column derivatization. after alkaline hydrolysis, a 20-ml sample was injected into a ods-2 gel column. an elastin-specific dipeptide, val-pro, and the internal standard, gly-leu, were eluted by a linear gradient of 0 to 10% of 1-propanol in 50 mm heptafluorobutyrate (ph 3) at a flow-rate of 1 ml/min. the eluent was reacted with fluorescamine, and the fluorescent products were measured. rete ...	2009	2708474
evaluation of some prognostic factors in small squamous cell carcinoma of the mobile tongue: a multicenter study in sweden.	in a retrospective study of 58 patients from all over sweden, treated for small squamous cell carcinoma of the mobile tongue (t1n0m0), different prognostic factors were evaluated. a partial glossectomy was performed as primary treatment in all patients. the cancer recurred in 28 (38%) of 58 patients. one of 7 patients with only local recurrence, and 9 of 14 with recurrence in the neck died of their disease. the relative survival rate was 77%. of the prognostic factors tested, tumor thickness was ...	2009	2681065
a case of acute psychosis in temporal association with theophylline toxicity.		2009	2708558
reduced renal clearance of oxypurinol during a 400 calorie protein-free diet.	a decrease in dietary protein intake lowers the clearance of a number of substances excreted principally by the kidney including uric acid and oxypurinol, the major metabolite of allopurinol. we studied the kinetics of uric acid and oxypurinol in seven healthy volunteers on a normal protein diet (2600 calories; 100 g protein) followed by a 400 calorie, protein-free diet. a 600 mg dose of allopurinol was given orally after 6 days of the normal protein diet and again after 2 days of the 400 calori ...	2009	2708550
[a new enamel-dentin adhesive. method of use].	this article reviews instructions for the use of a new enamel-dentin bonding agent, scotchbond 2 from the 3m company. precise recommendations relative to cervical lesions are presented and discussed.	2009	2698400
long-term outcomes of an arthritis self-management study: effects of reinforcement efforts.	an underlying assumption of self-care interventions is that they are most effective when reinforced. to test this assumption, 8 months after baseline, 589 subjects who had taken a 6-week arthritis self-management course (asmc) were randomized to (1) receive a bi-monthly arthritis newsletter, (2) attend a new 6-week arthritis reinforcement course (arc) or (3) receive no reinforcement. between 8 and 20 months there were no significant differences among the three randomized groups. the results were ...	2009	2665110
cross-reactive binding patterns of monoclonal antibodies to dna are often caused by dna/anti-dna immune complexes.	recently, the role of antibodies to dna in the pathogenesis of systemic lupus erythematosus (sle) has been reevaluated, since observed cross-reactive binding of anti-dna to tissue-related antigens might substantially contribute to the inflammatory process of the disease. evidence of this cross-reactivity has, in part, been obtained from studies with monoclonal anti-dna. however, we now report that the presence of dna/anti-dna immune complexes in monoclonal antibody preparations may be the cause ...	2009	2781137
introduction to immunocytochemistry.	immunocytochemistry has opened a new era in research and diagnosis. the development of immunocytochemical methods has made it possible to identify in situ normal and pathological tissue constituents, which it has not been possible to detect using ordinary histological methods. however, immunocytochemical techniques involve several pitfalls, which without proper control protocols can easily lead to incorrect findings. when interpreting the results obtained, account must always be taken of the mor ...	2009	2664772
[amborum special f and asfo--2 glucocorticoid-containing herbal remedies].	amborum special f and asfo are two names of a herbal remedy which is adulterated with the glucocorticoid betamethasone. patients with asthma, rheumatic and chronic diseases import the drug direct from burbank, california, usa. its impressive antiasthmatic effect is reported in two patients. while under therapy the first patient developed cushing's syndrome and the second showed suppression of adrenal cortisol production. the manufacturer, who claims that the drug contains no "western medicine" a ...	2009	2762789
treatment of hematogenous pyogenic vertebral osteomyelitis with anterior debridement and primary bone grafting.	from 1971 to 1984 at the university of rochester medical center, 23 adult patients underwent surgical treatment via an anterior approach for pyogenic vertebral osteomyelitis. data from 21 patients with greater than 2-year follow-up is presented in this report. surgical debridement via an anterior approach was performed in all 21 patients. bone grafting with iliac crest or rib strut was done in 19 patients. clinical follow-up averaged 4 years, with a range of 2 years to 9 years, 9 months. no pati ...	2009	2652335
[history of the organization of emergency services in st. petersburg].		2009	2652330
