Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| co-localized or randomly distributed? pair cross correlation of in vivo grown subgingival biofilm bacteria quantified by digital image analysis. | the polymicrobial nature of periodontal diseases is reflected by the diversity of phylotypes detected in subgingival plaque and the finding that consortia of suspected pathogens rather than single species are associated with disease development. a number of these microorganisms have been demonstrated in vitro to interact and enhance biofilm integration, survival or even pathogenic features. to examine the in vivo relevance of these proposed interactions, we extended the spatial arrangement analy ... | 2012 | 22655057 |
| serum antibodies to periodontal pathogens are a risk factor for alzheimer's disease. | chronic inflammation in periodontal disease has been suggested as a potential risk factor in alzheimer's disease (ad). the purpose of this study was to examine serum antibody levels to bacteria of periodontal disease in participants who eventually converted to ad compared with the antibody levels in control subjects. | 2012 | 22546352 |
| oral bacteria and yeasts in relationship to oral ulcerations in hematopoietic stem cell transplant recipients. | oral mucositis is a serious and debilitating side effect of conditioning regimens for hematopoietic stem cell transplant (hsct). through hsct, the homeostasis in the oral cavity is disrupted. the contribution of the oral microflora to mucositis remains to be clarified. the aim of our study was to investigate the relationship between yeasts, bacteria associated with periodontitis, and oral ulcerations in hsct recipients. | 2012 | 22531876 |
| acquisition of complement inhibitor serine protease factor i and its cofactors c4b-binding protein and factor h by prevotella intermedia. | infection with the gram-negative pathogen prevotella intermedia gives rise to periodontitis and a growing number of studies implies an association of p. intermedia with rheumatoid arthritis. the serine protease factor i (fi) is the central inhibitor of complement degrading complement components c3b and c4b in the presence of cofactors such as c4b-binding protein (c4bp) and factor h (fh). yet, the significance of complement inhibitor acquisition in p. intermedia infection and fi binding by gram-n ... | 2012 | 22514678 |
| treponema denticola chymotrypsin-like proteinase (ctlp) integrates spirochaetes within oral microbial communities. | treponema denticola is found ubiquitously in the human oral cavity and is mainly associated with bacterial communities implicated in the establishment and development of periodontal disease. the ability to become integrated within biofilm communities is crucial to the growth and survival of oral bacteria, and involves inter-bacterial coaggregation, metabolic cooperation, and synergy against host defences. in this article we show that the chymotrypsin-like proteinase (ctlp), found within a high-m ... | 2012 | 22313692 |
| evaluation of efficacy of tetracycline fibers in conjunction with scaling and root planing in patients with chronic periodontitis. | the objective of this study was to compare the efficacy of scaling and root planing (srp) alone versus tetracycline fiber therapy used adjunctively with srp in the treatment of chronic periodontitis sites in maintenance patients. | 2012 | 23162335 |
| bacterial diversity in oral samples of children in niger with acute noma, acute necrotizing gingivitis, and healthy controls. | noma is a gangrenous disease that leads to severe disfigurement of the face with high morbidity and mortality, but its etiology remains unknown. young children in developing countries are almost exclusively affected. the purpose of the study was to record and compare bacterial diversity in oral samples from children with or without acute noma or acute necrotizing gingivitis from a defined geographical region in niger by culture-independent molecular methods. | 2012 | 22413030 |
| antimicrobial constituents of artemisia afra jacq. ex willd. against periodontal pathogens. | the phytochemical investigation of an ethanol extract of artemisia afra led to the isolation of six known compounds, acacetin (1), 12α,4α-dihydroxybishopsolicepolide (2), scopoletin (3), α-amyrin (4), phytol (5), and a pentacyclic triterpenoid betulinic acid (6). the compounds were evaluated for antimicrobial activity against gram positive (actinomyces naeslundii, actinomyces israelii, and streptococcus mutans), gram negative bacteria (prevotella intermedia, porphyromonas gingivalis and aggregat ... | 2012 | 22693528 |
| the predominant bacteria isolated from radicular cysts. | to detect predominant bacteria associated with radicular cysts and discuss in light of the literature. | 2013 | 24011184 |
| analysis of bacterial flora associated with peri-implantitis using obligate anaerobic culture technique and 16s rdna gene sequence. | to analyze and characterize the predominant bacterial flora associated with peri-implantitis by using culture techniques under obligate anaerobic conditions and 16s rdna gene sequences. | 2013 | 24278920 |
| suppuration-associated bacteria in patients with chronic and aggressive periodontitis. | suppuration (sup) on probing may be an indication of active periodontal breakdown. the aim of the present study is to analyze which subgingival species are associated with sup in patients with chronic (cp) and aggressive (agp) periodontitis. | 2013 | 23327648 |
| microarray analysis of microbiota of gingival lesions in noma patients. | noma (cancrum oris) is a gangrenous disease of unknown etiology affecting the maxillo-facial region of young children in extremely limited resource countries. in an attempt to better understand the microbiological events occurring during this disease, we used phylogenetic and low-density microarrays targeting the 16s rrna gene to characterize the gingival flora of acute noma and acute necrotizing gingivitis (ang) lesions, and compared them to healthy control subjects of the same geographical and ... | 2013 | 24086784 |
| association of plasma 25-hydroxyvitamin d concentrations and pathogenic oral bacteria in postmenopausal females. | previous findings of an association between 25-hydroxyvitamin d [25(oh)d] concentrations and periodontal disease may be partially explained by the antimicrobial properties of vitamin d. to the best of the authors' knowledge, no study has investigated the association between 25(oh)d and pathogenic oral bacteria, a putative cause of periodontal disease. | 2013 | 24261910 |
| impact of early colonizers on in vitro subgingival biofilm formation. | the aim of this study was to investigate the impact of early colonizing species on the structure and the composition of the bacterial community developing in a subgingival 10-species biofilm model system. the model included streptococcus oralis, streptococcus anginosus, actinomycesoris, fusobacterium nucleatum subsp. nucleatum, veillonella dispar, campylobacter rectus, prevotella intermedia, porphyromonas gingivalis, tannerella forsythia, and treponema denticola. based on literature, we consider ... | 2013 | 24340084 |
| high incidence of aggregatibacter actinomycetemcomitans infection in patients with cerebral infarction and diabetic renal failure: a cross-sectional study. | recent epidemiological studies suggest that periodontitis is a major risk factor for renal failure and cerebral infarction. the aim of this study was to evaluate the association among periodontitis, renal failure, and cerebral infarction, focusing on microbiological and immunological features. | 2013 | 24267704 |
| bacteremia following scaling and root planing: a clinico-microbiological study. | bacteremia frequently occurs after treatment procedures such as extractions, scaling, root planing, periodontal surgery. there is currently significant interest in the possibility that bacteremia with oral bacteria may play role in pathogenesis of atherosclerosis. there are well-conducted studies that have determined the frequency of passage of periodontal microorganisms to the bloodstream after periodontal treatment. there is scarce information related to the incidence of periodontopathic micro ... | 2013 | 24554880 |
| determination of periodontopathogens in patients with cri du chat syndrome. | cri du chat syndrome is a genetic alteration associated with some oral pathologies. however, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. the purpose of this comparative study was to compare periodontopathogenic flora in a group with cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis. | 2013 | 24121919 |
| effect of controlled-release periochip™ on clinical and microbiological parameters in patients of chronic periodontitis. | the aim of the present study was to evaluate and compare the clinical and microbiological effectiveness of periochip™ as an adjunct to scaling and root planing (srp) with srp alone in patients with chronic periodontitis. | 2013 | 24174754 |
| quantitative analysis of periodontal pathogens present in the saliva of geriatric subjects. | at present, information regarding periodontal disease in geriatric patients is scarce. the purpose of this study was to quantify the periodontal pathogens present in the saliva of korean geriatric patients and assess the relationship between the bacterial levels and the periodontal condition. | 2013 | 24040571 |
| periodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitis. | oral lichen planus (olp) is a chronic inflammatory disease that is frequently detected in oral tissues. the aim of our study was to identify the prevalence of the detection of periodontopathogenic microorganisms (aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythia and treponema denticola in olp patients and to compare with this prevalence of periodontopathogenic microorganisms in healthy non-olp patients. our study included 27 (18 chronic ... | 2013 | 23743616 |
| short-term microbiological effects of scaling and root planing and essential-oils mouthwash in chinese adults. | to assess the short-term effect of scaling and root planing (srp) and essential-oils mouthwash on the levels of specific bacteria in chinese adults. | 2013 | 23645178 |
| subgingival microbial profiles as diagnostic markers of destructive periodontal diseases: a clinical epidemiology study. | to describe the subgingival microbial profiles of the major putative periodontal pathogens and investigate their role as diagnostic markers for destructive periodontal diseases in an untreated and isolated population. | 2013 | 22564019 |
| specificity of antimicrobial peptide ll-37 to neutralize periodontopathogenic lipopolysaccharide activity in human oral fibroblasts. | the antimicrobial peptide ll-37 is known to have a potent lipopolysaccharide (lps)-neutralizing activity in various cell types. because of observed heterogeneity within periodontopathogenic lps, the authors hypothesized that ll-37 had specificity to neutralize such lps activity. the present study, therefore, aims to investigate the lps-neutralizing activity of ll-37 to various periodontopathogenic lps in interleukin-8 (il-8) production after challenging them in human oral fibroblasts. | 2013 | 22443521 |
| peripheral arterial disease associated with caries and periodontal disease. | peripheral arterial disease (pad) is an important cardiovascular disorder of the peripheral arteries. chronic infections, such as periodontitis, may play an important role in the etiology and pathophysiology of pad and other cardiovascular conditions. recently, streptococcus mutans has been found with high frequency in atheromatous plaques. the aim of this study is to evaluate the possible clinical and microbiologic association between pad and periodontitis and dental caries. | 2013 | 22680302 |
| frequency of periodontal pathogens in equivalent peri-implant and periodontal clinical statuses. | this study tested the hypotheses that there is: (1) higher bacterial frequency in peri-implantitis/periodontitis, followed by mucositis/gingivitis and peri-implant/periodontal health; (2) similar bacterial frequency between comparable peri-implant and periodontal clinical statuses. | 2013 | 23127822 |