[ear diseases--potentials and limitations of radiology].	the possibilities and limitations of conventional plain x-ray films, angiography, pluridirectional tomography, high-resolving ct (hr-ct) and magnetic resonance tomography (mrt) are described in general and then demonstrated in greater detail on the basis of characteristic findings in otological diseases. hr-ct is definitely superior to pluridirectional tomography within the general framework of diagnostic technique that goes beyond the initial findings. mrt is of only limited diagnostic value de ...	2009	2652270
bone mass, muscle function and fracture of the proximal femur.	the epidemiology and pathogenesis of hip fractures are reviewed. there is evidence that physical inactivity and concomitant muscle weakness are important determinants of the risk of hip fracture.	2009	2679947
[a new inflammatory muscular disease: inclusion-body myositis].		2009	2835126
success of etched-metal bonded retainers with nonrigid connections: a clinical study.	the use of etched-metal bonded retainers in combination with conventional fixed retainers has been described in the literature. this design creates several potential problems that can be overcome by the use of an etched-metal bonded retainer with a nonrigid connector as described in this article. also presented are the preliminary results of a clinical study of 25 restorations that had been in place 13 to 45 months (average 22 months). the preliminary results are encouraging. no failures have be ...	2009	2681695
the sin of pride: research in obstetrics and gynecology.		2009	2653038
fact and fashion: changing practices in child psychiatry.		2009	2681776
the perils of pertussis.	this article examines the perils of the contagious disease pertussis, prevalent among infants around the country. signs and symptoms of the disease are discussed, along with the current and future means of its diagnosis. pertussis immunization, legal aspects, side effects, and schedule are discussed. current medical treatment and nursing management are also presented. finally, a care plan for the infant with pertussis utilizing nursing diagnosis is introduced.	2009	2668497
biblical leprosy: a comedy of errors.		2009	2681774
endoscopic sclerotherapy for esophago-gastric varices: a critical reappraisal.	amongst the many non-surgical techniques for the treatment of variceal bleeding, endoscopic sclerotherapy (est) has shown great promise. est can successfully obliterate esophageal varices and prevent variceal rebleeding. it is also very effective in the control of active bleeding from esophageal varices. the technique of est is simple and can be carried out with a conventional, forward viewing, flexible endoscope and a teflon injector. weekly intravariceal injections of an aqueous sclerosant are ...	2009	2669716
growth factors, oncogenes and anti-oncogenes in cancer.		2009	2665243
intestinal autointoxication: a medical leitmotif.	the idea that putrefaction of the stools causes disease, i.e., intestinal autointoxication, originated with physicians in ancient egypt. they believed that a putrefactive principle associated with feces was absorbed in to the general circulation, where it acted to produce fever and pus. this description of the materia peccans represented the earliest forerunner of our present notion of endotoxin and its effect. the ancient greeks extended the concept of putrefaction to involve not only the resid ...	2009	2668399
[prognosis in synchronous liver metastasis from colorectal cancer. a multicenter study of patients with cancer of the rectum and cancer of the rectosigmoid colon].	a prospective investigation of 188 patients with cancer of the rectum and rectosigmoid colon with synchronous liver metastases is described. the mean survival time for 183 patients who did not receive any treatment for the liver metastases was six months and only one survived for longer than 37 months. after extirpation of the primary tumour, the most significant prognostic factors were etrahepatic metastases, enlarged liver on account of metastases and more than three liver metastases. serum ba ...	2009	2660370
gay and lesbian youth, emergent identities, and cultural scenes at home and abroad.	this introduction opens up the field of studies of gay and lesbian adolescents, both with regard to past and present studies in the research literature, and by allusion to the new studies collected in this issue. historical and crosscultural elements of the context of the "coming out" process are discussed. four preconceptions of gay youth are critically examined, regarding their heterosexuality, inversion, stigma, and heterogeneity. the anthropological construct of life crisis "rites of passage ...	2009	2668402
hyperosmolar coma: cellular dehydration and the serum sodium concentration.		2009	2655518
osteoporosis: prevention and treatment.		2009	2644114