| the peri-implant health in patients attending an annual recall program. a clinical and microbiological study in 74 patients from the tübingen implant registry. | to describe the peri-implant condition of unselected implant recall patients, to relate it to relevant features from the patient medical history, and to look at associations across these findings. | 2013 | 22905716 |
| bacterial antagonism against periodontopathogens. | the aim of the current study is to compare the prevalence of commensal bacteria, with beneficial properties, for healthy and diseased individuals and additionally to examine the inhibitory effect of some commercial dietary probiotics on periodontopathogens, comparing this inhibitory effect to that of orally derived beneficial bacteria. | 2013 | 22897652 |
| a double-blind randomized placebo-controlled study on the clinical and microbial effects of an essential oil mouth rinse used by patients in supportive periodontal care. | this 3-month double-blind randomized placebo-controlled study evaluated the clinical and microbial effects of an essential oil mouth rinse used as an adjunct to mechanical plaque control by patients in supportive periodontal care. | 2013 | 22998386 |
| influence of periodontal status and periodontopathogens on levels of oral human β-defensin-2 in saliva. | expression patterns of human β-defensin-2 (hbd-2) mrna or hbd-2 protein concentration and periodontal diseases have been a focus of scientific research. this study compares the salivary levels of hbd-2 protein concentration of healthy patients and patients with gingivitis and chronic periodontitis (cp) and correlates these levels with the presence of periodontopathogens. | 2013 | 23173827 |
| does photodynamic therapy enhance standard antibacterial therapy in dentistry? | the aim of this study was to assess whether or not photodynamic therapy enhanced standard antibacterial therapy in dentistry. | 2013 | 24138192 |
| rheumatoid arthritis is an autoimmune disease caused by periodontal pathogens. | a statistically significant association between periodontal disease (pd) and systemic diseases has been identified. rheumatoid arthritis (ra), which is a chronic inflammatory joint disease, exhibits similar characteristics and pathogenesis to pd. the association between ra and pd has been investigated, and numerous publications on this subject exist. approximately 20 bacterial species have been identified as periodontal pathogens, and these organisms are linked to various types of pd. the most a ... | 2013 | 23737674 |
| comparative evaluation of subgingival plaque microflora in pregnant and non-pregnant women: a clinical and microbiologic study. | gingival changes in pregnancy have been attributed to changes in the subgingival biofilm related to hormonal variations. | 2013 | 23633772 |
| detection of oral bacterial dna in synovial fluid. | as periodontal bacteria might be involved in the aetiology of rheumatic diseases, we analysed synovial fluid obtained from patients with rheumatoid arthritis (ra) and controls for the presence of dna of aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythia, and treponema denticola. | 2013 | 23534379 |
| prevalence of periodontal pathogens and metabolic control of type 1 diabetes patients. | the aim of the study was to evaluate the prevalence of periodontal pathogens aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythia and treponema denticola in subgingival plaque collected at different probing depths of type 1 diabetes patients with periodontal disease in correlation to metabolic control. | 2013 | 23413629 |
| in vitro antimicrobial effects of two antihalitosis mouth rinses on oral pathogens and human tongue microbiota. | the aim of the study was to compare the antimicrobial activity of a mouth rinse containing chlorhexidine and cetylpyridinium chloride (mr1) with a stannous fluoride-based mouth rinse (mr2) in vitro. | 2013 | 23368885 |
| [evaluation on antimicrobial efficacy of fufang bingpeng irrigant: an in vitro study]. | to evaluate the antimicrobial efficacy of fufang bingpeng irrigant and bingpeng irrigant on four endodontic pathogen bacteria. | 2013 | 23991570 |
| [analysis of antimicrobial effect of mtad solution in infected root canal system using pcr technique]. | clinically acceptable antiseptic should possess organolithic-mineralolithic properties and antimicrobial efficacy, and should be non-toxic. | 2013 | 23745336 |
| microbiological profile and antimicrobial susceptibility pattern of infected root canals associated with periapical abscesses. | the aim of this investigation was to identify microorganisms from root canals with periapical abscesses and assess the susceptibility of specific anaerobic bacteria to selected antimicrobials and their β-lactamase production. sixty root canals were microbiologically investigated. the susceptibility of anaerococcus prevotii, fusobacterium necrophorum, f. nucleatum, parvimonas micra, and prevotella intermedia/nigrescens to antimicrobials was evaluated with the etest, whereas β-lactamase production ... | 2013 | 23224675 |
| an investigation of the presence of specific anaerobic species in necrotic primary teeth. | different microbial identification methods have shown that the microbial community profiles in endodontic infections are diverse and assorted. the aim of this study was to evaluate the frequency of selected endodontic pathogens in the pulp chambers (pcs) and root canals (rcs) of infected primary teeth using pcr methods. paired pc and rc samples were collected from 15 subjects and analyzed by pcr for the presence of filifactor alocis, fusobacterium nucleatum, parvimonas micra, porphyromonas endod ... | 2013 | 23538426 |
| viability reagent, prestoblue, in comparison with other available reagents, utilized in cytotoxicity and antimicrobial assays. | this study compared different commercially available viability reagents. the growth indicator reagents include p-iodonitrotetrazolium violet (int), prestoblue, and alamar blue which were used for antimicrobial analysis against streptococcus mutans, prevotella intermedia, propionibacterium acnes, and mycobacterium tuberculosis. prestoblue and alamar blue are resazurin based reagents that resulted in a quick and easily distinguishable colour change that allowed for visual readings. int and sodium ... | 2013 | 23653650 |