links between clinical and experimental neuropsychology.	the goals of both experimental and clinical neuropsychology involve qualitative analyses of the behavioral sequelae of brain damage in humans. both of these subdisciplines attempt to delineate and clarify perceptual, cognitive, linguistic, affective, and other changes in individuals with neurological disease--particularly as these disorders contribute to our understanding of normal brain function and its modification by pathology. thus, an interest in brain-behavior relations is coupled with dia ...	2009	2668327
response of solid tumors to chemotherapy monitored by in vivo 31p nuclear magnetic resonance spectroscopy: a review.	in vivo 31p nuclear magnetic resonance (mr) spectroscopy has shown great promise as a tool for cancer research and the clinical management of solid tumors. it is now possible in some cases to integrate mr spectroscopy with routine mr imaging of the cancer patient, so that tissue identified as tumor on an mr image can be examined biochemically and monitored following treatment. alterations have been observed in the phosphorus mr spectra of patient tumors after treatment, but the causes and conseq ...	2009	2663140
[the role of the trs-glucotest apparatus in self-monitoring by patients with diabetes mellitus].	successful treatment of diabetes mellitus requires a reliable control of glycaemia where self-monitoring with reflectometer plays a significant role. trs-glucotest reflectometer (trs, zagreb), the result of our experts' efforts, makes it possible for diabetic patients to perform self-monitoring. according to our research trs-glucotest reflectometer shows lower blood glucose levels for more than 20%, especially in 3.8-11.5 mmol/l range of glucose concentration, that is in the range most often exp ...	2009	2633013
a control systems framework for understanding normal and abnormal posture.	this paper presents a brief overview of a control systems framework for understanding normal and abnormal posture, with a special emphasis on postural control during arm movements. the need for meaningful and valid definitions of postural output is discussed. a distinction is drawn between the joint posture and balance outputs of the system. the roles of commands and perturbing inputs in controlling and disturbing joint posture and balance are described. the effects of initial conditions on comm ...	2009	2655455
intraperitoneal treatment of capd peritonitis with ciprofloxacin.		2009	2613610
infertility clinic at consolata hospital, nkubu kenya (1987).	data regarding 266 cases of couple infertility were reviewed in the infertility clinic of consolata hospital, nkubu, meru, between january and december 1987. of these, 132 were cases of primary infertility and 134 of secondary infertility. 218 women with primary and secondary infertility were investigated with tubal insufflation with the result that 163 (74.8%) presented tubal occlusion. besides more than 68% of primary infertility cases had a positive smear for gonorrhoea.	2009	2606025
left atrial catheter complications.		2009	3724223
[amputation black on white].		2009	2915836
rehabilitation of atrophied muscle in the rheumatoid arthritic hand: a comparison of two methods of electrical stimulation.	this study compares the effectiveness of two therapeutic electrotherapies which result in plastic adaptation in the atrophied muscle of rheumatoid arthritic hands. the natural discharge pattern of a fatigue-resistant motor unit (eutrophic electrotherapy) was more effective than a uniform 10 hz electrotherapy. it was concluded that uniform 10 hz electrotherapy ignored the information carried in the motor unit action potential spike train, which was the signal inducing rapid and behaviourally effe ...	2009	2794708
ewing's sarcoma of metacarpal. a case report and review of literature.	the radiological features of a rare case of ewing's sarcoma of right fourth metacarpal in a twenty-five years young male are described. an up date review of literature is also presented.	2009	2698379
predictive value of a short dietary questionnaire for changes in serum lipids in high-risk utah families.	dietary questionnaires and serum cholesterol, triglycerides, and high-density lipoprotein (hdl) cholesterol determinations were completed for 1239 subjects aged greater than or equal to 20 at each of two separate screenings. the mean time between screenings was 2.5 y. after correcting for potential confounding variables, reduction of a measure of dietary cholesterol and saturated fatty acids assessed by two simple questions was a significant independent predictor of reduction in total cholestero ...	2009	2756916
the importance of previous convictions in assessing criminal motivation--the need for detail.	full details of an offender's previous convictions are not customarily available to those who have to try to predict the possibility of future dangerous behaviour. it is suggested that such information might enhance the quality of prediction; some illustrations are offered in support of this contention.	2009	2747471