| the effects of stress hormones on growth of selected periodontitis related bacteria. | the focus of this study was to examine in vitro the effects of stress hormones (catecholamines: epinephrine, norepinephrine, dopamine and hydrocortisone: cortisol) on the growth of four anaerobic species of periodontitis-related bacteria (fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia and tannerella forsythia) and one facultative anaerobic species (eikenella corrodens). bacterial growth was determined by two different methods: fluorescence in situ hybridization (fish), ... | 2013 | 24036419 |
| hyaluronic acid as an adjunct after scaling and root planing: a prospective randomized clinical trial. | the study is designed to determine the effect on clinical variables, subgingival bacteria, and local immune response brought about by application of hyaluronan-containing gels in early wound healing after scaling and root planing (srp). | 2013 | 23088524 |
| antimicrobial efficacy of 0·05% cetylpyridinium chloride mouthrinses. | this study evaluated the antimicrobial activity of two commercially available 0·05% cetylpyridinium chloride (cpc) mouthrinses with or without alcohol and examined its antimicrobial activity on oral bacterial species including fresh clinical isolates compared to a chlorhexidine mouthrinse and a control fluoride mouthrinse without cpc. two different approaches were used to evaluate antimicrobial activity. first, the minimum inhibitory concentration (mic) was determined for each mouthrinse against ... | 2013 | 23039819 |
| adjuvant activity of naturally occurring monophosphoryl lipopolysaccharide preparations from mucosa-associated bacteria. | natural heterogeneity in the structure of the lipid a portion of lipopolysaccharide (lps) produces differential effects on the innate immune response. gram-negative bacterial species produce lps structures that differ from the classic endotoxic lps structures. these differences include hypoacylation and hypophosphorylation of the diglucosamine backbone, both differences known to decrease lps toxicity. the effect of decreased toxicity on the adjuvant properties of many of these lps structures has ... | 2013 | 23798540 |
| clinical and microbiological evaluation of high intensity diode laser adjutant to non-surgical periodontal treatment: a 6-month clinical trial. | this randomized split-mouth clinical trial was designed to evaluate the efficacy of scaling and root planing associated to the high-intensity diode laser on periodontal therapy by means of clinical parameters and microbial reduction. | 2013 | 22402617 |
| clinical and microbiological parameters in patients with self-ligating and conventional brackets during early phase of orthodontic treatment. | to determine the effect of different bracket designs (conventional brackets and self-ligating brackets) on periodontal clinical parameters and periodontal pathogens in subgingival plaque. | 2013 | 22765511 |
| the antibacterial activity of various saturated and unsaturated fatty acids against several oral pathogens. | the antibacterial activity of various saturated fatty acids (sfa) and unsaturated fatty acids (usfa) against different oral pathogens which are implicated in the cause of dental caries, stomatitis, gingivitis, and periodontitis was examined. the saturated fatty acids pa, sta and ara, and the unsaturated omega-7 fatty acids pla and omega-9 fatty acids oa showed either none to low antimicrobial activity against all of the 12 oral pathogenic strains used in this study. in contrast, the omega-3 pufa ... | 2013 | 24640241 |
| antimicrobial activities of stearidonic and gamma-linolenic acids from the green seaweed enteromorpha linza against several oral pathogenic bacteria. | we found that the edible green seaweed enteromorpha linza displayed potent antimicrobial activity against prevotella intermedia and porphyromonas gingivalis. to elucidate the active component of e. linza, isolation procedures were performed. | 2013 | 28510876 |
| effect of quercetin on the production of nitric oxide in murine macrophages stimulated with lipopolysaccharide from prevotella intermedia. | nitric oxide (no) is a short-lived bioactive molecule that is known to play an important role in the pathogenesis of periodontal disease. in the current study, we investigated the effect of the flavonoid quercetin on the production of no in murine macrophages activated with lipopolysaccharide (lps) from prevotella intermedia, a pathogen related to inflammatory periodontal disease, and tried to elucidate the underlying mechanisms of action. | 2013 | 24040572 |
| efficacy of a new mouth rinse formulation based on 0.07% cetylpyridinium chloride in the control of plaque and gingivitis: a 6-month randomized clinical trial. | to assess the efficacy of a 0.07% cetylpyridinium chloride (cpc) mouth rinse in the control of plaque and gingival inflammation during a 6-month period. | 2013 | 24024983 |
| isorhamnetin inhibits prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages via anti-inflammatory heme oxygenase-1 induction and inhibition of nuclear factor-κb and signal transducer and activator of transcription 1 activation. | interleukin-6 (il-6) is a key proinflammatory cytokine that has been considered to be important in the pathogenesis of periodontal disease. therefore, host-modulatory agents directed at inhibiting il-6 appear to be beneficial in terms of attenuating periodontal disease progression and potentially improving disease susceptibility. in the current study, we investigated the effect of the flavonoid isorhamnetin on the production of il-6 in murine macrophages stimulated with lipopolysaccharide (lps) ... | 2013 | 23441850 |
| antibacterial and antibiofilm effects of iron chelators against prevotella intermedia. | prevotella intermedia, a major periodontopathogen, has been shown to be resistant to many antibiotics. in the present study, we examined the effect of the fda-approved iron chelators deferoxamine (dfo) and deferasirox (dfra) against planktonic and biofilm cells of p. intermedia in order to evaluate the possibility of using these iron chelators as alternative control agents against p. intermedia. dfra showed strong antimicrobial activity (mic and mbc values of 0.16 mg ml(-1)) against planktonic p ... | 2013 | 23329319 |