low nanogram detection of nucleotides using fast atom bombardment-mass spectrometry.	the effect of trimethylsilyl (tms) derivatization on detection limits of mononucleotides in fast atom bombardment-mass spectrometry (fab-ms) was examined. fab-ms methods were developed to optimize sensitivity using adenosine 5'-monophosphate as a model compound and then applied to reference standards of two clinically important nucleotides: tricyclic nucleoside-5'-monophosphate (tcnmp) and 5-fluoro-2'-deoxyuridine-5'-monophosphate (fdump). the detection limit for the tms derivative of tcnmp was ...	2009	2729562
[microcomputer-assisted system for photographing the movements of biological valve prostheses].	the aim of the study was to develop a clinically usable system of photographic imaging of the movements of biological valve transplants and of evaluating temporal and spatial relationships. the system has been established by means of a microcomputer and associated peripheral electronic equipment so that there is no need to use a high-speed camera. functioning of the system was verified by testing 37 aortal valve allotransplants and the björk shiley mechanical valve prosthesis.	2009	2758334
[our experience in treating peritonitis following cesarean section].	fourteen parturients were admitted and treated in the ward of emergency operative gynecology of the "n. i. pirogov" rnpismp for the period of 1980-1986 in connection with peritonitis after caesarean section. four out of 14 parturients died. the clinical course of peritonitis after caesarean section is changed considerably under present conditions. nontypical symptoms of its course create considerable difficulties in diagnosis and lead to late therapeutic measures, which worsen the outcome of tre ...	2009	2764246
[determining the diagnosis--tumor of the kidney pelvis--using sonography].	the advantages and deficiencies of diagnostic imaging procedures especially of ultrasonography in the diagnostics of solid masses in the renal collecting system are presented. the intravenous urography is important as basic examination, but ultrasonography is valuable for additional information especially in the non-functioning kidney. a tumor could identified in the renal collecting system if its size is greater than 10 mm.	2009	2694680
pancreas transplantation.		2009	2659253
[an operative case of multiple endocrine neoplasia type 1 (men type 1) with insulinoma].		2009	2906375
hepatic extraction of morphine is impaired in cirrhosis.	using hepatic vein catheterization this study has provided the first direct measurement of morphine hepatic extraction in 8 controls and 8 cirrhotics. the extraction ratio was 0.52 in the control group and was reduced by 25% in the cirrhotics. this reduction is due to impaired enzyme capacity rather than reduced blood flow. the effect of cirrhosis is less than that reported in similar studies of high clearance oxidized drugs and this lends support to the concept that glucuronidation may be relat ...	2009	2753069
development and degeneration of retina in rds mutant mice: altered disc shedding pattern in the heterozygotes and its relation to ocular pigmentation.	in the heterozygous mutant (rds/+) mice, receptor outer segments (ros) are irregular in form and are shed as abnormally large phagosomes. in the albino rds/+ mice, peak frequency of pigment epithelial (rpe) phagosomes is higher than normal and is recorded near the end of the light period, instead of at the time of light onset as in the normal (+/+) albino mice. in pigmented mice of both genotypes, the maximum numbers of phagosomes in the rpe remain lower than in the albinos. in pigmented +/+ mic ...	2009	2612198
development and degeneration of retina in rds mutant mice: altered disc shedding pattern in the heterozygotes and its relation to ocular pigmentation.	in the heterozygous mutant (rds/+) mice, receptor outer segments (ros) are irregular in form and are shed as abnormally large phagosomes. in the albino rds/+ mice, peak frequency of pigment epithelial (rpe) phagosomes is higher than normal and is recorded near the end of the light period, instead of at the time of light onset as in the normal (+/+) albino mice. in pigmented mice of both genotypes, the maximum numbers of phagosomes in the rpe remain lower than in the albinos. in pigmented +/+ mic ...	2009	2612198
survey of preclinical medical students: declining interest in becoming a physician.		2009	2761657
multiple injuries: coma and thoracic injury.		2009	2812401
multiple injuries: coma and thoracic injury.		2009	2812401
[clinico-immunological changes in patients with chronic pancreatitis and their correction during the treatment].	the time course of quantitative and functional parameters of humoral and cellular immunity, autosensitization to pancreatic tissue was studied in 200 patients with chronic pancreatitis. it was shown that different clinical types of the disease were characterized by different types of immune shifts. correlation was found between clinical and immunological indices. immunosuppressive influence of protease inhibitors in chronic pancreatitis was shown. incorporation of the immunomodulator levamisole ...	2009	2786262