| the sociodemographic characteristics, periodontal health status, and subgingival microbiota of patients with chronic periodontitis and type 2 diabetes mellitus: a case-control study in a chinese population. | in china, chronic periodontitis (cp) is common in patients with type 2 diabetes mellitus (t2dm). the purpose of this study is to identify the sociodemographic characteristics associated with such patients and to assess the periodontal health status and subgingival microbiota of patients with cp and t2dm (t2dmcp) in the chinese population. | 2013 | 23030242 |
| kaempferol inhibits p. intermedia lipopolysaccharide-induced production of nitric oxide through translational regulation in murine macrophages: critical role of heme oxygenase-1-mediated ros reduction. | nitric oxide (no) could be a potential target for the development of new therapeutic approaches to the treatment of periodontal disease because this molecule plays a significant role in the tissue destruction observed in periodontitis. in this study, the authors investigate the effect of kaempferol on the production of no by murine macrophage-like raw264.7 cells stimulated with lipopolysaccharide (lps) from prevotella intermedia, a pathogen implicated in periodontal disease, and try to determine ... | 2013 | 22769443 |
| association of periodontitis with increased colonization by prevotella nigrescens. | to estimate differences in the prevalence of prevotella intermedia and prevotella nigrescens in the subgingival plaque of patients with periodontitis (including aggressive and advanced chronic periodontitis) compared to healthy controls, and to search for significant associations with clinical status. | 2013 | 22767485 |
| [quantitative real-time pcr for target periodontal bacteria in subgingival plaque before and after local delivery of periocline, scaling and root planning]. | to compare the copy number of porphyromonas gingivalis (pg) and prevotella intermedia (pi) in subgingival plaque before and after local delivery of periocline (2% minocycline hydrochloride ointment, mo), scaling and root planning (srp) by quantitative real-time pcr (qrt-pcr) and evaluate the efficacy. | 2013 | 23852060 |
| altered phenotype and function of dendritic cells in individuals with chronic periodontitis. | to investigate the effects of periodontal bacterial lysates on maturation and function of mature monocyte-derived dendritic cells (m-mddcs) derived from individuals with chronic periodontitis (cp) or healthy periodontal tissue (hp). | 2013 | 23623310 |
| evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the hmuy haemophore of porphyromonas gingivalis and the cysteine protease interpain a (inpa) of prevotella intermedia. | haem (iron protoporphyrin ix) is both an essential growth factor and a virulence regulator of the periodontal pathogens porphyromonas gingivalis and prevotella intermedia, which acquire it through the proteolytic degradation of haemoglobin and other haem-carrying plasma proteins. the haem-binding lipoprotein hmuy haemophore and the gingipain proteases of p. gingivalis form a unique synthrophic system responsible for capture of haem from haemoglobin and methaemalbumin. in this system, methaemoglo ... | 2013 | 23336115 |
| prediction of periodontopathic bacteria in dental plaque of periodontal healthy subjects by measurement of volatile sulfur compounds in mouth air. | the aim of this study was to determine whether measurements of volatile sulfur compounds (vscs) are useful to predict colonization of periodontopathic bacteria. for this purpose, we assessed the relationships among distributions of 4 species of periodontopathic bacteria in tongue coating and dental plaque, oral conditions including vsc concentration in mouth air, and smoking habit of periodontal healthy young subjects. | 2013 | 23107050 |
| [relationships of five periodontal pathogens causing subgingival plaque in patients with chronic periodontitis under different periodontal conditions]. | this study aimed to assess the relationship between the distributions of haemophilus aggregatibacter (h. aggregatibacter ), porphyromonas gingivalis (p. gingivalis ), prevotella intermedia (p. intermedia), tannerella forsythensis (t. forsythensis), and treponema denticola (t. denticola) in subgingival plaque and different periodontal conditions of chronic periodontitis. | 2013 | 24298807 |
| the influence of oral bacteria on epithelial cell migration in vitro. | oral ulcerations often arise as a side effect from chemo- and radiation therapy. in a previous clinical study, porphyromonas gingivalis was identified as a positive predictor for oral ulcerations after hematopoetic stem cell transplantation, possibly incriminating p. gingivalis in delayed healing of the ulcerations. therefore, it was tested whether p. gingivalis and its secreted products could inhibit the migration of oral epithelial cells in an in vitro scratch assay. to compare, the oral bacte ... | 2013 | 24288439 |
| human neutrophil defensins and their effect on epithelial cells. | the aims of the present study include: 1) to localize human neutrophil defensin-1 (hnp-1) through hnp-3 in gingiva and in neutrophil extract-treated epithelial cell monolayers; 2) to determine the effects of hnp-1 on the epithelial cell viability, attachment, and spreading; and 3) to analyze the effect of hnp-1 on the bacterial adherence to epithelial cells. | 2013 | 22443519 |
| method to quantify live and dead cells in multi-species oral biofilm by real-time pcr with propidium monoazide. | real-time pcr (qpcr) is a widely used technique in analysing environmental and clinical microbiological samples. however, its main limitation was its inability to discriminate between live and dead cells.recently, propidium monoazide (pma) together with qpcr has been used to overcome this problem, with good results for different bacterial species in different types of samples.our objective was to implement this technique for analysing mortality in multi-species oral biofilms formed in vitro with ... | 2013 | 23289803 |
| presence of oral bacterial species in primary endodontic infections of primary teeth. | knowledge of the microbial composition of deciduous endodontic infections is limited. this study aimed to evaluate the presence of the 10 oral bacterial species in samples from primary tooth root canals by using microarray technology and to determine the association of these organisms with clinical conditions. | 2013 | 24683780 |
| prevalence of β-lactamase-producing bacteria in human periodontitis. | beta-lactam antibiotics prescribed in periodontal therapy are vulnerable to degradation by bacterial β-lactamases. this study evaluated the occurrence of β-lactamase-positive subgingival bacteria in chronic periodontitis subjects of usa origin, and assessed their in vitro resistance to metronidazole at a breakpoint concentration of 4 μg/ml. | 2013 | 23173872 |
| long-term follow-up of turned single implants placed in periodontally healthy patients after 16 to 22 years: microbiologic outcome. | survival rates in implant dentistry today are high, although late failures do occur for many reasons, including peri-implant infections. the primary objective of this study is to investigate microbiota around single turned implants after 16 to 22 years. secondary objectives are to compare teeth and implants and to correlate microbiologic, radiographic, and clinical parameters. | 2013 | 22934839 |
| protein substrates of a novel secretion system are numerous in the bacteroidetes phylum and have in common a cleavable c-terminal secretion signal, extensive post-translational modification, and cell-surface attachment. | the secretion of certain proteins in porphyromonas gingivalis is dependent on a c-terminal domain (ctd). after secretion, the ctd is cleaved prior to extensive modification of the mature protein, probably with lipopolysaccharide, therefore enabling attachment to the cell surface. in this study, bioinformatic analyses of the ctd demonstrated the presence of three conserved sequence motifs. these motifs were used to construct hidden markov models (hmms) that predicted 663 ctd-containing proteins i ... | 2013 | 24007199 |
| pleural effusion due to streptococcus milleri: case descriptions. | in this study we analyzed the characteristics of patients with pleural effusion secondary to streptococcus milleri studied retrospectively between january and march 2013 and found seven patients with a mean age of 60 years, 43% of which were smokers and 57% with a drinking habit. the most common associated factors were alcoholism, previous pneumonia and diabetes. other bacteria were identified as enterobacter aerogenes, bacteroides and prevotella intermedia capillosus in two patients. the mean d ... | 2014 | 24439468 |
| [comparison of the effects of ginkgo biloba extract and minocycline hydrochlovide on periodontitis]. | to compare the clinical effect of ginkgo biloba extract gel (ginkgo biloba extract,egb) and minocycline hydrochloride (periocline) on periodontitis and their inhibition on putative periodontal pathogens. | 2014 | 25199931 |
| periodontal bacteria in human carotid atherothrombosis as a potential trigger for neutrophil activation. | epidemiological, biological and clinical links between periodontal and cardiovascular diseases are now well established. several human studies have detected bacterial dna corresponding to periodontal pathogens in cardiovascular samples. intraplaque hemorrhage has been associated with a higher risk of atherosclerotic plaque rupture, potentially mediated by neutrophil activation. in this study, we hypothesized that plaque composition may be related to periodontal pathogens. | 2014 | 25173070 |
| evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model. | various antibacterial and antiplaque agents are used in chemical plaque control but none are without their shortcomings. chlorhexidine considered a gold standard, also has an array of side effects. to overcome these, numerous herbal extracts have been tried and tested and one among them is holy basil. the present study evaluated the antibacterial efficacy of holy basil in vitro against some periodontopathogens and its antiplaque effect in vivo. | 2014 | 25674314 |
| novel therapeutic approach for the treatment of periodontitis by curcumin. | the aim of the present study was to evaluate the clinical and microbiological efficacy of locally delivered 1% curcumin gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis. | 2014 | 25654035 |
| synthesis and biological activities of 2,6-dihydroxy-4-isopentenyloxychalcone as an antimicrobial and anti-inflammatory compound. | chalcones are a group of plant-derived polyphenolic compounds possessing a wide variety of biological activities. the aim of this study was to synthesize 2,6-dihydroxy-4-isopentenyloxychalcone (1), a chalcone found in plants belonging to the genera helichrysum, pleiotaxix and metalasia, and evaluate its antimicrobial effects against major oral pathogens as well as its anti-inflammatory properties. compound 1 was synthesized using a simple two-step procedure. among the seven pathogens tested, por ... | 2014 | 23859000 |
| effects of ginkgo biloba extract on periodontal pathogens and its clinical efficacy as adjuvant treatment. | to determine the effects of ginkgo biloba extract (egb) on major periodontal pathogens in subgingival plaque. | 2014 | 25098260 |
| effects of systemic administration of sitafloxacin on subgingival microflora and antimicrobial susceptibility profile in acute periodontal lesions. | the aim of this study was to assess the effect(s) of systemic administration of sitafloxacin on subgingival microbial profiles of acute periodontal lesions. antimicrobial susceptibility of clinical isolates was also investigated. patients with acute phases of chronic periodontitis were subjected to clinical examination and microbiological assessment of their subgingival plaque samples by culture technique. sitafloxacin was then administered (100 mg/day for 5 days) systemically. the clinical and ... | 2014 | 24747615 |