role of technetium-99m phosphonate bone and indium-111 leukocyte scanning for detecting the infected hip prosthesis.		2009	2738681
[aerosol therapy (3). the ultrasonic nebulizer].		2009	2727484
the socioeconomic problems of chronic renal failure: what can we do about them?		2009	2805695
malignant hyperthermia. potential crisis in patient care.		2009	2673033
catheterization of umbilical vessels in newborn infants.		2009	4921383
isopropanol ingestion: case report with pharmacokinetic analysis.	an unusual case of acute isopropanol overdose which occurred within the confines of the emergency department is reported. serial serum concentrations of isopropanol and its metabolite acetone were followed for 43 hours. pharmacokinetic analysis is presented, as well as a brief literature review of diagnosis and management. cns toxicity was related mainly to isopropanol concentrations. the calculated half-life of isopropanol was 7.3 hours. because of the pharmacokinetic profile of isopropanol, ma ...	2009	2712894
the significance and scope of reproductive tract infections among third world women.	due to biomedical, behavioral and societal factors, reproductive tract infections are widespread in the third world. without early diagnosis and accurate therapy, their complications severely compromise women's health, fertility and productivity; infant health and survival; and the effectiveness of family planning programs. clinicians and public health planners can address these treatable syndromes through research and services in socially acceptable settings including family planning, prenatal ...	2009	2686703
the trigeminal (v), an oft-neglected nerve.	corneal denervation is one of the most serious insults that can occur to an eye; disease symptoms can be suppressed, and epithelial breakdown is likely to occur. in the cases presented, failure to test corneal sensation delayed diagnosis and endangered the cornea. conditions affecting the trigeminal sensory pathway, including those causing a pain-anesthesia paradox, are described. corneal sensation must be tested in all instances of suspicious head pain or paresthesia, head trauma, cranial nerve ...	2009	2774430
granule-mediated cytolysis of target cells.		2009	2644070
any more cordials to the drooping spirit? professional ethics, 1847-1989.		2009	2636862
regional pain syndrome.		2009	2790410
dna methylation.	the dna of escherichia coli contains 19,120 6-methyladenines and 12,045 5-methylcytosines in addition to the four regular bases, and these are formed by the postreplicative action of three dna methyltransferases. the majority of the methylated bases are formed by the dam and dcmmethyltransferases encoded by the dam (dna adenine methyltransferase) and dcm (dna cytosine methyltransferase) genes. although not essential, dam methylation is important for strand discrimination during repair of replica ...	2009	26443769
a case of o1 vibrio cholera bacteremia and primary peritonitis in a patient with liver cirrhosis.	vibrio cholerae are gram-negative bacteria that are differentiated into o1/o139 and non-o1/non-o139 serogroups depending on their ability to agglutinate with specific antiserum. in contrast to non-o1/non-0139 vibrio cholerae, which are more prone to invade the bloodstream, vibrio cholerae o1 is rarely the cause of bacteremia. we report a case of o1 vibrio cholera bacteremia and primary peritonitis in a patient with liver cirrhosis. the literature on the subject is also reviewed.	2009	27990208
characterization of vibrio cholerae from deep ground water in a cholera endemic area in central india.	a total of 8 out of 11 deep ground water samples collected from different villages in central india were found contaminated with vibrio cholerae non o1, non o139. in a multiplex pcr, isolates were found positive for ompw gene but negative for ctxab and rfbo1 genes. however, isolates from two places were positive for tcp and zot genes, indicating their intestinal colonization and toxigenic potential. antibiotic susceptibility studies revealed that all isolates were multidrug resistant. although, ...	2009	23100781
antimicrobial susceptibility and molecular characterization of vibrio cholerae from cholera outbreaks in chennai.	the genotype and antibiotic resistance pattern of the toxigenic vibrio cholerae strains associated with cholera outbreaks vary frequently. fifty-one v. cholerae strains isolated from cholera outbreaks in chennai (2002-2005) were screened for the presence of virulence and regulatory genes by multiplex polymerase chain reaction (pcr) assay. genotyping of the isolates was done by vc1 primers derived from enterobacterial repetitive intergenic consensus (eric)-related sequence in v. cholerae. all the ...	2009	23100755
a semi-quantitative assessment of the histopathology of oral lichen planus.	in a retrospective study of 112 cases, an attempt has been made to further delineate the histopathological parameters which are useful in making a diagnosis of oral lichen planus. the results of this study show that mononuclear infiltration beneath and adjacent to the epithelium, parakeratosis and degeneration of the basal layer of the epithelium were consistent features. linear regression analyses of the parameters studied provided partial support for a cell-mediated immune mechanism.	2010	3091793