| molecular analysis of oral bacteria in dental biofilm and atherosclerotic plaques of patients with vascular disease. | oral bacteria have been detected in atherosclerotic plaques at a variable frequency; however, the connection between oral health and vascular and oral bacterial profiles of patients with vascular disease is not clearly established. the aim of this study was to evaluate the presence of oral bacterial dna in the mouth and atherosclerotic plaques, in addition to assessing the patients' caries and periodontal disease history. | 2014 | 24820755 |
| antibiotic resistance in human peri-implantitis microbiota. | because antimicrobial therapy is often employed in the treatment of infectious dental implant complications, this study determined the occurrence of in vitro antibiotic resistance among putative peri-implantitis bacterial pathogens. | 2014 | 23551701 |
| noma affected children from niger have distinct oral microbial communities based on high-throughput sequencing of 16s rrna gene fragments. | we aim to understand the microbial ecology of noma (cancrum oris), a devastating ancient illness which causes severe facial disfigurement in>140,000 malnourished children every year. the cause of noma is still elusive. a chaotic mix of microbial infection, oral hygiene and weakened immune system likely contribute to the development of oral lesions. these lesions are a plausible entry point for unidentified microorganisms that trigger gangrenous facial infections. to catalog bacteria present in n ... | 2014 | 25474262 |
| [nug--necrotizing ulcerative gingivitis: a review]. | necrotizing ulcerative gingivitis (nug) is an acute and rare (0.5-11% of the population) infectious disease of the gum tissue, which is characterized by ulceration and inflammation of the inter-dental gum tissue. nug was documented by historians since the fourth century bc, most of the reports from the ancient world were in the context of illness among fighting troops, present studies of nug in the modern world are still common among soldiers. nug is associated with poor oral hygiene and weakeni ... | 2014 | 25219100 |
| overexpression of receptor for advanced glycation end products and high-mobility group box 1 in human dental pulp inflammation. | high mobility group box 1 (hmgb1), a nonhistone dna-binding protein, is released into the extracellular space and promotes inflammation. hmgb1 binds to related cell signaling transduction receptors, including receptor for advanced glycation end products (rage), which actively participate in vascular and inflammatory diseases. the aim of this study was to examine whether rage and hmgb1 are involved in the pathogenesis of pulpitis and investigate the effect of prevotella intermedia (p. intermedia) ... | 2014 | 25114379 |
| [effect of er:yag laser on the dynamic changes in subgingival flora in type 2 diabetic patients with periodontitis]. | to observe the changes in subgingival microflora before and after er:yag laser treatment on diabetic patients with periodontitis, and to compare with the subgingival microflora of chronic periodontitis. | 2014 | 24881214 |
| development and evaluation of new primers for pcr-based identification of prevotella intermedia. | the aim of this study was to develop new prevotella intermedia-specific pcr primers based on the 16s rrna. the new primer set, pi-192 and pi-468, increased the accuracy of pcr-based p. intermedia identification and could be useful in the detection of p. intermedia as well as epidemiological studies on periodontal disease. | 2014 | 24875331 |
| interaction of prevotella intermedia strain 17 leucine-rich repeat domain protein adpf with eukaryotic cells promotes bacterial internalization. | prevotella intermedia is an oral bacterium implicated in a variety of oral diseases. although internalization of this bacterium by nonphagocytic host cells is well established, the molecular players mediating the process are not well known. here, the properties of a leucine-rich repeat (lrr) domain protein, designated adpf, are described. this protein contains a leucine-rich region composed of 663 amino acid residues, and molecular modeling shows that it folds into a classical curved solenoid st ... | 2014 | 24711565 |
| the anti-adhesive mode of action of a purified mushroom (lentinus edodes) extract with anticaries and antigingivitis properties in two oral bacterial phatogens. | in previous works we have shown that a low-molecular-mass (lmm) fraction from mushroom (lentinus edodes) homogenate interferes with binding of streptococcus mutans to hydroxyapatite and prevotella intermedia to gingival cells. additionally, inhibition of biofilm formation of both odonto- and periodonto-pathogenic bacteria and detachment from preformed biofilms have been described for this compound. further purification of mushroom extract has been recently achieved and a sub-fraction (i.e. # 5) ... | 2014 | 24564835 |
| effect of azithromycin on prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages. | interleukin-6 (il-6) is a key proinflammatory cytokine which plays a central role in the pathogenesis of periodontal disease. host modulatory agents targeting at inhibiting il-6, therefore, appear to be beneficial in slowing the progression of periodontal disease and potentially reducing destructive aspects of the host response. the present study was designed to investigate the effect of the macrolide antibiotic azithromycin on il-6 generation in murine macrophages treated with lipopolysaccharid ... | 2014 | 24534490 |
| comparison of osseointegration on various implant surfaces after bacterial contamination and cleaning: a rabbit study. | to examine the osseointegration of various implant surfaces after bacterial contamination and cleaning. | 2014 | 24451851 |
| protective effect of an egg yolk-derived immunoglobulin (igy) against prevotella intermedia-mediated gingivitis. | to investigate the effects of an egg yolk-derived immunoglobulin (igy) specific to prevotella intermedia in vitro and in vivo. | 2014 | 24320204 |