the use of dura mater allograft in the surgical repair of large defects of the abdominal wall.	the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ...	2010	3160130
the use of dura mater allograft in the surgical repair of large defects of the abdominal wall.	the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ...	2010	3160130
the history of hormone assays.		2010	3068672
[epileptics and their oral health].		2010	2937970
transient neonatal hypothyroidism in very low birthweight infants: is treatment necessary?		2010	2863505
anal duct carcinoma.		2010	2924675
heredity and blood pressure in humans: an overview.	this paper presents a review of the genetic transmission of normal blood pressure and of essential hypertension. familial aggregation of normal blood pressure has been reported in adults, in children and even in newborns. blood pressure aggregation phenomenon, however, is the result of both a genetic component and shared environmental factors. more specific for each etiological factor were the studies of blood pressure aggregation in twins and in adopted children. attention was focused on the mo ...	2010	3153263
studies on neurotransmitter markers and neuronal cell density in the cerebellar system in olivopontocerebellar atrophy and cortical cerebellar atrophy.	glutamate, aspartate and gamma-aminobutyrate (gaba) concentrations and choline acetyltransferase (chat) activity were measured in postmortem cerebellar cortical areas and brainstem nuclei of 10 normal controls, 5 patients of olivopontocerebellar atrophy (opca) with multiple system atrophy (msa) and 2 patients of cortical cerebellar atrophy (cca). in addition, the neuronal cell density in the cerebellar cortex and the brainstem nuclei was determined, and the correlation between neurotransmitter m ...	2010	2868072
effect of maternal rubella on hearing and vision: a twenty year post-epidemic study.	three years of research conducted at ntid beginning in 1984 examined the hearing and vision characteristics of two groups of deaf college students. all 242 students studied received complete audiometric assessments and ophthalmological examinations. of those students examined, 104 were known to be deaf as a result of maternal rubella (congenital rubella syndrome (crs) group). the remaining 138 (non-crs group) became deaf for a variety of other reasons. no significant differences were found betwe ...	2010	2816674
abnormal systolic time intervals in obesity and their relationship with the amount of overweight.	we studied 17 severely obese subjects (age range 26 to 42 years), without hypertension, diabetes mellitus, angina, or clinical signs of heart failure or respiratory disease, and 16 age-matched control subjects. x-teleroentgenographic findings (transverse cardiac diameter and cardiothoracic ratio), blood pressure, and mechanocardiographic parameters were analyzed in both groups. by means of conventional simultaneous recordings of ecg, phonocardiogram, and carotid pulse (100 mm/sec), systolic time ...	2010	2943149
lung cancer in northern india in relation to age, sex and smoking habits.	primary lung cancer in northern india was analysed in relation to age, sex and smoking history in 480 histologically diagnosed cases. the m:f ratio rose progressively up to the 51-60 years age group and was about the same thereafter. the m:f ratio was very high in smokers and was almost identical for all cell types (greater than 20:1). in non-smokers, the m:f ratio differed with the cell type. the smoker:non-smoker ratio differed significantly in the age groups below and above 40. in those up to ...	2010	3028854
lung cancer in northern india in relation to age, sex and smoking habits.	primary lung cancer in northern india was analysed in relation to age, sex and smoking history in 480 histologically diagnosed cases. the m:f ratio rose progressively up to the 51-60 years age group and was about the same thereafter. the m:f ratio was very high in smokers and was almost identical for all cell types (greater than 20:1). in non-smokers, the m:f ratio differed with the cell type. the smoker:non-smoker ratio differed significantly in the age groups below and above 40. in those up to ...	2010	3028854
influence of pontic material on alveolar mucosal conditions.	the purpose of the present study was to investigate plaque accumulation and inflammatory changes in the mucosa beneath fixed bridge pontics of various materials, in patients cleaning the infrapontic space daily. fixed bridges with a tight but non-compressive contact to the mucosa in the pontic area and with interchangeable test specimens placed in the pontic base were constructed for five patients. during 4-wk periods the following materials were tested: alloys with a high or a low gold content, ...	2010	3059449