| dha suppresses prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. | several reports have indicated that dietary intake of dha is associated with lower prevalence of periodontitis. in the present study, we investigated the effect of dha on the production of proinflammatory mediators in murine macrophage-like raw264.7 cells stimulated with lipopolysaccharide (lps) isolated from prevotella intermedia, a pathogen implicated in inflammatory periodontal disease, and its mechanisms of action. lps was isolated from lyophilised p. intermedia atcc 25,611 cells using the s ... | 2014 | 24252501 |
| detection of eight periodontal microorganisms and distribution of porphyromonas gingivalis fima genotypes in chinese patients with aggressive periodontitis. | the microbiologic feature of aggressive periodontitis (agp) in chinese patients has not yet been determined. this study aims to investigate the prevalence of eight periodontal microorganisms and the distribution of the porphyromonas gingivalis fima genotype in a cohort of chinese patients with agp. | 2014 | 23646850 |
| the influence of incubation time, sample preparation and exposure to oxygen on the quality of the maldi-tof ms spectrum of anaerobic bacteria. | with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms), bacteria can be identified quickly and reliably. this accounts especially for anaerobic bacteria. because growth rate and oxygen sensitivity differ among anaerobic bacteria, we aimed to study the influence of incubation time, exposure to oxygen and sample preparation on the quality of the spectrum using the bruker system. also, reproducibility and inter-examiner variability were determined. twenty-s ... | 2014 | 25039504 |
| molecular identification and antibiotic resistant bacteria isolated from primary dentition infections. | bacterial resistance to antibiotics is a health problem in many parts of the world. the aim of this study was to identify bacteria from dental infections and determine bacterial resistance to antibiotics used in dental care in the primary dentition. | 2014 | 25091293 |
| relationship between halitosis and periodontal disease - associated oral bacteria in tongue coatings. | the objective of our study was to investigate the relationship between halitosis and oral bacteria in tongue coating (tc) and saliva samples from patients with halitosis, and to evaluate the effect of tongue cleaning on halitosis. | 2014 | 23890391 |
| antimicrobial efficacy of punica granatum mesocarp, nelumbo nucifera leaf, psidium guajava leaf and coffea canephora extract on common oral pathogens: an in-vitro study. | alternative therapies are increasingly being explored as extensive use of synthetic chemicals has led to the emergence of substantial side effects. phytomedicine has been well practiced as traditional medicine in various cultures for treatment of oral diseases. it has gained importance of late as an alternative to the conventional therapy. various plant and fruit extracts have been monitored recently to assess their potential against the common oral pathogens. aim of this study was to assess in- ... | 2014 | 25177642 |
| predicting the influence of multiple components on microbial inhibition using a logistic response model--a novel approach. | there are several synergistic methods available. however, there is a vast discrepancy in the interpretation of the synergistic results. also, these synergistic methods do not assess the influence the tested components (drugs, plant and natural extracts), have upon one another, when more than two components are combined. | 2014 | 24928297 |
| antagonistic effect of protein extracts from streptococcus sanguinis on pathogenic bacteria and fungi of the oral cavity. | an antibacterial substance from streptococcus sanguinis (s. sanguinis) is known to have an inhibitory effect on putative periodontal pathogens, but its inhibitory effect on pathogens of oral candidiasis is unknown. in this study, intracellular and exocrine proteins were extracted from s. sanguinis. the antagonistic effect of the protein extracts on prevotella intermedia (p. intermedia) and porphyromonas gingivalis (p. gingivalis) was detected by a well-plate technique, and the effects of the pro ... | 2014 | 24926331 |
| [effects of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions]. | to investigate the effect of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions. | 2014 | 25263382 |
| pathogenic bacterial species associated with endodontic infection evade innate immune control by disabling neutrophils. | endodontic infections, in which oral bacteria access the tooth pulp chamber, are common and do not resolve once established. to investigate the effects of these infections on the innate immune response, we established a mouse subcutaneous chamber model, where a mixture of four oral pathogens commonly associated with these infections (endodontic pathogens [ep]), i.e., fusobacterium nucleatum, streptococcus intermedius, parvimonas micra, and prevotella intermedia, was inoculated into subcutaneousl ... | 2014 | 25024367 |
| effects of stress hormones on the production of volatile sulfur compounds by periodontopathogenic bacteria. | little is known about the effects of stress hormones on the etiologic agents of halitosis. thus, the aim of this study was to evaluate in vitro the effects of adrenaline (adr), noradrenaline (na) and cortisol (cort) on bacteria that produce volatile sulfur compounds (vsc), the major gases responsible for bad breath. cultures of fusobacterium nucleatum (fn), porphyromonas endodontalis (pe), prevotella intermedia (pi) and porphyromonas gingivalis (pg) were exposed to 50 µm adr, na and cort or equi ... | 2014 | 24918364 |
| microbial profile of root canals of primary teeth with pulp necrosis and periradicular lesion. | the purpose of this study was to assess the microbial content of root canals of human primary teeth with pulp necrosis and periradicular lesion. | 2014 | 24709428 |
| antimicrobial activities against periodontopathic bacteria of pittosporum tobira and its active compound. | the study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. five hundred and fifty eight korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum. among the various medicinal plants, the alcohol extract of pittosporum tobira, which significantly exhibited antibacteria ... | 2014 | 24662076 |